SIMILAR PATTERNS OF AMINO ACIDS FOR 4PST_A_FOLA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5f PROTEIN (CARDOSIN A)
PROTEIN (CARDOSIN A)

(Cynara
cardunculus;
Cynara
cardunculus) 		PF00026
(Asp)
PF00026
(Asp) 		3 ILE A  30
ASP B 303
ARG A 115
 None
 0.62A 4pstA-1b5fA:
undetectable		 4pstA-1b5fA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyg CYCLODEXTRIN
GLUCANOTRANSFERASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		3 ILE A 303
ASP A 278
ARG A 419
 None
 0.62A 4pstA-1cygA:
undetectable		 4pstA-1cygA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1euf DUODENASE

(Bos taurus) 		PF00089
(Trypsin) 		3 ILE A  17
ASP A 226
ARG A 187
 None
 0.84A 4pstA-1eufA:
undetectable		 4pstA-1eufA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kr1 HEVAMINE A

(Hevea
brasiliensis) 		PF00704
(Glyco_hydro_18) 		3 ILE A  64
ASP A 120
ARG A 112
 None
 0.80A 4pstA-1kr1A:
undetectable		 4pstA-1kr1A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1otw COENZYME PQQ
SYNTHESIS PROTEIN C

(Klebsiella
pneumoniae) 		PF03070
(TENA_THI-4) 		3 ILE A  57
ASP A 186
ARG A  50
 PQQ  A 500 ( 4.1A)
None
PQQ  A 500 (-2.5A)
 0.79A 4pstA-1otwA:
undetectable		 4pstA-1otwA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgu ACTIN INTERACTING
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		3 ILE A 231
ASP A 228
ARG A 277
 None
 0.83A 4pstA-1pguA:
undetectable		 4pstA-1pguA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tez DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE

(Synechococcus
elongatus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 ILE A  41
ASP A  46
ARG A  11
 HDF  A5486 (-3.9A)
None
HDF  A5486 ( 4.9A)
 0.81A 4pstA-1tezA:
undetectable		 4pstA-1tezA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tuo PUTATIVE
PHOSPHOMANNOMUTASE

(Thermus
thermophilus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ILE A 225
ASP A 387
ARG A 254
 None
 0.76A 4pstA-1tuoA:
undetectable		 4pstA-1tuoA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1k VANILLYL-ALCOHOL
OXIDASE

(Penicillium
simplicissimum) 		PF01565
(FAD_binding_4)
PF02913
(FAD-oxidase_C) 		3 ILE A 468
ASP A 170
ARG A 504
 EUG  A1562 (-4.0A)
FAD  A1561 ( 3.6A)
FAD  A1561 ( 3.4A)
 0.80A 4pstA-1w1kA:
undetectable		 4pstA-1w1kA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1whz HYPOTHETICAL PROTEIN

(Thermus
thermophilus) 		PF07927
(HicA_toxin) 		3 ILE A  38
ASP A  35
ARG A  22
 None
 0.67A 4pstA-1whzA:
undetectable		 4pstA-1whzA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		3 ILE A 297
ASP A 290
ARG A 401
 None
 0.80A 4pstA-1xfdA:
undetectable		 4pstA-1xfdA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7d ORNITHINE
AMINOTRANSFERASE

(Plasmodium
yoelii) 		PF00202
(Aminotran_3) 		3 ILE A 132
ASP A 190
ARG A 123
 None
 0.67A 4pstA-1z7dA:
undetectable		 4pstA-1z7dA:
15.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zdr DIHYDROFOLATE
REDUCTASE

(Geobacillus
stearothermophilus) 		PF00186
(DHFR_1) 		3 ILE A   5
ASP A  27
ARG A  57
 None
None
SO4  A3484 (-3.3A)
 0.45A 4pstA-1zdrA:
undetectable		 4pstA-1zdrA:
40.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a00 POTASSIUM-TRANSPORTI
NG ATPASE B CHAIN

(Escherichia
coli) 		no annotation 3 ILE A 393
ASP A 335
ARG A 438
 None
 0.73A 4pstA-2a00A:
undetectable		 4pstA-2a00A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b8n GLYCERATE KINASE,
PUTATIVE

(Thermotoga
maritima) 		PF05161
(MOFRL)
PF13660
(DUF4147) 		3 ILE A 335
ASP A 378
ARG A 281
 None
 0.60A 4pstA-2b8nA:
undetectable		 4pstA-2b8nA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi3 PHOSPHOSERINE
AMINOTRANSFERASE

(Bacillus
alcalophilus) 		PF00266
(Aminotran_5) 		3 ILE A 177
ASP A 172
ARG A 180
 None
PLP  A1361 (-2.9A)
None
 0.77A 4pstA-2bi3A:
undetectable		 4pstA-2bi3A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2blb DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
vivax) 		PF00186
(DHFR_1) 		3 ILE A  13
ASP A  53
ARG A 131
 CP7  A1240 (-4.1A)
CP7  A1240 (-3.1A)
MES  A1241 (-2.7A)
 0.28A 4pstA-2blbA:
undetectable		 4pstA-2blbA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfo GLUTAMYL-TRNA
SYNTHETASE

(Synechococcus
elongatus) 		PF00749
(tRNA-synt_1c) 		3 ILE A 209
ASP A 159
ARG A  21
 None
 0.84A 4pstA-2cfoA:
undetectable		 4pstA-2cfoA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvo PUTATIVE
SEMIALDEHYDE
DEHYDROGENASE

(Oryza sativa) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		3 ILE A 154
ASP A 106
ARG A 188
 None
 0.79A 4pstA-2cvoA:
undetectable		 4pstA-2cvoA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dt8 DEGV FAMILY PROTEIN

(Thermus
thermophilus) 		PF02645
(DegV) 		3 ILE A 264
ASP A  39
ARG A 170
 PLM  A 701 ( 4.5A)
None
PLM  A 701 (-4.1A)
 0.83A 4pstA-2dt8A:
undetectable		 4pstA-2dt8A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fbo VARIABLE
REGION-CONTAINING
CHITIN-BINDING
PROTEIN 3

(Branchiostoma
floridae) 		PF07686
(V-set) 		3 ILE J 116
ASP J  33
ARG J 229
 None
 0.84A 4pstA-2fboJ:
undetectable		 4pstA-2fboJ:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN

(Mycobacterium
tuberculosis) 		PF00994
(MoCF_biosynth) 		3 ILE A  28
ASP A  22
ARG A 136
 None
 0.83A 4pstA-2g4rA:
undetectable		 4pstA-2g4rA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g7z CONSERVED
HYPOTHETICAL PROTEIN
SPY1493

(Streptococcus
pyogenes) 		PF02645
(DegV) 		3 ILE A 263
ASP A  40
ARG A 172
 HXA  A9136 (-4.2A)
None
TRS  A5081 ( 3.6A)
 0.75A 4pstA-2g7zA:
undetectable		 4pstA-2g7zA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gsj PROTEIN PPL-2

(Parkia
platycephala) 		PF00704
(Glyco_hydro_18) 		3 ILE A  64
ASP A 120
ARG A 112
 None
 0.81A 4pstA-2gsjA:
undetectable		 4pstA-2gsjA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxv DIAMINOHYDROXYPHOSPH
ORIBOSYLAMINOPYRIMID
INE DEAMINASE/
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE

(Thermotoga
maritima) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		3 ILE A 266
ASP A 260
ARG A 273
 None
 0.79A 4pstA-2hxvA:
undetectable		 4pstA-2hxvA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inp PHENOL HYDROXYLASE
COMPONENT PHL

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox) 		3 ILE C 163
ASP C 223
ARG C  88
 None
 0.70A 4pstA-2inpC:
undetectable		 4pstA-2inpC:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2is8 MOLYBDOPTERIN
BIOSYNTHESIS ENZYME,
MOAB

(Thermus
thermophilus) 		PF00994
(MoCF_biosynth) 		3 ILE A  26
ASP A  20
ARG A 136
 None
FMT  A1003 (-3.7A)
None
 0.84A 4pstA-2is8A:
undetectable		 4pstA-2is8A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3w ZGC 92866

(Danio rerio) 		PF04051
(TRAPP) 		3 ILE B  85
ASP B 182
ARG B  78
 None
 0.82A 4pstA-2j3wB:
undetectable		 4pstA-2j3wB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5x N-ACETYLSEROTONIN
O-METHYLTRANSFERASE-
LIKE PROTEIN

(Homo sapiens) 		PF02545
(Maf) 		3 ILE A  27
ASP A 192
ARG A  23
 None
 0.79A 4pstA-2p5xA:
undetectable		 4pstA-2p5xA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qty POLY(ADP-RIBOSE)
GLYCOHYDROLASE ARH3

(Mus musculus) 		PF03747
(ADP_ribosyl_GH) 		3 ILE A   4
ASP A 334
ARG A 342
 None
 0.84A 4pstA-2qtyA:
undetectable		 4pstA-2qtyA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa) 		PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc) 		3 ILE A 880
ASP A1033
ARG A 999
 None
 0.84A 4pstA-2vz9A:
undetectable		 4pstA-2vz9A:
5.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2w9s DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003

(Staphylococcus
aureus) 		PF00186
(DHFR_1) 		3 ILE A   5
ASP A  27
ARG A  57
 TOP  A1160 (-4.2A)
TOP  A1160 (-2.8A)
None
 0.43A 4pstA-2w9sA:
undetectable		 4pstA-2w9sA:
38.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyl 4-HYDROXYPHENYLACETA
TE-3-HYDROXYLASE

(Thermus
thermophilus) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 ILE A   9
ASP A  28
ARG A  40
 None
 0.59A 4pstA-2yylA:
undetectable		 4pstA-2yylA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zdj HYPOTHETICAL PROTEIN
TTMA177

(unidentified) 		no annotation 3 ILE A  30
ASP A  47
ARG A  67
 None
 0.70A 4pstA-2zdjA:
undetectable		 4pstA-2zdjA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1n NDP-SUGAR EPIMERASE

(Thermoplasma
volcanium) 		PF01370
(Epimerase) 		3 ILE A 250
ASP A 299
ARG A 192
 None
 0.77A 4pstA-3a1nA:
undetectable		 4pstA-3a1nA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ada SARCOSINE OXIDASE
BETA SUBUNIT

(Corynebacterium
sp. U-96) 		PF01266
(DAO) 		3 ILE B 268
ASP B 115
ARG B 155
 None
 0.67A 4pstA-3adaB:
undetectable		 4pstA-3adaB:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Thermotoga
maritima) 		PF01425
(Amidase) 		3 ILE A 413
ASP A 161
ARG A 367
 None
 0.55A 4pstA-3al0A:
undetectable		 4pstA-3al0A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al0 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT
C,LINKER,GLUTAMATE--
TRNA LIGASE 2

(Thermotoga
maritima;
Thermotoga
maritima;
synthetic
construct) 		PF01425
(Amidase)
PF00749
(tRNA-synt_1c)
PF02686
(Glu-tRNAGln) 		3 ILE C  35
ASP A 401
ARG A 343
 None
 0.78A 4pstA-3al0C:
undetectable		 4pstA-3al0C:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asm RIBONUCLEASE HIII

(Geobacillus
stearothermophilus) 		PF01351
(RNase_HII)
PF11858
(DUF3378) 		3 ILE A 221
ASP A 189
ARG A 224
 None
 0.84A 4pstA-3asmA:
undetectable		 4pstA-3asmA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bmw CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		3 ILE A 308
ASP A 283
ARG A 423
 None
 0.63A 4pstA-3bmwA:
undetectable		 4pstA-3bmwA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwx ALPHA/BETA HYDROLASE

(Novosphingobium
aromaticivorans) 		PF12697
(Abhydrolase_6) 		3 ILE A 141
ASP A 238
ARG A  39
 None
 0.71A 4pstA-3bwxA:
undetectable		 4pstA-3bwxA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6r NON-STRUCTURAL
PROTEIN 1

(Influenza A
virus) 		no annotation 3 ILE B 123
ASP B 153
ARG B 220
 None
 0.70A 4pstA-3d6rB:
undetectable		 4pstA-3d6rB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dg8 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00186
(DHFR_1) 		3 ILE A  14
ASP A  54
ARG A 122
 RJ6  A 609 (-4.5A)
RJ6  A 609 (-3.0A)
None
 0.23A 4pstA-3dg8A:
undetectable		 4pstA-3dg8A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 ILE B 157
ASP B  39
ARG B  86
 None
 0.84A 4pstA-3h0gB:
undetectable		 4pstA-3h0gB:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7n NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae) 		PF11715
(Nup160) 		3 ILE A 397
ASP A 394
ARG A 628
 None
 0.79A 4pstA-3h7nA:
undetectable		 4pstA-3h7nA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h96 F420-H2 DEPENDENT
REDUCTASE A

(Mycolicibacterium
smegmatis) 		PF04075
(F420H2_quin_red) 		3 ILE A 110
ASP A  56
ARG A 117
 None
 0.79A 4pstA-3h96A:
undetectable		 4pstA-3h96A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hut PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC TRANSPORTER

(Rhodospirillum
rubrum) 		PF13458
(Peripla_BP_6) 		3 ILE A 384
ASP A 173
ARG A 377
 None
 0.69A 4pstA-3hutA:
undetectable		 4pstA-3hutA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb4 VP0

(Parechovirus B) 		PF00073
(Rhv) 		3 ILE B 256
ASP B 209
ARG B 248
 None
 0.62A 4pstA-3jb4B:
undetectable		 4pstA-3jb4B:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbl NLR FAMILY CARD
DOMAIN-CONTAINING
PROTEIN 4

(Mus musculus) 		no annotation 3 ILE K 669
ASP K 615
ARG K 619
 None
 0.72A 4pstA-3jblK:
undetectable		 4pstA-3jblK:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k96 GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD(P)+]

(Coxiella
burnetii) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		3 ILE A  79
ASP A 100
ARG A  32
 None
 0.84A 4pstA-3k96A:
undetectable		 4pstA-3k96A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg0 ORNITHINE
AMINOTRANSFERASE

(Plasmodium
falciparum) 		PF00202
(Aminotran_3) 		3 ILE A 133
ASP A 191
ARG A 124
 None
 0.75A 4pstA-3lg0A:
undetectable		 4pstA-3lg0A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3maj DNA PROCESSING CHAIN
A

(Rhodopseudomonas
palustris) 		PF02481
(DNA_processg_A) 		3 ILE A 302
ASP A 327
ARG A 261
 None
 0.83A 4pstA-3majA:
undetectable		 4pstA-3majA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qq8 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE

(Homo sapiens) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		3 ILE A  70
ASP A  35
ARG A  53
 None
 0.81A 4pstA-3qq8A:
undetectable		 4pstA-3qq8A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r1x 2-OXO-3-DEOXYGALACTO
NATE KINASE

(Klebsiella
pneumoniae) 		PF05035
(DGOK) 		3 ILE A   6
ASP A  56
ARG A  29
 None
 0.50A 4pstA-3r1xA:
undetectable		 4pstA-3r1xA:
19.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tq9 DIHYDROFOLATE
REDUCTASE

(Coxiella
burnetii) 		PF00186
(DHFR_1) 		3 ILE A   6
ASP A  28
ARG A  58
 MTX  A2001 (-4.0A)
MTX  A2001 (-2.7A)
MTX  A2001 (-2.8A)
 0.29A 4pstA-3tq9A:
undetectable		 4pstA-3tq9A:
43.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3um6 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 ILE A  14
ASP A  54
ARG A 122
 1CY  A 609 (-4.3A)
1CY  A 609 (-2.9A)
None
 0.25A 4pstA-3um6A:
undetectable		 4pstA-3um6A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a1f REPLICATIVE DNA
HELICASE

(Helicobacter
pylori) 		PF03796
(DnaB_C) 		3 ILE A 334
ASP A 374
ARG A 289
 None
 0.64A 4pstA-4a1fA:
undetectable		 4pstA-4a1fA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ain GLYCINE BETAINE
TRANSPORTER BETP

(Corynebacterium
glutamicum) 		PF02028
(BCCT) 		3 ILE A 204
ASP A 239
ARG A 387
 None
 0.69A 4pstA-4ainA:
undetectable		 4pstA-4ainA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3i FATTY ACID
BETA-OXIDATION
COMPLEX ALPHA-CHAIN
FADB

(Mycobacterium
tuberculosis) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		3 ILE A  52
ASP A  11
ARG A  44
 None
 0.83A 4pstA-4b3iA:
undetectable		 4pstA-4b3iA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgt CYCLODEXTRIN
GLYCOSYLTRANSFERASE

(Bacillus
circulans) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		3 ILE A 307
ASP A 282
ARG A 423
 None
 0.66A 4pstA-4cgtA:
undetectable		 4pstA-4cgtA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft6 PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		3 ILE A 380
ASP A 344
ARG A 124
 None
 0.78A 4pstA-4ft6A:
undetectable		 4pstA-4ft6A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6z GLUTAMATE-TRNA
LIGASE

(Burkholderia
thailandensis) 		PF00749
(tRNA-synt_1c) 		3 ILE A 204
ASP A 160
ARG A  23
 None
 0.84A 4pstA-4g6zA:
undetectable		 4pstA-4g6zA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7k CATION EFFLUX SYSTEM
PROTEIN CUSC

(Escherichia
coli) 		PF02321
(OEP) 		3 ILE A 353
ASP A 265
ARG A 284
 None
 0.72A 4pstA-4k7kA:
undetectable		 4pstA-4k7kA:
17.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m2x DIHYDROFOLATE
REDUCTASE

(Mycobacterium
tuberculosis) 		PF00186
(DHFR_1) 		3 ILE A   5
ASP A  27
ARG A  60
 TMQ  A 202 (-4.0A)
TMQ  A 202 ( 2.7A)
None
 0.33A 4pstA-4m2xA:
undetectable		 4pstA-4m2xA:
35.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4m7v DIHYDROFOLATE
REDUCTASE

(Enterococcus
faecalis) 		PF00186
(DHFR_1) 		3 ILE A   5
ASP A  27
ARG A  58
 RAR  A 200 (-4.0A)
RAR  A 200 (-2.6A)
RAR  A 200 ( 3.2A)
 0.56A 4pstA-4m7vA:
undetectable		 4pstA-4m7vA:
37.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ns4 ALPHA/BETA HYDROLASE
FOLD PROTEIN

(Psychrobacter
cryohalolentis) 		PF00561
(Abhydrolase_1) 		3 ILE A 121
ASP A 214
ARG A  96
 None
 0.67A 4pstA-4ns4A:
undetectable		 4pstA-4ns4A:
19.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4p68 DIHYDROFOLATE
REDUCTASE

(Escherichia
coli) 		PF00186
(DHFR_1) 		3 ILE A   5
ASP A  27
ARG A  57
 MTX  A 201 (-4.1A)
MTX  A 201 (-3.0A)
MTX  A 201 (-3.0A)
 0.24A 4pstA-4p68A:
undetectable		 4pstA-4p68A:
98.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ras OXIDOREDUCTASE,
NAD-BINDING/IRON-SUL
FUR CLUSTER-BINDING
PROTEIN

(Nitratireductor
pacificus) 		PF12838
(Fer4_7)
PF13486
(Dehalogenase) 		3 ILE A 432
ASP A 366
ARG A 144
 None
 0.83A 4pstA-4rasA:
undetectable		 4pstA-4rasA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4toq CLASS III CHITINASE

(Punica granatum) 		PF00704
(Glyco_hydro_18) 		3 ILE A  64
ASP A 120
ARG A 112
 None
 0.76A 4pstA-4toqA:
undetectable		 4pstA-4toqA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uir OLEATE HYDRATASE

(Elizabethkingia
meningoseptica) 		PF06100
(MCRA) 		3 ILE A  72
ASP A 101
ARG A 121
 FAD  A 701 (-4.8A)
None
FAD  A 701 (-4.1A)
 0.84A 4pstA-4uirA:
undetectable		 4pstA-4uirA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcj POLYSACCHARIDE
DEACETYLASE

(Ammonifex
degensii) 		PF01522
(Polysacc_deac_1) 		3 ILE A 140
ASP A 201
ARG A 146
 None
 0.71A 4pstA-4wcjA:
undetectable		 4pstA-4wcjA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa) 		PF01425
(Amidase) 		3 ILE A 427
ASP A 172
ARG A 380
 None
 0.52A 4pstA-4wj3A:
undetectable		 4pstA-4wj3A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9x DEGV
DOMAIN-CONTAINING
PROTEIN MW1315

(Staphylococcus
aureus) 		PF02645
(DegV) 		3 ILE A 118
ASP A   9
ARG A 170
 OLA  A 301 (-3.7A)
None
OLA  A 301 (-3.3A)
 0.79A 4pstA-4x9xA:
undetectable		 4pstA-4x9xA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhj ENVELOPE
GLYCOPROTEIN H

(Human
alphaherpesvirus
3) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		3 ILE A 743
ASP A 582
ARG A 733
 None
 0.72A 4pstA-4xhjA:
undetectable		 4pstA-4xhjA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z6k ALCOHOL
DEHYDROGENASE

(Moraxella sp.
TAE123) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 ILE A 133
ASP A 297
ARG A  82
 None
 0.81A 4pstA-4z6kA:
undetectable		 4pstA-4z6kA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9c PERTUSSIS TOXIN-LIKE
SUBUNIT ARTA

(Escherichia
coli) 		PF02917
(Pertussis_S1) 		3 ILE A  18
ASP A 201
ARG A   9
 None
 0.62A 4pstA-4z9cA:
undetectable		 4pstA-4z9cA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aar POTASSIUM CHANNEL
AKT1

(Arabidopsis
thaliana) 		PF12796
(Ank_2) 		3 ILE A 557
ASP A 548
ARG A 528
 None
 0.73A 4pstA-5aarA:
undetectable		 4pstA-5aarA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7i CRISPR-ASSOCIATED
NUCLEASE/HELICASE
CAS3 SUBTYPE
I-F/YPEST

(Pseudomonas
aeruginosa) 		no annotation 3 ILE A 730
ASP A 833
ARG A 799
 None
 0.80A 4pstA-5b7iA:
undetectable		 4pstA-5b7iA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpt MGC81278 PROTEIN

(Xenopus laevis) 		PF12894
(ANAPC4_WD40)
PF12896
(ANAPC4) 		3 ILE A 613
ASP A 657
ARG A 582
 None
 0.80A 4pstA-5bptA:
undetectable		 4pstA-5bptA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5by7 3-OXOACYL-ACP
SYNTHASE III

(Verrucosispora
maris) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		3 ILE A  39
ASP A  45
ARG A 136
 None
 0.78A 4pstA-5by7A:
undetectable		 4pstA-5by7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czc MALONYL-COA-[ACYL-CA
RRIER-PROTEIN]
TRANSACYLASE

(Streptomyces
halstedii) 		no annotation 3 ILE A  78
ASP A  54
ARG A 133
 None
 0.78A 4pstA-5czcA:
undetectable		 4pstA-5czcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS

(Bacillus
halmapalus) 		PF00082
(Peptidase_S8)
PF04151
(PPC) 		3 ILE A   7
ASP A  11
ARG A 188
 None
None
5VV  A   1 ( 3.6A)
 0.83A 4pstA-5fbzA:
undetectable		 4pstA-5fbzA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4e BETA 1-3 GLUCANASE

(Clostridium
beijerinckii) 		no annotation 3 ILE A 325
ASP A 347
ARG A 314
 None
 0.83A 4pstA-5h4eA:
undetectable		 4pstA-5h4eA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ife PHD FINGER-LIKE
DOMAIN-CONTAINING
PROTEIN 5A

(Homo sapiens) 		PF03660
(PHF5) 		3 ILE D  88
ASP D  34
ARG D  12
 None
 0.70A 4pstA-5ifeD:
undetectable		 4pstA-5ifeD:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk0 TYROSINE RECOMBINASE
XERH

(Helicobacter
pylori) 		PF00589
(Phage_integrase) 		3 ILE A 204
ASP A 188
ARG A 294
 None
 0.79A 4pstA-5jk0A:
undetectable		 4pstA-5jk0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mjv CAPSID SUBUNIT VP0

(Parechovirus A) 		PF00073
(Rhv) 		3 ILE C 286
ASP C 239
ARG C 278
 None
 0.74A 4pstA-5mjvC:
undetectable		 4pstA-5mjvC:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2s DARPIN K27

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2) 		3 ILE B 162
ASP B 153
ARG B 133
 None
 0.55A 4pstA-5o2sB:
undetectable		 4pstA-5o2sB:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocr KAPPA-CARRAGEENASE

(Zobellia
galactanivorans) 		no annotation 3 ILE A 292
ASP A 131
ARG A  94
 None
 0.83A 4pstA-5ocrA:
undetectable		 4pstA-5ocrA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj3 ALKALINE PHOSPHATASE
PAFA

(Elizabethkingia
meningoseptica) 		PF01663
(Phosphodiest) 		3 ILE A 470
ASP A 473
ARG A 454
 None
 0.83A 4pstA-5tj3A:
undetectable		 4pstA-5tj3A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u22 N2152

(Neocallimastix
frontalis) 		PF01229
(Glyco_hydro_39) 		3 ILE A 109
ASP A 183
ARG A  80
 None
 0.63A 4pstA-5u22A:
undetectable		 4pstA-5u22A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wyp DNA POLYMERASE III
SUBUNIT BETA

(Caulobacter
vibrioides) 		no annotation 3 ILE A  53
ASP A  48
ARG A 211
 None
 0.74A 4pstA-5wypA:
undetectable		 4pstA-5wypA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxu RIBOSOMAL PROTEIN
ES6

(Toxoplasma
gondii) 		PF01092
(Ribosomal_S6e) 		3 ILE G 173
ASP G 152
ARG G 159
 A  2  77 ( 4.5A)
None
U  2  76 ( 3.4A)
 0.82A 4pstA-5xxuG:
undetectable		 4pstA-5xxuG:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zya PHD FINGER-LIKE
DOMAIN-CONTAINING
PROTEIN 5A

(Homo sapiens) 		no annotation 3 ILE D  88
ASP D  34
ARG D  12
 None
 0.69A 4pstA-5zyaD:
undetectable		 4pstA-5zyaD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ay1 NUCLEOSIDE
DIPHOSPHATE KINASE

(Helicobacter
pylori) 		PF00334
(NDK) 		3 ILE A   9
ASP A  12
ARG A  38
 None
 0.81A 4pstA-6ay1A:
undetectable		 4pstA-6ay1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b1z GLUTAMATE--TRNA
LIGASE

(Elizabethkingia
anophelis) 		PF00749
(tRNA-synt_1c) 		3 ILE A 219
ASP A 175
ARG A  22
 None
None
EDO  A 617 ( 3.7A)
 0.77A 4pstA-6b1zA:
undetectable		 4pstA-6b1zA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btm ALTERNATIVE COMPLEX
III SUBUNIT C

(Flavobacterium
johnsoniae) 		no annotation 3 ILE C  80
ASP C 164
ARG C 387
 None
 0.71A 4pstA-6btmC:
undetectable		 4pstA-6btmC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxm DIHYDROFOLATE
REDUCTASE

(Mycolicibacterium
smegmatis) 		no annotation 3 ILE A   6
ASP A  28
ARG A  61
 MMV  A 202 (-4.0A)
MMV  A 202 (-2.9A)
MMV  A 202 (-2.8A)
 0.36A 4pstA-6cxmA:
undetectable		 4pstA-6cxmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ewz GTP
PYROPHOSPHOKINASE

(Staphylococcus
aureus) 		no annotation 3 ILE A 121
ASP A 141
ARG A 178
 None
None
GTP  A 301 ( 4.7A)
 0.81A 4pstA-6ewzA:
undetectable		 4pstA-6ewzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k POLYSULPHIDE
REDUCTASE NRFD

(Rhodothermus
marinus) 		no annotation 3 ILE C  86
ASP C 169
ARG C 395
 None
 0.85A 4pstA-6f0kC:
undetectable		 4pstA-6f0kC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f2t -

(-) 		no annotation 3 ILE A 411
ASP A 457
ARG A 409
 None
 0.77A 4pstA-6f2tA:
undetectable		 4pstA-6f2tA:
undetectable