SIMILAR PATTERNS OF AMINO ACIDS FOR 4OR0_A_NPSA602_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1akc | ASPARTATEAMINOTRANSFERASE (Gallus gallus) |
PF00155(Aminotran_1_2) | 5 | ALA A 190ALA A 239LEU A 208LEU A 252VAL A 250 | None | 1.13A | 4or0A-1akcA:0.0 | 4or0A-1akcA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1al8 | GLYCOLATE OXIDASE (Spinaciaoleracea) |
PF01070(FMN_dh) | 5 | ALA A 91ALA A 93SER A 314LEU A 315VAL A 311 | None | 1.20A | 4or0A-1al8A:undetectable | 4or0A-1al8A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c2y | PROTEIN (LUMAZINESYNTHASE) (Spinaciaoleracea) |
PF00885(DMRL_synthase) | 5 | ALA A 56ALA A 21LEU A 31SER A 97VAL A 100 | LMZ A 201 (-3.1A)LMZ A 201 ( 3.8A)NoneNoneNone | 1.28A | 4or0A-1c2yA:undetectable | 4or0A-1c2yA:13.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgs | DNA LIGASE (Thermusfiliformis) |
PF01653(DNA_ligase_aden)PF03120(DNA_ligase_OB)PF12826(HHH_2)PF14520(HHH_5) | 5 | ALA A 552ALA A 554LEU A 512SER A 537LEU A 538 | None | 1.37A | 4or0A-1dgsA:undetectable | 4or0A-1dgsA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e3d | [NIFE] HYDROGENASELARGE SUBUNIT (Desulfovibriodesulfuricans) |
PF00374(NiFeSe_Hases) | 5 | ALA B 132ALA B 135LEU B 143LEU B 164VAL B 160 | None | 1.30A | 4or0A-1e3dB:undetectable | 4or0A-1e3dB:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fc9 | PHOTOSYSTEM II D1PROTEASE (Tetradesmusobliquus) |
PF03572(Peptidase_S41)PF13180(PDZ_2) | 5 | ALA A 340ALA A 417LEU A 399LEU A 338VAL A 337 | None | 1.27A | 4or0A-1fc9A:1.1 | 4or0A-1fc9A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ggm | GLYCINE--TRNA LIGASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 5 | PHE A 298ALA A 373ALA A 375LEU A 369VAL A 368 | None | 1.34A | 4or0A-1ggmA:undetectable | 4or0A-1ggmA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gxn | PECTATE LYASE (Cellvibriojaponicus) |
PF09492(Pec_lyase) | 5 | ALA A 420ALA A 419LEU A 400LEU A 461VAL A 460 | None | 1.37A | 4or0A-1gxnA:undetectable | 4or0A-1gxnA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h5y | HISF (Pyrobaculumaerophilum) |
PF00977(His_biosynth) | 5 | ALA A 207LEU A 225SER A 236LEU A 235VAL A 240 | PO4 A 302 ( 4.9A)NoneNoneNoneNone | 1.13A | 4or0A-1h5yA:undetectable | 4or0A-1h5yA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hq0 | CYTOTOXICNECROTIZING FACTOR 1 (Escherichiacoli) |
PF05785(CNF1) | 5 | PHE A 758ALA A 760ALA A 761LEU A 904VAL A 833 | None | 1.34A | 4or0A-1hq0A:undetectable | 4or0A-1hq0A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hv6 | ALGINATE LYASE (Sphingomonassp.) |
PF05426(Alginate_lyase) | 5 | ALA A 146ALA A 149LEU A 97LEU A 171VAL A 167 | None | 1.27A | 4or0A-1hv6A:undetectable | 4or0A-1hv6A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j3n | 3-OXOACYL-(ACYL-CARRIER PROTEIN)SYNTHASE II (Thermusthermophilus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | PHE A 405ALA A 288SER A 391LEU A 403VAL A 402 | None | 1.32A | 4or0A-1j3nA:undetectable | 4or0A-1j3nA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqv | CYTOCHROME C' (Rhodopseudomonaspalustris) |
PF01322(Cytochrom_C_2) | 5 | ALA A 45ALA A 86LEU A 51SER A 40LEU A 41 | None | 1.35A | 4or0A-1mqvA:2.8 | 4or0A-1mqvA:12.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mxf | PTERIDINE REDUCTASE2 (Trypanosomacruzi) |
PF13561(adh_short_C2) | 5 | PHE A 251ALA A 248ALA A 246LEU A 252VAL A 253 | None | 1.20A | 4or0A-1mxfA:undetectable | 4or0A-1mxfA:18.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1naa | CELLOBIOSEDEHYDROGENASE (Phanerochaetechrysosporium) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | ALA A 745ALA A 741LEU A 341SER A 236LEU A 235 | None | 1.34A | 4or0A-1naaA:undetectable | 4or0A-1naaA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvm | 4-HYDROXY-2-OXOVALERATE ALDOLASE (Pseudomonas sp.CF600) |
PF00682(HMGL-like)PF07836(DmpG_comm) | 5 | ALA A 246ALA A 244LEU A 260SER A 212VAL A 209 | None | 1.29A | 4or0A-1nvmA:undetectable | 4or0A-1nvmA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rhy | IMIDAZOLE GLYCEROLPHOSPHATEDEHYDRATASE (Cryptococcusneoformans) |
PF00475(IGPD) | 5 | PHE A 122ALA A 149ALA A 151SER A 142LEU A 145 | EMC A5501 (-4.3A)NoneNoneNoneNone | 1.28A | 4or0A-1rhyA:undetectable | 4or0A-1rhyA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t98 | CHROMOSOME PARTITIONPROTEIN MUKF (Escherichiacoli) |
PF03882(KicB)PF17192(MukF_M) | 5 | ALA A 143ALA A 139LEU A 136LEU A 246VAL A 249 | None | 1.30A | 4or0A-1t98A:2.4 | 4or0A-1t98A:18.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 7 | ARG A 209ALA A 210ALA A 213LEU A 327SER A 480LEU A 481VAL A 482 | DKA A1001 ( 4.6A)DKA A1002 (-3.3A)DKA A1001 ( 4.0A)DKA A1001 (-4.1A)DKA A1002 (-3.4A)NoneDKA A1002 (-4.2A) | 0.70A | 4or0A-1tf0A:45.0 | 4or0A-1tf0A:76.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 7 | ARG A 209ALA A 210LEU A 327LYS A 351SER A 480LEU A 481VAL A 482 | DKA A1001 ( 4.6A)DKA A1002 (-3.3A)DKA A1001 (-4.1A)DKA A1002 (-2.6A)DKA A1002 (-3.4A)NoneDKA A1002 (-4.2A) | 0.93A | 4or0A-1tf0A:45.0 | 4or0A-1tf0A:76.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | PHE A 206ALA A 210ALA A 213SER A 480LEU A 481VAL A 482 | NoneDKA A1002 (-3.3A)DKA A1001 ( 4.0A)DKA A1002 (-3.4A)NoneDKA A1002 (-4.2A) | 0.85A | 4or0A-1tf0A:45.0 | 4or0A-1tf0A:76.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xty | PEPTIDYL-TRNAHYDROLASE (Sulfolobussolfataricus) |
PF01981(PTH2) | 5 | ALA A 26ALA A 24SER A 33LEU A 30VAL A 31 | None | 1.38A | 4or0A-1xtyA:undetectable | 4or0A-1xtyA:11.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yp1 | FII (Deinagkistrodonacutus) |
PF01421(Reprolysin) | 5 | PHE A 112ALA A 123ALA A 95SER A 76LEU A 75 | None | 1.24A | 4or0A-1yp1A:undetectable | 4or0A-1yp1A:14.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwp | 5-AMINOLEVULINATESYNTHASE (Rhodobactercapsulatus) |
PF00155(Aminotran_1_2) | 5 | ALA A 285ALA A 286LEU A 73LEU A 246VAL A 252 | None | 1.11A | 4or0A-2bwpA:undetectable | 4or0A-2bwpA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gqd | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Staphylococcusaureus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | PHE A 409ALA A 291SER A 395LEU A 407VAL A 406 | None | 1.17A | 4or0A-2gqdA:undetectable | 4or0A-2gqdA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hdx | SH2-B PH DOMAINCONTAINING SIGNALINGMEDIATOR 1 GAMMAISOFORM (Mus musculus) |
PF00017(SH2) | 5 | PHE A 568ALA A 537LEU A 535LEU A 566VAL A 565 | None | 1.17A | 4or0A-2hdxA:undetectable | 4or0A-2hdxA:9.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iyo | 6-PHOSPHOGLUCONATEDEHYDROGENASE,DECARBOXYLATING (Lactococcuslactis) |
PF00393(6PGD)PF03446(NAD_binding_2) | 5 | PHE A 156ALA A 160ALA A 161LEU A 136VAL A 127 | None | 1.27A | 4or0A-2iyoA:undetectable | 4or0A-2iyoA:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jbh | PHOSPHORIBOSYLTRANSFERASEDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00156(Pribosyltran) | 5 | PHE A 81ALA A 199SER A 169LEU A 170VAL A 143 | CAS A 82 ( 4.7A)NoneNoneNone5GP A1230 (-4.0A) | 1.11A | 4or0A-2jbhA:undetectable | 4or0A-2jbhA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kq9 | DNAK SUPPRESSORPROTEIN (Agrobacteriumfabrum) |
PF01258(zf-dskA_traR) | 5 | ALA A 72ALA A 68LEU A 66LEU A 96VAL A 99 | None | 1.37A | 4or0A-2kq9A:undetectable | 4or0A-2kq9A:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph3 | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 5 | PHE A 222ALA A 219ALA A 217LEU A 223VAL A 224 | None | 1.19A | 4or0A-2ph3A:undetectable | 4or0A-2ph3A:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ppv | UNCHARACTERIZEDPROTEIN (Staphylococcusepidermidis) |
PF01933(UPF0052) | 5 | PHE A 75ALA A 62ALA A 63LEU A 15LEU A 115 | None | 1.32A | 4or0A-2ppvA:undetectable | 4or0A-2ppvA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7d | RIBONUCLEASE IIFAMILY PROTEIN (Deinococcusradiodurans) |
PF00773(RNB) | 5 | ALA A 39ALA A 42SER A 25LEU A 17VAL A 14 | None | 1.06A | 4or0A-2r7dA:undetectable | 4or0A-2r7dA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhl | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 5 | ALA A 198ALA A 218LEU A 210SER A 156LEU A 187 | None | 1.17A | 4or0A-2vhlA:undetectable | 4or0A-2vhlA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk2 | ABC TRANSPORTERPERIPLASMIC-BINDINGPROTEIN YTFQ (Escherichiacoli) |
PF13407(Peripla_BP_4) | 5 | ALA A 252ALA A 255LEU A 88LEU A 35VAL A 5 | None | 1.38A | 4or0A-2vk2A:undetectable | 4or0A-2vk2A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wae | PENICILLIN-BINDINGPROTEIN 2B (Streptococcuspneumoniae) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | PHE A 316ALA A 66LEU A 71LEU A 356VAL A 355 | None | 1.34A | 4or0A-2waeA:undetectable | 4or0A-2waeA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fhl | PUTATIVEOXIDOREDUCTASE (Bacteroidesfragilis) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | ALA A 80ALA A 83LEU A 58SER A 118LEU A 117 | None | 1.12A | 4or0A-3fhlA:undetectable | 4or0A-3fhlA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h75 | PERIPLASMICSUGAR-BINDING DOMAINPROTEIN (Pseudomonasprotegens) |
PF13407(Peripla_BP_4) | 5 | ALA A 253ALA A 256LEU A 185SER A 292LEU A 291 | None | 1.25A | 4or0A-3h75A:undetectable | 4or0A-3h75A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kr9 | SAM-DEPENDENTMETHYLTRANSFERASE (Streptococcuspneumoniae) |
PF04816(TrmK) | 5 | PHE A 79ARG A 71ALA A 78ALA A 73LEU A 76 | None | 1.39A | 4or0A-3kr9A:undetectable | 4or0A-3kr9A:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lmo | SPECIALIZED ACYLCARRIER PROTEIN (Rhodopseudomonaspalustris) |
PF00550(PP-binding) | 5 | PHE A 5ALA A 81ALA A 82LEU A 77VAL A 76 | None | 1.18A | 4or0A-3lmoA:undetectable | 4or0A-3lmoA:10.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbk | FATTY ACYL-ADENYLATELIGASE (Escherichiacoli) |
PF00501(AMP-binding) | 5 | ALA A 59ALA A 63LEU A 99LEU A 27VAL A 24 | None | 1.37A | 4or0A-3pbkA:undetectable | 4or0A-3pbkA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pbk | FATTY ACYL-ADENYLATELIGASE (Escherichiacoli) |
PF00501(AMP-binding) | 5 | PHE A 92ALA A 59ALA A 63LEU A 27VAL A 24 | None | 1.27A | 4or0A-3pbkA:undetectable | 4or0A-3pbkA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r2j | ALPHA/BETA-HYDROLASE-LIKE PROTEIN (Leishmaniainfantum) |
PF00857(Isochorismatase) | 5 | ALA A 166ALA A 169LEU A 143LEU A 178VAL A 177 | None | 1.37A | 4or0A-3r2jA:undetectable | 4or0A-3r2jA:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9s | CARNITINYL-COADEHYDRATASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | PHE A 63ALA A 128ALA A 170LEU A 168VAL A 122 | None | 1.36A | 4or0A-3r9sA:undetectable | 4or0A-3r9sA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rc0 | N-LYSINEMETHYLTRANSFERASESETD6 (Homo sapiens) |
PF00856(SET)PF09273(Rubis-subs-bind) | 5 | ALA A 271ALA A 258LEU A 260SER A 37VAL A 64 | None | 1.27A | 4or0A-3rc0A:undetectable | 4or0A-3rc0A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s7w | EIGHT-HEME NITRITEREDUCTASE (Thioalkalivibrionitratireducens) |
PF02335(Cytochrom_C552) | 5 | PHE A 452ALA A 455ALA A 458LEU A 465VAL A 464 | None | 1.20A | 4or0A-3s7wA:2.1 | 4or0A-3s7wA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttb | EIGHT-HEME NITRITEREDUCTASE (Thioalkalivibrioparadoxus) |
PF02335(Cytochrom_C552) | 5 | PHE A 452ALA A 455ALA A 458LEU A 465VAL A 464 | None | 1.22A | 4or0A-3ttbA:undetectable | 4or0A-3ttbA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zpj | TON_1535 (Thermococcusonnurineus) |
no annotation | 5 | PHE A 97ALA A 100ALA A 74LEU A 67SER A 82 | None | 1.29A | 4or0A-3zpjA:undetectable | 4or0A-3zpjA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 5 | PHE A 459ALA A 383ALA A 405SER A 336LEU A 335 | None | 1.13A | 4or0A-4a5qA:undetectable | 4or0A-4a5qA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bms | ALCLOHOLDEHYDROGENASE/SHORT-CHAIN DEHYDROGENASE (Ralstonia sp.DSMZ 6428) |
PF13561(adh_short_C2) | 5 | PHE A 226ALA A 223ALA A 221SER A 232LEU A 227 | None | 1.34A | 4or0A-4bmsA:undetectable | 4or0A-4bmsA:17.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3y | DIHYDRODIPICOLINATEREDUCTASE (Burkholderiathailandensis) |
PF01113(DapB_N)PF05173(DapB_C) | 5 | ALA A 47ALA A 11LEU A 35LEU A 24VAL A 23 | None | 1.18A | 4or0A-4f3yA:undetectable | 4or0A-4f3yA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fgs | PROBABLEDEHYDROGENASEPROTEIN (Rhizobium etli) |
PF13561(adh_short_C2) | 5 | PHE A 228ALA A 225ALA A 223SER A 234LEU A 229 | None | 1.35A | 4or0A-4fgsA:undetectable | 4or0A-4fgsA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gtu | GLUTATHIONES-TRANSFERASE (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | PHE A 157ALA A 15ALA A 13LEU A 203LEU A 19 | None | 1.24A | 4or0A-4gtuA:undetectable | 4or0A-4gtuA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h1x | PHOSPHATE-BINDINGPROTEIN PSTS 2 (Streptococcuspneumoniae) |
PF12849(PBP_like_2) | 5 | PHE A 165ALA A 254ALA A 252LEU A 195VAL A 192 | None | 0.88A | 4or0A-4h1xA:undetectable | 4or0A-4h1xA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hht | RIBONUCLEASE HII (Thermotogamaritima) |
PF01351(RNase_HII) | 5 | ALA A 32ALA A 93LEU A 113SER A 21VAL A 29 | NoneNoneNone C D 6 ( 4.7A)None | 1.35A | 4or0A-4hhtA:undetectable | 4or0A-4hhtA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4id7 | ACTIVATED CDC42KINASE 1 (Homo sapiens) |
PF07714(Pkinase_Tyr) | 5 | PHE A 324ALA A 255LEU A 253SER A 230LEU A 229 | None | 1.35A | 4or0A-4id7A:undetectable | 4or0A-4id7A:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kf8 | NUP188 (Thermothelomycesthermophila) |
no annotation | 5 | ALA A1660ALA A1657LEU A1785SER A1695LEU A1692 | None | 1.37A | 4or0A-4kf8A:undetectable | 4or0A-4kf8A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kms | ACETOACETYL-COAREDUCTASE (Rickettsiafelis) |
PF13561(adh_short_C2) | 5 | PHE A 218ALA A 215ALA A 213LEU A 219VAL A 220 | None | 1.21A | 4or0A-4kmsA:undetectable | 4or0A-4kmsA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpu | ELECTRON TRANSFERFLAVOPROTEINALPHA/BETA-SUBUNIT (Acidaminococcusfermentans) |
PF01012(ETF) | 5 | PHE B 239ALA B 247ALA B 245LEU B 251VAL B 252 | None | 1.13A | 4or0A-4kpuB:undetectable | 4or0A-4kpuB:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l7m | PUTATIVEUNCHARACTERIZEDPROTEIN (Thermococcusonnurineus) |
PF13646(HEAT_2) | 5 | ALA A 117ALA A 116SER A 140LEU A 139VAL A 138 | None | 1.08A | 4or0A-4l7mA:2.6 | 4or0A-4l7mA:18.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | ALA A 210ALA A 213LYS A 351SER A 480LEU A 481VAL A 482 | NoneNPS A 602 (-3.3A)NoneNoneNoneNone | 0.84A | 4or0A-4po0A:50.1 | 4or0A-4po0A:71.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | ALA A 213LEU A 327LYS A 351SER A 480LEU A 481VAL A 482 | NPS A 602 (-3.3A)NPS A 602 ( 4.7A)NoneNoneNoneNone | 0.76A | 4or0A-4po0A:50.1 | 4or0A-4po0A:71.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | ARG A 209ALA A 210ALA A 213SER A 480LEU A 481VAL A 482 | NPS A 602 (-3.6A)NoneNPS A 602 (-3.3A)NoneNoneNone | 0.82A | 4or0A-4po0A:50.1 | 4or0A-4po0A:71.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | ARG A 209ALA A 213LEU A 327SER A 480LEU A 481VAL A 482 | NPS A 602 (-3.6A)NPS A 602 (-3.3A)NPS A 602 ( 4.7A)NoneNoneNone | 1.02A | 4or0A-4po0A:50.1 | 4or0A-4po0A:71.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | PHE A 206ALA A 210ALA A 213SER A 480LEU A 481VAL A 482 | NoneNoneNPS A 602 (-3.3A)NoneNoneNone | 0.68A | 4or0A-4po0A:50.1 | 4or0A-4po0A:71.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxt | SUGAR ABCTRANSPORTER (Agrobacteriumtumefaciens) |
PF13407(Peripla_BP_4) | 5 | ALA A 235ALA A 229LEU A 177LEU A 274VAL A 275 | NoneNoneARA A 401 ( 4.6A)NoneNone | 1.32A | 4or0A-4rxtA:undetectable | 4or0A-4rxtA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u48 | PUTATIVE INNERMEMBRANE LIPOPROTEIN (Salmonellaenterica) |
PF00207(A2M)PF01835(A2M_N)PF07703(A2M_N_2)PF10569(Thiol-ester_cl)PF11974(MG1) | 5 | ALA A1421ALA A1425LEU A1386SER A1376LEU A1377 | None | 1.37A | 4or0A-4u48A:2.7 | 4or0A-4u48A:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udr | GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE (Methylovorussp. MP688) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | ALA A 524ALA A 520LEU A 517SER A 25LEU A 24 | None | 1.24A | 4or0A-4udrA:undetectable | 4or0A-4udrA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wcd | PTERIDINE REDUCTASE (Trypanosomabrucei) |
PF13561(adh_short_C2) | 5 | PHE A 243ALA A 240ALA A 238LEU A 244VAL A 245 | None | 1.15A | 4or0A-4wcdA:undetectable | 4or0A-4wcdA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y1p | 3-ISOPROPYLMALATEDEHYDROGENASE (Sulfolobusacidocaldarius) |
PF00180(Iso_dh) | 5 | ALA A 98ALA A 235LEU A 101SER A 243VAL A 256 | None | 1.37A | 4or0A-4y1pA:undetectable | 4or0A-4y1pA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5l | D-FRUCTOSE1,6-BISPHOSPHATASECLASS2/SEDOHEPTULOSE1,7-BISPHOSPHATASE (Thermosynechococcuselongatus) |
PF03320(FBPase_glpX) | 5 | ALA A 232ALA A 231LEU A 285LEU A 205VAL A 201 | None | 1.17A | 4or0A-5a5lA:undetectable | 4or0A-5a5lA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3h | PROTEIN SCARECROW (Arabidopsisthaliana) |
PF03514(GRAS) | 5 | ALA A 298ALA A 300LEU A 306SER A 529LEU A 531 | None | 1.34A | 4or0A-5b3hA:2.7 | 4or0A-5b3hA:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dmx | D-ALANINE--D-ALANINELIGASE (Acinetobacterbaumannii) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | ALA A 30ALA A 34LEU A 295SER A 24VAL A 64 | None | 1.38A | 4or0A-5dmxA:undetectable | 4or0A-5dmxA:19.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | ALA A 209ALA A 212LEU A 326SER A 479LEU A 480 | CZE A 613 ( 4.4A)CZE A 613 ( 3.7A)CZE A 613 ( 4.7A)NoneNone | 1.02A | 4or0A-5dqfA:50.6 | 4or0A-5dqfA:73.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | ALA A 209LEU A 326LYS A 350SER A 479LEU A 480 | CZE A 613 ( 4.4A)CZE A 613 ( 4.7A)CZE A 613 (-4.1A)NoneNone | 1.13A | 4or0A-5dqfA:50.6 | 4or0A-5dqfA:73.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | PHE A 205ALA A 209ALA A 212SER A 479LEU A 480 | NoneCZE A 613 ( 4.4A)CZE A 613 ( 3.7A)NoneNone | 0.89A | 4or0A-5dqfA:50.6 | 4or0A-5dqfA:73.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | PHE A 205ARG A 208ALA A 209ALA A 212LEU A 480 | NoneCZE A 613 ( 3.5A)CZE A 613 ( 4.4A)CZE A 613 ( 3.7A)None | 0.90A | 4or0A-5dqfA:50.6 | 4or0A-5dqfA:73.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5epv | BLUE-LIGHT-ACTIVATEDHISTIDINE KINASE (Brucellaabortus) |
PF07536(HWE_HK) | 5 | ALA A 394ALA A 389LEU A 385SER A 461VAL A 429 | NoneACP A 501 ( 4.4A)NoneNoneACP A 501 ( 4.2A) | 1.31A | 4or0A-5epvA:2.1 | 4or0A-5epvA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5exk | LIPOYL SYNTHASE (Mycobacteriumtuberculosis) |
PF04055(Radical_SAM)PF16881(LIAS_N) | 5 | ALA A 210ALA A 206LEU A 204SER A 172VAL A 169 | None | 1.07A | 4or0A-5exkA:undetectable | 4or0A-5exkA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f0o | COHESIN SUBUNITPDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P,KLTH0D07062P,COHESIN SUBUNIT PDS5,KLTH0D07062P,KLTH0D07062P (Lachanceathermotolerans) |
no annotation | 5 | PHE A 417ALA A 456ALA A 458LEU A 438VAL A 439 | None | 1.39A | 4or0A-5f0oA:2.1 | 4or0A-5f0oA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fby | SEPARASE (Chaetomiumthermophilum) |
PF03568(Peptidase_C50) | 5 | ALA A2137LEU A1988SER A2184LEU A2185VAL A2186 | None | 0.89A | 4or0A-5fbyA:undetectable | 4or0A-5fbyA:22.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | ALA A 210ALA A 213LEU A 327LEU A 481VAL A 482 | None | 0.87A | 4or0A-5ghkA:46.8 | 4or0A-5ghkA:76.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | PHE A 206ALA A 210ALA A 213LEU A 481VAL A 482 | None | 0.98A | 4or0A-5ghkA:46.8 | 4or0A-5ghkA:76.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gjv | VOLTAGE-DEPENDENTL-TYPE CALCIUMCHANNEL SUBUNITALPHA-1S (Oryctolaguscuniculus) |
PF00520(Ion_trans)PF08763(Ca_chan_IQ)PF16905(GPHH) | 5 | ALA A 660LEU A 562SER A 334LEU A 333VAL A 332 | None | 1.20A | 4or0A-5gjvA:undetectable | 4or0A-5gjvA:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijg | CYS/MET METABOLISMPYRIDOXAL-PHOSPHATE-DEPENDENT ENZYME (Brucellamelitensis) |
PF01053(Cys_Met_Meta_PP) | 5 | ALA A 253ALA A 110LYS A 265SER A 100LEU A 255 | None | 1.14A | 4or0A-5ijgA:undetectable | 4or0A-5ijgA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ijz | NADP-SPECIFICGLUTAMATEDEHYDROGENASE (Corynebacteriumglutamicum) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | PHE A 262ALA A 245ALA A 248LEU A 280VAL A 277 | None | 1.27A | 4or0A-5ijzA:undetectable | 4or0A-5ijzA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldn | HEXON PROTEIN,HEXONCAPSID (HumanmastadenovirusC) |
PF01065(Adeno_hexon)PF03678(Adeno_hexon_C) | 5 | ARG A 32ALA A 31ALA A 33SER A 24LEU A 27 | None | 1.19A | 4or0A-5ldnA:undetectable | 4or0A-5ldnA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkk | MULTIDRUG RESISTANCEABC TRANSPORTERATP-BINDING ANDPERMEASE PROTEIN (Thermusthermophilus) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | ALA A 390ALA A 553LEU A 556LEU A 566VAL A 567 | None | 1.16A | 4or0A-5mkkA:3.4 | 4or0A-5mkkA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nux | CHROMATE REDUCTASE (Thermusscotoductus) |
no annotation | 5 | PHE A 154ALA A 158ALA A 161LEU A 83LEU A 171 | None | 1.31A | 4or0A-5nuxA:undetectable | 4or0A-5nuxA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojs | TRANSCRIPTION-ASSOCIATED PROTEIN 1 (Saccharomycescerevisiae) |
PF00454(PI3_PI4_kinase)PF02259(FAT) | 5 | ALA T1148ALA T1152LEU T1200SER T1143LEU T1144 | None | 1.39A | 4or0A-5ojsT:undetectable | 4or0A-5ojsT:9.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 7 | PHE A 205ARG A 208ALA A 209ALA A 212LEU A 326LEU A 480VAL A 481 | None | 0.74A | 4or0A-5oriA:52.3 | 4or0A-5oriA:91.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 7 | PHE A 205ARG A 208ALA A 209LEU A 326SER A 479LEU A 480VAL A 481 | None | 0.97A | 4or0A-5oriA:52.3 | 4or0A-5oriA:91.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xon | TRANSCRIPTIONELONGATION FACTORSPT4 (Komagataellaphaffii) |
PF06093(Spt4) | 5 | ALA V 83ALA V 11LEU V 19LEU V 72VAL V 74 | None | 1.35A | 4or0A-5xonV:undetectable | 4or0A-5xonV:12.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 7 | PHE A 206ARG A 209ALA A 210ALA A 213LEU A 327LEU A 481VAL A 482 | None | 0.80A | 4or0A-5yxeA:44.5 | 4or0A-5yxeA:78.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 5 | PHE A 206LEU A 327SER A 480LEU A 481VAL A 482 | None | 1.10A | 4or0A-5yxeA:44.5 | 4or0A-5yxeA:78.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zal | ENDORIBONUCLEASEDICER (Homo sapiens) |
no annotation | 5 | PHE A1812ALA A1816ALA A1818LEU A1683VAL A1833 | None | 1.36A | 4or0A-5zalA:2.7 | 4or0A-5zalA:9.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bql | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 2 (Homo sapiens) |
no annotation | 5 | PHE A 267ALA A 192ALA A 182LEU A 162VAL A 252 | BI9 A 501 ( 4.2A)BI9 A 501 (-3.3A)NoneNoneNone | 1.31A | 4or0A-6bqlA:2.5 | 4or0A-6bqlA:9.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byo | VOLTAGE-DEPENDENTL-TYPE CALCIUMCHANNEL SUBUNITALPHA-1S (Oryctolaguscuniculus) |
no annotation | 5 | ALA A 660ALA A 658SER A 334LEU A 333VAL A 332 | None | 1.24A | 4or0A-6byoA:undetectable | 4or0A-6byoA:8.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6byo | VOLTAGE-DEPENDENTL-TYPE CALCIUMCHANNEL SUBUNITALPHA-1S (Oryctolaguscuniculus) |
no annotation | 5 | ALA A 660LEU A 562SER A 334LEU A 333VAL A 332 | None | 1.16A | 4or0A-6byoA:undetectable | 4or0A-6byoA:8.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cg0 | V(D)JRECOMBINATION-ACTIVATING PROTEIN 1 (Mus musculus) |
no annotation | 5 | PHE A 622ALA A 554LEU A 659SER A 623LEU A 655 | None | 1.27A | 4or0A-6cg0A:2.8 | 4or0A-6cg0A:9.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cmj | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 2 (Homo sapiens) |
no annotation | 5 | PHE A 267ALA A 192ALA A 182LEU A 162VAL A 252 | F6J A 501 (-3.7A)F6J A 501 (-3.4A)NoneNoneNone | 1.38A | 4or0A-6cmjA:2.4 | 4or0A-6cmjA:9.20 |