SIMILAR PATTERNS OF AMINO ACIDS FOR 4O2B_B_LOCB503_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1al8 | GLYCOLATE OXIDASE (Spinaciaoleracea) |
PF01070(FMN_dh) | 5 | LEU A 298ALA A 297MET A 74THR A 101ILE A 64 | None | 1.08A | 4o2bB-1al8A:2.7 | 4o2bB-1al8A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bud | PROTEIN (ACUTOLYSINA) (Deinagkistrodonacutus) |
PF01421(Reprolysin) | 5 | LEU A 47LEU A 148ASN A 147MET A 116ILE A 198 | None | 1.05A | 4o2bB-1budA:undetectable | 4o2bB-1budA:16.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2r | PROTEIN(TRYPTOPHANYL TRNASYNTHETASE) (Geobacillusstearothermophilus) |
PF00579(tRNA-synt_1b) | 5 | LEU A 272ALA A 220MET A 193ILE A 213ILE A 16 | None | 1.07A | 4o2bB-1d2rA:undetectable | 4o2bB-1d2rA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ej6 | LAMBDA1 (Reovirus sp.) |
no annotation | 5 | LEU B 595ALA B 815LEU B 549ALA B 885ILE B 551 | None | 1.07A | 4o2bB-1ej6B:undetectable | 4o2bB-1ej6B:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g61 | TRANSLATIONINITIATION FACTOR 6 (Methanocaldococcusjannaschii) |
PF01912(eIF-6) | 5 | LEU A2020LEU A2107LEU A2070ILE A2053ILE A2084 | None | 0.96A | 4o2bB-1g61A:undetectable | 4o2bB-1g61A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gud | D-ALLOSE-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF13407(Peripla_BP_4) | 5 | LEU A 188ASN A 191ALA A 137ILE A 139ILE A 197 | None | 1.10A | 4o2bB-1gudA:4.1 | 4o2bB-1gudA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h6u | INTERNALIN H (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4)PF13516(LRR_6) | 5 | LEU A 103ALA A 83LEU A 53ILE A 78LYS A 58 | None | 1.00A | 4o2bB-1h6uA:undetectable | 4o2bB-1h6uA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1htd | ATROLYSIN C (Crotalus atrox) |
PF01421(Reprolysin) | 5 | LEU A 47LEU A 148ASN A 147MET A 116ILE A 198 | None | 1.07A | 4o2bB-1htdA:undetectable | 4o2bB-1htdA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i6a | HYDROGENPEROXIDE-INDUCIBLEGENES ACTIVATOR (Escherichiacoli) |
PF03466(LysR_substrate) | 6 | LEU A 93LEU A 124LEU A 113MET A 112ILE A 145ILE A 289 | None | 1.49A | 4o2bB-1i6aA:undetectable | 4o2bB-1i6aA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i8a | ENDO-1,4-BETA-XYLANASE A (Thermotogamaritima) |
PF06452(CBM9_1) | 5 | LEU A 52LEU A 184ASN A 183ILE A 150ILE A 25 | None | 0.99A | 4o2bB-1i8aA:undetectable | 4o2bB-1i8aA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1izo | CYTOCHROME P450152A1 (Bacillussubtilis) |
PF00067(p450) | 5 | LEU A 241LEU A 102LEU A 214ALA A 218ILE A 198 | None | 1.05A | 4o2bB-1izoA:undetectable | 4o2bB-1izoA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ko0 | DIAMINOPIMELATEDECARBOXYLASE (Escherichiacoli) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | LEU A 175LEU A 127LEU A 185ILE A 166ILE A 188 | None | 1.11A | 4o2bB-1ko0A:undetectable | 4o2bB-1ko0A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8w | VLSE1 (Borreliellaburgdorferi) |
PF00921(Lipoprotein_2) | 5 | LEU A 286ALA A 259ASN A 254ALA A 234ILE A 231 | None | 0.83A | 4o2bB-1l8wA:undetectable | 4o2bB-1l8wA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lvl | DIHYDROLIPOAMIDEDEHYDROGENASE (Pseudomonasputida) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | LEU A 8LEU A 33ALA A 21ALA A 141ILE A 11 | NoneNoneNoneFAD A 459 (-4.5A)FAD A 459 (-4.5A) | 1.10A | 4o2bB-1lvlA:undetectable | 4o2bB-1lvlA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mus | TN5 TRANSPOSASE (Escherichiacoli) |
PF01609(DDE_Tnp_1)PF02281(Dimer_Tnp_Tn5)PF14706(Tnp_DNA_bind) | 5 | LEU A 356LEU A 38ALA A 60ILE A 64ILE A 46 | None | 1.12A | 4o2bB-1musA:undetectable | 4o2bB-1musA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pz3 | ALPHA-L-ARABINOFURANOSIDASE (Geobacillusstearothermophilus) |
PF06964(Alpha-L-AF_C) | 5 | CYH A 438LEU A 408ASN A 427ALA A 425ILE A 423 | None | 1.12A | 4o2bB-1pz3A:undetectable | 4o2bB-1pz3A:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q0u | BSTDEAD (Geobacillusstearothermophilus) |
PF00270(DEAD) | 5 | LEU A 185ALA A 38ALA A 75ILE A 77ILE A 129 | None | 1.02A | 4o2bB-1q0uA:undetectable | 4o2bB-1q0uA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1soj | CGMP-INHIBITED3',5'-CYCLICPHOSPHODIESTERASE B (Homo sapiens) |
PF00233(PDEase_I) | 5 | CYH A 929LEU A 926ALA A 889LEU A 885ILE A 806 | None | 1.12A | 4o2bB-1sojA:undetectable | 4o2bB-1sojA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w99 | PESTICIDIAL CRYSTALPROTEIN CRY4BA (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | LEU A 517LEU A 511ALA A 495THR A 609ALA A 611 | None | 0.90A | 4o2bB-1w99A:undetectable | 4o2bB-1w99A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b7n | PROBABLENICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Helicobacterpylori) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | LEU A 168ASN A 200ALA A 203ILE A 185ILE A 187 | None | 1.01A | 4o2bB-2b7nA:undetectable | 4o2bB-2b7nA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buc | DIPEPTIDYL PEPTIDASEIV (Sus scrofa) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | LEU A 410LEU A 436ASN A 437LYS A 441ILE A 397 | None | 1.11A | 4o2bB-2bucA:undetectable | 4o2bB-2bucA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ec5 | DERMONECROTIC TOXIN (Pasteurellamultocida) |
PF11647(MLD) | 5 | LEU A1176MET A1179ILE A1235LYS A1153ILE A1148 | None | 1.10A | 4o2bB-2ec5A:undetectable | 4o2bB-2ec5A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g4o | 3-ISOPROPYLMALATEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00180(Iso_dh) | 5 | LEU A 49ASN A 59ALA A 4ILE A 6ILE A 63 | None | 0.96A | 4o2bB-2g4oA:undetectable | 4o2bB-2g4oA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gca | FOLYLPOLYGLUTAMATESYNTHASE (Lactobacilluscasei) |
PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | LEU A 415LEU A 395THR A 337ILE A 312ILE A 310 | None | 1.06A | 4o2bB-2gcaA:3.1 | 4o2bB-2gcaA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2krs | PROBABLE ENTEROTOXIN (Clostridiumperfringens) |
PF08239(SH3_3) | 5 | LEU A 27ASN A 12ALA A 54ILE A 59ILE A 45 | None | 1.03A | 4o2bB-2krsA:undetectable | 4o2bB-2krsA:10.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o1s | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF02779(Transket_pyr)PF02780(Transketolase_C)PF13292(DXP_synthase_N) | 5 | LEU A 242ASN A 165ALA A 160ILE A 155ILE A 127 | None | 1.08A | 4o2bB-2o1sA:undetectable | 4o2bB-2o1sA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oox | HYPOTHETICAL PROTEINC1556.08C INCHROMOSOME I (Schizosaccharomycespombe) |
no annotation | 5 | CYH G 132LEU G 128LEU G 167THR G 177ILE G 314 | None | 1.10A | 4o2bB-2ooxG:undetectable | 4o2bB-2ooxG:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oze | ORF DELTA' (Streptococcuspyogenes) |
PF13614(AAA_31) | 5 | LEU A 40ALA A 173THR A 78ILE A 159LYS A 50 | NoneNoneAGS A 300 ( 4.7A)NoneAGS A 300 (-2.6A) | 1.12A | 4o2bB-2ozeA:undetectable | 4o2bB-2ozeA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3v | INOSITOL-1-MONOPHOSPHATASE (Thermotogamaritima) |
PF00459(Inositol_P) | 5 | LEU A1179ALA A1113ALA A1186ILE A1208ILE A1135 | None | 1.04A | 4o2bB-2p3vA:undetectable | 4o2bB-2p3vA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q42 | PUTATIVEHYDROXYACYLGLUTATHIONE HYDROLASE 2 (Arabidopsisthaliana) |
PF00753(Lactamase_B)PF16123(HAGH_C) | 5 | LEU A 47ALA A 72ASN A 63ALA A 33ILE A 37 | None | 0.98A | 4o2bB-2q42A:undetectable | 4o2bB-2q42A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qs8 | XAA-PRO DIPEPTIDASE (Alteromonasmacleodii) |
PF01979(Amidohydro_1) | 5 | LEU A 16LEU A 56ALA A 385LEU A 383ILE A 32 | None | 1.07A | 4o2bB-2qs8A:2.8 | 4o2bB-2qs8A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5f | TRANSCRIPTIONALREGULATOR, PUTATIVE (Pseudomonassyringae groupgenomosp. 3) |
PF04198(Sugar-bind) | 5 | LEU A 283ALA A 100LEU A 104ILE A 116ILE A 114 | None | 1.00A | 4o2bB-2r5fA:undetectable | 4o2bB-2r5fA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v7b | BENZOATE-COENZYME ALIGASE (Paraburkholderiaxenovorans) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | LEU A 167LEU A 65ALA A 123ILE A 125ILE A 76 | None | 0.88A | 4o2bB-2v7bA:undetectable | 4o2bB-2v7bA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xe4 | OLIGOPEPTIDASE B (Leishmaniamajor) |
PF00326(Peptidase_S9)PF02897(Peptidase_S9_N) | 5 | LEU A 598THR A 724ALA A 715ILE A 712ILE A 79 | PGR A1742 (-4.0A)NoneNoneNoneNone | 1.04A | 4o2bB-2xe4A:2.5 | 4o2bB-2xe4A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp2 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 5 | LEU A 439ALA A 373THR A 40ALA A 317ILE A 437 | NoneNoneNAG A 802 ( 4.0A)NoneNone | 1.06A | 4o2bB-2yp2A:undetectable | 4o2bB-2yp2A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zci | PHOSPHOENOLPYRUVATECARBOXYKINASE [GTP] (Corynebacteriumglutamicum) |
PF00821(PEPCK_C)PF17297(PEPCK_N) | 5 | LEU A 252ALA A 269LEU A 416ALA A 414ILE A 412 | None | 1.07A | 4o2bB-2zciA:2.2 | 4o2bB-2zciA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zs0 | EXTRACELLULAR GIANTHEMOGLOBIN MAJORGLOBIN SUBUNIT B1 (Oligobrachiamashikoi) |
PF00042(Globin) | 5 | LEU D 110ALA D 113ALA D 72ILE D 137ILE D 76 | HEM D 200 (-3.8A)NoneHEM D 200 ( 4.7A)NoneNone | 1.07A | 4o2bB-2zs0D:undetectable | 4o2bB-2zs0D:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aoe | GLUTAMATEDEHYDROGENASE (Thermusthermophilus) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 5 | ALA A 394THR A 205ALA A 209ILE A 213ILE A 319 | None | 1.12A | 4o2bB-3aoeA:undetectable | 4o2bB-3aoeA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3apm | PROTEIN-ARGININEDEIMINASE TYPE-4 (Homo sapiens) |
PF03068(PAD)PF08526(PAD_N)PF08527(PAD_M) | 5 | LEU A 462LEU A 467ASN A 588ALA A 492ILE A 546 | None | 1.12A | 4o2bB-3apmA:undetectable | 4o2bB-3apmA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b43 | TITIN (Oryctolaguscuniculus) |
PF07679(I-set) | 5 | LEU A 375LEU A 293LEU A 345MET A 336ILE A 328 | None | 1.11A | 4o2bB-3b43A:undetectable | 4o2bB-3b43A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b59 | GLYOXALASE/BLEOMYCINRESISTANCEPROTEIN/DIOXYGENASE (Novosphingobiumaromaticivorans) |
PF00903(Glyoxalase) | 5 | ALA A 188LEU A 147ASN A 197ILE A 9ILE A 68 | None | 1.00A | 4o2bB-3b59A:undetectable | 4o2bB-3b59A:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgi | PROPANEDIOLUTILIZATION PROTEINPDUU (Salmonellaenterica) |
PF00936(BMC) | 5 | LEU A 84ALA A 64THR A 110ALA A 23ILE A 113 | None | 1.07A | 4o2bB-3cgiA:undetectable | 4o2bB-3cgiA:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fxi | TOLL-LIKE RECEPTOR 4 (Homo sapiens) |
PF13516(LRR_6)PF13855(LRR_8) | 5 | LEU A 258LEU A 208ASN A 213MET A 215ILE A 218 | None | 0.98A | 4o2bB-3fxiA:undetectable | 4o2bB-3fxiA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g85 | TRANSCRIPTIONALREGULATOR (LACIFAMILY) (Clostridiumacetobutylicum) |
PF13377(Peripla_BP_3) | 5 | CYH A 248LEU A 246ALA A 185ALA A 232ILE A 253 | None | 1.02A | 4o2bB-3g85A:2.8 | 4o2bB-3g85A:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | LEU A 559ALA A 579ASN A 595ILE A 603ILE A 468 | None | 1.01A | 4o2bB-3lk6A:6.4 | 4o2bB-3lk6A:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mjz | FG41 MALONATESEMIALDEHYDEDECARBOXYLASE (coryneformbacterium) |
PF14552(Tautomerase_2) | 5 | ALA A 87LEU A 27THR A 72ILE A 68ILE A 3 | None | 1.12A | 4o2bB-3mjzA:undetectable | 4o2bB-3mjzA:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myr | NICKEL-DEPENDENTHYDROGENASE LARGESUBUNIT (Allochromatiumvinosum) |
PF00374(NiFeSe_Hases) | 5 | LEU B1536ALA B1021ILE B1019LYS B1003ILE B1028 | None | 1.12A | 4o2bB-3myrB:undetectable | 4o2bB-3myrB:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n92 | ALPHA-AMYLASE, GH57FAMILY (Thermococcuskodakarensis) |
PF03065(Glyco_hydro_57)PF09210(DUF1957) | 5 | ALA A 185LEU A 148ALA A 142ILE A 179ILE A 161 | None | 1.05A | 4o2bB-3n92A:undetectable | 4o2bB-3n92A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3out | GLUTAMATE RACEMASE (Francisellatularensis) |
PF01177(Asp_Glu_race) | 5 | LEU A 216ASN A 219ALA A 69ILE A 71ILE A 7 | None | 1.06A | 4o2bB-3outA:undetectable | 4o2bB-3outA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pr2 | TRYPTOPHAN SYNTHASEBETA CHAIN (Salmonellaenterica) |
PF00291(PALP) | 5 | LEU B 271ALA B 284THR B 199ALA B 191ILE B 238 | None | 1.00A | 4o2bB-3pr2B:2.1 | 4o2bB-3pr2B:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pv2 | DEGQ (Legionellafallonii) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | LEU A 115THR A 209ILE A 227LYS A 180ILE A 207 | None | 1.11A | 4o2bB-3pv2A:undetectable | 4o2bB-3pv2A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q3c | PROBABLE3-HYDROXYISOBUTYRATEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 5 | LEU A 40LEU A 20ASN A 19MET A 154ILE A 62 | None | 0.99A | 4o2bB-3q3cA:3.8 | 4o2bB-3q3cA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r5x | D-ALANINE--D-ALANINELIGASE (Bacillusanthracis) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 5 | LEU A 58LEU A 74ALA A 50ILE A 38ILE A 53 | None | 1.06A | 4o2bB-3r5xA:undetectable | 4o2bB-3r5xA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rg1 | CD180 MOLECULE (Bos taurus) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | LEU A 525LEU A 498LEU A 503THR A 459ILE A 486 | None | 1.09A | 4o2bB-3rg1A:undetectable | 4o2bB-3rg1A:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3si9 | DIHYDRODIPICOLINATESYNTHASE (Bartonellahenselae) |
PF00701(DHDPS) | 5 | ALA A 293LEU A 244ALA A 260LYS A 263ILE A 257 | None | 1.01A | 4o2bB-3si9A:3.3 | 4o2bB-3si9A:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sz3 | TRYPTOPHANYL-TRNASYNTHETASE (Vibrio cholerae) |
PF00579(tRNA-synt_1b) | 5 | ALA A 226ASN A 208MET A 199ILE A 219ILE A 18 | None | 1.03A | 4o2bB-3sz3A:undetectable | 4o2bB-3sz3A:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3twk | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1 (Arabidopsisthaliana) |
PF01149(Fapy_DNA_glyco)PF06831(H2TH) | 5 | CYH A 18LEU A 19LEU A 114LEU A 64ILE A 84 | None | 1.10A | 4o2bB-3twkA:undetectable | 4o2bB-3twkA:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2h | D-BETA-HYDROXYBUTYRATE DEHYDROGENASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 5 | LEU A 22MET A 0ALA A 237ILE A 136ILE A 84 | None | 1.00A | 4o2bB-3v2hA:7.2 | 4o2bB-3v2hA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wtc | PUTATIVEOXIDOREDUCTASE (Gluconobacteroxydans) |
PF00106(adh_short) | 5 | LEU A 73THR A 11ALA A 9ILE A 7ILE A 33 | None | 0.98A | 4o2bB-3wtcA:7.1 | 4o2bB-3wtcA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bru | ATP-DEPENDENT RNAHELICASE DHH1 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | LEU A 223ALA A 80ALA A 117ILE A 119ILE A 167 | None | 0.96A | 4o2bB-4bruA:undetectable | 4o2bB-4bruA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3s | ALDEHYDEDEHYDROGENASE (Lachnoclostridiumphytofermentans) |
PF00171(Aldedh) | 5 | ALA A 99THR A 168ALA A 172ILE A 176ILE A 143 | None | 1.11A | 4o2bB-4c3sA:undetectable | 4o2bB-4c3sA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c90 | ALPHA-GLUCURONIDASEGH115 (Bacteroidesovatus) |
PF15979(Glyco_hydro_115) | 5 | LEU A 86THR A 100ALA A 98ILE A 96ILE A 145 | None | 0.92A | 4o2bB-4c90A:undetectable | 4o2bB-4c90A:17.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d5r | A49 (Vaccinia virus) |
PF06489(Orthopox_A49R) | 5 | LEU A 65LEU A 153ASN A 108ILE A 146ILE A 142 | None | 1.00A | 4o2bB-4d5rA:undetectable | 4o2bB-4d5rA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e9o | IMV MEMBRANE PROTEIN (Vaccinia virus) |
PF00194(Carb_anhydrase) | 5 | LEU X 93LEU X 159ASN X 158ILE X 45ILE X 134 | NoneNoneIOD X 301 (-4.6A)NoneNone | 1.11A | 4o2bB-4e9oX:undetectable | 4o2bB-4e9oX:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ezb | UNCHARACTERIZEDCONSERVED PROTEIN (Sinorhizobiummeliloti) |
PF03807(F420_oxidored)PF09130(DUF1932) | 5 | LEU A 56THR A 3ALA A 5ILE A 7ILE A 62 | None | 1.06A | 4o2bB-4ezbA:undetectable | 4o2bB-4ezbA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4krt | AUTOLYTIC LYSOZYME (Clostridiumphage phiSM101) |
PF01183(Glyco_hydro_25)PF08239(SH3_3) | 5 | CYH A 117LEU A 121THR A 138ALA A 141ILE A 169 | None | 1.11A | 4o2bB-4krtA:undetectable | 4o2bB-4krtA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lhq | CAMELID NANOBODY (Vicugna pacos) |
PF07686(V-set) | 5 | CYH B 22LEU B 4ALA B 24ASN B 32ILE B 51 | None | 0.86A | 4o2bB-4lhqB:undetectable | 4o2bB-4lhqB:12.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lix | ENT-COPALYLDIPHOSPHATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | LEU A 125ALA A 121ALA A 221ILE A 224ILE A 226 | None | 1.06A | 4o2bB-4lixA:undetectable | 4o2bB-4lixA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1n | SUPERANTIGEN-LIKEPROTEIN (Staphylococcusaureus) |
PF02876(Stap_Strp_tox_C)PF09199(SSL_OB) | 5 | LEU A 142ASN A 195MET A 166ILE A 133ILE A 189 | None | 1.04A | 4o2bB-4o1nA:undetectable | 4o2bB-4o1nA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p1e | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Escherichiafergusonii) |
PF03480(DctP) | 5 | LEU A 248LEU A 30ASN A 31ILE A 242ILE A 241 | None | 1.11A | 4o2bB-4p1eA:undetectable | 4o2bB-4p1eA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pbv | NT-3 GROWTH FACTORRECEPTOR (Gallus gallus) |
PF00047(ig)PF13855(LRR_8)PF16920(TPKR_C2) | 5 | LEU A 146LEU A 94ASN A 117ILE A 132ILE A 110 | None | 1.09A | 4o2bB-4pbvA:undetectable | 4o2bB-4pbvA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pmh | PECTINESTERASE (Sitophilusoryzae) |
PF01095(Pectinesterase) | 5 | ALA A 130ASN A 60ALA A 54ILE A 51ILE A 69 | None | 1.03A | 4o2bB-4pmhA:undetectable | 4o2bB-4pmhA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6j | LMO0131 PROTEIN (Listeriamonocytogenes) |
PF00563(EAL) | 5 | LEU A 60ALA A 62ASN A 15ALA A 11ILE A 8 | None | 1.05A | 4o2bB-4q6jA:undetectable | 4o2bB-4q6jA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7z | CELL DIVISIONCONTROL PROTEIN 21 (Pyrococcusfuriosus) |
PF00493(MCM) | 5 | LEU A 757ALA A 348LEU A 344ASN A 343ILE A 300 | None | 1.12A | 4o2bB-4r7zA:undetectable | 4o2bB-4r7zA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uj5 | RAB-3A-INTERACTINGPROTEIN (Homo sapiens) |
no annotation | 5 | LEU C 333LEU C 340LEU C 353ILE C 403ILE C 355 | None | 1.00A | 4o2bB-4uj5C:undetectable | 4o2bB-4uj5C:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y61 | SLIT AND NTRK-LIKEPROTEIN 2 (Mus musculus) |
PF13855(LRR_8) | 5 | LEU B 139LEU B 91LEU B 117ASN B 96ILE B 101 | None | 1.10A | 4o2bB-4y61B:undetectable | 4o2bB-4y61B:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a9p | POLYHEDRIN (Operophterabrumatacypovirus 18) |
PF05865(Cypo_polyhedrin) | 5 | LEU A 168LEU A 177MET A 124THR A 146ILE A 111 | None | 1.09A | 4o2bB-5a9pA:undetectable | 4o2bB-5a9pA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d0f | UNCHARACTERIZEDPROTEIN ([Candida]glabrata) |
PF06202(GDE_C)PF14699(hGDE_N)PF14701(hDGE_amylase)PF14702(hGDE_central) | 5 | LEU A 830LEU A 734ALA A 806ILE A 860ILE A 862 | None | 1.07A | 4o2bB-5d0fA:undetectable | 4o2bB-5d0fA:14.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gn1 | ATP-DEPENDENTHELICASE FUN30 (Saccharomycescerevisiae) |
PF00176(SNF2_N)PF00271(Helicase_C) | 5 | LEU A 989LEU A 982THR A1071ILE A1020ILE A 961 | None | 1.12A | 4o2bB-5gn1A:undetectable | 4o2bB-5gn1A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | CYH A 338LEU A 362LEU A 317LEU A 344ILE A 331 | None | 1.04A | 4o2bB-5gr8A:undetectable | 4o2bB-5gr8A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gr8 | LEUCINE-RICH REPEATRECEPTOR-LIKEPROTEIN KINASE PEPR1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | LEU A 239LEU A 221LEU A 226ILE A 191ILE A 187 | None | 1.11A | 4o2bB-5gr8A:undetectable | 4o2bB-5gr8A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hsg | PUTATIVE ABCTRANSPORTER,NUCLEOTIDEBINDING/ATPASEPROTEIN (Klebsiellapneumoniae) |
PF13407(Peripla_BP_4) | 6 | LEU A 93ALA A 118ALA A 109ILE A 81LYS A 107ILE A 114 | None | 1.30A | 4o2bB-5hsgA:3.9 | 4o2bB-5hsgA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jdd | TITIN (Homo sapiens) |
PF07679(I-set) | 5 | LEU A 260LEU A 184LEU A 234MET A 225ILE A 217 | None | 1.01A | 4o2bB-5jddA:undetectable | 4o2bB-5jddA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jkj | ESTERASE E22 (unculturedbacterium) |
PF00561(Abhydrolase_1) | 5 | LEU A 237LEU A 244ALA A 295ASN A 118ILE A 219 | None | 1.08A | 4o2bB-5jkjA:2.9 | 4o2bB-5jkjA:24.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jqe | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN,CASPASE-8CHIMERA (Escherichiacoli) |
PF01335(DED)PF13416(SBP_bac_8) | 5 | LEU A 151LEU A 134THR A 257ILE A 144LYS A 139 | None | 1.03A | 4o2bB-5jqeA:undetectable | 4o2bB-5jqeA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5z | PARA (Sulfolobus sp.NOB8H2) |
PF13614(AAA_31) | 5 | LEU A 36ALA A 3ALA A 156ILE A 140ILE A 124 | None | 1.03A | 4o2bB-5k5zA:3.2 | 4o2bB-5k5zA:21.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | LEU A 253MET A 257THR A 311ALA A 313ILE A 367 | None | 1.06A | 4o2bB-5mjsA:55.1 | 4o2bB-5mjsA:58.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | LEU B 255ASN B 258MET B 259THR B 314ILE B 378 | None | 0.91A | 4o2bB-5n5nB:55.9 | 4o2bB-5n5nB:97.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | LEU B 255MET B 259THR B 314ALA B 316ILE B 378 | None | 1.02A | 4o2bB-5n5nB:55.9 | 4o2bB-5n5nB:97.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t0v | IRON SULFUR CLUSTERASSEMBLY PROTEIN 1,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF01491(Frataxin_Cyay) | 5 | ALA a 150LEU a 75MET a 73ALA a 143ILE a 121 | None | 1.05A | 4o2bB-5t0va:undetectable | 4o2bB-5t0va:15.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w3j | TUBULIN BETA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | LEU B 253ASN B 256THR B 312ALA B 314ILE B 368 | None | 0.81A | 4o2bB-5w3jB:55.1 | 4o2bB-5w3jB:75.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7z | DNA POLYMERASE IIISUBUNIT BETA (Rickettsiaconorii) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | LEU A 195ALA A 200THR A 234ILE A 219ILE A 217 | None | 1.06A | 4o2bB-5w7zA:undetectable | 4o2bB-5w7zA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6h | FLAGELLAR BRAKEPROTEIN YCGR (Escherichiacoli) |
no annotation | 5 | LEU A 108LEU A 23THR A 77ALA A 75ILE A 73 | None | 0.98A | 4o2bB-5y6hA:undetectable | 4o2bB-5y6hA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ams | BETA SLIDING CLAMP (Pseudomonasaeruginosa) |
no annotation | 5 | LEU A 135THR A 228ALA A 226ILE A 224ILE A 217 | None | 1.12A | 4o2bB-6amsA:undetectable | 4o2bB-6amsA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9k | DARP14 - SUBUNIT AWITH DARPIN (syntheticconstruct) |
no annotation | 5 | LEU A 87ALA A 148LEU A 146ILE A 79ILE A 66 | None | 1.09A | 4o2bB-6c9kA:undetectable | 4o2bB-6c9kA:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c9m | N-ALPHA-ACETYLTRANSFERASE 10N-ALPHA-ACETYLTRANSFERASE 15, NATAAUXILIARY SUBUNIT (Homo sapiens) |
no annotation | 5 | LEU A 541LEU B 11ASN B 13MET B 14ALA B 6 | None | 0.90A | 4o2bB-6c9mA:undetectable | 4o2bB-6c9mA:10.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cxd | PEPTIDASE B (Yersinia pestis) |
no annotation | 5 | LEU A 244THR A 305ALA A 303ILE A 301ILE A 396 | None | 0.93A | 4o2bB-6cxdA:3.0 | 4o2bB-6cxdA:10.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d46 | BETA SLIDING CLAMP (Rickettsiatyphi) |
no annotation | 5 | LEU A 195ALA A 200THR A 234ILE A 219ILE A 217 | None | 1.05A | 4o2bB-6d46A:undetectable | 4o2bB-6d46A:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dg4 | ULP1-LIKE SUMOPROTEASE (Chaetomiumthermophilum) |
no annotation | 5 | ALA A 167THR A 139ALA A 141ILE A 143ILE A 130 | None | 0.82A | 4o2bB-6dg4A:undetectable | 4o2bB-6dg4A:10.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ey5 | T9SS COMPONENTCYTOPLASMIC MEMBRANEPROTEIN PORM (Porphyromonasgingivalis) |
no annotation | 5 | ALA A 330LEU A 328ASN A 354ILE A 365ILE A 336 | None | 1.05A | 4o2bB-6ey5A:undetectable | 4o2bB-6ey5A:10.84 |