SIMILAR PATTERNS OF AMINO ACIDS FOR 4OT2_A_NPSA602_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aei ANNEXIN XII

(Hydra vulgaris) 		PF00191
(Annexin) 		4 ARG A  23
LEU A  63
LYS A  61
SER A  69
 None
 1.14A 4ot2A-1aeiA:
1.2		 4ot2A-1aeiA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhw XYLOSE ISOMERASE

(Actinoplanes
missouriensis) 		PF01261
(AP_endonuc_2) 		4 ARG A 326
ALA A 386
ASP A 273
SER A 338
 None
 1.12A 4ot2A-1bhwA:
undetectable		 4ot2A-1bhwA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bjx PROTEIN DISULFIDE
ISOMERASE

(Homo sapiens) 		PF13848
(Thioredoxin_6) 		4 ALA A 161
ASP A 164
LEU A 209
LYS A 213
 None
 1.00A 4ot2A-1bjxA:
undetectable		 4ot2A-1bjxA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c1d L-PHENYLALANINE
DEHYDROGENASE

(Rhodococcus sp.) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 ALA A  43
ASP A 125
LEU A  83
SER A  89
 None
 1.13A 4ot2A-1c1dA:
undetectable		 4ot2A-1c1dA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4e VANCOMYCIN/TEICOPLAN
IN A-TYPE RESISTANCE
PROTEIN VANA

(Enterococcus
faecium) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 ARG B 290
ASP B 292
LEU B 309
SER B  23
 PHY  B 355 (-3.2A)
PHY  B 355 ( 4.7A)
None
None
 1.03A 4ot2A-1e4eB:
1.0		 4ot2A-1e4eB:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f80 HOLO-(ACYL CARRIER
PROTEIN) SYNTHASE

(Bacillus
subtilis) 		PF01648
(ACPS) 		4 ALA A  51
ASP A   8
LEU A  12
SER A  17
 None
 1.15A 4ot2A-1f80A:
undetectable		 4ot2A-1f80A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gy8 UDP-GALACTOSE
4-EPIMERASE

(Trypanosoma
brucei) 		PF01370
(Epimerase) 		4 ALA A  94
ASP A 135
LEU A 284
SER A  -1
 None
 0.70A 4ot2A-1gy8A:
undetectable		 4ot2A-1gy8A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h81 POLYAMINE OXIDASE

(Zea mays) 		PF01593
(Amino_oxidase) 		4 ARG A   6
ASP A  30
LEU A  34
SER A 255
 None
 1.06A 4ot2A-1h81A:
undetectable		 4ot2A-1h81A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htq GLUTAMINE SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 ALA A 377
ASP A 424
LEU A 301
SER A 360
 None
 1.07A 4ot2A-1htqA:
0.0		 4ot2A-1htqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1igq TRANSCRIPTIONAL
REPRESSOR PROTEIN
KORB

(Escherichia
coli) 		PF06613
(KorB_C) 		4 ARG A 316
ALA A 318
ASP A 338
LEU A 334
 None
 0.99A 4ot2A-1igqA:
undetectable		 4ot2A-1igqA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k32 TRICORN PROTEASE

(Thermoplasma
acidophilum) 		PF03572
(Peptidase_S41)
PF07676
(PD40)
PF14684
(Tricorn_C1)
PF14685
(Tricorn_PDZ) 		4 ARG A  85
ALA A  94
ASP A  47
LEU A 146
 None
 1.06A 4ot2A-1k32A:
undetectable		 4ot2A-1k32A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1prx HORF6

(Homo sapiens) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 ALA A  11
ASP A 140
LEU A   5
SER A 146
 None
 1.03A 4ot2A-1prxA:
undetectable		 4ot2A-1prxA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ryy ALPHA-AMINO ACID
ESTER HYDROLASE

(Acetobacter
pasteurianus) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 ARG A 269
ALA A 488
ASP A 274
SER A 256
 None
 1.14A 4ot2A-1ryyA:
undetectable		 4ot2A-1ryyA:
22.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens) 		PF00273
(Serum_albumin) 		5 ARG A 209
ALA A 213
ASP A 324
LEU A 347
SER A 480
 DKA  A1001 ( 4.6A)
DKA  A1001 ( 4.0A)
DKA  A1001 (-4.7A)
DKA  A1002 ( 4.3A)
DKA  A1002 (-3.4A)
 0.54A 4ot2A-1tf0A:
46.8		 4ot2A-1tf0A:
76.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w07 ACYL-COA OXIDASE

(Arabidopsis
thaliana) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		4 ARG A 597
ALA A 308
ASP A 326
LEU A   7
 None
 0.90A 4ot2A-1w07A:
undetectable		 4ot2A-1w07A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdw TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Pyrococcus
furiosus) 		PF00290
(Trp_syntA) 		4 ARG A 185
ALA A 186
ASP A 146
LEU A 162
 None
 0.89A 4ot2A-1wdwA:
undetectable		 4ot2A-1wdwA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xj5 SPERMIDINE SYNTHASE
1

(Arabidopsis
thaliana) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 ARG A 226
ALA A 197
LEU A 115
SER A 143
 None
 0.83A 4ot2A-1xj5A:
undetectable		 4ot2A-1xj5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xup GLYCEROL KINASE

(Enterococcus
casseliflavus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ARG O 143
ALA O 139
LEU O 192
SER O 212
 None
 1.04A 4ot2A-1xupO:
undetectable		 4ot2A-1xupO:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE

(Sarocladium
strictum) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 ARG A 422
ALA A 323
ASP A 378
LEU A 326
 None
 1.06A 4ot2A-1zr6A:
undetectable		 4ot2A-1zr6A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3n PUTATIVE
GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF01380
(SIS) 		4 ARG A 319
ALA A 196
ASP A 318
LYS A 326
 None
 1.12A 4ot2A-2a3nA:
undetectable		 4ot2A-2a3nA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aa4 PUTATIVE
N-ACETYLMANNOSAMINE
KINASE

(Escherichia
coli) 		PF00480
(ROK) 		4 ARG A  27
ALA A  15
ASP A 276
LEU A  48
 None
 1.09A 4ot2A-2aa4A:
undetectable		 4ot2A-2aa4A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ev2 HYPOTHETICAL PROTEIN
RV1264/MT1302

(Mycobacterium
tuberculosis) 		PF16701
(Ad_Cy_reg) 		4 ARG A  70
ALA A  69
ASP A  99
LEU A  83
 None
 0.97A 4ot2A-2ev2A:
undetectable		 4ot2A-2ev2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f5x BUGD

(Bordetella
pertussis) 		PF03401
(TctC) 		4 ARG A 106
ALA A 105
ASP A 108
LEU A 117
 None
 1.08A 4ot2A-2f5xA:
undetectable		 4ot2A-2f5xA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fon PEROXISOMAL ACYL-COA
OXIDASE 1A

(Solanum
lycopersicum) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		5 ARG A 597
ALA A 308
ASP A 326
LEU A   7
SER A 602
 None
 1.09A 4ot2A-2fonA:
undetectable		 4ot2A-2fonA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 ARG A 200
ALA A 182
ASP A 185
LEU A 171
 None
 0.95A 4ot2A-2gmhA:
2.8		 4ot2A-2gmhA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h4t CARNITINE
O-PALMITOYLTRANSFERA
SE II, MITOCHONDRIAL

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 ALA A 379
ASP A 213
LEU A 220
SER A 223
 None
 1.01A 4ot2A-2h4tA:
undetectable		 4ot2A-2h4tA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jk9 SPRY
DOMAIN-CONTAINING
SOCS BOX PROTEIN 1

(Homo sapiens) 		PF00622
(SPRY) 		4 ARG A  88
ALA A  86
ASP A  60
LEU A 132
 None
 1.11A 4ot2A-2jk9A:
undetectable		 4ot2A-2jk9A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lqv PROTEIN YEBF

(Escherichia
coli) 		PF13995
(YebF) 		4 ARG A  55
ALA A  73
ASP A  70
LEU A  91
 None
 1.13A 4ot2A-2lqvA:
undetectable		 4ot2A-2lqvA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwq PROBABLE SHORT-CHAIN
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00106
(adh_short) 		4 ARG A  20
ALA A  19
LEU A  31
SER A  47
 None
 1.11A 4ot2A-2nwqA:
undetectable		 4ot2A-2nwqA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1e YCDH

(Bacillus
subtilis) 		PF01297
(ZnuA) 		4 ARG A 177
ALA A 180
ASP A 173
LEU A 204
 None
 1.15A 4ot2A-2o1eA:
2.6		 4ot2A-2o1eA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q9t DING

(Pseudomonas
fluorescens) 		PF12849
(PBP_like_2) 		4 ALA A 226
LEU A 108
LYS A 230
SER A 128
 None
 1.06A 4ot2A-2q9tA:
undetectable		 4ot2A-2q9tA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vak SIGMA A

(Avian
orthoreovirus) 		PF03084
(Sigma_1_2) 		4 ARG A 252
ALA A 369
ASP A 257
LEU A 341
 None
 1.02A 4ot2A-2vakA:
undetectable		 4ot2A-2vakA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhq NTPASE P4

(Pseudomonas
phage phi12) 		PF11602
(NTPase_P4) 		4 ALA A  48
ASP A 217
LEU A  99
SER A  82
 None
 0.99A 4ot2A-2vhqA:
undetectable		 4ot2A-2vhqA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wuq BETA-LACTAMASE
REGULATORY PROTEIN
BLAB

(Streptomyces
cacaoi) 		PF13354
(Beta-lactamase2) 		4 ARG A 306
ALA A 302
ASP A 307
LEU A 240
 None
 0.90A 4ot2A-2wuqA:
undetectable		 4ot2A-2wuqA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wxz ANGIOTENSINOGEN

(Rattus
norvegicus) 		PF00079
(Serpin) 		4 ARG A 445
ALA A  98
ASP A 447
LEU A  88
 None
 0.97A 4ot2A-2wxzA:
undetectable		 4ot2A-2wxzA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxh MAZG-RELATED PROTEIN

(Thermotoga
maritima) 		PF03819
(MazG) 		4 ARG A  70
ALA A  66
ASP A  71
LEU A  63
 None
 1.13A 4ot2A-2yxhA:
3.3		 4ot2A-2yxhA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0f XYLOGLUCANASE

(Geotrichum sp.
M128) 		no annotation 4 ARG A 335
ASP A 420
LEU A 402
SER A 311
 None
 1.10A 4ot2A-3a0fA:
undetectable		 4ot2A-3a0fA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8u OMEGA-AMINO
ACID--PYRUVATE
AMINOTRANSFERASE

(Pseudomonas
putida) 		PF00202
(Aminotran_3) 		4 ARG X 435
ALA X 439
LEU X 406
SER X  55
 None
 1.12A 4ot2A-3a8uX:
undetectable		 4ot2A-3a8uX:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ccf CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE

(Trichormus
variabilis) 		PF08241
(Methyltransf_11) 		4 ARG A  91
ALA A 117
ASP A  89
LEU A 108
 None
 1.06A 4ot2A-3ccfA:
undetectable		 4ot2A-3ccfA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ARG A 151
ALA A 150
ASP A 145
LEU A 159
 None
 1.11A 4ot2A-3g25A:
undetectable		 4ot2A-3g25A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxk GOOSE-TYPE LYSOZYME
1

(Gadus morhua) 		PF01464
(SLT) 		4 ARG A 180
ALA A  33
ASP A 176
LEU A  26
 None
 1.11A 4ot2A-3gxkA:
undetectable		 4ot2A-3gxkA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3he0 TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Vibrio
parahaemolyticus) 		PF00440
(TetR_N)
PF16295
(TetR_C_10) 		4 ARG A  66
ALA A  70
LEU A  95
SER A 104
 None
 1.06A 4ot2A-3he0A:
2.3		 4ot2A-3he0A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbz SERINE/THREONINE-PRO
TEIN KINASE MTOR

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08771
(FRB_dom) 		4 ARG A1987
ALA A1991
ASP A1947
LEU A1976
 None
 1.04A 4ot2A-3jbzA:
3.4		 4ot2A-3jbzA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3p MANNOSYL-3-PHOSPHOGL
YCERATE SYNTHASE

(Rubrobacter
xylanophilus) 		PF00535
(Glycos_transf_2) 		4 ARG A 278
ALA A 274
ASP A 236
LEU A 322
 None
 1.14A 4ot2A-3o3pA:
undetectable		 4ot2A-3o3pA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p02 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14274
(DUF4361)
PF16343
(DUF4973) 		4 ARG A 171
ALA A 144
ASP A  47
LEU A  87
 None
 1.13A 4ot2A-3p02A:
undetectable		 4ot2A-3p02A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r2g INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE

(Legionella
pneumophila) 		PF00478
(IMPDH) 		4 ARG A 109
ALA A 105
ASP A 110
LEU A 102
 None
 1.11A 4ot2A-3r2gA:
undetectable		 4ot2A-3r2gA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti2 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Vibrio cholerae) 		PF00275
(EPSP_synthase) 		4 ARG A  51
ASP A  48
LEU A  44
SER A  67
 None
 0.80A 4ot2A-3ti2A:
undetectable		 4ot2A-3ti2A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlk FERRIENTEROBACTIN-BI
NDING PERIPLASMIC
PROTEIN

(Escherichia
coli) 		PF01497
(Peripla_BP_2) 		4 ALA A  93
ASP A  81
LEU A  61
SER A  51
 None
 0.76A 4ot2A-3tlkA:
undetectable		 4ot2A-3tlkA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3toj SET1/ASH2 HISTONE
METHYLTRANSFERASE
COMPLEX SUBUNIT ASH2

(Homo sapiens) 		PF00622
(SPRY) 		4 ARG A 317
ALA A 471
ASP A 293
LEU A 357
 None
 0.91A 4ot2A-3tojA:
undetectable		 4ot2A-3tojA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u6r ANTIBODY 1:7 (HEAVY
CHAIN)

(Homo sapiens) 		no annotation 4 ARG H  34
ALA H  82
ASP H  77
SER H  72
 None
 1.12A 4ot2A-3u6rH:
undetectable		 4ot2A-3u6rH:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF00171
(Aldedh) 		4 ARG A  64
ALA A  68
ASP A  87
LEU A  79
 None
 0.94A 4ot2A-3vz0A:
undetectable		 4ot2A-3vz0A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wyh LYSOZYME G

(Struthio
camelus) 		PF01464
(SLT) 		4 ARG A 176
ALA A  33
ASP A 172
LEU A  26
 None
 1.12A 4ot2A-3wyhA:
undetectable		 4ot2A-3wyhA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akx EXOU

(Pseudomonas
aeruginosa) 		PF01734
(Patatin) 		4 ARG B 515
ALA B 514
ASP B 490
LEU B 561
 None
 0.98A 4ot2A-4akxB:
2.7		 4ot2A-4akxB:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cmf AMINOTRANSFERASE

([Nectria]
haematococca) 		PF01063
(Aminotran_4) 		4 ARG A  14
ALA A  12
ASP A 111
LYS A   6
 None
 1.10A 4ot2A-4cmfA:
undetectable		 4ot2A-4cmfA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4el8 GLYCOSIDE HYDROLASE
FAMILY 48

(Caldicellulosiruptor
bescii) 		PF02011
(Glyco_hydro_48) 		4 ARG A 548
ASP A 550
LEU A  41
SER A  37
 None
 1.04A 4ot2A-4el8A:
undetectable		 4ot2A-4el8A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f7a PUTATIVE
UNCHARACTERIZED
PROTEIN

(Bacteroides
vulgatus) 		PF12741
(SusD-like) 		4 ARG A 304
ALA A 399
ASP A 302
SER A 263
 None
 1.13A 4ot2A-4f7aA:
undetectable		 4ot2A-4f7aA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fus RTX TOXINS AND
RELATED CA2+-BINDING
PROTEIN

(Hahella
chejuensis) 		PF02011
(Glyco_hydro_48) 		4 ARG A 584
ASP A 586
LEU A  69
SER A  65
 GOL  A 804 ( 4.8A)
GOL  A 804 (-3.5A)
None
None
 1.15A 4ot2A-4fusA:
undetectable		 4ot2A-4fusA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdz UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		PF14059
(DUF4251) 		4 ALA A 163
ASP A 160
LEU A  70
SER A  87
 None
 0.95A 4ot2A-4gdzA:
undetectable		 4ot2A-4gdzA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxk OXIDOREDUCTASE

(Rhodococcus
opacus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ARG A 121
ALA A 125
ASP A 301
LEU A 295
 None
 0.75A 4ot2A-4jxkA:
undetectable		 4ot2A-4jxkA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpn NUCLEOSIDE
N-RIBOHYDROLASE 1

(Physcomitrella
patens) 		PF01156
(IU_nuc_hydro) 		4 ARG A  73
ALA A  71
ASP A  75
SER A  40
 None
 1.15A 4ot2A-4kpnA:
undetectable		 4ot2A-4kpnA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lbw ELONGATION FACTOR
TU-A

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 ALA A  29
ASP A  81
LEU A 179
SER A 174
 None
MG  A 502 ( 4.0A)
None
GNP  A 501 (-2.7A)
 1.15A 4ot2A-4lbwA:
undetectable		 4ot2A-4lbwA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mcx ANTIDOTE PROTEIN
KILLER PROTEIN

(Proteus
vulgaris) 		PF01381
(HTH_3)
PF05015
(HigB-like_toxin) 		4 ARG A  15
ALA A  14
ASP B  32
LEU A  42
 None
 1.07A 4ot2A-4mcxA:
undetectable		 4ot2A-4mcxA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nuz ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE F2

(Streptococcus
pyogenes) 		no annotation 4 ALA A 147
ASP A 228
LEU A 140
SER A 136
 None
 1.12A 4ot2A-4nuzA:
3.5		 4ot2A-4nuzA:
22.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		4 ALA A 213
ASP A 324
LEU A 347
LYS A 351
 NPS  A 602 (-3.3A)
NPS  A 602 ( 4.4A)
NPS  A 602 ( 4.2A)
None
 0.57A 4ot2A-4po0A:
49.9		 4ot2A-4po0A:
70.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		4 ALA A 213
LEU A 347
LYS A 351
SER A 480
 NPS  A 602 (-3.3A)
NPS  A 602 ( 4.2A)
None
None
 0.56A 4ot2A-4po0A:
49.9		 4ot2A-4po0A:
70.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus) 		PF00273
(Serum_albumin) 		4 ARG A 209
ALA A 213
ASP A 324
LEU A 347
 NPS  A 602 (-3.6A)
NPS  A 602 (-3.3A)
NPS  A 602 ( 4.4A)
NPS  A 602 ( 4.2A)
 0.74A 4ot2A-4po0A:
49.9		 4ot2A-4po0A:
70.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pqi IN2-1 FAMILY
PROTEIN, GLUTATHIONE
TRANSFERASE LAMBDA3

(Populus
trichocarpa) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 ARG A 205
ALA A 150
ASP A 155
LEU A 146
 None
 1.14A 4ot2A-4pqiA:
2.6		 4ot2A-4pqiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u48 PUTATIVE INNER
MEMBRANE LIPOPROTEIN

(Salmonella
enterica) 		PF00207
(A2M)
PF01835
(A2M_N)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl)
PF11974
(MG1) 		4 ARG A1363
ALA A1330
ASP A1379
SER A1290
 None
 0.99A 4ot2A-4u48A:
2.7		 4ot2A-4u48A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uug AMINE TRANSAMINASE

(Aspergillus
fumigatus) 		PF01063
(Aminotran_4) 		4 ARG A  14
ALA A  13
ASP A 111
LYS A   6
 None
 0.78A 4ot2A-4uugA:
undetectable		 4ot2A-4uugA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wab PROSTAGLANDIN E
SYNTHASE,LEUKOTRIENE
C4 SYNTHASE

(Homo sapiens) 		PF01124
(MAPEG) 		4 ARG A  70
ALA A  71
LEU A 118
LYS A 120
 None
 0.94A 4ot2A-4wabA:
2.4		 4ot2A-4wabA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xe3 CYTOCHROME P-450

(Streptomyces
antibioticus) 		PF00067
(p450) 		4 ARG A 172
ALA A 155
ASP A 169
LEU A 127
 None
 1.07A 4ot2A-4xe3A:
undetectable		 4ot2A-4xe3A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xia D-XYLOSE ISOMERASE

(Arthrobacter
sp. NRRL B3728) 		PF01261
(AP_endonuc_2) 		4 ARG A 326
ALA A 386
ASP A 272
SER A 338
 None
 0.90A 4ot2A-4xiaA:
undetectable		 4ot2A-4xiaA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yl0 PROSTAGLANDIN E
SYNTHASE

(Homo sapiens) 		PF01124
(MAPEG) 		4 ARG A  70
ALA A  71
LEU A 118
LYS A 120
 None
None
PEG  A 206 ( 4.0A)
BOG  A 204 (-4.0A)
 0.99A 4ot2A-4yl0A:
3.0		 4ot2A-4yl0A:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zwl BETAINE-ALDEHYDE
DEHYDROGENASE

(Staphylococcus
aureus) 		PF00171
(Aldedh) 		4 ARG A  87
ALA A  91
ASP A 110
LEU A 102
 None
 0.82A 4ot2A-4zwlA:
undetectable		 4ot2A-4zwlA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzp CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
purpureum) 		PF00840
(Glyco_hydro_7) 		4 ALA A 245
ASP A 172
LEU A 377
SER A 194
 None
 1.15A 4ot2A-4zzpA:
undetectable		 4ot2A-4zzpA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		4 ARG A  28
ALA A 485
ASP A 490
LEU A 482
 None
 1.14A 4ot2A-5a29A:
3.0		 4ot2A-5a29A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5b DCC-INTERACTING
PROTEIN 13-ALPHA
DCC-INTERACTING
PROTEIN 13-BETA

(Homo sapiens) 		PF00169
(PH)
PF16746
(BAR_3) 		4 ARG B  46
ALA B  50
LEU A  54
SER A  97
 None
 1.08A 4ot2A-5c5bB:
3.0		 4ot2A-5c5bB:
22.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 ALA A 212
ASP A 323
LEU A 346
LYS A 350
 CZE  A 613 ( 3.7A)
CZE  A 613 ( 4.7A)
CZE  A 613 ( 3.8A)
CZE  A 613 (-4.1A)
 1.05A 4ot2A-5dqfA:
54.7		 4ot2A-5dqfA:
99.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 ALA A 212
ASP A 323
LEU A 346
SER A 479
 CZE  A 613 ( 3.7A)
CZE  A 613 ( 4.7A)
CZE  A 613 ( 3.8A)
None
 0.61A 4ot2A-5dqfA:
54.7		 4ot2A-5dqfA:
99.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus) 		PF00273
(Serum_albumin) 		4 ARG A 208
ALA A 212
LEU A 346
SER A 479
 CZE  A 613 ( 3.5A)
CZE  A 613 ( 3.7A)
CZE  A 613 ( 3.8A)
None
 0.94A 4ot2A-5dqfA:
54.7		 4ot2A-5dqfA:
99.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7s LON PROTEASE

(Meiothermus
taiwanensis) 		PF05362
(Lon_C) 		4 ARG A 503
ALA A 502
ASP A 524
LEU A 547
 None
 1.06A 4ot2A-5e7sA:
undetectable		 4ot2A-5e7sA:
18.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus) 		PF00273
(Serum_albumin) 		5 ALA A 213
ASP A 324
LEU A 347
LYS A 351
SER A 480
 None
 0.66A 4ot2A-5ghkA:
47.2		 4ot2A-5ghkA:
75.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9f CRISPR SYSTEM
CASCADE SUBUNIT CASA

(Escherichia
coli) 		PF09481
(CRISPR_Cse1) 		4 ARG A  40
ALA A 147
ASP A  42
LEU A 117
 None
 1.06A 4ot2A-5h9fA:
2.2		 4ot2A-5h9fA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ho4 HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEINS
A2/B1

(Homo sapiens) 		PF00076
(RRM_1) 		4 ARG A  95
ALA A  78
ASP A 164
SER A  71
 None
 1.10A 4ot2A-5ho4A:
undetectable		 4ot2A-5ho4A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jju UNCHARACTERIZED
PROTEIN RV2837C

(Mycobacterium
tuberculosis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 ALA A  46
ASP A 106
LEU A  80
SER A 259
 None
MN  A1001 ( 2.6A)
None
None
 1.09A 4ot2A-5jjuA:
undetectable		 4ot2A-5jjuA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnb POLY(A) RNA
POLYMERASE GLD-2
RNP (RRM RNA BINDING
DOMAIN) CONTAINING

(Caenorhabditis
elegans) 		PF03828
(PAP_assoc)
no annotation 		4 ARG A 574
ALA E 204
ASP E 208
SER A 582
 None
 1.14A 4ot2A-5jnbA:
undetectable		 4ot2A-5jnbA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3j ACYL-COENZYME A
OXIDASE

(Caenorhabditis
elegans) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		5 ARG A 598
ALA A 316
ASP A 334
LEU A  14
SER A 603
 None
 1.19A 4ot2A-5k3jA:
2.6		 4ot2A-5k3jA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mea CELL DIVISION CYCLE
PROTEIN CDT1

(Saccharomyces
cerevisiae) 		no annotation 4 ALA A 202
ASP A  55
LEU A  44
LYS A  46
 None
 1.11A 4ot2A-5meaA:
undetectable		 4ot2A-5meaA:
22.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus) 		no annotation 5 ARG A 208
ALA A 212
ASP A 323
LEU A 346
SER A 479
 None
 0.50A 4ot2A-5oriA:
50.3		 4ot2A-5oriA:
75.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ul4 OXSB PROTEIN

(Bacillus
megaterium) 		PF02310
(B12-binding) 		4 ARG A 399
ALA A 398
ASP A 401
SER A 310
 None
 1.07A 4ot2A-5ul4A:
undetectable		 4ot2A-5ul4A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vae ACCESSORY SEC SYSTEM
PROTEIN ASP1

(Streptococcus
gordonii) 		no annotation 4 ARG A 152
ALA A  60
ASP A 150
LEU A  53
 None
 0.98A 4ot2A-5vaeA:
undetectable		 4ot2A-5vaeA:
8.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w75 ELONGATION FACTOR TU

(Thermotoga
neapolitana) 		no annotation 4 ALA A  30
ASP A  81
LEU A 179
SER A 174
 None
MG  A 402 ( 4.0A)
None
GDP  A 401 (-3.0A)
 1.11A 4ot2A-5w75A:
undetectable		 4ot2A-5w75A:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7q CONSENSUS ELONGATION
FACTOR

(synthetic
construct) 		no annotation 4 ALA A  30
ASP A  81
LEU A 179
SER A 174
 None
GDP  A 402 ( 4.8A)
None
GDP  A 402 (-2.9A)
 1.11A 4ot2A-5w7qA:
undetectable		 4ot2A-5w7qA:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbf METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER (TLPC)

(Helicobacter
pylori) 		no annotation 4 ARG A 113
ALA A 105
ASP A  83
LEU A 169
 None
 0.88A 4ot2A-5wbfA:
undetectable		 4ot2A-5wbfA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y4j XYLOSE ISOMERASE

(Streptomyces
rubiginosus) 		PF01261
(AP_endonuc_2) 		4 ARG A 321
ALA A 379
ASP A 273
SER A 333
 None
 0.96A 4ot2A-5y4jA:
undetectable		 4ot2A-5y4jA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus) 		no annotation 5 ARG A 209
ALA A 213
ASP A 324
LEU A 347
SER A 480
 None
 0.43A 4ot2A-5yxeA:
45.8		 4ot2A-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus) 		no annotation 4 ALA A 688
ASP A 685
LEU A 608
SER A 696
 None
 1.06A 4ot2A-6aunA:
2.5		 4ot2A-6aunA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aun PLA2G6, IPLA2BETA

(Cricetulus
griseus) 		no annotation 4 ARG A 705
ALA A 688
ASP A 685
LEU A 608
 None
 1.14A 4ot2A-6aunA:
2.5		 4ot2A-6aunA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b2w PUTATIVE
PEPTIDYL-ARGININE
DEIMINASE FAMILY
PROTEIN

(Campylobacter
jejuni) 		no annotation 4 ARG A 205
ALA A 213
ASP A 142
LEU A 289
 None
 1.15A 4ot2A-6b2wA:
undetectable		 4ot2A-6b2wA:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6h25 -

(-) 		no annotation 4 ARG A  27
ASP A  25
LEU A  50
SER A 195
 None
 1.15A 4ot2A-6h25A:
undetectable		 4ot2A-6h25A:
undetectable