SIMILAR PATTERNS OF AMINO ACIDS FOR 4QOP_C_HQEC503
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1a4e | CATALASE A (Saccharomycescerevisiae) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | ASP A 123PRO A 124PHE A 149LEU A 196PHE A 197 | None | 0.36A | 4qopC-1a4eA:53.3 | 4qopC-1a4eA:41.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bx0 | PROTEIN(FERREDOXIN:NADP+OXIDOREDUCTASE) (Spinaciaoleracea) |
PF00175(NAD_binding_1) | 4 | PHE A 62LEU A 147LEU A 136PHE A 135 | None | 0.93A | 4qopC-1bx0A:0.3 | 4qopC-1bx0A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwv | INVASIN (Yersiniapseudotuberculosis) |
PF02369(Big_1)PF07979(Intimin_C)PF09134(Invasin_D3) | 4 | PRO A 697PHE A 723LEU A 739PHE A 732 | None | 0.95A | 4qopC-1cwvA:undetectable | 4qopC-1cwvA:22.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dgf | CATALASE (Homo sapiens) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | ASP A 128PRO A 129PHE A 154LEU A 199PHE A 200 | ACT A5000 ( 4.9A)NoneNoneNoneNone | 0.35A | 4qopC-1dgfA:56.3 | 4qopC-1dgfA:46.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dmu | BGLI RESTRICTIONENDONUCLEASE (Bacillussubtilis) |
PF14562(Endonuc_BglI) | 4 | ILE A 200PRO A 208PHE A 133LEU A 20 | None | 0.92A | 4qopC-1dmuA:undetectable | 4qopC-1dmuA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnz | GSI-B4 ISOLECTIN (Griffoniasimplicifolia) |
PF00139(Lectin_legB) | 4 | ILE A 145PHE A 77LEU A 188LEU A 79 | None | 0.86A | 4qopC-1gnzA:undetectable | 4qopC-1gnzA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gxs | P-(S)-HYDROXYMANDELONITRILE LYASE CHAINA (Sorghum bicolor) |
PF00450(Peptidase_S10) | 4 | PHE A 141LEU A 56LEU A 137PHE A 136 | None | 0.91A | 4qopC-1gxsA:undetectable | 4qopC-1gxsA:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k5o | CPI-17 (Sus scrofa) |
PF05361(PP1_inhibitor) | 4 | ASP A 39PHE A 73LEU A 26TYR A 30 | None | 0.88A | 4qopC-1k5oA:undetectable | 4qopC-1k5oA:11.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ka9 | IMIDAZOLE GLYCEROLPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF00117(GATase) | 4 | PRO H 175PHE H 189TYR H 196LEU H 166 | None | 0.75A | 4qopC-1ka9H:undetectable | 4qopC-1ka9H:18.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m7s | CATALASE (Pseudomonassyringae) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | ASP A 130PRO A 131PHE A 156LEU A 201 | None | 0.60A | 4qopC-1m7sA:55.9 | 4qopC-1m7sA:49.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ny5 | TRANSCRIPTIONALREGULATOR (NTRCFAMILY) (Aquifexaeolicus) |
PF00072(Response_reg)PF00158(Sigma54_activat) | 4 | ILE A 240PHE A 204LEU A 243PHE A 227 | None | 0.89A | 4qopC-1ny5A:undetectable | 4qopC-1ny5A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pv5 | HYPOTHETICAL PROTEINYWQG (Bacillussubtilis) |
PF09234(DUF1963) | 4 | ILE A 66PRO A 78PHE A 251LEU A 246 | None | 0.91A | 4qopC-1pv5A:undetectable | 4qopC-1pv5A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1p | EPITHELIAL-CADHERIN (Mus musculus) |
PF00028(Cadherin) | 4 | ILE A 7PHE A 51LEU A 21LEU A 66 | None | 0.94A | 4qopC-1q1pA:undetectable | 4qopC-1q1pA:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q8i | DNA POLYMERASE II (Escherichiacoli) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | ASP A 434PRO A 435PHE A 373LEU A 503 | None | 0.83A | 4qopC-1q8iA:undetectable | 4qopC-1q8iA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qyi | HYPOTHETICAL PROTEIN (Staphylococcusaureus) |
PF13242(Hydrolase_like) | 4 | ILE A 101PHE A 167LEU A 159LEU A 89 | None | 0.88A | 4qopC-1qyiA:undetectable | 4qopC-1qyiA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r8g | HYPOTHETICAL PROTEINYBDK (Escherichiacoli) |
PF04107(GCS2) | 4 | ILE A 318PHE A 161LEU A 314LEU A 154 | None | 0.89A | 4qopC-1r8gA:undetectable | 4qopC-1r8gA:20.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1si8 | CATALASE (Enterococcusfaecalis) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | ASP A 107PRO A 108PHE A 133LEU A 178 | None | 0.46A | 4qopC-1si8A:57.1 | 4qopC-1si8A:50.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1taq | TAQ DNA POLYMERASE (Thermusaquaticus) |
PF00476(DNA_pol_A)PF01367(5_3_exonuc)PF02739(5_3_exonuc_N)PF09281(Taq-exonuc) | 4 | PRO A 579PHE A 598LEU A 781LEU A 560 | None | 0.93A | 4qopC-1taqA:undetectable | 4qopC-1taqA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgw | 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL SYNTHASE (Neisseriagonorrhoeae) |
PF01128(IspD) | 4 | ILE A 124PRO A 167PHE A 42LEU A 115 | None | 0.84A | 4qopC-1vgwA:undetectable | 4qopC-1vgwA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wpx | CARBOXYPEPTIDASE YINHIBITOR (Saccharomycescerevisiae) |
PF01161(PBP) | 4 | ASP B 587PHE B 634LEU B 619PHE B 638 | None | 0.91A | 4qopC-1wpxB:undetectable | 4qopC-1wpxB:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfu | CALMODULIN-SENSITIVEADENYLATE CYCLASE (Bacillusanthracis) |
PF03497(Anthrax_toxA)PF07737(ATLF) | 4 | ILE A 96PRO A 90PHE A 245LEU A 179 | None | 0.55A | 4qopC-1xfuA:undetectable | 4qopC-1xfuA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y02 | FYVE-RING FINGERPROTEIN SAKURA (Homo sapiens) |
no annotation | 4 | ILE A 93LEU A 88TYR A 87PHE A 71 | None | 0.90A | 4qopC-1y02A:undetectable | 4qopC-1y02A:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2amy | PHOSPHOMANNOMUTASE 2 (Homo sapiens) |
PF03332(PMM) | 4 | ILE A 240PHE A 11TYR A 205LEU A 35 | None | 0.95A | 4qopC-2amyA:undetectable | 4qopC-2amyA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ash | QUEUINETRNA-RIBOSYLTRANSFERASE (Thermotogamaritima) |
PF01702(TGT) | 4 | ILE A 114PHE A 59LEU A 63LEU A 98 | None | 0.79A | 4qopC-2ashA:undetectable | 4qopC-2ashA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c20 | UDP-GLUCOSE4-EPIMERASE (Bacillusanthracis) |
PF01370(Epimerase) | 4 | PHE A 63LEU A 5LEU A 59PHE A 58 | None | 0.93A | 4qopC-2c20A:undetectable | 4qopC-2c20A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hv2 | HYPOTHETICAL PROTEIN (Enterococcusfaecalis) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 4 | PHE A 297LEU A 386LEU A 292PHE A 291 | None | 0.91A | 4qopC-2hv2A:undetectable | 4qopC-2hv2A:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i6x | HYDROLASE, HALOACIDDEHALOGENASE-LIKEFAMILY (Porphyromonasgingivalis) |
PF13419(HAD_2) | 4 | PHE A 46LEU A 80TYR A 113LEU A 63 | None | 0.82A | 4qopC-2i6xA:undetectable | 4qopC-2i6xA:17.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2j2m | CATALASE (Exiguobacteriumoxidotolerans) |
PF00199(Catalase)PF06628(Catalase-rel) | 7 | ILE A 98ASP A 109PRO A 110PHE A 135LEU A 149TYR A 163PHE A 181 | None | 0.25A | 4qopC-2j2mA:60.1 | 4qopC-2j2mA:63.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzs | PUTATIVEALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 4 | ILE A 47TYR A 44LEU A 311PHE A 312 | None | 0.78A | 4qopC-2wzsA:undetectable | 4qopC-2wzsA:21.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xq1 | PEROXISOMAL CATALASE (Ogataea angusta) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | ASP A 118PRO A 119PHE A 144LEU A 189PHE A 190 | None | 0.46A | 4qopC-2xq1A:53.1 | 4qopC-2xq1A:44.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xty | QNRB1 (Klebsiellapneumoniae) |
PF00805(Pentapeptide)PF13599(Pentapeptide_4) | 4 | PHE A 76LEU A 61LEU A 71PHE A 45 | None | 0.88A | 4qopC-2xtyA:undetectable | 4qopC-2xtyA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn0 | TRANSCRIPTION FACTORTAU 55 KDA SUBUNIT (Saccharomycescerevisiae) |
PF00300(His_Phos_1) | 4 | ILE A 8PHE A 146LEU A 176PHE A 231 | None | 0.94A | 4qopC-2yn0A:undetectable | 4qopC-2yn0A:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yn2 | UNCHARACTERIZEDPROTEIN YNL108C (Saccharomycescerevisiae) |
PF00300(His_Phos_1) | 4 | ILE A 8PHE A 145LEU A 175PHE A 218 | None | 0.91A | 4qopC-2yn2A:undetectable | 4qopC-2yn2A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z36 | CYTOCHROME P450 TYPECOMPACTIN3'',4''-HYDROXYLASE (Nonomuraearecticatena) |
PF00067(p450) | 4 | PHE A 174LEU A 197LEU A 164PHE A 217 | None | 0.87A | 4qopC-2z36A:undetectable | 4qopC-2z36A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiz | DNA POLYMERASESLIDING CLAMP C (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 4 | ILE C 154PHE C 139LEU C 165LEU C 227 | None | 0.84A | 4qopC-3aizC:undetectable | 4qopC-3aizC:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3axi | OLIGO-1,6-GLUCOSIDASE IMA1 (Saccharomycescerevisiae) |
PF00128(Alpha-amylase) | 4 | PHE A 528LEU A 382LEU A 541PHE A 543 | None | 0.77A | 4qopC-3axiA:undetectable | 4qopC-3axiA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bg2 | DGTPTRIPHOSPHOHYDROLASE (Leeuwenhoekiellablandensis) |
PF01966(HD) | 4 | ILE A 22TYR A 100LEU A 29PHE A 31 | None | 0.87A | 4qopC-3bg2A:undetectable | 4qopC-3bg2A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cax | UNCHARACTERIZEDPROTEIN PF0695 (Pyrococcusfuriosus) |
PF01814(Hemerythrin)PF13596(PAS_10) | 4 | ILE A 161PHE A 232LEU A 149LEU A 221 | None | 0.86A | 4qopC-3caxA:undetectable | 4qopC-3caxA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dv9 | BETA-PHOSPHOGLUCOMUTASE (Bacteroidesvulgatus) |
PF13419(HAD_2) | 4 | PHE A 201LEU A 241LEU A 222PHE A 224 | None | 0.69A | 4qopC-3dv9A:undetectable | 4qopC-3dv9A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jqy | POLYSIALIC ACIDO-ACETYLTRANSFERASE (Escherichiacoli) |
no annotation | 4 | ILE B 94LEU B 75LEU B 64PHE B 42 | None | 0.88A | 4qopC-3jqyB:undetectable | 4qopC-3jqyB:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k5p | D-3-PHOSPHOGLYCERATEDEHYDROGENASE (Brucellaabortus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | ILE A 20PHE A 28LEU A 16LEU A 313 | None | 0.93A | 4qopC-3k5pA:undetectable | 4qopC-3k5pA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3e | UNCHARACTERIZEDPROTEIN YQJG (Escherichiacoli) |
PF13409(GST_N_2)PF13410(GST_C_2) | 4 | ILE A 264ASP A 250PRO A 251LEU A 274 | None | 0.88A | 4qopC-3r3eA:undetectable | 4qopC-3r3eA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rc3 | ATP-DEPENDENT RNAHELICASE SUPV3L1,MITOCHONDRIAL (Homo sapiens) |
PF00271(Helicase_C)PF12513(SUV3_C) | 4 | ILE A 655PHE A 593LEU A 608PHE A 585 | None | 0.95A | 4qopC-3rc3A:undetectable | 4qopC-3rc3A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tj7 | GBAA_1210 PROTEIN (Bacillusanthracis) |
PF01928(CYTH) | 4 | ILE A 171LEU A 166LEU A 133PHE A 128 | None | 0.94A | 4qopC-3tj7A:undetectable | 4qopC-3tj7A:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v7o | MINOR NUCLEOPROTEINVP30 (Restonebolavirus) |
PF11507(Transcript_VP30) | 4 | ILE A 108PHE A 101LEU A 48LEU A 36 | None | 0.94A | 4qopC-3v7oA:undetectable | 4qopC-3v7oA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 4 | ILE A 934PRO A 905TYR A 876PHE A 556 | None | 0.81A | 4qopC-3w9iA:undetectable | 4qopC-3w9iA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 4 | PHE A 925LEU A 393LEU A 564PHE A 563 | None | 0.70A | 4qopC-3w9iA:undetectable | 4qopC-3w9iA:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zhp | CALCIUM-BINDINGPROTEIN 39-LIKE (Homo sapiens) |
PF08569(Mo25) | 4 | ILE A 290PHE A 277LEU A 255LEU A 301 | None | 0.93A | 4qopC-3zhpA:undetectable | 4qopC-3zhpA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zzi | ACETYLGLUTAMATEKINASE (Saccharomycescerevisiae) |
PF00696(AA_kinase)PF04768(NAT) | 4 | PHE A 99TYR A 87LEU A 123PHE A 122 | None | 0.88A | 4qopC-3zziA:undetectable | 4qopC-3zziA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a22 | FRUCTOSE-BISPHOSPHATE ALDOLASE (Mycobacteriumtuberculosis) |
PF01116(F_bP_aldolase) | 4 | ILE A 137LEU A 141LEU A 204PHE A 247 | None | 0.91A | 4qopC-4a22A:undetectable | 4qopC-4a22A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4age | SMALL-CONDUCTANCEMECHANOSENSITIVECHANNEL (Escherichiacoli) |
PF00924(MS_channel)PF05552(TM_helix) | 4 | ILE A 165PHE A 130LEU A 138LEU A 124 | None | 0.70A | 4qopC-4ageA:undetectable | 4qopC-4ageA:20.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4cab | CATALASE (Deinococcusradiodurans) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | ASP A 139PRO A 140PHE A 165LEU A 210 | None | 0.25A | 4qopC-4cabA:55.1 | 4qopC-4cabA:51.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d9o | MEMBRANE-ASSOCIATEDPROTEIN VP24 (Restonebolavirus) |
PF06389(Filo_VP24) | 4 | ILE A 188PHE A 160LEU A 164PHE A 227 | None | 0.90A | 4qopC-4d9oA:undetectable | 4qopC-4d9oA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4flx | DNA POLYMERASE 1 (Pyrococcusabyssi) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | ILE A 567PHE A 406LEU A 577LEU A 544 | ILE A 567 ( 0.4A)PHE A 406 ( 1.3A)LEU A 577 ( 0.5A)LEU A 544 ( 0.6A) | 0.90A | 4qopC-4flxA:undetectable | 4qopC-4flxA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g2r | ACCD6,CARBOXYLTRANSFERASEBETA-SUBUNIT OFACYL-COA CARBOXYLASE (Mycobacteriumtuberculosis) |
PF01039(Carboxyl_trans) | 4 | ILE A 128PHE A 261LEU A 208LEU A 309 | None | 0.90A | 4qopC-4g2rA:undetectable | 4qopC-4g2rA:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4geq | KINETOCHORE PROTEINSPC25 (Saccharomycescerevisiae) |
no annotation | 4 | ILE A 181LEU A 196LEU A 217PHE A 163 | None | 0.72A | 4qopC-4geqA:undetectable | 4qopC-4geqA:11.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl9 | TYROSINE-PROTEINKINASE (Mus musculus) |
PF07714(Pkinase_Tyr) | 5 | ILE A1126PHE A1048LEU A 954LEU A1044PHE A1040 | None | 1.35A | 4qopC-4gl9A:undetectable | 4qopC-4gl9A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6v | AMIDOHYDROLASE 2 (Planctopiruslimnophila) |
PF02614(UxaC) | 4 | ILE A 215LEU A 217LEU A 305PHE A 306 | None | 0.78A | 4qopC-4i6vA:undetectable | 4qopC-4i6vA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5n | EARLY PROTEIN GP1BURACIL-DNAGLYCOSYLASE (Bacillus virusphi29;Humanalphaherpesvirus1) |
PF03167(UDG)no annotation | 4 | ILE C 47PHE C 36LEU C 50LEU A 214 | None | 0.88A | 4qopC-4l5nC:undetectable | 4qopC-4l5nC:8.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 4 | PHE A 172LEU A 195TYR A 188PHE A 300 | None | 0.94A | 4qopC-4nkyA:undetectable | 4qopC-4nkyA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o7z | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (Pyrococcushorikoshii) |
PF01259(SAICAR_synt) | 4 | ILE A 169LEU A 164TYR A 163LEU A 52 | None | 0.94A | 4qopC-4o7zA:undetectable | 4qopC-4o7zA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppz | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Neisseriameningitidis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | ILE A 276PHE A 256LEU A 216LEU A 187 | None | 0.94A | 4qopC-4ppzA:undetectable | 4qopC-4ppzA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv5 | LACTOYLGLUTATHIONELYASE (Mus musculus) |
PF00903(Glyoxalase) | 4 | ILE A 39ASP A 168PRO A 167LEU A 101 | None | 0.87A | 4qopC-4pv5A:undetectable | 4qopC-4pv5A:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbj | GLYCYLPEPTIDEN-TETRADECANOYLTRANSFERASE (Aspergillusfumigatus) |
PF01233(NMT)PF02799(NMT_C) | 4 | PHE A 370TYR A 395LEU A 320PHE A 333 | None | 0.90A | 4qopC-4qbjA:undetectable | 4qopC-4qbjA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qn8 | VIPE (Legionellapneumophila) |
no annotation | 5 | ILE A 22PHE A 105LEU A 17LEU A 101PHE A 36 | None | 1.31A | 4qopC-4qn8A:undetectable | 4qopC-4qn8A:16.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qor | CATALASE (Bacilluspumilus) |
PF00199(Catalase)PF06628(Catalase-rel) | 8 | ILE A 99ASP A 110PRO A 111PHE A 136LEU A 150TYR A 164LEU A 181PHE A 182 | None2CH A 503 (-4.1A)None2CH A 503 (-4.1A)2CH A 503 (-4.2A)2CH A 503 (-4.1A)2CH A 503 (-4.8A)2CH A 503 ( 4.8A) | 0.12A | 4qopC-4qorA:64.4 | 4qopC-4qorA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r5o | QUINONPROTEINALCOHOLDEHYDROGENASE-LIKEPROTEIN (Bacteroidesthetaiotaomicron) |
PF16819(DUF5074)PF16820(PKD_3) | 4 | ILE A 168PHE A 188LEU A 211LEU A 231 | None | 0.93A | 4qopC-4r5oA:undetectable | 4qopC-4r5oA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvs | TORSIN-1A-INTERACTING PROTEIN 1 (Homo sapiens) |
PF05609(LAP1C) | 4 | PHE A 492LEU A 510LEU A 465PHE A 469 | None | 0.86A | 4qopC-4tvsA:undetectable | 4qopC-4tvsA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u1d | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT A (Saccharomycescerevisiae) |
no annotation | 4 | PRO C 457PHE C 417LEU C 424LEU C 408 | None | 0.65A | 4qopC-4u1dC:undetectable | 4qopC-4u1dC:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uer | EIF3A (Lachanceakluyveri) |
no annotation | 4 | PRO a 457PHE a 417LEU a 424LEU a 408 | None | 0.66A | 4qopC-4uera:undetectable | 4qopC-4uera:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v2d | FIBRONECTIN LEUCINERICH TRANSMEMBRANEPROTEIN 2 (Homo sapiens) |
PF01463(LRRCT)PF13855(LRR_8) | 4 | ILE A 192PHE A 200LEU A 209PHE A 235 | None | 0.93A | 4qopC-4v2dA:undetectable | 4qopC-4v2dA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbo | RHODOPSIN KINASE (Bos taurus) |
PF00069(Pkinase)PF00615(RGS) | 4 | ILE A 298PHE A 423LEU A 375TYR A 372 | None | 0.92A | 4qopC-4wboA:undetectable | 4qopC-4wboA:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wkw | UNCHARACTERIZEDPROTEIN (Mycobacteriumleprae) |
PF01323(DSBA) | 4 | ILE A 24PRO A 154LEU A 13PHE A 42 | None | 0.80A | 4qopC-4wkwA:undetectable | 4qopC-4wkwA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wlp | NUCLEAR FACTORRELATED TOKAPPA-B-BINDINGPROTEINUBIQUITINCARBOXYL-TERMINALHYDROLASE ISOZYME L5 (Homo sapiens) |
PF01088(Peptidase_C12)no annotation | 4 | PHE A 43LEU A 52LEU A 38PHE B 100 | None | 0.84A | 4qopC-4wlpA:undetectable | 4qopC-4wlpA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wvm | STONUSTOXIN SUBUNITALPHA (Synanceiahorrida) |
PF00622(SPRY)PF13765(PRY) | 4 | ILE A 311LEU A 419TYR A 418LEU A 361 | None | 0.83A | 4qopC-4wvmA:undetectable | 4qopC-4wvmA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xix | CARBONIC ANHYDRASE,ALPHA TYPE (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 4 | ILE A 195LEU A 235LEU A 156PHE A 141 | None | 0.94A | 4qopC-4xixA:undetectable | 4qopC-4xixA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxc | HYDROQUINONEDIOXYGENASE LARGESUBUNIT (Pseudomonas sp.WBC-3) |
no annotation | 4 | ILE W 48PHE W 129LEU W 39PHE W 120 | None | 0.76A | 4qopC-4zxcW:undetectable | 4qopC-4zxcW:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5t | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT K (Oryctolaguscuniculus) |
PF10075(CSN8_PSD8_EIF3K) | 4 | ILE K 131LEU K 71LEU K 121PHE K 117 | None | 0.86A | 4qopC-5a5tK:undetectable | 4qopC-5a5tK:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwu | NUCLEOPORIN NUP188 (Chaetomiumthermophilum) |
no annotation | 4 | ILE A1574LEU A1515LEU A1631PHE A1627 | GOL A1901 (-4.6A)NoneNoneNone | 0.73A | 4qopC-5cwuA:undetectable | 4qopC-5cwuA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e6s | INTEGRIN ALPHA-LINTEGRIN BETA-2 (Homo sapiens) |
PF00092(VWA)PF00362(Integrin_beta)PF01839(FG-GAP)PF08441(Integrin_alpha2)PF17205(PSI_integrin) | 4 | ILE A 431LEU B 311TYR B 308LEU B 215 | None | 0.93A | 4qopC-5e6sA:undetectable | 4qopC-5e6sA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h83 | HETEROYOHIMBINESYNTHASE HYS (Catharanthusroseus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ILE A 327PRO A 28LEU A 354PHE A 31 | None | 0.83A | 4qopC-5h83A:undetectable | 4qopC-5h83A:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j9g | GLYCERALDEHYDE-3-PDEHYDROGENASE (Lactobacillusacidophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ILE A 21PHE A 10TYR A 76LEU A 49 | None | 0.86A | 4qopC-5j9gA:undetectable | 4qopC-5j9gA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jqk | PEPTIDASE, PUTATIVE (Plasmodiumfalciparum) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 4 | ILE A 448PHE A 456LEU A 444LEU A 419 | None | 0.95A | 4qopC-5jqkA:undetectable | 4qopC-5jqkA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k8s | CAMP-DEPENDENTPROTEIN KINASEREGULATORY SUBUNIT (Plasmodiumfalciparum) |
PF00027(cNMP_binding) | 4 | ILE A 413PHE A 406TYR A 374LEU A 381 | None | 0.61A | 4qopC-5k8sA:undetectable | 4qopC-5k8sA:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kbf | CAMP-DEPENDENTPROTEIN KINASEREGULATORY SUBUNIT,PUTATIVE (Plasmodiumfalciparum) |
PF00027(cNMP_binding) | 4 | ILE A 413PHE A 406TYR A 374LEU A 381 | None | 0.58A | 4qopC-5kbfA:undetectable | 4qopC-5kbfA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5me3 | SISTER CHROMATIDCOHESION PROTEIN 2 (Eremotheciumgossypii) |
PF12765(Cohesin_HEAT)PF12830(Nipped-B_C) | 4 | PHE A1315LEU A1272LEU A1298PHE A1297 | None | 0.95A | 4qopC-5me3A:undetectable | 4qopC-5me3A:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ng6 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Francisellatularensis) |
no annotation | 4 | PHE A 489LEU A 536LEU A 374PHE A 378 | None | 0.87A | 4qopC-5ng6A:undetectable | 4qopC-5ng6A:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nvm | EUKARYOTICTRANSLATIONINITIATION FACTOR 4ETYPE 2 (Homo sapiens) |
PF01652(IF4E) | 4 | ILE A 152PHE A 88LEU A 115LEU A 56 | None | 0.90A | 4qopC-5nvmA:undetectable | 4qopC-5nvmA:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sui | RIBOSOME BIOGENESISPROTEIN NSA1 (Saccharomycescerevisiae) |
no annotation | 5 | ILE A 209PHE A 275LEU A 221LEU A 256PHE A 194 | None | 1.48A | 4qopC-5suiA:undetectable | 4qopC-5suiA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tcs | KINETOCHORE PROTEINSPC25 (Saccharomycescerevisiae) |
no annotation | 4 | ILE D 181LEU D 196LEU D 217PHE D 163 | None | 0.74A | 4qopC-5tcsD:undetectable | 4qopC-5tcsD:12.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5td8 | KINETOCHORE PROTEINSPC25 (Saccharomycescerevisiae) |
no annotation | 4 | ILE D 181LEU D 196LEU D 217PHE D 163 | NoneNone HG D 301 (-3.0A) HG D 301 (-3.6A) | 0.80A | 4qopC-5td8D:undetectable | 4qopC-5td8D:12.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v9x | ATP-DEPENDENT DNAHELICASE (Mycolicibacteriumsmegmatis) |
no annotation | 4 | ILE A 706LEU A 721LEU A 733PHE A 734 | None | 0.80A | 4qopC-5v9xA:undetectable | 4qopC-5v9xA:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y4j | XYLOSE ISOMERASE (Streptomycesrubiginosus) |
PF01261(AP_endonuc_2) | 4 | ILE A 120PHE A 104LEU A 93PHE A 99 | None | 0.85A | 4qopC-5y4jA:undetectable | 4qopC-5y4jA:24.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yhu | MYELIN REGULATORYFACTOR (Homo sapiens) |
no annotation | 4 | PRO A 405PHE A 420LEU A 510LEU A 417 | None | 0.89A | 4qopC-5yhuA:undetectable | 4qopC-5yhuA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxa | NON-STRUCTURALPROTEIN 1 (Yellow fevervirus) |
no annotation | 4 | ILE A 42PRO A 79PHE A 29LEU A 45 | None | 0.90A | 4qopC-5yxaA:undetectable | 4qopC-5yxaA:9.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z43 | AMBP1 (Fischerellaambigua) |
no annotation | 4 | PHE A 158LEU A 136LEU A 155PHE A 171 | None | 0.84A | 4qopC-5z43A:undetectable | 4qopC-5z43A:12.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zh6 | - (-) |
no annotation | 4 | PHE A 68LEU A 48LEU A 33PHE A 28 | None | 0.82A | 4qopC-5zh6A:undetectable | 4qopC-5zh6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zhu | MYELIN REGULATORYFACTOR (Homo sapiens) |
no annotation | 4 | PRO A 405PHE A 420LEU A 510LEU A 417 | None | 0.88A | 4qopC-5zhuA:undetectable | 4qopC-5zhuA:9.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ao8 | ARGININE--TRNALIGASE (Neisseriagonorrhoeae) |
PF00750(tRNA-synt_1d)PF03485(Arg_tRNA_synt_N)PF05746(DALR_1) | 4 | PHE A 301TYR A 312LEU A 347PHE A 344 | NoneARG A 601 (-4.4A)NoneARG A 601 (-4.8A) | 0.92A | 4qopC-6ao8A:undetectable | 4qopC-6ao8A:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fhs | RUVB-LIKE HELICASE (Chaetomiumthermophilum) |
no annotation | 4 | ILE A 302PHE A 355LEU A 330LEU A 320 | None | 0.94A | 4qopC-6fhsA:undetectable | 4qopC-6fhsA:10.86 |