SIMILAR PATTERNS OF AMINO ACIDS FOR 4OLM_A_198A1001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b63 MUTL

(Escherichia
coli) 		PF01119
(DNA_mis_repair)
PF13589
(HATPase_c_3) 		4 MET A 263
ILE A 187
ILE A  42
VAL A 185
 None
 0.96A 4olmA-1b63A:
undetectable		 4olmA-1b63A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cyg CYCLODEXTRIN
GLUCANOTRANSFERASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 MET A 230
ILE A 219
ILE A 215
VAL A 248
 None
 0.95A 4olmA-1cygA:
0.0		 4olmA-1cygA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f2n CAPSID PROTEIN

(Rice yellow
mottle virus) 		PF00729
(Viral_coat) 		4 ASN A  84
ILE A 198
ILE A 186
VAL A 195
 None
 0.96A 4olmA-1f2nA:
0.0		 4olmA-1f2nA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 ASN A 103
ILE A  91
ILE A  92
VAL A  76
 None
 0.97A 4olmA-1fcpA:
undetectable		 4olmA-1fcpA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fiu TYPE II RESTRICTION
ENZYME NGOMI

(Neisseria
gonorrhoeae) 		PF09015
(NgoMIV_restric) 		4 ASN A 197
ILE A 238
ILE A 231
VAL A 241
 ACY  A2001 (-3.6A)
None
None
None
 0.95A 4olmA-1fiuA:
0.0		 4olmA-1fiuA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g29 MALTOSE TRANSPORT
PROTEIN MALK

(Thermococcus
litoralis) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		4 MET 1 213
ILE 1  62
ILE 1  83
VAL 1 160
 None
 0.94A 4olmA-1g291:
0.0		 4olmA-1g291:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gns SUBTILISIN BPN'

(Bacillus
amyloliquefaciens) 		PF00082
(Peptidase_S8) 		4 MET A 119
ILE A 268
ILE A  11
VAL A 270
 None
 0.90A 4olmA-1gnsA:
0.0		 4olmA-1gnsA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1scj SUBTILISIN E

(Bacillus
subtilis) 		PF00082
(Peptidase_S8) 		4 MET A 119
ILE A 268
ILE A  11
VAL A 270
 None
 1.00A 4olmA-1scjA:
0.0		 4olmA-1scjA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1siv SIV PROTEASE

(Simian
immunodeficiency
virus) 		PF00077
(RVP) 		4 ASN A  83
ILE A  64
ILE A  15
VAL A  62
 None
 0.86A 4olmA-1sivA:
undetectable		 4olmA-1sivA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sq5 PANTOTHENATE KINASE

(Escherichia
coli) 		PF00485
(PRK) 		4 MET A1029
ILE A1197
ILE A1195
VAL A1121
 None
 0.88A 4olmA-1sq5A:
0.0		 4olmA-1sq5A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdf THIOREDOXIN
REDUCTASE

(Escherichia
coli) 		PF07992
(Pyr_redox_2) 		4 ASN A 100
ILE A  34
ILE A  80
VAL A  32
 None
 0.90A 4olmA-1tdfA:
undetectable		 4olmA-1tdfA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ud9 DNA POLYMERASE
SLIDING CLAMP A

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 ASN A 106
ILE A  87
ILE A  88
VAL A   4
 None
 0.96A 4olmA-1ud9A:
undetectable		 4olmA-1ud9A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wc5 ADENYLATE CYCLASE

(Arthrospira
platensis) 		PF00211
(Guanylate_cyc) 		4 MET A1073
ILE A1160
ILE A1195
VAL A1162
 None
 0.85A 4olmA-1wc5A:
undetectable		 4olmA-1wc5A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x4g NUCLEOLYSIN TIAR

(Homo sapiens) 		PF00076
(RRM_1) 		4 MET A  53
ILE A  33
ILE A  86
VAL A  91
 None
 0.90A 4olmA-1x4gA:
undetectable		 4olmA-1x4gA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yew PARTICULATE METHANE
MONOOXYGENASE, A
SUBUNIT
PARTICULATE METHANE
MONOOXYGENASE, B
SUBUNIT

(Methylococcus
capsulatus) 		PF02461
(AMO)
PF04744
(Monooxygenase_B) 		4 ASN A 168
ILE B 180
ILE B 183
VAL B 171
 None
 0.95A 4olmA-1yewA:
undetectable		 4olmA-1yewA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z45 GAL10 BIFUNCTIONAL
PROTEIN

(Saccharomyces
cerevisiae) 		PF01263
(Aldose_epim)
PF16363
(GDP_Man_Dehyd) 		4 ASN A 457
ILE A 570
ILE A 670
VAL A 565
 GAL  A 700 (-3.6A)
None
None
None
 1.02A 4olmA-1z45A:
undetectable		 4olmA-1z45A:
18.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		6 ASN A 705
MET A 749
MET A 787
ILE A 898
ILE A 899
VAL A 903
 BHM  A   1 (-3.6A)
BHM  A   1 (-4.3A)
BHM  A   1 (-3.6A)
None
None
None
 0.59A 4olmA-2ax9A:
40.0		 4olmA-2ax9A:
99.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw6 BLL6730 PROTEIN

(Bradyrhizobium
japonicum) 		PF13378
(MR_MLE_C) 		4 ASN A 330
MET A 384
ILE A 364
VAL A 357
 None
 1.01A 4olmA-2dw6A:
undetectable		 4olmA-2dw6A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iy8 PROTEIN PM0188

(Pasteurella
multocida) 		PF11477
(PM0188) 		4 ASN A  50
MET A 342
ILE A  66
ILE A  70
 None
 0.99A 4olmA-2iy8A:
undetectable		 4olmA-2iy8A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmo SER/THR PROTEIN
KINASE

(Plasmodium
falciparum) 		PF00069
(Pkinase) 		4 MET X 120
ILE X 107
ILE X 106
VAL X 113
 None
 1.00A 4olmA-2pmoX:
undetectable		 4olmA-2pmoX:
19.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q3y ANCESTRAL CORTICIOD
RECEPTOR

(unidentified) 		PF00104
(Hormone_recep) 		4 ASN A  33
MET A 115
ILE A 226
ILE A 227
 1CA  A 247 (-2.9A)
1CA  A 247 ( 3.7A)
None
None
 0.79A 4olmA-2q3yA:
36.4		 4olmA-2q3yA:
59.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rc5 FERREDOXIN-NADP
REDUCTASE

(Leptospira
interrogans) 		PF00175
(NAD_binding_1) 		4 MET A 183
ILE A 283
ILE A 286
VAL A 282
 None
 0.91A 4olmA-2rc5A:
undetectable		 4olmA-2rc5A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6e PROTELEMORASE

(Klebsiella
phage phiKO2) 		PF16684
(Telomere_res) 		4 MET A 276
ILE A 233
ILE A 531
VAL A 231
 None
 0.69A 4olmA-2v6eA:
undetectable		 4olmA-2v6eA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE

(Staphylococcus
aureus) 		PF00155
(Aminotran_1_2) 		4 ASN A 156
MET A  30
ILE A 190
VAL A 229
 None
 0.96A 4olmA-2x5fA:
undetectable		 4olmA-2x5fA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		4 ASN A 365
MET A 375
ILE A 486
VAL A 485
 None
 0.96A 4olmA-2xijA:
undetectable		 4olmA-2xijA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xsg CCMAN5

(Cellulosimicrobium
cellulans) 		PF07971
(Glyco_hydro_92) 		4 MET A 655
ILE A 363
ILE A 366
VAL A 362
 None
 0.89A 4olmA-2xsgA:
undetectable		 4olmA-2xsgA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6i TRANS-2-ENOYL-ACP
REDUCTASE II

(Streptococcus
pneumoniae) 		PF03060
(NMO) 		4 MET A 103
ILE A  55
ILE A  41
VAL A  51
 None
 0.99A 4olmA-2z6iA:
undetectable		 4olmA-2z6iA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbk TYPE 2 DNA
TOPOISOMERASE 6
SUBUNIT B

(Sulfolobus
shibatae) 		PF02518
(HATPase_c)
PF09239
(Topo-VIb_trans) 		4 MET B 107
ILE B  56
ILE B  58
VAL B  74
 None
 0.88A 4olmA-2zbkB:
undetectable		 4olmA-2zbkB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a9g PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrobaculum
aerophilum) 		PF07995
(GSDH) 		4 MET A 228
ILE A 146
ILE A 143
VAL A 124
 None
 0.95A 4olmA-3a9gA:
undetectable		 4olmA-3a9gA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bin BAND 4.1-LIKE
PROTEIN 3

(Homo sapiens) 		PF00373
(FERM_M)
PF09379
(FERM_N)
PF09380
(FERM_C) 		4 MET A 295
ILE A 340
ILE A 349
VAL A 337
 None
 0.98A 4olmA-3binA:
undetectable		 4olmA-3binA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4r DOMAIN OF UNKNOWN
FUNCTION FROM THE
PFAM-B_34464 FAMILY

(Methanococcus
maripaludis) 		PF09891
(DUF2118) 		4 MET A  55
ILE A  20
ILE A  27
VAL A  18
 None
 0.99A 4olmA-3d4rA:
undetectable		 4olmA-3d4rA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e74 ALLANTOINASE

(Escherichia
coli) 		PF01979
(Amidohydro_1) 		4 MET A 364
MET A 342
ILE A  30
ILE A  23
 None
 0.99A 4olmA-3e74A:
undetectable		 4olmA-3e74A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fyd PROBABLE
DIMETHYLADENOSINE
TRANSFERASE

(Methanocaldococcus
jannaschii) 		PF00398
(RrnaAD) 		4 ASN A  69
ILE A  78
ILE A  80
VAL A  57
 None
 1.00A 4olmA-3fydA:
undetectable		 4olmA-3fydA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gjy SPERMIDINE SYNTHASE

(Corynebacterium
glutamicum) 		no annotation 4 ASN A 113
ILE A 160
ILE A 161
VAL A 194
 None
 0.94A 4olmA-3gjyA:
undetectable		 4olmA-3gjyA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gpv TRANSCRIPTIONAL
REGULATOR, MERR
FAMILY

(Bacillus
thuringiensis) 		PF13411
(MerR_1) 		4 MET A  92
ILE A  24
ILE A  38
VAL A  27
 None
 0.97A 4olmA-3gpvA:
undetectable		 4olmA-3gpvA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hdy UDP-GALACTOPYRANOSE
MUTASE

(Deinococcus
radiodurans) 		PF03275
(GLF)
PF13450
(NAD_binding_8) 		4 ASN A 228
MET A 373
ILE A 235
VAL A 237
 None
FAD  A 450 (-4.4A)
None
None
 0.79A 4olmA-3hdyA:
undetectable		 4olmA-3hdyA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j47 26S PROTEASOME
REGULATORY SUBUNIT
RPN6
26S PROTEASOME
REGULATORY SUBUNIT
RPN8

(Saccharomyces
cerevisiae) 		PF13012
(MitMem_reg)
no annotation 		4 ASN Q 420
ILE U 286
ILE U 285
VAL U 282
 None
 0.93A 4olmA-3j47Q:
undetectable		 4olmA-3j47Q:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzp PUTATIVE DIGUANYLATE
CYCLASE/PHOSPHODIEST
ERASE

(Listeria
monocytogenes) 		PF00563
(EAL) 		4 ASN A 198
ILE A 146
ILE A 169
VAL A 149
 None
 1.00A 4olmA-3kzpA:
undetectable		 4olmA-3kzpA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldh LACTATE
DEHYDROGENASE

(Squalus
acanthias) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 MET A 274
ILE A  96
ILE A 127
VAL A  94
 None
 1.02A 4olmA-3ldhA:
undetectable		 4olmA-3ldhA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3na6 SUCCINYLGLUTAMATE
DESUCCINYLASE/ASPART
OACYLASE

(Ruegeria sp.
TM1040) 		PF04952
(AstE_AspA) 		4 MET A 201
ILE A  38
ILE A  40
VAL A  87
 None
 1.00A 4olmA-3na6A:
undetectable		 4olmA-3na6A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3of1 CAMP-DEPENDENT
PROTEIN KINASE
REGULATORY SUBUNIT

(Saccharomyces
cerevisiae) 		PF00027
(cNMP_binding) 		4 MET A 300
ILE A 330
ILE A 329
VAL A 381
 None
CMP  A 601 (-4.8A)
None
None
 1.01A 4olmA-3of1A:
undetectable		 4olmA-3of1A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qk9 MITOCHONDRIAL IMPORT
INNER MEMBRANE
TRANSLOCASE SUBUNIT
TIM44

(Saccharomyces
cerevisiae) 		PF04280
(Tim44) 		4 MET A 254
ILE A 301
ILE A 297
VAL A 298
 None
 0.99A 4olmA-3qk9A:
undetectable		 4olmA-3qk9A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhg PUTATIVE
PHOPHOTRIESTERASE

(Proteus
mirabilis) 		PF02126
(PTE) 		4 ASN A  82
ILE A  92
ILE A 117
VAL A 119
 None
 0.89A 4olmA-3rhgA:
undetectable		 4olmA-3rhgA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ry9 ANCESTRAL
GLUCOCORTICOID
RECEPTOR 1

(synthetic
construct) 		PF00104
(Hormone_recep) 		4 ASN A  33
MET A 115
ILE A 226
ILE A 227
 1CA  A 249 (-3.0A)
1CA  A 249 (-3.6A)
None
None
 0.78A 4olmA-3ry9A:
35.7		 4olmA-3ry9A:
54.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttp HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 ASN A  83
ILE A  64
ILE A  15
VAL A  62
 None
 0.79A 4olmA-3ttpA:
undetectable		 4olmA-3ttpA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u1j SERINE PROTEASE NS3

(Dengue virus) 		PF00949
(Peptidase_S7) 		4 ASN B 108
ILE B 139
ILE B 140
VAL B 146
 None
 0.98A 4olmA-3u1jB:
undetectable		 4olmA-3u1jB:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3whi SUBTILISIN E

(Bacillus
subtilis) 		PF00082
(Peptidase_S8)
PF05922
(Inhibitor_I9) 		4 MET A 209
ILE A 358
ILE A 101
VAL A 360
 None
 0.98A 4olmA-3whiA:
undetectable		 4olmA-3whiA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiq KOJIBIOSE
PHOSPHORYLASE

(Caldicellulosiruptor
saccharolyticus) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 MET A 641
ILE A 297
ILE A 295
VAL A 307
 None
 0.90A 4olmA-3wiqA:
undetectable		 4olmA-3wiqA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7x PROBABLE
OXIDOREDUCTASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 MET A 276
ILE A 236
ILE A 217
VAL A 232
 NAP  A 400 (-3.6A)
None
None
None
 0.74A 4olmA-4b7xA:
undetectable		 4olmA-4b7xA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bih UNCHARACTERIZED
LIPOPROTEIN
SAOUHSC_00053

(Staphylococcus
aureus) 		PF04507
(DUF576) 		4 ASN A 132
ILE A 135
ILE A 134
VAL A 127
 None
 1.01A 4olmA-4bihA:
undetectable		 4olmA-4bihA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4buj ANTIVIRAL PROTEIN
SKI8

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 MET C 119
ILE C 194
ILE C 200
VAL C 192
 None
 0.98A 4olmA-4bujC:
undetectable		 4olmA-4bujC:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djf CORRINOID/IRON-SULFU
R PROTEIN LARGE
SUBUNIT

(Moorella
thermoacetica) 		PF03599
(CdhD)
PF04060
(FeS) 		4 ASN C 115
ILE C  96
ILE C 131
VAL C  98
 None
 0.83A 4olmA-4djfC:
undetectable		 4olmA-4djfC:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dz4 AGMATINASE

(Burkholderia
thailandensis) 		PF00491
(Arginase) 		4 MET A 178
ILE A 231
ILE A 228
VAL A 232
 None
 0.90A 4olmA-4dz4A:
undetectable		 4olmA-4dz4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eg9 UNCHARACTERIZED
PROTEIN
SAOUHSC_02783

(Staphylococcus
aureus) 		PF04507
(DUF576) 		4 ASN A 136
ILE A 139
ILE A 138
VAL A 131
 None
 0.86A 4olmA-4eg9A:
undetectable		 4olmA-4eg9A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fj6 GLYCOSIDE HYDROLASE
FAMILY 33, CANDIDATE
SIALIDASE

(Parabacteroides
distasonis) 		PF13859
(BNR_3)
PF14873
(BNR_assoc_N) 		4 ASN A 163
ILE A  23
ILE A 173
VAL A  25
 None
 0.90A 4olmA-4fj6A:
undetectable		 4olmA-4fj6A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gud IMIDAZOLE GLYCEROL
PHOSPHATE SYNTHASE
SUBUNIT HISH

(Vibrio cholerae) 		PF00117
(GATase) 		4 ASN A  14
ILE A  31
ILE A   7
VAL A  29
 None
 0.82A 4olmA-4gudA:
undetectable		 4olmA-4gudA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB

(Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 ASN A 645
ILE A 633
ILE A 632
VAL A 619
 None
 0.99A 4olmA-4iglA:
undetectable		 4olmA-4iglA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ikn AP-3 COMPLEX SUBUNIT
MU-1

(Rattus
norvegicus) 		PF00928
(Adap_comp_sub) 		4 ASN A 372
ILE A 191
ILE A 190
VAL A 198
 ASN  A 372 ( 0.6A)
ILE  A 191 ( 0.7A)
ILE  A 190 ( 0.7A)
VAL  A 198 ( 0.6A)
 0.89A 4olmA-4iknA:
undetectable		 4olmA-4iknA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv5 ASPARTATE
CARBAMOYLTRANSFERASE
, PUTATIVE

(Trypanosoma
cruzi) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 MET A 317
ILE A 162
ILE A 164
VAL A 237
 None
 0.96A 4olmA-4iv5A:
undetectable		 4olmA-4iv5A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jn6 4-HYDROXY-2-OXOVALER
ATE ALDOLASE

(Mycobacterium
tuberculosis) 		PF00682
(HMGL-like)
PF07836
(DmpG_comm) 		4 MET A 270
ILE A   9
ILE A 253
VAL A  42
 None
 1.01A 4olmA-4jn6A:
undetectable		 4olmA-4jn6A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq8 CYTOCHROME P450 19A1

(Homo sapiens) 		PF00067
(p450) 		4 MET A 160
MET A 446
ILE A 132
ILE A 133
 None
None
HEM  A 601 (-3.8A)
ASD  A 602 (-4.0A)
 0.91A 4olmA-4kq8A:
1.7		 4olmA-4kq8A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kyi VIPD

(Legionella
pneumophila) 		PF01734
(Patatin) 		4 ASN A 178
ILE A 121
ILE A 176
VAL A 124
 None
 0.99A 4olmA-4kyiA:
undetectable		 4olmA-4kyiA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lis UDP-GLUCOSE
4-EPIMERASE

(Aspergillus
nidulans) 		PF16363
(GDP_Man_Dehyd) 		4 ASN A 122
ILE A 167
ILE A 171
VAL A 170
 None
None
None
IOD  A 406 ( 4.9A)
 0.95A 4olmA-4lisA:
undetectable		 4olmA-4lisA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8x CARBON DIOXIDE
CONCENTRATING
MECHANISM PROTEIN

(Nostoc sp. PCC
7120) 		PF03319
(EutN_CcmL) 		4 ASN 1  35
ILE 1  86
ILE 1  93
VAL 1  88
 None
 1.02A 4olmA-4n8x1:
undetectable		 4olmA-4n8x1:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psp ALPHA-FUCOSIDASE
GH29

(Fusarium
graminearum) 		PF01120
(Alpha_L_fucos)
PF16757
(Fucosidase_C) 		4 MET A 170
ILE A 108
ILE A 109
VAL A 112
 None
 0.99A 4olmA-4pspA:
undetectable		 4olmA-4pspA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pxd ALLANTOATE
AMIDOHYDROLASE

(Escherichia
coli) 		PF01546
(Peptidase_M20) 		4 ASN A 304
ILE A 317
ILE A 319
VAL A 218
 None
 1.01A 4olmA-4pxdA:
undetectable		 4olmA-4pxdA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
A''

(Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04998
(RNA_pol_Rpb1_5) 		4 MET B1035
ILE C 101
ILE C 102
VAL C 105
 None
 0.90A 4olmA-4qiwB:
undetectable		 4olmA-4qiwB:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qrk HYPOTHETICAL PROTEIN

(Clostridium
sporogenes) 		PF09922
(DUF2154)
PF17115
(Toast_rack_N) 		4 ASN A 234
ILE A 244
ILE A 242
VAL A 206
 None
 0.98A 4olmA-4qrkA:
undetectable		 4olmA-4qrkA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rph UDP-GALACTOPYRANOSE
MUTASE

(Mycobacterium
tuberculosis) 		no annotation 4 ASN B 210
MET B 369
ILE B 217
VAL B 219
 None
FAD  B 401 (-4.4A)
None
None
 0.78A 4olmA-4rphB:
undetectable		 4olmA-4rphB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1r ATP-DEPENDENT
6-PHOSPHOFRUCTOKINAS
E, PLATELET TYPE

(Homo sapiens) 		PF00365
(PFK) 		4 ASN A 684
ILE A 194
ILE A 195
VAL A 198
 None
 0.95A 4olmA-4u1rA:
undetectable		 4olmA-4u1rA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgk UDP-GALACTOPYRANOSE
MUTASE

(Corynebacterium
diphtheriae) 		PF03275
(GLF)
PF13450
(NAD_binding_8) 		4 ASN A 206
MET A 367
ILE A 213
VAL A 215
 None
FDA  A 403 (-4.2A)
None
None
 0.70A 4olmA-4xgkA:
undetectable		 4olmA-4xgkA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yk8 MEIOTICALLY
UP-REGULATED GENE 66
PROTEIN

(Schizosaccharomyces
pombe) 		PF07855
(ATG101) 		4 ASN A  57
MET A  81
ILE A  41
VAL A  43
 None
 0.96A 4olmA-4yk8A:
undetectable		 4olmA-4yk8A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypj BETA GALACTOSIDASE

(Bacillus
circulans) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		4 ASN A 391
ILE A 375
ILE A 397
VAL A 377
 None
 0.84A 4olmA-4ypjA:
undetectable		 4olmA-4ypjA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a35 GLYCINE CLEAVAGE
SYSTEM H PROTEIN

(Streptococcus
pyogenes) 		PF01597
(GCV_H) 		4 ASN A   6
ILE A  93
ILE A  19
VAL A  94
 None
 0.83A 4olmA-5a35A:
undetectable		 4olmA-5a35A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ar6 RIBONUCLEASE 4

(Sus scrofa) 		PF00074
(RnaseA) 		4 MET A   0
ILE A  50
ILE A  53
VAL A  13
 None
None
None
EDO  A1120 (-4.4A)
 0.99A 4olmA-5ar6A:
undetectable		 4olmA-5ar6A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ayn SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER)

(Bdellovibrio
bacteriovorus) 		PF06963
(FPN1) 		4 ASN A 375
ILE A 132
ILE A  68
VAL A  76
 None
 0.99A 4olmA-5aynA:
undetectable		 4olmA-5aynA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esc HUPZ

(Streptococcus
sp. 'group A') 		PF01243
(Putative_PNPOx) 		4 MET A 101
ILE A  62
ILE A  64
VAL A  17
 None
 1.00A 4olmA-5escA:
undetectable		 4olmA-5escA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl3 PILI RETRACTION
PROTEIN PILT

(Thermus
thermophilus) 		PF00437
(T2SSE) 		4 MET A 211
ILE A 295
ILE A 293
VAL A 124
 None
 0.97A 4olmA-5fl3A:
undetectable		 4olmA-5fl3A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqf LACTO-N-BIOSIDASE

(Bifidobacterium
longum) 		no annotation 4 ASN A 333
ILE A 234
ILE A 251
VAL A 214
 None
 0.94A 4olmA-5gqfA:
undetectable		 4olmA-5gqfA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hci GPN-LOOP GTPASE 1

(Saccharomyces
cerevisiae) 		PF03029
(ATP_bind_1) 		4 MET A  20
ILE A  86
ILE A  90
VAL A  89
 None
 1.01A 4olmA-5hciA:
undetectable		 4olmA-5hciA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjd COLLAGEN TYPE IV
ALPHA-3-BINDING
PROTEIN

(Homo sapiens) 		PF01852
(START) 		4 ASN B 504
ILE B 464
ILE B 465
VAL B 454
 PGE  B 604 (-4.0A)
None
None
None
 0.99A 4olmA-5jjdB:
undetectable		 4olmA-5jjdB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnq 3-KETOACYL-COA
THIOLASE-LIKE
PROTEIN

(Leishmania
mexicana) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		4 MET A 279
ILE A 395
ILE A 398
VAL A 130
 None
 0.86A 4olmA-5lnqA:
undetectable		 4olmA-5lnqA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mm2 CAPSID PROTEIN VP4B

(Nora virus) 		no annotation 4 MET B  71
ILE B 119
ILE B 121
VAL B 205
 None
 0.94A 4olmA-5mm2B:
undetectable		 4olmA-5mm2B:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwp MINERALOCORTICOID
RECEPTOR

(Homo sapiens) 		no annotation 4 ASN A 770
MET A 852
ILE A 963
ILE A 964
 ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
None
None
 0.72A 4olmA-5mwpA:
36.1		 4olmA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nc8 POTASSIUM EFFLUX
SYSTEM PROTEIN

(Shewanella
denitrificans) 		PF02254
(TrkA_N) 		4 ASN A 450
ILE A 410
ILE A 411
VAL A 475
 None
 1.01A 4olmA-5nc8A:
undetectable		 4olmA-5nc8A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ngy DSR-M GLUCANSUCRASE
INACTIVE MUTANT
E715Q

(Leuconostoc
citreum) 		no annotation 4 ASN A1284
ILE A1214
ILE A1213
VAL A1195
 None
 0.94A 4olmA-5ngyA:
undetectable		 4olmA-5ngyA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o8x SOLUBLE LYTIC
TRANSGLYCOSYLASE B

(Pseudomonas
aeruginosa) 		no annotation 4 MET A 171
ILE A  99
ILE A  98
VAL A  94
 CAC  A 402 (-4.2A)
None
None
None
 0.95A 4olmA-5o8xA:
undetectable		 4olmA-5o8xA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE

(Zobellia
galactanivorans) 		no annotation 4 MET A 529
ILE A 608
ILE A 368
VAL A 374
 None
 0.95A 4olmA-5opqA:
undetectable		 4olmA-5opqA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szm PCDHGA8 OR
PROTOCADHERIN GAMMA
A8

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 ASN A 146
ILE A 199
ILE A 201
VAL A 111
 None
 0.96A 4olmA-5szmA:
undetectable		 4olmA-5szmA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t2z PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 ASN A  83
ILE A  64
ILE A  15
VAL A  62
 None
 0.96A 4olmA-5t2zA:
undetectable		 4olmA-5t2zA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tk6 OXSA PROTEIN

(Bacillus
megaterium) 		PF12917
(HD_2) 		4 ASN A  55
ILE A 127
ILE A 124
VAL A 128
 None
 0.99A 4olmA-5tk6A:
2.2		 4olmA-5tk6A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tpc BOTULINUM NEUROTOXIN
TYPE A

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 MET A1004
ILE A 983
ILE A 984
VAL A 998
 None
 1.02A 4olmA-5tpcA:
undetectable		 4olmA-5tpcA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uqz GLUCAN-BINDING
PROTEIN C, GBPC

(Streptococcus
mutans) 		no annotation 4 ASN A 264
ILE A 272
ILE A 262
VAL A 275
 None
 0.98A 4olmA-5uqzA:
undetectable		 4olmA-5uqzA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze4 DIHYDROXY-ACID
DEHYDRATASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		no annotation 4 MET A 102
ILE A  94
ILE A 117
VAL A  59
 None
 0.91A 4olmA-5ze4A:
undetectable		 4olmA-5ze4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zqz TRIFUNCTIONAL ENZYME
SUBUNIT ALPHA,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 MET A 215
ILE A 304
ILE A 305
VAL A 308
 None
 1.01A 4olmA-5zqzA:
undetectable		 4olmA-5zqzA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs PUTATIVE CORE
PROTEIN NTPASE/VP5

(Aquareovirus C) 		no annotation 4 MET 4 424
ILE 4 314
ILE 4 292
VAL 4 317
 None
 1.00A 4olmA-5zvs4:
undetectable		 4olmA-5zvs4:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b82 CYTOCHROME P450,
FAMILY 17, SUBFAMILY
A, POLYPEPTIDE 1

(Danio rerio) 		no annotation 4 MET A 372
ILE A 155
ILE A 159
VAL A 191
 HEM  A 601 ( 4.4A)
None
None
None
 0.93A 4olmA-6b82A:
undetectable		 4olmA-6b82A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f91 PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		no annotation 4 ASN A 644
ILE A 668
ILE A 646
VAL A 670
 None
 0.92A 4olmA-6f91A:
undetectable		 4olmA-6f91A:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fiv RETROPEPSIN

(Feline
immunodeficiency
virus) 		PF00077
(RVP) 		4 MET A  56
ILE A  18
ILE A  25
VAL A  20
 3TL  A 201 (-4.7A)
None
None
None
 1.02A 4olmA-6fivA:
undetectable		 4olmA-6fivA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5

(Mus musculus) 		no annotation 4 MET L 421
ILE L 395
ILE L 399
VAL L 315
 None
 0.91A 4olmA-6g2jL:
undetectable		 4olmA-6g2jL:
14.17