SIMILAR PATTERNS OF AMINO ACIDS FOR 4O2B_B_LOCB503_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1al8 GLYCOLATE OXIDASE

(Spinacia
oleracea)
PF01070
(FMN_dh)
5 LEU A 298
ALA A 297
MET A  74
THR A 101
ILE A  64
None
1.08A 4o2bB-1al8A:
2.7
4o2bB-1al8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bud PROTEIN (ACUTOLYSIN
A)


(Deinagkistrodon
acutus)
PF01421
(Reprolysin)
5 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
None
1.05A 4o2bB-1budA:
undetectable
4o2bB-1budA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2r PROTEIN
(TRYPTOPHANYL TRNA
SYNTHETASE)


(Geobacillus
stearothermophilus)
PF00579
(tRNA-synt_1b)
5 LEU A 272
ALA A 220
MET A 193
ILE A 213
ILE A  16
None
1.07A 4o2bB-1d2rA:
undetectable
4o2bB-1d2rA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ej6 LAMBDA1

(Reovirus sp.)
no annotation 5 LEU B 595
ALA B 815
LEU B 549
ALA B 885
ILE B 551
None
1.07A 4o2bB-1ej6B:
undetectable
4o2bB-1ej6B:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g61 TRANSLATION
INITIATION FACTOR 6


(Methanocaldococcus
jannaschii)
PF01912
(eIF-6)
5 LEU A2020
LEU A2107
LEU A2070
ILE A2053
ILE A2084
None
0.96A 4o2bB-1g61A:
undetectable
4o2bB-1g61A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gud D-ALLOSE-BINDING
PERIPLASMIC PROTEIN


(Escherichia
coli)
PF13407
(Peripla_BP_4)
5 LEU A 188
ASN A 191
ALA A 137
ILE A 139
ILE A 197
None
1.10A 4o2bB-1gudA:
4.1
4o2bB-1gudA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h6u INTERNALIN H

(Listeria
monocytogenes)
PF08191
(LRR_adjacent)
PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13516
(LRR_6)
5 LEU A 103
ALA A  83
LEU A  53
ILE A  78
LYS A  58
None
1.00A 4o2bB-1h6uA:
undetectable
4o2bB-1h6uA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htd ATROLYSIN C

(Crotalus atrox)
PF01421
(Reprolysin)
5 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 198
None
1.07A 4o2bB-1htdA:
undetectable
4o2bB-1htdA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i6a HYDROGEN
PEROXIDE-INDUCIBLE
GENES ACTIVATOR


(Escherichia
coli)
PF03466
(LysR_substrate)
6 LEU A  93
LEU A 124
LEU A 113
MET A 112
ILE A 145
ILE A 289
None
1.49A 4o2bB-1i6aA:
undetectable
4o2bB-1i6aA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8a ENDO-1,4-BETA-XYLANA
SE A


(Thermotoga
maritima)
PF06452
(CBM9_1)
5 LEU A  52
LEU A 184
ASN A 183
ILE A 150
ILE A  25
None
0.99A 4o2bB-1i8aA:
undetectable
4o2bB-1i8aA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1izo CYTOCHROME P450
152A1


(Bacillus
subtilis)
PF00067
(p450)
5 LEU A 241
LEU A 102
LEU A 214
ALA A 218
ILE A 198
None
1.05A 4o2bB-1izoA:
undetectable
4o2bB-1izoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ko0 DIAMINOPIMELATE
DECARBOXYLASE


(Escherichia
coli)
PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N)
5 LEU A 175
LEU A 127
LEU A 185
ILE A 166
ILE A 188
None
1.11A 4o2bB-1ko0A:
undetectable
4o2bB-1ko0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l8w VLSE1

(Borreliella
burgdorferi)
PF00921
(Lipoprotein_2)
5 LEU A 286
ALA A 259
ASN A 254
ALA A 234
ILE A 231
None
0.83A 4o2bB-1l8wA:
undetectable
4o2bB-1l8wA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE


(Pseudomonas
putida)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 LEU A   8
LEU A  33
ALA A  21
ALA A 141
ILE A  11
None
None
None
FAD  A 459 (-4.5A)
FAD  A 459 (-4.5A)
1.10A 4o2bB-1lvlA:
undetectable
4o2bB-1lvlA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mus TN5 TRANSPOSASE

(Escherichia
coli)
PF01609
(DDE_Tnp_1)
PF02281
(Dimer_Tnp_Tn5)
PF14706
(Tnp_DNA_bind)
5 LEU A 356
LEU A  38
ALA A  60
ILE A  64
ILE A  46
None
1.12A 4o2bB-1musA:
undetectable
4o2bB-1musA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz3 ALPHA-L-ARABINOFURAN
OSIDASE


(Geobacillus
stearothermophilus)
PF06964
(Alpha-L-AF_C)
5 CYH A 438
LEU A 408
ASN A 427
ALA A 425
ILE A 423
None
1.12A 4o2bB-1pz3A:
undetectable
4o2bB-1pz3A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q0u BSTDEAD

(Geobacillus
stearothermophilus)
PF00270
(DEAD)
5 LEU A 185
ALA A  38
ALA A  75
ILE A  77
ILE A 129
None
1.02A 4o2bB-1q0uA:
undetectable
4o2bB-1q0uA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1soj CGMP-INHIBITED
3',5'-CYCLIC
PHOSPHODIESTERASE B


(Homo sapiens)
PF00233
(PDEase_I)
5 CYH A 929
LEU A 926
ALA A 889
LEU A 885
ILE A 806
None
1.12A 4o2bB-1sojA:
undetectable
4o2bB-1sojA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w99 PESTICIDIAL CRYSTAL
PROTEIN CRY4BA


(Bacillus
thuringiensis)
PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
5 LEU A 517
LEU A 511
ALA A 495
THR A 609
ALA A 611
None
0.90A 4o2bB-1w99A:
undetectable
4o2bB-1w99A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7n PROBABLE
NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE


(Helicobacter
pylori)
PF01729
(QRPTase_C)
PF02749
(QRPTase_N)
5 LEU A 168
ASN A 200
ALA A 203
ILE A 185
ILE A 187
None
1.01A 4o2bB-2b7nA:
undetectable
4o2bB-2b7nA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2buc DIPEPTIDYL PEPTIDASE
IV


(Sus scrofa)
PF00326
(Peptidase_S9)
PF00930
(DPPIV_N)
5 LEU A 410
LEU A 436
ASN A 437
LYS A 441
ILE A 397
None
1.11A 4o2bB-2bucA:
undetectable
4o2bB-2bucA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ec5 DERMONECROTIC TOXIN

(Pasteurella
multocida)
PF11647
(MLD)
5 LEU A1176
MET A1179
ILE A1235
LYS A1153
ILE A1148
None
1.10A 4o2bB-2ec5A:
undetectable
4o2bB-2ec5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4o 3-ISOPROPYLMALATE
DEHYDROGENASE


(Mycobacterium
tuberculosis)
PF00180
(Iso_dh)
5 LEU A  49
ASN A  59
ALA A   4
ILE A   6
ILE A  63
None
0.96A 4o2bB-2g4oA:
undetectable
4o2bB-2g4oA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gca FOLYLPOLYGLUTAMATE
SYNTHASE


(Lactobacillus
casei)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M)
5 LEU A 415
LEU A 395
THR A 337
ILE A 312
ILE A 310
None
1.06A 4o2bB-2gcaA:
3.1
4o2bB-2gcaA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2krs PROBABLE ENTEROTOXIN

(Clostridium
perfringens)
PF08239
(SH3_3)
5 LEU A  27
ASN A  12
ALA A  54
ILE A  59
ILE A  45
None
1.03A 4o2bB-2krsA:
undetectable
4o2bB-2krsA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE


(Escherichia
coli)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
PF13292
(DXP_synthase_N)
5 LEU A 242
ASN A 165
ALA A 160
ILE A 155
ILE A 127
None
1.08A 4o2bB-2o1sA:
undetectable
4o2bB-2o1sA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oox HYPOTHETICAL PROTEIN
C1556.08C IN
CHROMOSOME I


(Schizosaccharomyces
pombe)
no annotation 5 CYH G 132
LEU G 128
LEU G 167
THR G 177
ILE G 314
None
1.10A 4o2bB-2ooxG:
undetectable
4o2bB-2ooxG:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oze ORF DELTA'

(Streptococcus
pyogenes)
PF13614
(AAA_31)
5 LEU A  40
ALA A 173
THR A  78
ILE A 159
LYS A  50
None
None
AGS  A 300 ( 4.7A)
None
AGS  A 300 (-2.6A)
1.12A 4o2bB-2ozeA:
undetectable
4o2bB-2ozeA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3v INOSITOL-1-MONOPHOSP
HATASE


(Thermotoga
maritima)
PF00459
(Inositol_P)
5 LEU A1179
ALA A1113
ALA A1186
ILE A1208
ILE A1135
None
1.04A 4o2bB-2p3vA:
undetectable
4o2bB-2p3vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q42 PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 2


(Arabidopsis
thaliana)
PF00753
(Lactamase_B)
PF16123
(HAGH_C)
5 LEU A  47
ALA A  72
ASN A  63
ALA A  33
ILE A  37
None
0.98A 4o2bB-2q42A:
undetectable
4o2bB-2q42A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qs8 XAA-PRO DIPEPTIDASE

(Alteromonas
macleodii)
PF01979
(Amidohydro_1)
5 LEU A  16
LEU A  56
ALA A 385
LEU A 383
ILE A  32
None
1.07A 4o2bB-2qs8A:
2.8
4o2bB-2qs8A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5f TRANSCRIPTIONAL
REGULATOR, PUTATIVE


(Pseudomonas
syringae group
genomosp. 3)
PF04198
(Sugar-bind)
5 LEU A 283
ALA A 100
LEU A 104
ILE A 116
ILE A 114
None
1.00A 4o2bB-2r5fA:
undetectable
4o2bB-2r5fA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7b BENZOATE-COENZYME A
LIGASE


(Paraburkholderia
xenovorans)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
5 LEU A 167
LEU A  65
ALA A 123
ILE A 125
ILE A  76
None
0.88A 4o2bB-2v7bA:
undetectable
4o2bB-2v7bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xe4 OLIGOPEPTIDASE B

(Leishmania
major)
PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N)
5 LEU A 598
THR A 724
ALA A 715
ILE A 712
ILE A  79
PGR  A1742 (-4.0A)
None
None
None
None
1.04A 4o2bB-2xe4A:
2.5
4o2bB-2xe4A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yp2 HEMAGGLUTININ

(Influenza A
virus)
PF00509
(Hemagglutinin)
5 LEU A 439
ALA A 373
THR A  40
ALA A 317
ILE A 437
None
None
NAG  A 802 ( 4.0A)
None
None
1.06A 4o2bB-2yp2A:
undetectable
4o2bB-2yp2A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zci PHOSPHOENOLPYRUVATE
CARBOXYKINASE [GTP]


(Corynebacterium
glutamicum)
PF00821
(PEPCK_C)
PF17297
(PEPCK_N)
5 LEU A 252
ALA A 269
LEU A 416
ALA A 414
ILE A 412
None
1.07A 4o2bB-2zciA:
2.2
4o2bB-2zciA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zs0 EXTRACELLULAR GIANT
HEMOGLOBIN MAJOR
GLOBIN SUBUNIT B1


(Oligobrachia
mashikoi)
PF00042
(Globin)
5 LEU D 110
ALA D 113
ALA D  72
ILE D 137
ILE D  76
HEM  D 200 (-3.8A)
None
HEM  D 200 ( 4.7A)
None
None
1.07A 4o2bB-2zs0D:
undetectable
4o2bB-2zs0D:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aoe GLUTAMATE
DEHYDROGENASE


(Thermus
thermophilus)
PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N)
5 ALA A 394
THR A 205
ALA A 209
ILE A 213
ILE A 319
None
1.12A 4o2bB-3aoeA:
undetectable
4o2bB-3aoeA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3apm PROTEIN-ARGININE
DEIMINASE TYPE-4


(Homo sapiens)
PF03068
(PAD)
PF08526
(PAD_N)
PF08527
(PAD_M)
5 LEU A 462
LEU A 467
ASN A 588
ALA A 492
ILE A 546
None
1.12A 4o2bB-3apmA:
undetectable
4o2bB-3apmA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b43 TITIN

(Oryctolagus
cuniculus)
PF07679
(I-set)
5 LEU A 375
LEU A 293
LEU A 345
MET A 336
ILE A 328
None
1.11A 4o2bB-3b43A:
undetectable
4o2bB-3b43A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b59 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE


(Novosphingobium
aromaticivorans)
PF00903
(Glyoxalase)
5 ALA A 188
LEU A 147
ASN A 197
ILE A   9
ILE A  68
None
1.00A 4o2bB-3b59A:
undetectable
4o2bB-3b59A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgi PROPANEDIOL
UTILIZATION PROTEIN
PDUU


(Salmonella
enterica)
PF00936
(BMC)
5 LEU A  84
ALA A  64
THR A 110
ALA A  23
ILE A 113
None
1.07A 4o2bB-3cgiA:
undetectable
4o2bB-3cgiA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxi TOLL-LIKE RECEPTOR 4

(Homo sapiens)
PF13516
(LRR_6)
PF13855
(LRR_8)
5 LEU A 258
LEU A 208
ASN A 213
MET A 215
ILE A 218
None
0.98A 4o2bB-3fxiA:
undetectable
4o2bB-3fxiA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g85 TRANSCRIPTIONAL
REGULATOR (LACI
FAMILY)


(Clostridium
acetobutylicum)
PF13377
(Peripla_BP_3)
5 CYH A 248
LEU A 246
ALA A 185
ALA A 232
ILE A 253
None
1.02A 4o2bB-3g85A:
2.8
4o2bB-3g85A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lk6 LIPOPROTEIN YBBD

(Bacillus
subtilis)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
5 LEU A 559
ALA A 579
ASN A 595
ILE A 603
ILE A 468
None
1.01A 4o2bB-3lk6A:
6.4
4o2bB-3lk6A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjz FG41 MALONATE
SEMIALDEHYDE
DECARBOXYLASE


(coryneform
bacterium)
PF14552
(Tautomerase_2)
5 ALA A  87
LEU A  27
THR A  72
ILE A  68
ILE A   3
None
1.12A 4o2bB-3mjzA:
undetectable
4o2bB-3mjzA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3myr NICKEL-DEPENDENT
HYDROGENASE LARGE
SUBUNIT


(Allochromatium
vinosum)
PF00374
(NiFeSe_Hases)
5 LEU B1536
ALA B1021
ILE B1019
LYS B1003
ILE B1028
None
1.12A 4o2bB-3myrB:
undetectable
4o2bB-3myrB:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n92 ALPHA-AMYLASE, GH57
FAMILY


(Thermococcus
kodakarensis)
PF03065
(Glyco_hydro_57)
PF09210
(DUF1957)
5 ALA A 185
LEU A 148
ALA A 142
ILE A 179
ILE A 161
None
1.05A 4o2bB-3n92A:
undetectable
4o2bB-3n92A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3out GLUTAMATE RACEMASE

(Francisella
tularensis)
PF01177
(Asp_Glu_race)
5 LEU A 216
ASN A 219
ALA A  69
ILE A  71
ILE A   7
None
1.06A 4o2bB-3outA:
undetectable
4o2bB-3outA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr2 TRYPTOPHAN SYNTHASE
BETA CHAIN


(Salmonella
enterica)
PF00291
(PALP)
5 LEU B 271
ALA B 284
THR B 199
ALA B 191
ILE B 238
None
1.00A 4o2bB-3pr2B:
2.1
4o2bB-3pr2B:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pv2 DEGQ

(Legionella
fallonii)
PF13180
(PDZ_2)
PF13365
(Trypsin_2)
5 LEU A 115
THR A 209
ILE A 227
LYS A 180
ILE A 207
None
1.11A 4o2bB-3pv2A:
undetectable
4o2bB-3pv2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3c PROBABLE
3-HYDROXYISOBUTYRATE
DEHYDROGENASE


(Pseudomonas
aeruginosa)
PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11)
5 LEU A  40
LEU A  20
ASN A  19
MET A 154
ILE A  62
None
0.99A 4o2bB-3q3cA:
3.8
4o2bB-3q3cA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5x D-ALANINE--D-ALANINE
LIGASE


(Bacillus
anthracis)
PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C)
5 LEU A  58
LEU A  74
ALA A  50
ILE A  38
ILE A  53
None
1.06A 4o2bB-3r5xA:
undetectable
4o2bB-3r5xA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg1 CD180 MOLECULE

(Bos taurus)
PF00560
(LRR_1)
PF13855
(LRR_8)
5 LEU A 525
LEU A 498
LEU A 503
THR A 459
ILE A 486
None
1.09A 4o2bB-3rg1A:
undetectable
4o2bB-3rg1A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3si9 DIHYDRODIPICOLINATE
SYNTHASE


(Bartonella
henselae)
PF00701
(DHDPS)
5 ALA A 293
LEU A 244
ALA A 260
LYS A 263
ILE A 257
None
1.01A 4o2bB-3si9A:
3.3
4o2bB-3si9A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sz3 TRYPTOPHANYL-TRNA
SYNTHETASE


(Vibrio cholerae)
PF00579
(tRNA-synt_1b)
5 ALA A 226
ASN A 208
MET A 199
ILE A 219
ILE A  18
None
1.03A 4o2bB-3sz3A:
undetectable
4o2bB-3sz3A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3twk FORMAMIDOPYRIMIDINE-
DNA GLYCOSYLASE 1


(Arabidopsis
thaliana)
PF01149
(Fapy_DNA_glyco)
PF06831
(H2TH)
5 CYH A  18
LEU A  19
LEU A 114
LEU A  64
ILE A  84
None
1.10A 4o2bB-3twkA:
undetectable
4o2bB-3twkA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v2h D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE


(Sinorhizobium
meliloti)
PF13561
(adh_short_C2)
5 LEU A  22
MET A   0
ALA A 237
ILE A 136
ILE A  84
None
1.00A 4o2bB-3v2hA:
7.2
4o2bB-3v2hA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wtc PUTATIVE
OXIDOREDUCTASE


(Gluconobacter
oxydans)
PF00106
(adh_short)
5 LEU A  73
THR A  11
ALA A   9
ILE A   7
ILE A  33
None
0.98A 4o2bB-3wtcA:
7.1
4o2bB-3wtcA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bru ATP-DEPENDENT RNA
HELICASE DHH1


(Saccharomyces
cerevisiae)
PF00270
(DEAD)
PF00271
(Helicase_C)
5 LEU A 223
ALA A  80
ALA A 117
ILE A 119
ILE A 167
None
0.96A 4o2bB-4bruA:
undetectable
4o2bB-4bruA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3s ALDEHYDE
DEHYDROGENASE


(Lachnoclostridium
phytofermentans)
PF00171
(Aldedh)
5 ALA A  99
THR A 168
ALA A 172
ILE A 176
ILE A 143
None
1.11A 4o2bB-4c3sA:
undetectable
4o2bB-4c3sA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c90 ALPHA-GLUCURONIDASE
GH115


(Bacteroides
ovatus)
PF15979
(Glyco_hydro_115)
5 LEU A  86
THR A 100
ALA A  98
ILE A  96
ILE A 145
None
0.92A 4o2bB-4c90A:
undetectable
4o2bB-4c90A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d5r A49

(Vaccinia virus)
PF06489
(Orthopox_A49R)
5 LEU A  65
LEU A 153
ASN A 108
ILE A 146
ILE A 142
None
1.00A 4o2bB-4d5rA:
undetectable
4o2bB-4d5rA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e9o IMV MEMBRANE PROTEIN

(Vaccinia virus)
PF00194
(Carb_anhydrase)
5 LEU X  93
LEU X 159
ASN X 158
ILE X  45
ILE X 134
None
None
IOD  X 301 (-4.6A)
None
None
1.11A 4o2bB-4e9oX:
undetectable
4o2bB-4e9oX:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ezb UNCHARACTERIZED
CONSERVED PROTEIN


(Sinorhizobium
meliloti)
PF03807
(F420_oxidored)
PF09130
(DUF1932)
5 LEU A  56
THR A   3
ALA A   5
ILE A   7
ILE A  62
None
1.06A 4o2bB-4ezbA:
undetectable
4o2bB-4ezbA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krt AUTOLYTIC LYSOZYME

(Clostridium
phage phiSM101)
PF01183
(Glyco_hydro_25)
PF08239
(SH3_3)
5 CYH A 117
LEU A 121
THR A 138
ALA A 141
ILE A 169
None
1.11A 4o2bB-4krtA:
undetectable
4o2bB-4krtA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lhq CAMELID NANOBODY

(Vicugna pacos)
PF07686
(V-set)
5 CYH B  22
LEU B   4
ALA B  24
ASN B  32
ILE B  51
None
0.86A 4o2bB-4lhqB:
undetectable
4o2bB-4lhqB:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lix ENT-COPALYL
DIPHOSPHATE
SYNTHASE,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
5 LEU A 125
ALA A 121
ALA A 221
ILE A 224
ILE A 226
None
1.06A 4o2bB-4lixA:
undetectable
4o2bB-4lixA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1n SUPERANTIGEN-LIKE
PROTEIN


(Staphylococcus
aureus)
PF02876
(Stap_Strp_tox_C)
PF09199
(SSL_OB)
5 LEU A 142
ASN A 195
MET A 166
ILE A 133
ILE A 189
None
1.04A 4o2bB-4o1nA:
undetectable
4o2bB-4o1nA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1e TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT


(Escherichia
fergusonii)
PF03480
(DctP)
5 LEU A 248
LEU A  30
ASN A  31
ILE A 242
ILE A 241
None
1.11A 4o2bB-4p1eA:
undetectable
4o2bB-4p1eA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pbv NT-3 GROWTH FACTOR
RECEPTOR


(Gallus gallus)
PF00047
(ig)
PF13855
(LRR_8)
PF16920
(TPKR_C2)
5 LEU A 146
LEU A  94
ASN A 117
ILE A 132
ILE A 110
None
1.09A 4o2bB-4pbvA:
undetectable
4o2bB-4pbvA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pmh PECTINESTERASE

(Sitophilus
oryzae)
PF01095
(Pectinesterase)
5 ALA A 130
ASN A  60
ALA A  54
ILE A  51
ILE A  69
None
1.03A 4o2bB-4pmhA:
undetectable
4o2bB-4pmhA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6j LMO0131 PROTEIN

(Listeria
monocytogenes)
PF00563
(EAL)
5 LEU A  60
ALA A  62
ASN A  15
ALA A  11
ILE A   8
None
1.05A 4o2bB-4q6jA:
undetectable
4o2bB-4q6jA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7z CELL DIVISION
CONTROL PROTEIN 21


(Pyrococcus
furiosus)
PF00493
(MCM)
5 LEU A 757
ALA A 348
LEU A 344
ASN A 343
ILE A 300
None
1.12A 4o2bB-4r7zA:
undetectable
4o2bB-4r7zA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uj5 RAB-3A-INTERACTING
PROTEIN


(Homo sapiens)
no annotation 5 LEU C 333
LEU C 340
LEU C 353
ILE C 403
ILE C 355
None
1.00A 4o2bB-4uj5C:
undetectable
4o2bB-4uj5C:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y61 SLIT AND NTRK-LIKE
PROTEIN 2


(Mus musculus)
PF13855
(LRR_8)
5 LEU B 139
LEU B  91
LEU B 117
ASN B  96
ILE B 101
None
1.10A 4o2bB-4y61B:
undetectable
4o2bB-4y61B:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a9p POLYHEDRIN

(Operophtera
brumata
cypovirus 18)
PF05865
(Cypo_polyhedrin)
5 LEU A 168
LEU A 177
MET A 124
THR A 146
ILE A 111
None
1.09A 4o2bB-5a9pA:
undetectable
4o2bB-5a9pA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d0f UNCHARACTERIZED
PROTEIN


([Candida]
glabrata)
PF06202
(GDE_C)
PF14699
(hGDE_N)
PF14701
(hDGE_amylase)
PF14702
(hGDE_central)
5 LEU A 830
LEU A 734
ALA A 806
ILE A 860
ILE A 862
None
1.07A 4o2bB-5d0fA:
undetectable
4o2bB-5d0fA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gn1 ATP-DEPENDENT
HELICASE FUN30


(Saccharomyces
cerevisiae)
PF00176
(SNF2_N)
PF00271
(Helicase_C)
5 LEU A 989
LEU A 982
THR A1071
ILE A1020
ILE A 961
None
1.12A 4o2bB-5gn1A:
undetectable
4o2bB-5gn1A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr8 LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE PEPR1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
5 CYH A 338
LEU A 362
LEU A 317
LEU A 344
ILE A 331
None
1.04A 4o2bB-5gr8A:
undetectable
4o2bB-5gr8A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr8 LEUCINE-RICH REPEAT
RECEPTOR-LIKE
PROTEIN KINASE PEPR1


(Arabidopsis
thaliana)
PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8)
5 LEU A 239
LEU A 221
LEU A 226
ILE A 191
ILE A 187
None
1.11A 4o2bB-5gr8A:
undetectable
4o2bB-5gr8A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsg PUTATIVE ABC
TRANSPORTER,
NUCLEOTIDE
BINDING/ATPASE
PROTEIN


(Klebsiella
pneumoniae)
PF13407
(Peripla_BP_4)
6 LEU A  93
ALA A 118
ALA A 109
ILE A  81
LYS A 107
ILE A 114
None
1.30A 4o2bB-5hsgA:
3.9
4o2bB-5hsgA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jdd TITIN

(Homo sapiens)
PF07679
(I-set)
5 LEU A 260
LEU A 184
LEU A 234
MET A 225
ILE A 217
None
1.01A 4o2bB-5jddA:
undetectable
4o2bB-5jddA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkj ESTERASE E22

(uncultured
bacterium)
PF00561
(Abhydrolase_1)
5 LEU A 237
LEU A 244
ALA A 295
ASN A 118
ILE A 219
None
1.08A 4o2bB-5jkjA:
2.9
4o2bB-5jkjA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqe SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,CASPASE-8
CHIMERA


(Escherichia
coli)
PF01335
(DED)
PF13416
(SBP_bac_8)
5 LEU A 151
LEU A 134
THR A 257
ILE A 144
LYS A 139
None
1.03A 4o2bB-5jqeA:
undetectable
4o2bB-5jqeA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k5z PARA

(Sulfolobus sp.
NOB8H2)
PF13614
(AAA_31)
5 LEU A  36
ALA A   3
ALA A 156
ILE A 140
ILE A 124
None
1.03A 4o2bB-5k5zA:
3.2
4o2bB-5k5zA:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 LEU A 253
MET A 257
THR A 311
ALA A 313
ILE A 367
None
1.06A 4o2bB-5mjsA:
55.1
4o2bB-5mjsA:
58.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 5 LEU B 255
ASN B 258
MET B 259
THR B 314
ILE B 378
None
0.91A 4o2bB-5n5nB:
55.9
4o2bB-5n5nB:
97.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 5 LEU B 255
MET B 259
THR B 314
ALA B 316
ILE B 378
None
1.02A 4o2bB-5n5nB:
55.9
4o2bB-5n5nB:
97.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t0v IRON SULFUR CLUSTER
ASSEMBLY PROTEIN 1,
MITOCHONDRIAL


(Saccharomyces
cerevisiae)
PF01491
(Frataxin_Cyay)
5 ALA a 150
LEU a  75
MET a  73
ALA a 143
ILE a 121
None
1.05A 4o2bB-5t0va:
undetectable
4o2bB-5t0va:
15.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
5 LEU B 253
ASN B 256
THR B 312
ALA B 314
ILE B 368
None
0.81A 4o2bB-5w3jB:
55.1
4o2bB-5w3jB:
75.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7z DNA POLYMERASE III
SUBUNIT BETA


(Rickettsia
conorii)
PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3)
5 LEU A 195
ALA A 200
THR A 234
ILE A 219
ILE A 217
None
1.06A 4o2bB-5w7zA:
undetectable
4o2bB-5w7zA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6h FLAGELLAR BRAKE
PROTEIN YCGR


(Escherichia
coli)
no annotation 5 LEU A 108
LEU A  23
THR A  77
ALA A  75
ILE A  73
None
0.98A 4o2bB-5y6hA:
undetectable
4o2bB-5y6hA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ams BETA SLIDING CLAMP

(Pseudomonas
aeruginosa)
no annotation 5 LEU A 135
THR A 228
ALA A 226
ILE A 224
ILE A 217
None
1.12A 4o2bB-6amsA:
undetectable
4o2bB-6amsA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9k DARP14 - SUBUNIT A
WITH DARPIN


(synthetic
construct)
no annotation 5 LEU A  87
ALA A 148
LEU A 146
ILE A  79
ILE A  66
None
1.09A 4o2bB-6c9kA:
undetectable
4o2bB-6c9kA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT


(Homo sapiens)
no annotation 5 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
None
0.90A 4o2bB-6c9mA:
undetectable
4o2bB-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cxd PEPTIDASE B

(Yersinia pestis)
no annotation 5 LEU A 244
THR A 305
ALA A 303
ILE A 301
ILE A 396
None
0.93A 4o2bB-6cxdA:
3.0
4o2bB-6cxdA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d46 BETA SLIDING CLAMP

(Rickettsia
typhi)
no annotation 5 LEU A 195
ALA A 200
THR A 234
ILE A 219
ILE A 217
None
1.05A 4o2bB-6d46A:
undetectable
4o2bB-6d46A:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dg4 ULP1-LIKE SUMO
PROTEASE


(Chaetomium
thermophilum)
no annotation 5 ALA A 167
THR A 139
ALA A 141
ILE A 143
ILE A 130
None
0.82A 4o2bB-6dg4A:
undetectable
4o2bB-6dg4A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ey5 T9SS COMPONENT
CYTOPLASMIC MEMBRANE
PROTEIN PORM


(Porphyromonas
gingivalis)
no annotation 5 ALA A 330
LEU A 328
ASN A 354
ILE A 365
ILE A 336
None
1.05A 4o2bB-6ey5A:
undetectable
4o2bB-6ey5A:
10.84