SIMILAR PATTERNS OF AMINO ACIDS FOR 4PD4_C_AOQC4003_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2r | PROTEIN(TRYPTOPHANYL TRNASYNTHETASE) (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 5 | ILE A 183ILE A 253LEU A 248LEU A 241ILE A 213 | None | 1.00A | 4pd4C-1d2rA:undetectable | 4pd4C-1d2rA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fft | UBIQUINOL OXIDASE (Escherichiacoli) |
PF00510(COX3) | 5 | GLY C 147VAL C 150ILE C 113LEU C 70LEU C 77 | None | 1.08A | 4pd4C-1fftC:3.6 | 4pd4C-1fftC:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i6a | HYDROGENPEROXIDE-INDUCIBLEGENES ACTIVATOR (Escherichiacoli) |
PF03466(LysR_substrate) | 5 | VAL A 231ILE A 237LEU A 257TYR A 256LEU A 240 | None | 1.05A | 4pd4C-1i6aA:undetectable | 4pd4C-1i6aA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iwa | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE/OXYGENASE SMALL SUBUNIT (Galdieriapartita) |
PF00101(RuBisCO_small) | 5 | GLY B 41VAL B 101ILE B 42PHE B 85LEU B 84 | None | 0.94A | 4pd4C-1iwaB:undetectable | 4pd4C-1iwaB:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mec | MENGO VIRUS COATPROTEIN (SUBUNITVP1) (Cardiovirus A) |
no annotation | 5 | GLY 1 44VAL 1 238ILE 1 43PRO 1 66LEU 1 225 | None | 1.09A | 4pd4C-1mec1:undetectable | 4pd4C-1mec1:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7r | HYALURONIDASE (Streptococcuspneumoniae) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 5 | GLY A 354ILE A 377ILE A 296LEU A 412ILE A 485 | None | 1.09A | 4pd4C-1n7rA:0.0 | 4pd4C-1n7rA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1naa | CELLOBIOSEDEHYDROGENASE (Phanerochaetechrysosporium) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | GLY A 583VAL A 608ILE A 606LEU A 370ILE A 659 | None | 1.07A | 4pd4C-1naaA:undetectable | 4pd4C-1naaA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qcq | PROTEIN (UBIQUITINCONJUGATING ENZYME) (Saccharomycescerevisiae) |
PF00179(UQ_con) | 5 | PHE A 51ILE A 74PRO A 41LEU A 110ILE A 68 | None | 0.97A | 4pd4C-1qcqA:undetectable | 4pd4C-1qcqA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1u | CHOLINEO-ACETYLTRANSFERASE (Rattusnorvegicus) |
PF00755(Carn_acyltransf) | 5 | GLY A 571ILE A 585LEU A 431TYR A 435LEU A 438 | None | 0.99A | 4pd4C-1t1uA:undetectable | 4pd4C-1t1uA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uf2 | CORE PROTEIN P3 (Rice dwarfvirus) |
PF09231(RDV-p3) | 5 | PHE A 415LEU A 455TYR A 459LEU A 462ILE A 438 | None | 0.95A | 4pd4C-1uf2A:undetectable | 4pd4C-1uf2A:16.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1zrt | CYTOCHROME B (Rhodobactercapsulatus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 8 | GLY C 158ILE C 162ILE C 292PRO C 294PHE C 301TYR C 302LEU C 305ILE C 340 | SMA C 503 (-3.3A)NoneSMA C 503 ( 4.5A)SMA C 503 (-4.1A)SMA C 503 (-4.7A)SMA C 503 (-4.2A)SMA C 503 ( 4.6A)None | 0.93A | 4pd4C-1zrtC:48.6 | 4pd4C-1zrtC:44.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1zrt | CYTOCHROME B (Rhodobactercapsulatus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 8 | GLY C 158ILE C 162PRO C 294PHE C 301TYR C 302LEU C 305MET C 336ILE C 340 | SMA C 503 (-3.3A)NoneSMA C 503 (-4.1A)SMA C 503 (-4.7A)SMA C 503 (-4.2A)SMA C 503 ( 4.6A)SMA C 503 (-3.3A)None | 0.88A | 4pd4C-1zrtC:48.6 | 4pd4C-1zrtC:44.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1zrt | CYTOCHROME B (Rhodobactercapsulatus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 8 | GLY C 158VAL C 161ILE C 162ILE C 292PHE C 301TYR C 302LEU C 305ILE C 340 | SMA C 503 (-3.3A)SMA C 503 (-4.4A)NoneSMA C 503 ( 4.5A)SMA C 503 (-4.7A)SMA C 503 (-4.2A)SMA C 503 ( 4.6A)None | 0.86A | 4pd4C-1zrtC:48.6 | 4pd4C-1zrtC:44.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1zrt | CYTOCHROME B (Rhodobactercapsulatus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 8 | GLY C 158VAL C 161ILE C 162PHE C 301TYR C 302LEU C 305MET C 336ILE C 340 | SMA C 503 (-3.3A)SMA C 503 (-4.4A)NoneSMA C 503 (-4.7A)SMA C 503 (-4.2A)SMA C 503 ( 4.6A)SMA C 503 (-3.3A)None | 0.82A | 4pd4C-1zrtC:48.6 | 4pd4C-1zrtC:44.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d0i | DEHYDROGENASE (Pyrococcushorikoshii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 5 | GLY A 38VAL A 39ILE A 40LEU A 8ILE A 78 | None | 1.08A | 4pd4C-2d0iA:undetectable | 4pd4C-2d0iA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2du7 | O-PHOSPHOSERYL-TRNASYNTHETASE (Methanocaldococcusjannaschii) |
PF01409(tRNA-synt_2d) | 5 | GLY A 482ILE A 42PHE A 380TYR A 381ILE A 418 | None | 0.90A | 4pd4C-2du7A:undetectable | 4pd4C-2du7A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2du7 | O-PHOSPHOSERYL-TRNASYNTHETASE (Methanocaldococcusjannaschii) |
PF01409(tRNA-synt_2d) | 5 | GLY A 482ILE A 484PHE A 380TYR A 381ILE A 418 | None | 1.07A | 4pd4C-2du7A:undetectable | 4pd4C-2du7A:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e7z | ACETYLENE HYDRATASEAHY (Pelobacteracetylenicus) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 5 | GLY A 171ILE A 170PRO A 201LEU A 216TYR A 218 | MGD A 802 (-3.5A)MGD A 802 (-4.7A)MGD A 802 (-4.3A)MGD A 802 (-4.8A)MGD A 802 (-3.9A) | 0.94A | 4pd4C-2e7zA:undetectable | 4pd4C-2e7zA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gq3 | MALATE SYNTHASE G (Mycobacteriumtuberculosis) |
PF01274(Malate_synthase) | 5 | GLY A 651VAL A 652ILE A 653LEU A 643ILE A 605 | None | 1.08A | 4pd4C-2gq3A:2.2 | 4pd4C-2gq3A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h2y | UBIQUITIN-CONJUGATING ENZYME (Plasmodiumfalciparum) |
PF00179(UQ_con) | 5 | GLY A 102VAL A 98ILE A 104TYR A 69LEU A 130 | None | 1.05A | 4pd4C-2h2yA:undetectable | 4pd4C-2h2yA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi9 | PLASMA SERINEPROTEASE INHIBITOR (Homo sapiens) |
PF00079(Serpin) | 5 | VAL A 334ILE A 289ILE A 184PHE A 372ILE A 249 | None | 1.07A | 4pd4C-2hi9A:undetectable | 4pd4C-2hi9A:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivg | CYANATE LYASE (Escherichiacoli) |
PF02560(Cyanate_lyase) | 5 | PRO A 89PHE A 97TYR A 98LEU A 101ILE A 144 | None | 0.98A | 4pd4C-2ivgA:undetectable | 4pd4C-2ivgA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgp | TYROCIDINESYNTHETASE 3 (Brevibacillusbrevis) |
PF00550(PP-binding)PF00668(Condensation) | 5 | GLY A 481LEU A 335TYR A 339LEU A 342ILE A 508 | None | 1.05A | 4pd4C-2jgpA:undetectable | 4pd4C-2jgpA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pwq | UBIQUITINCONJUGATING ENZYME (Plasmodiumyoelii) |
PF00179(UQ_con) | 5 | PHE A 51ILE A 74PRO A 41LEU A 111ILE A 68 | None | 0.97A | 4pd4C-2pwqA:undetectable | 4pd4C-2pwqA:20.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 7 | GLY A 158VAL A 161ILE A 162ILE A 292PRO A 294MET A 336ILE A 340 | SMA A 1 (-3.1A)SMA A 1 (-4.1A)SMA A 1 (-4.5A)SMA A 1 ( 4.7A)SMA A 1 (-3.8A)SMA A 1 (-3.6A)None | 0.85A | 4pd4C-2qjpA:49.8 | 4pd4C-2qjpA:45.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qjp | CYTOCHROME B (Rhodobactersphaeroides) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 9 | GLY A 158VAL A 161ILE A 162PRO A 294PHE A 301TYR A 302LEU A 305MET A 336ILE A 340 | SMA A 1 (-3.1A)SMA A 1 (-4.1A)SMA A 1 (-4.5A)SMA A 1 (-3.8A)NoneSMA A 1 (-4.4A)SMA A 1 ( 4.3A)SMA A 1 (-3.6A)None | 0.60A | 4pd4C-2qjpA:49.8 | 4pd4C-2qjpA:45.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ucz | UBIQUITINCONJUGATING ENZYME (Saccharomycescerevisiae) |
PF00179(UQ_con) | 5 | PHE A 54ILE A 77PRO A 48LEU A 127ILE A 90 | None | 1.05A | 4pd4C-2uczA:undetectable | 4pd4C-2uczA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xpp | IWS1 (Encephalitozooncuniculi) |
PF08711(Med26) | 5 | GLY A 160VAL A 159ILE A 162ILE A 149LEU A 141 | None | 1.05A | 4pd4C-2xppA:undetectable | 4pd4C-2xppA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xz4 | PEPTIDOGLYCAN-RECOGNITION PROTEIN LF (Drosophilamelanogaster) |
PF01510(Amidase_2) | 5 | GLY A 67ILE A 101PHE A 124TYR A 133LEU A 125 | None | 1.00A | 4pd4C-2xz4A:undetectable | 4pd4C-2xz4A:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y8n | 4-HYDROXYPHENYLACETATE DECARBOXYLASELARGE SUBUNIT (Clostridiumscatologenes) |
PF01228(Gly_radical)PF02901(PFL-like) | 5 | GLY A 526VAL A 225ILE A 226PRO A 524ILE A 327 | None | 1.06A | 4pd4C-2y8nA:3.3 | 4pd4C-2y8nA:18.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2yiu | CYTOCHROME B (Paracoccusdenitrificans) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 9 | GLY A 158VAL A 161ILE A 162ILE A 292PRO A 294PHE A 301LEU A 305MET A 336ILE A 340 | SMA A 502 (-3.5A)SMA A 502 (-4.3A)SMA A 502 ( 4.5A)SMA A 502 (-4.6A)SMA A 502 ( 3.8A)NoneSMA A 502 ( 4.4A)SMA A 502 (-3.6A)None | 0.78A | 4pd4C-2yiuA:50.0 | 4pd4C-2yiuA:44.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2yiu | CYTOCHROME B (Paracoccusdenitrificans) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 9 | GLY A 158VAL A 161ILE A 162PRO A 294PHE A 301TYR A 302LEU A 305MET A 336ILE A 340 | SMA A 502 (-3.5A)SMA A 502 (-4.3A)SMA A 502 ( 4.5A)SMA A 502 ( 3.8A)NoneSMA A 502 (-4.5A)SMA A 502 ( 4.4A)SMA A 502 (-3.6A)None | 0.56A | 4pd4C-2yiuA:50.0 | 4pd4C-2yiuA:44.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afl | OLIGO ALGINATE LYASE (Agrobacteriumfabrum) |
PF07940(Hepar_II_III)PF16332(DUF4962) | 5 | VAL A 644ILE A 643ILE A 758PHE A 635ILE A 506 | None | 1.05A | 4pd4C-3aflA:2.3 | 4pd4C-3aflA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c02 | AQUAGLYCEROPORIN (Plasmodiumfalciparum) |
PF00230(MIP) | 6 | GLY A 174VAL A 173ILE A 176LEU A 192LEU A 149ILE A 143 | None | 1.50A | 4pd4C-3c02A:undetectable | 4pd4C-3c02A:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cji | POLYPROTEIN (Senecavirus A) |
PF00073(Rhv)no annotation | 5 | GLY A 8ILE C 206ILE B 50LEU B 53ILE B 214 | None | 1.09A | 4pd4C-3cjiA:undetectable | 4pd4C-3cjiA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cpq | 50S RIBOSOMALPROTEIN L30E (Methanocaldococcusjannaschii) |
PF01248(Ribosomal_L7Ae) | 5 | VAL A 9ILE A 99ILE A 71LEU A 89ILE A 64 | None | 1.04A | 4pd4C-3cpqA:undetectable | 4pd4C-3cpqA:14.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cps | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Cryptosporidiumparvum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | GLY A 21VAL A 109ILE A 108ILE A 99LEU A 126 | None | 0.96A | 4pd4C-3cpsA:undetectable | 4pd4C-3cpsA:24.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cql | ENDOCHITINASE (Carica papaya) |
PF00182(Glyco_hydro_19) | 5 | GLY A 45ILE A 2ILE A 172LEU A 155LEU A 61 | None | 1.00A | 4pd4C-3cqlA:undetectable | 4pd4C-3cqlA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fo8 | TAIL SHEATH PROTEINGP18 (Escherichiavirus T4) |
PF17481(Phage_sheath_1N) | 5 | PHE D 334GLY D 336ILE D 238ILE D 254LEU D 340 | None | 1.09A | 4pd4C-3fo8D:undetectable | 4pd4C-3fo8D:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0g | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB2 (Schizosaccharomycespombe) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | PHE B 38ILE B 190PRO B 156LEU B 402ILE B 49 | None | 1.07A | 4pd4C-3h0gB:undetectable | 4pd4C-3h0gB:14.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h1l | CYTOCHROME B (Gallus gallus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 7 | GLY C 143VAL C 146ILE C 147ILE C 269PRO C 271TYR C 279LEU C 282 | 3H1 C2001 (-3.3A)3H1 C2001 (-4.4A)3H1 C2001 (-4.7A)None3H1 C2001 (-3.8A)3H1 C2001 (-4.2A)3H1 C2001 (-4.9A) | 0.61A | 4pd4C-3h1lC:52.8 | 4pd4C-3h1lC:52.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h1l | CYTOCHROME B (Gallus gallus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 7 | PHE C 129GLY C 143VAL C 146ILE C 147ILE C 269PRO C 271LEU C 282 | 3H1 C2001 ( 4.7A)3H1 C2001 (-3.3A)3H1 C2001 (-4.4A)3H1 C2001 (-4.7A)None3H1 C2001 (-3.8A)3H1 C2001 (-4.9A) | 0.86A | 4pd4C-3h1lC:52.8 | 4pd4C-3h1lC:52.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iau | THREONINE DEAMINASE (Solanumlycopersicum) |
PF00291(PALP) | 5 | GLY A 196ILE A 192PHE A 43TYR A 45LEU A 42 | None | 1.09A | 4pd4C-3iauA:undetectable | 4pd4C-3iauA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kaq | FLAVODOXIN (Desulfovibriodesulfuricans) |
PF00258(Flavodoxin_1) | 5 | GLY A 56ILE A 6LEU A 88LEU A 46MET A 81 | None | 1.02A | 4pd4C-3kaqA:undetectable | 4pd4C-3kaqA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lzd | DPH2 (Pyrococcushorikoshii) |
PF01866(Diphthamide_syn) | 5 | PHE A 320GLY A 187ILE A 182LEU A 292ILE A 222 | None | 1.01A | 4pd4C-3lzdA:undetectable | 4pd4C-3lzdA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m5r | NONSTRUCTURALPROTEIN 1 (Influenza Avirus) |
PF00600(Flu_NS1) | 5 | GLY A 179ILE A 182ILE A 112LEU A 147LEU A 119 | None | 1.05A | 4pd4C-3m5rA:undetectable | 4pd4C-3m5rA:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mos | TRANSKETOLASE (Homo sapiens) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | GLY A 569VAL A 572ILE A 537LEU A 532ILE A 529 | None | 1.02A | 4pd4C-3mosA:undetectable | 4pd4C-3mosA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5f | N-CARBAMOYL-L-AMINOACID HYDROLASE (Geobacillusstearothermophilus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | GLY A 394VAL A 397ILE A 370LEU A 196PHE A 348 | None | 1.08A | 4pd4C-3n5fA:undetectable | 4pd4C-3n5fA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3odp | PUTATIVETAGATOSE-6-PHOSPHATEKETOSE/ALDOSEISOMERASE (Clostridiumnovyi) |
PF01380(SIS) | 5 | GLY A 72VAL A 71ILE A 112LEU A 188ILE A 206 | None | 1.08A | 4pd4C-3odpA:undetectable | 4pd4C-3odpA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opb | SWI5-DEPENDENT HOEXPRESSION PROTEIN 4 (Saccharomycescerevisiae) |
PF11701(UNC45-central) | 5 | GLY A 391VAL A 394ILE A 395TYR A 355LEU A 358 | None | 0.97A | 4pd4C-3opbA:undetectable | 4pd4C-3opbA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oqq | PUTATIVE LIPOPROTEIN (Bacteroidesovatus) |
PF16129(DUF4841)PF16130(DUF4842) | 5 | GLY A 215VAL A 216ILE A 290TYR A 175LEU A 177 | None | 1.06A | 4pd4C-3oqqA:undetectable | 4pd4C-3oqqA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q41 | GLUTAMATE [NMDA]RECEPTOR SUBUNITZETA-1 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 5 | GLY A 286VAL A 287LEU A 91LEU A 138ILE A 116 | None | 1.04A | 4pd4C-3q41A:undetectable | 4pd4C-3q41A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rip | GAMMA-TUBULINCOMPLEX COMPONENT 4 (Homo sapiens) |
PF04130(Spc97_Spc98) | 5 | ILE A 613LEU A 595PHE A 592LEU A 588ILE A 512 | None | 1.02A | 4pd4C-3ripA:6.1 | 4pd4C-3ripA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rsj | BONT/F (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 6 | GLY A1146VAL A1147ILE A1116PHE A1122LEU A1200ILE A1197 | None | 1.38A | 4pd4C-3rsjA:undetectable | 4pd4C-3rsjA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t1u | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Azotobactervinelandii) |
PF00160(Pro_isomerase) | 5 | PHE A 98GLY A 52ILE A 40LEU A 4ILE A 162 | None | 1.10A | 4pd4C-3t1uA:undetectable | 4pd4C-3t1uA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t32 | AMINOTRANSFERASE,CLASS I/II (Bacillusanthracis) |
PF00155(Aminotran_1_2) | 6 | PHE A 120GLY A 353ILE A 115LEU A 130LEU A 110ILE A 99 | None | 1.50A | 4pd4C-3t32A:undetectable | 4pd4C-3t32A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4y | NUCLEAR INHIBITOR OFPROTEIN PHOSPHATASE1SERINE/THREONINE-PROTEIN PHOSPHATASEPP1-ALPHA CATALYTICSUBUNIT (Homo sapiens) |
PF00149(Metallophos)PF16891(STPPase_N)no annotation | 5 | GLY A 67ILE A 65TYR A 70LEU A 73ILE B 210 | None | 1.04A | 4pd4C-3v4yA:undetectable | 4pd4C-3v4yA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrk | CARBONYL SULFIDEHYDROLASE (Thiobacillusthioparus) |
PF00484(Pro_CA) | 5 | GLY A 196ILE A 93ILE A 198LEU A 10LEU A 54 | None | 1.02A | 4pd4C-3vrkA:undetectable | 4pd4C-3vrkA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3we5 | UBIQUITINCONJUGATING ENZYME (Agrocybeaegerita) |
PF00179(UQ_con) | 5 | GLY A 90VAL A 86ILE A 92LEU A 55TYR A 53 | None | 1.00A | 4pd4C-3we5A:undetectable | 4pd4C-3we5A:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3we5 | UBIQUITINCONJUGATING ENZYME (Agrocybeaegerita) |
PF00179(UQ_con) | 5 | GLY A 90VAL A 86ILE A 92TYR A 53LEU A 118 | None | 1.00A | 4pd4C-3we5A:undetectable | 4pd4C-3we5A:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zdu | CYCLIN-DEPENDENTKINASE-LIKE 3 (Homo sapiens) |
PF00069(Pkinase) | 5 | GLY A 188ILE A 262LEU A 110PHE A 107ILE A 292 | None | 1.03A | 4pd4C-3zduA:undetectable | 4pd4C-3zduA:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a39 | METALLO-CARBOXYPEPTIDASE (Pseudomonasaeruginosa) |
PF00246(Peptidase_M14) | 5 | GLY A 360VAL A 363ILE A 259LEU A 203LEU A 255 | None | 1.01A | 4pd4C-4a39A:undetectable | 4pd4C-4a39A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4doo | CHALCONE-FLAVANONEISOMERASE FAMILYPROTEIN (Arabidopsisthaliana) |
PF16035(Chalcone_2) | 5 | VAL A 54ILE A 85ILE A 70LEU A 25ILE A 89 | None | 1.09A | 4pd4C-4dooA:undetectable | 4pd4C-4dooA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4u | MANDALATERACEMASE/MUCONATELACTONIZING ENZYME (unidentified) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | PHE A 25GLY A 313ILE A 351LEU A 370LEU A 366 | None | 0.98A | 4pd4C-4e4uA:undetectable | 4pd4C-4e4uA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e5t | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME, C-TERMINALDOMAIN PROTEIN (Labrenziaalexandrii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | PHE A 25GLY A 319ILE A 357LEU A 376LEU A 372 | None | 1.07A | 4pd4C-4e5tA:undetectable | 4pd4C-4e5tA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ex4 | MALATE SYNTHASE G (Mycobacteriumleprae) |
PF01274(Malate_synthase) | 5 | GLY A 656VAL A 657ILE A 658LEU A 648ILE A 610 | None | 1.07A | 4pd4C-4ex4A:undetectable | 4pd4C-4ex4A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fb5 | PROBABLEOXIDOREDUCTASEPROTEIN (Rhizobium etli) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | GLY A 5VAL A 75ILE A 6LEU A 331ILE A 325 | None | 1.08A | 4pd4C-4fb5A:undetectable | 4pd4C-4fb5A:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ffc | 4-AMINOBUTYRATEAMINOTRANSFERASE(GABT) (Mycobacteroidesabscessus) |
PF00202(Aminotran_3) | 5 | PHE A 62ILE A 14PRO A 43LEU A 402ILE A 441 | None | 1.02A | 4pd4C-4ffcA:undetectable | 4pd4C-4ffcA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fm9 | DNA TOPOISOMERASE2-ALPHA (Homo sapiens) |
PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C) | 5 | PHE A 569GLY A 534ILE A 536LEU A 516ILE A 507 | None | 1.07A | 4pd4C-4fm9A:undetectable | 4pd4C-4fm9A:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n42 | XYLANASE ANDALPHA-AMYLASEINHIBITOR PROTEINISOFORM III (Scadoxusmultiflorus) |
PF00704(Glyco_hydro_18) | 5 | PHE A 38GLY A 75ILE A 74LEU A 83ILE A 138 | None | 1.00A | 4pd4C-4n42A:undetectable | 4pd4C-4n42A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4npk | EXTENDEDSYNAPTOTAGMIN-2 (Homo sapiens) |
PF00168(C2) | 5 | PHE A 391GLY A 416ILE A 418LEU A 499PHE A 489 | None | 0.96A | 4pd4C-4npkA:undetectable | 4pd4C-4npkA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p42 | EXTENDEDSYNAPTOTAGMIN-2 (Homo sapiens) |
PF00168(C2)PF17047(SMP_LBD) | 5 | PHE A 363GLY A 388ILE A 390LEU A 471PHE A 461 | None | 0.95A | 4pd4C-4p42A:undetectable | 4pd4C-4p42A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r0m | MCYG PROTEIN (Microcystisaeruginosa) |
no annotation | 5 | GLY B 234VAL B 238ILE B 235ILE B 34LEU B 87 | None | 0.96A | 4pd4C-4r0mB:undetectable | 4pd4C-4r0mB:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rml | LATROPHILIN-3 (Mus musculus) |
PF02191(OLF) | 5 | VAL A 391ILE A 407PRO A 426TYR A 455LEU A 444 | None | 1.01A | 4pd4C-4rmlA:undetectable | 4pd4C-4rmlA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rnz | CONSERVEDHYPOTHETICALSECRETED PROTEIN (Helicobacterpylori) |
PF01551(Peptidase_M23) | 5 | GLY A 355ILE A 357ILE A 351LEU A 302ILE A 272 | None | 1.07A | 4pd4C-4rnzA:undetectable | 4pd4C-4rnzA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ut1 | FLAGELLARHOOK-ASSOCIATEDPROTEIN (Burkholderiapseudomallei) |
PF06429(Flg_bbr_C) | 5 | PHE A 554GLY A 456ILE A 458LEU A 485ILE A 525 | None | 0.98A | 4pd4C-4ut1A:0.0 | 4pd4C-4ut1A:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yep | LAMININ SUBUNITALPHA-2 (Homo sapiens) |
PF00052(Laminin_B) | 5 | GLY A1278ILE A1276PHE A1241MET A1359ILE A1357 | NoneNoneNoneNoneEDO A1409 ( 2.5A) | 1.05A | 4pd4C-4yepA:undetectable | 4pd4C-4yepA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yeq | LAMININ SUBUNITALPHA-2 (Homo sapiens) |
PF00052(Laminin_B) | 5 | GLY U 103ILE U 101PHE U 66MET U 184ILE U 182 | None | 0.98A | 4pd4C-4yeqU:undetectable | 4pd4C-4yeqU:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0n | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Streptobacillusmoniliformis) |
PF13407(Peripla_BP_4) | 5 | GLY A 98VAL A 101ILE A 102LEU A 88ILE A 296 | None | 1.02A | 4pd4C-4z0nA:undetectable | 4pd4C-4z0nA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bq9 | UNCHARACTERIZEDPROTEIN (Legionellapneumophila) |
PF12252(SidE) | 6 | PHE A 44GLY A 67ILE A 56LEU A 85PHE A 88LEU A 90 | None | 1.49A | 4pd4C-5bq9A:undetectable | 4pd4C-5bq9A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5btx | LPG1496 (Legionellapneumophila) |
no annotation | 6 | PHE A 44GLY A 67ILE A 56LEU A 85PHE A 88LEU A 90 | None | 1.39A | 4pd4C-5btxA:undetectable | 4pd4C-5btxA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 5 | GLY A1091ILE A1143LEU A1516PHE A1519TYR A1520 | None | 1.01A | 4pd4C-5d0fA:undetectable | 4pd4C-5d0fA:13.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dnw | SHKAI2IB (Strigahermonthica) |
PF12697(Abhydrolase_6) | 5 | PHE A 91GLY A 23LEU A 77TYR A 73LEU A 70 | None | 1.05A | 4pd4C-5dnwA:undetectable | 4pd4C-5dnwA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e3t | PHOSPHATIDYLINOSITOL-4-PHOSPHATE5-KINASE, TYPE I,ALPHA (Danio rerio) |
PF01504(PIP5K) | 5 | PHE A 131ILE A 379LEU A 192PHE A 189LEU A 185 | None | 0.92A | 4pd4C-5e3tA:undetectable | 4pd4C-5e3tA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gwj | DNA TOPOISOMERASE2-BETA (Homo sapiens) |
PF00521(DNA_topoisoIV)PF01751(Toprim)PF16898(TOPRIM_C) | 5 | PHE A 585GLY A 550ILE A 552LEU A 532ILE A 523 | None | 0.99A | 4pd4C-5gwjA:2.1 | 4pd4C-5gwjA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb4 | NUP192,NUCLEOPORINNUP192 (Chaetomiumthermophilum) |
PF11894(Nup192) | 5 | GLY B1198ILE B1200ILE B1213LEU B1124ILE B1075 | None | 1.06A | 4pd4C-5hb4B:undetectable | 4pd4C-5hb4B:12.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hs1 | LANOSTEROL 14-ALPHADEMETHYLASE (Saccharomycescerevisiae) |
PF00067(p450) | 5 | GLY A 108VAL A 112PRO A 410LEU A 461ILE A 452 | None | 1.05A | 4pd4C-5hs1A:undetectable | 4pd4C-5hs1A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j57 | VHH SINGLE CHAINANTIBODY V5E1 (Vicugna pacos) |
PF07686(V-set) | 5 | GLY B 114VAL B 115TYR B 32LEU B 29ILE B 70 | None | 1.05A | 4pd4C-5j57B:undetectable | 4pd4C-5j57B:15.61 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5nmi | CYTOCHROME B (Bos taurus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 6 | PHE C 128GLY C 142ILE C 268TYR C 278LEU C 281ILE C 298 | None | 1.24A | 4pd4C-5nmiC:51.6 | 4pd4C-5nmiC:50.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nv3 | RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN (Rhodobactersphaeroides) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 6 | PHE A 201GLY A 239VAL A 265ILE A 266LEU A 171ILE A 157 | None | 1.44A | 4pd4C-5nv3A:undetectable | 4pd4C-5nv3A:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o1p | ALPHA-AMINOADIPICSEMIALDEHYDESYNTHASE,MITOCHONDRIAL (Homo sapiens) |
PF03435(Sacchrp_dh_NADP)PF16653(Sacchrp_dh_C) | 5 | ILE A 903ILE A 911PRO A 877LEU A 601ILE A 579 | None | 0.97A | 4pd4C-5o1pA:undetectable | 4pd4C-5o1pA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5weg | UTP--GLUCOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Saccharumhybrid cultivar) |
no annotation | 5 | GLY A 355VAL A 65ILE A 356LEU A 243ILE A 237 | None | 1.08A | 4pd4C-5wegA:undetectable | 4pd4C-5wegA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xru | ADENYLATE KINASE (Nototheniacoriiceps) |
no annotation | 5 | GLY A 94ILE A 92LEU A 42LEU A 73ILE A 81 | AP5 A 201 (-4.4A)NoneNoneNoneNone | 1.06A | 4pd4C-5xruA:undetectable | 4pd4C-5xruA:11.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6axe | MALATE SYNTHASE G (Mycobacteriummarinum) |
PF01274(Malate_synthase) | 5 | GLY A 655VAL A 656ILE A 657LEU A 647ILE A 609 | None | 1.06A | 4pd4C-6axeA:undetectable | 4pd4C-6axeA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PHOSPHATIDYLINOSITOL4-KINASE III ALPHA(PI4KA) (Homo sapiens) |
no annotation | 5 | PHE A1872GLY A2023ILE A2074LEU A1949ILE A1972 | None | 0.84A | 4pd4C-6bq1A:1.7 | 4pd4C-6bq1A:0.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfp | VCA0883 (Vibrio cholerae) |
no annotation | 5 | GLY A 227VAL A 211ILE A 186MET A 175ILE A 172 | None | 1.04A | 4pd4C-6dfpA:undetectable | 4pd4C-6dfpA:9.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6egx | STRUCTURAL PROTEINVP1 (Sacbrood virus) |
no annotation | 5 | ILE A 58ILE A 144LEU A 49MET A 209ILE A 106 | None | 1.06A | 4pd4C-6egxA:undetectable | 4pd4C-6egxA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkh | ATP SYNTHASE EPSILONCHAIN, CHLOROPLASTIC (Spinaciaoleracea) |
no annotation | 5 | GLY e 65VAL e 78ILE e 46LEU e 24LEU e 60 | None | 1.06A | 4pd4C-6fkhe:undetectable | 4pd4C-6fkhe:11.95 |