SIMILAR PATTERNS OF AMINO ACIDS FOR 4QYN_A_RTLA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1atj PEROXIDASE C1A

(Armoracia
rusticana) 		PF00141
(peroxidase) 		5 ILE A  53
ALA A  74
THR A  21
VAL A  18
LEU A 101
 None
 1.21A 4qynA-1atjA:
0.0		 4qynA-1atjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1atj PEROXIDASE C1A

(Armoracia
rusticana) 		PF00141
(peroxidase) 		5 PHE A  77
ILE A  53
ALA A  74
THR A  21
LEU A 101
 None
 1.32A 4qynA-1atjA:
0.0		 4qynA-1atjA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fot CAMP-DEPENDENT
PROTEIN KINASE TYPE
1

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		5 ILE A 167
TYR A 190
VAL A 186
LEU A 218
LEU A 349
 None
 1.31A 4qynA-1fotA:
undetectable		 4qynA-1fotA:
17.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ggl PROTEIN (CELLULAR
RETINOL-BINDING
PROTEIN III)

(Homo sapiens) 		PF00061
(Lipocalin) 		8 ILE A  25
ALA A  33
LYS A  40
THR A  53
TYR A  60
VAL A  62
TRP A 106
LEU A 117
 None
 0.62A 4qynA-1gglA:
23.9		 4qynA-1gglA:
50.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae) 		PF01569
(PAP2) 		5 ILE A  87
ALA A  78
VAL A 205
LEU A  99
LEU A 173
 None
 1.28A 4qynA-1iw8A:
undetectable		 4qynA-1iw8A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ixp PYRIDOXINE
5'-PHOSPHATE
SYNTHASE

(Escherichia
coli) 		PF03740
(PdxJ) 		5 ALA A 178
THR A 156
TYR A 159
LEU A 172
LEU A 212
 None
 1.29A 4qynA-1ixpA:
undetectable		 4qynA-1ixpA:
20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kqx CELLULAR
RETINOL-BINDING
PROTEIN

(Danio rerio) 		PF00061
(Lipocalin) 		9 ILE A  25
ALA A  33
LYS A  40
THR A  51
THR A  53
VAL A  62
LEU A  77
TRP A 106
LEU A 117
 None
 1.14A 4qynA-1kqxA:
25.1		 4qynA-1kqxA:
75.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kqx CELLULAR
RETINOL-BINDING
PROTEIN

(Danio rerio) 		PF00061
(Lipocalin) 		6 MET A  20
ILE A  25
THR A  51
TYR A  60
VAL A  62
TRP A 106
 None
 1.46A 4qynA-1kqxA:
25.1		 4qynA-1kqxA:
75.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1kqx CELLULAR
RETINOL-BINDING
PROTEIN

(Danio rerio) 		PF00061
(Lipocalin) 		10 PHE A  16
MET A  20
ILE A  25
ALA A  33
LYS A  40
THR A  51
THR A  53
VAL A  62
TRP A 106
LEU A 117
 None
 0.65A 4qynA-1kqxA:
25.1		 4qynA-1kqxA:
75.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lpj RETINOL-BINDING
PROTEIN IV, CELLULAR

(Homo sapiens) 		PF00061
(Lipocalin) 		10 PHE A  16
MET A  20
ILE A  25
ALA A  33
LYS A  40
THR A  53
VAL A  62
LEU A  77
TRP A 106
LEU A 117
 None
 0.74A 4qynA-1lpjA:
25.4		 4qynA-1lpjA:
58.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE

(Enterobacter
cloacae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 PHE A 401
ILE A 373
ALA A 390
THR A 242
LEU A 221
 None
 1.33A 4qynA-1ovmA:
0.0		 4qynA-1ovmA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qo4 PEROXIDASE

(Arabidopsis
thaliana) 		PF00141
(peroxidase) 		5 ILE A  53
ALA A  74
THR A  21
VAL A  18
LEU A 101
 None
 1.21A 4qynA-1qo4A:
0.0		 4qynA-1qo4A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sgo PROTEIN C14ORF129

(Homo sapiens) 		PF05303
(DUF727) 		5 ALA A  91
THR A  81
TYR A  65
VAL A  63
LEU A  57
 None
 1.37A 4qynA-1sgoA:
undetectable		 4qynA-1sgoA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vim HYPOTHETICAL PROTEIN
AF1796

(Archaeoglobus
fulgidus) 		PF01380
(SIS) 		5 PHE A 149
ILE A  48
THR A  23
VAL A  24
LEU A 157
 None
 1.16A 4qynA-1vimA:
undetectable		 4qynA-1vimA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vmd METHYLGLYOXAL
SYNTHASE

(Thermotoga
maritima) 		PF02142
(MGS) 		5 ILE A 112
ALA A  80
THR A  52
THR A  49
LEU A 109
 None
None
SO4  A 167 (-4.1A)
SO4  A 167 (-3.4A)
None
 1.35A 4qynA-1vmdA:
undetectable		 4qynA-1vmdA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1s RAS-RELATED PROTEIN
M-RAS

(Mus musculus) 		PF00071
(Ras) 		5 ILE A 150
TYR A  92
VAL A  94
LEU A 123
LEU A  29
 None
 0.91A 4qynA-1x1sA:
undetectable		 4qynA-1x1sA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x44 MYOSIN-BINDING
PROTEIN C, SLOW-TYPE

(Homo sapiens) 		PF07679
(I-set) 		5 ILE A  68
ALA A  77
THR A  83
VAL A  38
LEU A  66
 None
 1.31A 4qynA-1x44A:
undetectable		 4qynA-1x44A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xf1 C5A PEPTIDASE

(Streptococcus
pyogenes) 		PF00082
(Peptidase_S8)
PF02225
(PA)
PF06280
(fn3_5)
PF13585
(CHU_C) 		5 THR A1020
THR A1022
TYR A1010
VAL A1012
LEU A 949
 None
 0.98A 4qynA-1xf1A:
undetectable		 4qynA-1xf1A:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybm UNKNOWN PROTEIN
AT5G02240

(Arabidopsis
thaliana) 		PF13460
(NAD_binding_10) 		5 PHE A 246
ILE A 172
ALA A 215
THR A 239
LEU A 228
 None
 1.33A 4qynA-1ybmA:
undetectable		 4qynA-1ybmA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bkw ALANINE-GLYOXYLATE
AMINOTRANSFERASE 1

(Saccharomyces
cerevisiae) 		PF00266
(Aminotran_5) 		5 ILE A 344
THR A 142
THR A 144
VAL A  91
LEU A 196
 GLV  A1384 ( 4.3A)
None
PLP  A1201 (-4.3A)
None
None
 1.25A 4qynA-2bkwA:
undetectable		 4qynA-2bkwA:
15.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2cbr PROTEIN (CRABP-I)

(Bos taurus) 		PF00061
(Lipocalin) 		5 PHE A  15
ALA A  32
THR A  54
TRP A 109
LEU A 120
 None
A80  A 201 ( 4.1A)
A80  A 201 (-3.5A)
None
None
 0.75A 4qynA-2cbrA:
20.1		 4qynA-2cbrA:
35.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d42 NON-TOXIC CRYSTAL
PROTEIN

(Bacillus
thuringiensis) 		PF03318
(ETX_MTX2) 		5 ILE A 200
ALA A 221
THR A  90
LEU A   6
LEU A  41
 None
 1.06A 4qynA-2d42A:
undetectable		 4qynA-2d42A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iii S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROENZYME

(Aquifex
aeolicus) 		PF02675
(AdoMet_dc) 		5 MET A  94
ILE A  98
ALA A  11
THR A  70
LEU A 101
 None
 1.09A 4qynA-2iiiA:
undetectable		 4qynA-2iiiA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lsj DNA REPAIR PROTEIN
REV1

(Mus musculus) 		PF16727
(REV1_C) 		5 MET A  85
ILE A  44
ALA A  96
LEU A  40
LEU A 116
 None
 0.97A 4qynA-2lsjA:
undetectable		 4qynA-2lsjA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohh TYPE A FLAVOPROTEIN
FPRA

(Methanothermobacter
thermautotrophicus) 		PF00258
(Flavodoxin_1)
PF00753
(Lactamase_B) 		5 PHE A 167
ALA A 230
THR A  15
TYR A  13
LEU A  48
 None
 1.36A 4qynA-2ohhA:
undetectable		 4qynA-2ohhA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ory LIPASE

(Photobacterium
sp. M37) 		PF01764
(Lipase_3) 		5 PHE A 216
ALA A 217
VAL A 170
LEU A 224
LEU A 133
 None
 1.21A 4qynA-2oryA:
undetectable		 4qynA-2oryA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pft EXOCYTOSIS PROTEIN

(Mus musculus) 		PF03081
(Exo70) 		5 ALA A 440
TYR A 466
VAL A 470
LEU A 394
LEU A 432
 None
 1.31A 4qynA-2pftA:
undetectable		 4qynA-2pftA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr7 RIBOSOMAL PROTEIN S6
KINASE ALPHA-3

(Mus musculus) 		PF00069
(Pkinase) 		5 PHE A 562
ALA A 565
THR A 522
THR A 526
LEU A 540
 None
 1.28A 4qynA-2qr7A:
undetectable		 4qynA-2qr7A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rad SUCCINOGLYCAN
BIOSYNTHESIS PROTEIN

(Bacillus cereus) 		PF05139
(Erythro_esteras) 		5 PHE A 107
ALA A  75
THR A 341
VAL A 431
LEU A  68
 None
 1.29A 4qynA-2radA:
undetectable		 4qynA-2radA:
14.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2rcq RETINOL-BINDING
PROTEIN II, CELLULAR

(Homo sapiens) 		PF00061
(Lipocalin) 		11 PHE A  16
MET A  20
ILE A  25
ALA A  33
LYS A  40
THR A  51
THR A  53
VAL A  62
LEU A  77
TRP A 106
LEU A 117
 None
 0.58A 4qynA-2rcqA:
26.3		 4qynA-2rcqA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rk5 PUTATIVE HEMOLYSIN

(Streptococcus
mutans) 		PF03471
(CorC_HlyC) 		5 ILE A  13
THR A  49
TYR A  43
VAL A  47
LEU A  83
 None
 1.36A 4qynA-2rk5A:
undetectable		 4qynA-2rk5A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnt RIBOSOMAL PROTEIN S6
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		5 PHE A 558
ALA A 561
THR A 518
THR A 522
LEU A 536
 None
 1.26A 4qynA-2wntA:
undetectable		 4qynA-2wntA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xtl CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		5 MET A 249
ALA A 311
THR A 232
VAL A 197
LEU A 284
 None
 1.28A 4qynA-2xtlA:
undetectable		 4qynA-2xtlA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yhg CELLULOSE-BINDING
PROTEIN

(Saccharophagus
degradans) 		PF07632
(DUF1593) 		5 PHE A 596
ALA A 593
TYR A 553
VAL A 527
LEU A 602
 None
 1.30A 4qynA-2yhgA:
undetectable		 4qynA-2yhgA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuc DNA REPAIR AND
RECOMBINATION
PROTEIN RADA

(Sulfolobus
solfataricus) 		PF08423
(Rad51)
PF14520
(HHH_5) 		5 ILE A 319
THR A 108
THR A 110
LEU A 127
LEU A 305
 None
 1.12A 4qynA-2zucA:
undetectable		 4qynA-2zucA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5v ALPHA-GALACTOSIDASE

(Umbelopsis
vinacea) 		PF16499
(Melibiase_2) 		5 PHE A 194
MET A 218
ILE A 221
ALA A 330
VAL A 290
 None
 1.33A 4qynA-3a5vA:
undetectable		 4qynA-3a5vA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9y AMMONIUM TRANSPORTER
FAMILY RH-LIKE
PROTEIN

(Nitrosomonas
europaea) 		PF00909
(Ammonium_transp) 		5 ILE A 222
ALA A 164
THR A 114
VAL A 139
LEU A  51
 UNL  A 420 (-4.1A)
UNL  A 420 (-3.6A)
None
None
None
 1.25A 4qynA-3b9yA:
undetectable		 4qynA-3b9yA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		5 ILE A 380
ALA A 432
VAL A 400
LEU A 391
LEU A 352
 None
 1.11A 4qynA-3bc8A:
undetectable		 4qynA-3bc8A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cph RAS-RELATED PROTEIN
SEC4

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		5 ILE A 156
TYR A 100
VAL A 102
LEU A 130
LEU A  36
 None
 0.90A 4qynA-3cphA:
undetectable		 4qynA-3cphA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpr DIHYDRODIPICOLINATE
SYNTHETASE

(Corynebacterium
glutamicum) 		PF00701
(DHDPS) 		5 MET A  24
ALA A  43
VAL A 303
LEU A 269
LEU A 227
 None
 1.27A 4qynA-3cprA:
undetectable		 4qynA-3cprA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eaf ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN

(Aeropyrum
pernix) 		PF13458
(Peripla_BP_6) 		5 ILE A 122
ALA A  72
THR A  83
VAL A 348
LEU A 341
 None
 1.29A 4qynA-3eafA:
0.7		 4qynA-3eafA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3faw RETICULOCYTE BINDING
PROTEIN

(Streptococcus
agalactiae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		5 ILE A 427
THR A 401
TYR A 456
VAL A 383
LEU A 415
 None
 1.32A 4qynA-3fawA:
undetectable		 4qynA-3fawA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgw PUTATIVE
PHOSPHOLIPASE B-LIKE
2

(Mus musculus) 		PF04916
(Phospholip_B) 		5 ALA A 357
THR A 419
THR A 404
VAL A 402
LEU A 324
 None
 1.35A 4qynA-3fgwA:
undetectable		 4qynA-3fgwA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gt5 N-ACETYLGLUCOSAMINE
2-EPIMERASE

(Xylella
fastidiosa) 		PF07221
(GlcNAc_2-epim) 		5 PHE A 155
ALA A 167
THR A  62
TYR A 103
VAL A  91
 None
 1.29A 4qynA-3gt5A:
undetectable		 4qynA-3gt5A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hra ANKYRIN REPEAT
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF12796
(Ank_2)
PF13857
(Ank_5) 		5 MET A  91
ILE A  65
ALA A  79
THR A  18
VAL A  21
 None
 1.32A 4qynA-3hraA:
undetectable		 4qynA-3hraA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jy6 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Lactobacillus
brevis) 		PF13407
(Peripla_BP_4) 		6 ILE A 282
ALA A 277
THR A 243
VAL A 271
LEU A 289
LEU A 232
 None
 1.34A 4qynA-3jy6A:
undetectable		 4qynA-3jy6A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ktd PREPHENATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF02153
(PDH) 		5 MET A  77
ILE A  80
ALA A 105
THR A 149
VAL A 170
 None
 1.31A 4qynA-3ktdA:
undetectable		 4qynA-3ktdA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lkw FUSION PROTEIN OF
NONSTRUCTURAL
PROTEIN 2B AND
NONSTRUCTURAL
PROTEIN 3

(Dengue virus) 		PF00949
(Peptidase_S7)
PF01002
(Flavi_NS2B) 		5 ILE A 196
THR A 103
VAL A 102
LEU A 199
LEU A   9
 None
 1.27A 4qynA-3lkwA:
undetectable		 4qynA-3lkwA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ngo CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		5 ILE A 385
ALA A 357
THR A 496
LEU A 386
LEU A 538
 None
 1.28A 4qynA-3ngoA:
undetectable		 4qynA-3ngoA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pft FLAVIN REDUCTASE

(Mycolicibacterium
goodii) 		PF01613
(Flavin_Reduct) 		5 PHE A  53
ILE A  73
ALA A  38
LEU A  71
LEU A 124
 None
None
FMN  A 401 (-3.5A)
None
None
 1.06A 4qynA-3pftA:
undetectable		 4qynA-3pftA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdl OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE

(Helicobacter
pylori) 		PF00881
(Nitroreductase) 		5 PHE A  54
MET A  84
ILE A 186
ALA A  40
TYR A 141
 None
 1.22A 4qynA-3qdlA:
undetectable		 4qynA-3qdlA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3slu M23 PEPTIDASE DOMAIN
PROTEIN

(Neisseria
meningitidis) 		PF01551
(Peptidase_M23) 		5 PHE A 190
ILE A 224
ALA A 238
LEU A 207
LEU A 199
 None
 1.33A 4qynA-3sluA:
undetectable		 4qynA-3sluA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5t PUTATIVE
GLYCOSYLTRANSFERASE

(Streptomyces
hygroscopicus) 		PF00982
(Glyco_transf_20) 		5 ILE A 403
ALA A 436
THR A 354
THR A 316
VAL A 355
 None
 1.19A 4qynA-3t5tA:
undetectable		 4qynA-3t5tA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw8 RAS-RELATED PROTEIN
RAB-35

(Homo sapiens) 		PF00071
(Ras) 		5 ILE B 144
TYR B  88
VAL B  90
LEU B 117
LEU B  24
 None
 0.93A 4qynA-3tw8B:
undetectable		 4qynA-3tw8B:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uve CARVEOL
DEHYDROGENASE
((+)-TRANS-CARVEOL
DEHYDROGENASE)

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		5 ILE A  34
ALA A  15
THR A 139
VAL A 144
LEU A 158
 None
 1.23A 4qynA-3uveA:
undetectable		 4qynA-3uveA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vcy UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Aliivibrio
fischeri) 		PF00275
(EPSP_synthase) 		5 ILE A   6
ALA A 380
THR A 238
LEU A 407
LEU A 371
 None
 1.01A 4qynA-3vcyA:
undetectable		 4qynA-3vcyA:
14.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wbg FATTY ACID-BINDING
PROTEIN, HEART

(Homo sapiens) 		PF00061
(Lipocalin) 		5 PHE A  16
MET A  20
ALA A  33
THR A  53
LEU A 115
 2AN  A 201 ( 4.9A)
2AN  A 201 ( 3.9A)
2AN  A 201 (-3.8A)
2AN  A 201 ( 4.0A)
None
 0.80A 4qynA-3wbgA:
20.6		 4qynA-3wbgA:
37.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE

(Vibrio
parahaemolyticus) 		PF01522
(Polysacc_deac_1) 		5 ILE A  30
ALA A 318
VAL A  45
LEU A  32
LEU A 243
 None
 1.25A 4qynA-3wx7A:
undetectable		 4qynA-3wx7A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zuq BOTULINUM NEUROTOXIN
TYPE B

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07952
(Toxin_trans) 		5 PHE A 608
ILE A 799
ALA A 640
LEU A 795
LEU A 590
 None
 1.35A 4qynA-3zuqA:
undetectable		 4qynA-3zuqA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bom ENVELOPE
GLYCOPROTEIN B

(Human
alphaherpesvirus
1) 		PF00606
(Glycoprotein_B)
PF17416
(Glycoprot_B_PH1)
PF17417
(Glycoprot_B_PH2) 		5 PHE A 395
ILE A 391
ALA A 504
THR A 497
LEU A 443
 None
 1.35A 4qynA-4bomA:
undetectable		 4qynA-4bomA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci8 ECHINODERM
MICROTUBULE-ASSOCIAT
ED PROTEIN-LIKE 1

(Homo sapiens) 		PF00400
(WD40)
PF03451
(HELP) 		5 ILE A 551
ALA A 572
VAL A 787
LEU A 549
LEU A 221
 None
 1.33A 4qynA-4ci8A:
2.7		 4qynA-4ci8A:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dup QUINONE
OXIDOREDUCTASE

(Rhizobium etli) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 PHE A 138
ILE A 216
THR A 161
LEU A 218
LEU A 285
 None
 1.34A 4qynA-4dupA:
undetectable		 4qynA-4dupA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dws CHI2

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		5 ILE A 475
ALA A 460
THR A 439
VAL A 564
LEU A 477
 None
None
None
MLY  A 565 ( 3.2A)
None
 1.28A 4qynA-4dwsA:
undetectable		 4qynA-4dwsA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4g METHYLMALONATE-SEMIA
LDEHYDE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		5 MET A 252
ILE A 282
ALA A 266
VAL A 346
LEU A 387
 None
 1.19A 4qynA-4e4gA:
undetectable		 4qynA-4e4gA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eys MCCC FAMILY PROTEIN

(Streptococcus
pneumoniae) 		PF02016
(Peptidase_S66) 		5 MET A  73
ILE A   5
THR A  83
THR A 111
LEU A 118
 None
 1.18A 4qynA-4eysA:
undetectable		 4qynA-4eysA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f9d POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Escherichia
coli) 		PF01522
(Polysacc_deac_1)
PF14883
(GHL13) 		5 ILE A 462
ALA A 454
VAL A 442
LEU A 521
LEU A 375
 None
 0.98A 4qynA-4f9dA:
undetectable		 4qynA-4f9dA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2p CHAPERONE SURA

(Salmonella
enterica) 		PF13616
(Rotamase_3) 		5 PHE A 321
ILE A 310
ALA A 325
LEU A 307
LEU A 360
 None
 1.11A 4qynA-4g2pA:
undetectable		 4qynA-4g2pA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hka TRYPTOPHAN
2,3-DIOXYGENASE

(Drosophila
melanogaster) 		PF03301
(Trp_dioxygenase) 		5 PHE A 206
ILE A 363
TYR A 248
VAL A 247
LEU A 273
 None
 1.26A 4qynA-4hkaA:
undetectable		 4qynA-4hkaA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		5 ALA A 632
THR A 625
VAL A 660
LEU A 639
LEU A 605
 None
 1.01A 4qynA-4iugA:
undetectable		 4qynA-4iugA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nz5 DEACETYLASE DA1

(Vibrio cholerae) 		PF01522
(Polysacc_deac_1) 		5 ILE A  34
ALA A 322
VAL A  49
LEU A  36
LEU A 247
 None
 1.22A 4qynA-4nz5A:
undetectable		 4qynA-4nz5A:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oyy CUTINASE

(Humicola
insolens) 		PF01083
(Cutinase) 		5 ILE A 144
ALA A 114
VAL A  38
LEU A 131
LEU A  22
 None
 1.34A 4qynA-4oyyA:
undetectable		 4qynA-4oyyA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7l POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE

(Escherichia
coli) 		PF14883
(GHL13) 		5 ILE A 462
ALA A 454
VAL A 442
LEU A 521
LEU A 375
 None
 1.02A 4qynA-4p7lA:
undetectable		 4qynA-4p7lA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r5c LEUCINE RICH REPEAT
PROTEIN

(synthetic
construct) 		PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13516
(LRR_6)
PF13855
(LRR_8) 		5 PHE A 200
ILE A 216
ALA A 221
LEU A 192
LEU A 161
 None
 1.24A 4qynA-4r5cA:
undetectable		 4qynA-4r5cA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uis GAMMA-SECRETASE

(Homo sapiens) 		no annotation 5 ILE B 229
TYR B 181
VAL B 185
LEU B 232
LEU B 201
 None
 1.06A 4qynA-4uisB:
undetectable		 4qynA-4uisB:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4whb PHENYLUREA HYDROLASE
B

(Mycolicibacterium
brisbanense) 		no annotation 5 ALA E 243
TYR E 401
VAL E 397
LEU E 251
TRP E 296
 None
 1.34A 4qynA-4whbE:
undetectable		 4qynA-4whbE:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 3
ORIGIN RECOGNITION
COMPLEX SUBUNIT 5

(Drosophila
melanogaster;
Drosophila
melanogaster) 		PF07034
(ORC3_N)
PF13191
(AAA_16)
PF14630
(ORC5_C) 		5 PHE E 104
ILE E 123
THR C 184
LEU E  69
LEU E  96
 None
 1.32A 4qynA-4xgcE:
undetectable		 4qynA-4xgcE:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysj CALMODULIN-LIKE
DOMAIN PROTEIN
KINASE

(Eimeria tenella) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		5 ILE A 168
THR A 105
VAL A  42
LEU A 158
LEU A  80
 None
ADP  A 506 ( 4.6A)
ADP  A 506 (-4.3A)
ADP  A 506 (-4.7A)
None
 1.33A 4qynA-4ysjA:
undetectable		 4qynA-4ysjA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8y RAS-RELATED PROTEIN
SEC4

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		5 ILE A 156
TYR A 100
VAL A 102
LEU A 130
LEU A  36
 None
 0.88A 4qynA-4z8yA:
undetectable		 4qynA-4z8yA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zlv ORNITHINE
AMINOTRANSFERASE,
MITOCHONDRIAL,
PUTATIVE

(Toxoplasma
gondii) 		PF00202
(Aminotran_3) 		5 ALA A 212
THR A 195
LEU A 200
TRP A 172
LEU A 144
 None
 1.20A 4qynA-4zlvA:
undetectable		 4qynA-4zlvA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dlb CHAPERONE ESPG3

(Mycobacterium
marinum) 		PF14011
(ESX-1_EspG) 		5 ILE A 235
ALA A 270
THR A 124
VAL A 126
LEU A 151
 None
 1.32A 4qynA-5dlbA:
0.9		 4qynA-5dlbA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ej2 CARVEOL
DEHYDROGENASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		5 ILE A  42
ALA A  23
THR A 143
VAL A 148
LEU A 162
 None
 1.27A 4qynA-5ej2A:
undetectable		 4qynA-5ej2A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn3 PRESENILIN-1

(Homo sapiens) 		PF01080
(Presenilin) 		5 ILE B 229
TYR B 181
VAL B 185
LEU B 232
LEU B 201
 None
 1.22A 4qynA-5fn3B:
undetectable		 4qynA-5fn3B:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iq6 RNA DEPENDENT RNA
POLYMERASE

(Dengue virus) 		PF00972
(Flavi_NS5) 		5 ILE A 735
ALA A 775
TYR A 766
LEU A 734
LEU A 839
 None
 1.16A 4qynA-5iq6A:
undetectable		 4qynA-5iq6A:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k5m RNA DEPENDENT RNA
POLYMERASE

(Dengue virus) 		PF00972
(Flavi_NS5) 		5 ILE A 735
ALA A 775
TYR A 766
LEU A 734
LEU A 839
 None
 1.19A 4qynA-5k5mA:
undetectable		 4qynA-5k5mA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o8r L-LYSINE
6-MONOOXYGENASE
INVOLVED IN
DESFERRIOXAMINE
BIOSYNTHESIS

(Erwinia
amylovora) 		no annotation 5 PHE A 346
ILE A 350
VAL A  33
LEU A 152
TRP A 147
 FAD  A 501 (-4.5A)
None
None
None
None
 1.30A 4qynA-5o8rA:
undetectable		 4qynA-5o8rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ods CLATHRIN HEAVY CHAIN
1

(Mus musculus) 		no annotation 5 MET A 181
ILE A 194
ALA A 199
VAL A 186
LEU A 183
 None
 1.20A 4qynA-5odsA:
undetectable		 4qynA-5odsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogl UNDECAPRENYL-DIPHOSP
HOOLIGOSACCHARIDE--P
ROTEIN
GLYCOTRANSFERASE

(Campylobacter
lari) 		no annotation 5 ILE A 114
ALA A 385
THR A 377
TYR A 379
LEU A 160
 None
None
None
9UB  A 803 (-4.4A)
None
 1.27A 4qynA-5oglA:
undetectable		 4qynA-5oglA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u4s PUTATIVE SHORT CHAIN
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00106
(adh_short) 		5 ILE A   3
ALA A   8
VAL A 210
LEU A 203
LEU A  17
 None
None
None
None
NAP  A 300 (-4.5A)
 1.31A 4qynA-5u4sA:
undetectable		 4qynA-5u4sA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ujs UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Campylobacter
jejuni) 		PF00275
(EPSP_synthase) 		5 ILE A 413
ALA A 380
THR A 238
TYR A 239
LEU A 370
 None
 1.11A 4qynA-5ujsA:
undetectable		 4qynA-5ujsA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vws CYTOCHROME P450

(Thermobispora
bispora) 		PF00067
(p450) 		5 PHE A 333
ALA A 332
THR A 235
LEU A 267
LEU A 345
 HEM  A 401 (-3.8A)
HEM  A 401 (-4.1A)
HEM  A 401 ( 3.9A)
None
HEM  A 401 (-3.8A)
 1.03A 4qynA-5vwsA:
undetectable		 4qynA-5vwsA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wl7 ENGINEERED CHALCONE
ISOMERASE ANCCHI*

(unidentified) 		no annotation 5 PHE A 133
ILE A 160
THR A 188
VAL A  83
LEU A 116
 None
 1.20A 4qynA-5wl7A:
undetectable		 4qynA-5wl7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlg T CELL RECEPTOR
ALPHA VARIABLE
8D-2,HUMAN NKT TCR
ALPHA CHAIN CHIMERA

(Homo sapiens;
Mus musculus) 		no annotation 5 ILE D  75
ALA D  84
THR D  90
VAL D  31
LEU D  73
 None
 1.36A 4qynA-5wlgD:
undetectable		 4qynA-5wlgD:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a70 -

(-) 		no annotation 5 PHE B3888
ALA B3866
THR B3964
VAL B3967
LEU B3744
 None
 1.10A 4qynA-6a70B:
undetectable		 4qynA-6a70B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bfn INTERLEUKIN-1
RECEPTOR-ASSOCIATED
KINASE 1

(Homo sapiens) 		no annotation 5 ALA A 466
THR A 417
VAL A 413
LEU A 501
LEU A 518
 None
 1.27A 4qynA-6bfnA:
undetectable		 4qynA-6bfnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c33 5'-3' EXONUCLEASE

(Mycolicibacterium
smegmatis) 		no annotation 5 PHE A  39
ILE A 114
VAL A 141
LEU A  55
LEU A 166
 None
 1.31A 4qynA-6c33A:
undetectable		 4qynA-6c33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c33 5'-3' EXONUCLEASE

(Mycolicibacterium
smegmatis) 		no annotation 5 PHE A  39
ILE A 114
VAL A 141
LEU A  55
LEU A 170
 None
 1.20A 4qynA-6c33A:
undetectable		 4qynA-6c33A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d72 SPERMIDINE
N1-ACETYLTRANSFERASE

(Yersinia pestis) 		no annotation 5 ILE A  62
ALA A 102
VAL A 114
LEU A   9
LEU A 120
 None
 1.27A 4qynA-6d72A:
undetectable		 4qynA-6d72A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6deg BETA SLIDING CLAMP

(Bartonella
birtlesii) 		no annotation 5 PHE A 345
ILE A 334
ALA A 354
VAL A 277
LEU A 331
 None
 1.31A 4qynA-6degA:
undetectable		 4qynA-6degA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dk2 -

(-) 		no annotation 5 PHE A 195
TYR A 131
VAL A 132
LEU A 405
LEU A  42
 None
 1.33A 4qynA-6dk2A:
undetectable		 4qynA-6dk2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 HUNTINGTIN

(Homo sapiens) 		no annotation 5 ALA A2913
THR A2924
THR A2920
LEU A2595
LEU A2895
 None
 1.28A 4qynA-6ez8A:
undetectable		 4qynA-6ez8A:
undetectable