SIMILAR PATTERNS OF AMINO ACIDS FOR 4PO0_A_NPSA603

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ch4 MODULE-SUBSTITUTED
CHIMERA HEMOGLOBIN
BETA-ALPHA

(Homo sapiens) 		PF00042
(Globin) 		5 LEU A 114
LEU A  14
VAL A 133
LEU A   3
LEU A  78
 None
 1.20A 4po0A-1ch4A:
2.5		 4po0A-1ch4A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1coy CHOLESTEROL OXIDASE

(Brevibacterium
sterolicum) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		5 LEU A 233
LEU A 242
VAL A  40
LEU A   6
LEU A  15
 None
 1.19A 4po0A-1coyA:
undetectable		 4po0A-1coyA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e1t LYSYL-TRNA
SYNTHETASE, HEAT
INDUCIBLE

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		5 LEU A 152
LEU A 117
LEU A 142
LEU A  96
VAL A  98
 None
 1.16A 4po0A-1e1tA:
undetectable		 4po0A-1e1tA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5t INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE

(Thermotoga
maritima) 		PF00218
(IGPS) 		5 LEU A 107
LEU A 133
LEU A 142
LEU A 174
VAL A 178
 None
 1.20A 4po0A-1j5tA:
undetectable		 4po0A-1j5tA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		5 LEU A1133
LEU A1129
VAL A1160
LEU A1165
LEU A1168
 None
 1.13A 4po0A-1jl5A:
1.7		 4po0A-1jl5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		5 LEU A1312
LEU A1315
VAL A1352
LEU A1355
LEU A1362
 None
 1.11A 4po0A-1jl5A:
1.7		 4po0A-1jl5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		5 LEU A1329
LEU A1312
VAL A1284
LEU A1282
LEU A1272
 None
 1.18A 4po0A-1jl5A:
1.7		 4po0A-1jl5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmv UNIVERSAL STRESS
PROTEIN A

(Haemophilus
influenzae) 		PF00582
(Usp) 		5 LEU A  94
LEU A   6
LEU A  19
LEU A  72
VAL A  76
 None
 0.94A 4po0A-1jmvA:
undetectable		 4po0A-1jmvA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knr L-ASPARTATE OXIDASE

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		5 LEU A 370
LEU A 202
VAL A 235
LEU A 238
LEU A 499
 None
 1.13A 4po0A-1knrA:
2.4		 4po0A-1knrA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1luj CATENIN BETA-1

(Homo sapiens) 		PF00514
(Arm) 		5 ASN A 431
ASN A 434
VAL A 438
LEU A 402
LEU A 424
 None
 1.16A 4po0A-1lujA:
2.2		 4po0A-1lujA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A

(Haemophilus
influenzae) 		PF06026
(Rib_5-P_isom_A) 		5 ASN A 196
VAL A 144
LEU A 148
LEU A 170
VAL A 172
 None
 1.05A 4po0A-1m0sA:
undetectable		 4po0A-1m0sA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC

(Klebsiella
pneumoniae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		5 LEU A 328
LEU A 230
VAL A 301
LEU A 277
LEU A 203
 None
 1.07A 4po0A-1ozhA:
undetectable		 4po0A-1ozhA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozn RETICULON 4 RECEPTOR

(Homo sapiens) 		PF13855
(LRR_8) 		5 LEU A 166
ASN A 164
VAL A 121
LEU A 118
LEU A 112
 None
 1.18A 4po0A-1oznA:
undetectable		 4po0A-1oznA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qm9 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN

(Homo sapiens) 		PF00076
(RRM_1)
PF13893
(RRM_5) 		5 LEU A  66
VAL A   8
LEU A  11
LEU A  21
VAL A  16
 None
 1.18A 4po0A-1qm9A:
undetectable		 4po0A-1qm9A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rwr FILAMENTOUS
HEMAGGLUTININ

(Bordetella
pertussis) 		PF05860
(Haemagg_act) 		5 LEU A 122
LEU A 101
VAL A  41
LEU A   3
VAL A  11
 None
 0.93A 4po0A-1rwrA:
undetectable		 4po0A-1rwrA:
18.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 ASN A 405
VAL A 409
LEU A 529
LEU A 544
LYS A 545
 None
 0.79A 4po0A-1tf0A:
46.3		 4po0A-1tf0A:
74.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 LEU A 394
LEU A 398
ASN A 405
VAL A 409
LEU A 529
 None
 0.39A 4po0A-1tf0A:
46.3		 4po0A-1tf0A:
74.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 LEU A 394
LEU A 398
VAL A 409
LEU A 529
VAL A 547
 None
 1.20A 4po0A-1tf0A:
46.3		 4po0A-1tf0A:
74.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 LEU A 398
ASN A 405
VAL A 409
LEU A 529
LEU A 544
 None
 0.58A 4po0A-1tf0A:
46.3		 4po0A-1tf0A:
74.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vd6 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Thermus
thermophilus) 		PF03009
(GDPD) 		5 LEU A 145
ASN A  98
VAL A  96
LEU A  11
LEU A   9
 None
 1.19A 4po0A-1vd6A:
undetectable		 4po0A-1vd6A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		5 LEU A 338
VAL A 324
LEU A 374
LEU A 321
VAL A 378
 None
 1.21A 4po0A-1w99A:
3.7		 4po0A-1w99A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yrg GTPASE-ACTIVATING
PROTEIN RNA1_SCHPO

(Schizosaccharomyces
pombe) 		no annotation 5 LEU A 146
LEU A 149
VAL A  99
LEU A  96
LEU A  90
 None
 1.04A 4po0A-1yrgA:
undetectable		 4po0A-1yrgA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7z INTERCELLULAR
ADHESION MOLECULE-1

(Homo sapiens) 		PF03921
(ICAM_N) 		5 ASN I  56
VAL I  17
LEU I  11
LEU I  80
VAL I  82
 None
 1.13A 4po0A-1z7zI:
undetectable		 4po0A-1z7zI:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4w GLYCEROL KINASE

(Cellulomonas
sp.) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		5 LEU A 287
ASN A 398
LEU A 428
LEU A 408
VAL A 430
 None
 1.16A 4po0A-2d4wA:
undetectable		 4po0A-2d4wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv2 RCD1 REQUIRED FOR
CELL
DIFFERENTIATION1
HOMOLOG

(Homo sapiens) 		PF04078
(Rcd1) 		5 LEU A 233
LEU A 237
VAL A 216
LEU A 213
LEU A 204
 None
 1.21A 4po0A-2fv2A:
2.6		 4po0A-2fv2A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2htm THIAZOLE
BIOSYNTHESIS PROTEIN
THIG

(Thermus
thermophilus) 		PF05690
(ThiG) 		5 LEU A 205
VAL A  42
LEU A  61
LEU A  66
VAL A  64
 None
 1.21A 4po0A-2htmA:
undetectable		 4po0A-2htmA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k19 PUTATIVE PISCICOLIN
126 IMMUNITY PROTEIN

(Carnobacterium
maltaromaticum) 		PF08951
(EntA_Immun) 		5 LEU A  88
LEU A  85
VAL A  40
LEU A  37
VAL A  75
 None
 1.13A 4po0A-2k19A:
2.4		 4po0A-2k19A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oce HYPOTHETICAL PROTEIN
PA5201

(Pseudomonas
aeruginosa) 		PF00575
(S1)
PF09371
(Tex_N)
PF12836
(HHH_3)
PF16921
(Tex_YqgF) 		5 LEU A 401
VAL A 344
LEU A 332
LEU A 378
VAL A 384
 None
 1.05A 4po0A-2oceA:
undetectable		 4po0A-2oceA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2odh R.BCNI

(Brevibacillus
centrosporus) 		PF15515
(MvaI_BcnI) 		5 LEU A 227
LEU A 182
VAL A 159
LEU A  13
VAL A   9
 PEG  A 240 ( 4.8A)
None
None
None
None
 1.20A 4po0A-2odhA:
undetectable		 4po0A-2odhA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5s RAS AND EF-HAND
DOMAIN CONTAINING

(Homo sapiens) 		PF00071
(Ras) 		5 LEU A 558
LEU A 594
VAL A 698
LEU A 702
VAL A 585
 None
 1.17A 4po0A-2p5sA:
undetectable		 4po0A-2p5sA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcq PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE

(Thermus
thermophilus) 		PF00701
(DHDPS) 		5 LEU A 229
LEU A 233
ASN A 198
LEU A  28
LEU A 250
 None
 1.09A 4po0A-2pcqA:
undetectable		 4po0A-2pcqA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qen WALKER-TYPE ATPASE

(Pyrococcus
abyssi) 		PF01637
(ATPase_2) 		5 LEU A 140
LEU A 151
VAL A 132
LEU A 165
LEU A 120
 None
 0.84A 4po0A-2qenA:
undetectable		 4po0A-2qenA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsv UNCHARACTERIZED
PROTEIN

(Porphyromonas
gingivalis) 		PF07610
(DUF1573) 		5 LEU A  65
LEU A  82
VAL A  27
LEU A   3
VAL A  86
 None
 1.07A 4po0A-2qsvA:
undetectable		 4po0A-2qsvA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r98 PUTATIVE
ACETYLGLUTAMATE
SYNTHASE

(Neisseria
gonorrhoeae) 		PF00583
(Acetyltransf_1)
PF00696
(AA_kinase) 		5 LEU A  34
LEU A  43
VAL A 203
LEU A  26
LEU A 271
 None
 1.15A 4po0A-2r98A:
undetectable		 4po0A-2r98A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7y CHAPERONE PROTEIN
DNAK

(Geobacillus
kaustophilus) 		PF00012
(HSP70) 		5 LEU A 196
LEU A 168
VAL A 289
LEU A 164
LEU A 326
 None
 1.12A 4po0A-2v7yA:
2.5		 4po0A-2v7yA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7y CHAPERONE PROTEIN
DNAK

(Geobacillus
kaustophilus) 		PF00012
(HSP70) 		5 LEU A 196
LEU A 168
VAL A 289
LEU A 164
VAL A 306
 None
 1.18A 4po0A-2v7yA:
2.5		 4po0A-2v7yA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4g MYOSIN HEAVY CHAIN,
SKELETAL MUSCLE,
ADULT

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		6 LEU M 401
LEU M 397
VAL M 433
LEU M 619
LEU M 354
VAL M 616
 None
 1.45A 4po0A-2w4gM:
2.2		 4po0A-2w4gM:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2waw MOBA RELATE PROTEIN

(Mycobacterium
sp. DSM 3803) 		PF12804
(NTP_transf_3) 		5 LEU A  34
VAL A   9
LEU A 101
LEU A  85
VAL A 158
 None
 1.21A 4po0A-2wawA:
undetectable		 4po0A-2wawA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x40 BETA-GLUCOSIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		5 LEU A 304
ASN A 299
VAL A  20
LEU A 253
LEU A 293
 None
 1.19A 4po0A-2x40A:
undetectable		 4po0A-2x40A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xu0 ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding)
PF15447
(NTS) 		5 LEU A 162
ASN A 160
LEU A 146
LEU A 221
VAL A 224
 None
 1.21A 4po0A-2xu0A:
undetectable		 4po0A-2xu0A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus) 		PF00148
(Oxidored_nitro)
PF08369
(PCP_red) 		5 LEU D  90
LEU D  26
LEU D 215
LEU D 172
VAL D 201
 None
 1.04A 4po0A-2ynmD:
undetectable		 4po0A-2ynmD:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yrr AMINOTRANSFERASE,
CLASS V

(Thermus
thermophilus) 		PF00266
(Aminotran_5) 		5 LEU A 350
LEU A 346
VAL A 291
LEU A 289
LEU A 268
 None
 1.03A 4po0A-2yrrA:
undetectable		 4po0A-2yrrA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6h CATENIN BETA-1

(Homo sapiens) 		PF00514
(Arm) 		5 ASN A 431
ASN A 434
VAL A 438
LEU A 402
LEU A 424
 None
 1.18A 4po0A-2z6hA:
2.0		 4po0A-2z6hA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3agk PEPTIDE CHAIN
RELEASE FACTOR
SUBUNIT 1

(Aeropyrum
pernix) 		PF03464
(eRF1_2)
PF03465
(eRF1_3) 		5 LEU A 263
VAL A 222
LEU A 248
LEU A 240
VAL A 235
 None
 1.14A 4po0A-3agkA:
2.1		 4po0A-3agkA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo sapiens) 		PF04042
(DNA_pol_E_B) 		5 LEU A 283
VAL A 199
LEU A 197
LEU A 218
VAL A 222
 None
 1.19A 4po0A-3e0jA:
undetectable		 4po0A-3e0jA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fe1 HEAT SHOCK 70 KDA
PROTEIN 6

(Homo sapiens) 		PF00012
(HSP70) 		5 LEU A 230
LEU A 202
VAL A 319
LEU A 198
VAL A 336
 None
 1.18A 4po0A-3fe1A:
2.7		 4po0A-3fe1A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3get HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Campylobacter
jejuni) 		PF00155
(Aminotran_1_2) 		5 LEU A  69
LEU A  73
VAL A  93
LEU A 219
LEU A 221
 None
 1.20A 4po0A-3getA:
undetectable		 4po0A-3getA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go9 INSULINASE FAMILY
PROTEASE

(Yersinia pestis) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		5 LEU A 464
LEU A 348
ASN A 351
VAL A 355
LEU A 324
 None
 0.88A 4po0A-3go9A:
undetectable		 4po0A-3go9A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gon PHOSPHOMEVALONATE
KINASE

(Streptococcus
pneumoniae) 		PF00288
(GHMP_kinases_N) 		5 LEU A 179
VAL A 115
LEU A 119
LEU A 131
VAL A 126
 None
 1.18A 4po0A-3gonA:
3.5		 4po0A-3gonA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7r ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		6 LEU A 106
LEU A 108
ASN A 175
VAL A 197
LEU A 161
LEU A 165
 None
 1.32A 4po0A-3h7rA:
undetectable		 4po0A-3h7rA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7u ALDO-KETO REDUCTASE

(Arabidopsis
thaliana) 		PF00248
(Aldo_ket_red) 		6 LEU A 110
LEU A 112
ASN A 179
VAL A 201
LEU A 165
LEU A 169
 None
 1.35A 4po0A-3h7uA:
undetectable		 4po0A-3h7uA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kez PUTATIVE SUGAR
BINDING PROTEIN

(Bacteroides
vulgatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		5 LEU A 141
LEU A 204
ASN A 134
LEU A  41
LEU A 123
 None
 1.12A 4po0A-3kezA:
undetectable		 4po0A-3kezA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT C

(Thermus
thermophilus) 		PF02637
(GatB_Yqey)
PF02686
(Glu-tRNAGln)
PF02934
(GatB_N) 		5 LEU F  64
LEU F 280
VAL F  56
LEU G  57
LEU F  74
 None
 1.20A 4po0A-3kfuF:
2.1		 4po0A-3kfuF:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kg7 CURH

(Lyngbya
majuscula) 		PF14765
(PS-DH) 		5 LEU A1121
LEU A1125
LEU A1166
LEU A 989
VAL A 994
 None
 1.20A 4po0A-3kg7A:
undetectable		 4po0A-3kg7A:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ly9 TRANSCRIPTIONAL
ACTIVATOR CADC

(Escherichia
coli) 		no annotation 5 LEU A 330
LEU A 326
VAL A 227
LEU A 231
LEU A 310
 None
 1.15A 4po0A-3ly9A:
undetectable		 4po0A-3ly9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6x RRNA METHYLASE

(Thermus
thermophilus) 		PF01189
(Methyltr_RsmB-F)
PF17125
(Methyltr_RsmF_N)
PF17126
(RsmF_methylt_CI) 		5 LEU A 355
LEU A 218
ASN A 132
LEU A 108
VAL A 174
 None
 1.06A 4po0A-3m6xA:
undetectable		 4po0A-3m6xA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4g ANTIFREEZE PROTEIN

(Marinomonas
primoryensis) 		no annotation 5 LEU A 208
VAL A 240
LEU A 261
LEU A 254
VAL A 271
 None
 1.21A 4po0A-3p4gA:
undetectable		 4po0A-3p4gA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)

(Trypanosoma
brucei) 		PF00085
(Thioredoxin)
PF04777
(Evr1_Alr) 		5 LEU A 268
LEU A 245
VAL A 252
LEU A 326
LEU A 322
 None
 1.12A 4po0A-3qd9A:
undetectable		 4po0A-3qd9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qz1 STEROID
21-HYDROXYLASE

(Bos taurus) 		PF00067
(p450) 		5 LEU A 428
LEU A 287
VAL A 280
LEU A 240
LEU A 260
 HEM  A 500 (-3.8A)
None
None
None
None
 1.09A 4po0A-3qz1A:
undetectable		 4po0A-3qz1A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rac HISTIDINE-TRNA
LIGASE

(Alicyclobacillus
acidocaldarius) 		PF13393
(tRNA-synt_His) 		5 LEU A 237
LEU A 233
VAL A 189
LEU A 193
LEU A 207
 None
None
NA  A 402 (-4.8A)
None
None
 1.11A 4po0A-3racA:
undetectable		 4po0A-3racA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tcx INTERCELLULAR
ADHESION MOLECULE 1

(Homo sapiens) 		PF03921
(ICAM_N) 		5 ASN A  56
VAL A  17
LEU A  11
LEU A  80
VAL A  82
 None
 1.03A 4po0A-3tcxA:
undetectable		 4po0A-3tcxA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vex O-CARBAMOYLTRANSFERA
SE TOBZ

(Streptoalloteichus
tenebrarius) 		PF02543
(Carbam_trans_N)
PF16861
(Carbam_trans_C) 		5 VAL A 307
LEU A 305
ASN A 318
LEU A 321
VAL A 327
 None
 1.00A 4po0A-3vexA:
undetectable		 4po0A-3vexA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vv3 DESEASIN MCP-01

(Pseudoalteromonas
sp. SM9913) 		PF00082
(Peptidase_S8) 		5 LEU A 222
VAL A 320
LEU A 324
LEU A 281
VAL A 285
 None
 1.21A 4po0A-3vv3A:
undetectable		 4po0A-3vv3A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w04 DWARF 88 ESTERASE

(Oryza sativa) 		PF12697
(Abhydrolase_6) 		5 LEU A 292
VAL A  88
LEU A  92
LEU A  74
VAL A  72
 None
 1.09A 4po0A-3w04A:
undetectable		 4po0A-3w04A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6o DYNAMIN-1-LIKE
PROTEIN

(Homo sapiens) 		PF00350
(Dynamin_N)
PF01031
(Dynamin_M) 		5 LEU A 285
LEU A 289
VAL A  46
LEU A  67
LEU A  65
 None
 1.01A 4po0A-3w6oA:
2.8		 4po0A-3w6oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d5c TETRACYCLINE
REPRESSOR PROTEIN
TETR

(Proteus
mirabilis) 		PF00440
(TetR_N)
PF02909
(TetR_C) 		5 LEU A  55
LEU A  51
LEU A   4
ASN A  12
VAL A  36
 None
 1.21A 4po0A-4d5cA:
3.7		 4po0A-4d5cA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpp DIHYDRODIPICOLINATE
SYNTHASE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00701
(DHDPS) 		5 LEU A 291
LEU A 295
ASN A 266
VAL A 346
LEU A  90
 None
None
None
NA  A 401 (-4.8A)
None
 1.13A 4po0A-4dppA:
undetectable		 4po0A-4dppA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana) 		PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		5 LEU A 187
LEU A 167
VAL A 180
LEU A 203
LEU A 177
 None
 1.21A 4po0A-4j0mA:
undetectable		 4po0A-4j0mA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kma GM14141P

(Drosophila
melanogaster) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		5 LEU A 255
LEU A 251
LEU A 174
LEU A 204
VAL A 199
 None
 0.83A 4po0A-4kmaA:
undetectable		 4po0A-4kmaA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyi VIPD

(Legionella
pneumophila) 		PF01734
(Patatin) 		5 LEU A  98
LEU A 103
ASN A 120
VAL A 124
LEU A 193
 None
 1.15A 4po0A-4kyiA:
3.7		 4po0A-4kyiA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkh E3 UBIQUITIN-PROTEIN
LIGASE SSPH1

(Salmonella
enterica) 		no annotation 5 LEU A 279
LEU A 275
VAL A 304
LEU A 309
LEU A 312
 None
 1.19A 4po0A-4nkhA:
2.4		 4po0A-4nkhA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npk EXTENDED
SYNAPTOTAGMIN-2

(Homo sapiens) 		PF00168
(C2) 		5 LEU A 657
LEU A 506
VAL A 479
LEU A 476
VAL A 420
 None
 1.11A 4po0A-4npkA:
undetectable		 4po0A-4npkA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onz PUTATIVE GLYCOSIDE
HYDROLASE

(Bacteroides
ovatus) 		PF04041
(Glyco_hydro_130) 		5 VAL A  86
LEU A  88
LEU A 176
LYS A 177
VAL A 124
 None
 1.18A 4po0A-4onzA:
undetectable		 4po0A-4onzA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p42 EXTENDED
SYNAPTOTAGMIN-2

(Homo sapiens) 		PF00168
(C2)
PF17047
(SMP_LBD) 		5 LEU A 629
LEU A 478
VAL A 451
LEU A 448
VAL A 392
 None
 1.15A 4po0A-4p42A:
undetectable		 4po0A-4p42A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q20 SENSOR PROTEIN DIVL

(Caulobacter
vibrioides) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		5 ASN A 623
VAL A 665
LEU A 680
LEU A 639
VAL A 641
 None
 1.13A 4po0A-4q20A:
undetectable		 4po0A-4q20A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q3k MGS-M1

(unidentified) 		PF00326
(Peptidase_S9)
PF07859
(Abhydrolase_3) 		5 LEU A 233
ASN A 131
LEU A  90
LEU A 122
VAL A 128
 None
 1.20A 4po0A-4q3kA:
undetectable		 4po0A-4q3kA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rk2 PUTATIVE SUGAR ABC
TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Rhizobium etli) 		PF01547
(SBP_bac_1) 		5 LEU A 324
ASN A 314
VAL A  92
LEU A  82
LEU A 103
 None
 1.04A 4po0A-4rk2A:
2.3		 4po0A-4rk2A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3p 4-ALPHA-GLUCANOTRANS
FERASE

(Escherichia
coli) 		PF02446
(Glyco_hydro_77) 		5 LEU A 635
LEU A 683
LEU A 594
ASN A 618
LEU A 617
 None
 1.07A 4po0A-4s3pA:
undetectable		 4po0A-4s3pA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uc0 PURINE NUCLEOSIDE
PHOSPHORYLASE

(Agrobacterium
vitis) 		PF01048
(PNP_UDP_1) 		5 LEU A 253
LEU A 257
VAL A  22
LEU A 103
VAL A 100
 None
 1.14A 4po0A-4uc0A:
undetectable		 4po0A-4uc0A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x28 ACYL-COA
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		no annotation 5 LEU D  98
LEU D 121
VAL D 163
LEU D 199
VAL D 185
 None
 1.16A 4po0A-4x28D:
undetectable		 4po0A-4x28D:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3

(Acinetobacter
baumannii) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		5 LEU A 534
LEU A 536
LEU A 498
LEU A 510
VAL A 505
 None
 1.15A 4po0A-4zxiA:
undetectable		 4po0A-4zxiA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6d DNA POLYMERASE
SLIDING CLAMP

(Thermococcus
gammatolerans) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		5 LEU A 155
VAL A 140
LEU A 136
LEU A 179
VAL A 134
 None
 1.08A 4po0A-5a6dA:
undetectable		 4po0A-5a6dA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az0 UNCHARACTERIZED
PROTEIN

(Bombyx mori) 		PF00248
(Aldo_ket_red) 		5 LEU A 133
LEU A 135
ASN A 196
VAL A 218
LEU A 186
 None
 1.11A 4po0A-5az0A:
undetectable		 4po0A-5az0A:
20.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		5 LEU A 393
ASN A 404
VAL A 408
LEU A 528
LEU A 543
 None
 0.65A 4po0A-5dqfA:
50.0		 4po0A-5dqfA:
71.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fg9 PROTEASOME SUBUNIT
BETA TYPE-2

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome)
PF12465
(Pr_beta_C) 		5 LEU H  34
VAL H   6
LEU H 138
LEU H 154
VAL H 137
 None
 1.15A 4po0A-5fg9H:
undetectable		 4po0A-5fg9H:
17.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		6 LEU A 394
LEU A 398
ASN A 405
VAL A 409
LEU A 529
LEU A 544
 None
 0.76A 4po0A-5ghkA:
46.8		 4po0A-5ghkA:
74.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		6 LEU A 394
LEU A 398
ASN A 405
VAL A 409
LEU A 544
LYS A 545
 None
 0.96A 4po0A-5ghkA:
46.8		 4po0A-5ghkA:
74.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iz5 CYTOSOLIC
PHOSPHOLIPASE A2
DELTA

(Homo sapiens) 		no annotation 5 LEU B 342
LEU B 351
ASN B 457
LEU B 452
LEU B 459
 None
 1.18A 4po0A-5iz5B:
undetectable		 4po0A-5iz5B:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kxj L-ASPARTATE OXIDASE

(Salmonella
enterica) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		5 LEU A 370
LEU A 202
VAL A 235
LEU A 238
LEU A 499
 None
 1.13A 4po0A-5kxjA:
undetectable		 4po0A-5kxjA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN3

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF08375
(Rpn3_C) 		5 ASN S 159
LEU S 146
ASN S  91
LEU S  92
VAL S 142
 None
 1.17A 4po0A-5mpdS:
2.3		 4po0A-5mpdS:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0l RETICULON-4 RECEPTOR

(Mus musculus) 		no annotation 5 LEU A 166
ASN A 164
VAL A 121
LEU A 118
LEU A 112
 None
 1.21A 4po0A-5o0lA:
undetectable		 4po0A-5o0lA:
20.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 5 LEU A 393
ASN A 404
VAL A 408
LEU A 528
LEU A 543
 None
 0.74A 4po0A-5oriA:
51.2		 4po0A-5oriA:
72.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tdy FLAGELLAR M-RING
PROTEIN
FLAGELLAR MOTOR
SWITCH PROTEIN FLIG

(Thermotoga
maritima) 		PF14842
(FliG_N)
no annotation 		6 LEU A  16
LEU B  19
VAL A  31
LEU B  39
LEU B  31
VAL B  36
 None
 1.41A 4po0A-5tdyA:
undetectable		 4po0A-5tdyA:
6.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u2a AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Brucella canis) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		5 LEU A 171
LEU A 165
ASN A 145
VAL A 143
LEU A  98
 None
 1.05A 4po0A-5u2aA:
undetectable		 4po0A-5u2aA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u89 AMINO ACID
ADENYLATION DOMAIN
PROTEIN

(Geobacillus sp.
Y4.1MC1) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF13193
(AMP-binding_C) 		5 LEU A1093
LEU A1097
VAL A1080
LEU A1190
VAL A1185
 None
 0.98A 4po0A-5u89A:
undetectable		 4po0A-5u89A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6o DNA DAMAGE
CHECKPOINT PROTEIN
LCD1

(Saccharomyces
cerevisiae) 		no annotation 5 LEU G 603
LEU G 546
VAL G 552
LEU G 460
LEU G 461
 None
 1.20A 4po0A-5x6oG:
3.5		 4po0A-5x6oG:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 7 LEU A 394
LEU A 398
ASN A 405
VAL A 409
LEU A 529
LEU A 544
LYS A 545
 None
 0.59A 4po0A-5yxeA:
45.4		 4po0A-5yxeA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo sapiens) 		no annotation 5 LEU A1381
ASN A1386
VAL A1553
LEU A1551
LEU A1500
 None
 1.18A 4po0A-6bhcA:
undetectable		 4po0A-6bhcA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6de8 BIFUNCTIONAL PROTEIN
FOLD

(Campylobacter
jejuni) 		no annotation 5 LEU A 177
LEU A 203
VAL A 206
LEU A 214
VAL A 247
 None
 1.15A 4po0A-6de8A:
undetectable		 4po0A-6de8A:
10.34