SIMILAR PATTERNS OF AMINO ACIDS FOR 4QWP_B_GCSB304
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1clx | XYLANASE A (Cellvibriojaponicus) |
PF00331(Glyco_hydro_10) | 3 | GLN A 279SER A 312ASP A 309 | None | 0.80A | 4qwpA-1clxA:0.04qwpB-1clxA:0.0 | 4qwpA-1clxA:20.744qwpB-1clxA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eys | PHOTOSYNTHETICREACTION CENTER (Thermochromatiumtepidum) |
PF00124(Photo_RC)PF02276(CytoC_RC) | 3 | GLN C 239SER L 166ASP L 163 | NoneBCL L 602 ( 4.3A)None | 0.89A | 4qwpA-1eysC:0.04qwpB-1eysC:0.0 | 4qwpA-1eysC:22.034qwpB-1eysC:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f5a | POLY(A) POLYMERASE (Bos taurus) |
PF01909(NTP_transf_2)PF04926(PAP_RNA-bind)PF04928(PAP_central) | 3 | GLN A 323SER A 307ASP A 308 | None | 0.87A | 4qwpA-1f5aA:0.04qwpB-1f5aA:0.0 | 4qwpA-1f5aA:18.424qwpB-1f5aA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flc | HAEMAGGLUTININ-ESTERASE-FUSIONGLYCOPROTEIN (Influenza Cvirus) |
PF02710(Hema_HEFG)PF03996(Hema_esterase)PF08720(Hema_stalk) | 3 | GLN A 8SER B 134ASP B 5 | None | 0.95A | 4qwpA-1flcA:0.04qwpB-1flcA:0.0 | 4qwpA-1flcA:20.654qwpB-1flcA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqo | PHOSPHOENOLPYRUVATECARBOXYLASE (Zea mays) |
PF00311(PEPcase) | 3 | GLN A 596SER A 286ASP A 454 | None | 0.85A | 4qwpA-1jqoA:0.14qwpB-1jqoA:0.0 | 4qwpA-1jqoA:15.714qwpB-1jqoA:15.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ms8 | TRANS-SIALIDASE (Trypanosomacruzi) |
PF13385(Laminin_G_3)PF13859(BNR_3) | 3 | GLN A 325SER A 393ASP A 389 | None | 0.95A | 4qwpA-1ms8A:0.04qwpB-1ms8A:0.0 | 4qwpA-1ms8A:18.314qwpB-1ms8A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nq6 | XYS1 (Streptomyceshalstedii) |
PF00331(Glyco_hydro_10) | 3 | GLN A 245SER A 275ASP A 272 | None | 0.68A | 4qwpA-1nq6A:0.04qwpB-1nq6A:0.0 | 4qwpA-1nq6A:22.984qwpB-1nq6A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q2e | EXOCELLOBIOHYDROLASEI (Trichodermareesei) |
PF00840(Glyco_hydro_7) | 3 | GLN A 175SER A 342ASP A 259 | GLC A 904 (-3.5A)NoneSGC A 902 ( 4.7A) | 0.67A | 4qwpA-1q2eA:undetectable4qwpB-1q2eA:undetectable | 4qwpA-1q2eA:20.844qwpB-1q2eA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgr | PROTEIN (IMPORTINALPHA-2 SUBUNIT)PROTEIN (IMPORTINBETA SUBUNIT) (Homo sapiens) |
PF01749(IBB)PF03810(IBN_N)PF13513(HEAT_EZ) | 3 | GLN B 46SER A 715ASP A 719 | None | 0.91A | 4qwpA-1qgrB:undetectable4qwpB-1qgrB:undetectable | 4qwpA-1qgrB:8.374qwpB-1qgrB:8.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rlm | PHOSPHATASE (Escherichiacoli) |
PF08282(Hydrolase_3) | 3 | GLN A 50SER A 178ASP A 11 | NoneGOL A 804 (-3.2A)GOL A 804 (-4.9A) | 0.80A | 4qwpA-1rlmA:undetectable4qwpB-1rlmA:undetectable | 4qwpA-1rlmA:20.004qwpB-1rlmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sp8 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Zea mays) |
PF00903(Glyoxalase) | 3 | GLN A 405SER A 215ASP A 307 | None | 0.86A | 4qwpA-1sp8A:undetectable4qwpB-1sp8A:undetectable | 4qwpA-1sp8A:21.314qwpB-1sp8A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxj | ACTIVATOR 1 37 KDASUBUNIT (Saccharomycescerevisiae) |
PF00004(AAA)PF08542(Rep_fac_C) | 3 | GLN B 177SER B 21ASP B 22 | None | 0.96A | 4qwpA-1sxjB:2.14qwpB-1sxjB:2.1 | 4qwpA-1sxjB:22.464qwpB-1sxjB:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szn | ALPHA-GALACTOSIDASE (Trichodermareesei) |
PF16499(Melibiase_2) | 3 | GLN A 207SER A 178ASP A 142 | NoneNoneGOL A 901 (-3.7A) | 0.93A | 4qwpA-1sznA:undetectable4qwpB-1sznA:undetectable | 4qwpA-1sznA:19.904qwpB-1sznA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1thg | LIPASE 2 (Galactomycescandidus) |
PF00135(COesterase) | 3 | GLN A 502SER A 487ASP A 493 | None | 0.91A | 4qwpA-1thgA:undetectable4qwpB-1thgA:undetectable | 4qwpA-1thgA:19.564qwpB-1thgA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v6y | ENDO-1,4-BETA-D-XYLANASE ANDENDO-1,4-BETA-XYLANASE B (Cellulomonasfimi;Streptomycesolivaceoviridis) |
PF00331(Glyco_hydro_10) | 3 | GLN A 252SER A 282ASP A 279 | None | 0.64A | 4qwpA-1v6yA:undetectable4qwpB-1v6yA:undetectable | 4qwpA-1v6yA:21.414qwpB-1v6yA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbr | ENDO-1,4-BETA-XYLANASE B (Thermotogamaritima) |
PF00331(Glyco_hydro_10) | 3 | GLN A 771SER A 801ASP A 798 | None | 0.71A | 4qwpA-1vbrA:undetectable4qwpB-1vbrA:undetectable | 4qwpA-1vbrA:22.394qwpB-1vbrA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zq1 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT D (Pyrococcusabyssi) |
PF00710(Asparaginase) | 3 | GLN A 205SER A 146ASP A 179 | NoneASP A1000 (-2.2A)ASP A1000 (-3.6A) | 0.75A | 4qwpA-1zq1A:undetectable4qwpB-1zq1A:undetectable | 4qwpA-1zq1A:20.054qwpB-1zq1A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b9b | FUSION GLYCOPROTEINF0 (Mammalianrubulavirus 5) |
PF00523(Fusion_gly) | 3 | GLN A 169SER A 59ASP A 58 | None | 0.76A | 4qwpA-2b9bA:undetectable4qwpB-2b9bA:undetectable | 4qwpA-2b9bA:20.554qwpB-2b9bA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cqu | PEROXISOMALD3,D2-ENOYL-COAISOMERASE (Homo sapiens) |
PF00887(ACBP) | 3 | GLN A 86SER A 23ASP A 19 | None | 0.90A | 4qwpA-2cquA:undetectable4qwpB-2cquA:undetectable | 4qwpA-2cquA:19.124qwpB-2cquA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dep | THERMOSTABLECELLOXYLANASE ([Clostridium]stercorarium) |
PF00331(Glyco_hydro_10) | 3 | GLN A 319SER A 350ASP A 347 | None | 0.71A | 4qwpA-2depA:undetectable4qwpB-2depA:undetectable | 4qwpA-2depA:21.024qwpB-2depA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpy | FLAGELLUM-SPECIFICATP SYNTHASE (Salmonellaenterica) |
PF00006(ATP-synt_ab) | 3 | GLN A 399SER A 354ASP A 367 | None | 0.64A | 4qwpA-2dpyA:undetectable4qwpB-2dpyA:undetectable | 4qwpA-2dpyA:22.154qwpB-2dpyA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2his | CELLULOMONAS FIMIFAMILY 10BETA-1,4-GLYCANASE (Cellulomonasfimi) |
PF00331(Glyco_hydro_10) | 3 | GLN A 250SER A 280ASP A 277 | None | 0.62A | 4qwpA-2hisA:undetectable4qwpB-2hisA:undetectable | 4qwpA-2hisA:23.224qwpB-2hisA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5r | GLUTATHIONEPEROXIDASE 5 (Populustrichocarpa xPopulusdeltoides) |
PF00255(GSHPx) | 3 | GLN A 145SER A 6ASP A 14 | None | 0.83A | 4qwpA-2p5rA:undetectable4qwpB-2p5rA:undetectable | 4qwpA-2p5rA:20.474qwpB-2p5rA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vmf | BETA-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2) | 3 | GLN A 646SER A 589ASP A 199 | NoneNoneMVL A1865 ( 2.9A) | 0.90A | 4qwpA-2vmfA:undetectable4qwpB-2vmfA:undetectable | 4qwpA-2vmfA:14.574qwpB-2vmfA:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w0m | SSO2452 (Sulfolobussolfataricus) |
PF06745(ATPase) | 3 | GLN A 166SER A 40ASP A 130 | None | 0.81A | 4qwpA-2w0mA:1.14qwpB-2w0mA:undetectable | 4qwpA-2w0mA:20.234qwpB-2w0mA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhg | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF07632(DUF1593) | 3 | GLN A 684SER A 542ASP A 539 | CA A1934 ( 4.3A)None CA A1934 (-2.2A) | 0.86A | 4qwpA-2yhgA:undetectable4qwpB-2yhgA:undetectable | 4qwpA-2yhgA:21.794qwpB-2yhgA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yok | EXOGLUCANASE 1 (Trichodermaharzianum) |
PF00840(Glyco_hydro_7) | 3 | GLN A 188SER A 355ASP A 272 | NoneNonePEG A1445 (-3.9A) | 0.82A | 4qwpA-2yokA:undetectable4qwpB-2yokA:undetectable | 4qwpA-2yokA:18.854qwpB-2yokA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a1y | ACIDIC RIBOSOMALPROTEIN P0 (Pyrococcushorikoshii) |
PF00466(Ribosomal_L10) | 3 | GLN G 104SER G 32ASP G 190 | None | 0.90A | 4qwpA-3a1yG:undetectable4qwpB-3a1yG:undetectable | 4qwpA-3a1yG:23.084qwpB-3a1yG:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axi | OLIGO-1,6-GLUCOSIDASE IMA1 (Saccharomycescerevisiae) |
PF00128(Alpha-amylase) | 3 | GLN A 279SER A 241ASP A 242 | None | 0.88A | 4qwpA-3axiA:undetectable4qwpB-3axiA:undetectable | 4qwpA-3axiA:16.984qwpB-3axiA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c9f | 5'-NUCLEOTIDASE (Candidaalbicans) |
PF00149(Metallophos) | 3 | GLN A 232SER A 262ASP A 259 | None | 0.86A | 4qwpA-3c9fA:undetectable4qwpB-3c9fA:undetectable | 4qwpA-3c9fA:16.854qwpB-3c9fA:16.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7w | D-ALANINE--POLY(PHOSPHORIBITOL) LIGASESUBUNIT 1 (Bacillussubtilis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 3 | GLN A 375SER A 170ASP A 326 | None | 0.89A | 4qwpA-3e7wA:undetectable4qwpB-3e7wA:undetectable | 4qwpA-3e7wA:18.574qwpB-3e7wA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3elu | METHYLTRANSFERASE (Wesselsbronvirus) |
PF00972(Flavi_NS5)PF01728(FtsJ) | 3 | GLN A 284SER A 130ASP A 128 | None | 0.93A | 4qwpA-3eluA:undetectable4qwpB-3eluA:undetectable | 4qwpA-3eluA:22.684qwpB-3eluA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqa | GLUCOAMYLASE (Aspergillusniger) |
PF00723(Glyco_hydro_15) | 3 | GLN A 433SER A 64ASP A 438 | NoneNoneNAG A 551 (-3.8A) | 0.93A | 4qwpA-3eqaA:undetectable4qwpB-3eqaA:undetectable | 4qwpA-3eqaA:22.464qwpB-3eqaA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7r | PUTATIVETRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF00440(TetR_N) | 3 | GLN A 76SER A 104ASP A 100 | IOD A 203 (-3.9A)NoneNone | 0.81A | 4qwpA-3g7rA:undetectable4qwpB-3g7rA:undetectable | 4qwpA-3g7rA:24.154qwpB-3g7rA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hsy | GLUTAMATE RECEPTOR 2 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 3 | GLN A 106SER A 138ASP A 98 | None | 0.73A | 4qwpA-3hsyA:undetectable4qwpB-3hsyA:undetectable | 4qwpA-3hsyA:22.754qwpB-3hsyA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hzs | MONOFUNCTIONALGLYCOSYLTRANSFERASE (Staphylococcusaureus) |
PF00912(Transgly) | 3 | GLN A 251SER A 124ASP A 127 | None | 0.82A | 4qwpA-3hzsA:undetectable4qwpB-3hzsA:2.6 | 4qwpA-3hzsA:18.474qwpB-3hzsA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mvp | TETR/ACRRTRANSCRIPTIONALREGULATOR (Streptococcusmutans) |
PF00440(TetR_N) | 3 | GLN A 138SER A 69ASP A 72 | None | 0.95A | 4qwpA-3mvpA:undetectable4qwpB-3mvpA:undetectable | 4qwpA-3mvpA:20.864qwpB-3mvpA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oaa | ATP SYNTHASE SUBUNITBETA (Escherichiacoli) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 3 | GLN D 368SER D 322ASP D 335 | None | 0.90A | 4qwpA-3oaaD:undetectable4qwpB-3oaaD:undetectable | 4qwpA-3oaaD:21.754qwpB-3oaaD:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE BETA-SUBUNIT (Komagataellapastoris) |
PF00365(PFK) | 3 | GLN B 777SER B 936ASP B 933 | None | 0.92A | 4qwpA-3opyB:undetectable4qwpB-3opyB:undetectable | 4qwpA-3opyB:13.664qwpB-3opyB:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozy | PUTATIVE MANDELATERACEMASE (Bordetellabronchiseptica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | GLN A 275SER A 145ASP A 201 | NoneNone MG A 390 (-2.8A) | 0.78A | 4qwpA-3ozyA:undetectable4qwpB-3ozyA:undetectable | 4qwpA-3ozyA:22.254qwpB-3ozyA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q1y | LIN2199 PROTEIN (Listeriainnocua) |
PF00294(PfkB) | 3 | GLN A 115SER A 148ASP A 149 | None | 0.87A | 4qwpA-3q1yA:undetectable4qwpB-3q1yA:0.4 | 4qwpA-3q1yA:23.694qwpB-3q1yA:23.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q2i | DEHYDROGENASE (Chromobacteriumviolaceum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 3 | GLN A 189SER A 83ASP A 182 | HP7 A 550 (-4.8A)NAI A 500 (-2.7A)None | 0.58A | 4qwpA-3q2iA:undetectable4qwpB-3q2iA:undetectable | 4qwpA-3q2iA:21.754qwpB-3q2iA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q2k | OXIDOREDUCTASE (Bordetellapertussis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 3 | GLN A 188SER A 82ASP A 181 | HP7 A 550 (-3.9A)NAI A 500 (-2.7A)None | 0.64A | 4qwpA-3q2kA:undetectable4qwpB-3q2kA:undetectable | 4qwpA-3q2kA:21.744qwpB-3q2kA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t05 | PYRUVATE KINASE (Staphylococcusaureus) |
PF00224(PK)PF00391(PEP-utilizers)PF02887(PK_C) | 3 | GLN A 259SER A 295ASP A 296 | None | 0.93A | 4qwpA-3t05A:undetectable4qwpB-3t05A:undetectable | 4qwpA-3t05A:18.704qwpB-3t05A:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t57 | UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASEDOMAIN-CONTAININGPROTEIN (Arabidopsisthaliana) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 3 | GLN A 216SER A 158ASP A 129 | None | 0.96A | 4qwpA-3t57A:undetectable4qwpB-3t57A:undetectable | 4qwpA-3t57A:18.304qwpB-3t57A:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsr | RIBONUCLEASEINHIBITORRIBONUCLEASEPANCREATIC (Mus musculus) |
PF00074(RnaseA)PF13516(LRR_6) | 3 | GLN A 12SER E 401ASP E 431 | None | 0.60A | 4qwpA-3tsrA:undetectable4qwpB-3tsrA:undetectable | 4qwpA-3tsrA:17.414qwpB-3tsrA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujg | SERINE/THREONINE-PROTEIN KINASE SRK2E (Arabidopsisthaliana) |
PF00069(Pkinase) | 3 | GLN A 135SER A 166ASP A 140 | None | 0.92A | 4qwpA-3ujgA:undetectable4qwpB-3ujgA:undetectable | 4qwpA-3ujgA:21.514qwpB-3ujgA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w25 | GLYCOSIDE HYDROLASEFAMILY 10 (Thermoanaerobacteriumsaccharolyticum) |
PF00331(Glyco_hydro_10) | 3 | GLN A 268SER A 299ASP A 296 | None | 0.72A | 4qwpA-3w25A:undetectable4qwpB-3w25A:undetectable | 4qwpA-3w25A:23.454qwpB-3w25A:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wuf | ENDO-1,4-BETA-XYLANASE A (Streptomycessp.) |
PF00331(Glyco_hydro_10) | 3 | GLN A 288SER A 318ASP A 315 | None | 0.75A | 4qwpA-3wufA:undetectable4qwpB-3wufA:undetectable | 4qwpA-3wufA:24.304qwpB-3wufA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cak | INTEGRIN BETA-3 (Homo sapiens) |
PF00362(Integrin_beta)PF07965(Integrin_B_tail)PF07974(EGF_2)PF17205(PSI_integrin) | 3 | GLN B 342SER B 74ASP B 109 | None | 0.76A | 4qwpA-4cakB:undetectable4qwpB-4cakB:undetectable | 4qwpA-4cakB:16.184qwpB-4cakB:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dni | FUSION PROTEIN OFRNA-EDITING COMPLEXPROTEINS MP42 ANDMP18 (Trypanosomabrucei) |
PF00436(SSB) | 3 | GLN A 257SER A 79ASP A 84 | None | 0.76A | 4qwpA-4dniA:undetectable4qwpB-4dniA:undetectable | 4qwpA-4dniA:20.364qwpB-4dniA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f8x | ENDO-1,4-BETA-XYLANASE (Penicilliumcanescens) |
PF00331(Glyco_hydro_10) | 3 | GLN A 289SER A 320ASP A 317 | None | 0.81A | 4qwpA-4f8xA:undetectable4qwpB-4f8xA:undetectable | 4qwpA-4f8xA:22.164qwpB-4f8xA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ffl | PYLC (Methanosarcinabarkeri) |
PF02655(ATP-grasp_3) | 3 | GLN A 247SER A 138ASP A 194 | CO3 A 907 (-4.1A)ADP A 902 (-3.2A)None | 0.91A | 4qwpA-4fflA:undetectable4qwpB-4fflA:undetectable | 4qwpA-4fflA:21.584qwpB-4fflA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmw | RNA(GUANINE-9-)-METHYLTRANSFERASEDOMAIN-CONTAININGPROTEIN 2 (Homo sapiens) |
PF01746(tRNA_m1G_MT) | 3 | GLN A 221SER A 145ASP A 106 | None | 0.65A | 4qwpA-4fmwA:undetectable4qwpB-4fmwA:undetectable | 4qwpA-4fmwA:19.254qwpB-4fmwA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzv | PUTATIVEMETHYLTRANSFERASENSUN4 (Homo sapiens) |
PF01189(Methyltr_RsmB-F) | 3 | GLN A 316SER A 264ASP A 261 | None | 0.94A | 4qwpA-4fzvA:undetectable4qwpB-4fzvA:undetectable | 4qwpA-4fzvA:21.944qwpB-4fzvA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl8 | OLIGOPEPTIDE ABCTRANSPORTER OPPAIV (Borreliellaburgdorferi) |
PF00496(SBP_bac_5) | 3 | GLN A 181SER A 429ASP A 431 | None | 0.91A | 4qwpA-4gl8A:undetectable4qwpB-4gl8A:undetectable | 4qwpA-4gl8A:18.324qwpB-4gl8A:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hu8 | GH10 XYLANASE (Globitermesbrachycerastes) |
PF00331(Glyco_hydro_10)PF02368(Big_2) | 3 | GLN A 406SER A 437ASP A 434 | None | 0.71A | 4qwpA-4hu8A:undetectable4qwpB-4hu8A:undetectable | 4qwpA-4hu8A:21.994qwpB-4hu8A:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i5s | VICK-LIKE PROTEINPUTATIVE HISTIDINEKINASE COVS (Streptococcusmutans) |
PF00512(HisKA)PF00989(PAS)PF02518(HATPase_c) | 3 | GLN A 330SER A 275ASP A 263 | None | 0.93A | 4qwpA-4i5sA:undetectable4qwpB-4i5sA:undetectable | 4qwpA-4i5sA:18.104qwpB-4i5sA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irl | MALTOSE-BINDINGPERIPLASMIC PROTEIN,NOVEL PROTEINSIMILAR TOVERTEBRATE GUANYLATEBINDING PROTEINFAMILY (Danio rerio;Escherichiacoli) |
PF00619(CARD)PF13416(SBP_bac_8) | 3 | GLN A 336SER A 74ASP A 380 | None | 0.78A | 4qwpA-4irlA:undetectable4qwpB-4irlA:undetectable | 4qwpA-4irlA:21.414qwpB-4irlA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7c | AMINOPEPTIDASE C (Lactobacillusrhamnosus) |
PF03051(Peptidase_C1_2) | 3 | GLN A 261SER A 146ASP A 143 | None | 0.72A | 4qwpA-4k7cA:0.34qwpB-4k7cA:undetectable | 4qwpA-4k7cA:18.674qwpB-4k7cA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq9 | RIBOSE ABCTRANSPORTER,SUBSTRATE BINDINGPROTEIN (Conexibacterwoesei) |
PF13407(Peripla_BP_4) | 3 | GLN A 286SER A 111ASP A 137 | GOL A 502 (-3.4A)NoneGOL A 502 (-2.8A) | 0.81A | 4qwpA-4kq9A:undetectable4qwpB-4kq9A:undetectable | 4qwpA-4kq9A:27.244qwpB-4kq9A:27.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lvo | SUBTILISIN-LIKESERINE PROTEASE (Plasmodiumfalciparum) |
PF00082(Peptidase_S8) | 3 | GLN A 355SER A 621ASP A 450 | None | 0.88A | 4qwpA-4lvoA:undetectable4qwpB-4lvoA:0.8 | 4qwpA-4lvoA:20.554qwpB-4lvoA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lxr | PROTEIN TOLL (Drosophilamelanogaster) |
PF00560(LRR_1)PF01462(LRRNT)PF13306(LRR_5)PF13855(LRR_8) | 3 | GLN A 462SER A 511ASP A 516 | None | 0.76A | 4qwpA-4lxrA:undetectable4qwpB-4lxrA:undetectable | 4qwpA-4lxrA:14.344qwpB-4lxrA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2g | L-ARGININEBETA-HYDROXYLASE (Streptomyceslavendulae) |
PF02668(TauD) | 3 | GLN A 123SER A 164ASP A 157 | None | 0.91A | 4qwpA-4m2gA:undetectable4qwpB-4m2gA:undetectable | 4qwpA-4m2gA:22.594qwpB-4m2gA:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nph | PROBABLE SECRETIONSYSTEM APPARATUS ATPSYNTHASE SSAN (Salmonellaenterica) |
PF00006(ATP-synt_ab) | 3 | GLN A 377SER A 332ASP A 345 | None | 0.92A | 4qwpA-4nphA:undetectable4qwpB-4nphA:undetectable | 4qwpA-4nphA:22.254qwpB-4nphA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ol9 | PUTATIVE2-DEHYDROPANTOATE2-REDUCTASE (Mycobacteriumtuberculosis) |
PF02558(ApbA)PF08546(ApbA_C) | 3 | GLN A 77SER A 246ASP A 250 | NAP A 301 (-3.1A)OXM A 302 ( 2.7A)NAP A 301 ( 4.8A) | 0.95A | 4qwpA-4ol9A:undetectable4qwpB-4ol9A:undetectable | 4qwpA-4ol9A:23.124qwpB-4ol9A:23.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oud | TYROSYL-TRNASYNTHETASE (Escherichiacoli) |
PF00579(tRNA-synt_1b) | 3 | GLN B 300SER B 293ASP B 290 | GLN B 300 ( 0.6A)SER B 293 ( 0.0A)ASP B 290 ( 0.6A) | 0.96A | 4qwpA-4oudB:undetectable4qwpB-4oudB:undetectable | 4qwpA-4oudB:20.154qwpB-4oudB:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p3m | SERINEHYDROXYMETHYLTRANSFERASE (Psychromonasingrahamii) |
PF00464(SHMT) | 3 | GLN A 326SER A 360ASP A 322 | None | 0.94A | 4qwpA-4p3mA:undetectable4qwpB-4p3mA:undetectable | 4qwpA-4p3mA:23.964qwpB-4p3mA:23.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7a | HISTONE-BINDINGPROTEIN RBBP4 (Homo sapiens) |
PF00400(WD40)PF12265(CAF1C_H4-bd) | 3 | GLN B 322SER B 234ASP B 232 | None | 0.94A | 4qwpA-4r7aB:undetectable4qwpB-4r7aB:undetectable | 4qwpA-4r7aB:18.944qwpB-4r7aB:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ric | FANCONI-ASSOCIATEDNUCLEASE 1 (Homo sapiens) |
PF08774(VRR_NUC) | 3 | GLN A 568SER A 617ASP A 614 | None | 0.95A | 4qwpA-4ricA:undetectable4qwpB-4ricA:undetectable | 4qwpA-4ricA:16.774qwpB-4ricA:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr2 | SUBTILISIN-LIKE 1SERINE PROTEASE (Plasmodiumvivax) |
PF00082(Peptidase_S8) | 3 | GLN A 299SER A 564ASP A 394 | PO4 A 806 ( 4.2A)NoneNone | 0.80A | 4qwpA-4tr2A:0.34qwpB-4tr2A:0.4 | 4qwpA-4tr2A:17.244qwpB-4tr2A:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u0p | LIPOYL SYNTHASE 2 (Thermosynechococcuselongatus) |
PF04055(Radical_SAM) | 3 | GLN B 114SER B 188ASP B 141 | None | 0.86A | 4qwpA-4u0pB:undetectable4qwpB-4u0pB:undetectable | 4qwpA-4u0pB:24.204qwpB-4u0pB:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wt7 | ABC TRANSPORTERSUBSTRATE BINDINGPROTEIN (RIBOSE) (Agrobacteriumvitis) |
PF13407(Peripla_BP_4) | 3 | GLN A 326SER A 164ASP A 165 | None | 0.93A | 4qwpA-4wt7A:undetectable4qwpB-4wt7A:undetectable | 4qwpA-4wt7A:22.464qwpB-4wt7A:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ww3 | RHODOPSIN (Todarodespacificus) |
PF00001(7tm_1) | 3 | GLN A 269SER A 84ASP A 80 | None | 0.96A | 4qwpA-4ww3A:0.64qwpB-4ww3A:undetectable | 4qwpA-4ww3A:20.854qwpB-4ww3A:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xx6 | BETA-XYLANASE (Gloeophyllumtrabeum) |
PF00331(Glyco_hydro_10) | 3 | GLN A 282SER A 313ASP A 310 | None | 0.75A | 4qwpA-4xx6A:undetectable4qwpB-4xx6A:undetectable | 4qwpA-4xx6A:22.514qwpB-4xx6A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yh7 | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE DELTA (Mus musculus) |
PF00041(fn3)PF07679(I-set)PF13927(Ig_3) | 3 | GLN A 53SER A 176ASP A 174 | None | 0.88A | 4qwpA-4yh7A:undetectable4qwpB-4yh7A:undetectable | 4qwpA-4yh7A:16.244qwpB-4yh7A:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zet | C-TYPE LECTIN DOMAINFAMILY 4 MEMBER C (Homo sapiens) |
PF00059(Lectin_C) | 3 | GLN A 158SER A 112ASP A 117 | None | 0.86A | 4qwpA-4zetA:undetectable4qwpB-4zetA:undetectable | 4qwpA-4zetA:18.334qwpB-4zetA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zkt | BONTOXILYSIN A (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07951(Toxin_R_bind_C)PF07952(Toxin_trans)PF07953(Toxin_R_bind_N) | 3 | GLN A 749SER A 849ASP A1051 | None | 0.96A | 4qwpA-4zktA:0.84qwpB-4zktA:0.7 | 4qwpA-4zktA:11.414qwpB-4zktA:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzp | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Dictyosteliumpurpureum) |
PF00840(Glyco_hydro_7) | 3 | GLN A 174SER A 348ASP A 258 | None | 0.75A | 4qwpA-4zzpA:undetectable4qwpB-4zzpA:undetectable | 4qwpA-4zzpA:19.464qwpB-4zzpA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zzq | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Dictyosteliumdiscoideum) |
PF00840(Glyco_hydro_7) | 3 | GLN A 174SER A 348ASP A 258 | None | 0.95A | 4qwpA-4zzqA:undetectable4qwpB-4zzqA:undetectable | 4qwpA-4zzqA:19.634qwpB-4zzqA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a0z | CHOLINETRIMETHYLAMINE LYASE (Klebsiellapneumoniae) |
PF01228(Gly_radical)PF02901(PFL-like) | 3 | GLN A 685SER A1067ASP A 747 | None | 0.69A | 4qwpA-5a0zA:undetectable4qwpB-5a0zA:undetectable | 4qwpA-5a0zA:16.754qwpB-5a0zA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffq | SHUY-LIKE PROTEIN (Escherichiacoli) |
PF13460(NAD_binding_10) | 3 | GLN A 139SER A 112ASP A 111 | None | 0.78A | 4qwpA-5ffqA:undetectable4qwpB-5ffqA:undetectable | 4qwpA-5ffqA:24.344qwpB-5ffqA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h07 | POLYUBIQUITIN-C (Homo sapiens) |
PF00240(ubiquitin) | 3 | GLN A 131SER A 220ASP A 221 | None | 0.85A | 4qwpA-5h07A:undetectable4qwpB-5h07A:undetectable | 4qwpA-5h07A:23.994qwpB-5h07A:23.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hc8 | PRENYLTRANSFERENCEFOR PROTEIN (Lavandulalanata) |
PF01255(Prenyltransf) | 3 | GLN A 94SER A 145ASP A 141 | None | 0.70A | 4qwpA-5hc8A:1.64qwpB-5hc8A:1.6 | 4qwpA-5hc8A:21.504qwpB-5hc8A:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5inf | CARBOXYL TRANSFERASE (Streptomycesambofaciens) |
PF01039(Carboxyl_trans) | 3 | GLN A 253SER A 63ASP A 60 | None | 0.95A | 4qwpA-5infA:undetectable4qwpB-5infA:undetectable | 4qwpA-5infA:19.054qwpB-5infA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0k | BETA-XYLANASE (Cellulomonasflavigena) |
no annotation | 3 | GLN A 238SER A 272ASP A 269 | None | 0.84A | 4qwpA-5m0kA:undetectable4qwpB-5m0kA:undetectable | 4qwpA-5m0kA:24.584qwpB-5m0kA:24.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m0k | BETA-XYLANASE (Cellulomonasflavigena) |
no annotation | 3 | GLN A 242SER A 272ASP A 269 | None | 0.84A | 4qwpA-5m0kA:undetectable4qwpB-5m0kA:undetectable | 4qwpA-5m0kA:24.584qwpB-5m0kA:24.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mlv | - (-) |
no annotation | 3 | GLN G 165SER G 207ASP G 205 | None | 0.94A | 4qwpA-5mlvG:undetectable4qwpB-5mlvG:undetectable | 4qwpA-5mlvG:undetectable4qwpB-5mlvG:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8o | DNA HELICASE I (Escherichiacoli) |
PF07057(TraI)PF08751(TrwC)PF13604(AAA_30) | 3 | GLN A 687SER A 665ASP A 667 | None | 0.89A | 4qwpA-5n8oA:0.54qwpB-5n8oA:undetectable | 4qwpA-5n8oA:10.964qwpB-5n8oA:10.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o5d | GLUCANASE (Trichodermaatroviride) |
no annotation | 3 | GLN A 175SER A 342ASP A 259 | BTB A 604 (-3.8A)NoneNone | 0.76A | 4qwpA-5o5dA:undetectable4qwpB-5o5dA:undetectable | 4qwpA-5o5dA:15.904qwpB-5o5dA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5och | - (-) |
no annotation | 3 | GLN B 324SER B 253ASP B 258 | None | 0.93A | 4qwpA-5ochB:undetectable4qwpB-5ochB:undetectable | 4qwpA-5ochB:undetectable4qwpB-5ochB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofk | GLYCOSIDE HYDROLASEFAMILY 48 (Caldicellulosiruptorbescii) |
PF00331(Glyco_hydro_10) | 3 | GLN A 273SER A 304ASP A 301 | None | 0.73A | 4qwpA-5ofkA:undetectable4qwpB-5ofkA:undetectable | 4qwpA-5ofkA:20.904qwpB-5ofkA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8v | PUTATIVEUNCHARACTERIZEDPROTEIN (Chaetomiumthermophilum) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 3 | GLN A 976SER A 903ASP A 971 | None | 0.90A | 4qwpA-5t8vA:undetectable4qwpB-5t8vA:undetectable | 4qwpA-5t8vA:11.044qwpB-5t8vA:11.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xs1 | HYPERGLYCEMICHORMONE-LIKE PEPTIDE (Scylla olivacea) |
no annotation | 3 | GLN A 1SER A 6ASP A 4 | None | 0.95A | 4qwpA-5xs1A:undetectable4qwpB-5xs1A:undetectable | 4qwpA-5xs1A:13.604qwpB-5xs1A:13.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xzu | BETA-XYLANASE (Bispora sp.MEY-1) |
no annotation | 3 | GLN A 266SER A 296ASP A 293 | None | 0.82A | 4qwpA-5xzuA:undetectable4qwpB-5xzuA:undetectable | 4qwpA-5xzuA:16.194qwpB-5xzuA:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cgm | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Bacillussubtilis) |
no annotation | 3 | GLN A 361SER A 204ASP A 315 | None | 0.82A | 4qwpA-6cgmA:undetectable4qwpB-6cgmA:undetectable | 4qwpA-6cgmA:17.984qwpB-6cgmA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1 (Saccharomycescerevisiae) |
no annotation | 3 | GLN A 688SER A 388ASP A 390 | None | 0.85A | 4qwpA-6f42A:undetectable4qwpB-6f42A:undetectable | 4qwpA-6f42A:17.894qwpB-6f42A:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6frv | GLUCOAMYLASE (Aspergillusniger) |
no annotation | 3 | GLN A 433SER A 64ASP A 438 | NoneNoneNAG A 703 (-3.1A) | 0.88A | 4qwpA-6frvA:undetectable4qwpB-6frvA:undetectable | 4qwpA-6frvA:17.344qwpB-6frvA:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fx6 | - (-) |
no annotation | 3 | GLN A 96SER A 131ASP A 127 | None | 0.80A | 4qwpA-6fx6A:undetectable4qwpB-6fx6A:undetectable | 4qwpA-6fx6A:undetectable4qwpB-6fx6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g45 | PUTATIVE MAJORCAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 3 | GLN A 127SER A 336ASP A 347 | None | 0.88A | 4qwpA-6g45A:undetectable4qwpB-6g45A:undetectable | 4qwpA-6g45A:14.684qwpB-6g45A:14.68 |