SIMILAR PATTERNS OF AMINO ACIDS FOR 4PUO_C_NVPC901_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN

(Bos taurus) 		PF01161
(PBP) 		4 VAL A 123
VAL A  88
TYR A  63
LEU A  57
 None
 1.02A 4puoC-1a44A:
undetectable		 4puoC-1a44A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8g PROTEIN
(1-AMINOCYCLOPROPANE
-1-CARBOXYLATE
SYNTHASE)

(Malus domestica) 		PF00155
(Aminotran_1_2) 		4 LEU A 114
VAL A 267
TYR A 269
LEU A 116
 None
 0.92A 4puoC-1b8gA:
undetectable		 4puoC-1b8gA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ej6 LAMBDA1

(Reovirus sp.) 		no annotation 4 LEU B 262
TYR B 407
TYR B 403
LEU B 394
 None
 1.03A 4puoC-1ej6B:
undetectable		 4puoC-1ej6B:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eu8 TREHALOSE/MALTOSE
BINDING PROTEIN

(Thermococcus
litoralis) 		PF01547
(SBP_bac_1) 		5 LEU A 207
VAL A 181
VAL A 188
TRP A 203
LEU A 373
 None
 1.35A 4puoC-1eu8A:
1.7		 4puoC-1eu8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f2p AMINOPEPTIDASE

(Streptomyces
griseus) 		PF04389
(Peptidase_M28) 		4 VAL A 213
VAL A  79
TYR A 156
TRP A 128
 None
 0.86A 4puoC-1f2pA:
undetectable		 4puoC-1f2pA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE

(Alcaligenes
faecalis) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 LEU A 574
TYR A 143
LEU A 151
TYR A 578
 None
 0.88A 4puoC-1g8kA:
0.0		 4puoC-1g8kA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8p MAGNESIUM-CHELATASE
38 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF01078
(Mg_chelatase) 		4 LEU A  36
VAL A 106
VAL A 189
TYR A 149
 None
 0.98A 4puoC-1g8pA:
undetectable		 4puoC-1g8pA:
18.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1har HIV-1 REVERSE
TRANSCRIPTASE
(FINGERS AND PALM
SUBDOMAINS)

(Human
immunodeficiency
virus 1) 		PF00078
(RVT_1) 		4 VAL A 106
VAL A 179
TYR A 181
TYR A 188
 None
 0.57A 4puoC-1harA:
21.4		 4puoC-1harA:
94.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2

(Mus musculus) 		PF01161
(PBP) 		4 VAL A 124
VAL A  89
TYR A  64
LEU A  58
 None
 1.04A 4puoC-1kn3A:
undetectable		 4puoC-1kn3A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lc7 L-THREONINE-O-3-PHOS
PHATE DECARBOXYLASE

(Salmonella
enterica) 		PF00155
(Aminotran_1_2) 		5 LEU A 353
VAL A 338
VAL A 292
TYR A 336
LEU A 315
 None
 1.06A 4puoC-1lc7A:
undetectable		 4puoC-1lc7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lip LIPID TRANSFER
PROTEIN

(Hordeum vulgare) 		PF00234
(Tryp_alpha_amyl) 		4 LEU A  51
VAL A  17
LEU A  34
TYR A  79
 None
 0.95A 4puoC-1lipA:
undetectable		 4puoC-1lipA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lns X-PROLYL DIPEPTIDYL
AMINOPEPTIDASE

(Lactococcus
lactis) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C)
PF09168
(PepX_N) 		4 LEU A 273
VAL A 204
LEU A 369
TYR A 271
 None
 1.03A 4puoC-1lnsA:
undetectable		 4puoC-1lnsA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqt FPRA

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 LEU A 160
VAL A 223
VAL A 194
LEU A 212
 None
 0.90A 4puoC-1lqtA:
undetectable		 4puoC-1lqtA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m93 SERINE PROTEINASE
INHIBITOR 2

(Cowpox virus) 		PF00079
(Serpin) 		4 LEU A  27
VAL B 258
LEU B 250
TYR A  45
 None
 1.05A 4puoC-1m93A:
undetectable		 4puoC-1m93A:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nf2 PHOSPHATASE

(Thermotoga
maritima) 		PF08282
(Hydrolase_3) 		4 LEU A 198
VAL A   6
TYR A  36
LEU A  72
 None
 0.99A 4puoC-1nf2A:
2.1		 4puoC-1nf2A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlf REGULATORY PROTEIN
REPA

(Escherichia
coli) 		PF13481
(AAA_25) 		4 VAL A 102
VAL A  71
TYR A  73
LEU A  90
 None
 0.96A 4puoC-1nlfA:
undetectable		 4puoC-1nlfA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o1y CONSERVED
HYPOTHETICAL PROTEIN
TM1158

(Thermotoga
maritima) 		PF00117
(GATase) 		4 LEU A  73
VAL A  49
TYR A  46
LEU A  31
 None
 0.93A 4puoC-1o1yA:
undetectable		 4puoC-1o1yA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pwe L-SERINE DEHYDRATASE

(Rattus
norvegicus) 		PF00291
(PALP) 		4 LEU A 274
VAL A  27
VAL A 164
TYR A 278
 None
 0.81A 4puoC-1pweA:
undetectable		 4puoC-1pweA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzd COATOMER GAMMA
SUBUNIT

(Bos taurus) 		PF08752
(COP-gamma_platf)
PF16381
(Coatomer_g_Cpla) 		4 LEU A 830
VAL A 856
VAL A 869
LEU A 828
 None
 0.98A 4puoC-1pzdA:
3.3		 4puoC-1pzdA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfv PYRIDOXAL KINASE

(Ovis aries) 		PF08543
(Phos_pyr_kin) 		4 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 0.92A 4puoC-1rfvA:
undetectable		 4puoC-1rfvA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1si1 IRON BINDING PROTEIN
FBPA

(Mannheimia
haemolytica) 		PF13343
(SBP_bac_6) 		4 LEU A 253
VAL A  30
VAL A  54
TYR A 252
 None
 0.94A 4puoC-1si1A:
undetectable		 4puoC-1si1A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1te2 2-DEOXYGLUCOSE-6-P
PHOSPHATASE

(Escherichia
coli) 		PF13419
(HAD_2) 		4 LEU A 215
VAL A 207
VAL A 191
LEU A 220
 None
 1.01A 4puoC-1te2A:
undetectable		 4puoC-1te2A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txk GLUCANS BIOSYNTHESIS
PROTEIN G

(Escherichia
coli) 		PF04349
(MdoG) 		5 LEU A 312
VAL A 348
VAL A 337
TYR A 366
LEU A 350
 None
 1.46A 4puoC-1txkA:
undetectable		 4puoC-1txkA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1weh CONSERVED
HYPOTHETICAL PROTEIN
TT1887

(Thermus
thermophilus) 		PF03641
(Lysine_decarbox) 		4 LEU A   4
VAL A  28
VAL A  52
TYR A  25
 None
 1.02A 4puoC-1wehA:
undetectable		 4puoC-1wehA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wi5 RRP5 PROTEIN HOMOLOG

(Homo sapiens) 		PF00575
(S1) 		4 LEU A 203
VAL A 266
VAL A 217
LEU A 197
 None
 0.95A 4puoC-1wi5A:
undetectable		 4puoC-1wi5A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmi HYPOTHETICAL PROTEIN
PHS013

(Pyrococcus
horikoshii) 		PF05016
(ParE_toxin) 		4 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.95A 4puoC-1wmiA:
undetectable		 4puoC-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wsj RIBONUCLEASE HI

(Escherichia
coli) 		PF00075
(RNase_H) 		4 LEU A  56
VAL A   5
TRP A 118
LEU A 111
 None
 0.93A 4puoC-1wsjA:
15.3		 4puoC-1wsjA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wwz HYPOTHETICAL PROTEIN
PH1933

(Pyrococcus
horikoshii) 		PF00583
(Acetyltransf_1) 		4 LEU A  20
VAL A  71
VAL A  92
LEU A   9
 None
None
ACO  A1001 (-3.5A)
None
 1.04A 4puoC-1wwzA:
undetectable		 4puoC-1wwzA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x25 HYPOTHETICAL UPF0076
PROTEIN ST0811

(Sulfurisphaera
tokodaii) 		PF01042
(Ribonuc_L-PSP) 		4 LEU A  54
VAL A 120
VAL A  76
LEU A  68
 None
 1.04A 4puoC-1x25A:
undetectable		 4puoC-1x25A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xez HEMOLYSIN

(Vibrio cholerae) 		PF07968
(Leukocidin)
PF12563
(Hemolysin_N)
PF16458
(Beta-prism_lec) 		4 LEU A  96
VAL A 142
VAL A  80
TYR A  78
 None
 1.01A 4puoC-1xezA:
undetectable		 4puoC-1xezA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xip NUCLEOPORIN NUP159

(Saccharomyces
cerevisiae) 		PF16755
(NUP214) 		4 LEU A 174
VAL A 164
VAL A 218
LEU A 160
 None
 1.02A 4puoC-1xipA:
undetectable		 4puoC-1xipA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xvt CROTONOBETAINYL-COA:
CARNITINE
COA-TRANSFERASE

(Escherichia
coli) 		PF02515
(CoA_transf_3) 		4 LEU A 181
VAL A  17
TRP A  36
LEU A  12
 None
 0.72A 4puoC-1xvtA:
undetectable		 4puoC-1xvtA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzz INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 1

(Mus musculus) 		PF08709
(Ins145_P3_rec) 		4 LEU A 184
VAL A 209
VAL A 134
LEU A  17
 None
 1.01A 4puoC-1xzzA:
undetectable		 4puoC-1xzzA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yhu HEMOGLOBIN A1 CHAIN

(Riftia
pachyptila) 		PF00042
(Globin) 		5 LEU A  72
VAL A 117
VAL A  12
TYR A 134
LEU A  33
 HEM  A 160 (-4.5A)
None
None
None
None
 1.26A 4puoC-1yhuA:
2.2		 4puoC-1yhuA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl6 BOTULINUM NEUROTOXIN
TYPE E

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 274
VAL A 318
TYR A 306
LEU A 330
 None
 0.78A 4puoC-1zl6A:
undetectable		 4puoC-1zl6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a2j PYRIDOXAMINE
5'-PHOSPHATE OXIDASE

(Mycobacterium
tuberculosis) 		PF01243
(Putative_PNPOx)
PF10590
(PNP_phzG_C) 		4 LEU A  65
VAL A 127
VAL A  88
TYR A 191
 None
 1.04A 4puoC-2a2jA:
undetectable		 4puoC-2a2jA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag8 PYRROLINE-5-CARBOXYL
ATE REDUCTASE

(Neisseria
meningitidis) 		PF03807
(F420_oxidored)
PF14748
(P5CR_dimer) 		4 LEU A  85
VAL A   3
VAL A  15
LEU A  83
 None
 0.94A 4puoC-2ag8A:
undetectable		 4puoC-2ag8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2anc GUANYLATE KINASE

(Escherichia
coli) 		PF00625
(Guanylate_kin) 		4 LEU A  24
VAL A   9
VAL A  35
TYR A   7
 None
 0.93A 4puoC-2ancA:
undetectable		 4puoC-2ancA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7h HEMOGLOBIN BETA
CHAIN

(Cerdocyon thous) 		PF00042
(Globin) 		4 LEU B 110
VAL B 137
TYR B 130
TRP B  15
 None
 1.04A 4puoC-2b7hB:
undetectable		 4puoC-2b7hB:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bbu SUPPRESSOR OF
CYTOKINE SIGNALING 3

(Mus musculus) 		PF00017
(SH2) 		4 VAL A  55
VAL A 148
TYR A 137
LEU A  64
 None
 1.03A 4puoC-2bbuA:
undetectable		 4puoC-2bbuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4m GLYCOGEN
PHOSPHORYLASE

(Corynebacterium
callunae) 		PF00343
(Phosphorylase) 		4 LEU A 540
VAL A 557
VAL A 584
TYR A 536
 None
 1.01A 4puoC-2c4mA:
undetectable		 4puoC-2c4mA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c4t 5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE

(Streptomyces
cattleya) 		PF01887
(SAM_adeno_trans) 		4 LEU A 126
VAL A 162
VAL A  87
TYR A 119
 None
 0.82A 4puoC-2c4tA:
undetectable		 4puoC-2c4tA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cun PHOSPHOGLYCERATE
KINASE

(Pyrococcus
horikoshii) 		PF00162
(PGK) 		4 VAL A 145
VAL A  52
TYR A 143
TYR A  44
 None
 1.00A 4puoC-2cunA:
undetectable		 4puoC-2cunA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxh PROBABLE BRIX-DOMAIN
RIBOSOMAL BIOGENESIS
PROTEIN

(Aeropyrum
pernix) 		no annotation 4 LEU A  17
VAL A  85
TYR A  83
LEU A  55
 None
 1.02A 4puoC-2cxhA:
undetectable		 4puoC-2cxhA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxy BAF250B SUBUNIT

(Homo sapiens) 		PF01388
(ARID) 		4 LEU A  50
VAL A  78
TRP A  69
LEU A  72
 None
 0.78A 4puoC-2cxyA:
undetectable		 4puoC-2cxyA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d2n GIANT HEMOGLOBIN,
A1(B) GLOBIN CHAIN

(Oligobrachia
mashikoi) 		PF00042
(Globin) 		4 LEU A  70
VAL A 115
TYR A 131
LEU A  31
 HEM  A 200 ( 4.6A)
None
None
None
 0.97A 4puoC-2d2nA:
undetectable		 4puoC-2d2nA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eae ALPHA-FUCOSIDASE

(Bifidobacterium
bifidum) 		PF14498
(Glyco_hyd_65N_2) 		4 LEU A 143
VAL A 267
LEU A 194
TYR A 145
 None
 1.01A 4puoC-2eaeA:
undetectable		 4puoC-2eaeA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erc RRNA METHYL
TRANSFERASE

(Bacillus
subtilis) 		PF00398
(RrnaAD) 		4 LEU A 216
TYR A 203
TRP A 198
LEU A 235
 None
 0.96A 4puoC-2ercA:
undetectable		 4puoC-2ercA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hih LIPASE 46 KDA FORM

(Staphylococcus
hyicus) 		no annotation 4 LEU A 133
VAL A  64
TYR A  79
LEU A 158
 None
 1.00A 4puoC-2hihA:
undetectable		 4puoC-2hihA:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus 1) 		PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb) 		8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
 PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
 0.67A 4puoC-2hnzA:
36.5		 4puoC-2hnzA:
98.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hoe N-ACETYLGLUCOSAMINE
KINASE

(Thermotoga
maritima) 		PF00480
(ROK) 		4 LEU A 116
VAL A  82
LEU A 171
TYR A 120
 None
 0.92A 4puoC-2hoeA:
5.7		 4puoC-2hoeA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0z NAD(FAD)-UTILIZING
DEHYDROGENASES

(Bacillus cereus) 		PF03486
(HI0933_like) 		4 LEU A  15
VAL A 125
VAL A   7
LEU A 117
 None
 0.96A 4puoC-2i0zA:
undetectable		 4puoC-2i0zA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqx PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
1

(Rattus
norvegicus) 		PF01161
(PBP) 		4 VAL A 124
VAL A  89
TYR A  64
LEU A  58
 None
 1.03A 4puoC-2iqxA:
undetectable		 4puoC-2iqxA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuy GLYCOSYLTRANSFERASE

(Streptomyces
viridochromogenes) 		PF00534
(Glycos_transf_1) 		4 LEU A  53
VAL A  97
TYR A 338
LEU A  18
 None
 0.99A 4puoC-2iuyA:
undetectable		 4puoC-2iuyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran) 		4 LEU A1581
VAL A1605
TYR A1584
LEU A1566
 None
 0.98A 4puoC-2ix8A:
2.1		 4puoC-2ix8A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jbm NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Homo sapiens) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 VAL A 156
VAL A 149
TRP A  75
LEU A  56
 None
 1.02A 4puoC-2jbmA:
4.7		 4puoC-2jbmA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kbg NEURAL CELL ADHESION
MOLECULE 2

(Homo sapiens) 		PF00041
(fn3) 		4 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 1.02A 4puoC-2kbgA:
undetectable		 4puoC-2kbgA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kyz HEAVY METAL BINDING
PROTEIN

(Thermotoga
maritima) 		PF00403
(HMA) 		4 VAL A  61
VAL A  40
TYR A   3
TYR A  64
 None
 0.81A 4puoC-2kyzA:
5.7		 4puoC-2kyzA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p17 PIRIN-LIKE PROTEIN

(Geobacillus
kaustophilus) 		PF02678
(Pirin)
PF05726
(Pirin_C) 		4 LEU A 238
VAL A  88
LEU A 112
TYR A 240
 None
 1.01A 4puoC-2p17A:
undetectable		 4puoC-2p17A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1n TRANSPORT INHIBITOR
RESPONSE 1 PROTEIN

(Arabidopsis
thaliana) 		PF12937
(F-box-like) 		4 LEU B 163
VAL B 117
TRP B 175
LEU B 194
 None
 1.01A 4puoC-2p1nB:
undetectable		 4puoC-2p1nB:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1r LIPID KINASE YEGS

(Salmonella
enterica) 		PF00781
(DAGK_cat) 		4 LEU A   8
VAL A  73
TYR A  49
LEU A  56
 None
 0.94A 4puoC-2p1rA:
undetectable		 4puoC-2p1rA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfv EXOCYST COMPLEX
COMPONENT EXO70

(Saccharomyces
cerevisiae) 		PF03081
(Exo70) 		4 LEU A 260
TYR A 174
LEU A 202
TYR A 261
 None
 0.94A 4puoC-2pfvA:
undetectable		 4puoC-2pfvA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pkg SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
65 KDA REGULATORY
SUBUNIT A ALPHA
ISOFORM

(Homo sapiens) 		PF02985
(HEAT)
PF13646
(HEAT_2) 		4 LEU A 373
VAL A 419
TYR A 426
LEU A 404
 None
 1.00A 4puoC-2pkgA:
undetectable		 4puoC-2pkgA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q48 PROTEIN AT5G48480

(Arabidopsis
thaliana) 		no annotation 4 LEU A  77
TYR A  44
TRP A 150
LEU A 107
 None
 1.03A 4puoC-2q48A:
undetectable		 4puoC-2q48A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qik UPF0131 PROTEIN YKQA

(Bacillus
subtilis) 		PF06094
(GGACT)
PF13772
(AIG2_2) 		4 LEU A   5
VAL A  86
TYR A   8
LEU A  11
 None
 1.04A 4puoC-2qikA:
undetectable		 4puoC-2qikA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjc DIADENOSINE
TETRAPHOSPHATASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00149
(Metallophos) 		4 LEU A  34
VAL A  41
VAL A 244
LEU A  50
 None
 1.00A 4puoC-2qjcA:
undetectable		 4puoC-2qjcA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rb9 HYPE PROTEIN

(Escherichia
coli) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 LEU A 267
VAL A 231
VAL A 172
LEU A 324
 None
 1.04A 4puoC-2rb9A:
2.0		 4puoC-2rb9A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rkb SERINE
DEHYDRATASE-LIKE

(Homo sapiens) 		PF00291
(PALP) 		4 LEU A 280
VAL A  34
VAL A 170
TYR A 284
 None
 0.78A 4puoC-2rkbA:
undetectable		 4puoC-2rkbA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rkj TYROSYL-TRNA
SYNTHETASE

(Neurospora
crassa) 		PF00579
(tRNA-synt_1b) 		4 LEU A 117
VAL A 400
VAL A 177
LEU A 109
 None
 0.84A 4puoC-2rkjA:
undetectable		 4puoC-2rkjA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmb GENERAL SECRETION
PATHWAY PROTEIN F

(Vibrio cholerae) 		PF00482
(T2SSF) 		4 LEU A 118
VAL A  79
VAL A 149
LEU A  89
 None
 0.77A 4puoC-2vmbA:
undetectable		 4puoC-2vmbA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xlr FLAVIN-CONTAINING
MONOOXYGENASE

(Methylophaga
aminisulfidivorans) 		PF00743
(FMO-like) 		4 VAL A 164
TYR A 162
LEU A 347
TYR A 336
 None
 0.94A 4puoC-2xlrA:
undetectable		 4puoC-2xlrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr7 MALONYLTRANSFERASE

(Nicotiana
tabacum) 		PF02458
(Transferase) 		4 LEU A 256
VAL A 345
TYR A 276
LEU A 453
 None
 0.93A 4puoC-2xr7A:
2.6		 4puoC-2xr7A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ybq METHYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00590
(TP_methylase) 		4 LEU A  57
VAL A  23
VAL A  47
TRP A  38
 None
 1.03A 4puoC-2ybqA:
undetectable		 4puoC-2ybqA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyo SPRY
DOMAIN-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF00622
(SPRY) 		4 VAL A  58
VAL A  78
TYR A  80
TYR A  42
 None
 1.05A 4puoC-2yyoA:
undetectable		 4puoC-2yyoA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zo6 CYAN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN (KCY)

(Verrillofungia
concinna) 		PF01353
(GFP) 		4 LEU A  57
VAL A 199
VAL A 206
LEU A  50
 None
None
GYS  A  63 ( 4.9A)
None
 0.87A 4puoC-2zo6A:
undetectable		 4puoC-2zo6A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zo7 CYAN/GREEN-EMITTING
GFP-LIKE PROTEIN,
KUSABIRA-CYAN MUTANT
(KCY-R1)

(Verrillofungia
concinna) 		PF01353
(GFP) 		4 LEU A  58
VAL A 200
VAL A 207
LEU A  51
 None
 0.86A 4puoC-2zo7A:
undetectable		 4puoC-2zo7A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3alx HEMAGGLUTININ,LINKER
,CDW150

(Measles
morbillivirus;
Saguinus
oedipus;
synthetic
construct) 		PF00423
(HN)
PF06214
(SLAM) 		4 LEU A 205
VAL A 234
TYR A 214
TYR A 275
 None
 0.82A 4puoC-3alxA:
undetectable		 4puoC-3alxA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av6 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		4 LEU A 819
VAL A 837
TYR A 839
LEU A 898
 None
 1.03A 4puoC-3av6A:
undetectable		 4puoC-3av6A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT
MEMBRANE-BOUND
HYDROGENASE SMALL
SUBUNIT

(Hydrogenovibrio
marinus) 		PF00374
(NiFeSe_Hases)
PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		4 LEU A 211
VAL B  42
LEU B  54
TYR A 207
 None
 0.94A 4puoC-3ayxA:
undetectable		 4puoC-3ayxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3be5 PUTATIVE IRON
COMPOUND-BINDING
PROTEIN OF ABC
TRANSPORTER FAMILY

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		4 LEU A 111
VAL A  58
VAL A  61
LEU A 151
 None
 1.04A 4puoC-3be5A:
undetectable		 4puoC-3be5A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bhw UNCHARACTERIZED
PROTEIN

(Magnetospirillum
magneticum) 		PF08849
(DUF1819) 		4 LEU A 127
VAL A 152
LEU A  98
TYR A 126
 None
 0.96A 4puoC-3bhwA:
undetectable		 4puoC-3bhwA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c41 AMINO ACID ABC
TRANSPORTER (ARTP)

(Geobacillus
stearothermophilus) 		PF00005
(ABC_tran) 		4 LEU J 182
VAL J  82
VAL J 191
LEU J 151
 None
 0.99A 4puoC-3c41J:
undetectable		 4puoC-3c41J:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF00535
(Glycos_transf_2) 		4 VAL A 278
TYR A 234
LEU A 123
TYR A 218
 None
UDP  A 332 (-4.7A)
None
None
 0.84A 4puoC-3cknA:
undetectable		 4puoC-3cknA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cue TRANSPORT PROTEIN
PARTICLE 18 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF04099
(Sybindin) 		4 LEU C  86
VAL C 115
TYR C 123
TYR C 107
 None
 0.92A 4puoC-3cueC:
undetectable		 4puoC-3cueC:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3v REGULATORY PROTEIN
RECX

(Lactobacillus
salivarius) 		PF02631
(RecX) 		4 LEU A  67
VAL A  80
TYR A  63
LEU A 106
 None
 1.03A 4puoC-3e3vA:
undetectable		 4puoC-3e3vA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epf PROTEIN VP1

(Enterovirus C) 		PF00073
(Rhv) 		4 VAL 1 242
VAL 1 183
TYR 1 185
TYR 1 155
 None
 0.58A 4puoC-3epf1:
undetectable		 4puoC-3epf1:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ezo MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Burkholderia
pseudomallei) 		PF00698
(Acyl_transf_1) 		4 LEU A 110
VAL A 218
VAL A  97
LEU A 213
 None
 0.97A 4puoC-3ezoA:
undetectable		 4puoC-3ezoA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fhx PYRIDOXAL KINASE

(Homo sapiens) 		PF08543
(Phos_pyr_kin) 		4 LEU A   8
VAL A  94
LEU A  69
TYR A  77
 None
 0.99A 4puoC-3fhxA:
undetectable		 4puoC-3fhxA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fii BOTULINUM NEUROTOXIN
TYPE F

(Clostridium
botulinum) 		PF01742
(Peptidase_M27) 		4 LEU A 290
VAL A 336
TYR A 324
LEU A 348
 None
 0.76A 4puoC-3fiiA:
undetectable		 4puoC-3fiiA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftj MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN MACB

(Aggregatibacter
actinomycetemcomitans) 		PF12704
(MacB_PCD) 		4 VAL A 412
VAL A 468
TYR A 380
TYR A 462
 None
 1.00A 4puoC-3ftjA:
3.5		 4puoC-3ftjA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g9k CAPSULE BIOSYNTHESIS
PROTEIN CAPD

(Bacillus
anthracis) 		no annotation 5 LEU L 273
VAL L 261
VAL L 328
TYR L 256
LEU S 441
 None
 1.38A 4puoC-3g9kL:
undetectable		 4puoC-3g9kL:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gwj ARYLPHORIN

(Antheraea
pernyi) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 LEU A 575
VAL A 143
VAL A  15
LEU A 567
 None
 0.96A 4puoC-3gwjA:
undetectable		 4puoC-3gwjA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1l CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL
MITOCHONDRIAL
UBIQUINOL-CYTOCHROME
-C REDUCTASE COMPLEX
CORE PROTEIN 2

(Gallus gallus) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF09165
(Ubiq-Cytc-red_N) 		4 VAL B 314
VAL B 258
TYR B 325
LEU I  64
 None
 0.90A 4puoC-3h1lB:
4.1		 4puoC-3h1lB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i9v NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 3

(Thermus
thermophilus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4)
PF10588
(NADH-G_4Fe-4S_3)
PF13510
(Fer2_4) 		4 LEU 3 728
VAL 3 736
VAL 3 777
LEU 3 758
 None
 0.97A 4puoC-3i9v3:
undetectable		 4puoC-3i9v3:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ig3 PLXNA3 PROTEIN

(Mus musculus) 		PF08337
(Plexin_cytopl) 		4 LEU A1373
VAL A1824
LEU A1344
TYR A1379
 None
 0.97A 4puoC-3ig3A:
undetectable		 4puoC-3ig3A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyj MAJOR CAPSID PROTEIN
L1

(Deltapapillomavirus
4) 		no annotation 4 LEU F 328
VAL F  98
TYR F 308
LEU F 153
 None
 1.04A 4puoC-3iyjF:
undetectable		 4puoC-3iyjF:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C) 		PF06016
(Reovirus_L2) 		4 LEU W1250
VAL W1271
VAL W1237
TYR W1287
 None
 0.98A 4puoC-3iylW:
undetectable		 4puoC-3iylW:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jzj ACARBOSE/MALTOSE
BINDING PROTEIN GACH

(Streptomyces
glaucescens) 		PF13416
(SBP_bac_8) 		4 VAL A  52
VAL A  79
TYR A  54
TYR A 310
 None
 0.99A 4puoC-3jzjA:
undetectable		 4puoC-3jzjA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3knb OBSCURIN-LIKE
PROTEIN 1

(Homo sapiens) 		PF07679
(I-set) 		4 LEU B  73
VAL B  23
VAL B 103
LEU B  71
 None
 0.77A 4puoC-3knbB:
undetectable		 4puoC-3knbB:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l15 TRANSCRIPTIONAL
ENHANCER FACTOR
TEF-4

(Homo sapiens) 		no annotation 5 VAL A 252
VAL A 329
TYR A 327
TRP A 308
LEU A 306
 None
 1.36A 4puoC-3l15A:
undetectable		 4puoC-3l15A:
17.49