SIMILAR PATTERNS OF AMINO ACIDS FOR 4R1Z_A_AERA601
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ao0 | GLUTAMINEPHOSPHORIBOSYLPYROPHOSPHATEAMIDOTRANSFERASE (Bacillussubtilis) |
PF00156(Pribosyltran)PF13522(GATase_6) | 5 | ALA A 98ILE A 217GLY A 66ALA A 67THR A 16 | None | 0.94A | 4r1zA-1ao0A:undetectable | 4r1zA-1ao0A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bc5 | CHEMOTAXIS RECEPTORMETHYLTRANSFERASE (Salmonellaenterica) |
PF01739(CheR)PF03705(CheR_N) | 5 | SER A 132ILE A 133GLY A 127ALA A 163VAL A 206 | None | 1.08A | 4r1zA-1bc5A:undetectable | 4r1zA-1bc5A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d4e | FLAVOCYTOCHROME CFUMARATE REDUCTASE (Shewanellaoneidensis) |
PF00890(FAD_binding_2)PF14537(Cytochrom_c3_2) | 5 | ALA A 515ILE A 131GLY A 137ALA A 136VAL A 535 | NoneFAD A 600 ( 4.7A)NoneFAD A 600 (-3.3A)None | 1.19A | 4r1zA-1d4eA:undetectable | 4r1zA-1d4eA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dkg | MOLECULAR CHAPERONEDNAK (Escherichiacoli) |
PF00012(HSP70) | 5 | ASP D 8GLY D 374ALA D 174THR D 173VAL D 192 | None | 1.26A | 4r1zA-1dkgD:undetectable | 4r1zA-1dkgD:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f80 | HOLO-(ACYL CARRIERPROTEIN) SYNTHASE (Bacillussubtilis) |
PF01648(ACPS) | 5 | ALA A 59ILE A 15ASP A 8ALA A 111THR A 104 | NoneNoneNoneNone NA A1255 (-3.8A) | 1.27A | 4r1zA-1f80A:undetectable | 4r1zA-1f80A:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8f | BENZYL ALCOHOLDEHYDROGENASE (Acinetobactercalcoaceticus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 209TYR A 91GLY A 317ALA A 181VAL A 202 | NoneNoneNoneNoneNAD A 375 (-3.6A) | 1.15A | 4r1zA-1f8fA:undetectable | 4r1zA-1f8fA:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwi | CYTOCHROME P450154C1 (Streptomycescoelicolor) |
PF00067(p450) | 5 | SER A 347ASP A 324GLY A 322ALA A 320VAL A 316 | None | 1.07A | 4r1zA-1gwiA:29.9 | 4r1zA-1gwiA:26.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwi | CYTOCHROME P450154C1 (Streptomycescoelicolor) |
PF00067(p450) | 5 | SER A 347ILE A 346GLY A 322ALA A 320VAL A 316 | None | 1.07A | 4r1zA-1gwiA:29.9 | 4r1zA-1gwiA:26.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i2d | ATP SULFURYLASE (Penicilliumchrysogenum) |
PF01583(APS_kinase)PF01747(ATP-sulfurylase)PF14306(PUA_2) | 5 | ALA A 478ILE A 412ALA A 474THR A 398VAL A 500 | ADX A 575 (-4.5A)NoneNoneNoneNone | 1.18A | 4r1zA-1i2dA:0.2 | 4r1zA-1i2dA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl7 | MONOMER HEMOGLOBINCOMPONENT III (Glyceradibranchiata) |
PF00042(Globin) | 5 | ALA A 113SER A 138ILE A 137GLY A 107VAL A 62 | NoneNoneNoneNoneHEM A 148 ( 4.0A) | 1.12A | 4r1zA-1jl7A:1.4 | 4r1zA-1jl7A:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l1j | HEAT SHOCK PROTEASEHTRA (Thermotogamaritima) |
PF13365(Trypsin_2) | 5 | ALA A 159SER A 148GLY A 219ALA A 236VAL A 175 | None | 1.17A | 4r1zA-1l1jA:undetectable | 4r1zA-1l1jA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lzk | HEROIN ESTERASE (Rhodococcus sp.) |
PF07859(Abhydrolase_3) | 5 | ALA A 296SER A 255ILE A 188GLY A 304ALA A 305 | None | 1.15A | 4r1zA-1lzkA:undetectable | 4r1zA-1lzkA:21.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nr6 | CYTOCHROME P450 2C5 (Oryctolaguscuniculus) |
PF00067(p450) | 5 | ALA A 113ASP A 290GLY A 293ALA A 294THR A 298 | DIF A 501 (-3.6A)NoneDIF A 501 (-3.8A)DIF A 501 ( 3.3A)HEM A 500 ( 3.6A) | 0.95A | 4r1zA-1nr6A:44.1 | 4r1zA-1nr6A:32.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oa1 | HYDROXYLAMINEREDUCTASE (Desulfovibriovulgaris) |
PF03063(Prismane) | 5 | ALA A 404ILE A 372GLY A 457ALA A 456VAL A 453 | None | 1.26A | 4r1zA-1oa1A:1.2 | 4r1zA-1oa1A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pl8 | HUMAN SORBITOLDEHYDROGENASE (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 252ILE A 293GLY A 259ALA A 258VAL A 281 | NAD A 400 ( 3.8A)NoneNoneNoneNone | 1.00A | 4r1zA-1pl8A:undetectable | 4r1zA-1pl8A:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgr | PROTEIN (IMPORTINBETA SUBUNIT) (Homo sapiens) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | ILE A 393GLY A 349ALA A 348THR A 329VAL A 323 | None | 1.22A | 4r1zA-1qgrA:undetectable | 4r1zA-1qgrA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4d | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Pseudomonasdenitrificans(nomenrejiciendum)) |
PF00590(TP_methylase) | 5 | ALA A 241ILE A 141GLY A 135ALA A 131VAL A 181 | NoneNoneNoneSAH A1501 (-3.4A)None | 1.15A | 4r1zA-1s4dA:undetectable | 4r1zA-1s4dA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vi1 | FATTYACID/PHOSPHOLIPIDSYNTHESIS PROTEINPLSX (Bacillussubtilis) |
PF02504(FA_synthesis) | 5 | ALA A 16SER A 79GLY A 9ALA A 98VAL A 5 | None | 1.26A | 4r1zA-1vi1A:undetectable | 4r1zA-1vi1A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa4 | PCZA361.16 (Amycolatopsisorientalis) |
PF00908(dTDP_sugar_isom) | 5 | ALA A 153TYR A 64ILE A 89ASP A 151ALA A 177 | None | 1.24A | 4r1zA-1wa4A:undetectable | 4r1zA-1wa4A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdw | TRYPTOPHAN SYNTHASEBETA CHAIN 1 (Pyrococcusfuriosus) |
PF00291(PALP) | 5 | ALA B 296SER B 335GLY B 374ALA B 343VAL B 350 | NoneNoneNonePLP B 400 ( 3.8A)None | 1.19A | 4r1zA-1wdwB:undetectable | 4r1zA-1wdwB:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8t | HYPOTHETICAL PROTEINRV0983 (Mycobacteriumtuberculosis) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ALA A 119SER A 108GLY A 182ALA A 207VAL A 135 | None | 1.23A | 4r1zA-1y8tA:undetectable | 4r1zA-1y8tA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yzy | HYPOTHETICAL PROTEINHI1011 (Haemophilusinfluenzae) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | ALA A 307SER A 358ILE A 359GLY A 353ALA A 352 | None | 1.22A | 4r1zA-1yzyA:undetectable | 4r1zA-1yzyA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cwl | MANGANESE-FREEPSEUDOCATALASE (Thermusthermophilus) |
PF05067(Mn_catalase) | 5 | ALA A 121TYR A 291ASP A 277GLY A 275ALA A 274 | None | 1.17A | 4r1zA-2cwlA:undetectable | 4r1zA-2cwlA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g8y | MALATE/L-LACTATEDEHYDROGENASES (Escherichiacoli) |
PF02615(Ldh_2) | 5 | ALA A 182TYR A 56ILE A 268GLY A 122VAL A 144 | NAD A1001 (-3.2A)NoneEDO A1019 ( 4.7A)NAD A1001 (-3.9A)NAD A1001 (-4.4A) | 1.24A | 4r1zA-2g8yA:undetectable | 4r1zA-2g8yA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gko | SUBTILISINMICROBIAL SERINEPROTEINASES (Bacillussubtilis) |
PF00082(Peptidase_S8) | 5 | ALA A 79ILE A 262GLY A 25ALA A 96VAL A 134 | None | 1.17A | 4r1zA-2gkoA:undetectable | 4r1zA-2gkoA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gn1 | THREONINEDEHYDRATASECATABOLIC (Salmonellaenterica) |
PF00291(PALP) | 5 | ALA A 87ILE A 141GLY A 101ALA A 122VAL A 125 | None | 0.94A | 4r1zA-2gn1A:undetectable | 4r1zA-2gn1A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nq2 | HYPOTHETICAL ABCTRANSPORTER PERMEASEPROTEIN HI1471 (Haemophilusinfluenzae) |
PF01032(FecCD) | 5 | SER A 208GLY A 75ALA A 77THR A 286VAL A 82 | None | 1.26A | 4r1zA-2nq2A:undetectable | 4r1zA-2nq2A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o2q | FORMYLTETRAHYDROFOLATE DEHYDROGENASE (Rattusnorvegicus) |
PF00171(Aldedh) | 5 | TYR A 761SER A 805ILE A 809GLY A 711ALA A 710 | None | 1.20A | 4r1zA-2o2qA:undetectable | 4r1zA-2o2qA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o56 | PUTATIVE MANDELATERACEMASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 57SER A 328ILE A 327GLY A 43ALA A 95 | None | 0.97A | 4r1zA-2o56A:undetectable | 4r1zA-2o56A:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q7v | THIOREDOXINREDUCTASE (Deinococcusradiodurans) |
PF07992(Pyr_redox_2) | 5 | ALA A 303ILE A 14GLY A 20ALA A 19VAL A 285 | NoneNoneNoneFAD A 348 (-3.3A)None | 1.24A | 4r1zA-2q7vA:undetectable | 4r1zA-2q7vA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wua | ACETOACETYL COATHIOLASE (Helianthusannuus) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ALA A 55ILE A 98GLY A 162ALA A 398VAL A 146 | None | 1.22A | 4r1zA-2wuaA:undetectable | 4r1zA-2wuaA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ya1 | PUTATIVE ALKALINEAMYLOPULLULANASE (Streptococcuspneumoniae) |
PF00128(Alpha-amylase)PF02922(CBM_48)PF03714(PUD) | 5 | ALA A 453ILE A 513GLY A 518ALA A 562VAL A 478 | NoneSO4 A2152 (-4.4A)NoneNoneNone | 1.10A | 4r1zA-2ya1A:undetectable | 4r1zA-2ya1A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ya2 | PUTATIVE ALKALINEAMYLOPULLULANASE (Streptococcuspneumoniae) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 5 | ALA A -2ILE A 58GLY A 63ALA A 107VAL A 23 | None | 1.08A | 4r1zA-2ya2A:undetectable | 4r1zA-2ya2A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zle | PROTEASE DO (Escherichiacoli) |
PF00595(PDZ)PF13365(Trypsin_2) | 5 | ALA A 129SER A 118GLY A 178ALA A 196VAL A 145 | None | 1.25A | 4r1zA-2zleA:undetectable | 4r1zA-2zleA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejw | SMLSRB (Sinorhizobiummeliloti) |
PF13407(Peripla_BP_4) | 5 | SER A 250ILE A 63GLY A 19ALA A 21VAL A 34 | None | 1.23A | 4r1zA-3ejwA:undetectable | 4r1zA-3ejwA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3goc | ENDONUCLEASE V (Streptomycesavermitilis) |
PF04493(Endonuclease_5) | 5 | ALA A 90GLY A 117ALA A 127THR A 138VAL A 132 | None | 1.17A | 4r1zA-3gocA:undetectable | 4r1zA-3gocA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h4x | PHOSPHATIDYLINOSITOL-SPECIFICPHOSPHOLIPASE C1 (Streptomycesantibioticus) |
PF16670(PI-PLC-C1) | 5 | ALA A 263ILE A 194ASP A 262GLY A 237ALA A 238 | NoneNoneEOH A 348 ( 2.5A)NoneNone | 1.20A | 4r1zA-3h4xA:undetectable | 4r1zA-3h4xA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT ALPHACARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane)PF03598(CdhC) | 6 | ALA M 109SER A 618ILE A 623GLY M 28ALA M 29VAL A 228 | None | 1.20A | 4r1zA-3i04M:1.2 | 4r1zA-3i04M:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6d | PROTOPORPHYRINOGENOXIDASE (Bacillussubtilis) |
PF01593(Amino_oxidase) | 5 | SER A 374ILE A 375GLY A 371ALA A 370THR A 309 | None | 1.17A | 4r1zA-3i6dA:undetectable | 4r1zA-3i6dA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3io0 | ETUB PROTEIN (Clostridiumkluyveri) |
PF00936(BMC) | 5 | ALA A 284TYR A 249ILE A 265GLY A 231ALA A 225 | None | 1.21A | 4r1zA-3io0A:undetectable | 4r1zA-3io0A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipr | PTS SYSTEM, IIACOMPONENT (Enterococcusfaecalis) |
PF03610(EIIA-man) | 5 | ALA A 7ILE A 91ALA A 51THR A 50VAL A 79 | None | 1.26A | 4r1zA-3iprA:undetectable | 4r1zA-3iprA:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jv7 | ADH-A (Rhodococcusruber) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 193ILE A 315GLY A 311ALA A 310VAL A 304 | None | 1.27A | 4r1zA-3jv7A:undetectable | 4r1zA-3jv7A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k88 | CHLOROPHENOL-4-MONOOXYGENASE COMPONENT 1 (Burkholderiacepacia) |
PF01613(Flavin_Reduct) | 5 | ALA A1129GLY A1090ALA A1089THR A1173VAL A1033 | None | 1.15A | 4r1zA-3k88A:undetectable | 4r1zA-3k88A:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k9d | ALDEHYDEDEHYDROGENASE (Listeriamonocytogenes) |
PF00171(Aldedh) | 5 | ALA A 207SER A 132GLY A 114ALA A 113THR A 192 | None | 1.24A | 4r1zA-3k9dA:undetectable | 4r1zA-3k9dA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kl2 | PUTATIVEISOCHORISMATASE (Streptomycesavermitilis) |
PF00857(Isochorismatase) | 5 | ALA A 214TYR A 50ILE A 48ALA A 205THR A 206 | None | 1.23A | 4r1zA-3kl2A:undetectable | 4r1zA-3kl2A:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nwu | SERINE PROTEASEHTRA1 (Homo sapiens) |
PF13365(Trypsin_2) | 5 | ALA A 281SER A 270GLY A 341ALA A 354VAL A 297 | None | 1.21A | 4r1zA-3nwuA:undetectable | 4r1zA-3nwuA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8l | 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE (Oryctolaguscuniculus) |
PF00365(PFK) | 5 | ALA A 542ILE A 496ASP A 672GLY A 414ALA A 413 | None | 1.25A | 4r1zA-3o8lA:undetectable | 4r1zA-3o8lA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8l | 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE (Oryctolaguscuniculus) |
PF00365(PFK) | 5 | ALA A 542ILE A 525ASP A 672GLY A 414ALA A 413 | None | 1.22A | 4r1zA-3o8lA:undetectable | 4r1zA-3o8lA:21.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3pm0 | CYTOCHROME P450 1B1 (Homo sapiens) |
PF00067(p450) | 5 | ALA A 133ASP A 326GLY A 329ALA A 330THR A 334 | HEM A 900 (-3.3A)BHF A 800 (-3.4A)BHF A 800 ( 4.0A)HEM A 900 ( 3.4A)HEM A 900 ( 3.2A) | 0.40A | 4r1zA-3pm0A:41.5 | 4r1zA-3pm0A:31.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qe7 | URACIL PERMEASE (Escherichiacoli) |
PF00860(Xan_ur_permease) | 5 | ALA A 140ILE A 329GLY A 30ALA A 31VAL A 37 | NoneNoneNoneURA A 430 ( 3.8A)None | 1.04A | 4r1zA-3qe7A:undetectable | 4r1zA-3qe7A:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rpd | METHIONINE SYNTHASE(B12-INDEPENDENT) (Shewanella sp.W3-18-1) |
PF01717(Meth_synt_2) | 6 | ALA A 140TYR A 245ILE A 260ASP A 188ALA A 20THR A 320 | None | 1.44A | 4r1zA-3rpdA:undetectable | 4r1zA-3rpdA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3stj | PROTEASE DEGQ (Escherichiacoli) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ALA A 143SER A 132GLY A 200ALA A 218VAL A 159 | None | 1.20A | 4r1zA-3stjA:undetectable | 4r1zA-3stjA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3td9 | BRANCHED CHAIN AMINOACID ABCTRANSPORTER,PERIPLASMIC AMINOACID-BINDING PROTEIN (Thermotogamaritima) |
PF13458(Peripla_BP_6) | 5 | ALA A 292ASP A 244GLY A 242THR A 118VAL A 93 | EDO A 403 (-3.5A)EDO A 403 ( 2.8A)PHE A 400 ( 4.2A)PHE A 400 (-2.8A)PHE A 400 (-4.7A) | 1.12A | 4r1zA-3td9A:undetectable | 4r1zA-3td9A:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vab | DIAMINOPIMELATEDECARBOXYLASE 1 (Brucellamelitensis) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | ALA A 93ILE A 281GLY A 78ALA A 79THR A 81 | None | 1.02A | 4r1zA-3vabA:undetectable | 4r1zA-3vabA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbh | ALKALINE PHOSPHATASE (Halomonas sp.#593) |
PF00245(Alk_phosphatase) | 5 | TYR A 435ASP A 269GLY A 272ALA A 271THR A 279 | None ZN A 504 ( 2.1A)NoneNoneNone | 1.27A | 4r1zA-3wbhA:undetectable | 4r1zA-3wbhA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wfz | LACTO-N-BIOSEPHOSPHORYLASE (Bifidobacteriumlongum) |
PF09508(Lact_bio_phlase)PF17385(LBP_M)PF17386(LBP_C) | 5 | ALA A 347TYR A 471GLY A 340ALA A 388VAL A 484 | None | 1.22A | 4r1zA-3wfzA:undetectable | 4r1zA-3wfzA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ww3 | L-RIBOSE ISOMERASE (Cellulomonasparahominis) |
no annotation | 5 | ALA A 18TYR A 47ILE A 6GLY A 39ALA A 38 | None | 1.19A | 4r1zA-3ww3A:undetectable | 4r1zA-3ww3A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bb9 | GLUCOKINASEREGULATORY PROTEIN (Homo sapiens) |
no annotation | 5 | ALA A 230SER A 110ILE A 178GLY A 181VAL A 187 | NoneF1P A 702 (-2.6A)NoneF1P A 702 (-3.6A)None | 1.06A | 4r1zA-4bb9A:undetectable | 4r1zA-4bb9A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4biz | SENSOR PROTEIN CPXA (Escherichiacoli) |
PF00512(HisKA)PF00672(HAMP)PF02518(HATPase_c) | 5 | ILE A 357GLY A 420ALA A 422THR A 426VAL A 435 | NoneADP A 501 (-3.6A)NoneNoneNone | 1.18A | 4r1zA-4bizA:undetectable | 4r1zA-4bizA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dn7 | ABC TRANSPORTER,ATP-BINDING PROTEIN (Methanosarcinamazei) |
PF01458(UPF0051) | 5 | SER A 107ILE A 162ASP A 128ALA A 127THR A 122 | None | 1.26A | 4r1zA-4dn7A:undetectable | 4r1zA-4dn7A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvy | CYTOTOXICITY-ASSOCIATED IMMUNODOMINANTANTIGEN (Helicobacterpylori) |
no annotation | 5 | ALA P 62ILE P 215GLY P 174ALA P 173VAL P 107 | None | 1.17A | 4r1zA-4dvyP:undetectable | 4r1zA-4dvyP:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irv | CYTOTOXICITY-ASSOCIATED IMMUNODOMINANTANTIGEN (Helicobacterpylori) |
no annotation | 5 | ALA A 62ILE A 215GLY A 174ALA A 173VAL A 107 | None | 1.27A | 4r1zA-4irvA:undetectable | 4r1zA-4irvA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jmd | PUTATIVEUNCHARACTERIZEDPROTEIN MPPR (Streptomyceshygroscopicus) |
PF06314(ADC) | 5 | ALA A 92ILE A 248ASP A 66GLY A 276VAL A 62 | None | 1.14A | 4r1zA-4jmdA:undetectable | 4r1zA-4jmdA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n4r | LPS-ASSEMBLYLIPOPROTEIN LPTE (Salmonellaenterica) |
PF04390(LptE) | 5 | ALA B 50ASP B 149ALA B 151THR B 120VAL B 80 | None | 0.94A | 4r1zA-4n4rB:undetectable | 4r1zA-4n4rB:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4na3 | POLYKETIDE SYNTHASEPKSJ (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A 182SER A 160GLY A 120ALA A 198VAL A 100 | None | 1.17A | 4r1zA-4na3A:undetectable | 4r1zA-4na3A:21.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 5 | ALA A 113ASP A 298GLY A 301ALA A 302VAL A 483 | HEM A 600 ( 2.9A)3QZ A 601 (-3.5A)3QZ A 601 ( 3.0A)3QZ A 601 (-2.9A)3QZ A 601 (-4.1A) | 0.96A | 4r1zA-4nkyA:51.1 | 4r1zA-4nkyA:46.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 8 | ALA A 113TYR A 201ILE A 205ASP A 298GLY A 301ALA A 302THR A 306VAL A 482 | HEM A 600 ( 2.9A)None3QZ A 601 ( 3.4A)3QZ A 601 (-3.5A)3QZ A 601 ( 3.0A)3QZ A 601 (-2.9A)HEM A 600 ( 3.2A)3QZ A 601 (-4.1A) | 0.68A | 4r1zA-4nkyA:51.1 | 4r1zA-4nkyA:46.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oec | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Thermococcuskodakarensis) |
PF03009(GDPD) | 5 | ALA A 101ILE A 231GLY A 14ALA A 30VAL A 9 | None | 1.28A | 4r1zA-4oecA:undetectable | 4r1zA-4oecA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oy8 | PUTATIVE SECRETEDCELLULOSE-BINDINGPROTEIN (Streptomycescoelicolor) |
PF03067(LPMO_10) | 5 | ALA A 104ILE A 209ASP A 101GLY A 100ALA A 99 | None | 1.24A | 4r1zA-4oy8A:undetectable | 4r1zA-4oy8A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pel | PENICILLIN G ACYLASESUBUNIT BETA (Kluyveracryocrescens) |
PF01804(Penicil_amidase) | 5 | ALA B 430GLY B 343ALA B 345THR B 447VAL B 442 | None | 1.23A | 4r1zA-4pelB:undetectable | 4r1zA-4pelB:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxl | CYTOSOLIC ALDEHYDEDEHYDROGENASE RF2C (Zea mays) |
PF00171(Aldedh) | 5 | ALA A 93GLY A 125ALA A 126THR A 173VAL A 100 | None | 1.22A | 4r1zA-4pxlA:undetectable | 4r1zA-4pxlA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q0s | L-RIBOSE ISOMERASE (Acinetobactersp. DL-28) |
no annotation | 5 | ALA A 18TYR A 47ILE A 6GLY A 39ALA A 38 | None | 1.21A | 4r1zA-4q0sA:undetectable | 4r1zA-4q0sA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qyr | AT-LESS POLYKETIDESYNTHASE (Streptomycesplatensis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 5 | ALA A2717SER A2695GLY A2656ALA A2733VAL A2637 | None | 1.24A | 4r1zA-4qyrA:undetectable | 4r1zA-4qyrA:21.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r20 | CYTOCHROME P450FAMILY 17POLYPEPTIDE 2 (Danio rerio) |
PF00067(p450) | 7 | ALA A 120TYR A 208ILE A 212GLY A 301ALA A 302THR A 306VAL A 480 | AER A 602 (-3.7A)NoneAER A 602 (-3.2A)AER A 602 ( 3.8A)HEM A 601 (-3.4A)HEM A 601 ( 3.3A)AER A 602 ( 4.9A) | 0.74A | 4r1zA-4r20A:24.7 | 4r1zA-4r20A:46.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rgb | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | SER A 260ILE A 263GLY A 33ALA A 28VAL A 23 | None | 0.94A | 4r1zA-4rgbA:undetectable | 4r1zA-4rgbA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywo | MERCURIC REDUCTASE (Metallosphaerasedula) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 310ILE A 7GLY A 13ALA A 12VAL A 293 | NoneFAD A 501 ( 4.9A)NoneFAD A 501 (-3.8A)None | 1.17A | 4r1zA-4ywoA:undetectable | 4r1zA-4ywoA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z38 | MLNA (Bacillusvelezensis) |
no annotation | 5 | ALA A 565SER A 577ILE A 578GLY A 554ALA A 553 | NoneFMN A 900 (-2.6A)NoneFMN A 900 (-3.2A)FMN A 900 ( 4.3A) | 1.26A | 4r1zA-4z38A:undetectable | 4r1zA-4z38A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg8 | ENDOGLUCANASE (Perinereisbrevicirris) |
PF00759(Glyco_hydro_9) | 5 | ALA A 87TYR A 23SER A 19ILE A 20GLY A 425 | None | 1.17A | 4r1zA-4zg8A:undetectable | 4r1zA-4zg8A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zg8 | ENDOGLUCANASE (Perinereisbrevicirris) |
PF00759(Glyco_hydro_9) | 5 | TYR A 23SER A 19ILE A 20GLY A 425ALA A 428 | None | 1.24A | 4r1zA-4zg8A:undetectable | 4r1zA-4zg8A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a35 | GLYCINE CLEAVAGESYSTEM H PROTEIN (Streptococcuspyogenes) |
PF01597(GCV_H) | 5 | SER A 63ILE A 49ASP A 41ALA A 68THR A 97 | None | 1.09A | 4r1zA-5a35A:undetectable | 4r1zA-5a35A:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8r | METHYL-COENZYME MREDUCTASE II,SUBUNIT BETA (Methanothermobactermarburgensis) |
PF02240(MCR_gamma) | 5 | ALA C 99ILE C 88ASP C 92GLY C 152VAL C 141 | None | 1.17A | 4r1zA-5a8rC:undetectable | 4r1zA-5a8rC:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bk6 | PUTATIVE AMIDASE (Rhizobiumleguminosarum) |
no annotation | 5 | ALA A 208ILE A 35GLY A 198ALA A 199THR A 200 | None | 1.18A | 4r1zA-5bk6A:undetectable | 4r1zA-5bk6A:10.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw5 | T-COMPLEX PROTEIN 1SUBUNIT BETA (Saccharomycescerevisiae) |
PF00118(Cpn60_TCP1) | 5 | SER b 462ILE b 463ASP b 481ALA b 480THR b 478 | None | 1.17A | 4r1zA-5gw5b:undetectable | 4r1zA-5gw5b:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izd | D-GLYCERALDEHYDEDEHYDROGENASE(NADP(+)) (Thermoplasmaacidophilum) |
PF00171(Aldedh) | 5 | ILE A 201ASP A 47ALA A 49THR A 168VAL A 143 | None | 1.00A | 4r1zA-5izdA:undetectable | 4r1zA-5izdA:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mg5 | HYDROXYMETHYLGLUTARYL-COA SYNTHASE (Pseudomonasprotegens) |
no annotation | 5 | ALA A 278TYR A 322SER A 10GLY A 12ALA A 62 | None | 1.22A | 4r1zA-5mg5A:undetectable | 4r1zA-5mg5A:12.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3w | ARYLDIALKYLPHOSPHATASE (Sulfolobussolfataricus) |
no annotation | 5 | TYR A 208ILE A 212ASP A 222GLY A 201THR A 239 | None | 1.27A | 4r1zA-5w3wA:undetectable | 4r1zA-5w3wA:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7a | ACYLOXYACYLHYDROLASE LARGESUBUNIT (Oryctolaguscuniculus) |
no annotation | 5 | ALA B 341ILE B 366ASP B 261GLY B 264ALA B 265 | None | 1.09A | 4r1zA-5w7aB:undetectable | 4r1zA-5w7aB:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x3x | UNCHARACTERIZEDPROTEIN CBIQ (Rhodobactercapsulatus) |
PF02361(CbiQ) | 5 | ALA Q 112ILE Q 237GLY Q 29ALA Q 32VAL Q 37 | None | 1.14A | 4r1zA-5x3xQ:undetectable | 4r1zA-5x3xQ:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xcb | PROBABLE SURFACEPROTEIN (Clostridiumperfringens) |
no annotation | 5 | ALA A 292TYR A 255ILE A 271GLY A 239VAL A 259 | None | 1.24A | 4r1zA-5xcbA:undetectable | 4r1zA-5xcbA:10.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xcc | PROBABLE SURFACEPROTEIN (Clostridiumperfringens) |
no annotation | 5 | ALA A 292TYR A 255ILE A 271GLY A 239VAL A 259 | None | 1.24A | 4r1zA-5xccA:undetectable | 4r1zA-5xccA:10.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xum | HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (Thermotogamaritima) |
no annotation | 5 | ALA A 55TYR A 162ILE A 165GLY A 86VAL A 68 | None | 1.14A | 4r1zA-5xumA:undetectable | 4r1zA-5xumA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b82 | CYTOCHROME P450,FAMILY 17, SUBFAMILYA, POLYPEPTIDE 1 (Danio rerio) |
no annotation | 7 | ALA A 126TYR A 214ILE A 218GLY A 312ALA A 313THR A 317VAL A 493 | HEM A 601 (-3.8A)NoneAER A 602 (-3.9A)AER A 602 ( 3.7A)HEM A 601 (-3.6A)HEM A 601 ( 3.7A)AER A 602 ( 4.7A) | 0.68A | 4r1zA-6b82A:52.7 | 4r1zA-6b82A:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b82 | CYTOCHROME P450,FAMILY 17, SUBFAMILYA, POLYPEPTIDE 1 (Danio rerio) |
no annotation | 6 | ALA A 126TYR A 214SER A 215GLY A 312ALA A 313VAL A 494 | HEM A 601 (-3.8A)NoneAER A 602 (-3.4A)AER A 602 ( 3.7A)HEM A 601 (-3.6A)None | 0.99A | 4r1zA-6b82A:52.7 | 4r1zA-6b82A:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b82 | CYTOCHROME P450,FAMILY 17, SUBFAMILYA, POLYPEPTIDE 1 (Danio rerio) |
no annotation | 7 | ALA A 126TYR A 214SER A 215ILE A 218GLY A 312ALA A 313THR A 317 | HEM A 601 (-3.8A)NoneAER A 602 (-3.4A)AER A 602 (-3.9A)AER A 602 ( 3.7A)HEM A 601 (-3.6A)HEM A 601 ( 3.7A) | 0.44A | 4r1zA-6b82A:52.7 | 4r1zA-6b82A:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6co7 | PREDICTED PROTEIN (Nematostellavectensis) |
no annotation | 5 | ALA A 190TYR A 395ILE A 324GLY A 162VAL A 142 | None | 1.11A | 4r1zA-6co7A:undetectable | 4r1zA-6co7A:11.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fah | CAFFEYL-COAREDUCTASE-ETFCOMPLEX SUBUNIT CARE (Acetobacteriumwoodii) |
no annotation | 5 | ALA A 344SER A 354GLY A 350ALA A 349VAL A 371 | FAD A 401 (-3.5A)NoneNoneNoneNone | 1.20A | 4r1zA-6fahA:undetectable | 4r1zA-6fahA:10.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fah | CAFFEYL-COAREDUCTASE-ETFCOMPLEX SUBUNIT CARE (Acetobacteriumwoodii) |
no annotation | 5 | ALA A 344SER A 354ILE A 357GLY A 350ALA A 349 | FAD A 401 (-3.5A)NoneNoneNoneNone | 1.17A | 4r1zA-6fahA:undetectable | 4r1zA-6fahA:10.88 |