SIMILAR PATTERNS OF AMINO ACIDS FOR 4N48_A_SAMA601_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bxn | PROTEIN (RIBULOSEBISPHOSPHATECARBOXYLASE LARGECHAIN) (Cupriavidusnecator) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | GLY A 324PRO A 154GLY A 153PHE A 151LEU A 295 | None | 1.22A | 4n48A-1bxnA:undetectable | 4n48A-1bxnA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dj3 | ADENYLOSUCCINATESYNTHETASE (Triticumaestivum) |
PF00709(Adenylsucc_synt) | 5 | GLY A 52GLY A 53ILE A 265GLY A 239LEU A 24 | None | 1.18A | 4n48A-1dj3A:undetectable | 4n48A-1dj3A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lrw | METHANOLDEHYDROGENASESUBUNIT 1 (Paracoccusdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 5 | GLY A 240GLY A 182THR A 277ASN A 261GLY A 258 | NoneNoneNone CA A 702 (-3.1A)None | 1.09A | 4n48A-1lrwA:undetectable | 4n48A-1lrwA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oi0 | HYPOTHETICAL PROTEINAF2198 (Archaeoglobusfulgidus) |
PF14464(Prok-JAB) | 5 | GLY A 67GLY A 91ILE A 14THR A 13LEU A 10 | None | 1.28A | 4n48A-1oi0A:undetectable | 4n48A-1oi0A:16.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p31 | UDP-N-ACETYLMURAMATE--ALANINE LIGASE (Haemophilusinfluenzae) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 5 | GLY A 27GLY A 25PHE A 23THR A 130GLY A 33 | EPU A 598 (-3.7A)EPU A 598 (-3.5A)NoneNoneNone | 1.12A | 4n48A-1p31A:undetectable | 4n48A-1p31A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pek | PROTEINASE K (Parengyodontiumalbum) |
PF00082(Peptidase_S8) | 5 | GLY E 75GLY E 78THR E 211ILE E 213GLY E 70 | None | 0.99A | 4n48A-1pekE:2.5 | 4n48A-1pekE:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v71 | HYPOTHETICAL PROTEINC320.14 INCHROMOSOME III (Schizosaccharomycespombe) |
PF00291(PALP) | 5 | GLY A 190GLY A 162PHE A 56GLY A 185LEU A 242 | NoneNonePLP A 350 (-4.7A)PLP A 350 (-3.4A)None | 1.07A | 4n48A-1v71A:2.2 | 4n48A-1v71A:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yb5 | QUINONEOXIDOREDUCTASE (Homo sapiens) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 320GLY A 318ILE A 188GLY A 159LEU A 163 | NAP A 801 ( 3.3A)GOL A 820 ( 3.8A)None CL A 816 ( 3.1A)None | 1.27A | 4n48A-1yb5A:6.8 | 4n48A-1yb5A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ykw | RUBISCO-LIKE PROTEIN (Chlorobaculumtepidum) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | GLY A 315PRO A 148GLY A 147PHE A 145LEU A 276 | None | 1.29A | 4n48A-1ykwA:undetectable | 4n48A-1ykwA:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yxm | PEROXISOMAL TRANS2-ENOYL COAREDUCTASE (Homo sapiens) |
PF13561(adh_short_C2) | 5 | GLY A 108GLY A 109THR A 24ILE A 47GLY A 31 | None | 0.96A | 4n48A-1yxmA:7.4 | 4n48A-1yxmA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ajr | SUGAR KINASE, PFKBFAMILY (Thermotogamaritima) |
PF00294(PfkB) | 5 | GLY A 39THR A 6LEU A 7ASN A 8ILE A 140 | ACT A 321 ( 4.3A)NoneNoneNoneNone | 1.19A | 4n48A-2ajrA:3.7 | 4n48A-2ajrA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5m | DAMAGE-SPECIFIC DNABINDING PROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | CYH A 87GLY A 106ASN A 107ILE A 79GLY A1066 | None | 1.23A | 4n48A-2b5mA:undetectable | 4n48A-2b5mA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bcc | UBIQUINOL CYTOCHROMEC OXIDOREDUCTASE (Gallus gallus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | GLY A 259PRO A 260GLY A 261THR A 156LEU A 153 | None | 0.86A | 4n48A-2bccA:undetectable | 4n48A-2bccA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cdu | NADPH OXIDASE (Lactobacillussanfranciscensis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | CYH A 242GLY A 244ILE A 240GLY A 161LEU A 164 | NoneADP A 501 (-3.0A)NoneNoneNone | 1.07A | 4n48A-2cduA:2.5 | 4n48A-2cduA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpg | SUCCINYL-COA LIGASE[GDP-FORMING]BETA-CHAIN,MITOCHONDRIAL (Sus scrofa) |
PF00549(Ligase_CoA)PF08442(ATP-grasp_2) | 5 | GLY B 328ASN B 360ILE B 339THR B 340LEU B 368 | None | 1.11A | 4n48A-2fpgB:undetectable | 4n48A-2fpgB:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9k | MODIFICATIONMETHYLASE HHAI (Haemophilushaemolyticus) |
PF00145(DNA_methylase) | 5 | GLY A 20GLY A 22PHE A 24ILE A 61THR A 62 | SAH A 328 (-3.3A)NoneSAH A 328 (-4.8A)SAH A 328 (-4.3A)SAH A 328 ( 4.3A) | 0.59A | 4n48A-2i9kA:6.9 | 4n48A-2i9kA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iu4 | DIHYDROXYACETONEKINASE (Lactococcuslactis) |
PF02733(Dak1) | 5 | GLY A 259GLY A 261ILE A 231GLY A 186LEU A 235 | None | 1.03A | 4n48A-2iu4A:undetectable | 4n48A-2iu4A:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuy | GLYCOSYLTRANSFERASE (Streptomycesviridochromogenes) |
PF00534(Glycos_transf_1) | 5 | GLY A 64GLY A 81LEU A 18ASN A 20LEU A 75 | None | 0.88A | 4n48A-2iuyA:undetectable | 4n48A-2iuyA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv2 | FORMATEDEHYDROGENASE H (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | GLY X 113GLY X 111THR X 116ASN X 114GLY X 107 | None2MD X 801 (-3.8A)NoneNoneNone | 1.15A | 4n48A-2iv2X:undetectable | 4n48A-2iv2X:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgv | TAGATOSE-6-PHOSPHATEKINASE (Staphylococcusaureus) |
PF00294(PfkB) | 5 | GLY A 36THR A 6LEU A 7ASN A 8ILE A 133 | None | 1.30A | 4n48A-2jgvA:3.7 | 4n48A-2jgvA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qkx | BIFUNCTIONAL PROTEINGLMU (Mycobacteriumtuberculosis) |
PF00132(Hexapep)PF12804(NTP_transf_3) | 5 | GLY A 15PRO A 16GLY A 17LEU A 56GLY A 113 | None | 1.23A | 4n48A-2qkxA:undetectable | 4n48A-2qkxA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4j | SULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT ALPHASULFITE REDUCTASE,DISSIMILATORY-TYPESUBUNIT BETA (Desulfovibriovulgaris;Desulfovibriovulgaris) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr)PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | GLY B 160PRO B 161LEU A 9ILE A 24LEU A 50 | None | 1.01A | 4n48A-2v4jB:undetectable | 4n48A-2v4jB:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vug | PAB1020 (Pyrococcusabyssi) |
PF09414(RNA_ligase) | 5 | GLY A 55GLY A 116LEU A 52GLY A 31LEU A 26 | None | 1.01A | 4n48A-2vugA:undetectable | 4n48A-2vugA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wa2 | NON-STRUCTURALPROTEIN 5 (Modoc virus) |
PF01728(FtsJ) | 5 | GLY A 84GLY A 86THR A 105LEU A 106THR A 134 | SAM A1248 (-3.4A)SAM A1248 (-4.4A)SAM A1248 (-4.5A)SAM A1248 (-4.1A)SAM A1248 (-3.8A) | 0.79A | 4n48A-2wa2A:16.6 | 4n48A-2wa2A:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zau | SELENIDE, WATERDIKINASE (Aquifexaeolicus) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | GLY A 296GLY A 297ILE A 62THR A 63GLY A 222 | None | 1.17A | 4n48A-2zauA:undetectable | 4n48A-2zauA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayf | NITRIC OXIDEREDUCTASE (Geobacillusstearothermophilus) |
PF00115(COX1) | 5 | GLY A 411GLY A 407ASN A 413GLY A 80LEU A 81 | None | 1.24A | 4n48A-3ayfA:undetectable | 4n48A-3ayfA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3brn | LIPOCALIN (Argasmonolakensis) |
PF02098(His_binding) | 5 | GLY A 21PRO A 22GLY A 23ILE A 82THR A 95 | NoneNoneNoneSRO A 158 (-4.4A)SRO A 158 ( 4.1A) | 1.13A | 4n48A-3brnA:undetectable | 4n48A-3brnA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5l | REGULATORY PROTEINRECX (Lactobacillusreuteri) |
PF02631(RecX) | 5 | GLY A 126PRO A 127GLY A 128LEU A 124LEU A 167 | None | 0.81A | 4n48A-3d5lA:undetectable | 4n48A-3d5lA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3evc | RNA-DIRECTED RNAPOLYMERASE NS5 (Yellow fevervirus) |
PF01728(FtsJ) | 5 | GLY A 83GLY A 85THR A 104LEU A 105ILE A 132 | SAH A 901 (-3.3A)SAH A 901 ( 4.4A)SAH A 901 (-4.5A)SAH A 901 (-4.0A)SAH A 901 (-3.8A) | 0.63A | 4n48A-3evcA:16.4 | 4n48A-3evcA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f7o | SERINE PROTEASE (Purpureocilliumlilacinum) |
PF00082(Peptidase_S8) | 5 | GLY A 78GLY A 81THR A 214ILE A 216GLY A 73 | None | 1.05A | 4n48A-3f7oA:2.7 | 4n48A-3f7oA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9i | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Rickettsiaprowazekii) |
PF13561(adh_short_C2) | 5 | GLY A 138GLY A 144ILE A 201THR A 205GLY A 179 | None | 0.94A | 4n48A-3f9iA:6.8 | 4n48A-3f9iA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9i | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Rickettsiaprowazekii) |
PF13561(adh_short_C2) | 5 | GLY A 141GLY A 144ILE A 201THR A 205GLY A 179 | None | 1.29A | 4n48A-3f9iA:6.8 | 4n48A-3f9iA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gaz | ALCOHOLDEHYDROGENASESUPERFAMILY PROTEIN (Novosphingobiumaromaticivorans) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | GLY A 96GLY A 103ILE A 136GLY A 93LEU A 285 | None | 1.10A | 4n48A-3gazA:6.8 | 4n48A-3gazA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ghy | KETOPANTOATEREDUCTASE PROTEIN (Ralstoniasolanacearum) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | CYH A 97GLY A 95PRO A 94GLY A 93ILE A 180 | None | 0.94A | 4n48A-3ghyA:3.2 | 4n48A-3ghyA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gir | AMINOMETHYLTRANSFERASE (Bartonellahenselae) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | GLY A 91THR A 190ILE A 202GLY A 172LEU A 165 | None | 1.03A | 4n48A-3girA:undetectable | 4n48A-3girA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gir | AMINOMETHYLTRANSFERASE (Bartonellahenselae) |
PF01571(GCV_T)PF08669(GCV_T_C) | 5 | GLY A 180GLY A 91ILE A 202GLY A 172LEU A 165 | None | 1.08A | 4n48A-3girA:undetectable | 4n48A-3girA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0g | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Schizosaccharomycespombe) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 5 | GLY A 407PRO A 406ASN A 400ILE A 411LEU A 432 | None | 0.95A | 4n48A-3h0gA:undetectable | 4n48A-3h0gA:12.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h1l | MITOCHONDRIALUBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEXCORE PROTEIN I (Gallus gallus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | GLY A 259PRO A 260GLY A 261THR A 156LEU A 153 | None | 0.89A | 4n48A-3h1lA:undetectable | 4n48A-3h1lA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h8t | HMUY (Porphyromonasgingivalis) |
PF14064(HmuY) | 5 | GLY A 184GLY A 187ASN A 85ILE A 147THR A 148 | None | 1.23A | 4n48A-3h8tA:undetectable | 4n48A-3h8tA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i04 | CARBON MONOXIDEDEHYDROGENASE/ACETYL-COA SYNTHASESUBUNIT BETA (Moorellathermoacetica) |
PF03063(Prismane) | 5 | GLY A 85PRO A 84GLY A 83ILE A 97GLY A 91 | None | 1.15A | 4n48A-3i04A:3.0 | 4n48A-3i04A:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6v | PERIPLASMICHIS/GLU/GLN/ARG/OPINE FAMILY-BINDINGPROTEIN (Ruegeriapomeroyi) |
PF00497(SBP_bac_3) | 5 | GLY A 75PHE A 76THR A 57ILE A 114GLY A 117 | None | 1.21A | 4n48A-3i6vA:undetectable | 4n48A-3i6vA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6v | PERIPLASMICHIS/GLU/GLN/ARG/OPINE FAMILY-BINDINGPROTEIN (Ruegeriapomeroyi) |
PF00497(SBP_bac_3) | 5 | GLY A 239PHE A 241ILE A 120THR A 121GLY A 229 | NoneNoneGOL A 280 (-4.6A)NoneNone | 0.97A | 4n48A-3i6vA:undetectable | 4n48A-3i6vA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic6 | PUTATIVE METHYLASEFAMILY PROTEIN (Neisseriagonorrhoeae) |
PF00588(SpoU_methylase) | 5 | GLY A 145GLY A 150THR A 20ILE A 45LEU A 43 | None | 1.14A | 4n48A-3ic6A:undetectable | 4n48A-3ic6A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll3 | GLUCONATE KINASE (Lactobacillusacidophilus) |
PF00370(FGGY_N)PF02782(FGGY_C) | 5 | CYH A 280GLY A 291GLY A 292GLY A 123LEU A 182 | None | 1.29A | 4n48A-3ll3A:undetectable | 4n48A-3ll3A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mqt | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Shewanellapealeana) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | CYH A 286GLY A 98THR A 262GLY A 288LEU A 292 | None | 1.10A | 4n48A-3mqtA:undetectable | 4n48A-3mqtA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nzg | PUTATIVE RACEMASE (Pseudovibriosp. JE062) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | CYH A 291GLY A 103THR A 267GLY A 293LEU A 297 | None | 1.13A | 4n48A-3nzgA:undetectable | 4n48A-3nzgA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ovg | AMIDOHYDROLASE (Mycoplasmasynoviae) |
PF02126(PTE) | 5 | GLY A 19THR A 21ILE A 64THR A 66GLY A 91 | None | 1.14A | 4n48A-3ovgA:undetectable | 4n48A-3ovgA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q75 | FARNESYLTRANSFERASEBETA SUBUNIT (Cryptococcusneoformans) |
PF00432(Prenyltrans) | 5 | GLY B 267GLY B 316PHE B 314THR B 270GLY B 333 | NoneFII B 522 ( 4.6A)NoneNoneNone | 1.25A | 4n48A-3q75B:undetectable | 4n48A-3q75B:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0z | D-SERINE DEHYDRATASE (Salmonellaenterica) |
PF00291(PALP) | 5 | GLY A 283GLY A 281THR A 43GLY A 288LEU A 291 | NoneSO4 A 449 (-3.3A)NoneNoneNone | 1.25A | 4n48A-3r0zA:2.0 | 4n48A-3r0zA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0z | D-SERINE DEHYDRATASE (Salmonellaenterica) |
PF00291(PALP) | 6 | GLY A 283PRO A 282GLY A 280LEU A 354GLY A 288LEU A 291 | NoneSO4 A 449 (-4.3A)SO4 A 449 (-3.6A)NoneNoneNone | 1.15A | 4n48A-3r0zA:2.0 | 4n48A-3r0zA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0z | D-SERINE DEHYDRATASE (Salmonellaenterica) |
PF00291(PALP) | 5 | GLY A 283PRO A 282GLY A 281GLY A 288LEU A 291 | NoneSO4 A 449 (-4.3A)SO4 A 449 (-3.3A)NoneNone | 1.04A | 4n48A-3r0zA:2.0 | 4n48A-3r0zA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r50 | IPOMOELIN (Ipomoea batatas) |
PF01419(Jacalin) | 5 | GLY A 148GLY A 14ILE A 84GLY A 135LEU A 32 | None | 0.98A | 4n48A-3r50A:undetectable | 4n48A-3r50A:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3slu | M23 PEPTIDASE DOMAINPROTEIN (Neisseriameningitidis) |
PF01551(Peptidase_M23) | 5 | GLY A 119GLY A 115ILE A 91THR A 92LEU A 78 | None | 1.06A | 4n48A-3sluA:undetectable | 4n48A-3sluA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3svt | SHORT-CHAIN TYPEDEHYDROGENASE/REDUCTASE (Mycobacteriumulcerans) |
PF13561(adh_short_C2) | 5 | GLY A 18ILE A 68THR A 69GLY A 96LEU A 118 | None | 1.16A | 4n48A-3svtA:7.7 | 4n48A-3svtA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tav | METHIONINEAMINOPEPTIDASE (Mycobacteroidesabscessus) |
PF00557(Peptidase_M24) | 5 | GLY A 114GLY A 106THR A 250LEU A 261GLY A 187 | None | 0.98A | 4n48A-3tavA:undetectable | 4n48A-3tavA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ucx | SHORT CHAINDEHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF13561(adh_short_C2) | 5 | GLY A 16PRO A 17ILE A 65THR A 66LEU A 115 | CL A 261 (-3.2A) CL A 261 ( 4.7A)NoneNoneNone | 1.06A | 4n48A-3ucxA:6.9 | 4n48A-3ucxA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9a | PUTATIVEUNCHARACTERIZEDPROTEIN (Coprinopsiscinerea) |
no annotation | 5 | GLY A 243PRO A 244GLY A 19ILE A 181GLY A 110 | None | 1.15A | 4n48A-3w9aA:undetectable | 4n48A-3w9aA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbn | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrococcusfuriosus) |
PF01554(MatE) | 5 | GLY A 158GLY A 156ILE A 85GLY A 164LEU A 12 | None | 0.66A | 4n48A-3wbnA:undetectable | 4n48A-3wbnA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wwp | (S)-HYDROXYNITRILELYASE (Baliospermummontanum) |
PF00561(Abhydrolase_1) | 5 | GLY A 81GLY A 83ILE A 157THR A 152LEU A 148 | NoneNone CL A 309 ( 4.0A)NoneNone | 1.00A | 4n48A-3wwpA:undetectable | 4n48A-3wwpA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aah | METHANOLDEHYDROGENASE (Methylophilusmethylotrophus) |
PF13360(PQQ_2) | 5 | GLY A 234GLY A 176THR A 271ASN A 255GLY A 252 | NoneNoneNone CA A 702 ( 3.0A)None | 1.02A | 4n48A-4aahA:undetectable | 4n48A-4aahA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avy | PROBABLE SHORT-CHAINDEHYDROGENASE (Pseudomonasaeruginosa) |
PF13561(adh_short_C2) | 5 | GLY A 21ILE A 62THR A 63GLY A 86LEU A 105 | None | 1.06A | 4n48A-4avyA:6.9 | 4n48A-4avyA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avy | PROBABLE SHORT-CHAINDEHYDROGENASE (Pseudomonasaeruginosa) |
PF13561(adh_short_C2) | 5 | GLY A 21LEU A 42ILE A 62THR A 63LEU A 105 | None | 1.09A | 4n48A-4avyA:6.9 | 4n48A-4avyA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ber | PHOSPHOCHOLINETRANSFERASE ANKX (Legionellapneumophila) |
PF02661(Fic)PF12796(Ank_2) | 5 | PRO A 9GLY A 10ASN A 7ILE A 59LEU A 76 | None | 0.86A | 4n48A-4berA:undetectable | 4n48A-4berA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bpt | PHENYLALANINE-4-HYDROXYLASE (PAH)(PHE-4-MONOOXYGENASE) (Legionellapneumophila) |
PF00351(Biopterin_H) | 5 | GLY A 183GLY A 181PHE A 47ILE A 188LEU A 31 | None | 1.17A | 4n48A-4bptA:undetectable | 4n48A-4bptA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxw | FACTOR XA (Pseudonajatextilis) |
PF00089(Trypsin)PF14670(FXa_inhibition) | 5 | GLY A 364PRO A 365LEU A 187THR A 216GLY A 360 | NoneNoneNoneNone0GJ A1411 (-3.8A) | 1.27A | 4n48A-4bxwA:undetectable | 4n48A-4bxwA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbz | DELTARHODOPSIN (Haloterrigenathermotolerans) |
PF01036(Bac_rhodopsin) | 5 | GLY A 30THR A 46ILE A 48THR A 88GLY A 220 | 22B A 302 (-3.6A)22B A 302 (-3.9A)NoneRET A 301 ( 4.6A)None | 1.24A | 4n48A-4fbzA:undetectable | 4n48A-4fbzA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hr6 | LECTIN (Trichosanthesanguina) |
PF00652(Ricin_B_lectin) | 5 | GLY C 52PHE C 48ASN C 97ILE C 74LEU C 33 | None | 1.25A | 4n48A-4hr6C:undetectable | 4n48A-4hr6C:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ir8 | SEDOHEPTULOSE-1,7BISPHOSPHATASE,PUTATIVE (Toxoplasmagondii) |
PF00316(FBPase) | 5 | GLY A 160PRO A 161ILE A 37GLY A 122LEU A 109 | None | 1.12A | 4n48A-4ir8A:undetectable | 4n48A-4ir8A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6o | METALLOPHOSPHOESTERASE (Ruminiclostridiumthermocellum) |
PF00149(Metallophos) | 5 | GLY A 274LEU A 272ASN A 273THR A 286LEU A 283 | None | 1.09A | 4n48A-4j6oA:undetectable | 4n48A-4j6oA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kc5 | RHIE PROTEIN (Paraburkholderiarhizoxinica) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | GLY A3851GLY A3838THR A3874LEU A3871LEU A3929 | None | 1.09A | 4n48A-4kc5A:undetectable | 4n48A-4kc5A:18.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n49 | CAP-SPECIFIC MRNA(NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF01728(FtsJ) | 12 | CYH A 277GLY A 279PRO A 280GLY A 281PHE A 283THR A 301LEU A 302ASN A 306ILE A 336THR A 337GLY A 365LEU A 383 | SAM A 601 (-3.7A)SAM A 601 (-3.5A)SAM A 601 (-3.6A)SAM A 601 (-3.6A)SAM A 601 (-3.5A)SAM A 601 (-4.1A)SAM A 601 (-4.1A)NoneSAM A 601 (-4.1A)SAM A 601 ( 3.9A)SAM A 601 ( 4.0A)SAM A 601 (-4.6A) | 0.23A | 4n48A-4n49A:68.2 | 4n48A-4n49A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n49 | CAP-SPECIFIC MRNA(NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF01728(FtsJ) | 5 | PRO A 280LEU A 302THR A 337GLY A 366LEU A 383 | SAM A 601 (-3.6A)SAM A 601 (-4.1A)SAM A 601 ( 3.9A)SAM A 601 (-4.6A)SAM A 601 (-4.6A) | 1.10A | 4n48A-4n49A:68.2 | 4n48A-4n49A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p8i | PROTEIN-GLUTAMINEGAMMA-GLUTAMYLTRANSFERASE (Bacillussubtilis) |
no annotation | 5 | GLY A 109PRO A 110GLY A 66ASN A 108ILE A 102 | None | 1.24A | 4n48A-4p8iA:undetectable | 4n48A-4p8iA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pvv | ADENOSINE KINASE (Mycobacteriumtuberculosis) |
PF00294(PfkB) | 5 | GLY A 61GLY A 58ILE A 319GLY A 266LEU A 271 | None | 0.90A | 4n48A-4pvvA:3.3 | 4n48A-4pvvA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r72 | ABC-TYPE FE3+TRANSPORT SYSTEM,PERIPLASMICCOMPONENT (Actinobacilluspleuropneumoniae) |
PF13343(SBP_bac_6) | 5 | GLY A 225PHE A 158LEU A 288GLY A 108LEU A 204 | NoneNoneGOL A 404 (-3.9A)NoneNone | 0.88A | 4n48A-4r72A:undetectable | 4n48A-4r72A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqo | METHANOLDEHYDROGENASEPROTEIN, LARGESUBUNIT (Methylococcuscapsulatus) |
no annotation | 5 | GLY B 268GLY B 210THR B 305ASN B 289GLY B 286 | NoneNoneNone CA B 701 ( 2.8A)None | 1.07A | 4n48A-4tqoB:undetectable | 4n48A-4tqoB:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4who | PROTOCATECHUATE3,4-DIOXYGENASEALPHA CHAIN (Pseudomonasputida) |
PF00775(Dioxygenase_C) | 5 | GLY A 112GLY A 77ILE A 49THR A 181GLY A 46 | None | 1.02A | 4n48A-4whoA:undetectable | 4n48A-4whoA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y9l | PROTEIN ACDH-11,ISOFORM B (Caenorhabditiselegans) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M) | 5 | GLY A 320GLY A 269ILE A 316GLY A 325LEU A 177 | None | 0.83A | 4n48A-4y9lA:undetectable | 4n48A-4y9lA:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z38 | MLNA (Bacillusvelezensis) |
no annotation | 5 | GLY A 371GLY A 351ASN A 400GLY A 368LEU A 367 | NoneNoneFMN A 900 ( 3.3A)NoneNone | 1.05A | 4n48A-4z38A:undetectable | 4n48A-4z38A:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z42 | UREASE SUBUNIT BETAUREASE SUBUNIT ALPHA (Yersiniaenterocolitica;Yersiniaenterocolitica) |
PF00699(Urease_beta)PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | GLY B 119PHE B 118THR C 73GLY C 56LEU C 51 | None | 1.21A | 4n48A-4z42B:undetectable | 4n48A-4z42B:14.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ztx | COBALAMIN-INDEPENDENT METHIONINESYNTHASE (Neurosporacrassa) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 5 | GLY A 286PRO A 287LEU A 258THR A 246GLY A 266 | None | 1.21A | 4n48A-4ztxA:undetectable | 4n48A-4ztxA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2z | EXFOLIATIVE TOXIN D2 (Staphylococcusaureus) |
PF00089(Trypsin) | 5 | GLY A 83GLY A 71THR A 93ILE A 148LEU A 270 | None | 1.19A | 4n48A-5c2zA:undetectable | 4n48A-5c2zA:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dku | PREX DNA POLYMERASE (Plasmodiumfalciparum) |
PF00476(DNA_pol_A)PF01612(DNA_pol_A_exo1) | 5 | GLY A 549GLY A 376PHE A 374THR A 526LEU A 527 | None | 1.29A | 4n48A-5dkuA:undetectable | 4n48A-5dkuA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fgw | EXTRACELLULARSTREPTODORNASE D (Streptococcuspyogenes) |
PF01223(Endonuclease_NS) | 5 | GLY A 103GLY A 101ILE A 204GLY A 106LEU A 189 | None | 1.15A | 4n48A-5fgwA:undetectable | 4n48A-5fgwA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fqd | DNA DAMAGE-BINDINGPROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | CYH A 87GLY A 106ASN A 107ILE A 79GLY A1066 | None | 1.25A | 4n48A-5fqdA:undetectable | 4n48A-5fqdA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6c | URIC ACID-XANTHINEPERMEASE (Aspergillusnidulans) |
PF00860(Xan_ur_permease) | 5 | GLY A 340PRO A 341PHE A 165THR A 195GLY A 190 | None | 1.29A | 4n48A-5i6cA:undetectable | 4n48A-5i6cA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ifz | RIBOSE 5-PHOSPHATEISOMERASE (Brucellamelitensis) |
PF02502(LacAB_rpiB) | 5 | GLY A 81GLY A 83THR A 118ILE A 75LEU A 31 | None | 1.30A | 4n48A-5ifzA:undetectable | 4n48A-5ifzA:15.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5int | PHOSPHOPANTOTHENOYLCYSTEINEDECARBOXYLASE (Bacillusanthracis) |
PF04127(DFP) | 5 | GLY A 195PRO A 196GLY A 235ILE A 271GLY A 216 | None | 1.03A | 4n48A-5intA:3.3 | 4n48A-5intA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iz3 | PREDICTED PROTEIN (Physcomitrellapatens) |
PF00316(FBPase) | 5 | GLY B 221PRO B 222ILE B 111GLY B 193LEU B 180 | None | 0.99A | 4n48A-5iz3B:undetectable | 4n48A-5iz3B:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jp5 | GALECTIN-5 (Rattusnorvegicus) |
PF00337(Gal-bind_lectin) | 5 | PRO A 127GLY A 24LEU A 123ILE A 54GLY A 51 | None | 0.93A | 4n48A-5jp5A:undetectable | 4n48A-5jp5A:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kkb | MANNOSYL-OLIGOSACCHARIDE1,2-ALPHA-MANNOSIDASE IA (Mus musculus) |
PF01532(Glyco_hydro_47) | 5 | GLY A 481GLY A 503THR A 553ILE A 551THR A 612 | None | 1.25A | 4n48A-5kkbA:undetectable | 4n48A-5kkbA:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kss | 5'-NUCLEOTIDASE SURE (Xylellafastidiosa) |
PF01975(SurE) | 5 | GLY A 105THR A 69THR A 77GLY A 113LEU A 116 | CL A 504 ( 4.9A)NoneNoneNoneNone | 1.16A | 4n48A-5kssA:undetectable | 4n48A-5kssA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mq6 | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE-LIKEPROTEIN (Thermothelomycesthermophila) |
PF07992(Pyr_redox_2) | 5 | GLY A 90GLY A 87PHE A 118LEU A 220ILE A 82 | NoneFAD A 700 (-3.5A)NoneNoneNone | 0.82A | 4n48A-5mq6A:undetectable | 4n48A-5mq6A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mu5 | UNCHARACTERIZEDPROTEIN (Magnetospirillummagneticum) |
no annotation | 5 | GLY A 457GLY A 461ASN A 458THR A 472GLY A 417 | None CL A 703 ( 3.7A)NoneNoneNone | 1.16A | 4n48A-5mu5A:undetectable | 4n48A-5mu5A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nbs | BETA-GLUCOSIDASE (Neurosporacrassa) |
no annotation | 5 | GLY A 438GLY A 421ASN A 437ILE A 442THR A 448 | NoneNoneNAG A1129 (-1.9A)NoneNone | 1.13A | 4n48A-5nbsA:3.0 | 4n48A-5nbsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nck | N-ACETYLMANNOSAMINEKINASE (Fusobacteriumnucleatum) |
PF00480(ROK) | 5 | GLY A 276GLY A 279ILE A 13THR A 32GLY A 64 | None | 1.06A | 4n48A-5nckA:undetectable | 4n48A-5nckA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xfh | SALT STRESS-INDUCEDPROTEIN (Oryza sativa) |
no annotation | 5 | GLY A 140GLY A 7ILE A 75GLY A 127LEU A 26 | None | 0.98A | 4n48A-5xfhA:undetectable | 4n48A-5xfhA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xgs | RCC1-LIKE GEXCHANGINGFACTOR-LIKE PROTEIN (Homo sapiens) |
PF00415(RCC1)PF13540(RCC1_2) | 5 | CYH A 294GLY A 292GLY A 238GLY A 308LEU A 315 | None | 1.24A | 4n48A-5xgsA:undetectable | 4n48A-5xgsA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f74 | ALCOHOL OXIDASE (Thermothelomycesthermophila) |
no annotation | 5 | GLY A 247GLY A 229THR A 250GLY A 244LEU A 489 | NoneFAD A 601 ( 4.0A)NoneNoneNone | 1.03A | 4n48A-6f74A:undetectable | 4n48A-6f74A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gkv | COCLAURINEN-METHYLTRANSFERASE (Coptis japonica) |
no annotation | 5 | GLY A 139GLY A 141THR A 160ILE A 188THR A 189 | SAH A 501 (-3.1A)NoneSAH A 501 ( 4.8A)SAH A 501 (-3.9A)None | 0.78A | 4n48A-6gkvA:7.4 | 4n48A-6gkvA:undetectable |