SIMILAR PATTERNS OF AMINO ACIDS FOR 4PM7_A_CE3A301_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wyx BETA-LACTAMSE TOHO-1

(Escherichia
coli) 		PF13354
(Beta-lactamase2) 		4 CYH A  69
PRO A 167
THR A 235
ASP A 240
 None
 0.64A 4pm7A-2wyxA:
46.0		 4pm7A-2wyxA:
83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3byd BETA-LACTAMASE OXY-1

(Klebsiella
oxytoca) 		PF13354
(Beta-lactamase2) 		4 CYH A  72
PRO A 170
THR A 238
ASP A 242
 None
None
SO4  A 301 (-3.9A)
None
 0.43A 4pm7A-3bydA:
47.2		 4pm7A-3bydA:
74.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dwz BETA-LACTAMASE

(Mycobacterium
tuberculosis) 		PF13354
(Beta-lactamase2) 		4 CYH A  83
PRO A 183
THR A 251
ASP A 255
 DWZ  A 400 (-4.9A)
None
DWZ  A 400 (-3.5A)
None
 0.76A 4pm7A-3dwzA:
41.0		 4pm7A-3dwzA:
45.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e2e BETA-LACTAMASE

(Yersinia
enterocolitica) 		PF13354
(Beta-lactamase2) 		4 CYH A  46
PRO A 144
THR A 212
ASP A 216
 None
 0.36A 4pm7A-5e2eA:
44.3		 4pm7A-5e2eA:
58.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5vpq BETA-LACTAMASE

(Paraburkholderia
phymatum) 		PF13354
(Beta-lactamase2) 		4 CYH A  57
PRO A 156
THR A 226
ASP A 230
 None
None
None
EDO  A 304 (-3.7A)
 0.44A 4pm7A-5vpqA:
41.3		 4pm7A-5vpqA:
48.39