SIMILAR PATTERNS OF AMINO ACIDS FOR 4R38_C_RBFC201_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dy2 | COLLAGEN ALPHA1(XV)CHAIN (Mus musculus) |
PF06482(Endostatin) | 5 | ILE A 246VAL A 150LEU A 151ILE A 170PHE A 121 | None | 1.34A | 4r38C-1dy2A:undetectable | 4r38C-1dy2A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0t | PYRUVATE KINASE (Escherichiacoli) |
PF00224(PK)PF02887(PK_C) | 5 | THR A 95VAL A 163LEU A 160ILE A 165PHE A 93 | None | 1.17A | 4r38C-1e0tA:undetectable | 4r38C-1e0tA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hdi | PHOSPHOGLYCERATEKINASE (Sus scrofa) |
PF00162(PGK) | 5 | ILE A 252LEU A 268LEU A 281ILE A 279PHE A 241 | None | 1.13A | 4r38C-1hdiA:undetectable | 4r38C-1hdiA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hjv | CHITINASE-3 LIKEPROTEIN 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 5 | THR A 260ASN A 374LEU A 24LEU A 46ILE A 54 | None | 1.19A | 4r38C-1hjvA:0.0 | 4r38C-1hjvA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hjv | CHITINASE-3 LIKEPROTEIN 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 5 | THR A 260LEU A 24LEU A 46ILE A 54PHE A 359 | None | 1.27A | 4r38C-1hjvA:0.0 | 4r38C-1hjvA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kae | HISTIDINOLDEHYDROGENASE (Escherichiacoli) |
PF00815(Histidinol_dh) | 5 | ASN A 321LEU A 240VAL A 339LEU A 338ILE A 330 | None | 1.24A | 4r38C-1kaeA:undetectable | 4r38C-1kaeA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kob | TWITCHIN (Aplysiacalifornica) |
PF00069(Pkinase) | 5 | THR A 94ILE A 101VAL A 209LEU A 197ILE A 364 | None | 1.08A | 4r38C-1kobA:0.9 | 4r38C-1kobA:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nij | HYPOTHETICAL PROTEINYJIA (Escherichiacoli) |
PF02492(cobW)PF07683(CobW_C) | 5 | THR A 55ILE A 89VAL A 95LEU A 94ILE A 96 | None | 1.04A | 4r38C-1nijA:1.9 | 4r38C-1nijA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1or4 | HEME-BASEDAEROTACTICTRANSDUCER HEMAT (Bacillussubtilis) |
PF11563(Protoglobin) | 5 | ILE A 100LEU A 79VAL A 89LEU A 92ILE A 83 | NoneHEM A 180 (-4.1A)NoneCYN A 181 (-3.5A)None | 1.20A | 4r38C-1or4A:undetectable | 4r38C-1or4A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tqy | ACTINORHODINPOLYKETIDE PUTATIVEBETA-KETOACYLSYNTHASE 1 (Streptomycescoelicolor) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | THR A 400ILE A 351LEU A 363VAL A 10ILE A 7 | MG A1095 (-3.9A)NoneNoneNoneNone | 1.26A | 4r38C-1tqyA:undetectable | 4r38C-1tqyA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tz9 | MANNONATEDEHYDRATASE (Enterococcusfaecalis) |
PF03786(UxuA) | 5 | ILE A 194LEU A 228VAL A 183LEU A 186ILE A 221 | None | 1.25A | 4r38C-1tz9A:undetectable | 4r38C-1tz9A:15.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1y | HYPOTHETICAL PROTEINTT0321 (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | ILE A 22ASN A 83VAL A 174ILE A 172PHE A 26 | None | 1.34A | 4r38C-2d1yA:undetectable | 4r38C-2d1yA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6m | WERNER SYNDROMEATP-DEPENDENTHELICASE HOMOLOG (Mus musculus) |
PF01612(DNA_pol_A_exo1) | 5 | GLU A 78LEU A 215VAL A 132LEU A 171ILE A 217 | NoneNoneNoneSO4 A 501 (-3.9A)None | 1.32A | 4r38C-2e6mA:undetectable | 4r38C-2e6mA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g5g | PUTATIVE LIPOPROTEIN (Campylobacterjejuni) |
PF04187(Cofac_haem_bdg) | 5 | THR X 221ILE X 240LEU X 215LEU X 36ILE X 60 | None | 1.31A | 4r38C-2g5gX:undetectable | 4r38C-2g5gX:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gf9 | RAS-RELATED PROTEINRAB-3D (Homo sapiens) |
PF00071(Ras) | 5 | ILE A 71LEU A 39VAL A 175LEU A 179PHE A 23 | None | 1.17A | 4r38C-2gf9A:undetectable | 4r38C-2gf9A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hcb | CHROMOSOMALREPLICATIONINITIATOR PROTEINDNAA (Aquifexaeolicus) |
PF00308(Bac_DnaA)PF08299(Bac_DnaA_C) | 5 | GLU A 271LEU A 305VAL A 320LEU A 324ILE A 308 | None | 1.33A | 4r38C-2hcbA:undetectable | 4r38C-2hcbA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | THR A 751GLU A 731LEU A 464ILE A 462PHE A 728 | None | 1.17A | 4r38C-2iujA:undetectable | 4r38C-2iujA:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgq | TRIOSEPHOSPHATEISOMERASE (Helicobacterpylori) |
PF00121(TIM) | 5 | ILE A 118LEU A 140LEU A 149ILE A 185PHE A 108 | None | 1.29A | 4r38C-2jgqA:undetectable | 4r38C-2jgqA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jwy | UNCHARACTERIZEDLIPOPROTEIN YAJI (Escherichiacoli) |
PF11622(DUF3251) | 5 | ILE A 104VAL A 144LEU A 147ILE A 71PHE A 149 | None | 1.17A | 4r38C-2jwyA:undetectable | 4r38C-2jwyA:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nly | DIVERGENTPOLYSACCHARIDEDEACETYLASEHYPOTHETICAL PROTEIN (Bacillushalodurans) |
PF04748(Polysacc_deac_2) | 5 | THR A 164ILE A 37VAL A 152LEU A 130ILE A 148 | None | 1.28A | 4r38C-2nlyA:undetectable | 4r38C-2nlyA:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ooq | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE T (Homo sapiens) |
PF00102(Y_phosphatase) | 5 | ILE A1048VAL A1053LEU A1064ILE A 997PHE A1067 | B3P A 301 ( 3.7A)NoneNoneNoneNone | 1.31A | 4r38C-2ooqA:undetectable | 4r38C-2ooqA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfm | ADENYLOSUCCINATELYASE (Bacillusanthracis) |
PF00206(Lyase_1)PF10397(ADSL_C) | 5 | ILE A 114GLU A 9LEU A 282LEU A 326ILE A 235 | None | 1.25A | 4r38C-2pfmA:undetectable | 4r38C-2pfmA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pn0 | PROKARYOTICTRANSCRIPTIONELONGATION FACTORGREA/GREB (Nitrosomonaseuropaea) |
PF01272(GreA_GreB)PF14760(Rnk_N) | 5 | ILE A 7GLU A 38VAL A 95LEU A 99ILE A 89 | None | 1.31A | 4r38C-2pn0A:undetectable | 4r38C-2pn0A:21.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pr5 | BLUE-LIGHTPHOTORECEPTOR (Bacillussubtilis) |
PF13426(PAS_9) | 5 | ASN A 61LEU A 65VAL A 75ILE A 92PHE A 119 | FMN A 500 (-3.2A)FMN A 500 (-4.4A)FMN A 500 (-4.6A)FMN A 500 ( 4.6A)FMN A 500 ( 4.8A) | 0.72A | 4r38C-2pr5A:17.9 | 4r38C-2pr5A:40.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q50 | GLYOXYLATEREDUCTASE/HYDROXYPYRUVATE REDUCTASE (Homo sapiens) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | THR A 103LEU A 56VAL A 63LEU A 88ILE A 78 | None | 1.20A | 4r38C-2q50A:undetectable | 4r38C-2q50A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3a | PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE3-KINASE CATALYTICSUBUNIT BETA ISOFORM (Mus musculus) |
PF00454(PI3_PI4_kinase)PF00613(PI3Ka)PF00792(PI3K_C2)PF00794(PI3K_rbd)PF02192(PI3K_p85B) | 5 | ASN A 607LEU A1000VAL A1012LEU A 541ILE A1015 | None | 1.28A | 4r38C-2y3aA:1.4 | 4r38C-2y3aA:9.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zy2 | L-ASPARTATE4-CARBOXYLYASE (Pseudomonas sp.ATCC 19121) |
PF00155(Aminotran_1_2) | 5 | GLU A 172LEU A 168VAL A 371LEU A 370ILE A 367 | None | 1.20A | 4r38C-2zy2A:undetectable | 4r38C-2zy2A:13.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahx | BETA-GLUCOSIDASE A (Clostridiumcellulovorans) |
PF00232(Glyco_hydro_1) | 5 | ILE A 93LEU A 104LEU A 150ILE A 117PHE A 86 | None | 1.32A | 4r38C-3ahxA:undetectable | 4r38C-3ahxA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 5 | ILE A 657ASN A 541LEU A 534LEU A 492ILE A 503 | None | 1.24A | 4r38C-3cemA:undetectable | 4r38C-3cemA:9.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmm | UBIQUITIN-ACTIVATINGENZYME E1 1 (Saccharomycescerevisiae) |
PF00899(ThiF)PF09358(E1_UFD)PF10585(UBA_e1_thiolCys)PF16190(E1_FCCH)PF16191(E1_4HB) | 5 | THR A 540GLU A 448LEU A 458VAL A 502ILE A 513 | None | 1.28A | 4r38C-3cmmA:undetectable | 4r38C-3cmmA:9.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cr8 | SULFATEADENYLYLTRANSFERASE,ADENYLYLSULFATEKINASE (Thiobacillusdenitrificans) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | ILE A 296ASN A 255LEU A 48LEU A 248PHE A 79 | None | 1.24A | 4r38C-3cr8A:undetectable | 4r38C-3cr8A:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eet | PUTATIVE GNTR-FAMILYTRANSCRIPTIONALREGULATOR (Streptomycesavermitilis) |
PF00392(GntR)PF07702(UTRA) | 5 | GLU A 58LEU A 49VAL A 12LEU A 16ILE A 37 | None | 0.97A | 4r38C-3eetA:undetectable | 4r38C-3eetA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gaf | 7-ALPHA-HYDROXYSTEROID DEHYDROGENASE (Brucellaabortus) |
PF13561(adh_short_C2) | 5 | ILE A 27ASN A 94VAL A 184ILE A 182PHE A 31 | None | 1.28A | 4r38C-3gafA:undetectable | 4r38C-3gafA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3goz | LEUCINE-RICHREPEAT-CONTAININGPROTEIN (Legionellapneumophila) |
no annotation | 5 | ILE A 165VAL A 113LEU A 114ILE A 111PHE A 133 | None | 1.29A | 4r38C-3gozA:undetectable | 4r38C-3gozA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7u | ALDO-KETO REDUCTASE (Arabidopsisthaliana) |
PF00248(Aldo_ket_red) | 5 | THR A 99ILE A 51LEU A 146VAL A 157LEU A 112 | None | 1.31A | 4r38C-3h7uA:undetectable | 4r38C-3h7uA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm7 | PUTATIVE4-HYDROXY-2-OXOGLUTARATE ALDOLASE /2-DEHYDRO-3-DEOXYPHOSPHOGLUCONATEALDOLASE (Yersiniaenterocolitica) |
PF07071(KDGP_aldolase) | 5 | THR A 190LEU A 17VAL A 234LEU A 237ILE A 221 | None | 1.00A | 4r38C-3lm7A:undetectable | 4r38C-3lm7A:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m0z | PUTATIVE ALDOLASE (Klebsiellapneumoniae) |
PF07071(KDGP_aldolase) | 6 | THR A 190ILE A 213LEU A 17VAL A 234LEU A 237ILE A 221 | None | 1.07A | 4r38C-3m0zA:undetectable | 4r38C-3m0zA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mux | PUTATIVE4-HYDROXY-2-OXOGLUTARATE ALDOLASE (Bacillusanthracis) |
PF07071(KDGP_aldolase) | 5 | THR A 192LEU A 18VAL A 236LEU A 239ILE A 223 | None | 0.91A | 4r38C-3muxA:undetectable | 4r38C-3muxA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2t | PUTATIVEOXIDOREDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 5 | ILE A 42LEU A 126VAL A 121LEU A 119ILE A 124 | None | 1.22A | 4r38C-3n2tA:undetectable | 4r38C-3n2tA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n3u | ADENOSINEMONOPHOSPHATE-PROTEIN TRANSFERASE IBPA (Histophilussomni) |
PF02661(Fic) | 5 | LEU A3502VAL A3584LEU A3775ILE A3580PHE A3743 | None | 1.23A | 4r38C-3n3uA:undetectable | 4r38C-3n3uA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzq | BIOSYNTHETICARGININEDECARBOXYLASE (Escherichiacoli) |
PF02784(Orn_Arg_deC_N) | 5 | ILE A 358VAL A 158LEU A 147ILE A 135PHE A 121 | None | 1.22A | 4r38C-3nzqA:undetectable | 4r38C-3nzqA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzr | 2-DEHYDRO-3-DEOXYPHOSPHOGLUCONATEALDOLASE (Aliivibriofischeri) |
PF07071(KDGP_aldolase) | 6 | THR A 190ILE A 213LEU A 17VAL A 234LEU A 237ILE A 221 | None | 1.07A | 4r38C-3nzrA:undetectable | 4r38C-3nzrA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdw | UNCHARACTERIZEDHYDROLASE YUTF (Bacillussubtilis) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 5 | THR A 198LEU A 42VAL A 31LEU A 34ILE A 11 | None | 1.08A | 4r38C-3pdwA:undetectable | 4r38C-3pdwA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rab | PROTEIN (RAB3A) (Rattusnorvegicus) |
PF00071(Ras) | 5 | ILE A 71LEU A 39LEU A 179ILE A 99PHE A 23 | ILE A 71 ( 0.7A)LEU A 39 ( 0.6A)LEU A 179 ( 0.6A)ILE A 99 ( 0.7A)PHE A 23 ( 1.3A) | 0.94A | 4r38C-3rabA:undetectable | 4r38C-3rabA:25.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rza | TRIPEPTIDASE (Staphylococcusaureus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 371LEU A 360VAL A 121LEU A 366ILE A 2 | None | 1.31A | 4r38C-3rzaA:undetectable | 4r38C-3rzaA:15.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t50 | BLUE-LIGHT-ACTIVATEDHISTIDINE KINASE (Brucellamelitensis) |
PF13426(PAS_9) | 5 | ASN A 68LEU A 72VAL A 82ILE A 99PHE A 128 | FMN A 200 (-3.1A)FMN A 200 (-4.3A)FMN A 200 (-4.3A)FMN A 200 ( 4.4A)FMN A 200 (-4.5A) | 0.78A | 4r38C-3t50A:19.9 | 4r38C-3t50A:34.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbh | O-ACETYL SERINESULFHYDRYLASE (Leishmaniadonovani) |
PF00291(PALP) | 5 | THR A 259ILE A 228VAL A 208LEU A 249ILE A 285 | None | 1.22A | 4r38C-3tbhA:undetectable | 4r38C-3tbhA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3udb | SERINE/THREONINE-PROTEIN KINASE SRK2E (Arabidopsisthaliana) |
PF00069(Pkinase) | 5 | ILE A 246GLU A 114LEU A 124LEU A 253ILE A 271 | None | 1.09A | 4r38C-3udbA:undetectable | 4r38C-3udbA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujg | SERINE/THREONINE-PROTEIN KINASE SRK2E (Arabidopsisthaliana) |
PF00069(Pkinase) | 5 | ILE A 246GLU A 114LEU A 124LEU A 253ILE A 271 | None | 1.10A | 4r38C-3ujgA:undetectable | 4r38C-3ujgA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0t | PUP--PROTEIN LIGASE (Corynebacteriumglutamicum) |
PF03136(Pup_ligase) | 5 | THR A 206GLU A 131VAL A 244LEU A 245ILE A 248 | None | 1.17A | 4r38C-4b0tA:undetectable | 4r38C-4b0tA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ex4 | MALATE SYNTHASE G (Mycobacteriumleprae) |
PF01274(Malate_synthase) | 5 | THR A 110ILE A 516LEU A 336VAL A 401PHE A 510 | None | 1.14A | 4r38C-4ex4A:undetectable | 4r38C-4ex4A:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga7 | LEUKOCYTE ELASTASEINHIBITOR (Homo sapiens) |
PF00079(Serpin) | 5 | THR A 251ILE A 370VAL A 216LEU A 231ILE A 209 | None | 1.32A | 4r38C-4ga7A:undetectable | 4r38C-4ga7A:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gcz | BLUE-LIGHTPHOTORECEPTOR,SENSOR PROTEIN FIXL (Bacillussubtilis;Bradyrhizobiumdiazoefficiens) |
PF00512(HisKA)PF02518(HATPase_c)PF13426(PAS_9) | 5 | ASN A 61LEU A 65VAL A 75ILE A 92PHE A 119 | FMN A 401 (-3.1A)FMN A 401 (-4.5A)FMN A 401 ( 4.6A)FMN A 401 ( 4.6A)FMN A 401 (-4.7A) | 0.81A | 4r38C-4gczA:18.3 | 4r38C-4gczA:25.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imr | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 5 | ILE A 27LEU A 126VAL A 88LEU A 15ILE A 79 | None | 1.26A | 4r38C-4imrA:undetectable | 4r38C-4imrA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4isa | UDP-3-O-[3-HYDROXYMYRISTOYL]N-ACETYLGLUCOSAMINEDEACETYLASE (Escherichiacoli) |
PF03331(LpxC) | 5 | ILE A 244ASN A 253LEU A 87ILE A 120PHE A 182 | NoneFMT A 420 (-3.7A)NoneNoneNone | 1.26A | 4r38C-4isaA:undetectable | 4r38C-4isaA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ivi | CARBOXYLESTERASE (unculturedbacterium) |
PF00144(Beta-lactamase) | 5 | THR A 159ILE A 224VAL A 209LEU A 208PHE A 132 | None | 1.29A | 4r38C-4iviA:undetectable | 4r38C-4iviA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jdy | PYRIDOXALBIOSYNTHESIS LYASEPDXS (Mycobacteriumtuberculosis) |
PF01680(SOR_SNZ) | 5 | ILE A 121LEU A 50LEU A 98ILE A 72PHE A 130 | None | 1.25A | 4r38C-4jdyA:undetectable | 4r38C-4jdyA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhm | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME, C-TERMINALDOMAIN PROTEIN (Pseudovibriosp. JE062) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 11VAL A 363LEU A 14ILE A 37PHE A 60 | None | 1.16A | 4r38C-4jhmA:undetectable | 4r38C-4jhmA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jkl | BETA-GLUCURONIDASE (Streptococcusagalactiae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 5 | ILE A 442GLU A 408ASN A 407LEU A 136PHE A 357 | None | 1.28A | 4r38C-4jklA:undetectable | 4r38C-4jklA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3z | D-ERYTHRULOSE4-PHOSPHATEDEHYDROGENASE (Brucellamelitensis) |
no annotation | 5 | THR A 38ILE A 225GLU A 269VAL A 294ILE A 290 | None | 1.34A | 4r38C-4k3zA:undetectable | 4r38C-4k3zA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2e | PHOSPHATIDATECYTIDYLYLTRANSFERASE (Thermotogamaritima) |
PF01148(CTP_transf_1) | 5 | ILE A 49LEU A 58VAL A 134LEU A 138ILE A 268 | None | 1.35A | 4r38C-4q2eA:undetectable | 4r38C-4q2eA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q7l | UNCHARACTERIZED ABCTRANSPORTERATP-BINDING PROTEINTM_0288 (Thermotogamaritima) |
PF00005(ABC_tran) | 5 | ILE A 422LEU A 513VAL A 398LEU A 401ILE A 544 | None | 1.21A | 4r38C-4q7lA:undetectable | 4r38C-4q7lA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASE (Thermococcuskodakarensis) |
PF00562(RNA_pol_Rpb2_6)PF00623(RNA_pol_Rpb1_2)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | THR A 667GLU B 972LEU B 928VAL B 991ILE B 992 | None | 1.28A | 4r38C-4qiwA:undetectable | 4r38C-4qiwA:10.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r3a | BLUE-LIGHT-ACTIVATEDHISTIDINE KINASE 2 (Erythrobacterlitoralis) |
PF07568(HisKA_2)PF13426(PAS_9)PF13581(HATPase_c_2) | 9 | THR A 21ILE A 25GLU A 30ASN A 54LEU A 58VAL A 68LEU A 71ILE A 85PHE A 114 | RBF A 402 (-3.4A)NoneNoneRBF A 402 (-2.9A)RBF A 402 (-4.2A)RBF A 402 (-3.5A)RBF A 402 (-3.6A)RBF A 402 (-4.0A)RBF A 402 ( 4.3A) | 0.48A | 4r38C-4r3aA:16.9 | 4r38C-4r3aA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9p | RE28239P (Drosophilamelanogaster) |
PF03166(MH2) | 5 | ILE A 153LEU A 232VAL A 224LEU A 202ILE A 42 | None | 1.18A | 4r38C-4r9pA:undetectable | 4r38C-4r9pA:20.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wuj | GLYCOSIDE HYDROLASEFAMILY 15, CELLULOSESIGNALING ASSOCIATEDPROTEIN ENVOY (Trichodermareesei) |
PF13426(PAS_9) | 6 | THR A 101ILE A 105ASN A 134LEU A 138VAL A 154ILE A 171 | FMN A5201 (-3.4A)NoneFMN A5201 (-2.5A)FMN A5201 (-3.7A)FMN A5201 (-3.6A)FMN A5201 ( 4.4A) | 0.78A | 4r38C-4wujA:15.4 | 4r38C-4wujA:33.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxz | PYRIDOXALBIOSYNTHESIS LYASEPDXS (Geobacilluskaustophilus) |
PF01680(SOR_SNZ) | 5 | ILE A 116LEU A 45LEU A 93ILE A 67PHE A 125 | NoneL5P A 81 ( 4.8A)NoneNoneNone | 1.32A | 4r38C-4wxzA:undetectable | 4r38C-4wxzA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yx8 | DSBA-LIKE PROTEIN (Proteusmirabilis) |
PF13462(Thioredoxin_4) | 5 | ILE A 201LEU A 93VAL A 106LEU A 76ILE A 97 | None | 1.26A | 4r38C-4yx8A:undetectable | 4r38C-4yx8A:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z9x | GLUCONATE5-DEHYDROGENASE (Streptococcuspyogenes) |
PF13561(adh_short_C2) | 5 | ILE A 123ASN A 92LEU A 129ILE A 181PHE A 122 | None | 1.34A | 4r38C-4z9xA:undetectable | 4r38C-4z9xA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5az3 | ABC-TYPETRANSPORTER,PERIPLASMICCOMPONENT (Corynebacteriumglutamicum) |
PF01497(Peripla_BP_2) | 5 | ILE A 316LEU A 278LEU A 289ILE A 275PHE A 294 | None | 1.28A | 4r38C-5az3A:undetectable | 4r38C-5az3A:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5buo | AMYLOID BETA A4PROTEIN (Homo sapiens) |
PF12925(APP_E2) | 5 | ILE A 451LEU A 390VAL A 461ILE A 462PHE A 437 | SCN A 714 ( 3.9A)NoneGOL A 709 ( 4.9A)NoneNone | 1.23A | 4r38C-5buoA:undetectable | 4r38C-5buoA:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c3u | L-SERINEAMMONIA-LYASE (Rhizomucormiehei) |
PF00291(PALP) | 5 | ILE A 317GLU A 279VAL A 82LEU A 83ILE A 112 | NonePLP A 401 ( 4.0A)NoneNoneNone | 1.34A | 4r38C-5c3uA:undetectable | 4r38C-5c3uA:16.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dzv | PROTEIN PCDHA7 (Mus musculus) |
PF00028(Cadherin)PF08266(Cadherin_2) | 5 | GLU A 147ASN A 146LEU A 165LEU A 171ILE A 113 | None | 1.19A | 4r38C-5dzvA:undetectable | 4r38C-5dzvA:14.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fg3 | PROBABLE TRANSLATIONINITIATION FACTORIF-2 (Aeropyrumpernix) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF11987(IF-2)PF14578(GTP_EFTU_D4) | 5 | ILE A 74LEU A 231VAL A 79LEU A 78ILE A 80 | None | 1.27A | 4r38C-5fg3A:undetectable | 4r38C-5fg3A:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdh | TOLL-LIKE RECEPTOR 8 (Homo sapiens) |
PF13855(LRR_8) | 5 | ILE A 403GLU A 427LEU A 486LEU A 474ILE A 422 | None | 1.31A | 4r38C-5hdhA:undetectable | 4r38C-5hdhA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvn | 3-DEHYDROQUINATESYNTHASE (Francisellatularensis) |
PF01761(DHQ_synthase) | 5 | THR A 143ILE A 107VAL A 98LEU A 99ILE A 122 | None | 1.31A | 4r38C-5hvnA:undetectable | 4r38C-5hvnA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hy7 | PUTATIVE PRE-MRNASPLICING PROTEIN (Chaetomiumthermophilum) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | THR A 19ILE A1118LEU A 458VAL A1114ILE A 15 | None | 1.34A | 4r38C-5hy7A:undetectable | 4r38C-5hy7A:8.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i4c | TRANSCRIPTIONALREGULATORY PROTEINRCSB (Escherichiacoli) |
PF00072(Response_reg) | 5 | GLU A 104LEU A 70VAL A 98LEU A 101ILE A 68 | None | 1.19A | 4r38C-5i4cA:undetectable | 4r38C-5i4cA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5id4 | DSBA-LIKE PROTEIN (Proteusmirabilis) |
PF13462(Thioredoxin_4) | 5 | ILE A 201LEU A 93VAL A 106LEU A 76ILE A 97 | None | 1.07A | 4r38C-5id4A:undetectable | 4r38C-5id4A:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jif | HEMAGGLUTININ-ESTERASE (Murinecoronavirus) |
PF02710(Hema_HEFG)PF03996(Hema_esterase) | 5 | THR A 277ILE A 152LEU A 260ILE A 258PHE A 200 | NA A 801 ( 4.1A)NoneNoneNoneNone | 1.27A | 4r38C-5jifA:undetectable | 4r38C-5jifA:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mji | BRAMP DOMAIN PROTEIN (Streptomycesdavaonensis) |
PF03358(FMN_red) | 5 | THR A 196LEU A 130VAL A 145LEU A 149ILE A 87 | None | 1.26A | 4r38C-5mjiA:undetectable | 4r38C-5mjiA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nkz | PEROXIN 22 (Ogataea angusta) |
no annotation | 5 | ILE D 123LEU D 81VAL D 115LEU D 119ILE D 104 | None | 1.28A | 4r38C-5nkzD:undetectable | 4r38C-5nkzD:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4h | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 5 | THR A 388ILE A 393LEU A 361ILE A 245PHE A 4 | None | 1.28A | 4r38C-5u4hA:undetectable | 4r38C-5u4hA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u9p | GLUCONATE5-DEHYDROGENASE (Burkholderiacenocepacia) |
PF13561(adh_short_C2) | 5 | ILE A 144ASN A 96LEU A 198VAL A 224LEU A 227 | NoneNAP A 301 (-3.3A)NAP A 301 ( 3.5A)NoneNone | 1.11A | 4r38C-5u9pA:undetectable | 4r38C-5u9pA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vxv | PEROXISOMAL MEMBRANEPROTEIN PEX15 (Saccharomycescerevisiae) |
no annotation | 5 | ILE A 135VAL A 184LEU A 187ILE A 237PHE A 170 | None | 1.33A | 4r38C-5vxvA:undetectable | 4r38C-5vxvA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wax | - (-) |
no annotation | 5 | ILE A 238GLU A 106LEU A 116LEU A 245ILE A 263 | None | 1.19A | 4r38C-5waxA:undetectable | 4r38C-5waxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wxu | 11S GLOBULIN (Wrightiatinctoria) |
no annotation | 5 | GLU A 66LEU A 75VAL A 182LEU A 181ILE A 183 | None | 1.33A | 4r38C-5wxuA:undetectable | 4r38C-5wxuA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xd7 | 3,6-ANHYDRO-ALPHA-L-GALACTONATECYCLOISOMERASE (Vibrio sp. EJY3) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | THR A 37GLU A 351LEU A 112ILE A 280PHE A 352 | None | 1.30A | 4r38C-5xd7A:undetectable | 4r38C-5xd7A:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z03 | MUREIN TETRAPEPTIDECARBOXYPEPTIDASE (Escherichiacoli) |
no annotation | 5 | ILE A 39ASN A 35LEU A 3LEU A 71ILE A 69 | None | 1.22A | 4r38C-5z03A:undetectable | 4r38C-5z03A:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zqz | TRIFUNCTIONAL ENZYMESUBUNIT ALPHA,MITOCHONDRIAL (Homo sapiens) |
no annotation | 5 | THR A 167LEU A 221VAL A 243LEU A 240ILE A 160 | None | 1.24A | 4r38C-5zqzA:undetectable | 4r38C-5zqzA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6axe | MALATE SYNTHASE G (Mycobacteriummarinum) |
PF01274(Malate_synthase) | 5 | THR A 110ILE A 515LEU A 335VAL A 400PHE A 509 | None | 1.15A | 4r38C-6axeA:undetectable | 4r38C-6axeA:11.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 5 | ILE A1657LEU A1862VAL A2038LEU A2037ILE A1864 | None | 1.10A | 4r38C-6bq1A:undetectable | 4r38C-6bq1A:0.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bql | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 2 (Homo sapiens) |
no annotation | 5 | ILE A 415GLU A 286LEU A 296LEU A 422ILE A 440 | None | 1.02A | 4r38C-6bqlA:undetectable | 4r38C-6bqlA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c0d | AMIDASE,HYDANTOINASE/CARBAMOYLASE FAMILY (Paraburkholderiaphymatum) |
no annotation | 5 | ILE A 78LEU A 345VAL A 204LEU A 373ILE A 202 | None | 1.26A | 4r38C-6c0dA:undetectable | 4r38C-6c0dA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT BMONOVALENT CATION/H+ANTIPORTER SUBUNIT EMONOVALENT CATION/H+ANTIPORTER SUBUNIT F (Pyrococcusfuriosus) |
no annotation | 5 | ILE F 17LEU A 17VAL B 63LEU B 66ILE B 62 | None | 1.34A | 4r38C-6cfwF:undetectable | 4r38C-6cfwF:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d46 | BETA SLIDING CLAMP (Rickettsiatyphi) |
no annotation | 5 | ILE A 182LEU A 220VAL A 193LEU A 160ILE A 226 | None | 1.34A | 4r38C-6d46A:undetectable | 4r38C-6d46A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emk | SERINE/THREONINE-PROTEIN KINASE TOR2 (Saccharomycescerevisiae) |
no annotation | 5 | ILE A2161ASN A2341LEU A2451LEU A2263ILE A2331 | None | 1.29A | 4r38C-6emkA:undetectable | 4r38C-6emkA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eo2 | TRANSCRIPTIONALREGULATORY PROTEINRCSB (Salmonellaenterica) |
no annotation | 5 | GLU A 104LEU A 70VAL A 98LEU A 101ILE A 68 | None | 1.28A | 4r38C-6eo2A:undetectable | 4r38C-6eo2A:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbv | PUTATIVE BLUE-LIGHTPHOTORECEPTOR (Dinoroseobactershibae) |
no annotation | 5 | ASN A 71LEU A 75VAL A 85ILE A 102PHE A 131 | FMN A 500 ( 3.2A)FMN A 500 (-4.0A)FMN A 500 (-4.3A)FMN A 500 ( 4.3A)FMN A 500 (-4.8A) | 0.79A | 4r38C-6gbvA:18.5 | 4r38C-6gbvA:undetectable |