SIMILAR PATTERNS OF AMINO ACIDS FOR 4Q56_A_ACTA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ag4 EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		4 ASN A 325
ARG A 296
HIS A 291
ASN A 289
 None
 1.34A 4q56A-4ag4A:
0.0		 4q56A-4ag4A:
13.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4q56 HELIX ASPERSA
AGGLUTININ (HAA)

(Helix aspersa) 		PF09458
(H_lectin) 		4 ASN A  62
ARG A  64
HIS A  85
ASN A  86
 A2G  A 202 ( 3.8A)
A2G  A 202 ( 3.8A)
ZN  A 210 (-3.2A)
ACT  A 201 (-3.5A)
 0.00A 4q56A-4q56A:
22.0		 4q56A-4q56A:
100.00