SIMILAR PATTERNS OF AMINO ACIDS FOR 4R29_D_SAMD301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0i D-AMINO ACID OXIDASE

(Rhodotorula
toruloides) 		PF01266
(DAO) 		3 ARG A1288
GLU A1297
TYR A1331
 None
 0.92A 4r29D-1c0iA:
0.0		 4r29D-1c0iA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ea6 PMS1 PROTEIN HOMOLOG
2

(Homo sapiens) 		PF01119
(DNA_mis_repair)
PF13589
(HATPase_c_3) 		3 ARG A 151
GLU A  67
TYR A 149
 None
 1.00A 4r29D-1ea6A:
0.0		 4r29D-1ea6A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f5a POLY(A) POLYMERASE

(Bos taurus) 		PF01909
(NTP_transf_2)
PF04926
(PAP_RNA-bind)
PF04928
(PAP_central) 		3 ARG A  61
GLU A  55
TYR A 103
 None
 0.95A 4r29D-1f5aA:
0.0		 4r29D-1f5aA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idj PECTIN LYASE A

(Aspergillus
niger) 		PF00544
(Pec_lyase_C) 		3 ARG A 236
GLU A  86
TYR A 211
 None
 0.85A 4r29D-1idjA:
0.0		 4r29D-1idjA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ARG A 449
GLU A 392
TYR A 529
 None
 0.99A 4r29D-1kfiA:
0.0		 4r29D-1kfiA:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ltl DNA REPLICATION
INITIATOR
(CDC21/CDC54)

(Methanothermobacter
thermautotrophicus) 		PF14551
(MCM_N)
PF17207
(MCM_OB) 		3 ARG A  37
GLU A 170
TYR A  33
 None
 0.92A 4r29D-1ltlA:
0.0		 4r29D-1ltlA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lwu FIBRINOGEN BETA
CHAIN

(Petromyzon
marinus) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		3 ARG B 285
GLU B 311
TYR B 290
 None
 0.98A 4r29D-1lwuB:
0.0		 4r29D-1lwuB:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obb ALPHA-GLUCOSIDASE

(Thermotoga
maritima) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		3 ARG A 422
GLU A 391
TYR A 418
 None
 0.91A 4r29D-1obbA:
0.0		 4r29D-1obbA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p27 MAGO NASHI PROTEIN
HOMOLOG
RNA-BINDING PROTEIN
8A

(Homo sapiens;
Homo sapiens) 		PF02792
(Mago_nashi)
PF00076
(RRM_1) 		3 ARG B 109
GLU A 117
TYR A 124
 None
 0.81A 4r29D-1p27B:
undetectable		 4r29D-1p27B:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2b CYTOHESIN 3

(Mus musculus) 		PF00169
(PH) 		3 ARG A 285
GLU A 346
TYR A 296
 SO4  A 501 (-3.9A)
None
SO4  A 501 (-4.8A)
 1.00A 4r29D-1u2bA:
undetectable		 4r29D-1u2bA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfo RECEPTOR PROTEIN
TYROSINE PHOSPHATASE
ALPHA

(Mus musculus) 		PF00102
(Y_phosphatase) 		3 ARG A 261
GLU A 338
TYR A 262
 None
 1.00A 4r29D-1yfoA:
undetectable		 4r29D-1yfoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z01 2-OXO-1,2-DIHYDROQUI
NOLINE
8-MONOOXYGENASE,
OXYGENASE COMPONENT

(Pseudomonas
putida) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		3 ARG A 210
GLU A 385
TYR A  33
 None
 0.93A 4r29D-1z01A:
undetectable		 4r29D-1z01A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2atc ASPARTATE
CARBAMOYLTRANSFERASE
, CATALYTIC CHAIN

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		3 ARG A 183
GLU A 217
TYR A 185
 None
 0.95A 4r29D-2atcA:
undetectable		 4r29D-2atcA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0n A197

(Sulfolobus
turreted
icosahedral
virus 1) 		no annotation 3 ARG A 184
GLU A 105
TYR A  90
 None
 1.01A 4r29D-2c0nA:
undetectable		 4r29D-2c0nA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cgj L-RHAMNULOSE KINASE

(Escherichia
coli) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 ARG A 106
GLU A 149
TYR A  48
 None
 0.87A 4r29D-2cgjA:
undetectable		 4r29D-2cgjA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dao TRANSCRIPTION FACTOR
ETV6

(Homo sapiens) 		PF00178
(Ets) 		3 ARG A  69
GLU A 111
TYR A  72
 None
 0.94A 4r29D-2daoA:
undetectable		 4r29D-2daoA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f7l 455AA LONG
HYPOTHETICAL
PHOSPHO-SUGAR MUTASE

(Sulfurisphaera
tokodaii) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ARG A  11
GLU A 216
TYR A 103
 None
 0.98A 4r29D-2f7lA:
undetectable		 4r29D-2f7lA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fdb FIBROBLAST GROWTH
FACTOR 8 ISOFORM B

(Homo sapiens) 		PF00167
(FGF) 		3 ARG M 177
GLU M  78
TYR M  57
 None
 1.02A 4r29D-2fdbM:
undetectable		 4r29D-2fdbM:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fuv PHOSPHOGLUCOMUTASE

(Salmonella
enterica) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ARG A 447
GLU A 390
TYR A 518
 None
 0.73A 4r29D-2fuvA:
undetectable		 4r29D-2fuvA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2k METHIONINE SYNTHASE

(Homo sapiens) 		PF02965
(Met_synt_B12) 		3 ARG A1172
GLU A1140
TYR A1219
 None
 0.96A 4r29D-2o2kA:
undetectable		 4r29D-2o2kA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q9u A-TYPE FLAVOPROTEIN

(Giardia
intestinalis) 		no annotation 3 ARG A 235
GLU A  12
TYR A 225
 None
 0.94A 4r29D-2q9uA:
undetectable		 4r29D-2q9uA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qeu PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE

(Paraburkholderia
xenovorans) 		PF02627
(CMD) 		3 ARG A  49
GLU A  80
TYR A  45
 CIT  A 146 (-3.8A)
CIT  A 146 ( 3.0A)
CIT  A 146 (-4.7A)
 0.96A 4r29D-2qeuA:
undetectable		 4r29D-2qeuA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xax RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE 1
SUBUNIT ALPHA

(Escherichia
coli) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		3 ARG A  72
GLU A 671
TYR A 659
 None
 0.76A 4r29D-2xaxA:
undetectable		 4r29D-2xaxA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ysk HYPOTHETICAL PROTEIN
TTHA1432

(Thermus
thermophilus) 		PF10025
(DUF2267) 		3 ARG A  67
GLU A 126
TYR A  71
 SO4  A 146 ( 4.6A)
None
None
 0.86A 4r29D-2yskA:
undetectable		 4r29D-2yskA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a31 PROBABLE
THREONYL-TRNA
SYNTHETASE 1

(Aeropyrum
pernix) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		3 ARG A  52
GLU A  72
TYR A  53
 None
 0.87A 4r29D-3a31A:
undetectable		 4r29D-3a31A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5t MALATE DEHYDROGENASE

(Burkholderia
pseudomallei) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 ARG A 319
GLU A 277
TYR A 139
 None
 0.95A 4r29D-3d5tA:
undetectable		 4r29D-3d5tA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dlj BETA-ALA-HIS
DIPEPTIDASE

(Homo sapiens) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 ARG A 317
GLU A 279
TYR A 284
 None
 0.87A 4r29D-3dljA:
undetectable		 4r29D-3dljA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo sapiens) 		PF00104
(Hormone_recep)
PF00105
(zf-C4) 		3 ARG D 136
GLU D 129
TYR D 123
 None
 1.00A 4r29D-3dzuD:
undetectable		 4r29D-3dzuD:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eck PROTEIN
(HOMOPROTOCATECHUATE
2,3-DIOXYGENASE)

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		3 ARG A 265
GLU A 329
TYR A 257
 None
 0.93A 4r29D-3eckA:
undetectable		 4r29D-3eckA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fbs OXIDOREDUCTASE

(Agrobacterium
fabrum) 		PF07992
(Pyr_redox_2) 		3 ARG A  36
GLU A  61
TYR A  12
 None
None
FAD  A 298 (-4.7A)
 0.98A 4r29D-3fbsA:
undetectable		 4r29D-3fbsA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g77 CYTOSINE DEAMINASE

(Escherichia
coli) 		PF07969
(Amidohydro_3) 		3 ARG A 174
GLU A 166
TYR A 207
 None
 0.92A 4r29D-3g77A:
undetectable		 4r29D-3g77A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gcf TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
1,9A-DIOXYGENASE

(Nocardioides
aromaticivorans) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		3 ARG A 178
GLU A 357
TYR A  24
 None
 0.89A 4r29D-3gcfA:
undetectable		 4r29D-3gcfA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gkq TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
1,9A-DIOXYGENASE

(Sphingomonas
sp. KA1) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		3 ARG A 175
GLU A 354
TYR A  21
 None
 0.92A 4r29D-3gkqA:
undetectable		 4r29D-3gkqA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzf REPLICASE
POLYPROTEIN 1AB

(Alphacoronavirus
1) 		PF16348
(Corona_NSP4_C) 		3 ARG A  79
GLU A  27
TYR A  75
 None
 0.88A 4r29D-3gzfA:
undetectable		 4r29D-3gzfA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j04 MYOSIN-11

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		3 ARG A 733
GLU A 786
TYR A 734
 None
 0.90A 4r29D-3j04A:
undetectable		 4r29D-3j04A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jv7 ADH-A

(Rhodococcus
ruber) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ARG A 298
GLU A 303
TYR A  87
 None
 0.83A 4r29D-3jv7A:
undetectable		 4r29D-3jv7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kao TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE

(Staphylococcus
aureus) 		PF01791
(DeoC) 		3 ARG A  29
GLU A 110
TYR A  73
 SO4  A 327 (-4.6A)
None
None
 0.86A 4r29D-3kaoA:
undetectable		 4r29D-3kaoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Thermococcus
kodakarensis) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 ARG A 205
GLU A 192
TYR A 168
 None
MG  A 500 ( 2.5A)
None
 0.96A 4r29D-3kdnA:
undetectable		 4r29D-3kdnA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l91 ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ
SUBUNIT BETA

(Pseudomonas
aeruginosa) 		PF01804
(Penicil_amidase) 		3 ARG B 296
GLU B 441
TYR B 362
 None
 0.88A 4r29D-3l91B:
undetectable		 4r29D-3l91B:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc6 SPHINGOSINE-1-PHOSPH
ATE LYASE

(Saccharomyces
cerevisiae) 		PF00282
(Pyridoxal_deC) 		3 ARG C 475
GLU C 354
TYR C 476
 None
 0.96A 4r29D-3mc6C:
undetectable		 4r29D-3mc6C:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myo TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE 1

(Streptococcus
pyogenes) 		PF01791
(DeoC) 		3 ARG A  28
GLU A 109
TYR A  72
 None
 0.77A 4r29D-3myoA:
undetectable		 4r29D-3myoA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nuz PUTATIVE ACETYL
XYLAN ESTERASE

(Bacteroides
fragilis) 		PF12715
(Abhydrolase_7) 		3 ARG A 307
GLU A 200
TYR A 224
 None
 0.98A 4r29D-3nuzA:
undetectable		 4r29D-3nuzA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwz BH2602 PROTEIN

(Bacillus
halodurans) 		PF03061
(4HBT) 		3 ARG A 127
GLU A 152
TYR A 125
 None
 0.94A 4r29D-3nwzA:
undetectable		 4r29D-3nwzA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ol2 PLEXIN-B1

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI) 		3 ARG B  40
GLU B 464
TYR B 467
 None
 0.84A 4r29D-3ol2B:
undetectable		 4r29D-3ol2B:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ooi HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-36 AND H4
LYSINE-20 SPECIFIC

(Homo sapiens) 		PF00856
(SET) 		3 ARG A  88
GLU A  68
TYR A  90
 None
 0.96A 4r29D-3ooiA:
undetectable		 4r29D-3ooiA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pwv MHC CLASS I ANTIGEN

(Bos taurus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 ARG A   5
GLU A 211
TYR A 101
 None
 0.67A 4r29D-3pwvA:
undetectable		 4r29D-3pwvA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rze HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 ARG A1148
GLU A1011
TYR A1161
 None
 1.00A 4r29D-3rzeA:
undetectable		 4r29D-3rzeA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		3 ARG A  79
GLU A 265
TYR A  78
 None
 1.01A 4r29D-3vr1A:
undetectable		 4r29D-3vr1A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djh KAPPA-TYPE OPIOID
RECEPTOR, LYSOZYME

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		3 ARG A1148
GLU A1011
TYR A1161
 None
 0.87A 4r29D-4djhA:
undetectable		 4r29D-4djhA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyo ASPARTYL
AMINOPEPTIDASE

(Homo sapiens) 		PF02127
(Peptidase_M18) 		3 ARG A 380
GLU A 301
TYR A 381
 None
SD4  A 504 (-2.7A)
SD4  A 504 (-4.7A)
 1.00A 4r29D-4dyoA:
undetectable		 4r29D-4dyoA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ffl PYLC

(Methanosarcina
barkeri) 		PF02655
(ATP-grasp_3) 		3 ARG A 243
GLU A 135
TYR A  98
 PO4  A 903 (-2.8A)
None
None
 0.94A 4r29D-4fflA:
undetectable		 4r29D-4fflA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fir PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Pyrococcus
horikoshii) 		PF01680
(SOR_SNZ)
PF05690
(ThiG) 		3 ARG A 143
GLU A 109
TYR A 199
 None
 0.85A 4r29D-4firA:
undetectable		 4r29D-4firA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hjh PHOSPHOMANNOMUTASE

(Brucella
melitensis) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ARG A 445
GLU A 322
TYR A 447
 G6Q  A 544 (-4.0A)
G6Q  A 544 (-2.3A)
EDO  A 548 (-4.8A)
 0.97A 4r29D-4hjhA:
undetectable		 4r29D-4hjhA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3u ALDEHYDE
DEHYDROGENASE (NAD+)

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		3 ARG A 108
GLU A 442
TYR A 104
 POA  A 500 (-2.6A)
None
None
 0.98A 4r29D-4i3uA:
undetectable		 4r29D-4i3uA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l5t INTERFERON-ACTIVABLE
PROTEIN 202

(Mus musculus) 		PF02760
(HIN) 		3 ARG A 376
GLU A 427
TYR A 375
 None
 1.02A 4r29D-4l5tA:
undetectable		 4r29D-4l5tA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4la2 DIMETHYLSULPHONIOPRO
PIONATE (DMSP) LYASE
DDDQ

(Ruegeria
lacuscaerulensis) 		PF16867
(DMSP_lyase) 		3 ARG A  75
GLU A  81
TYR A  90
 None
 0.78A 4r29D-4la2A:
undetectable		 4r29D-4la2A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lx3 DNA POLYMERASE III,
ALPHA SUBUNIT
NUCLEIC ACID
BINDING, OB-FOLD,
TRNA/HELICASE-TYPE

(Nostoc
punctiforme;
Nostoc
punctiforme) 		no annotation
no annotation 		3 ARG B   7
GLU A  86
TYR A  58
 None
 1.02A 4r29D-4lx3B:
undetectable		 4r29D-4lx3B:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4miv N-SULPHOGLUCOSAMINE
SULPHOHYDROLASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ARG A 382
GLU A 355
TYR A 312
 None
 0.89A 4r29D-4mivA:
undetectable		 4r29D-4mivA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9n STEROL UPTAKE
CONTROL PROTEIN 2,
LYSOZYME

(Saccharomyces
cerevisiae;
Escherichia
virus T4) 		PF00959
(Phage_lysozyme)
PF11951
(Fungal_trans_2) 		3 ARG A1148
GLU A1011
TYR A1161
 None
 0.98A 4r29D-4n9nA:
undetectable		 4r29D-4n9nA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE

(Janthinobacterium
sp. J3) 		PF00355
(Rieske)
PF11723
(Aromatic_hydrox) 		3 ARG A 172
GLU A 353
TYR A  18
 None
 0.96A 4r29D-4nbgA:
undetectable		 4r29D-4nbgA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nwo MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
MOGA

(Shewanella
oneidensis) 		PF00994
(MoCF_biosynth) 		3 ARG A 173
GLU A 158
TYR A 152
 None
 0.94A 4r29D-4nwoA:
undetectable		 4r29D-4nwoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3m BLOOM SYNDROME
PROTEIN

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF00570
(HRDC)
PF09382
(RQC)
PF16124
(RecQ_Zn_bind) 		3 ARG A 859
GLU A 796
TYR A 974
 EDO  A1304 (-3.6A)
None
None
 0.94A 4r29D-4o3mA:
undetectable		 4r29D-4o3mA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r20 CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2

(Danio rerio) 		PF00067
(p450) 		3 ARG A 246
GLU A 305
TYR A 208
 None
 0.88A 4r29D-4r20A:
undetectable		 4r29D-4r20A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgk UNCHARACTERIZED
PROTEIN

(Yersinia pestis) 		PF07350
(DUF1479) 		3 ARG A 286
GLU A 310
TYR A 282
 None
 0.92A 4r29D-4rgkA:
undetectable		 4r29D-4rgkA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upi SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		3 ARG A  16
GLU A 340
TYR A 294
 None
 0.71A 4r29D-4upiA:
undetectable		 4r29D-4upiA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upl SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ARG A  12
GLU A 338
TYR A 292
 None
 0.70A 4r29D-4uplA:
undetectable		 4r29D-4uplA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wd4 HEME OXYGENASE 1

(Homo sapiens) 		PF01126
(Heme_oxygenase) 		3 ARG A  85
GLU A  81
TYR A 137
 None
 0.95A 4r29D-4wd4A:
undetectable		 4r29D-4wd4A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xey TYROSINE-PROTEIN
KINASE ABL1

(Homo sapiens) 		no annotation 3 ARG B 381
GLU B 300
TYR B 412
 None
 0.99A 4r29D-4xeyB:
undetectable		 4r29D-4xeyB:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvp BGFP-C

(synthetic
construct) 		PF02985
(HEAT)
PF03130
(HEAT_PBS)
PF13646
(HEAT_2) 		3 ARG D 140
GLU D 106
TYR D 161
 None
 1.02A 4r29D-4xvpD:
undetectable		 4r29D-4xvpD:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1k OUTER MEMBRANE
PROTEIN OPRM

(Pseudomonas
aeruginosa) 		PF02321
(OEP) 		3 ARG A  78
GLU A 147
TYR A  77
 None
 0.96A 4r29D-4y1kA:
1.1		 4r29D-4y1kA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y93 NON-SPECIFIC
PROTEIN-TYROSINE
KINASE,NON-SPECIFIC
PROTEIN-TYROSINE
KINASE

(Bos taurus) 		PF00169
(PH)
PF00779
(BTK)
PF07714
(Pkinase_Tyr) 		3 ARG A 615
GLU A 640
TYR A 631
 None
 0.85A 4r29D-4y93A:
undetectable		 4r29D-4y93A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bug PHOSPHATIDYLINOSITOL
3,4,5-TRISPHOSPHATE
3-PHOSPHATASE AND
DUAL-SPECIFICITY
PROTEIN PHOSPHATASE
PTEN

(Homo sapiens) 		PF00782
(DSPc)
PF10409
(PTEN_C2) 		3 ARG A 161
GLU A 157
TYR A  16
 None
 0.99A 4r29D-5bugA:
undetectable		 4r29D-5bugA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5crj TRANSCRIPTION
TERMINATION FACTOR
1, MITOCHONDRIAL

(Homo sapiens) 		PF02536
(mTERF) 		3 ARG O 350
GLU O 280
TYR O 317
 None
 0.95A 4r29D-5crjO:
undetectable		 4r29D-5crjO:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Acinetobacter
baumannii) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 108
GLU A  90
TYR A 472
 None
 1.00A 4r29D-5fr8A:
undetectable		 4r29D-5fr8A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h3w FIBRONECTIN/FIBRINOG
EN BINDING PROTEIN

(Streptococcus
suis) 		PF05670
(DUF814)
PF05833
(FbpA) 		3 ARG A  45
GLU A  39
TYR A  97
 None
 1.01A 4r29D-5h3wA:
undetectable		 4r29D-5h3wA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb4 NUP192,NUCLEOPORIN
NUP192

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		3 ARG B 304
GLU B 355
TYR B 340
 None
 0.72A 4r29D-5hb4B:
undetectable		 4r29D-5hb4B:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hcc COMPLEMENT C5
COMPLEMENT C5

(Homo sapiens;
Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF01835
(A2M_N)
PF07703
(A2M_N_2) 		3 ARG A 766
GLU A1436
TYR B 222
 None
 0.91A 4r29D-5hccA:
undetectable		 4r29D-5hccA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		3 ARG A 630
GLU A 578
TYR A 631
 None
 0.98A 4r29D-5hdhA:
undetectable		 4r29D-5hdhA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hpk E3 UBIQUITIN-PROTEIN
LIGASE NEDD4-LIKE
UBIQUITIN VARIANT
NL.1

(Homo sapiens;
Homo sapiens) 		PF00632
(HECT)
PF00240
(ubiquitin) 		3 ARG B   6
GLU A 664
TYR B  68
 None
 0.63A 4r29D-5hpkB:
undetectable		 4r29D-5hpkB:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz3 PREDICTED PROTEIN

(Physcomitrella
patens) 		PF00316
(FBPase) 		3 ARG B 374
GLU B 258
TYR B 283
 None
 0.96A 4r29D-5iz3B:
undetectable		 4r29D-5iz3B:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jir OOP FAMILY OMPA-OMPF
PORIN

(Treponema
pallidum) 		no annotation 3 ARG B 468
GLU B 214
TYR B 368
 None
 0.87A 4r29D-5jirB:
undetectable		 4r29D-5jirB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jx5 GLUCANASE

(Orpinomyces sp.
Y102) 		PF01341
(Glyco_hydro_6) 		3 ARG A 185
GLU A 146
TYR A 186
 None
 0.90A 4r29D-5jx5A:
undetectable		 4r29D-5jx5A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jzb 4,5:9,10-DISECO-3-HY
DROXY-5,9,17-TRIOXOA
NDROSTA-1(10),2-DIEN
E-4-OATE HYDROLASE

(Mycobacterium
tuberculosis) 		PF12697
(Abhydrolase_6) 		3 ARG A 228
GLU A 218
TYR A 227
 None
 0.88A 4r29D-5jzbA:
undetectable		 4r29D-5jzbA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5knn ALANINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		PF01411
(tRNA-synt_2c) 		3 ARG A 326
GLU A 442
TYR A 322
 None
 0.94A 4r29D-5knnA:
undetectable		 4r29D-5knnA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkd GLUTATHIONE
S-TRANSFERASE
OMEGA-LIKE 2

(Saccharomyces
cerevisiae) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		3 ARG A  15
GLU A 238
TYR A 216
 GSH  A 401 (-4.0A)
None
None
 1.01A 4r29D-5lkdA:
undetectable		 4r29D-5lkdA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lsu HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2

(Homo sapiens) 		PF00856
(SET) 		3 ARG A1060
GLU A1040
TYR A1062
 None
 0.89A 4r29D-5lsuA:
undetectable		 4r29D-5lsuA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me4 PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN HTXB

(Pseudomonas
stutzeri) 		no annotation 3 ARG A 178
GLU A  28
TYR A  91
 HP4  A 301 ( 4.0A)
None
None
 0.96A 4r29D-5me4A:
undetectable		 4r29D-5me4A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 ARG A 100
GLU A  82
TYR A 469
 None
 0.99A 4r29D-5mzsA:
undetectable		 4r29D-5mzsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nny WIPB

(Legionella
pneumophila) 		no annotation 3 ARG A 173
GLU A 154
TYR A 288
 None
 0.92A 4r29D-5nnyA:
undetectable		 4r29D-5nnyA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ov6 PORPHOBILINOGEN
DEAMINASE

(Bacillus
megaterium) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		3 ARG A 250
GLU A 187
TYR A 248
 None
 0.95A 4r29D-5ov6A:
undetectable		 4r29D-5ov6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tnu DNA-DEPENDENT ATPASE
XPBII

(Sulfurisphaera
tokodaii) 		no annotation 3 ARG A 205
GLU A 175
TYR A 213
 CL  A 511 ( 3.8A)
None
None
 0.94A 4r29D-5tnuA:
undetectable		 4r29D-5tnuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wan PYRIMIDINE
MONOOXYGENASE RUTA

(Escherichia
coli) 		PF00296
(Bac_luciferase) 		3 ARG A 141
GLU A 125
TYR A 137
 FMN  A 409 (-2.8A)
FMN  A 409 ( 4.8A)
None
 0.98A 4r29D-5wanA:
undetectable		 4r29D-5wanA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi UNCHARACTERIZED
PROTEIN
40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis;
Trichomonas
vaginalis) 		PF00333
(Ribosomal_S5)
PF03719
(Ribosomal_S5_C)
PF01249
(Ribosomal_S21e) 		3 ARG V  15
GLU C 252
TYR C  72
 None
 0.97A 4r29D-5xyiV:
undetectable		 4r29D-5xyiV:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az1 RIBOSOMAL PROTEIN
S8E
RIBOSOMAL PROTEIN
S17

(Leishmania
donovani;
Leishmania
donovani) 		no annotation
no annotation 		3 ARG K 187
GLU U  31
TYR K 211
 None
 0.95A 4r29D-6az1K:
undetectable		 4r29D-6az1K:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bba ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 ARG A 114
GLU A 152
TYR A 116
 None
 0.81A 4r29D-6bbaA:
undetectable		 4r29D-6bbaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli) 		no annotation 3 ARG A  41
GLU A 201
TYR A  43
 None
 0.96A 4r29D-6bogA:
undetectable		 4r29D-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c90 EXOSOME RNA HELICASE
MTR4,EXOSOME RNA
HELICASE MTR4
ZINC FINGER CCHC
DOMAIN-CONTAINING
PROTEIN 8

(Homo sapiens;
Homo sapiens) 		no annotation
no annotation 		3 ARG B 689
GLU A 201
TYR B 685
 None
 1.01A 4r29D-6c90B:
undetectable		 4r29D-6c90B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f34 AMINO ACID
TRANSPORTER

(Geobacillus
kaustophilus) 		no annotation 3 ARG A 327
GLU A 245
TYR A 323
 None
None
OLC  A 503 (-3.7A)
 0.94A 4r29D-6f34A:
0.9		 4r29D-6f34A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fd2 PUTATIVE APRAMYCIN
BIOSYNTHETIC
OXIDOREDUCTASE 4

(Streptoalloteichus
tenebrarius) 		no annotation 3 ARG B 319
GLU B 352
TYR B 213
 None
None
5AD  B 504 (-4.5A)
 0.73A 4r29D-6fd2B:
undetectable		 4r29D-6fd2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ffh METABOTROPIC
GLUTAMATE RECEPTOR
5,ENDOLYSIN

(Homo sapiens;
Escherichia
virus T4) 		no annotation 3 ARG A1148
GLU A1011
TYR A1161
 None
 0.90A 4r29D-6ffhA:
1.0		 4r29D-6ffhA:
undetectable