SIMILAR PATTERNS OF AMINO ACIDS FOR 4OAD_A_CLMA206_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f2e | GLUTATHIONES-TRANSFERASE (Sphingomonaspaucimobilis) |
PF00043(GST_C)PF02798(GST_N) | 4 | ALA A 190ALA A 193ALA A 194ALA A 197 | None | 0.09A | 4oadA-1f2eA:0.0 | 4oadA-1f2eA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ixl | HYPOTHETICAL PROTEINPH1136 (Pyrococcushorikoshii) |
PF03061(4HBT) | 4 | ALA A 55ALA A 58ALA A 59ALA A 62 | ALA A 55 ( 0.0A)ALA A 58 ( 0.0A)ALA A 59 ( 0.0A)ALA A 62 ( 0.0A) | 0.12A | 4oadA-1ixlA:0.0 | 4oadA-1ixlA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lgh | LIGHT HARVESTINGCOMPLEX II (Phaeospirillummolischianum) |
PF00556(LHC) | 4 | ALA A 32ALA A 35ALA A 36ALA A 39 | LYC A 97 ( 3.6A)HTO A 62 (-3.9A)LYC A 97 ( 3.0A)DET A 75 ( 3.7A) | 0.11A | 4oadA-1lghA:undetectable | 4oadA-1lghA:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lli | PROTEIN (LAMBDAREPRESSOR) (Escherichiavirus Lambda) |
PF01381(HTH_3) | 4 | ALA A 59ALA A 62ALA A 63ALA A 66 | None | 0.12A | 4oadA-1lliA:0.0 | 4oadA-1lliA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m5h | FORMYLMETHANOFURAN--TETRAHYDROMETHANOPTERINFORMYLTRANSFERASE (Archaeoglobusfulgidus) |
PF01913(FTR)PF02741(FTR_C) | 4 | ALA A 179ALA A 182ALA A 183ALA A 186 | None | 0.14A | 4oadA-1m5hA:0.5 | 4oadA-1m5hA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m5s | FORMYLMETHANOFURAN--TETRAHYDROMETHANOPTERINFORMYLTRANSFERASE (Methanosarcinabarkeri) |
PF01913(FTR)PF02741(FTR_C) | 4 | ALA A 176ALA A 179ALA A 180ALA A 183 | None | 0.13A | 4oadA-1m5sA:0.6 | 4oadA-1m5sA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ppr | PERIDININ-CHLOROPHYLL PROTEIN (Amphidiniumcarterae) |
PF02429(PCP) | 4 | ALA M 221ALA M 224ALA M 225ALA M 228 | NoneNoneCLA M 602 (-3.5A)None | 0.09A | 4oadA-1pprM:0.0 | 4oadA-1pprM:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1psq | PROBABLE THIOLPEROXIDASE (Streptococcuspneumoniae) |
PF08534(Redoxin) | 4 | ALA A 155ALA A 158ALA A 159ALA A 162 | None | 0.12A | 4oadA-1psqA:0.0 | 4oadA-1psqA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uc4 | DIOL DEHYDRASE ALPHASUBUNIT (Klebsiellaoxytoca) |
PF02286(Dehydratase_LU) | 4 | ALA A 155ALA A 158ALA A 159ALA A 162 | None | 0.12A | 4oadA-1uc4A:0.0 | 4oadA-1uc4A:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wfa | ANTIFREEZE PROTEINISOFORM HPLC6 (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 3ALA A 6ALA A 7ALA A 10 | None | 0.12A | 4oadA-1wfaA:undetectable | 4oadA-1wfaA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wfa | ANTIFREEZE PROTEINISOFORM HPLC6 (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 7ALA A 10ALA A 11ALA A 14 | None | 0.12A | 4oadA-1wfaA:undetectable | 4oadA-1wfaA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afb | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermotogamaritima) |
PF00294(PfkB) | 4 | ALA A 36ALA A 39ALA A 40ALA A 43 | None | 0.13A | 4oadA-2afbA:0.2 | 4oadA-2afbA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bp1 | AFLATOXIN B1ALDEHYDE REDUCTASEMEMBER 2 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | ALA A 56ALA A 59ALA A 60ALA A 63 | None | 0.06A | 4oadA-2bp1A:undetectable | 4oadA-2bp1A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eba | PUTATIVEGLUTARYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | ALA A 329ALA A 332ALA A 333ALA A 336 | None | 0.13A | 4oadA-2ebaA:undetectable | 4oadA-2ebaA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2es4 | LIPASE CHAPERONE (Burkholderiaglumae) |
PF03280(Lipase_chap) | 4 | ALA D 225ALA D 228ALA D 229ALA D 232 | None | 0.13A | 4oadA-2es4D:undetectable | 4oadA-2es4D:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2his | CELLULOMONAS FIMIFAMILY 10BETA-1,4-GLYCANASE (Cellulomonasfimi) |
PF00331(Glyco_hydro_10) | 4 | ALA A 153ALA A 156ALA A 157ALA A 160 | None | 0.12A | 4oadA-2hisA:undetectable | 4oadA-2hisA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hoe | N-ACETYLGLUCOSAMINEKINASE (Thermotogamaritima) |
PF00480(ROK) | 4 | ALA A 350ALA A 353ALA A 354ALA A 357 | None | 0.10A | 4oadA-2hoeA:undetectable | 4oadA-2hoeA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuy | GLYCOSYLTRANSFERASE (Streptomycesviridochromogenes) |
PF00534(Glycos_transf_1) | 4 | ALA A 187ALA A 190ALA A 191ALA A 194 | None | 0.11A | 4oadA-2iuyA:undetectable | 4oadA-2iuyA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ji9 | OXALYL-COADECARBOXYLASE (Oxalobacterformigenes) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ALA A 59ALA A 62ALA A 63ALA A 66 | None | 0.11A | 4oadA-2ji9A:undetectable | 4oadA-2ji9A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l3w | PHYCOBILISOME RODLINKER POLYPEPTIDE (Synechococcuselongatus) |
PF00427(PBS_linker_poly) | 4 | ALA A 94ALA A 97ALA A 98ALA A 101 | None | 0.13A | 4oadA-2l3wA:undetectable | 4oadA-2l3wA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oej | 2,3-DIKETO-5-METHYLTHIOPENTYL-1-PHOSPHATE ENOLASE (Geobacilluskaustophilus) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | ALA A 375ALA A 378ALA A 379ALA A 382 | None | 0.12A | 4oadA-2oejA:undetectable | 4oadA-2oejA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pif | UPF0317 PROTEINPSPTO_5379 (Pseudomonassyringae groupgenomosp. 3) |
PF07286(DUF1445) | 4 | ALA A 11ALA A 14ALA A 15ALA A 18 | None | 0.13A | 4oadA-2pifA:undetectable | 4oadA-2pifA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r4j | AEROBICGLYCEROL-3-PHOSPHATEDEHYDROGENASE (Escherichiacoli) |
PF01266(DAO)PF16901(DAO_C) | 4 | ALA A 16ALA A 19ALA A 20ALA A 23 | None | 0.13A | 4oadA-2r4jA:undetectable | 4oadA-2r4jA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rkb | SERINEDEHYDRATASE-LIKE (Homo sapiens) |
PF00291(PALP) | 4 | ALA A 75ALA A 78ALA A 79ALA A 82 | None | 0.13A | 4oadA-2rkbA:undetectable | 4oadA-2rkbA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbp | L-ARGININEBETA-HYDROXYLASE (Streptomycesvinaceus) |
PF02668(TauD) | 4 | ALA A 32ALA A 35ALA A 36ALA A 39 | None | 0.10A | 4oadA-2wbpA:undetectable | 4oadA-2wbpA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zsj | THREONINE SYNTHASE (Aquifexaeolicus) |
PF00291(PALP) | 4 | ALA A 92ALA A 95ALA A 96ALA A 99 | None | 0.10A | 4oadA-2zsjA:undetectable | 4oadA-2zsjA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b4w | ALDEHYDEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00171(Aldedh) | 4 | ALA A 50ALA A 53ALA A 54ALA A 57 | None | 0.13A | 4oadA-3b4wA:undetectable | 4oadA-3b4wA:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8b | CYSQ, SULFITESYNTHESIS PATHWAYPROTEIN (Bacteroidesthetaiotaomicron) |
PF00459(Inositol_P) | 4 | ALA A 3ALA A 6ALA A 7ALA A 10 | None | 0.10A | 4oadA-3b8bA:undetectable | 4oadA-3b8bA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cay | LPD-12 (-) |
no annotation | 4 | ALA A 10ALA A 13ALA A 14ALA A 17 | NoneO12 A 24 ( 3.6A)LMT A 512 ( 3.7A)O12 A 24 ( 3.9A) | 0.12A | 4oadA-3cayA:undetectable | 4oadA-3cayA:10.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dr0 | CYTOCHROME C6 (Synechococcussp. PCC 7002) |
PF13442(Cytochrome_CBB3) | 4 | ALA A 78ALA A 81ALA A 82ALA A 85 | None | 0.07A | 4oadA-3dr0A:undetectable | 4oadA-3dr0A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejw | SMLSRB (Sinorhizobiummeliloti) |
PF13407(Peripla_BP_4) | 4 | ALA A 198ALA A 201ALA A 202ALA A 205 | None | 0.10A | 4oadA-3ejwA:undetectable | 4oadA-3ejwA:17.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3go7 | RIBOKINASE RBSK (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 4 | ALA A 152ALA A 155ALA A 156ALA A 159 | None | 0.09A | 4oadA-3go7A:undetectable | 4oadA-3go7A:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htv | D-ALLOSE KINASE (Escherichiacoli) |
PF00480(ROK) | 4 | ALA A 289ALA A 292ALA A 293ALA A 296 | None | 0.13A | 4oadA-3htvA:undetectable | 4oadA-3htvA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ja6 | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN 2 (Escherichiacoli) |
PF00015(MCPsignal) | 4 | ALA H 294ALA H 297ALA H 298ALA H 301 | None | 0.13A | 4oadA-3ja6H:undetectable | 4oadA-3ja6H:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3js8 | CHOLESTEROL OXIDASE (Chromobacteriumsp. DS-1) |
PF01565(FAD_binding_4)PF09129(Chol_subst-bind) | 4 | ALA A 516ALA A 519ALA A 520ALA A 523 | None | 0.13A | 4oadA-3js8A:undetectable | 4oadA-3js8A:14.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kkw | PUTATIVEUNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | ALA A 40ALA A 43ALA A 44ALA A 47 | None | 0.08A | 4oadA-3kkwA:31.9 | 4oadA-3kkwA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwg | HP0420 HOMOLOGUE (Helicobacterfelis) |
no annotation | 4 | ALA A 60ALA A 63ALA A 64ALA A 67 | None | 0.11A | 4oadA-3lwgA:undetectable | 4oadA-3lwgA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mso | STEROIDDELTA-ISOMERASE (Pseudomonasaeruginosa) |
PF12680(SnoaL_2) | 4 | ALA A 8ALA A 11ALA A 12ALA A 15 | None | 0.11A | 4oadA-3msoA:undetectable | 4oadA-3msoA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rnr | STAGE II SPORULATIONE FAMILY PROTEIN (Thermanaerovibrioacidaminovorans) |
PF07228(SpoIIE) | 4 | ALA A 46ALA A 49ALA A 50ALA A 53 | None | 0.10A | 4oadA-3rnrA:undetectable | 4oadA-3rnrA:23.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ta6 | TRIOSEPHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00121(TIM) | 4 | ALA A 249ALA A 252ALA A 253ALA A 256 | None | 0.13A | 4oadA-3ta6A:undetectable | 4oadA-3ta6A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u27 | MICROCOMPARTMENTSPROTEIN (Leptotrichiabuccalis) |
no annotation | 4 | ALA C 195ALA C 198ALA C 199ALA C 202 | None | 0.11A | 4oadA-3u27C:undetectable | 4oadA-3u27C:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9r | METHYLCROTONYL-COACARBOXYLASE,BETA-SUBUNIT (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans) | 4 | ALA B 40ALA B 43ALA B 44ALA B 47 | None | 0.10A | 4oadA-3u9rB:2.0 | 4oadA-3u9rB:15.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ucf | DEHYDROGENASE (Vibriovulnificus) |
PF13561(adh_short_C2) | 4 | ALA A 132ALA A 135ALA A 136ALA A 139 | None | 0.13A | 4oadA-3ucfA:undetectable | 4oadA-3ucfA:24.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5n | PUTATIVERHAMNOSIDASE (Streptomycesavermitilis) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 4 | ALA A 768ALA A 771ALA A 772ALA A 775 | NoneNoneMPD A1209 (-2.9A)None | 0.10A | 4oadA-3w5nA:undetectable | 4oadA-3w5nA:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x0y | DSZC (Rhodococcuserythropolis) |
PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N)PF08028(Acyl-CoA_dh_2) | 4 | ALA A 312ALA A 315ALA A 316ALA A 319 | None | 0.12A | 4oadA-3x0yA:undetectable | 4oadA-3x0yA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x17 | ENDOGLUCANASE (unculturedbacterium) |
no annotation | 4 | ALA B 318ALA B 321ALA B 322ALA B 325 | None | 0.12A | 4oadA-3x17B:undetectable | 4oadA-3x17B:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4auk | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE M (Escherichiacoli) |
PF01728(FtsJ) | 4 | ALA A 283ALA A 286ALA A 287ALA A 290 | EDO A1375 (-3.1A)NoneNoneNone | 0.09A | 4oadA-4aukA:undetectable | 4oadA-4aukA:17.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dq7 | MEMBRANE PROTEINPHI6 P5 (Pseudomonasvirus phi6) |
PF10464(Peptidase_U40) | 4 | ALA A 202ALA A 205ALA A 206ALA A 209 | None | 0.12A | 4oadA-4dq7A:undetectable | 4oadA-4dq7A:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g6b | CITRATE SYNTHASE (Escherichiacoli) |
PF00285(Citrate_synt) | 4 | ALA A 250ALA A 253ALA A 254ALA A 257 | None | 0.09A | 4oadA-4g6bA:undetectable | 4oadA-4g6bA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gci | GLUTATHIONES-TRANSFERASE (Yersinia pestis) |
PF00043(GST_C)PF02798(GST_N) | 4 | ALA A 191ALA A 194ALA A 195ALA A 198 | None | 0.09A | 4oadA-4gciA:undetectable | 4oadA-4gciA:25.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gni | PUTATIVE HEAT SHOCKPROTEIN (Chaetomiumthermophilum) |
PF00012(HSP70) | 4 | ALA A 391ALA A 394ALA A 395ALA A 398 | None | 0.09A | 4oadA-4gniA:undetectable | 4oadA-4gniA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs5 | ACYL-COA SYNTHETASE(AMP-FORMING)/AMP-ACID LIGASE II-LIKEPROTEIN (Dyadobacterfermentans) |
PF00501(AMP-binding) | 4 | ALA A 57ALA A 60ALA A 61ALA A 64 | NoneNoneNoneEDO A 423 (-4.1A) | 0.11A | 4oadA-4gs5A:undetectable | 4oadA-4gs5A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hut | COB(I)YRINIC ACIDA,C-DIAMIDEADENOSYLTRANSFERASE (Salmonellaenterica) |
PF02572(CobA_CobO_BtuR) | 4 | ALA A 100ALA A 103ALA A 104ALA A 107 | None | 0.11A | 4oadA-4hutA:undetectable | 4oadA-4hutA:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i5u | CHIMERIC CEL6A (Humicolainsolens;Trichodermareesei;Chaetomiumthermophilum) |
PF01341(Glyco_hydro_6) | 4 | ALA A 120ALA A 123ALA A 124ALA A 127 | None | 0.13A | 4oadA-4i5uA:undetectable | 4oadA-4i5uA:19.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i7u | DIHYDRODIPICOLINATESYNTHASE (Agrobacteriumsp. H13-3) |
PF00701(DHDPS) | 4 | ALA A 278ALA A 281ALA A 282ALA A 285 | None | 0.12A | 4oadA-4i7uA:undetectable | 4oadA-4i7uA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i8p | AMINOALDEHYDEDEHYDROGENASE 1 (Zea mays) |
PF00171(Aldedh) | 4 | ALA A 51ALA A 54ALA A 55ALA A 58 | None | 0.09A | 4oadA-4i8pA:undetectable | 4oadA-4i8pA:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ig7 | UBIQUITIN C-TERMINALHYDROLASE 37 (Trichinellaspiralis) |
PF01088(Peptidase_C12) | 4 | ALA A 250ALA A 253ALA A 254ALA A 257 | None | 0.08A | 4oadA-4ig7A:undetectable | 4oadA-4ig7A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwv | SHORT CHAINENOYL-COA HYDRATASE (Novosphingobiumaromaticivorans) |
PF00378(ECH_1) | 4 | ALA A 203ALA A 206ALA A 207ALA A 210 | None | 0.12A | 4oadA-4jwvA:undetectable | 4oadA-4jwvA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke2 | TYPE I HYPERACTIVEANTIFREEZE PROTEIN (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 18ALA A 21ALA A 22ALA A 25 | None | 0.13A | 4oadA-4ke2A:undetectable | 4oadA-4ke2A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke2 | TYPE I HYPERACTIVEANTIFREEZE PROTEIN (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 65ALA A 68ALA A 69ALA A 72 | None | 0.10A | 4oadA-4ke2A:undetectable | 4oadA-4ke2A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke2 | TYPE I HYPERACTIVEANTIFREEZE PROTEIN (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 138ALA A 141ALA A 142ALA A 145 | None | 0.11A | 4oadA-4ke2A:undetectable | 4oadA-4ke2A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke2 | TYPE I HYPERACTIVEANTIFREEZE PROTEIN (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 152ALA A 155ALA A 156ALA A 159 | None | 0.12A | 4oadA-4ke2A:undetectable | 4oadA-4ke2A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke2 | TYPE I HYPERACTIVEANTIFREEZE PROTEIN (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 156ALA A 159ALA A 160ALA A 163 | None | 0.12A | 4oadA-4ke2A:undetectable | 4oadA-4ke2A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ke2 | TYPE I HYPERACTIVEANTIFREEZE PROTEIN (Pseudopleuronectesamericanus) |
no annotation | 4 | ALA A 170ALA A 173ALA A 174ALA A 177 | None | 0.13A | 4oadA-4ke2A:undetectable | 4oadA-4ke2A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mrp | ABC TRANSPORTERRELATED PROTEIN (Novosphingobiumaromaticivorans) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 4 | ALA A 594ALA A 597ALA A 598ALA A 601 | None | 0.10A | 4oadA-4mrpA:undetectable | 4oadA-4mrpA:14.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nbv | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE PUTATIVESHORT-CHAINDEHYDROGENASES/REDUCTASES (SDR) FAMILYPROTEIN (Cupriavidustaiwanensis) |
PF13561(adh_short_C2) | 4 | ALA A 71ALA A 74ALA A 75ALA A 78 | None | 0.12A | 4oadA-4nbvA:undetectable | 4oadA-4nbvA:26.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nyn | RIBONUCLEASE HI (Halobacteriumsalinarum) |
PF13456(RVT_3) | 4 | ALA A 118ALA A 121ALA A 122ALA A 125 | None | 0.12A | 4oadA-4nynA:undetectable | 4oadA-4nynA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqy | (S)-IMINE REDUCTASE (Streptomycessp. GF3546) |
PF03446(NAD_binding_2) | 4 | ALA A 100ALA A 103ALA A 104ALA A 107 | None | 0.11A | 4oadA-4oqyA:undetectable | 4oadA-4oqyA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q16 | NH(3)-DEPENDENTNAD(+) SYNTHETASE (Deinococcusradiodurans) |
PF02540(NAD_synthase) | 4 | ALA A 122ALA A 125ALA A 126ALA A 129 | None | 0.10A | 4oadA-4q16A:undetectable | 4oadA-4q16A:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rdy | PARATHION HYDROLASE (Vulcanisaetamoutnovskia) |
PF02126(PTE) | 4 | ALA A 153ALA A 156ALA A 157ALA A 160 | NoneNoneKCX A 138 ( 3.7A)None | 0.13A | 4oadA-4rdyA:undetectable | 4oadA-4rdyA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3w | 2-AMINOMUCONATE6-SEMIALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 4 | ALA A 55ALA A 58ALA A 59ALA A 62 | None | 0.12A | 4oadA-4u3wA:undetectable | 4oadA-4u3wA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4url | DNA TOPOISOMERASEIV, B SUBUNIT (Staphylococcusaureus) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | ALA A 387ALA A 390ALA A 391ALA A 394 | None | 0.11A | 4oadA-4urlA:undetectable | 4oadA-4urlA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb6 | ALPHA-D-RIBOSE1-METHYLPHOSPHONATE5-TRIPHOSPHATESYNTHASE SUBUNITPHNG (Escherichiacoli) |
PF06754(PhnG) | 4 | ALA A 125ALA A 128ALA A 129ALA A 132 | None | 0.13A | 4oadA-4xb6A:undetectable | 4oadA-4xb6A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztx | COBALAMIN-INDEPENDENT METHIONINESYNTHASE (Neurosporacrassa) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | ALA A 383ALA A 386ALA A 387ALA A 390 | None | 0.10A | 4oadA-4ztxA:undetectable | 4oadA-4ztxA:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp8 | ENT-COPALYLDIPHOSPHATE SYNTHASE (Streptomycesplatensis) |
PF00432(Prenyltrans)PF13243(SQHop_cyclase_C) | 4 | ALA A 15ALA A 18ALA A 19ALA A 22 | None | 0.13A | 4oadA-5bp8A:undetectable | 4oadA-5bp8A:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwi | DESIGNED HELICALREPEAT PROTEIN (syntheticconstruct) |
no annotation | 4 | ALA A 74ALA A 77ALA A 78ALA A 81 | None | 0.08A | 4oadA-5cwiA:undetectable | 4oadA-5cwiA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwi | DESIGNED HELICALREPEAT PROTEIN (syntheticconstruct) |
no annotation | 4 | ALA A 134ALA A 137ALA A 138ALA A 141 | None | 0.11A | 4oadA-5cwiA:undetectable | 4oadA-5cwiA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwi | DESIGNED HELICALREPEAT PROTEIN (syntheticconstruct) |
no annotation | 4 | ALA A 198ALA A 201ALA A 202ALA A 205 | None | 0.11A | 4oadA-5cwiA:undetectable | 4oadA-5cwiA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6v | CARBOXYSOME SHELLPROTEIN (Salmonellaenterica) |
PF00936(BMC) | 4 | ALA A 52ALA A 55ALA A 56ALA A 59 | None | 0.13A | 4oadA-5d6vA:undetectable | 4oadA-5d6vA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iuy | MULTIDRUG EFFLUXOUTER MEMBRANEPROTEIN OPRN (Pseudomonasaeruginosa) |
PF02321(OEP) | 4 | ALA A 203ALA A 206ALA A 207ALA A 210 | None | 0.13A | 4oadA-5iuyA:undetectable | 4oadA-5iuyA:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j6b | ALDEHYDEDEHYDROGENASE (Burkholderiathailandensis) |
PF00171(Aldedh) | 4 | ALA A 42ALA A 45ALA A 46ALA A 49 | None | 0.11A | 4oadA-5j6bA:undetectable | 4oadA-5j6bA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jry | NAD-DEPENDENTALDEHYDEDEHYDROGENASE (Burkholderiamultivorans) |
PF00171(Aldedh) | 4 | ALA A 42ALA A 45ALA A 46ALA A 49 | None | 0.10A | 4oadA-5jryA:undetectable | 4oadA-5jryA:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ju9 | BETA-1,4-MANNANASE (Streptomycessp. NRRLB-24361) |
no annotation | 4 | ALA A 137ALA A 140ALA A 141ALA A 144 | None | 0.13A | 4oadA-5ju9A:undetectable | 4oadA-5ju9A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l39 | RMM MICROCOMPARTMENTSHELL PROTEINMSM0275 (Mycolicibacteriumsmegmatis) |
PF00936(BMC) | 4 | ALA A 188ALA A 191ALA A 192ALA A 195 | None | 0.13A | 4oadA-5l39A:undetectable | 4oadA-5l39A:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdx | PHOTOSYSTEM IIPROTEIN D1 (Arabidopsisthaliana) |
PF00124(Photo_RC) | 4 | ALA A 149ALA A 152ALA A 153ALA A 156 | PHO A 404 ( 3.8A)NoneCLA A 402 ( 3.7A)None | 0.00A | 4oadA-5mdxA:undetectable | 4oadA-5mdxA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5suh | MSM0271 PROTEIN (Mycolicibacteriumsmegmatis) |
no annotation | 4 | ALA A 162ALA A 165ALA A 166ALA A 169 | None | 0.13A | 4oadA-5suhA:undetectable | 4oadA-5suhA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5umf | RIBULOSE-PHOSPHATE3-EPIMERASE (Neisseriagonorrhoeae) |
PF00834(Ribul_P_3_epim) | 4 | ALA A 213ALA A 216ALA A 217ALA A 220 | None | 0.13A | 4oadA-5umfA:undetectable | 4oadA-5umfA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5va8 | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Paraburkholderiaphymatum) |
PF13561(adh_short_C2) | 4 | ALA A 46ALA A 49ALA A 50ALA A 53 | None | 0.12A | 4oadA-5va8A:undetectable | 4oadA-5va8A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vbf | NAD-DEPENDENTSUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Burkholderiavietnamiensis) |
PF00171(Aldedh) | 4 | ALA A 54ALA A 57ALA A 58ALA A 61 | None | 0.09A | 4oadA-5vbfA:undetectable | 4oadA-5vbfA:17.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vdb | ACETYLTRANSFERASEPA4794 (Pseudomonasaeruginosa) |
PF00583(Acetyltransf_1) | 4 | ALA A 40ALA A 43ALA A 44ALA A 47 | None | 0.06A | 4oadA-5vdbA:31.8 | 4oadA-5vdbA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vtl | - (-) |
no annotation | 4 | ALA A 212ALA A 215ALA A 216ALA A 219 | None | 0.13A | 4oadA-5vtlA:undetectable | 4oadA-5vtlA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8o | HOMOSERINEO-ACETYLTRANSFERASE (Mycolicibacteriumhassiacum) |
PF00561(Abhydrolase_1) | 4 | ALA A 137ALA A 140ALA A 141ALA A 144 | None | 0.12A | 4oadA-5w8oA:undetectable | 4oadA-5w8oA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x7n | DIAMINOPIMELATEDECARBOXYLASE (Corynebacteriumglutamicum) |
no annotation | 4 | ALA A 195ALA A 198ALA A 199ALA A 202 | None | 0.11A | 4oadA-5x7nA:undetectable | 4oadA-5x7nA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xd6 | PROTEIN KINASESUPERFAMILY PROTEIN (Arabidopsisthaliana) |
no annotation | 4 | ALA A 318ALA A 321ALA A 322ALA A 325 | None | 0.10A | 4oadA-5xd6A:undetectable | 4oadA-5xd6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xev | XAA-PRODIPEPTIDASE,PEPTIDASE-RELATED PROTEIN (Deinococcusradiodurans) |
no annotation | 4 | ALA A 272ALA A 275ALA A 276ALA A 279 | None | 0.13A | 4oadA-5xevA:undetectable | 4oadA-5xevA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xzu | BETA-XYLANASE (Bispora sp.MEY-1) |
no annotation | 4 | ALA A 272ALA A 275ALA A 276ALA A 279 | None | 0.12A | 4oadA-5xzuA:undetectable | 4oadA-5xzuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yap | SCYLLO-INOSITOLDEHYDROGENASE WITHL-GLUCOSEDEHYDROGENASEACTIVITY (Paracoccuslaeviglucosivorans) |
no annotation | 4 | ALA A 117ALA A 120ALA A 121ALA A 124 | None | 0.13A | 4oadA-5yapA:undetectable | 4oadA-5yapA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9y | THIAZOLE SYNTHASE (Mycobacteriumtuberculosis) |
no annotation | 4 | ALA A 218ALA A 221ALA A 222ALA A 225 | None | 0.12A | 4oadA-5z9yA:undetectable | 4oadA-5z9yA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b4m | MONOTREME LACTATIONPROTEIN (Ornithorhynchusanatinus) |
no annotation | 4 | ALA A 140ALA A 143ALA A 144ALA A 147 | None | 0.10A | 4oadA-6b4mA:undetectable | 4oadA-6b4mA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cao | - (-) |
no annotation | 4 | ALA K 65ALA K 68ALA K 69ALA K 72 | None | 0.12A | 4oadA-6caoK:undetectable | 4oadA-6caoK:21.64 |