SIMILAR PATTERNS OF AMINO ACIDS FOR 4OK1_A_198A1001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h1y D-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE


(Oryza sativa)
PF00834
(Ribul_P_3_epim)
4 ASN A 100
MET A 113
LEU A  70
ILE A  94
None
1.05A 4ok1A-1h1yA:
undetectable
4ok1A-1h1yA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ipf TROPINONE
REDUCTASE-II


(Datura
stramonium)
PF13561
(adh_short_C2)
4 LEU A  91
ASN A  93
LEU A  76
ILE A 117
None
None
None
NDP  A 261 ( 4.1A)
1.00A 4ok1A-1ipfA:
undetectable
4ok1A-1ipfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhd SULFATE
ADENYLYLTRANSFERASE


(Sulfur-oxidizing
endosymbiont of
Riftia
pachyptila)
PF01747
(ATP-sulfurylase)
PF14306
(PUA_2)
4 LEU A  55
MET A 131
LEU A  84
ILE A 117
None
0.90A 4ok1A-1jhdA:
undetectable
4ok1A-1jhdA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN


(Homo sapiens)
PF00023
(Ank)
PF12796
(Ank_2)
4 LEU A 286
LEU A 238
HIS A 239
ILE A 273
None
0.89A 4ok1A-1k1bA:
undetectable
4ok1A-1k1bA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m72 CASPASE-1

(Spodoptera
frugiperda)
PF00656
(Peptidase_C14)
4 LEU A 240
MET A  55
LEU A 291
ILE A 212
None
0.98A 4ok1A-1m72A:
undetectable
4ok1A-1m72A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE


(Homo sapiens)
PF02898
(NO_synthase)
4 LEU A 292
ASN A 245
LEU A 304
ILE A 215
None
1.07A 4ok1A-1m9qA:
undetectable
4ok1A-1m9qA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ukv GTP-BINDING PROTEIN
YPT1


(Saccharomyces
cerevisiae)
PF00071
(Ras)
4 ASN Y  16
MET Y 145
LEU Y 103
ILE Y  73
None
0.92A 4ok1A-1ukvY:
undetectable
4ok1A-1ukvY:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzg MAJOR ENVELOPE
PROTEIN E


(Dengue virus)
PF00869
(Flavi_glycoprot)
PF02832
(Flavi_glycop_C)
4 LEU A  25
MET A 287
LEU A  41
HIS A 144
None
0.97A 4ok1A-1uzgA:
undetectable
4ok1A-1uzgA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vrn PHOTOSYNTHETIC
REACTION CENTER
CYTOCHROME C SUBUNIT


(Blastochloris
viridis)
PF02276
(CytoC_RC)
4 LEU C 282
ASN C 278
HIS C 124
ILE C 271
HEM  C 402 ( 4.5A)
None
HEM  C 404 (-3.2A)
HEM  C 403 (-4.5A)
1.05A 4ok1A-1vrnC:
undetectable
4ok1A-1vrnC:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wst MULTIPLE SUBSTRATE
AMINOTRANSFERASE


(Thermococcus
profundus)
PF00155
(Aminotran_1_2)
4 LEU A 326
MET A 412
MET A 358
LEU A 349
None
0.99A 4ok1A-1wstA:
undetectable
4ok1A-1wstA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1q TRYPTOPHAN SYNTHASE
BETA CHAIN


(Thermus
thermophilus)
PF00291
(PALP)
4 LEU A  70
ASN A 111
LEU A  18
ILE A 260
None
None
None
CL  A1001 (-4.0A)
1.06A 4ok1A-1x1qA:
undetectable
4ok1A-1x1qA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhn CELLULAR REPRESSOR
OF E1A-STIMULATED
GENES


(Homo sapiens)
PF13883
(Pyrid_oxidase_2)
4 MET A  91
LEU A  55
HIS A 139
ILE A 137
None
0.97A 4ok1A-1xhnA:
undetectable
4ok1A-1xhnA:
19.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ax9 ANDROGEN RECEPTOR

(Homo sapiens)
PF00104
(Hormone_recep)
8 LEU A 701
ASN A 705
MET A 745
MET A 749
MET A 787
LEU A 873
HIS A 874
ILE A 898
None
BHM  A   1 (-3.6A)
BHM  A   1 (-3.9A)
BHM  A   1 (-4.3A)
BHM  A   1 (-3.6A)
BHM  A   1 (-4.4A)
None
None
0.37A 4ok1A-2ax9A:
41.1
4ok1A-2ax9A:
99.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bku IMPORTIN BETA-1
SUBUNIT


(Saccharomyces
cerevisiae)
PF03810
(IBN_N)
PF13513
(HEAT_EZ)
4 MET B 162
MET B 139
LEU B 104
ILE B  59
None
0.97A 4ok1A-2bkuB:
undetectable
4ok1A-2bkuB:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dep THERMOSTABLE
CELLOXYLANASE


([Clostridium]
stercorarium)
PF00331
(Glyco_hydro_10)
4 LEU A 287
ASN A 289
LEU A 242
ILE A 275
None
0.88A 4ok1A-2depA:
undetectable
4ok1A-2depA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ess ACYL-ACP
THIOESTERASE


(Bacteroides
thetaiotaomicron)
PF01643
(Acyl-ACP_TE)
4 LEU A  52
LEU A 129
HIS A 130
ILE A 138
None
1.03A 4ok1A-2essA:
undetectable
4ok1A-2essA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR


(Escherichia
coli)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF)
4 LEU A 754
MET A 616
LEU A 725
ILE A 680
None
0.98A 4ok1A-2eyqA:
undetectable
4ok1A-2eyqA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzs IROE PROTEIN

(Escherichia
coli)
PF00756
(Esterase)
4 MET A 242
LEU A 239
HIS A 238
ILE A 302
None
1.06A 4ok1A-2gzsA:
undetectable
4ok1A-2gzsA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hng HYPOTHETICAL PROTEIN

(Streptococcus
pneumoniae)
PF06619
(DUF1149)
4 LEU A   7
ASN A  78
LEU A  91
ILE A  58
None
1.02A 4ok1A-2hngA:
undetectable
4ok1A-2hngA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5b TYROSYL-TRNA
SYNTHETASE


(Acanthamoeba
polyphaga
mimivirus)
PF00579
(tRNA-synt_1b)
4 LEU A 182
ASN A 190
MET A 127
ILE A 204
LEU  A 182 (-0.6A)
ASN  A 190 ( 0.6A)
MET  A 127 ( 0.0A)
ILE  A 204 ( 0.7A)
0.87A 4ok1A-2j5bA:
undetectable
4ok1A-2j5bA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jx3 PROTEIN DEK

(Homo sapiens)
PF02037
(SAP)
4 LEU A 106
LEU A  32
HIS A  33
ILE A   3
None
1.03A 4ok1A-2jx3A:
undetectable
4ok1A-2jx3A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nn3 CASPASE-1

(Spodoptera
frugiperda)
PF00656
(Peptidase_C14)
4 LEU C 240
MET C  55
LEU C 291
ILE C 212
None
0.94A 4ok1A-2nn3C:
undetectable
4ok1A-2nn3C:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oda HYPOTHETICAL PROTEIN
PSPTO_2114


(Pseudomonas
syringae group
genomosp. 3)
no annotation 4 LEU A 117
MET A  77
LEU A  17
ILE A 173
None
1.00A 4ok1A-2odaA:
undetectable
4ok1A-2odaA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2po4 VIRION RNA
POLYMERASE


(Escherichia
virus N4)
no annotation 4 ASN A 617
MET A 569
LEU A 611
ILE A 654
None
1.01A 4ok1A-2po4A:
undetectable
4ok1A-2po4A:
13.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q3y ANCESTRAL CORTICIOD
RECEPTOR


(unidentified)
PF00104
(Hormone_recep)
5 ASN A  33
MET A  73
MET A 115
LEU A 201
ILE A 226
1CA  A 247 (-2.9A)
1CA  A 247 (-3.6A)
1CA  A 247 ( 3.7A)
1CA  A 247 ( 4.2A)
None
0.87A 4ok1A-2q3yA:
37.1
4ok1A-2q3yA:
59.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2q3y ANCESTRAL CORTICIOD
RECEPTOR


(unidentified)
PF00104
(Hormone_recep)
5 LEU A  29
ASN A  33
MET A  73
MET A 115
LEU A 201
1CA  A 247 ( 3.6A)
1CA  A 247 (-2.9A)
1CA  A 247 (-3.6A)
1CA  A 247 ( 3.7A)
1CA  A 247 ( 4.2A)
0.86A 4ok1A-2q3yA:
37.1
4ok1A-2q3yA:
59.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3au9 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE


(Plasmodium
falciparum)
PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C)
4 LEU A 252
MET A 464
LEU A 187
ILE A 177
None
1.05A 4ok1A-3au9A:
undetectable
4ok1A-3au9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2d CD180 ANTIGEN

(Homo sapiens)
PF00560
(LRR_1)
PF13855
(LRR_8)
4 LEU A  84
ASN A 111
HIS A  93
ILE A 114
None
1.02A 4ok1A-3b2dA:
undetectable
4ok1A-3b2dA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b95 EUCHROMATIC
HISTONE-LYSINE
N-METHYLTRANSFERASE
1


(Homo sapiens)
PF12796
(Ank_2)
PF13637
(Ank_4)
4 LEU A 860
LEU A 812
HIS A 813
ILE A 847
None
0.98A 4ok1A-3b95A:
undetectable
4ok1A-3b95A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d36 SPORULATION KINASE B

(Geobacillus
stearothermophilus)
PF00512
(HisKA)
PF02518
(HATPase_c)
4 ASN A 320
MET A 357
LEU A 365
ILE A 389
None
ADP  A 500 (-3.6A)
ADP  A 500 (-4.3A)
None
1.03A 4ok1A-3d36A:
undetectable
4ok1A-3d36A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dxo UNCHARACTERIZED
SNOAL-LIKE PROTEIN


(Agrobacterium
fabrum)
PF12680
(SnoaL_2)
4 LEU A  12
ASN A  16
MET A  53
MET A  42
None
None
None
PGE  A 121 ( 4.3A)
1.03A 4ok1A-3dxoA:
undetectable
4ok1A-3dxoA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA


(Homo sapiens)
PF00104
(Hormone_recep)
PF00105
(zf-C4)
4 MET D 463
LEU D 453
HIS D 449
ILE D 326
None
None
None
PLB  D 701 ( 4.5A)
0.97A 4ok1A-3dzuD:
18.1
4ok1A-3dzuD:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ew7 LMO0794 PROTEIN

(Listeria
monocytogenes)
PF13460
(NAD_binding_10)
4 LEU A 204
ASN A 205
LEU A  99
ILE A  87
None
0.96A 4ok1A-3ew7A:
undetectable
4ok1A-3ew7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5i PYRIMIDINE-SPECIFIC
RIBONUCLEOSIDE
HYDROLASE RIHA


(Escherichia
coli)
PF01156
(IU_nuc_hydro)
4 LEU A   6
LEU A 140
HIS A 141
ILE A 176
None
1.06A 4ok1A-3g5iA:
undetectable
4ok1A-3g5iA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gmg UNCHARACTERIZED
PROTEIN
RV1825/MT1873


(Mycobacterium
tuberculosis)
PF05949
(DUF881)
4 ASN A 202
MET A 184
MET A 249
LEU A 191
None
1.02A 4ok1A-3gmgA:
undetectable
4ok1A-3gmgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihy PHOSPHATIDYLINOSITOL
3-KINASE CATALYTIC
SUBUNIT TYPE 3


(Homo sapiens)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
4 LEU A 665
MET A 777
MET A 859
ILE A 650
None
0.99A 4ok1A-3ihyA:
undetectable
4ok1A-3ihyA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jbl NLR FAMILY CARD
DOMAIN-CONTAINING
PROTEIN 4


(Mus musculus)
no annotation 4 LEU K 847
ASN K 843
MET K 808
LEU K 787
None
0.97A 4ok1A-3jblK:
undetectable
4ok1A-3jblK:
15.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kba PROGESTERONE
RECEPTOR


(Homo sapiens)
PF00104
(Hormone_recep)
5 ASN A 719
MET A 759
MET A 801
LEU A 887
HIS A 888
WOW  A   1 (-3.3A)
WOW  A   1 (-3.7A)
WOW  A   1 (-4.2A)
WOW  A   1 (-4.0A)
None
1.09A 4ok1A-3kbaA:
34.8
4ok1A-3kbaA:
54.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kba PROGESTERONE
RECEPTOR


(Homo sapiens)
PF00104
(Hormone_recep)
5 LEU A 715
ASN A 719
MET A 759
MET A 801
HIS A 888
WOW  A   1 (-3.9A)
WOW  A   1 (-3.3A)
WOW  A   1 (-3.7A)
WOW  A   1 (-4.2A)
None
0.95A 4ok1A-3kbaA:
34.8
4ok1A-3kbaA:
54.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l3s ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN


(Ruegeria
pomeroyi)
PF00378
(ECH_1)
4 LEU A  10
MET A  98
LEU A 123
ILE A  63
None
1.07A 4ok1A-3l3sA:
undetectable
4ok1A-3l3sA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o6x GLUTAMINE SYNTHETASE

(Bacteroides
fragilis)
PF00120
(Gln-synt_C)
PF12437
(GSIII_N)
4 LEU A 303
ASN A 302
MET A  41
ILE A 168
None
0.92A 4ok1A-3o6xA:
undetectable
4ok1A-3o6xA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3olq UNIVERSAL STRESS
PROTEIN E


(Proteus
mirabilis)
PF00582
(Usp)
4 LEU A 298
LEU A   7
HIS A 109
ILE A 100
None
1.07A 4ok1A-3olqA:
undetectable
4ok1A-3olqA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9u TETX2 PROTEIN

(Bacteroides
thetaiotaomicron)
PF01494
(FAD_binding_3)
4 ASN A 168
LEU A 315
HIS A 314
ILE A 309
FAD  A 401 (-4.7A)
None
None
None
0.96A 4ok1A-3p9uA:
undetectable
4ok1A-3p9uA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q5e ATLASTIN-1

(Homo sapiens)
PF02263
(GBP)
4 ASN A 177
MET A  87
LEU A 297
ILE A 213
None
1.03A 4ok1A-3q5eA:
undetectable
4ok1A-3q5eA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg1 CD180 MOLECULE

(Bos taurus)
PF00560
(LRR_1)
PF13855
(LRR_8)
4 LEU A  84
ASN A 111
HIS A  93
ILE A 114
None
0.97A 4ok1A-3rg1A:
undetectable
4ok1A-3rg1A:
16.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ry9 ANCESTRAL
GLUCOCORTICOID
RECEPTOR 1


(synthetic
construct)
PF00104
(Hormone_recep)
4 ASN A  33
MET A  73
LEU A 201
ILE A 226
1CA  A 249 (-3.0A)
1CA  A 249 (-3.9A)
1CA  A 249 ( 4.2A)
None
0.84A 4ok1A-3ry9A:
36.1
4ok1A-3ry9A:
54.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sip CASPASE

(Drosophila
melanogaster)
PF00656
(Peptidase_C14)
4 LEU B 202
MET A  15
LEU B 253
ILE B 174
None
0.96A 4ok1A-3sipB:
undetectable
4ok1A-3sipB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sir CASPASE

(Drosophila
melanogaster)
PF00656
(Peptidase_C14)
4 LEU A 202
MET A  15
LEU A 253
ILE A 174
None
0.96A 4ok1A-3sirA:
undetectable
4ok1A-3sirA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus)
PF13855
(LRR_8)
4 LEU A  84
ASN A 111
HIS A  93
ILE A 114
None
0.86A 4ok1A-3t6qA:
undetectable
4ok1A-3t6qA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uc9 INCREASED
RECOMBINATION
CENTERS PROTEIN 6


(Saccharomyces
cerevisiae)
no annotation 4 LEU A 166
LEU A  21
HIS A  18
ILE A  92
None
1.02A 4ok1A-3uc9A:
undetectable
4ok1A-3uc9A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bev COPPER EFFLUX ATPASE

(Legionella
pneumophila)
PF00122
(E1-E2_ATPase)
PF00702
(Hydrolase)
4 MET A 537
MET A 539
LEU A 438
ILE A 281
None
0.84A 4ok1A-4bevA:
undetectable
4ok1A-4bevA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cuk D-LACTATE
DEHYDROGENASE


(Salmonella
enterica)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 LEU A 255
LEU A 203
HIS A 204
ILE A 110
None
0.93A 4ok1A-4cukA:
undetectable
4ok1A-4cukA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans)
PF00067
(p450)
4 LEU A 381
LEU A 276
HIS A 273
ILE A 268
None
None
PEG  A 506 (-3.7A)
None
1.05A 4ok1A-4dxyA:
2.4
4ok1A-4dxyA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exj UNCHARACTERIZED
PROTEIN


(Lodderomyces
elongisporus)
PF00043
(GST_C)
PF13417
(GST_N_3)
4 ASN A 205
MET A  30
LEU A  16
ILE A 201
None
0.96A 4ok1A-4exjA:
undetectable
4ok1A-4exjA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hu3 OXYGEN SENSOR
PROTEIN DOSP


(Escherichia
coli)
PF00563
(EAL)
4 LEU A 636
MET A 690
MET A 654
LEU A 664
None
0.94A 4ok1A-4hu3A:
undetectable
4ok1A-4hu3A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxq ARGINASE-1

(Homo sapiens)
PF00491
(Arginase)
4 LEU A 216
LEU A 229
HIS A 228
ILE A 169
None
0.81A 4ok1A-4hxqA:
undetectable
4ok1A-4hxqA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l6u PUTATIVE
UNCHARACTERIZED
PROTEIN


(Archaeoglobus
fulgidus)
PF03787
(RAMPs)
4 LEU A 167
MET A  37
LEU A  10
ILE A 283
None
0.91A 4ok1A-4l6uA:
undetectable
4ok1A-4l6uA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8y PUTATIVE TRAP-TYPE
C4-DICARBOXYLATE
TRANSPORT SYSTEM,
BINDING PERIPLASMIC
PROTEIN (DCTP
SUBUNIT)


(Bradyrhizobium
sp. BTAi1)
PF03480
(DctP)
4 LEU A  76
MET A  44
LEU A 235
ILE A 125
None
1.01A 4ok1A-4n8yA:
undetectable
4ok1A-4n8yA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ng4 PHOSPHOGLYCERATE
KINASE


(Coxiella
burnetii)
PF00162
(PGK)
4 LEU A  94
MET A  29
LEU A  63
HIS A  62
None
0.97A 4ok1A-4ng4A:
undetectable
4ok1A-4ng4A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1o RIBONUCLEASE L

(Sus scrofa)
PF00069
(Pkinase)
PF06479
(Ribonuc_2-5A)
PF12796
(Ank_2)
PF13857
(Ank_5)
4 LEU A 108
LEU A  61
HIS A  62
ILE A  95
None
1.03A 4ok1A-4o1oA:
undetectable
4ok1A-4o1oA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4om7 TOLL-LIKE RECEPTOR 6

(Homo sapiens)
PF01582
(TIR)
4 ASN A 690
LEU A 673
HIS A 674
ILE A 684
None
1.06A 4ok1A-4om7A:
undetectable
4ok1A-4om7A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ou4 ALPHA/BETA HYDROLASE
FOLD-3 DOMAIN
PROTEIN


(Pseudomonas sp.
ECU1011)
PF07859
(Abhydrolase_3)
4 LEU A 290
ASN A 158
MET A 212
LEU A  91
None
1.01A 4ok1A-4ou4A:
undetectable
4ok1A-4ou4A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pue ENDO-1,4-BETA-XYLANA
SE


(Geobacillus
stearothermophilus)
PF00331
(Glyco_hydro_10)
4 LEU A 259
ASN A 261
LEU A 214
ILE A 247
None
0.87A 4ok1A-4pueA:
undetectable
4ok1A-4pueA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxe LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, LINKER,
VARIABLE LYMPHOCYTE
RECEPTOR B


(Eptatretus
burgeri;
Homo sapiens)
PF01462
(LRRNT)
PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8)
4 LEU A 247
ASN A 271
LEU A 232
ILE A 263
None
1.02A 4ok1A-4qxeA:
undetectable
4ok1A-4qxeA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rc6 ALDEHYDE
DECARBONYLASE


(Synechococcus
elongatus)
PF11266
(Ald_deCOase)
4 LEU B 108
MET B 180
LEU B  90
HIS B  91
None
1.05A 4ok1A-4rc6B:
undetectable
4ok1A-4rc6B:
24.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4udb MINERALOCORTICOID
RECEPTOR


(Homo sapiens)
PF00104
(Hormone_recep)
4 LEU A 766
ASN A 770
LEU A 938
ILE A 963
CV7  A1987 (-3.6A)
CV7  A1987 (-3.1A)
CV7  A1987 ( 3.9A)
None
0.64A 4ok1A-4udbA:
33.2
4ok1A-4udbA:
52.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4udb MINERALOCORTICOID
RECEPTOR


(Homo sapiens)
PF00104
(Hormone_recep)
4 LEU A 766
MET A 852
LEU A 938
ILE A 963
CV7  A1987 (-3.6A)
CV7  A1987 ( 3.7A)
CV7  A1987 ( 3.9A)
None
0.89A 4ok1A-4udbA:
33.2
4ok1A-4udbA:
52.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu9 GLUTAMINYL-PEPTIDE
CYCLOTRANSFERASE


(Homo sapiens)
PF04389
(Peptidase_M28)
4 LEU A 271
MET A 166
LEU A 247
ILE A 303
None
1.03A 4ok1A-4yu9A:
undetectable
4ok1A-4yu9A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zrs ESTERASE

(uncultured
bacterium)
PF07859
(Abhydrolase_3)
4 MET A 255
MET A 223
MET A 280
LEU A 258
None
0.99A 4ok1A-4zrsA:
undetectable
4ok1A-4zrsA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ck7 ADP-DEPENDENT
GLUCOKINASE


(Mus musculus)
PF04587
(ADP_PFK_GK)
4 LEU A 243
MET A 301
LEU A 296
HIS A 295
None
0.87A 4ok1A-5ck7A:
undetectable
4ok1A-5ck7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e78 BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE


(Bacillus
megaterium)
PF00067
(p450)
4 LEU A 133
MET A 145
LEU A 126
ILE A 453
None
1.02A 4ok1A-5e78A:
undetectable
4ok1A-5e78A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1p PTMO8

(Streptomyces
platensis)
PF13561
(adh_short_C2)
4 LEU A 171
ASN A 145
LEU A 132
ILE A  87
None
1.03A 4ok1A-5f1pA:
undetectable
4ok1A-5f1pA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9s SERINE--PYRUVATE
AMINOTRANSFERASE


(Homo sapiens)
PF00266
(Aminotran_5)
4 ASN A  72
MET A 230
LEU A 179
ILE A 220
None
0.96A 4ok1A-5f9sA:
undetectable
4ok1A-5f9sA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fm2 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET


(Homo sapiens)
PF07714
(Pkinase_Tyr)
4 LEU A 816
MET A 984
MET A 980
ILE A 890
None
0.82A 4ok1A-5fm2A:
undetectable
4ok1A-5fm2A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ftf TPR DOMAIN PROTEIN

(Bacteroides sp.
3_1_23)
PF05970
(PIF1)
4 LEU A 122
LEU A  67
HIS A  68
ILE A  78
None
0.93A 4ok1A-5ftfA:
undetectable
4ok1A-5ftfA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjv VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S


(Oryctolagus
cuniculus)
PF00520
(Ion_trans)
PF08763
(Ca_chan_IQ)
PF16905
(GPHH)
4 LEU A 472
ASN A 468
LEU A 512
ILE A 524
None
1.02A 4ok1A-5gjvA:
1.5
4ok1A-5gjvA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hly INHIBIN BETA A CHAIN

(Homo sapiens)
PF00019
(TGF_beta)
PF00688
(TGFb_propeptide)
4 MET A 399
MET A 401
LEU A  66
HIS A  67
None
0.97A 4ok1A-5hlyA:
undetectable
4ok1A-5hlyA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jm0 ALPHA-MANNOSIDASE,AL
PHA-MANNOSIDASE,ALPH
A-MANNOSIDASE


(Saccharomyces
cerevisiae)
PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid)
4 LEU A 497
ASN A 296
HIS A 626
ILE A 299
None
1.00A 4ok1A-5jm0A:
undetectable
4ok1A-5jm0A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m22 HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT
HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT


(Sphingomonas
sp. TTNP3)
no annotation 4 LEU A 148
MET B 174
LEU B 221
ILE A 121
None
0.89A 4ok1A-5m22A:
undetectable
4ok1A-5m22A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m5p PRE-MRNA-SPLICING
HELICASE BRR2


(Saccharomyces
cerevisiae)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63)
4 LEU A1511
LEU A1384
HIS A1387
ILE A1506
None
0.88A 4ok1A-5m5pA:
undetectable
4ok1A-5m5pA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mrw POTASSIUM-TRANSPORTI
NG ATPASE
POTASSIUM-BINDING
SUBUNIT


(Escherichia
coli)
PF03814
(KdpA)
4 LEU A 380
MET A  17
LEU A 284
ILE A 532
None
1.01A 4ok1A-5mrwA:
undetectable
4ok1A-5mrwA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwp MINERALOCORTICOID
RECEPTOR


(Homo sapiens)
no annotation 4 ASN A 770
MET A 852
LEU A 938
ILE A 963
ECV  A1101 (-3.1A)
ECV  A1101 (-3.7A)
ECV  A1101 ( 4.3A)
None
0.77A 4ok1A-5mwpA:
36.3
4ok1A-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwp MINERALOCORTICOID
RECEPTOR


(Homo sapiens)
no annotation 4 LEU A 766
ASN A 770
LEU A 938
ILE A 963
ECV  A1101 ( 3.9A)
ECV  A1101 (-3.1A)
ECV  A1101 ( 4.3A)
None
0.51A 4ok1A-5mwpA:
36.3
4ok1A-5mwpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npr UDP-N-ACETYLGLUCOSAM
INE--PEPTIDE
N-ACETYLGLUCOSAMINYL
TRANSFERASE 110 KDA
SUBUNIT


(Homo sapiens)
no annotation 4 LEU A 583
ASN A 630
MET A 664
LEU A 626
None
1.04A 4ok1A-5nprA:
undetectable
4ok1A-5nprA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sv9 BOR1P BORON
TRANSPORTER


(Saccharomyces
mikatae)
PF00955
(HCO3_cotransp)
4 LEU A 415
MET A 425
LEU A 361
HIS A 362
None
0.96A 4ok1A-5sv9A:
undetectable
4ok1A-5sv9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5swu PENTAFUNCTIONAL AROM
POLYPEPTIDE


(Aspergillus
fumigatus)
PF01487
(DHquinase_I)
4 ASN A1241
MET A1285
LEU A1252
ILE A1238
None
0.94A 4ok1A-5swuA:
undetectable
4ok1A-5swuA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tf0 GLYCOSYL HYDROLASE
FAMILY 3 N-TERMINAL
DOMAIN PROTEIN


(Bacteroides
intestinalis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
4 LEU A  77
ASN A  52
MET A 343
ILE A 296
None
0.97A 4ok1A-5tf0A:
undetectable
4ok1A-5tf0A:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w66 RNA POLYMERASE
I-SPECIFIC
TRANSCRIPTION
INITIATION FACTOR
RRN7


(Saccharomyces
cerevisiae)
no annotation 4 LEU P 119
LEU P 172
HIS P 171
ILE P 135
None
1.06A 4ok1A-5w66P:
undetectable
4ok1A-5w66P:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7k OXAG

(Penicillium
oxalicum)
no annotation 4 LEU A 146
MET A 108
LEU A  53
ILE A  35
None
1.03A 4ok1A-5w7kA:
undetectable
4ok1A-5w7kA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnp LEUCINE-RICH REPEAT
AND FIBRONECTIN
TYPE-III
DOMAIN-CONTAINING
PROTEIN 5


(Homo sapiens)
no annotation 4 LEU A 111
ASN A 133
LEU A 104
HIS A 105
None
None
None
SO4  A 414 ( 3.8A)
1.04A 4ok1A-5xnpA:
undetectable
4ok1A-5xnpA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi RIBOSOMAL PROTEIN
S15A
UNCHARACTERIZED
PROTEIN


(Trichomonas
vaginalis)
PF00333
(Ribosomal_S5)
PF00410
(Ribosomal_S8)
PF03719
(Ribosomal_S5_C)
4 LEU C 240
ASN W  70
LEU W  66
ILE W  14
None
0.96A 4ok1A-5xyiC:
undetectable
4ok1A-5xyiC:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b9g ATLASTIN-1

(Homo sapiens)
no annotation 4 ASN B 177
MET B  87
LEU B 297
ILE B 213
None
1.00A 4ok1A-6b9gB:
undetectable
4ok1A-6b9gB:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6by9 HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1


(Homo sapiens)
no annotation 4 LEU A 891
LEU A 843
HIS A 844
ILE A 878
None
0.97A 4ok1A-6by9A:
undetectable
4ok1A-6by9A:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byo VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
ALPHA-1S


(Oryctolagus
cuniculus)
no annotation 4 LEU A 472
ASN A 468
LEU A 512
ILE A 524
None
0.99A 4ok1A-6byoA:
1.3
4ok1A-6byoA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT D


(Pyrococcus
furiosus)
no annotation 4 LEU H 223
MET H 328
LEU H 324
ILE H 257
None
1.05A 4ok1A-6cfwH:
undetectable
4ok1A-6cfwH:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfz ASK1
DAD2
HSK3


(Chaetomium
thermophilum)
no annotation 4 ASN C  41
LEU G  31
HIS G  30
ILE A  32
None
0.98A 4ok1A-6cfzC:
undetectable
4ok1A-6cfzC:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cia ALDO/KETO REDUCTASE

(Klebsiella
pneumoniae)
no annotation 4 LEU A 144
ASN A 164
MET A 109
ILE A 240
None
None
None
NDP  A 301 (-4.7A)
1.00A 4ok1A-6ciaA:
undetectable
4ok1A-6ciaA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8l -

(-)
no annotation 4 LEU G 439
ASN G 437
LEU G 412
ILE G 467
None
1.01A 4ok1A-6f8lG:
undetectable
4ok1A-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fek PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET


(Homo sapiens)
no annotation 4 LEU A 816
MET A 984
MET A 980
ILE A 890
None
0.84A 4ok1A-6fekA:
undetectable
4ok1A-6fekA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fj4 ENDO-1,4-BETA-XYLANA
SE Y


(Ruminiclostridium
thermocellum)
no annotation 4 ASN A 966
MET A 863
LEU A 958
ILE A 994
None
1.06A 4ok1A-6fj4A:
undetectable
4ok1A-6fj4A:
16.82