SIMILAR PATTERNS OF AMINO ACIDS FOR 4PWD_C_NVPC901_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0r PHOSDUCIN

(Bos taurus) 		PF02114
(Phosducin) 		4 LEU P 158
VAL P 137
VAL P 114
LEU P 227
 None
 1.04A 4pwdC-1a0rP:
undetectable		 4pwdC-1a0rP:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8o ICE INHIBITOR

(Cowpox virus) 		PF00079
(Serpin) 		4 LEU A  27
VAL A 258
LEU A 250
TYR A  45
 None
 1.09A 4pwdC-1c8oA:
undetectable		 4pwdC-1c8oA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fxl PARANEOPLASTIC
ENCEPHALOMYELITIS
ANTIGEN HUD

(Homo sapiens) 		PF00076
(RRM_1) 		4 LEU A  58
VAL A 112
VAL A  85
LEU A 103
 None
 1.08A 4pwdC-1fxlA:
2.7		 4pwdC-1fxlA:
15.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1har HIV-1 REVERSE
TRANSCRIPTASE
(FINGERS AND PALM
SUBDOMAINS)

(Human
immunodeficiency
virus 1) 		PF00078
(RVT_1) 		4 VAL A 106
VAL A 179
TYR A 181
TYR A 188
 None
 0.59A 4pwdC-1harA:
12.4		 4pwdC-1harA:
94.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2l 4-AMINO-4-DEOXYCHORI
SMATE LYASE

(Escherichia
coli) 		PF01063
(Aminotran_4) 		4 LEU A 163
VAL A 244
TRP A 181
LEU A 179
 None
 1.11A 4pwdC-1i2lA:
0.0		 4pwdC-1i2lA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl0 S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROENZYME

(Homo sapiens) 		PF01536
(SAM_decarbox) 		4 LEU A  79
TYR A  63
TRP A  40
LEU A  44
 None
 1.13A 4pwdC-1jl0A:
2.5		 4pwdC-1jl0A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jpl ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA3

(Homo sapiens) 		PF00790
(VHS) 		4 LEU A 118
VAL A  97
VAL A 144
LEU A  93
 None
 1.04A 4pwdC-1jplA:
undetectable		 4pwdC-1jplA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8y PROTOONCOPROTEIN

(Rattus
norvegicus) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 LEU C  92
VAL C  58
TRP C 184
LEU C 119
 None
 1.01A 4pwdC-1n8yC:
0.0		 4pwdC-1n8yC:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlf REGULATORY PROTEIN
REPA

(Escherichia
coli) 		PF13481
(AAA_25) 		4 VAL A 102
VAL A  71
TYR A  73
LEU A  90
 None
 0.97A 4pwdC-1nlfA:
undetectable		 4pwdC-1nlfA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o1y CONSERVED
HYPOTHETICAL PROTEIN
TM1158

(Thermotoga
maritima) 		PF00117
(GATase) 		4 LEU A  73
VAL A  49
TYR A  46
LEU A  31
 None
 1.00A 4pwdC-1o1yA:
undetectable		 4pwdC-1o1yA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pwe L-SERINE DEHYDRATASE

(Rattus
norvegicus) 		PF00291
(PALP) 		4 LEU A 274
VAL A  27
VAL A 164
TYR A 278
 None
 0.74A 4pwdC-1pweA:
undetectable		 4pwdC-1pweA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q7h CONSERVED
HYPOTHETICAL PROTEIN

(Thermoplasma
acidophilum) 		PF01472
(PUA)
PF09183
(DUF1947) 		4 LEU A  84
VAL A  60
VAL A 109
TYR A 115
 None
 1.09A 4pwdC-1q7hA:
undetectable		 4pwdC-1q7hA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfv PYRIDOXAL KINASE

(Ovis aries) 		PF08543
(Phos_pyr_kin) 		4 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 0.99A 4pwdC-1rfvA:
undetectable		 4pwdC-1rfvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sh8 HYPOTHETICAL PROTEIN
PA5026

(Pseudomonas
aeruginosa) 		PF14539
(DUF4442) 		4 LEU A 123
VAL A  34
VAL A  97
LEU A 101
 None
 1.10A 4pwdC-1sh8A:
undetectable		 4pwdC-1sh8A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t4a PURS

(Bacillus
subtilis) 		PF02700
(PurS) 		4 VAL A   8
TYR A  76
TYR A  74
LEU A  66
 None
 1.00A 4pwdC-1t4aA:
undetectable		 4pwdC-1t4aA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ujj ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1

(Homo sapiens) 		PF00790
(VHS) 		4 LEU A 119
VAL A  98
VAL A 145
LEU A  94
 None
 1.08A 4pwdC-1ujjA:
undetectable		 4pwdC-1ujjA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmi HYPOTHETICAL PROTEIN
PHS013

(Pyrococcus
horikoshii) 		PF05016
(ParE_toxin) 		4 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.95A 4pwdC-1wmiA:
undetectable		 4pwdC-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvt CROTONOBETAINYL-COA:
CARNITINE
COA-TRANSFERASE

(Escherichia
coli) 		PF02515
(CoA_transf_3) 		4 LEU A 181
VAL A  17
TRP A  36
LEU A  12
 None
 0.74A 4pwdC-1xvtA:
undetectable		 4pwdC-1xvtA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yhu HEMOGLOBIN A1 CHAIN

(Riftia
pachyptila) 		PF00042
(Globin) 		4 LEU A  72
VAL A 117
TYR A 134
LEU A  33
 HEM  A 160 (-4.5A)
None
None
None
 1.00A 4pwdC-1yhuA:
undetectable		 4pwdC-1yhuA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl6 BOTULINUM NEUROTOXIN
TYPE E

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 274
VAL A 318
TYR A 306
LEU A 330
 None
 0.89A 4pwdC-1zl6A:
undetectable		 4pwdC-1zl6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2n GIANT HEMOGLOBIN,
A1(B) GLOBIN CHAIN

(Oligobrachia
mashikoi) 		PF00042
(Globin) 		4 LEU A  70
VAL A 115
TYR A 131
LEU A  31
 HEM  A 200 ( 4.6A)
None
None
None
 0.98A 4pwdC-2d2nA:
undetectable		 4pwdC-2d2nA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eae ALPHA-FUCOSIDASE

(Bifidobacterium
bifidum) 		PF14498
(Glyco_hyd_65N_2) 		4 LEU A 143
VAL A 267
LEU A 194
TYR A 145
 None
 1.03A 4pwdC-2eaeA:
undetectable		 4pwdC-2eaeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hih LIPASE 46 KDA FORM

(Staphylococcus
hyicus) 		no annotation 4 LEU A 133
VAL A  64
TYR A  79
LEU A 158
 None
 1.04A 4pwdC-2hihA:
undetectable		 4pwdC-2hihA:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus 1) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		7 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.61A 4pwdC-2hnzA:
36.6		 4pwdC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus 1) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		7 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
 0.63A 4pwdC-2hnzA:
36.6		 4pwdC-2hnzA:
98.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuy GLYCOSYLTRANSFERASE

(Streptomyces
viridochromogenes) 		PF00534
(Glycos_transf_1) 		4 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 1.07A 4pwdC-2iuyA:
undetectable		 4pwdC-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kbg NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF00041
(fn3) 		4 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 0.99A 4pwdC-2kbgA:
undetectable		 4pwdC-2kbgA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE

(Escherichia
coli) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
PF13292
(DXP_synthase_N) 		4 LEU A 506
VAL A 521
TRP A 618
LEU A 619
 None
 1.12A 4pwdC-2o1sA:
undetectable		 4pwdC-2o1sA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rkb SERINE
DEHYDRATASE-LIKE

(Homo sapiens) 		PF00291
(PALP) 		4 LEU A 280
VAL A  34
VAL A 170
TYR A 284
 None
 0.75A 4pwdC-2rkbA:
1.6		 4pwdC-2rkbA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wvw RBCX PROTEIN

(Anabaena sp. CA
= ATCC 33047) 		PF02341
(RcbX) 		4 LEU I  59
VAL I  26
TRP I  40
TYR I  55
 None
 1.11A 4pwdC-2wvwI:
undetectable		 4pwdC-2wvwI:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr7 MALONYLTRANSFERASE

(Nicotiana
tabacum) 		PF02458
(Transferase) 		4 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.93A 4pwdC-2xr7A:
3.0		 4pwdC-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z06 PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0625

(Thermus
thermophilus) 		PF13277
(YmdB) 		4 LEU A 128
VAL A 166
VAL A 140
LEU A 155
 None
 1.06A 4pwdC-2z06A:
undetectable		 4pwdC-2z06A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbk TYPE II DNA
TOPOISOMERASE VI
SUBUNIT A

(Sulfolobus
shibatae) 		PF04406
(TP6A_N) 		4 LEU A 248
VAL A 163
VAL A 207
LEU A 167
 None
 1.09A 4pwdC-2zbkA:
undetectable		 4pwdC-2zbkA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c87 ENTEROCHELIN
ESTERASE

(Shigella
flexneri) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 LEU A 384
VAL A 276
VAL A 338
LEU A 199
 None
 1.11A 4pwdC-3c87A:
undetectable		 4pwdC-3c87A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dja PROTEIN CT_858

(Chlamydia
trachomatis) 		PF03572
(Peptidase_S41) 		4 LEU A 430
VAL A 420
TRP A 413
LEU A 416
 None
 1.10A 4pwdC-3djaA:
undetectable		 4pwdC-3djaA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epf PROTEIN VP1

(Enterovirus C) 		PF00073
(Rhv) 		4 VAL 1 242
VAL 1 183
TYR 1 185
TYR 1 155
 None
 0.61A 4pwdC-3epf1:
undetectable		 4pwdC-3epf1:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhx PYRIDOXAL KINASE

(Homo sapiens) 		PF08543
(Phos_pyr_kin) 		4 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 1.05A 4pwdC-3fhxA:
undetectable		 4pwdC-3fhxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ius UNCHARACTERIZED
CONSERVED PROTEIN

(Ruegeria
pomeroyi) 		no annotation 4 LEU A  98
VAL A 204
TRP A  94
LEU A 189
 None
 1.11A 4pwdC-3iusA:
undetectable		 4pwdC-3iusA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C) 		PF06016
(Reovirus_L2) 		4 LEU W1250
VAL W1271
VAL W1237
TYR W1287
 None
 1.01A 4pwdC-3iylW:
undetectable		 4pwdC-3iylW:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iz4 SSRA-BINDING PROTEIN

(Escherichia
coli) 		PF01668
(SmpB) 		4 LEU B  53
VAL B 115
TYR B  20
LEU B  86
 None
 1.01A 4pwdC-3iz4B:
undetectable		 4pwdC-3iz4B:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jzj ACARBOSE/MALTOSE
BINDING PROTEIN GACH

(Streptomyces
glaucescens) 		PF13416
(SBP_bac_8) 		4 VAL A  52
VAL A  79
TYR A  54
TYR A 310
 None
 0.97A 4pwdC-3jzjA:
1.4		 4pwdC-3jzjA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n3k UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 8

(Homo sapiens) 		PF00443
(UCH) 		4 LEU A1104
VAL A1096
LEU A 964
TYR A1106
 None
 1.10A 4pwdC-3n3kA:
undetectable		 4pwdC-3n3kA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ns4 VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 53

(Saccharomyces
cerevisiae) 		PF16854
(VPS53_C) 		4 LEU A 680
VAL A 619
LEU A 707
TYR A 686
 None
 0.95A 4pwdC-3ns4A:
undetectable		 4pwdC-3ns4A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sll PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE

(Mycobacteroides
abscessus) 		PF00378
(ECH_1) 		4 LEU A 195
VAL A 128
LEU A  15
TYR A 199
 None
 0.91A 4pwdC-3sllA:
undetectable		 4pwdC-3sllA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tot GLUTATHIONE
S-TRANSFERASE
PROTEIN

(Ralstonia
solanacearum) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 LEU A  54
VAL A  67
TYR A  71
LEU A  21
 None
 1.13A 4pwdC-3totA:
undetectable		 4pwdC-3totA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujh GLUCOSE-6-PHOSPHATE
ISOMERASE

(Toxoplasma
gondii) 		PF00342
(PGI) 		4 LEU A 317
VAL A 500
VAL A  78
LEU A 327
 None
 1.05A 4pwdC-3ujhA:
undetectable		 4pwdC-3ujhA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsv XYLOSIDASE

(Thermoanaerobacterium
saccharolyticum) 		PF13229
(Beta_helix) 		4 VAL A  89
VAL A 171
TYR A 173
TYR A 184
 None
 0.46A 4pwdC-3vsvA:
undetectable		 4pwdC-3vsvA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wct A1 GLOBIN CHAIN OF
GIANT V2 HEMOGLOBIN

(Lamellibrachia
satsuma) 		PF00042
(Globin) 		4 LEU A  70
VAL A 115
TYR A 132
LEU A  31
 HEM  A 200 ( 4.6A)
None
None
None
 0.90A 4pwdC-3wctA:
2.4		 4pwdC-3wctA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 LEU A 326
VAL A 368
TYR A 365
LEU A 252
 None
 1.06A 4pwdC-3x1lA:
1.7		 4pwdC-3x1lA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0h ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF00202
(Aminotran_3)
PF13500
(AAA_26) 		4 VAL A 780
VAL A 736
TYR A 782
TRP A 370
 None
None
None
KAP  A1808 ( 4.8A)
 1.08A 4pwdC-4a0hA:
2.9		 4pwdC-4a0hA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4csw CUPIN 4 FAMILY
PROTEIN

(Rhodothermus
marinus) 		PF08007
(Cupin_4) 		4 VAL A 121
TYR A 123
TRP A  87
LEU A  57
 None
UN9  A1391 ( 4.8A)
None
None
 0.89A 4pwdC-4cswA:
undetectable		 4pwdC-4cswA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dlq LATROPHILIN-1

(Rattus
norvegicus) 		PF01825
(GPS)
PF02793
(HRM)
PF16489
(GAIN) 		4 VAL A 679
VAL A 620
TRP A 636
LEU A 733
 None
 0.98A 4pwdC-4dlqA:
undetectable		 4pwdC-4dlqA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e16 PRECORRIN-4
C(11)-METHYLTRANSFER
ASE

(Clostridioides
difficile) 		PF00590
(TP_methylase) 		4 LEU A 230
VAL A 127
TYR A 125
LEU A 121
 None
 1.07A 4pwdC-4e16A:
undetectable		 4pwdC-4e16A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ed5 ELAV-LIKE PROTEIN 1

(Homo sapiens) 		PF00076
(RRM_1) 		4 LEU A  39
VAL A  93
VAL A  66
LEU A  84
 None
 1.08A 4pwdC-4ed5A:
2.9		 4pwdC-4ed5A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxv ELAV-LIKE PROTEIN 1

(Homo sapiens) 		PF00076
(RRM_1) 		4 LEU A  39
VAL A  93
VAL A  66
LEU A  84
 None
 1.12A 4pwdC-4fxvA:
2.6		 4pwdC-4fxvA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lih GAMMA-GLUTAMYL-GAMMA
-AMINOBUTYRALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 LEU A 404
VAL A 366
VAL A 388
LEU A 321
 None
 1.07A 4pwdC-4lihA:
undetectable		 4pwdC-4lihA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ln9 RIFAMYCIN POLYKETIDE
SYNTHASE

(Amycolatopsis
mediterranei) 		PF14765
(PS-DH) 		4 LEU A 219
VAL A 262
VAL A 284
LEU A 223
 None
 1.03A 4pwdC-4ln9A:
undetectable		 4pwdC-4ln9A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mhb PUTATIVE ALDO/KETO
REDUCTASE

(Yersinia pestis) 		PF00248
(Aldo_ket_red) 		4 LEU A  89
VAL A 127
TYR A  95
TYR A 118
 None
 1.05A 4pwdC-4mhbA:
undetectable		 4pwdC-4mhbA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2c CRISPR-ASSOCIATED
HELICASE CAS3

(Thermobaculum
terrenum) 		PF00271
(Helicase_C) 		4 LEU A  91
VAL A  82
TRP A  72
LEU A 229
 None
 1.11A 4pwdC-4q2cA:
undetectable		 4pwdC-4q2cA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qpv UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF07901
(DUF1672) 		4 LEU A 247
TYR A 197
LEU A 167
TYR A 176
 None
 1.08A 4pwdC-4qpvA:
undetectable		 4pwdC-4qpvA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8l UNCHARACTERIZED
PROTEIN

(Cavia porcellus) 		PF00710
(Asparaginase) 		4 LEU A  13
TYR A  15
LEU A  39
TYR A  74
 None
 0.85A 4pwdC-4r8lA:
undetectable		 4pwdC-4r8lA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8y CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		4 LEU A 326
VAL A 368
TYR A 365
LEU A 252
 None
 1.04A 4pwdC-4w8yA:
4.0		 4pwdC-4w8yA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyi KINETOCHORE PROTEIN
MIS16

(Schizosaccharomyces
japonicus) 		PF00400
(WD40)
PF12265
(CAF1C_H4-bd) 		4 LEU A 318
VAL A 325
TRP A 330
LEU A 305
 None
 1.12A 4pwdC-4xyiA:
undetectable		 4pwdC-4xyiA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zcs CHOLINE-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Plasmodium
falciparum) 		PF01467
(CTP_transf_like) 		4 LEU A 699
VAL A 619
TYR A 621
LEU A 744
 None
 0.85A 4pwdC-4zcsA:
undetectable		 4pwdC-4zcsA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aee ALPHA-GLUCOSIDASE
YIHQ

(Escherichia
coli) 		PF01055
(Glyco_hydro_31) 		4 LEU A 568
VAL A 660
TYR A 662
LEU A 675
 None
 0.96A 4pwdC-5aeeA:
undetectable		 4pwdC-5aeeA:
21.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5c24 HIV-1 REVERSE
TRANSCRIPTASE, P51
SUBUNIT

(Human
immunodeficiency
virus 1) 		PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		4 VAL B 106
VAL B 179
TYR B 181
TYR B 188
 None
 0.41A 4pwdC-5c24B:
10.4		 4pwdC-5c24B:
96.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chv UBL
CARBOXYL-TERMINAL
HYDROLASE 18

(Mus musculus) 		PF00443
(UCH) 		4 LEU A 361
VAL A 343
LEU A 206
TYR A 363
 None
 1.01A 4pwdC-5chvA:
undetectable		 4pwdC-5chvA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5com PUTATIVE CONJUGATIVE
TRANSPOSON PROTEIN
TN1549-LIKE,
CTN5-ORF2

(Clostridioides
difficile) 		PF08020
(DUF1706) 		4 LEU A  68
VAL A  82
TRP A 100
LEU A  97
 None
 0.90A 4pwdC-5comA:
undetectable		 4pwdC-5comA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cx7 ATP:COB(I)ALAMIN
ADENOSYLTRANSFERASE

(Salmonella
enterica) 		PF03928
(Haem_degrading) 		4 LEU A  20
VAL A  48
VAL A  37
LEU A  12
 None
 1.01A 4pwdC-5cx7A:
undetectable		 4pwdC-5cx7A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dgg UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 4 LEU A 224
VAL A 187
LEU A 148
TYR A 220
 None
 0.74A 4pwdC-5dggA:
undetectable		 4pwdC-5dggA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dne L-ASPARAGINASE

(Cavia porcellus) 		PF00710
(Asparaginase) 		4 LEU A  13
TYR A  15
LEU A  39
TYR A  74
 None
 0.89A 4pwdC-5dneA:
undetectable		 4pwdC-5dneA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fby CLEAVED PEPTIDE
SEPARASE

(Chaetomium
thermophilum;
synthetic
construct) 		PF03568
(Peptidase_C50)
no annotation 		4 LEU A1733
VAL A1710
TYR A1706
LEU B  16
 None
 0.93A 4pwdC-5fbyA:
undetectable		 4pwdC-5fbyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg9 PROTEASOME SUBUNIT
BETA TYPE-2

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome)
PF12465
(Pr_beta_C) 		4 LEU H 154
VAL H   4
TYR H 124
LEU H 146
 None
 0.68A 4pwdC-5fg9H:
undetectable		 4pwdC-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg9 PROTEASOME SUBUNIT
BETA TYPE-2

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome)
PF12465
(Pr_beta_C) 		4 LEU H 154
VAL H  13
VAL H   4
LEU H 146
 None
 0.99A 4pwdC-5fg9H:
undetectable		 4pwdC-5fg9H:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gvi UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30

(Danio rerio) 		PF00443
(UCH) 		4 LEU A 487
VAL A 479
LEU A 262
TYR A 489
 None
 1.00A 4pwdC-5gviA:
undetectable		 4pwdC-5gviA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hca CALRETICULIN,CALRETI
CULIN

(Entamoeba
histolytica) 		no annotation 4 TYR C 175
TRP C 193
LEU C 300
TYR C 303
 None
 0.95A 4pwdC-5hcaC:
undetectable		 4pwdC-5hcaC:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hct ENDOTHIAPEPSIN

(Cryphonectria
parasitica) 		PF00026
(Asp) 		4 LEU A  41
VAL A  96
VAL A 101
LEU A  32
 None
 0.89A 4pwdC-5hctA:
undetectable		 4pwdC-5hctA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hkq CDII IMMUNITY
PROTEIN

(Escherichia
coli) 		no annotation 4 VAL I  73
VAL I  83
TYR I  22
TYR I  10
 None
 0.94A 4pwdC-5hkqI:
undetectable		 4pwdC-5hkqI:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6h ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		4 LEU A1204
VAL A1255
VAL A1192
LEU A1285
 None
 1.10A 4pwdC-5i6hA:
undetectable		 4pwdC-5i6hA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6i ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN,ACETYL-COA
CARBOXYLASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF01039
(Carboxyl_trans)
PF08326
(ACC_central) 		4 LEU A1204
VAL A1255
VAL A1192
LEU A1285
 None
 1.07A 4pwdC-5i6iA:
undetectable		 4pwdC-5i6iA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j6c PUTATIVE REDUCTASE

(Clostridioides
difficile) 		PF00881
(Nitroreductase) 		4 LEU A  63
VAL A 148
TYR A 135
LEU A 140
 None
 1.10A 4pwdC-5j6cA:
undetectable		 4pwdC-5j6cA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkp UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08238
(Sel1) 		4 LEU A 224
TYR A 240
LEU A 274
TYR A 250
 None
 0.98A 4pwdC-5jkpA:
undetectable		 4pwdC-5jkpA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jm0 ALPHA-MANNOSIDASE,AL
PHA-MANNOSIDASE,ALPH
A-MANNOSIDASE

(Saccharomyces
cerevisiae) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 LEU A 432
VAL A 538
VAL A 368
LEU A 495
 None
 1.00A 4pwdC-5jm0A:
undetectable		 4pwdC-5jm0A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqn ALIPHATIC AMIDASE

(Nesterenkonia
sp. AN1) 		PF00795
(CN_hydrolase) 		4 TYR A 146
TYR A 115
LEU A 171
TYR A 196
 None
 1.03A 4pwdC-5jqnA:
undetectable		 4pwdC-5jqnA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwz CELLULOSE-BINDING
FAMILY II

(Streptomyces
sp. SirexAA-E) 		PF02012
(BNR) 		4 LEU A 258
VAL A 306
TRP A 196
LEU A 260
 None
 0.83A 4pwdC-5jwzA:
undetectable		 4pwdC-5jwzA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lmz FLUORINASE

(Streptomyces
sp. MA37) 		PF01887
(SAM_adeno_trans) 		4 LEU A 126
VAL A 162
VAL A  87
TYR A 119
 None
 0.80A 4pwdC-5lmzA:
undetectable		 4pwdC-5lmzA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nhx OUTER MEMBRANE
PROTEIN A

(Klebsiella
pneumoniae) 		no annotation 4 LEU A  34
VAL A  50
VAL A 127
LEU A  10
 None
 1.12A 4pwdC-5nhxA:
undetectable		 4pwdC-5nhxA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5njl CELL SURFACE PROTEIN
(PUTATIVE S-LAYER
PROTEIN)

(Clostridioides
difficile) 		no annotation 4 LEU A 169
VAL A 151
TYR A 149
LEU A 219
 None
 1.10A 4pwdC-5njlA:
undetectable		 4pwdC-5njlA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o4g RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-2

(Homo sapiens) 		no annotation 4 LEU C  92
VAL C  58
TRP C 183
LEU C 118
 None
 1.12A 4pwdC-5o4gC:
undetectable		 4pwdC-5o4gC:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogz -

(-) 		no annotation 4 LEU A 401
VAL A 442
LEU A 379
TYR A 399
 None
 0.96A 4pwdC-5ogzA:
undetectable		 4pwdC-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohk UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE
30,UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE
30,UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 30

(Homo sapiens) 		PF00443
(UCH) 		4 LEU A 497
VAL A 489
LEU A 266
TYR A 499
 None
 1.11A 4pwdC-5ohkA:
undetectable		 4pwdC-5ohkA:
20.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ovn POL PROTEIN

(Feline
immunodeficiency
virus) 		no annotation 4 LEU A  99
VAL A 105
LEU A 233
TYR A 317
 None
 0.71A 4pwdC-5ovnA:
25.0		 4pwdC-5ovnA:
53.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5p60 ENDOTHIAPEPSIN

(Cryphonectria
parasitica) 		PF00026
(Asp) 		4 LEU A  41
VAL A  96
VAL A 101
LEU A  32
 None
 0.90A 4pwdC-5p60A:
undetectable		 4pwdC-5p60A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u70 POTASSIUM CHANNEL
SUBFAMILY T MEMBER 1

(Gallus gallus) 		PF03493
(BK_channel_a)
PF07885
(Ion_trans_2) 		4 LEU A 360
VAL A 408
VAL A 398
LEU A 355
 None
 1.12A 4pwdC-5u70A:
undetectable		 4pwdC-5u70A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v7q LSU RIBOSOMAL
PROTEIN L21P

(Mycobacterium
tuberculosis) 		PF00829
(Ribosomal_L21p) 		4 LEU R  38
VAL R  17
TYR R  15
LEU R  98
 None
 0.88A 4pwdC-5v7qR:
undetectable		 4pwdC-5v7qR:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vc1 L-SELECTIN

(Homo sapiens) 		PF00008
(EGF)
PF00059
(Lectin_C) 		4 VAL A  27
TYR A  49
TYR A   5
TYR A  37
 None
 1.11A 4pwdC-5vc1A:
undetectable		 4pwdC-5vc1A:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8p HOMOSERINE
O-ACETYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF00561
(Abhydrolase_1) 		4 LEU A 167
VAL A 319
VAL A 156
LEU A 338
 None
 1.03A 4pwdC-5w8pA:
undetectable		 4pwdC-5w8pA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wso NS3 HELICASE

(Pestivirus A) 		no annotation 4 LEU A 236
VAL A 347
VAL A 252
TYR A 317
 None
 1.04A 4pwdC-5wsoA:
undetectable		 4pwdC-5wsoA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU A1316
VAL A1120
TYR A1331
LEU A1342
 None
 1.11A 4pwdC-5xogA:
4.5		 4pwdC-5xogA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6chj DIACYLGLYCEROL
O-ACYLTRANSFERASE

(Marinobacter
hydrocarbonoclasticus) 		no annotation 4 LEU A  97
VAL A 401
TYR A 399
LEU A 439
 None
 0.93A 4pwdC-6chjA:
3.6		 4pwdC-6chjA:
10.09