SIMILAR PATTERNS OF AMINO ACIDS FOR 4OKW_A_198A1001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0i DNA LIGASE

(Escherichia
virus T7) 		PF01068
(DNA_ligase_A_M) 		4 LEU A 154
MET A 177
LEU A  90
ILE A   4
 None
 0.94A 4okwA-1a0iA:
0.0		 4okwA-1a0iA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cm0 P300/CBP ASSOCIATING
FACTOR

(Homo sapiens) 		no annotation 4 LEU B 603
ASN B 604
LEU B 593
ILE B 571
 None
 0.85A 4okwA-1cm0B:
0.0		 4okwA-1cm0B:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0p ANTIGEN 85-B

(Mycobacterium
tuberculosis) 		PF00756
(Esterase) 		4 LEU A  38
ASN A  49
LEU A 105
ILE A  22
 None
 0.99A 4okwA-1f0pA:
undetectable		 4okwA-1f0pA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fp2 ISOFLAVONE
O-METHYLTRANSFERASE

(Medicago sativa) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 LEU A 314
ASN A 315
LEU A 130
ILE A 134
 None
 1.05A 4okwA-1fp2A:
0.0		 4okwA-1fp2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i60 IOLI PROTEIN

(Bacillus
subtilis) 		PF01261
(AP_endonuc_2) 		4 ASN A  66
LEU A  16
LEU A  11
ILE A  31
 None
 0.89A 4okwA-1i60A:
0.0		 4okwA-1i60A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibj CYSTATHIONINE
BETA-LYASE

(Arabidopsis
thaliana) 		PF01053
(Cys_Met_Meta_PP) 		4 ASN A 254
LEU A 291
LEU A 142
ILE A 271
 None
 1.04A 4okwA-1ibjA:
0.0		 4okwA-1ibjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iv8 MALTOOLIGOSYL
TREHALOSE SYNTHASE

(Sulfolobus
acidocaldarius) 		PF00128
(Alpha-amylase)
PF09196
(DUF1953) 		4 LEU A 163
LEU A 127
LEU A 174
ILE A 125
 None
 0.93A 4okwA-1iv8A:
3.5		 4okwA-1iv8A:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 ASN A1163
LEU A1149
LEU A1116
ILE A1178
 None
 1.04A 4okwA-1jl5A:
0.0		 4okwA-1jl5A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lss TRK SYSTEM POTASSIUM
UPTAKE PROTEIN TRKA
HOMOLOG

(Methanocaldococcus
jannaschii) 		PF02254
(TrkA_N) 		4 LEU A  80
ASN A  79
LEU A  58
ILE A  29
 None
 1.02A 4okwA-1lssA:
undetectable		 4okwA-1lssA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lth L-LACTATE
DEHYDROGENASE (T-
AND R- STATE
TETRAMER COMPLEX)

(Bifidobacterium
longum) 		no annotation 4 LEU T 152
ASN T 151
LEU T  22
ILE T 248
 None
 0.81A 4okwA-1lthT:
undetectable		 4okwA-1lthT:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n0w BREAST CANCER TYPE 2
SUSCEPTIBILITY
PROTEIN
DNA REPAIR PROTEIN
RAD51 HOMOLOG 1

(Homo sapiens) 		PF00634
(BRCA2)
PF08423
(Rad51) 		4 LEU A 204
LEU B1539
MET A 211
LEU B1545
 None
 1.03A 4okwA-1n0wA:
undetectable		 4okwA-1n0wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n2m PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE

(Methanocaldococcus
jannaschii) 		PF01862
(PvlArgDC) 		4 LEU A  39
ASN A  40
LEU A  64
MET A  69
 None
 1.00A 4okwA-1n2mA:
undetectable		 4okwA-1n2mA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7d LYSOSOMAL
ALPHA-MANNOSIDASE

(Bos taurus) 		PF07748
(Glyco_hydro_38C) 		4 LEU E 956
LEU E 992
LEU E 903
ILE E 990
 None
 0.99A 4okwA-1o7dE:
undetectable		 4okwA-1o7dE:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7x CITRATE SYNTHASE

(Sulfolobus
solfataricus) 		PF00285
(Citrate_synt) 		4 LEU A  18
LEU A  38
LEU A 340
ILE A  35
 None
 1.03A 4okwA-1o7xA:
undetectable		 4okwA-1o7xA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2

(Synechocystis
sp. PCC 6803) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 ASN A1300
LEU A1284
MET A1337
ILE A1257
 None
 1.03A 4okwA-1ofeA:
undetectable		 4okwA-1ofeA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans) 		PF01331
(mRNA_cap_enzyme)
PF03919
(mRNA_cap_C) 		4 LEU A 239
LEU A 147
MET A 199
LEU A 159
 G  A1167 (-4.5A)
None
None
None
 1.01A 4okwA-1p16A:
undetectable		 4okwA-1p16A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q14 HST2 PROTEIN

(Saccharomyces
cerevisiae) 		PF02146
(SIR2) 		4 LEU A 102
MET A  19
LEU A 277
ILE A  35
 None
 0.91A 4okwA-1q14A:
undetectable		 4okwA-1q14A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qvr CLPB PROTEIN

(Thermus
thermophilus) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 LEU A 786
LEU A 808
LEU A 773
ILE A 765
 None
None
None
ANP  A 911 (-4.1A)
 1.03A 4okwA-1qvrA:
undetectable		 4okwA-1qvrA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6m RIBONUCLEASE PH

(Pseudomonas
aeruginosa) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		4 LEU A  12
MET A 218
LEU A 176
ILE A  15
 None
 0.99A 4okwA-1r6mA:
undetectable		 4okwA-1r6mA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN

(Rhinovirus B) 		PF00073
(Rhv) 		4 ASN 2 190
LEU 3  52
LEU 3 207
ILE 2 225
 None
 1.03A 4okwA-1rhi2:
undetectable		 4okwA-1rhi2:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sez PROTOPORPHYRINOGEN
OXIDASE,
MITOCHONDRIAL

(Nicotiana
tabacum) 		PF01593
(Amino_oxidase) 		4 LEU A 473
ASN A 468
LEU A 450
ILE A 453
 None
FAD  A 600 (-4.4A)
None
None
 0.83A 4okwA-1sezA:
undetectable		 4okwA-1sezA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ska 3-PHYTASE A

(Aspergillus
fumigatus) 		PF00328
(His_Phos_2) 		4 LEU A 402
LEU A 300
LEU A 410
ILE A 345
 None
 0.98A 4okwA-1skaA:
undetectable		 4okwA-1skaA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1taq TAQ DNA POLYMERASE

(Thermus
aquaticus) 		PF00476
(DNA_pol_A)
PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N)
PF09281
(Taq-exonuc) 		4 LEU A 581
MET A 779
MET A 765
LEU A 574
 None
 1.03A 4okwA-1taqA:
undetectable		 4okwA-1taqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uik ALPHA PRIME SUBUNIT
OF BETA-CONGLYCININ

(Glycine max) 		PF00190
(Cupin_1) 		4 LEU A 181
LEU A 263
LEU A 171
ILE A 265
 None
 0.90A 4okwA-1uikA:
undetectable		 4okwA-1uikA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukv GTP-BINDING PROTEIN
YPT1

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		4 ASN Y  16
MET Y 145
LEU Y 103
ILE Y  73
 None
 0.89A 4okwA-1ukvY:
undetectable		 4okwA-1ukvY:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vgm 378AA LONG
HYPOTHETICAL CITRATE
SYNTHASE

(Sulfurisphaera
tokodaii) 		PF00285
(Citrate_synt) 		4 LEU A  19
LEU A  39
LEU A 341
ILE A  36
 None
 1.04A 4okwA-1vgmA:
undetectable		 4okwA-1vgmA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vr0 PROBABLE
2-PHOSPHOSULFOLACTAT
E PHOSPHATASE

(Clostridium
acetobutylicum) 		PF04029
(2-ph_phosp) 		4 LEU A 124
ASN A 125
MET A  86
ILE A 234
 None
 0.91A 4okwA-1vr0A:
undetectable		 4okwA-1vr0A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wrb DJVLGB

(Dugesia
japonica) 		PF00270
(DEAD) 		4 LEU A 265
MET A 347
LEU A 341
ILE A 218
 None
 1.03A 4okwA-1wrbA:
undetectable		 4okwA-1wrbA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhn CELLULAR REPRESSOR
OF E1A-STIMULATED
GENES

(Homo sapiens) 		PF13883
(Pyrid_oxidase_2) 		4 LEU A 156
MET A  91
LEU A  55
ILE A 130
 None
 0.86A 4okwA-1xhnA:
undetectable		 4okwA-1xhnA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8p [PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 3

(Homo sapiens) 		PF02518
(HATPase_c)
PF10436
(BCDHK_Adom3) 		4 ASN A 166
LEU A 109
LEU A  49
ILE A 113
 None
 1.05A 4okwA-1y8pA:
undetectable		 4okwA-1y8pA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx2 AMINOMETHYLTRANSFERA
SE

(Bacillus
subtilis) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 LEU A 109
MET A  70
LEU A  98
ILE A 141
 None
 0.91A 4okwA-1yx2A:
undetectable		 4okwA-1yx2A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z85 HYPOTHETICAL PROTEIN
TM1380

(Thermotoga
maritima) 		PF04452
(Methyltrans_RNA) 		4 LEU A 210
LEU A 166
LEU A 162
ILE A 151
 None
 1.03A 4okwA-1z85A:
undetectable		 4okwA-1z85A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrm L-2-HALOACID
DEHALOGENASE

(Pseudomonas sp.
YL) 		PF13419
(HAD_2) 		4 LEU A 172
LEU A  15
LEU A 107
ILE A 116
 None
 1.03A 4okwA-1zrmA:
undetectable		 4okwA-1zrmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a4v PEROXIREDOXIN DOT5

(Saccharomyces
cerevisiae) 		PF00578
(AhpC-TSA) 		4 LEU A  75
ASN A  76
LEU A  84
ILE A  87
 None
 0.83A 4okwA-2a4vA:
undetectable		 4okwA-2a4vA:
22.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens) 		PF00104
(Hormone_recep) 		6 LEU A 704
ASN A 705
MET A 749
MET A 787
LEU A 873
ILE A 898
 BHM  A   1 (-4.0A)
BHM  A   1 (-3.6A)
BHM  A   1 (-4.3A)
BHM  A   1 (-3.6A)
BHM  A   1 (-4.4A)
None
 0.39A 4okwA-2ax9A:
41.9		 4okwA-2ax9A:
99.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayn UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 14

(Homo sapiens) 		PF00443
(UCH) 		4 LEU A 319
ASN A 413
LEU A 478
LEU A 352
 None
 0.98A 4okwA-2aynA:
undetectable		 4okwA-2aynA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b1w CASPASE RECRUITMENT
DOMAIN PROTEIN 4

(Homo sapiens) 		PF00619
(CARD) 		4 LEU A  40
ASN A  43
LEU A  23
ILE A  20
 None
 0.95A 4okwA-2b1wA:
undetectable		 4okwA-2b1wA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b42 XYLANASE INHIBITOR-I

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 LEU A 243
LEU A 238
MET A 312
LEU A 348
 None
 0.87A 4okwA-2b42A:
undetectable		 4okwA-2b42A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bde CYTOSOLIC IMP-GMP
SPECIFIC
5'-NUCLEOTIDASE

(Legionella
pneumophila) 		PF05761
(5_nucleotid) 		4 LEU A 299
LEU A 195
MET A 431
ILE A 199
 None
 0.71A 4okwA-2bdeA:
undetectable		 4okwA-2bdeA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdq COPPER HOMEOSTASIS
PROTEIN CUTC

(Streptococcus
agalactiae) 		PF03932
(CutC) 		4 LEU A  73
ASN A  71
LEU A 112
ILE A  97
 None
 1.01A 4okwA-2bdqA:
undetectable		 4okwA-2bdqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2be4 HYPOTHETICAL PROTEIN
LOC449832

(Danio rerio) 		PF13202
(EF-hand_5)
PF13499
(EF-hand_7) 		4 LEU A 182
LEU A 268
MET A 107
LEU A 167
 None
 1.03A 4okwA-2be4A:
undetectable		 4okwA-2be4A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bg9 ACETYLCHOLINE
RECEPTOR PROTEIN,
GAMMA CHAIN

(Torpedo
marmorata) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 LEU E  49
ASN E  94
LEU E  34
ILE E 208
 None
 1.05A 4okwA-2bg9E:
undetectable		 4okwA-2bg9E:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bnh RIBONUCLEASE
INHIBITOR

(Sus scrofa) 		PF13516
(LRR_6) 		4 LEU A  92
ASN A 118
LEU A 142
LEU A  85
 None
 1.03A 4okwA-2bnhA:
undetectable		 4okwA-2bnhA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2chq REPLICATION FACTOR C
SMALL SUBUNIT

(Archaeoglobus
fulgidus) 		PF00004
(AAA)
PF08542
(Rep_fac_C) 		4 LEU A 289
LEU A 239
MET A 231
LEU A 310
 None
 0.96A 4okwA-2chqA:
undetectable		 4okwA-2chqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ckh SENTRIN-SPECIFIC
PROTEASE 1

(Homo sapiens) 		PF02902
(Peptidase_C48) 		4 LEU A 466
LEU A 536
MET A 626
ILE A 528
 None
 1.03A 4okwA-2ckhA:
undetectable		 4okwA-2ckhA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4y FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 1

(Salmonella
enterica) 		no annotation 4 ASN A 309
LEU A 116
LEU A 139
ILE A 433
 None
 0.96A 4okwA-2d4yA:
undetectable		 4okwA-2d4yA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfs MYOSIN-5A

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ) 		4 LEU A 277
LEU A 411
MET A 305
ILE A 407
 None
 1.01A 4okwA-2dfsA:
undetectable		 4okwA-2dfsA:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dg0 DRP35

(Staphylococcus
aureus) 		PF08450
(SGL) 		4 ASN A  51
LEU A 309
LEU A 294
ILE A  71
 None
 1.02A 4okwA-2dg0A:
undetectable		 4okwA-2dg0A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpy FLAGELLUM-SPECIFIC
ATP SYNTHASE

(Salmonella
enterica) 		PF00006
(ATP-synt_ab) 		4 LEU A 424
LEU A 169
LEU A 390
ILE A 368
 None
 0.97A 4okwA-2dpyA:
undetectable		 4okwA-2dpyA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fm8 CELL INVASION
PROTEIN SIPA
SURFACE PRESENTATION
OF ANTIGENS PROTEIN
SPAK

(Salmonella
enterica) 		PF03519
(Invas_SpaK)
PF09052
(SipA) 		4 LEU A 119
ASN A 120
LEU A  40
LEU C  31
 None
 1.00A 4okwA-2fm8A:
undetectable		 4okwA-2fm8A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fwr DNA REPAIR PROTEIN
RAD25

(Archaeoglobus
fulgidus) 		PF04851
(ResIII)
PF16203
(ERCC3_RAD25_C) 		4 LEU A 196
LEU A 224
LEU A 204
ILE A 113
 None
 1.04A 4okwA-2fwrA:
undetectable		 4okwA-2fwrA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2go2 KUNITZ-TYPE SERINE
PROTEASE INHIBITOR
BBKI

(Bauhinia
bauhinioides) 		PF00197
(Kunitz_legume) 		4 LEU A  63
ASN A  14
LEU A 109
ILE A  76
 None
EDO  A 700 (-3.3A)
None
None
 0.92A 4okwA-2go2A:
undetectable		 4okwA-2go2A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ie8 PHOSPHOGLYCERATE
KINASE

(Thermus
caldophilus) 		PF00162
(PGK) 		4 LEU A 212
LEU A 226
MET A 218
LEU A 246
 None
 1.01A 4okwA-2ie8A:
undetectable		 4okwA-2ie8A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iw0 CHITIN DEACETYLASE

(Colletotrichum
lindemuthianum) 		PF01522
(Polysacc_deac_1) 		4 LEU A 168
ASN A 167
LEU A  46
ILE A 164
 None
 1.04A 4okwA-2iw0A:
undetectable		 4okwA-2iw0A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j1q ARGININE KINASE

(Trypanosoma
cruzi) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		4 LEU A  82
MET A  51
LEU A  27
ILE A  86
 None
 0.97A 4okwA-2j1qA:
undetectable		 4okwA-2j1qA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jqd ACIDIC LEUCINE-RICH
NUCLEAR
PHOSPHOPROTEIN 32
FAMILY MEMBER A

(Mus musculus) 		PF14580
(LRR_9) 		4 ASN A  74
LEU A  80
LEU A  69
ILE A 100
 None
 0.98A 4okwA-2jqdA:
undetectable		 4okwA-2jqdA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE

(Escherichia
virus N4) 		no annotation 4 ASN A 617
MET A 569
LEU A 611
ILE A 654
 None
 1.00A 4okwA-2po4A:
undetectable		 4okwA-2po4A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pts ADENYLOSUCCINATE
LYASE

(Escherichia
coli) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		4 ASN A 345
LEU A 135
LEU A  32
ILE A 350
 None
 0.92A 4okwA-2ptsA:
undetectable		 4okwA-2ptsA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qmo DETHIOBIOTIN
SYNTHETASE

(Helicobacter
pylori) 		PF13500
(AAA_26) 		4 LEU A 121
ASN A 130
LEU A 138
LEU A 168
 None
 0.86A 4okwA-2qmoA:
undetectable		 4okwA-2qmoA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qne PUTATIVE
METHYLTRANSFERASE

(Desulfitobacterium
hafniense) 		PF06253
(MTTB) 		4 LEU A 344
MET A 354
LEU A 229
ILE A 225
 None
EDO  A 483 (-3.5A)
EDO  A 478 (-4.7A)
None
 1.04A 4okwA-2qneA:
undetectable		 4okwA-2qneA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qww TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY

(Listeria
monocytogenes) 		PF12802
(MarR_2) 		4 LEU A  43
ASN A  47
LEU A  83
ILE A  55
 None
 1.04A 4okwA-2qwwA:
undetectable		 4okwA-2qwwA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9y ALPHA-2-ANTIPLASMIN

(Mus musculus) 		PF00079
(Serpin) 		4 ASN A 206
LEU A  93
LEU A 121
ILE A 139
 None
 0.94A 4okwA-2r9yA:
undetectable		 4okwA-2r9yA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wnt RIBOSOMAL PROTEIN S6
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 553
ASN A 471
LEU A 536
MET A 607
 None
 1.03A 4okwA-2wntA:
undetectable		 4okwA-2wntA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wul GLUTAREDOXIN RELATED
PROTEIN 5

(Homo sapiens) 		PF00462
(Glutaredoxin) 		4 LEU A  77
LEU A 147
MET A 128
LEU A 138
 None
 1.01A 4okwA-2wulA:
undetectable		 4okwA-2wulA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wyh ALPHA-MANNOSIDASE

(Streptococcus
pyogenes) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 LEU A 780
LEU A 562
LEU A 648
ILE A 652
 None
 0.88A 4okwA-2wyhA:
undetectable		 4okwA-2wyhA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x05 EXO-BETA-D-GLUCOSAMI
NIDASE

(Amycolatopsis
orientalis) 		PF00703
(Glyco_hydro_2)
PF02837
(Glyco_hydro_2_N) 		4 LEU A 238
ASN A 239
LEU A 292
LEU A 295
 None
 0.92A 4okwA-2x05A:
undetectable		 4okwA-2x05A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xot AMPHOTERIN-INDUCED
PROTEIN 1

(Mus musculus) 		PF07679
(I-set)
PF13855
(LRR_8) 		4 LEU A 129
LEU A 165
LEU A 122
ILE A 170
 None
 0.97A 4okwA-2xotA:
undetectable		 4okwA-2xotA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b5q PUTATIVE SULFATASE
YIDJ

(Bacteroides
thetaiotaomicron) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 LEU A  71
LEU A 355
LEU A 338
ILE A 353
 None
EDO  A 503 (-4.4A)
None
EDO  A 503 (-3.7A)
 0.97A 4okwA-3b5qA:
undetectable		 4okwA-3b5qA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cjn TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY

(Ruegeria
pomeroyi) 		PF01047
(MarR) 		4 LEU A 144
ASN A 148
MET A 131
ILE A 154
 None
 1.04A 4okwA-3cjnA:
undetectable		 4okwA-3cjnA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cky 2-HYDROXYMETHYL
GLUTARATE
DEHYDROGENASE

(Eubacterium
barkeri) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 LEU A 200
LEU A 188
LEU A 194
ILE A 227
 None
 1.04A 4okwA-3ckyA:
undetectable		 4okwA-3ckyA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides) 		PF03562
(MltA)
PF06725
(3D) 		4 ASN A 287
LEU A 272
LEU A 214
ILE A 268
 None
 0.99A 4okwA-3czbA:
undetectable		 4okwA-3czbA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d36 SPORULATION KINASE B

(Geobacillus
stearothermophilus) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		4 ASN A 320
MET A 357
LEU A 365
ILE A 389
 None
ADP  A 500 (-3.6A)
ADP  A 500 (-4.3A)
None
 1.05A 4okwA-3d36A:
undetectable		 4okwA-3d36A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbg PUTATIVE CYTOCHROME
P450

(Streptomyces
coelicolor) 		PF00067
(p450) 		4 LEU A 226
LEU A 245
LEU A 272
ILE A 264
 None
 0.93A 4okwA-3dbgA:
1.8		 4okwA-3dbgA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dcm UNCHARACTERIZED
PROTEIN TM_1570

(Thermotoga
maritima) 		PF09936
(Methyltrn_RNA_4) 		4 ASN X  28
LEU X   9
LEU X  87
ILE X  34
 None
 0.97A 4okwA-3dcmX:
undetectable		 4okwA-3dcmX:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE

(Bacillus cereus) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 189
LEU A 281
LEU A 260
ILE A 290
 None
 1.01A 4okwA-3dhvA:
undetectable		 4okwA-3dhvA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF14710
(Nitr_red_alph_N) 		4 LEU A 214
MET A 727
LEU A 716
ILE A 191
 None
 0.96A 4okwA-3egwA:
undetectable		 4okwA-3egwA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f9i 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE

(Rickettsia
prowazekii) 		PF13561
(adh_short_C2) 		4 LEU A 114
ASN A 115
LEU A  10
ILE A 171
 None
 1.01A 4okwA-3f9iA:
undetectable		 4okwA-3f9iA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fed GLUTAMATE
CARBOXYPEPTIDASE III

(Homo sapiens) 		PF02225
(PA)
PF04253
(TFR_dimer)
PF04389
(Peptidase_M28) 		4 LEU A 577
LEU A  51
LEU A 467
ILE A  47
 None
 1.03A 4okwA-3fedA:
undetectable		 4okwA-3fedA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0i EPOXIDE HYDROLASE

(Aspergillus
niger) 		PF06441
(EHN) 		4 LEU A 213
ASN A 214
LEU A 114
ILE A 127
 None
 0.95A 4okwA-3g0iA:
undetectable		 4okwA-3g0iA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g4f (+)-DELTA-CADINENE
SYNTHASE ISOZYME XC1

(Gossypium
arboreum) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ASN A 373
LEU A 348
MET A 295
ILE A 326
 None
 0.97A 4okwA-3g4fA:
undetectable		 4okwA-3g4fA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gku PROBABLE RNA-BINDING
PROTEIN

([Clostridium]
symbiosum) 		PF01424
(R3H)
PF13083
(KH_4)
PF14804
(Jag_N) 		4 ASN A 153
LEU A 182
MET A 170
LEU A 147
 None
 1.01A 4okwA-3gkuA:
undetectable		 4okwA-3gkuA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gv0 TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY

(Agrobacterium
fabrum) 		PF13377
(Peripla_BP_3) 		4 LEU A  71
LEU A 313
LEU A 308
ILE A 316
 None
 1.05A 4okwA-3gv0A:
undetectable		 4okwA-3gv0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyu NUCLEAR HORMONE
RECEPTOR OF THE
STEROID/THYROID
HORMONE RECEPTORS
SUPERFAMILY

(Strongyloides
stercoralis) 		PF00104
(Hormone_recep) 		4 LEU A 657
ASN A 655
LEU A 694
ILE A 714
 None
 0.89A 4okwA-3gyuA:
17.9		 4okwA-3gyuA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icq EXPORTIN-T

(Schizosaccharomyces
pombe) 		PF08389
(Xpo1) 		4 ASN T 258
MET T 233
LEU T 273
ILE T 309
 None
 1.02A 4okwA-3icqT:
undetectable		 4okwA-3icqT:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3imk PUTATIVE MOLYBDENUM
CARRIER PROTEIN

(Syntrophus
aciditrophicus) 		PF12694
(MoCo_carrier) 		4 ASN A 132
LEU A 152
LEU A  23
ILE A  79
 None
 0.99A 4okwA-3imkA:
undetectable		 4okwA-3imkA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 LEU A 908
LEU A1057
MET A 937
ILE A1063
 None
 1.03A 4okwA-3jb9A:
undetectable		 4okwA-3jb9A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k69 PUTATIVE
TRANSCRIPTION
REGULATOR

(Lactobacillus
plantarum) 		PF02082
(Rrf2) 		4 LEU A  18
LEU A  48
MET A  76
LEU A  69
 None
 1.05A 4okwA-3k69A:
undetectable		 4okwA-3k69A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k94 THIAMIN
PYROPHOSPHOKINASE

(Geobacillus
thermodenitrificans) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		4 LEU A 117
LEU A  98
LEU A 133
ILE A  96
 None
None
None
CSO  A  95 ( 3.9A)
 1.01A 4okwA-3k94A:
undetectable		 4okwA-3k94A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l06 N-ACETYLORNITHINE
CARBAMOYLTRANSFERASE

(Xanthomonas
campestris) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A   7
ASN A   8
LEU A 153
ILE A 195
 None
 0.92A 4okwA-3l06A:
undetectable		 4okwA-3l06A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6c 60 KDA CHAPERONIN 1

(Mycobacterium
tuberculosis) 		PF00118
(Cpn60_TCP1) 		4 LEU A 269
ASN A 263
LEU A 257
LEU A 231
 None
 1.04A 4okwA-3m6cA:
undetectable		 4okwA-3m6cA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6m RPFF PROTEIN
SENSORY/REGULATORY
PROTEIN RPFC

(Xanthomonas
campestris) 		PF00072
(Response_reg)
PF00378
(ECH_1) 		4 LEU D 521
ASN D 519
LEU D 498
LEU A 163
 None
 1.01A 4okwA-3m6mD:
undetectable		 4okwA-3m6mD:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n23 SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		4 ASN A 776
LEU A 784
LEU A 795
ILE A 320
 None
 0.98A 4okwA-3n23A:
undetectable		 4okwA-3n23A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9i TRYPTOPHANYL-TRNA
SYNTHETASE

(Yersinia pestis) 		PF00579
(tRNA-synt_1b) 		5 LEU A  37
ASN A  32
LEU A 297
LEU A  78
ILE A 219
 None
 1.40A 4okwA-3n9iA:
undetectable		 4okwA-3n9iA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ncy ADIC

(Salmonella
enterica) 		PF13520
(AA_permease_2) 		4 LEU A 197
ASN A 198
LEU A 362
ILE A 359
 None
 1.04A 4okwA-3ncyA:
undetectable		 4okwA-3ncyA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nd6 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Enterococcus
faecalis) 		PF01467
(CTP_transf_like) 		4 LEU A 147
ASN A  16
LEU A  54
ILE A  22
 None
 0.97A 4okwA-3nd6A:
undetectable		 4okwA-3nd6A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oht P38A

(Salmo salar) 		PF00069
(Pkinase) 		4 LEU A 217
LEU A 136
LEU A 157
ILE A 207
 None
 0.93A 4okwA-3ohtA:
undetectable		 4okwA-3ohtA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op7 AMINOTRANSFERASE
CLASS I AND II

(Streptococcus
suis) 		PF00155
(Aminotran_1_2) 		4 LEU A 124
LEU A 243
LEU A  94
ILE A 214
 None
 1.04A 4okwA-3op7A:
undetectable		 4okwA-3op7A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p01 TWO-COMPONENT
RESPONSE REGULATOR

(Nostoc sp. PCC
7120) 		PF13185
(GAF_2) 		4 LEU A 289
LEU A 228
LEU A 281
ILE A 244
 None
 1.04A 4okwA-3p01A:
undetectable		 4okwA-3p01A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pz6 LEUCYL-TRNA
SYNTHETASE

(Giardia
intestinalis) 		PF00133
(tRNA-synt_1) 		4 LEU A 382
ASN A 383
LEU A 333
ILE A 394
 None
 1.04A 4okwA-3pz6A:
undetectable		 4okwA-3pz6A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qm1 CINNAMOYL ESTERASE

(Lactobacillus
johnsonii) 		PF12146
(Hydrolase_4) 		4 ASN A  89
LEU A 102
LEU A 118
ILE A 100
 None
 1.05A 4okwA-3qm1A:
undetectable		 4okwA-3qm1A:
19.66