SIMILAR PATTERNS OF AMINO ACIDS FOR 4OKX_A_198A1002_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dju AROMATIC
AMINOTRANSFERASE

(Pyrococcus
horikoshii) 		PF00155
(Aminotran_1_2) 		4 LEU A 305
ASN A 306
MET A 339
LEU A 383
 None
 1.13A 4okxA-1djuA:
0.0		 4okxA-1djuA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dml DNA POLYMERASE
PROCESSIVITY FACTOR

(Human
alphaherpesvirus
1) 		PF02282
(Herpes_UL42) 		4 LEU A 109
MET A  61
LEU A 125
ILE A 140
 None
 1.07A 4okxA-1dmlA:
undetectable		 4okxA-1dmlA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gzj EGI

(Thermoascus
aurantiacus) 		PF00150
(Cellulase) 		4 LEU A 145
ASN A 146
MET A  62
ILE A 163
 None
 1.12A 4okxA-1gzjA:
undetectable		 4okxA-1gzjA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hp1 5'-NUCLEOTIDASE

(Escherichia
coli) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		4 MET A 218
MET A 236
LEU A 245
ILE A 165
 None
 1.14A 4okxA-1hp1A:
undetectable		 4okxA-1hp1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htd ATROLYSIN C

(Crotalus atrox) 		PF01421
(Reprolysin) 		4 ASN A  41
MET A 166
MET A 150
LEU A  47
 None
 1.09A 4okxA-1htdA:
0.0		 4okxA-1htdA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3u ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1)
PF10415
(FumaraseC_C) 		4 LEU A 369
MET A 376
LEU A 157
ILE A 151
 None
 1.16A 4okxA-1j3uA:
1.1		 4okxA-1j3uA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k3v CAPSID PROTEIN VP2

(Ungulate
protoparvovirus
1) 		PF00740
(Parvo_coat) 		4 LEU A  72
ASN A  73
LEU A 150
ILE A 153
 None
 1.16A 4okxA-1k3vA:
undetectable		 4okxA-1k3vA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mkp PYST1

(Homo sapiens) 		PF00782
(DSPc) 		4 LEU A 314
MET A 325
LEU A 211
ILE A 276
 None
 0.93A 4okxA-1mkpA:
undetectable		 4okxA-1mkpA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qjc PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Escherichia
coli) 		PF01467
(CTP_transf_like) 		4 LEU A 146
ASN A  16
MET A  45
LEU A  54
 None
 1.08A 4okxA-1qjcA:
undetectable		 4okxA-1qjcA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s3i 10-FORMYLTETRAHYDROF
OLATE DEHYDROGENASE

(Rattus
norvegicus) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 LEU A 242
MET A 300
LEU A 277
ILE A 220
 None
 0.99A 4okxA-1s3iA:
undetectable		 4okxA-1s3iA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tnd TRANSDUCIN

(Bos taurus) 		PF00503
(G-alpha) 		4 LEU A 306
ASN A 251
MET A 239
LEU A 262
 None
 1.13A 4okxA-1tndA:
undetectable		 4okxA-1tndA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uek 4-(CYTIDINE
5'-DIPHOSPHO)-2C-MET
HYL-D-ERYTHRITOL
KINASE

(Thermus
thermophilus) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A  59
ASN A  58
LEU A 102
ILE A  79
 None
 0.88A 4okxA-1uekA:
undetectable		 4okxA-1uekA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w25 STALKED-CELL
DIFFERENTIATION
CONTROLLING PROTEIN

(Caulobacter
vibrioides) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		4 LEU A  39
MET A  56
LEU A  52
ILE A  77
 None
 1.15A 4okxA-1w25A:
undetectable		 4okxA-1w25A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yc9 MULTIDRUG RESISTANCE
PROTEIN

(Vibrio cholerae) 		PF02321
(OEP) 		4 LEU A 257
ASN A 260
LEU A 199
ILE A 276
 None
 1.13A 4okxA-1yc9A:
undetectable		 4okxA-1yc9A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aqw PUTATIVE
OROTIDINE-MONOPHOSPH
ATE-DECARBOXYLASE

(Plasmodium
yoelii) 		PF00215
(OMPdecase) 		4 LEU A 194
MET A 137
LEU A 265
ILE A 255
 None
 0.96A 4okxA-2aqwA:
undetectable		 4okxA-2aqwA:
20.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		6 LEU A 704
ASN A 705
MET A 749
MET A 787
LEU A 873
ILE A 899
 BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 (-4.3A)
BHM  A   1 (-3.6A)
BHM  A   1 (-4.4A)
None
 0.45A 4okxA-2ax9A:
41.7		 4okxA-2ax9A:
99.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b1p MITOGEN-ACTIVATED
PROTEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 203
ASN A 122
MET A 256
LEU A 170
 None
 1.10A 4okxA-2b1pA:
undetectable		 4okxA-2b1pA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cb0 GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Pyrococcus
furiosus) 		PF01380
(SIS) 		4 LEU A  48
MET A  55
LEU A 147
ILE A 109
 None
 0.90A 4okxA-2cb0A:
undetectable		 4okxA-2cb0A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4n DU

(Mason-Pfizer
monkey virus) 		PF00692
(dUTPase) 		4 LEU A 169
MET A 137
LEU A 142
ILE A 158
 None
None
None
DUP  A 777 ( 4.5A)
 1.09A 4okxA-2d4nA:
undetectable		 4okxA-2d4nA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e4u METABOTROPIC
GLUTAMATE RECEPTOR 3

(Rattus
norvegicus) 		PF01094
(ANF_receptor)
PF07562
(NCD3G) 		4 MET A 407
MET A 422
LEU A  39
ILE A  76
 None
 1.16A 4okxA-2e4uA:
undetectable		 4okxA-2e4uA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5f HYPOTHETICAL PROTEIN
PH0510

(Pyrococcus
horikoshii) 		PF01380
(SIS) 		4 LEU A  48
MET A  55
LEU A 147
ILE A 109
 None
 0.83A 4okxA-2e5fA:
undetectable		 4okxA-2e5fA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixn SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
ACTIVATOR 2

(Saccharomyces
cerevisiae) 		PF03095
(PTPA) 		4 LEU A 137
ASN A 138
LEU A 297
ILE A 117
 None
 1.01A 4okxA-2ixnA:
undetectable		 4okxA-2ixnA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2r GLUCOKINASE 1,
PUTATIVE

(Trypanosoma
cruzi) 		PF02685
(Glucokinase) 		4 MET A  81
MET A  76
LEU A  11
ILE A   3
 None
 1.10A 4okxA-2q2rA:
undetectable		 4okxA-2q2rA:
20.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q3y ANCESTRAL CORTICIOD
RECEPTOR

(unidentified) 		PF00104
(Hormone_recep) 		4 LEU A  32
ASN A  33
LEU A 201
ILE A 227
 1CA  A 247 (-4.0A)
1CA  A 247 (-2.9A)
1CA  A 247 ( 4.2A)
None
 0.74A 4okxA-2q3yA:
37.1		 4okxA-2q3yA:
59.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q3y ANCESTRAL CORTICIOD
RECEPTOR

(unidentified) 		PF00104
(Hormone_recep) 		4 LEU A  32
MET A 115
LEU A 201
ILE A 227
 1CA  A 247 (-4.0A)
1CA  A 247 ( 3.7A)
1CA  A 247 ( 4.2A)
None
 0.92A 4okxA-2q3yA:
37.1		 4okxA-2q3yA:
59.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzu PUTATIVE SULFATASE
YIDJ

(Bacteroides
fragilis) 		PF00884
(Sulfatase) 		4 LEU A 384
MET A 338
LEU A 361
ILE A 375
 None
 1.08A 4okxA-2qzuA:
undetectable		 4okxA-2qzuA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6o THIOREDOXIN
GLUTATHIONE
REDUCTASE

(Schistosoma
mansoni) 		PF00462
(Glutaredoxin)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 MET A 197
MET A 165
LEU A 279
ILE A 144
 None
 1.09A 4okxA-2v6oA:
undetectable		 4okxA-2v6oA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xij METHYLMALONYL-COA
MUTASE,
MITOCHONDRIAL

(Homo sapiens) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding) 		4 LEU A 173
ASN A 120
MET A 186
LEU A 179
 None
 1.16A 4okxA-2xijA:
undetectable		 4okxA-2xijA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zii VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 74

(Saccharomyces
cerevisiae) 		PF05719
(GPP34) 		4 LEU A 228
MET A  76
LEU A 255
ILE A 249
 None
 1.11A 4okxA-2ziiA:
undetectable		 4okxA-2ziiA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN

(Archaeoglobus
fulgidus) 		PF02655
(ATP-grasp_3) 		4 LEU A  98
ASN A  97
LEU A 249
ILE A 105
 None
 1.01A 4okxA-3df7A:
undetectable		 4okxA-3df7A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyu NUCLEAR HORMONE
RECEPTOR OF THE
STEROID/THYROID
HORMONE RECEPTORS
SUPERFAMILY

(Strongyloides
stercoralis) 		PF00104
(Hormone_recep) 		4 LEU A 573
ASN A 577
MET A 595
LEU A 588
 None
 1.07A 4okxA-3gyuA:
17.9		 4okxA-3gyuA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbx GLUTAMATE
DECARBOXYLASE 1

(Arabidopsis
thaliana) 		PF00282
(Pyridoxal_deC) 		4 LEU A 417
MET A 441
LEU A 380
ILE A 414
 None
 1.13A 4okxA-3hbxA:
undetectable		 4okxA-3hbxA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1j ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF05362
(Lon_C)
PF13654
(AAA_32) 		4 LEU A 292
MET A 304
LEU A  64
ILE A  53
 None
 1.16A 4okxA-3k1jA:
undetectable		 4okxA-3k1jA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE

(Pseudomonas
aeruginosa) 		PF01979
(Amidohydro_1) 		4 LEU A 406
ASN A 407
MET A  52
LEU A 331
 None
 1.15A 4okxA-3mduA:
undetectable		 4okxA-3mduA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o98 BIFUNCTIONAL
GLUTATHIONYLSPERMIDI
NE
SYNTHETASE/AMIDASE

(Escherichia
coli) 		PF03738
(GSP_synth)
PF05257
(CHAP) 		4 LEU A 614
ASN A 360
MET A 321
LEU A 263
 None
 1.15A 4okxA-3o98A:
undetectable		 4okxA-3o98A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oix DIHYDROOROTATE
OXIDASE
PUTATIVE
DIHYDROOROTATE
DEHYDROGENASE

(Streptococcus
mutans) 		PF01180
(DHO_dh) 		4 LEU A  17
MET A 292
LEU A 300
ILE A   8
 None
MLY  A 289 ( 4.5A)
None
None
 0.89A 4okxA-3oixA:
undetectable		 4okxA-3oixA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3os4 NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Yersinia pestis) 		PF04095
(NAPRTase) 		4 LEU A 154
ASN A 158
LEU A 171
ILE A 166
 None
 0.84A 4okxA-3os4A:
undetectable		 4okxA-3os4A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pa8 TOXIN B

(Clostridioides
difficile) 		PF11713
(Peptidase_C80) 		4 LEU A 152
ASN A 151
LEU A  41
ILE A  38
 None
IHP  A 257 ( 4.0A)
None
None
 1.13A 4okxA-3pa8A:
undetectable		 4okxA-3pa8A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6y ASPARTASE

(Bacillus sp.
YM55-1) 		PF00206
(Lyase_1) 		4 LEU A 369
MET A 376
LEU A 157
ILE A 151
 LEU  A 369 ( 0.5A)
MET  A 376 ( 0.0A)
LEU  A 157 ( 0.6A)
ILE  A 151 ( 0.6A)
 1.11A 4okxA-3r6yA:
2.0		 4okxA-3r6yA:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ry9 ANCESTRAL
GLUCOCORTICOID
RECEPTOR 1

(synthetic
construct) 		PF00104
(Hormone_recep) 		4 LEU A  32
ASN A  33
LEU A 201
ILE A 227
 1CA  A 249 (-3.9A)
1CA  A 249 (-3.0A)
1CA  A 249 ( 4.2A)
None
 0.64A 4okxA-3ry9A:
36.5		 4okxA-3ry9A:
54.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ry9 ANCESTRAL
GLUCOCORTICOID
RECEPTOR 1

(synthetic
construct) 		PF00104
(Hormone_recep) 		4 LEU A  32
MET A 115
LEU A 201
ILE A 227
 1CA  A 249 (-3.9A)
1CA  A 249 (-3.6A)
1CA  A 249 ( 4.2A)
None
 0.93A 4okxA-3ry9A:
36.5		 4okxA-3ry9A:
54.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sjn MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Shewanella
pealeana) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 199
MET A 212
LEU A 221
ILE A 270
 None
 1.10A 4okxA-3sjnA:
undetectable		 4okxA-3sjnA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhp CALCIUM-BINDING
PROTEIN 39-LIKE

(Homo sapiens) 		PF08569
(Mo25) 		4 LEU A 257
ASN A 254
LEU A 229
ILE A 236
 None
 1.16A 4okxA-3zhpA:
undetectable		 4okxA-3zhpA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyt ESTERASE A

(Paenarthrobacter
nitroguajacolicus) 		PF00144
(Beta-lactamase) 		4 LEU A 242
ASN A 124
MET A 157
LEU A 187
 None
 1.08A 4okxA-3zytA:
undetectable		 4okxA-3zytA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aig ADAMALYSIN II

(Crotalus
adamanteus) 		PF01421
(Reprolysin) 		4 ASN A  41
MET A 166
MET A 150
LEU A  47
 None
 1.11A 4okxA-4aigA:
undetectable		 4okxA-4aigA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bnd ALPHA-PHOSPHOGLUCOMU
TASE

(Lactococcus
lactis) 		PF03332
(PMM) 		4 LEU B  62
ASN B  61
LEU B  67
ILE B  36
 None
 1.15A 4okxA-4bndB:
undetectable		 4okxA-4bndB:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0d CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF04054
(Not1) 		4 LEU A2267
ASN A2268
LEU A2308
ILE A2126
 None
 1.14A 4okxA-4c0dA:
undetectable		 4okxA-4c0dA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8d GLYCOSYL HYDROLASE,
FAMILY 35

(Streptococcus
pneumoniae) 		PF01301
(Glyco_hydro_35) 		4 LEU A 274
MET A 326
LEU A  20
ILE A  88
 None
 1.00A 4okxA-4e8dA:
undetectable		 4okxA-4e8dA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emd 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE

(Mycobacteroides
abscessus) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A  79
ASN A  78
LEU A 122
ILE A  99
 None
 1.08A 4okxA-4emdA:
undetectable		 4okxA-4emdA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ezb UNCHARACTERIZED
CONSERVED PROTEIN

(Sinorhizobium
meliloti) 		PF03807
(F420_oxidored)
PF09130
(DUF1932) 		4 LEU A  28
MET A 156
LEU A  69
ILE A  62
 None
 1.11A 4okxA-4ezbA:
undetectable		 4okxA-4ezbA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ezd UREA TRANSPORTER 1

(Bos taurus) 		PF03253
(UT) 		4 LEU A 159
ASN A 160
LEU A 342
ILE A 359
 None
None
SPL  A 408 ( 4.5A)
None
 0.91A 4okxA-4ezdA:
undetectable		 4okxA-4ezdA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgm AMINOPEPTIDASE N
FAMILY PROTEIN

(Idiomarina
loihiensis) 		PF05299
(Peptidase_M61)
PF13180
(PDZ_2) 		4 ASN A 429
MET A 405
MET A 309
LEU A 387
 None
 1.13A 4okxA-4fgmA:
undetectable		 4okxA-4fgmA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN

(Pseudomonas) 		PF01804
(Penicil_amidase) 		4 ASN B   3
MET B 157
LEU B 192
ILE B 238
 None
 1.11A 4okxA-4hstB:
undetectable		 4okxA-4hstB:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htf S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE

(Escherichia
coli) 		PF13847
(Methyltransf_31) 		4 LEU B 139
MET B  41
LEU B  46
ILE B  70
 None
 1.05A 4okxA-4htfB:
undetectable		 4okxA-4htfB:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i70 INOSINE-ADENOSINE-GU
ANOSINE-NUCLEOSIDE
HYDROLASE

(Trypanosoma
brucei) 		PF01156
(IU_nuc_hydro) 		4 LEU A  21
ASN A  25
MET A 241
ILE A  61
 None
 0.98A 4okxA-4i70A:
undetectable		 4okxA-4i70A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i9u L-LACTATE
DEHYDROGENASE A
CHAIN

(Oryctolagus
cuniculus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 LEU A 108
ASN A 107
LEU A 142
ILE A 325
 None
 1.05A 4okxA-4i9uA:
undetectable		 4okxA-4i9uA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k17 LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A

(Mus musculus) 		PF13516
(LRR_6) 		5 LEU A  48
MET A  97
MET A  95
LEU A  55
ILE A  20
 None
 1.07A 4okxA-4k17A:
undetectable		 4okxA-4k17A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kng LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 256
ASN A 280
LEU A 241
ILE A 286
 None
 0.92A 4okxA-4kngA:
undetectable		 4okxA-4kngA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt1 LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4

(Homo sapiens) 		PF01462
(LRRNT)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 247
ASN A 271
LEU A 232
ILE A 277
 None
 0.91A 4okxA-4kt1A:
undetectable		 4okxA-4kt1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4li2 LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4

(Xenopus
tropicalis) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 250
ASN A 274
LEU A 235
ILE A 280
 None
 1.06A 4okxA-4li2A:
undetectable		 4okxA-4li2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mn8 LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 539
ASN A 537
MET A 547
LEU A 532
 None
 1.11A 4okxA-4mn8A:
undetectable		 4okxA-4mn8A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mna LRR RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE FLS2

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 539
ASN A 537
MET A 547
LEU A 532
 None
 1.07A 4okxA-4mnaA:
undetectable		 4okxA-4mnaA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mrm GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1

(Homo sapiens) 		PF01094
(ANF_receptor) 		5 LEU A  79
ASN A  83
MET A 126
LEU A 360
ILE A  88
 None
 1.36A 4okxA-4mrmA:
undetectable		 4okxA-4mrmA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5a PROTEIN EFR3

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 457
MET A 470
LEU A 420
ILE A 449
 None
 1.11A 4okxA-4n5aA:
undetectable		 4okxA-4n5aA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nml RIBULOSE 5-PHOSPHATE
ISOMERASE

(Toxoplasma
gondii) 		PF06026
(Rib_5-P_isom_A) 		4 LEU A  28
MET A  45
LEU A  53
ILE A  79
 None
 0.99A 4okxA-4nmlA:
undetectable		 4okxA-4nmlA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4px9 ATP-DEPENDENT RNA
HELICASE DDX3X

(Homo sapiens) 		PF00270
(DEAD) 		4 LEU A 346
MET A 370
LEU A 270
ILE A 282
 None
 0.89A 4okxA-4px9A:
undetectable		 4okxA-4px9A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1l SNAKE VENOM
METALLOPROTEINASE
LEUCUROLYSIN-A

(Bothrops
leucurus) 		PF01421
(Reprolysin) 		4 LEU A  56
MET A  36
MET A 140
LEU A  10
 None
 0.84A 4okxA-4q1lA:
undetectable		 4okxA-4q1lA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfh GLUCOSE-6-PHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF00342
(PGI) 		4 LEU A  88
MET A 357
MET A 546
LEU A 530
 None
 1.15A 4okxA-4qfhA:
undetectable		 4okxA-4qfhA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxe LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, LINKER,
VARIABLE LYMPHOCYTE
RECEPTOR B

(Eptatretus
burgeri;
Homo sapiens) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 247
ASN A 271
LEU A 232
ILE A 277
 None
 0.94A 4okxA-4qxeA:
undetectable		 4okxA-4qxeA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwa SOLUBLE CYTOCHROME
B562,DELTA-TYPE
OPIOID RECEPTOR

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		4 LEU A 313
ASN A 314
LEU A 321
ILE A  88
 None
 0.96A 4okxA-4rwaA:
undetectable		 4okxA-4rwaA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txd CSC2

(Thermofilum
pendens) 		no annotation 4 LEU A 234
MET A  89
LEU A 331
ILE A  24
 None
 1.00A 4okxA-4txdA:
undetectable		 4okxA-4txdA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ufs LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 5

(Homo sapiens) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13855
(LRR_8) 		4 LEU A 256
ASN A 280
LEU A 241
ILE A 286
 None
 1.10A 4okxA-4ufsA:
undetectable		 4okxA-4ufsA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9l PROTEIN ACDH-11,
ISOFORM B

(Caenorhabditis
elegans) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M) 		4 LEU A 330
ASN A 331
LEU A 470
ILE A 416
 None
 1.05A 4okxA-4y9lA:
1.9		 4okxA-4y9lA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zk3 SERPIN B3

(Homo sapiens) 		PF00079
(Serpin) 		4 LEU A 325
MET A 317
LEU A 174
ILE A 168
 None
 1.09A 4okxA-4zk3A:
undetectable		 4okxA-4zk3A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ztd PROLIFERATING CELL
NUCLEAR ANTIGEN

(Homo sapiens) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 LEU A  79
MET A 116
LEU A  90
ILE A  87
 None
 1.12A 4okxA-4ztdA:
undetectable		 4okxA-4ztdA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aee ALPHA-GLUCOSIDASE
YIHQ

(Escherichia
coli) 		PF01055
(Glyco_hydro_31) 		4 LEU A 148
ASN A 427
LEU A 217
ILE A 424
 None
 1.12A 4okxA-5aeeA:
undetectable		 4okxA-5aeeA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awm STRESS-ACTIVATED
PROTEIN KINASE JNK

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		4 LEU A 163
ASN A  82
MET A 216
LEU A 130
 None
 1.16A 4okxA-5awmA:
undetectable		 4okxA-5awmA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cju ISOBUTYRYL-COA
MUTASE FUSED

(Cupriavidus
metallidurans) 		PF01642
(MM_CoA_mutase)
PF02310
(B12-binding)
PF03308
(ArgK) 		4 MET A 660
MET A 690
LEU A1075
ILE A 643
 None
 1.06A 4okxA-5cjuA:
undetectable		 4okxA-5cjuA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF13416
(SBP_bac_8) 		4 LEU A 177
ASN A 173
LEU A 170
ILE A 290
 None
 1.16A 4okxA-5hzwA:
undetectable		 4okxA-5hzwA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6s ENDOGLUCANASE

(Talaromyces
verruculosus) 		PF00150
(Cellulase) 		4 LEU A 154
ASN A 155
MET A  71
ILE A 172
 None
 1.10A 4okxA-5i6sA:
undetectable		 4okxA-5i6sA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i77 ENDO-BETA-1,
4-GLUCANASE

(Aspergillus
niger) 		PF00150
(Cellulase) 		4 LEU A 172
ASN A 173
MET A  89
ILE A 190
 None
 1.12A 4okxA-5i77A:
undetectable		 4okxA-5i77A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k04 N-TERMINAL
ACETYLTRANSFERASE B
COMPLEX SUBUNIT NAT3
UNCHARACTERIZED
PROTEIN

(Candida
albicans) 		PF08445
(FR47)
PF09797
(NatB_MDM20) 		4 LEU B  15
ASN B  16
MET B  59
ILE A 432
 None
 0.99A 4okxA-5k04B:
undetectable		 4okxA-5k04B:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksd ATPASE 2, PLASMA
MEMBRANE-TYPE

(Arabidopsis
thaliana) 		PF00122
(E1-E2_ATPase)
PF00690
(Cation_ATPase_N)
PF00702
(Hydrolase) 		4 LEU A 277
ASN A 276
MET A  75
LEU A  83
 None
 1.13A 4okxA-5ksdA:
undetectable		 4okxA-5ksdA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwp MINERALOCORTICOID
RECEPTOR

(Homo sapiens) 		no annotation 5 LEU A 769
ASN A 770
MET A 852
LEU A 938
ILE A 964
 ECV  A1101 (-4.7A)
ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
None
 0.87A 4okxA-5mwpA:
37.0		 4okxA-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mx0 FIBROMODULIN

(Homo sapiens) 		PF01462
(LRRNT)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 LEU A 285
ASN A 282
LEU A 300
ILE A 325
 None
 1.16A 4okxA-5mx0A:
undetectable		 4okxA-5mx0A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8n EVPB FAMILY TYPE VI
SECRETION PROTEIN

(Pseudomonas
aeruginosa) 		no annotation 4 LEU B 119
MET B 182
LEU B 163
ILE B 116
 None
 1.04A 4okxA-5n8nB:
undetectable		 4okxA-5n8nB:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ng7 EPOXIDE HYDROLASE

(metagenome) 		no annotation 4 LEU A 124
ASN A 125
LEU A 234
ILE A 249
 None
 1.11A 4okxA-5ng7A:
undetectable		 4okxA-5ng7A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		4 LEU T2469
ASN T2470
LEU T2476
ILE T2546
 None
 1.11A 4okxA-5ojsT:
undetectable		 4okxA-5ojsT:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol2 ACYL-COA
DEHYDROGENASE

(Clostridioides
difficile) 		no annotation 4 MET C  44
MET C  50
LEU C 119
ILE C 160
 None
 1.13A 4okxA-5ol2C:
undetectable		 4okxA-5ol2C:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ucy TUBULIN ALPHA CHAIN

(Tetrahymena
thermophila) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 LEU A 259
ASN A 380
MET A 318
ILE A 384
 None
 1.10A 4okxA-5ucyA:
undetectable		 4okxA-5ucyA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v6p ERAD-ASSOCIATED E3
UBIQUITIN-PROTEIN
LIGASE HRD1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 156
ASN A 153
LEU A  66
ILE A 124
 None
 1.14A 4okxA-5v6pA:
undetectable		 4okxA-5v6pA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v9p LYSINE-SPECIFIC
DEMETHYLASE 5A

(Homo sapiens) 		PF00628
(PHD)
PF01388
(ARID)
PF02373
(JmjC)
PF02375
(JmjN)
PF02928
(zf-C5HC2)
PF08429
(PLU-1) 		4 LEU A  88
MET A 540
LEU A 533
ILE A 107
 None
 1.12A 4okxA-5v9pA:
undetectable		 4okxA-5v9pA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfm ALPHA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 ASN A 533
MET A 349
LEU A 365
ILE A 436
 None
 1.04A 4okxA-5xfmA:
undetectable		 4okxA-5xfmA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 LEU A1011
MET A1115
LEU A1460
ILE A1467
 None
 1.11A 4okxA-5xsyA:
undetectable		 4okxA-5xsyA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xtd NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
1

(Homo sapiens) 		PF15879
(MWFE) 		4 LEU s  83
MET s 225
MET s  17
ILE s 105
 None
 1.03A 4okxA-5xtds:
undetectable		 4okxA-5xtds:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zal ENDORIBONUCLEASE
DICER

(Homo sapiens) 		no annotation 4 LEU A1359
ASN A1355
LEU A1567
ILE A1327
 None
 1.12A 4okxA-5zalA:
undetectable		 4okxA-5zalA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zm4 DIOXYGENASE ANDA

(Aspergillus
stellatus) 		no annotation 4 LEU A  83
MET A  55
LEU A 163
ILE A  43
 None
 1.16A 4okxA-5zm4A:
undetectable		 4okxA-5zm4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo sapiens) 		no annotation 4 LEU A1551
ASN A1386
MET A1602
LEU A1497
 None
 1.16A 4okxA-6bhcA:
undetectable		 4okxA-6bhcA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byw GOXA

(Pseudoalteromonas
luteoviolacea) 		no annotation 4 MET B 371
MET B 592
LEU B 621
ILE B   8
 None
 0.96A 4okxA-6bywB:
undetectable		 4okxA-6bywB:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6el8 FORKHEAD BOX PROTEIN
N1

(Homo sapiens) 		no annotation 4 LEU A 322
ASN A 321
LEU A 283
ILE A 277
 None
 1.06A 4okxA-6el8A:
undetectable		 4okxA-6el8A:
14.69