SIMILAR PATTERNS OF AMINO ACIDS FOR 4QD3_A_5AEA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aqc X11

(Homo sapiens) 		PF00640
(PID) 		5 GLY A 423
ASN A 424
VAL A 361
VAL A 462
LEU A 337
 None
 1.11A 4qd3A-1aqcA:
undetectable		 4qd3A-1aqcA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cmv HUMAN
CYTOMEGALOVIRUS
PROTEASE

(Human
betaherpesvirus
5) 		PF00716
(Peptidase_S21) 		5 LEU A 187
GLY A 194
VAL A  78
SER A  77
LEU A  82
 None
 1.11A 4qd3A-1cmvA:
undetectable		 4qd3A-1cmvA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ek6 UDP-GALACTOSE
4-EPIMERASE

(Homo sapiens) 		PF16363
(GDP_Man_Dehyd) 		5 LEU A  49
GLY A  12
VAL A  31
VAL A  19
LEU A  22
 None
NAI  A 400 (-3.3A)
None
None
None
 1.15A 4qd3A-1ek6A:
2.7		 4qd3A-1ek6A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1glo CATHEPSIN S

(Homo sapiens) 		PF00112
(Peptidase_C1) 		5 LEU A 124
GLY A 170
VAL A 134
SER A 135
VAL A 136
 None
 1.15A 4qd3A-1gloA:
undetectable		 4qd3A-1gloA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF13407
(Peripla_BP_4) 		5 LEU A 257
GLY A  62
VAL A  34
SER A  33
VAL A  32
 None
 1.03A 4qd3A-1gudA:
3.5		 4qd3A-1gudA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7o 4-HYDROXYPHENYLACETA
TE DEGRADATION
BIFUNCTIONAL
ISOMERASE/DECARBOXYL
ASE

(Escherichia
coli) 		PF01557
(FAA_hydrolase) 		5 GLY A 114
VAL A  95
SER A  96
VAL A  60
LEU A  97
 None
 1.22A 4qd3A-1i7oA:
undetectable		 4qd3A-1i7oA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvg DNA TOPOISOMERASE II

(Saccharomyces
cerevisiae) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		5 LEU A 242
GLY A 239
ASN A  87
VAL A 223
LEU A  68
 None
 1.10A 4qd3A-1pvgA:
undetectable		 4qd3A-1pvgA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sqj OLIGOXYLOGLUCAN
REDUCING-END-SPECIFI
C CELLOBIOHYDROLASE

(Geotrichum sp.
M128) 		PF15899
(BNR_6) 		5 LEU A 657
HIS A 659
VAL A 678
SER A 679
VAL A 698
 None
 1.04A 4qd3A-1sqjA:
undetectable		 4qd3A-1sqjA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrd INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Thermotoga
maritima) 		PF00478
(IMPDH)
PF00571
(CBS) 		5 LEU A  40
GLY A  61
ASN A 205
VAL A 425
VAL A 429
 None
 1.16A 4qd3A-1vrdA:
undetectable		 4qd3A-1vrdA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wkr POLYPOROPEPSIN

(Irpex lacteus) 		PF00026
(Asp) 		5 LEU A 160
GLY A 158
VAL A  16
VAL A  31
LEU A  30
 None
 1.09A 4qd3A-1wkrA:
undetectable		 4qd3A-1wkrA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zfj INOSINE
MONOPHOSPHATE
DEHYDROGENASE

(Streptococcus
pyogenes) 		PF00478
(IMPDH)
PF00571
(CBS) 		5 LEU A 441
GLY A  69
HIS A 214
VAL A 437
SER A 434
 None
 1.05A 4qd3A-1zfjA:
undetectable		 4qd3A-1zfjA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrr E-2/E-2' PROTEIN

(Klebsiella
oxytoca) 		PF03079
(ARD) 		5 LEU A 115
GLY A  32
VAL A 134
SER A 133
LEU A 131
 None
 1.20A 4qd3A-1zrrA:
undetectable		 4qd3A-1zrrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0y PROCATHEPSIN S

(Homo sapiens) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		5 LEU A 223
GLY A 269
VAL A 233
SER A 234
VAL A 235
 None
 1.15A 4qd3A-2c0yA:
undetectable		 4qd3A-2c0yA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ci6 NG,
NG-DIMETHYLARGININE
DIMETHYLAMINOHYDROLA
SE 1

(Bos taurus) 		PF02274
(Amidinotransf) 		5 GLY A  51
VAL A  17
SER A 275
VAL A  15
LEU A 277
 None
 0.83A 4qd3A-2ci6A:
undetectable		 4qd3A-2ci6A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dph FORMALDEHYDE
DISMUTASE

(Pseudomonas
putida) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 LEU A 148
GLY A  70
VAL A 141
VAL A  35
LEU A  24
 None
 1.22A 4qd3A-2dphA:
undetectable		 4qd3A-2dphA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fo5 CYSTEINE PROTEINASE
EP-B 2

(Hordeum vulgare) 		PF00112
(Peptidase_C1) 		5 LEU A 129
GLY A 173
VAL A 138
SER A 139
VAL A 140
 None
 1.19A 4qd3A-2fo5A:
undetectable		 4qd3A-2fo5A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		5 LEU A 250
GLY A 184
VAL A 306
SER A 307
LEU A 311
 None
 0.90A 4qd3A-2o2zA:
undetectable		 4qd3A-2o2zA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o96 26S PROTEASOME
NON-ATPASE
REGULATORY SUBUNIT 7

(Homo sapiens) 		PF01398
(JAB) 		5 GLY A  37
VAL A  19
SER A  18
VAL A  15
LEU A  14
 None
 1.04A 4qd3A-2o96A:
undetectable		 4qd3A-2o96A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odf HYPOTHETICAL PROTEIN
ATU2144

(Agrobacterium
fabrum) 		PF05013
(FGase) 		5 LEU A 179
GLY A 249
VAL A 149
VAL A 151
LEU A  29
 None
 0.94A 4qd3A-2odfA:
3.8		 4qd3A-2odfA:
24.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pth PEPTIDYL-TRNA
HYDROLASE

(Escherichia
coli) 		PF01195
(Pept_tRNA_hydro) 		8 HIS A  20
LEU A  95
GLY A 112
HIS A 113
ASN A 114
VAL A 145
VAL A 149
LEU A 150
 None
 0.43A 4qd3A-2pthA:
33.7		 4qd3A-2pthA:
59.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vk9 ALPHA-TOXIN

(Clostridium
novyi) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		5 GLY A 458
VAL A 433
SER A 434
VAL A 437
LEU A 438
 None
 0.71A 4qd3A-2vk9A:
undetectable		 4qd3A-2vk9A:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr5 GLYCOGEN OPERON
PROTEIN GLGX

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		5 LEU A 333
ASN A 379
VAL A 340
VAL A 344
LEU A 345
 None
 1.18A 4qd3A-2vr5A:
undetectable		 4qd3A-2vr5A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vt1 SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAS

(Shigella
flexneri) 		PF01312
(Bac_export_2) 		5 LEU B 310
GLY B 264
VAL B 320
VAL B 328
LEU B 329
 None
 1.16A 4qd3A-2vt1B:
undetectable		 4qd3A-2vt1B:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3c GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Homo sapiens) 		PF04869
(Uso1_p115_head) 		5 LEU A 316
GLY A 311
VAL A 340
VAL A 287
LEU A 290
 None
 1.11A 4qd3A-2w3cA:
undetectable		 4qd3A-2w3cA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnk SPOROZOITE-SPECIFIC
SAG PROTEIN

(Toxoplasma
gondii) 		PF04092
(SAG) 		5 LEU A  63
VAL A  96
SER A  95
VAL A 127
LEU A 126
 None
 1.22A 4qd3A-2wnkA:
undetectable		 4qd3A-2wnkA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwu IMPORTIN13

(Homo sapiens) 		PF03810
(IBN_N)
PF08389
(Xpo1) 		5 HIS B 582
VAL B 572
SER B 573
VAL B 576
LEU B 577
 None
 0.93A 4qd3A-2xwuB:
undetectable		 4qd3A-2xwuB:
10.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2z2i PEPTIDYL-TRNA
HYDROLASE

(Mycobacterium
tuberculosis) 		PF01195
(Pept_tRNA_hydro) 		6 HIS A  22
LEU A  97
GLY A 114
HIS A 115
VAL A 150
LEU A 151
 None
 0.52A 4qd3A-2z2iA:
26.8		 4qd3A-2z2iA:
37.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3t CYTOCHROME P450

(Streptomyces
sp. TP-A0274) 		PF00067
(p450) 		5 LEU A 369
GLY A 255
VAL A 160
SER A 162
LEU A 165
 None
HEM  A 500 (-3.6A)
None
None
None
 1.19A 4qd3A-2z3tA:
undetectable		 4qd3A-2z3tA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a18 ALDOXIME DEHYDRATASE

(Rhodococcus
erythropolis) 		PF13816
(Dehydratase_hem) 		5 LEU A 193
GLY A 342
HIS A 282
VAL A 208
LEU A 331
 None
 1.13A 4qd3A-3a18A:
undetectable		 4qd3A-3a18A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)

(Thermus
thermophilus) 		PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb) 		6 LEU A 422
GLY A 420
HIS A 417
VAL A 437
SER A 438
VAL A 414
 None
None
None
None
ZN  A 579 ( 4.4A)
None
 1.44A 4qd3A-3auoA:
undetectable		 4qd3A-3auoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxp GLUCOSAMINE
6-PHOSPHATE
N-ACETYLTRANSFERASE

(Homo sapiens) 		PF00583
(Acetyltransf_1) 		5 LEU A 133
GLY A 130
VAL A 124
SER A 125
VAL A  98
 None
 1.13A 4qd3A-3cxpA:
undetectable		 4qd3A-3cxpA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6j PUTATIVE HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bacteroides
fragilis) 		PF13419
(HAD_2) 		5 LEU A 148
GLY A 173
VAL A 180
SER A 181
LEU A 163
 None
 1.13A 4qd3A-3d6jA:
3.9		 4qd3A-3d6jA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dm0 MALTOSE-BINDING
PERIPLASMIC PROTEIN
FUSED WITH RACK1

(Arabidopsis
thaliana;
Escherichia
coli) 		PF00400
(WD40)
PF01547
(SBP_bac_1) 		5 GLY A1085
HIS A1104
SER A1080
VAL A1111
LEU A1079
 None
 1.13A 4qd3A-3dm0A:
undetectable		 4qd3A-3dm0A:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0f PUTATIVE
METAL-DEPENDENT
PHOSPHOESTERASE

(Bifidobacterium
adolescentis) 		PF02811
(PHP) 		5 LEU A 213
GLY A 204
VAL A  84
SER A  83
VAL A  82
 None
 1.11A 4qd3A-3e0fA:
undetectable		 4qd3A-3e0fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e2v 3'-5'-EXONUCLEASE

(Saccharomyces
cerevisiae) 		PF01026
(TatD_DNase) 		5 LEU A 322
GLY A 299
ASN A 301
VAL A 314
VAL A 393
 None
 1.19A 4qd3A-3e2vA:
undetectable		 4qd3A-3e2vA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ffs INOSINE-5-MONOPHOSPH
ATE DEHYDROGENASE

(Cryptosporidium
parvum) 		PF00478
(IMPDH) 		5 LEU A  45
GLY A  66
ASN A 126
VAL A 345
VAL A 349
 None
 1.19A 4qd3A-3ffsA:
undetectable		 4qd3A-3ffsA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fmc PUTATIVE
SUCCINYLGLUTAMATE
DESUCCINYLASE /
ASPARTOACYLASE

(Shewanella
amazonensis) 		PF04952
(AstE_AspA) 		5 LEU A 357
HIS A 345
VAL A 351
SER A 350
VAL A 300
 None
 0.99A 4qd3A-3fmcA:
2.7		 4qd3A-3fmcA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gq2 GENERAL VESICULAR
TRANSPORT FACTOR
P115

(Bos taurus) 		PF04869
(Uso1_p115_head) 		5 LEU A 316
GLY A 311
VAL A 340
VAL A 287
LEU A 290
 None
 1.09A 4qd3A-3gq2A:
undetectable		 4qd3A-3gq2A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hka URONATE ISOMERASE

(Bacillus
halodurans) 		no annotation 5 LEU A 185
ASN A 235
VAL A 192
SER A 200
VAL A 204
 None
 1.18A 4qd3A-3hkaA:
undetectable		 4qd3A-3hkaA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwk METHYLCITRATE
SYNTHASE

(Mycobacterium
tuberculosis) 		PF00285
(Citrate_synt) 		5 HIS A 281
GLY A 208
HIS A 207
ASN A 210
VAL A 283
 SIN  A 401 ( 4.1A)
SIN  A 402 (-3.5A)
SIN  A 402 ( 3.6A)
SIN  A 401 (-3.3A)
None
 1.16A 4qd3A-3hwkA:
undetectable		 4qd3A-3hwkA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ica PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN

(Porphyromonas
gingivalis) 		no annotation 5 LEU A  14
GLY A 113
VAL A 140
VAL A 144
LEU A 145
 None
 0.89A 4qd3A-3icaA:
undetectable		 4qd3A-3icaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3in5 DNA POLYMERASE KAPPA

(Homo sapiens) 		PF00817
(IMS)
PF11798
(IMS_HHH)
PF11799
(IMS_C) 		5 LEU A 349
GLY A 401
ASN A 316
VAL A 354
VAL A 322
 None
 0.99A 4qd3A-3in5A:
undetectable		 4qd3A-3in5A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3le2 SERPIN-ZX

(Arabidopsis
thaliana) 		PF00079
(Serpin) 		5 LEU A 261
ASN A 375
VAL A 371
VAL A 380
LEU A 381
 None
ACT  A 393 ( 4.9A)
None
None
None
 1.09A 4qd3A-3le2A:
undetectable		 4qd3A-3le2A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lyu PUTATIVE HYDROGENASE

(Pyrococcus
furiosus) 		no annotation 5 LEU A 176
GLY A 106
VAL A 204
VAL A 180
LEU A 184
 None
 1.11A 4qd3A-3lyuA:
2.1		 4qd3A-3lyuA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcw PUTATIVE HYDROLASE

(Chromobacterium
violaceum) 		PF00857
(Isochorismatase) 		5 HIS A 166
LEU A 142
GLY A 146
VAL A 126
SER A 121
 None
None
None
None
EDO  A 204 (-3.6A)
 1.05A 4qd3A-3mcwA:
undetectable		 4qd3A-3mcwA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mn3 CARBON
CATABOLITE-DEREPRESS
ING PROTEIN KINASE

(Saccharomyces
cerevisiae) 		PF00069
(Pkinase) 		5 LEU A  83
GLY A  53
ASN A  54
VAL A 131
VAL A  81
 None
 1.08A 4qd3A-3mn3A:
undetectable		 4qd3A-3mn3A:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3nea PEPTIDYL-TRNA
HYDROLASE

(Francisella
tularensis) 		PF01195
(Pept_tRNA_hydro) 		8 HIS A  22
LEU A  97
GLY A 114
HIS A 115
ASN A 116
VAL A 146
VAL A 150
LEU A 151
 EDO  A 511 (-4.6A)
None
None
EDO  A 511 ( 4.5A)
EDO  A 511 ( 4.9A)
None
None
None
 0.40A 4qd3A-3neaA:
33.1		 4qd3A-3neaA:
44.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ovz CATHEPSIN K

(Homo sapiens) 		PF00112
(Peptidase_C1) 		5 LEU A 121
GLY A 168
VAL A 131
SER A 132
VAL A 133
 None
 1.22A 4qd3A-3ovzA:
undetectable		 4qd3A-3ovzA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s1v PROBABLE
TRANSALDOLASE

(Thermoplasma
acidophilum) 		PF00923
(TAL_FSA) 		5 GLY A  80
HIS A  77
VAL A  59
SER A  58
VAL A  85
 None
 1.20A 4qd3A-3s1vA:
undetectable		 4qd3A-3s1vA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5n 4-HYDROXY-2-OXOGLUTA
RATE ALDOLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00701
(DHDPS) 		5 LEU A  57
GLY A  79
VAL A  92
VAL A  96
LEU A 106
 EDO  A   3 ( 4.9A)
None
None
None
None
 1.19A 4qd3A-3s5nA:
undetectable		 4qd3A-3s5nA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfv LIDA PROTEIN,
SUBSTRATE OF THE
DOT/ICM SYSTEM

(Legionella
pneumophila) 		no annotation 5 LEU B 247
GLY B 433
ASN B 435
VAL B 542
VAL B 538
 None
 0.98A 4qd3A-3sfvB:
undetectable		 4qd3A-3sfvB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tnf LIDA

(Legionella
pneumophila) 		no annotation 5 LEU B 247
GLY B 433
ASN B 435
VAL B 542
VAL B 538
 None
 0.98A 4qd3A-3tnfB:
undetectable		 4qd3A-3tnfB:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsd INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Bacillus
anthracis) 		PF00478
(IMPDH)
PF00571
(CBS) 		5 LEU A  46
GLY A  67
ASN A 212
VAL A 432
VAL A 436
 None
 1.13A 4qd3A-3tsdA:
undetectable		 4qd3A-3tsdA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ugm TAL EFFECTOR
AVRBS3/PTHA

(Xanthomonas
oryzae) 		PF03377
(TAL_effector) 		5 GLY A 525
HIS A 524
VAL A 566
VAL A 547
LEU A 544
 None
 1.10A 4qd3A-3ugmA:
undetectable		 4qd3A-3ugmA:
12.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v2i PEPTIDYL-TRNA
HYDROLASE

(Burkholderia
thailandensis) 		PF01195
(Pept_tRNA_hydro) 		8 HIS A  20
LEU A  95
GLY A 112
HIS A 113
ASN A 114
VAL A 154
VAL A 158
LEU A 159
 None
 0.53A 4qd3A-3v2iA:
33.4		 4qd3A-3v2iA:
47.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vov GLUCOKINASE

(Thermus
thermophilus) 		PF00480
(ROK) 		5 LEU A   8
GLY A  10
ASN A  81
VAL A  39
VAL A  85
 None
 1.08A 4qd3A-3vovA:
undetectable		 4qd3A-3vovA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zqj UVRABC SYSTEM
PROTEIN A

(Mycobacterium
tuberculosis) 		PF00005
(ABC_tran) 		5 LEU A 663
GLY A 631
HIS A 686
VAL A 642
SER A 643
 None
 1.19A 4qd3A-3zqjA:
undetectable		 4qd3A-3zqjA:
12.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E

(Streptomyces
cinnabarigriseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		5 LEU A 184
GLY A 119
VAL A 179
VAL A  65
LEU A  60
 None
 1.15A 4qd3A-4a0sA:
undetectable		 4qd3A-4a0sA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a11 DNA EXCISION REPAIR
PROTEIN ERCC-8

(Homo sapiens) 		PF00400
(WD40) 		5 GLY B  66
HIS B  98
SER B  61
VAL B 105
LEU B  60
 None
 1.14A 4qd3A-4a11B:
undetectable		 4qd3A-4a11B:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5p PROTEIN MXIA

(Shigella
flexneri) 		PF00771
(FHIPEP) 		5 LEU A 538
GLY A 499
VAL A 394
VAL A 544
LEU A 547
 None
 1.18A 4qd3A-4a5pA:
undetectable		 4qd3A-4a5pA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ade SUCCINYLORNITHINE
TRANSAMINASE

(Escherichia
coli) 		PF00202
(Aminotran_3) 		5 LEU A  60
GLY A 257
VAL A 291
VAL A 295
LEU A 296
 None
 1.09A 4qd3A-4adeA:
undetectable		 4qd3A-4adeA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avr PA4485

(Pseudomonas
aeruginosa) 		PF03330
(DPBB_1) 		5 GLY A  80
ASN A  49
VAL A  53
SER A  52
VAL A  44
 None
 1.22A 4qd3A-4avrA:
undetectable		 4qd3A-4avrA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bsq CATHEPSIN S

(Mus musculus) 		PF00112
(Peptidase_C1) 		5 LEU A 247
GLY A 293
VAL A 257
SER A 258
VAL A 259
 None
 1.17A 4qd3A-4bsqA:
undetectable		 4qd3A-4bsqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ev4 CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1

(Serratia
fonticola) 		PF13354
(Beta-lactamase2) 		5 LEU A  33
GLY A  45
SER A 283
VAL A 286
LEU A 287
 None
 1.00A 4qd3A-4ev4A:
undetectable		 4qd3A-4ev4A:
20.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fno PEPTIDYL-TRNA
HYDROLASE

(Pseudomonas
aeruginosa) 		PF01195
(Pept_tRNA_hydro) 		9 HIS A  22
LEU A  97
GLY A 114
HIS A 115
ASN A 116
VAL A 147
SER A 148
VAL A 151
LEU A 152
 None
 0.39A 4qd3A-4fnoA:
39.4		 4qd3A-4fnoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fuu LEUCINE
AMINOPEPTIDASE

(Bacteroides
thetaiotaomicron) 		PF04389
(Peptidase_M28) 		5 LEU A 222
GLY A 155
VAL A 319
VAL A 323
LEU A 324
 None
 1.15A 4qd3A-4fuuA:
5.6		 4qd3A-4fuuA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxd DNA POLYMERASE ALPHA
CATALYTIC SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		5 LEU A1110
VAL A1085
SER A1086
VAL A1089
LEU A1090
 None
 0.87A 4qd3A-4fxdA:
undetectable		 4qd3A-4fxdA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4guz PROBABLE ARYLAMINE
N-ACETYL TRANSFERASE

(Mycobacteroides
abscessus) 		PF00797
(Acetyltransf_2) 		5 LEU A  32
GLY A  35
HIS A  36
VAL A  83
LEU A   7
 None
 1.08A 4qd3A-4guzA:
undetectable		 4qd3A-4guzA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gz8 SEMAPHORIN-3A

(Mus musculus) 		PF01403
(Sema) 		5 GLY A 508
ASN A  49
VAL A 482
VAL A  45
LEU A  40
 None
 1.15A 4qd3A-4gz8A:
undetectable		 4qd3A-4gz8A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h5y LIDA PROTEIN,
SUBSTRATE OF THE
DOT/ICM SYSTEM

(Legionella
pneumophila) 		no annotation 5 LEU A 247
GLY A 433
ASN A 435
VAL A 542
VAL A 538
 None
 1.06A 4qd3A-4h5yA:
undetectable		 4qd3A-4h5yA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hnh NAD-DEPENDENT
EPIMERASE/DEHYDRATAS
E

(Veillonella
parvula) 		PF13460
(NAD_binding_10) 		5 LEU A 151
GLY A 102
VAL A 182
VAL A 205
LEU A 165
 NAP  A 301 ( 4.4A)
None
None
None
None
 1.16A 4qd3A-4hnhA:
3.0		 4qd3A-4hnhA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpz DTALE2

(Xanthomonas) 		PF03377
(TAL_effector) 		5 GLY A 356
HIS A 355
VAL A 397
VAL A 378
LEU A 375
 None
 1.21A 4qd3A-4hpzA:
undetectable		 4qd3A-4hpzA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpz DTALE2

(Xanthomonas) 		PF03377
(TAL_effector) 		5 GLY A 390
HIS A 389
VAL A 431
VAL A 412
LEU A 409
 None
 1.18A 4qd3A-4hpzA:
undetectable		 4qd3A-4hpzA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j07 6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE

(Mycobacterium
leprae) 		PF00885
(DMRL_synthase) 		5 LEU A 101
GLY A 115
VAL A 112
VAL A  66
LEU A  69
 None
 1.05A 4qd3A-4j07A:
undetectable		 4qd3A-4j07A:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lan URACIL-5-CARBOXYLATE
DECARBOXYLASE

(Cordyceps
militaris) 		PF04909
(Amidohydro_2) 		5 LEU A 373
GLY A 364
VAL A  91
SER A  92
VAL A  93
 None
 1.13A 4qd3A-4lanA:
undetectable		 4qd3A-4lanA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnb OBCA, OXALATE
BIOSYNTHETIC
COMPONENT A

(Burkholderia
glumae) 		PF05853
(BKACE) 		5 LEU A 435
ASN A 355
VAL A 347
VAL A 345
LEU A 309
 None
 1.21A 4qd3A-4nnbA:
undetectable		 4qd3A-4nnbA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8f VACUOLAR
AMINOPEPTIDASE 1

(Saccharomyces
cerevisiae) 		PF02127
(Peptidase_M18) 		5 LEU A 368
GLY A 428
VAL A 397
VAL A 386
LEU A 389
 None
 1.16A 4qd3A-4r8fA:
4.8		 4qd3A-4r8fA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ro1 DIS3-LIKE
EXONUCLEASE 2

(Schizosaccharomyces
pombe) 		no annotation 5 LEU B 408
GLY B 412
VAL B 814
SER B 811
VAL B 504
 None
 1.16A 4qd3A-4ro1B:
undetectable		 4qd3A-4ro1B:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u7b MARINER MOS1
TRANSPOSASE

(Drosophila
mauritiana) 		PF01359
(Transposase_1) 		5 LEU A 263
HIS A 254
ASN A 250
VAL A 270
LEU A 247
 None
 1.06A 4qd3A-4u7bA:
undetectable		 4qd3A-4u7bA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye4 HT593.1 GP120

(Human
immunodeficiency
virus) 		PF00516
(GP120) 		5 HIS G  66
LEU G 116
VAL G 208
SER G 209
VAL G  65
 None
 1.20A 4qd3A-4ye4G:
undetectable		 4qd3A-4ye4G:
16.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4yly PEPTIDYL-TRNA
HYDROLASE

(Staphylococcus
aureus) 		PF01195
(Pept_tRNA_hydro) 		8 HIS A  19
LEU A  93
GLY A 110
HIS A 111
ASN A 112
VAL A 142
VAL A 146
LEU A 147
 None
 0.71A 4qd3A-4ylyA:
28.3		 4qd3A-4ylyA:
31.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yuf CORB

(Corallococcus
coralloides) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		5 LEU A 231
GLY A 235
VAL A 326
SER A 327
LEU A 122
 None
 1.22A 4qd3A-4yufA:
undetectable		 4qd3A-4yufA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yyq FICIN ISOFORM A

(Ficus carica) 		PF00112
(Peptidase_C1) 		5 LEU A 122
GLY A 166
VAL A 131
SER A 132
VAL A 133
 None
 1.20A 4qd3A-4yyqA:
undetectable		 4qd3A-4yyqA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aoc ESTERASE

(Thermogutta
terrifontis) 		PF07859
(Abhydrolase_3) 		5 LEU A 141
GLY A 189
VAL A 195
VAL A  96
LEU A 131
 None
 1.11A 4qd3A-5aocA:
3.0		 4qd3A-5aocA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn7 PROTEIN FAM179B

(Mus musculus) 		no annotation 5 LEU A 461
GLY A 433
VAL A 428
VAL A 421
LEU A 420
 None
 1.22A 4qd3A-5dn7A:
undetectable		 4qd3A-5dn7A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4l ENVELOPE
GLYCOPROTEIN GP120
OF HIV-1 CLADE C

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		5 HIS A  66
LEU A 116
VAL A 208
SER A 209
VAL A  65
 None
 1.19A 4qd3A-5f4lA:
undetectable		 4qd3A-5f4lA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8p ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO

(Homo sapiens) 		PF12933
(FTO_NTD)
PF12934
(FTO_CTD) 		5 LEU A 356
GLY A 367
VAL A 413
VAL A 417
LEU A 418
 None
 1.17A 4qd3A-5f8pA:
undetectable		 4qd3A-5f8pA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lw7 ABC TRANSPORTER
ATP-BINDING PROTEIN

(Pyrococcus
abyssi) 		PF00005
(ABC_tran)
PF00037
(Fer4)
PF04068
(RLI) 		5 LEU B 215
GLY B 218
VAL B 207
VAL B 182
LEU B 186
 None
 1.22A 4qd3A-5lw7B:
undetectable		 4qd3A-5lw7B:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te7 HIV-1 GP120 CORE

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		5 HIS G  66
LEU G 116
VAL G 208
SER G 209
VAL G  65
 None
 1.09A 4qd3A-5te7G:
undetectable		 4qd3A-5te7G:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5urp TOXIN 2A

(Paenibacillus
larvae) 		no annotation 5 LEU A 131
GLY A 155
VAL A  79
VAL A  81
LEU A 146
 None
 1.07A 4qd3A-5urpA:
undetectable		 4qd3A-5urpA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wsy UNCHARACTERIZED
PROTEIN

(Streptomyces
avermitilis) 		PF10862
(FcoT) 		5 GLY A  88
VAL A  81
SER A  80
VAL A  77
LEU A  76
 None
 1.11A 4qd3A-5wsyA:
undetectable		 4qd3A-5wsyA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x5l ADER

(Acinetobacter
baumannii) 		PF00486
(Trans_reg_C) 		5 LEU A 192
GLY A 234
ASN A 229
VAL A 207
VAL A 211
 LEU  A 192 ( 0.6A)
GLY  A 234 ( 0.0A)
ASN  A 229 ( 0.6A)
VAL  A 207 ( 0.6A)
VAL  A 211 ( 0.6A)
 0.98A 4qd3A-5x5lA:
undetectable		 4qd3A-5x5lA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yac TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5B

(Pyrococcus
abyssi) 		PF02475
(Met_10) 		5 LEU A  19
GLY A  48
VAL A   5
VAL A  42
LEU A   3
 None
 1.02A 4qd3A-5yacA:
undetectable		 4qd3A-5yacA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydp TETR TRANSCRIPTIONAL
REGULATORY PROTEIN

(Dietzia sp.
DQ12-45-1b) 		PF00440
(TetR_N) 		5 LEU A  67
GLY A  76
VAL A  35
VAL A  56
LEU A  42
 None
 1.22A 4qd3A-5ydpA:
undetectable		 4qd3A-5ydpA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yv5 ATPASE RIL

(Pyrococcus
furiosus) 		no annotation 5 LEU A 211
GLY A 214
VAL A 203
VAL A 178
LEU A 182
 None
 1.17A 4qd3A-5yv5A:
undetectable		 4qd3A-5yv5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zzn -

(-) 		no annotation 5 LEU U  27
ASN U  78
VAL U  58
VAL U  61
LEU U  62
 None
 1.20A 4qd3A-5zznU:
undetectable		 4qd3A-5zznU:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6a31 PEPTIDYL-TRNA
HYDROLASE

(Acinetobacter
baumannii) 		no annotation 9 HIS A  22
LEU A  97
GLY A 114
HIS A 115
ASN A 116
VAL A 145
SER A 146
VAL A 149
LEU A 150
 None
 0.70A 4qd3A-6a31A:
34.1		 4qd3A-6a31A:
31.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brd RIFAMPIN
MONOOXYGENASE

(Streptomyces
venezuelae) 		no annotation 5 HIS A 282
GLY A 293
VAL A 327
VAL A 331
LEU A 332
 None
 1.01A 4qd3A-6brdA:
undetectable		 4qd3A-6brdA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eno DEHYDRATASE FAMILY
PROTEIN

(Carboxydothermus
hydrogenoformans) 		no annotation 5 HIS A  17
GLY A  54
HIS A  53
VAL A  12
LEU A  14
 None
None
GOL  A 503 (-3.9A)
None
None
 1.18A 4qd3A-6enoA:
undetectable		 4qd3A-6enoA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6enz ACIDIC AMINO ACID
DECARBOXYLASE GADL1

(Mus musculus) 		no annotation 5 LEU A 316
GLY A 287
VAL A 291
SER A 292
VAL A 390
 None
 1.10A 4qd3A-6enzA:
undetectable		 4qd3A-6enzA:
14.87