SIMILAR PATTERNS OF AMINO ACIDS FOR 4R38_B_RBFB201_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b47 CBL

(Homo sapiens) 		PF02262
(Cbl_N)
PF02761
(Cbl_N2)
PF02762
(Cbl_N3) 		4 GLU A  57
LEU A  88
LEU A  95
MET A 119
 None
 0.95A 4r38B-1b47A:
1.5		 4r38B-1b47A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bdg HEXOKINASE

(Schistosoma
mansoni) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		5 THR A 353
GLU A 364
LEU A 361
VAL A 314
LEU A 319
 None
 1.36A 4r38B-1bdgA:
0.0		 4r38B-1bdgA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1by8 PROTEIN
(PROCATHEPSIN K)

(Homo sapiens) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		5 THR A 141
LEU A 145
VAL A 130
LEU A 133
MET A 314
 None
 1.32A 4r38B-1by8A:
0.0		 4r38B-1by8A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cii COLICIN IA

(Escherichia
coli) 		PF01024
(Colicin)
PF11504
(Colicin_Ia) 		4 THR A 608
ILE A 575
LEU A 591
LEU A 539
 None
 0.84A 4r38B-1ciiA:
0.0		 4r38B-1ciiA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1clw TAILSPIKE PROTEIN

(Salmonella
virus P22) 		PF09251
(PhageP22-tail) 		4 THR A 482
ILE A 477
LEU A 437
VAL A 386
 None
 0.97A 4r38B-1clwA:
2.1		 4r38B-1clwA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8k GENERAL
TRANSCRIPTION FACTOR
TFIIE-BETA

(Homo sapiens) 		PF02186
(TFIIE_beta) 		4 THR A  41
GLU A  36
LEU A  54
MET A  20
 None
 0.97A 4r38B-1d8kA:
undetectable		 4r38B-1d8kA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8k GENERAL
TRANSCRIPTION FACTOR
TFIIE-BETA

(Homo sapiens) 		PF02186
(TFIIE_beta) 		4 THR A  41
LEU A  54
VAL A  67
MET A  20
 None
 0.83A 4r38B-1d8kA:
undetectable		 4r38B-1d8kA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5d RUBREDOXIN:OXYGEN
OXIDOREDUCTASE

(Desulfovibrio
gigas) 		PF00258
(Flavodoxin_1)
PF00753
(Lactamase_B) 		4 ILE A 166
LEU A  12
VAL A 160
PHE A 167
 None
 0.97A 4r38B-1e5dA:
0.0		 4r38B-1e5dA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f7c RHOGAP PROTEIN

(Gallus gallus) 		PF00620
(RhoGAP) 		4 GLU A 306
LEU A 315
VAL A 301
LEU A 304
 None
 0.86A 4r38B-1f7cA:
undetectable		 4r38B-1f7cA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnn CELL DIVISION
CONTROL PROTEIN 6

(Pyrobaculum
aerophilum) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		4 ILE A 277
GLU A 370
VAL A 273
LEU A 274
 None
 0.95A 4r38B-1fnnA:
0.0		 4r38B-1fnnA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 THR A 453
ILE A 440
LEU A 182
PHE A 160
 None
 0.99A 4r38B-1g8kA:
0.0		 4r38B-1g8kA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl6 ATPASE

(Escherichia
coli) 		PF10412
(TrwB_AAD_bind) 		4 ILE A 173
LEU A 325
VAL A 333
PHE A 299
 None
 0.93A 4r38B-1gl6A:
undetectable		 4r38B-1gl6A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h54 MALTOSE
PHOSPHORYLASE

(Lactobacillus
brevis) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 ILE A  88
GLU A  43
LEU A 293
VAL A 119
 None
 0.97A 4r38B-1h54A:
1.4		 4r38B-1h54A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hdi PHOSPHOGLYCERATE
KINASE

(Sus scrofa) 		PF00162
(PGK) 		4 ILE A 252
LEU A 268
LEU A 281
PHE A 241
 None
 1.02A 4r38B-1hdiA:
undetectable		 4r38B-1hdiA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE

(Mycobacterium
tuberculosis) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 THR A 202
ILE A 154
VAL A 120
LEU A 123
 None
 1.01A 4r38B-1hkwA:
undetectable		 4r38B-1hkwA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jcn INOSINE
MONOPHOSPHATE
DEHYDROGENASE I

(Homo sapiens) 		PF00478
(IMPDH)
PF00571
(CBS) 		4 THR A  63
ILE A  59
VAL A 107
LEU A 244
 None
 0.96A 4r38B-1jcnA:
undetectable		 4r38B-1jcnA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1klp MEROMYCOLATE
EXTENSION ACYL
CARRIER PROTEIN

(Mycobacterium
tuberculosis) 		PF00550
(PP-binding) 		4 THR A  51
LEU A  67
VAL A  34
LEU A  37
 None
 0.91A 4r38B-1klpA:
undetectable		 4r38B-1klpA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kng THIOL:DISULFIDE
INTERCHANGE PROTEIN
CYCY

(Bradyrhizobium
japonicum) 		PF08534
(Redoxin) 		4 ILE A 168
LEU A 186
LEU A 172
PHE A 160
 None
 0.83A 4r38B-1kngA:
undetectable		 4r38B-1kngA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ks9 2-DEHYDROPANTOATE
2-REDUCTASE

(Escherichia
coli) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 THR A  70
ILE A 139
LEU A  16
LEU A 160
 None
 0.94A 4r38B-1ks9A:
undetectable		 4r38B-1ks9A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2x CLASS B
CARBAPENEMASE BLAB-1

(Elizabethkingia
meningoseptica) 		PF00753
(Lactamase_B) 		4 ILE A 113
LEU A  48
VAL A  75
LEU A  74
 None
 0.96A 4r38B-1m2xA:
undetectable		 4r38B-1m2xA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhy METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox)
PF02964
(MeMO_Hyd_G) 		4 THR B  91
LEU B 320
VAL G  75
LEU G  78
 None
 0.93A 4r38B-1mhyB:
undetectable		 4r38B-1mhyB:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n1q DPS PROTEIN

(Brevibacillus
brevis) 		PF00210
(Ferritin) 		4 LEU A  12
VAL A  17
LEU A  60
MET A 129
 None
 0.98A 4r38B-1n1qA:
undetectable		 4r38B-1n1qA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ni6 HEME OXYGENASE 1

(Homo sapiens) 		PF01126
(Heme_oxygenase) 		4 ILE A  65
LEU A  54
VAL A 115
LEU A 118
 None
 0.99A 4r38B-1ni6A:
undetectable		 4r38B-1ni6A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nij HYPOTHETICAL PROTEIN
YJIA

(Escherichia
coli) 		PF02492
(cobW)
PF07683
(CobW_C) 		4 THR A  55
ILE A  89
VAL A  95
LEU A  94
 None
 0.93A 4r38B-1nijA:
undetectable		 4r38B-1nijA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nr6 CYTOCHROME P450 2C5

(Oryctolagus
cuniculus) 		PF00067
(p450) 		4 ILE A 485
LEU A 446
VAL A 153
LEU A 156
 None
 0.93A 4r38B-1nr6A:
undetectable		 4r38B-1nr6A:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oed ACETYLCHOLINE
RECEPTOR PROTEIN,
ALPHA CHAIN
ACETYLCHOLINE
RECEPTOR PROTEIN,
BETA CHAIN

(Torpedo
marmorata) 		PF02932
(Neur_chan_memb) 		4 GLU A 262
LEU A 253
VAL B 261
LEU B 264
 None
 0.92A 4r38B-1oedA:
undetectable		 4r38B-1oedA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ox4 IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
HISHF

(Saccharomyces
cerevisiae) 		PF00117
(GATase)
PF00977
(His_biosynth) 		4 GLU B 459
LEU B 467
VAL B 451
LEU B 454
 None
 0.99A 4r38B-1ox4B:
undetectable		 4r38B-1ox4B:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p31 UDP-N-ACETYLMURAMATE
--ALANINE LIGASE

(Haemophilus
influenzae) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 THR A 381
ILE A 423
VAL A 434
LEU A 433
 None
 0.97A 4r38B-1p31A:
undetectable		 4r38B-1p31A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qbg NAD(P)H
DEHYDROGENASE
[QUINONE] 1

(Homo sapiens) 		PF02525
(Flavodoxin_2) 		4 ILE A 192
LEU A 144
MET A  21
PHE A  17
 FAD  A 501 (-4.5A)
None
None
FAD  A 501 (-4.9A)
 0.85A 4r38B-1qbgA:
undetectable		 4r38B-1qbgA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r4k ARGONAUTE 1

(Drosophila
melanogaster) 		PF02170
(PAZ) 		4 THR A 334
ILE A 342
LEU A 313
LEU A 416
 None
 1.00A 4r38B-1r4kA:
undetectable		 4r38B-1r4kA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rcw CT610

(Chlamydia
trachomatis) 		PF03070
(TENA_THI-4) 		4 ILE A 145
LEU A  78
VAL A 135
LEU A 138
 None
 0.83A 4r38B-1rcwA:
undetectable		 4r38B-1rcwA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rg6 SECOND SPLICE
VARIANT P63

(Homo sapiens) 		PF07647
(SAM_2) 		4 LEU A  31
VAL A  11
LEU A  14
PHE A  54
 None
 1.00A 4r38B-1rg6A:
undetectable		 4r38B-1rg6A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0h VOLTAGE-GATED
CALCIUM CHANNEL
SUBUNIT BETA2A

(Rattus
norvegicus) 		PF00625
(Guanylate_kin) 		4 THR B 322
ILE B 338
LEU B 272
LEU B 334
 None
 1.01A 4r38B-1t0hB:
undetectable		 4r38B-1t0hB:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1u CHOLINE
O-ACETYLTRANSFERASE

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 THR A 477
LEU A 438
VAL A 443
LEU A 442
 None
 0.89A 4r38B-1t1uA:
undetectable		 4r38B-1t1uA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tba TRANSCRIPTION
INITIATION FACTOR
TFIID

(Saccharomyces
cerevisiae) 		PF00352
(TBP) 		4 ILE B 146
LEU B 114
LEU B  82
PHE B 148
 None
 1.01A 4r38B-1tbaB:
undetectable		 4r38B-1tbaB:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tbu PEROXISOMAL
ACYL-COENZYME A
THIOESTER HYDROLASE
1

(Saccharomyces
cerevisiae) 		PF13622
(4HBT_3) 		4 THR A  40
ILE A  14
VAL A  18
LEU A  17
 None
 1.01A 4r38B-1tbuA:
undetectable		 4r38B-1tbuA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tcd TRIOSEPHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF00121
(TIM) 		5 THR A  28
ILE A 246
GLU A 242
LEU A 239
PHE A 243
 None
 1.41A 4r38B-1tcdA:
undetectable		 4r38B-1tcdA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkp IRON-RICH
DPSA-HOMOLOG PROTEIN

(Halobacterium
salinarum) 		PF00210
(Ferritin) 		4 LEU A  20
VAL A  31
LEU A  34
MET A 151
 None
 1.01A 4r38B-1tkpA:
undetectable		 4r38B-1tkpA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txz HYPOTHETICAL 32.1
KDA PROTEIN IN
ADH3-RCA1 INTERGENIC
REGION

(Saccharomyces
cerevisiae) 		PF14519
(Macro_2) 		4 THR A 195
LEU A  31
LEU A  21
PHE A  89
 APR  A 285 (-3.6A)
None
None
APR  A 285 ( 4.9A)
 0.98A 4r38B-1txzA:
undetectable		 4r38B-1txzA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz9 MANNONATE
DEHYDRATASE

(Enterococcus
faecalis) 		PF03786
(UxuA) 		4 ILE A 194
LEU A 228
VAL A 183
LEU A 186
 None
 1.00A 4r38B-1tz9A:
undetectable		 4r38B-1tz9A:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uz8 IGG FAB (IGG3,
KAPPA) HEAVY CHAIN
291-2G3-A

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ILE B  48
LEU B 109
MET B  82
PHE B  67
 None
 0.91A 4r38B-1uz8B:
undetectable		 4r38B-1uz8B:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4v UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Thermus
thermophilus) 		PF02350
(Epimerase_2) 		4 THR A 177
GLU A  17
VAL A  38
LEU A  10
 None
 1.01A 4r38B-1v4vA:
undetectable		 4r38B-1v4vA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpx PROTEIN
(TRANSALDOLASE (EC
2.2.1.2))

(Thermotoga
maritima) 		PF00923
(TAL_FSA) 		4 THR A  27
ILE A 161
LEU A  73
PHE A   4
 None
 0.87A 4r38B-1vpxA:
undetectable		 4r38B-1vpxA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vyt CALCIUM CHANNEL
BETA-3 SUBUNIT

(Rattus
norvegicus) 		PF00625
(Guanylate_kin)
PF12052
(VGCC_beta4Aa_N) 		4 THR A 273
ILE A 289
LEU A 223
LEU A 285
 None
 0.98A 4r38B-1vytA:
undetectable		 4r38B-1vytA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyr RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 6

(Homo sapiens) 		PF00307
(CH) 		4 ILE A  28
LEU A 108
LEU A  15
PHE A  34
 None
 0.96A 4r38B-1wyrA:
undetectable		 4r38B-1wyrA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x7f OUTER SURFACE
PROTEIN

(Bacillus cereus) 		PF05913
(DUF871) 		4 ILE A  96
LEU A   9
LEU A  38
PHE A  88
 None
 0.99A 4r38B-1x7fA:
undetectable		 4r38B-1x7fA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdz METHYLTRANSFERASE
GIDB

(Bacillus
subtilis) 		PF02527
(GidB) 		4 THR A 221
ILE A 218
LEU A 162
VAL A 170
 None
 0.99A 4r38B-1xdzA:
undetectable		 4r38B-1xdzA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbd RABPHILIN-3A

(Rattus
norvegicus) 		PF00071
(Ras) 		4 ILE A  71
LEU A  39
LEU A 179
PHE A  23
 None
 0.97A 4r38B-1zbdA:
undetectable		 4r38B-1zbdA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zup HYPOTHETICAL PROTEIN
TM1739

(Thermotoga
maritima) 		PF09376
(NurA) 		4 ILE A  64
LEU A 134
VAL A  99
PHE A 106
 None
 1.02A 4r38B-1zupA:
undetectable		 4r38B-1zupA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7n L(+)-MANDELATE
DEHYDROGENASE

(Pseudomonas
putida;
Spinacia
oleracea) 		PF01070
(FMN_dh) 		4 THR A 148
LEU A 107
VAL A 154
LEU A 153
 None
 0.86A 4r38B-2a7nA:
undetectable		 4r38B-2a7nA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a81 CARB

(Pectobacterium
carotovorum) 		PF00378
(ECH_1) 		4 THR A 148
ILE A 215
VAL A  83
MET A 115
 None
None
BCN  A 501 (-4.6A)
None
 1.02A 4r38B-2a81A:
undetectable		 4r38B-2a81A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2akp ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 ILE A  35
LEU A 185
VAL A 208
LEU A 207
 None
 0.96A 4r38B-2akpA:
undetectable		 4r38B-2akpA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amy PHOSPHOMANNOMUTASE 2

(Homo sapiens) 		PF03332
(PMM) 		4 THR A 237
ILE A  41
VAL A  52
LEU A  56
 None
 0.96A 4r38B-2amyA:
undetectable		 4r38B-2amyA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2an1 PUTATIVE KINASE

(Salmonella
enterica) 		PF01513
(NAD_kinase) 		4 THR A 183
LEU A  77
VAL A  90
LEU A 269
 THR  A 183 ( 0.8A)
LEU  A  77 ( 0.6A)
VAL  A  90 ( 0.6A)
LEU  A 269 ( 0.6A)
 0.94A 4r38B-2an1A:
undetectable		 4r38B-2an1A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anu HYPOTHETICAL PROTEIN
TM0559

(Thermotoga
maritima) 		no annotation 4 THR A  51
ILE A  46
LEU A 104
VAL A 122
 None
 0.89A 4r38B-2anuA:
undetectable		 4r38B-2anuA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 THR A 877
VAL A 715
LEU A 712
MET A 895
 BHM  A   1 (-3.0A)
None
None
None
 0.91A 4r38B-2ax9A:
undetectable		 4r38B-2ax9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2az3 NUCLEOSIDE
DIPHOSPHATE KINASE

(Halobacterium
salinarum) 		PF00334
(NDK) 		4 ILE A  22
LEU A  29
MET A  77
PHE A  75
 None
 0.99A 4r38B-2az3A:
undetectable		 4r38B-2az3A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2be3 GTP
PYROPHOSPHOKINASE

(Streptococcus
pneumoniae) 		PF04607
(RelA_SpoT) 		4 ILE A 142
LEU A 137
VAL A  16
LEU A  19
 None
 0.83A 4r38B-2be3A:
undetectable		 4r38B-2be3A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bj8 NICKEL RESPONSIVE
REGULATOR

(Pyrococcus
horikoshii) 		PF01402
(RHH_1)
PF08753
(NikR_C) 		4 ILE A  84
LEU A  98
VAL A  70
LEU A  73
 None
 0.96A 4r38B-2bj8A:
undetectable		 4r38B-2bj8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c20 UDP-GLUCOSE
4-EPIMERASE

(Bacillus
anthracis) 		PF01370
(Epimerase) 		4 ILE A 114
VAL A 227
LEU A 230
PHE A 167
 None
 0.94A 4r38B-2c20A:
undetectable		 4r38B-2c20A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg9 ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 ILE A  35
LEU A 185
VAL A 208
LEU A 207
 None
 0.97A 4r38B-2cg9A:
undetectable		 4r38B-2cg9A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ciy CHLOROPEROXIDASE

(Leptoxyphium
fumago) 		PF01328
(Peroxidase_2) 		4 THR A 134
ILE A 156
LEU A 167
PHE A 109
 None
None
BR  A 801 ( 4.1A)
HEM  A 396 (-4.5A)
 1.00A 4r38B-2ciyA:
undetectable		 4r38B-2ciyA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw5 BACTERIAL
FLUORINATING ENZYME
HOMOLOG

(Thermus
thermophilus) 		PF01887
(SAM_adeno_trans) 		4 GLU A 175
LEU A 230
VAL A 200
LEU A 254
 None
 0.97A 4r38B-2cw5A:
undetectable		 4r38B-2cw5A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyb TYROSYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF00579
(tRNA-synt_1b) 		4 GLU A  15
LEU A 252
VAL A 208
LEU A 207
 None
 0.96A 4r38B-2cybA:
undetectable		 4r38B-2cybA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyb TYROSYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF00579
(tRNA-synt_1b) 		4 GLU A  15
VAL A 208
LEU A 207
MET A  51
 None
 0.82A 4r38B-2cybA:
undetectable		 4r38B-2cybA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czd OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Pyrococcus
horikoshii) 		PF00215
(OMPdecase) 		4 ILE A  63
LEU A  99
VAL A  84
LEU A  60
 None
 0.91A 4r38B-2czdA:
undetectable		 4r38B-2czdA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dt9 ASPARTOKINASE

(Thermus
thermophilus) 		PF01842
(ACT)
PF13840
(ACT_7) 		5 ILE A 129
LEU A  12
VAL A 101
MET A 115
PHE A 116
 None
 1.18A 4r38B-2dt9A:
undetectable		 4r38B-2dt9A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dwu GLUTAMATE RACEMASE

(Bacillus
anthracis) 		PF01177
(Asp_Glu_race) 		4 THR A 215
ILE A  35
VAL A  62
LEU A  13
 None
 0.98A 4r38B-2dwuA:
undetectable		 4r38B-2dwuA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ec5 DERMONECROTIC TOXIN

(Pasteurella
multocida) 		PF11647
(MLD) 		4 ILE A 749
LEU A 780
MET A 834
PHE A 752
 None
 0.91A 4r38B-2ec5A:
undetectable		 4r38B-2ec5A:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ehh DIHYDRODIPICOLINATE
SYNTHASE

(Aquifex
aeolicus) 		PF00701
(DHDPS) 		4 ILE A 173
VAL A 202
LEU A 184
PHE A 181
 None
 0.99A 4r38B-2ehhA:
undetectable		 4r38B-2ehhA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ets HYPOTHETICAL PROTEIN

(Staphylococcus
aureus) 		PF08807
(DUF1798) 		4 GLU A  80
VAL A  98
LEU A  95
PHE A  19
 None
 0.95A 4r38B-2etsA:
undetectable		 4r38B-2etsA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fe1 CONSERVED
HYPOTHETICAL PROTEIN
PAE0151

(Pyrobaculum
aerophilum) 		PF01850
(PIN) 		4 THR A  97
LEU A  38
VAL A   4
LEU A 114
 None
 1.02A 4r38B-2fe1A:
undetectable		 4r38B-2fe1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ffs HYPOTHETICAL PROTEIN
PA1206

(Pseudomonas
aeruginosa) 		PF08982
(DUF1857) 		4 THR A 141
LEU A  94
VAL A  67
LEU A  60
 None
 0.99A 4r38B-2ffsA:
undetectable		 4r38B-2ffsA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fki PROTEIN YJBR

(Escherichia
coli) 		PF04237
(YjbR) 		4 GLU A 109
LEU A 118
VAL A 104
LEU A 107
 None
 0.79A 4r38B-2fkiA:
undetectable		 4r38B-2fkiA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gf9 RAS-RELATED PROTEIN
RAB-3D

(Homo sapiens) 		PF00071
(Ras) 		5 ILE A  71
LEU A  39
VAL A 175
LEU A 179
PHE A  23
 None
 1.21A 4r38B-2gf9A:
undetectable		 4r38B-2gf9A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gn4 UDP-GLCNAC C6
DEHYDRATASE

(Helicobacter
pylori) 		PF02719
(Polysacc_synt_2) 		5 ILE A 284
GLU A 228
LEU A 218
LEU A 302
PHE A 279
 None
 1.37A 4r38B-2gn4A:
undetectable		 4r38B-2gn4A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hcb CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA

(Aquifex
aeolicus) 		PF00308
(Bac_DnaA)
PF08299
(Bac_DnaA_C) 		4 GLU A 271
LEU A 305
VAL A 320
LEU A 324
 None
 1.01A 4r38B-2hcbA:
undetectable		 4r38B-2hcbA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus 1) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 LEU A 422
VAL A 365
LEU A 368
PHE A 389
 None
 0.97A 4r38B-2hnzA:
undetectable		 4r38B-2hnzA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inr DNA TOPOISOMERASE 4
SUBUNIT A

(Staphylococcus
aureus) 		PF00521
(DNA_topoisoIV) 		4 ILE A 209
LEU A 340
VAL A  34
LEU A 163
 None
 0.93A 4r38B-2inrA:
undetectable		 4r38B-2inrA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iu5 HTH-TYPE DHAKLM
OPERON
TRANSCRIPTIONAL
ACTIVATOR DHAS

(Lactococcus
lactis) 		PF00440
(TetR_N) 		4 ILE A 119
LEU A  82
VAL A 168
LEU A 171
 None
 0.77A 4r38B-2iu5A:
undetectable		 4r38B-2iu5A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 THR A 751
GLU A 731
LEU A 464
PHE A 728
 None
 0.92A 4r38B-2iujA:
undetectable		 4r38B-2iujA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iv8 AP-2 COMPLEX SUBUNIT
BETA-1

(Homo sapiens) 		PF02883
(Alpha_adaptinC2)
PF09066
(B2-adapt-app_C) 		4 ILE A 899
LEU A 819
VAL A 824
LEU A 825
 None
 1.02A 4r38B-2iv8A:
1.9		 4r38B-2iv8A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivx CYCLIN-T2

(Homo sapiens) 		PF00134
(Cyclin_N) 		4 GLU A 239
LEU A 230
VAL A 194
PHE A 240
 None
 1.01A 4r38B-2ivxA:
undetectable		 4r38B-2ivxA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2izo FLAP
STRUCTURE-SPECIFIC
ENDONUCLEASE

(Sulfolobus
solfataricus) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		4 ILE A 211
GLU A 210
LEU A 175
LEU A 181
 None
 0.92A 4r38B-2izoA:
undetectable		 4r38B-2izoA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nnj CYTOCHROME P450 2C8

(Homo sapiens) 		PF00067
(p450) 		4 ILE A 488
LEU A 449
VAL A 153
LEU A 156
 None
 0.82A 4r38B-2nnjA:
undetectable		 4r38B-2nnjA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nux 2-KETO-3-DEOXYGLUCON
ATE/2-KETO-3-DEOXY-6
-PHOSPHO GLUCONATE
ALDOLASE

(Sulfolobus
acidocaldarius) 		PF00701
(DHDPS) 		4 ILE A  92
LEU A  49
VAL A  80
LEU A  83
 None
 1.02A 4r38B-2nuxA:
undetectable		 4r38B-2nuxA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nvu MALTOSE BINDING
PROTEIN/NEDD8-ACTIVA
TING ENZYME E1
CATALYTIC SUBUNIT
CHIMERA
NEDD8-CONJUGATING
ENZYME UBC12

(Homo sapiens) 		PF00179
(UQ_con)
PF00899
(ThiF)
PF08825
(E2_bind)
PF13416
(SBP_bac_8) 		4 ILE B2400
LEU C  32
VAL C  82
LEU C  58
 None
 1.00A 4r38B-2nvuB:
undetectable		 4r38B-2nvuB:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwb CONSERVED DOMAIN
PROTEIN

(Shewanella
oneidensis) 		PF08933
(DUF1864) 		4 THR A 190
ILE A 242
LEU A 287
LEU A 251
 None
HEM  A 401 (-3.7A)
None
None
 0.96A 4r38B-2nwbA:
undetectable		 4r38B-2nwbA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o26 KIT LIGAND

(Mus musculus) 		PF02404
(SCF) 		4 ILE A  15
VAL A  49
LEU A  52
PHE A 116
 None
 0.94A 4r38B-2o26A:
undetectable		 4r38B-2o26A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ong 4S-LIMONENE SYNTHASE

(Mentha spicata) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ILE A 462
LEU A 571
VAL A 491
LEU A 492
 None
 1.00A 4r38B-2ongA:
undetectable		 4r38B-2ongA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5x N-ACETYLSEROTONIN
O-METHYLTRANSFERASE-
LIKE PROTEIN

(Homo sapiens) 		PF02545
(Maf) 		5 THR A 123
ILE A 127
VAL A  37
LEU A  17
PHE A 204
 None
 1.43A 4r38B-2p5xA:
1.7		 4r38B-2p5xA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pls CBS DOMAIN PROTEIN

(Chlorobaculum
tepidum) 		PF03471
(CorC_HlyC) 		4 THR A 402
GLU A 405
VAL A 361
LEU A 364
 None
 0.87A 4r38B-2plsA:
undetectable		 4r38B-2plsA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q04 ACETOIN UTILIZATION
PROTEIN

(Exiguobacterium
sibiricum) 		PF00583
(Acetyltransf_1) 		4 ILE A  72
LEU A 116
LEU A  11
PHE A 106
 None
 0.95A 4r38B-2q04A:
undetectable		 4r38B-2q04A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qa1 POLYKETIDE OXYGENASE
PGAE

(Streptomyces
sp. PGA64) 		PF01494
(FAD_binding_3) 		4 THR A  50
ILE A 375
GLU A 374
LEU A 329
 None
 0.94A 4r38B-2qa1A:
undetectable		 4r38B-2qa1A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qh5 MANNOSE-6-PHOSPHATE
ISOMERASE

(Helicobacter
pylori) 		PF00483
(NTP_transferase) 		4 ILE A 153
VAL A 190
MET A 249
PHE A 164
 None
 0.99A 4r38B-2qh5A:
undetectable		 4r38B-2qh5A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qq6 MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 GLU A  65
LEU A  99
VAL A 108
LEU A 111
 None
 0.82A 4r38B-2qq6A:
undetectable		 4r38B-2qq6A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qve TYROSINE AMINOMUTASE

(Streptomyces
globisporus) 		PF00221
(Lyase_aromatic) 		4 GLU A 380
LEU A 471
VAL A 386
LEU A 387
 None
 0.96A 4r38B-2qveA:
undetectable		 4r38B-2qveA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvw GLP_546_48378_50642

(Giardia
intestinalis) 		PF00636
(Ribonuclease_3)
PF02170
(PAZ) 		4 ILE A 729
LEU A 662
LEU A 656
PHE A 741
 None
None
MN  A 757 ( 4.7A)
None
 0.97A 4r38B-2qvwA:
undetectable		 4r38B-2qvwA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6f EXCINUCLEASE ABC
SUBUNIT A

(Geobacillus
stearothermophilus) 		PF00005
(ABC_tran) 		4 THR A 701
ILE A 707
LEU A 814
PHE A 704
 None
 1.00A 4r38B-2r6fA:
undetectable		 4r38B-2r6fA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v25 MAJOR CELL-BINDING
FACTOR

(Campylobacter
jejuni) 		PF00497
(SBP_bac_3) 		4 ILE A 137
LEU A 109
LEU A 189
MET A 120
 None
 0.97A 4r38B-2v25A:
undetectable		 4r38B-2v25A:
21.48