SIMILAR PATTERNS OF AMINO ACIDS FOR 4N16_A_CHDA301_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dnv | GALLERIA MELLONELLADENSOVIRUS CAPSIDPROTEIN (Lepidopteranambidensovirus1) |
PF02336(Denso_VP4) | 4 | ILE A 107HIS A 205HIS A 43THR A 40 | None | 0.86A | 4n16A-1dnvA:undetectable | 4n16A-1dnvA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h2a | HYDROGENASE (Desulfovibriovulgaris) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ILE S 32HIS S 45HIS S 13THR S 18 | None | 0.91A | 4n16A-1h2aS:undetectable | 4n16A-1h2aS:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 4 | ILE A 116PHE A 100THR A 66THR A 65 | None | 0.86A | 4n16A-1h7wA:undetectable | 4n16A-1h7wA:14.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jd0 | CARBONIC ANHYDRASEXII (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | AZM A1400 (-3.2A) ZN A 901 ( 3.2A) ZN A 901 ( 3.2A) ZN A 901 ( 3.1A)AZM A1400 (-3.6A)AZM A1400 (-3.3A) | 0.42A | 4n16A-1jd0A:36.7 | 4n16A-1jd0A:36.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kop | CARBONIC ANHYDRASE (Neisseriagonorrhoeae) |
PF00194(Carb_anhydrase) | 5 | GLN A 69HIS A 92HIS A 94THR A 177THR A 178 | None ZN A 301 ( 3.2A) ZN A 301 ( 3.3A)AZI A 305 (-3.4A)AZI A 305 ( 4.2A) | 1.14A | 4n16A-1kopA:29.9 | 4n16A-1kopA:33.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1kop | CARBONIC ANHYDRASE (Neisseriagonorrhoeae) |
PF00194(Carb_anhydrase) | 6 | GLN A 90HIS A 92HIS A 94HIS A 111THR A 177THR A 178 | None ZN A 301 ( 3.2A) ZN A 301 ( 3.3A) ZN A 301 ( 3.2A)AZI A 305 (-3.4A)AZI A 305 ( 4.2A) | 0.33A | 4n16A-1kopA:29.9 | 4n16A-1kopA:33.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lox | 15-LIPOXYGENASE (Oryctolaguscuniculus) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | HIS A 366HIS A 361HIS A 541PHE A 167 | FE2 A 840 (-3.4A)FE2 A 840 (-3.3A)FE2 A 840 ( 3.4A)None | 0.87A | 4n16A-1loxA:undetectable | 4n16A-1loxA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lvm | CATALYTIC DOMAIN OFTHE NUCLEARINCLUSION PROTEIN A(NIA) (Tobacco etchvirus) |
PF00863(Peptidase_C4) | 4 | ILE A 18HIS A 142HIS A 167THR A 146 | None | 0.91A | 4n16A-1lvmA:undetectable | 4n16A-1lvmA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mfl | ERB-B2 INTERACTINGPROTEIN (Homo sapiens) |
PF00595(PDZ) | 4 | ILE A1345GLN A1349PHE A1342THR A1356 | None | 0.79A | 4n16A-1mflA:undetectable | 4n16A-1mflA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pmp | P2 MYELIN PROTEIN (Bos taurus) |
PF00061(Lipocalin) | 4 | GLN A 95PHE A 70THR A 53THR A 60 | NoneNoneOLA A 200 ( 4.7A)None | 0.86A | 4n16A-1pmpA:undetectable | 4n16A-1pmpA:20.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 5 | GLN A 67HIS A 94HIS A 96THR A 199THR A 200 | None ZN A 601 ( 3.3A) ZN A 601 (-3.3A)AZM A 400 (-3.6A)AZM A 400 (-3.6A) | 1.11A | 4n16A-1rj6A:37.4 | 4n16A-1rj6A:37.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1rj6 | CARBONIC ANHYDRASEXIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | AZM A 400 (-4.3A) ZN A 601 ( 3.3A) ZN A 601 (-3.3A) ZN A 601 ( 3.2A)AZM A 400 (-3.6A)AZM A 400 (-3.6A) | 0.40A | 4n16A-1rj6A:37.4 | 4n16A-1rj6A:37.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rrh | SEED LIPOXYGENASE-3 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | GLN A 514HIS A 518HIS A 709HIS A 523 | NoneFE2 A 858 ( 3.4A)FE2 A 858 ( 3.4A)FE2 A 858 ( 3.3A) | 0.75A | 4n16A-1rrhA:undetectable | 4n16A-1rrhA:16.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1urt | CARBONIC ANHYDRASE V (Mus musculus) |
PF00194(Carb_anhydrase) | 5 | GLN A 67HIS A 94HIS A 119THR A 199THR A 200 | None ZN A 280 (-3.2A) ZN A 280 (-3.2A) ZN A 280 ( 4.9A)None | 1.35A | 4n16A-1urtA:36.7 | 4n16A-1urtA:51.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1urt | CARBONIC ANHYDRASE V (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | None ZN A 280 (-3.2A) ZN A 280 (-3.2A) ZN A 280 (-3.2A) ZN A 280 ( 4.9A)None | 0.38A | 4n16A-1urtA:36.7 | 4n16A-1urtA:51.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xt8 | PUTATIVE AMINO-ACIDTRANSPORTERPERIPLASMICSOLUTE-BINDINGPROTEIN (Campylobacterjejuni) |
PF00497(SBP_bac_3) | 4 | ILE A 195HIS A 176THR A 138THR A 139 | NoneCYS A 401 ( 4.7A)CYS A 401 (-4.4A)CYS A 401 (-3.4A) | 0.86A | 4n16A-1xt8A:undetectable | 4n16A-1xt8A:21.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y7w | HALOTOLERANTALPHA-TYPE CARBONICANHYDRASE (DCA II) (Dunaliellasalina) |
PF00194(Carb_anhydrase) | 7 | ILE A 112GLN A 113HIS A 115HIS A 117HIS A 135THR A 217THR A 218 | NoneNone ZN A 283 ( 3.2A) ZN A 283 (-3.2A) ZN A 283 ( 3.1A)ACY A 279 (-3.4A)ACY A 279 ( 4.9A) | 0.32A | 4n16A-1y7wA:26.3 | 4n16A-1y7wA:32.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1y7w | HALOTOLERANTALPHA-TYPE CARBONICANHYDRASE (DCA II) (Dunaliellasalina) |
PF00194(Carb_anhydrase) | 5 | ILE A 112GLN A 113HIS A 115HIS A 117THR A 217 | NoneNone ZN A 283 ( 3.2A) ZN A 283 (-3.2A)ACY A 279 (-3.4A) | 0.97A | 4n16A-1y7wA:26.3 | 4n16A-1y7wA:32.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2it4 | CARBONIC ANHYDRASE 1 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199 | None ZN A 561 ( 3.2A) ZN A 561 ( 3.2A) ZN A 561 ( 3.1A)PPF A 500 (-3.6A) | 0.57A | 4n16A-2it4A:41.0 | 4n16A-2it4A:60.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | GLN A 509HIS A 513HIS A 704HIS A 518 | None FE A1854 (-3.5A) FE A1854 (-3.5A) FE A1854 (-3.4A) | 0.80A | 4n16A-2iujA:undetectable | 4n16A-2iujA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ILE A 567GLN A 509HIS A 513HIS A 704 | NoneNone FE A1854 (-3.5A) FE A1854 (-3.5A) | 0.90A | 4n16A-2iujA:undetectable | 4n16A-2iujA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuk | SEED LIPOXYGENASE (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | GLN A 521HIS A 525HIS A 716HIS A 530 | None FE A 901 (-3.3A) FE A 901 (-3.5A) FE A 901 (-3.5A) | 0.87A | 4n16A-2iukA:undetectable | 4n16A-2iukA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuk | SEED LIPOXYGENASE (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | ILE A 579GLN A 521HIS A 525HIS A 716 | NoneNone FE A 901 (-3.3A) FE A 901 (-3.5A) | 0.89A | 4n16A-2iukA:undetectable | 4n16A-2iukA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pq6 | UDP-GLUCURONOSYL/UDP-GLUCOSYLTRANSFERASE (Medicagotruncatula) |
PF00201(UDPGT) | 4 | HIS A 378PHE A 202THR A 306THR A 305 | None | 0.90A | 4n16A-2pq6A:undetectable | 4n16A-2pq6A:18.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2w2j | CARBONICANHYDRASE-RELATEDPROTEIN (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | ILE A 153HIS A 118HIS A 141THR A 223 | UNX A 603 ( 4.9A) CL A 401 (-4.2A) CL A 401 (-4.1A) CL A 401 ( 4.8A) | 0.84A | 4n16A-2w2jA:37.5 | 4n16A-2w2jA:39.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsg | CCMAN5 (Cellulosimicrobiumcellulans) |
PF07971(Glyco_hydro_92) | 4 | ILE A 248HIS A 147HIS A 64PHE A 240 | None | 0.92A | 4n16A-2xsgA:undetectable | 4n16A-2xsgA:14.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yjp | PUTATIVE ABCTRANSPORTER,PERIPLASMIC BINDINGPROTEIN, AMINO ACID (Neisseriagonorrhoeae) |
PF00497(SBP_bac_3) | 4 | ILE A 223HIS A 204THR A 166THR A 167 | NoneCYS A 350 (-4.7A)CYS A 350 (-4.5A)CYS A 350 (-3.4A) | 0.81A | 4n16A-2yjpA:undetectable | 4n16A-2yjpA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zj4 | GLUCOSAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] 1 (Homo sapiens) |
PF01380(SIS) | 4 | ILE A 463GLN A 480THR A 425THR A 428 | NoneNoneAGP A 1 (-3.1A)None | 0.82A | 4n16A-2zj4A:undetectable | 4n16A-2zj4A:20.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2znc | CARBONIC ANHYDRASEIV (Mus musculus) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | None ZN A 1 ( 3.3A) ZN A 1 ( 3.3A) ZN A 1 ( 3.2A) ZN A 1 ( 4.7A)None | 0.37A | 4n16A-2zncA:32.3 | 4n16A-2zncA:35.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 6 | GLN A 115HIS A 163HIS A 165HIS A 182THR A 260THR A 261 | None ZN A 378 (-3.2A) ZN A 378 (-3.3A) ZN A 378 (-3.1A) ZN A 378 ( 4.5A)None | 1.03A | 4n16A-3b1bA:25.2 | 4n16A-3b1bA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b1b | CARBONIC ANHYDRASE 1 (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 6 | GLN A 161HIS A 163HIS A 165HIS A 182THR A 260THR A 261 | None ZN A 378 (-3.2A) ZN A 378 (-3.3A) ZN A 378 (-3.1A) ZN A 378 ( 4.5A)None | 0.31A | 4n16A-3b1bA:25.2 | 4n16A-3b1bA:25.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d5e | PLATELET-ACTIVATINGFACTORACETYLHYDROLASE (Homo sapiens) |
PF03403(PAF-AH_p_II) | 4 | ILE A 163HIS A 179HIS A 151THR A 278 | None | 0.85A | 4n16A-3d5eA:undetectable | 4n16A-3d5eA:18.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | GLN A 93HIS A 97PHE A 132THR A 200 | 4MD A 401 (-3.1A) ZN A 301 ( 3.5A)4MD A 401 (-4.6A)4MD A 401 (-3.2A) | 0.89A | 4n16A-3da2A:42.6 | 4n16A-3da2A:60.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | HIS A 95HIS A 97HIS A 120THR A 200 | ZN A 301 ( 3.6A) ZN A 301 ( 3.5A) ZN A 301 ( 3.2A)4MD A 401 (-3.2A) | 0.52A | 4n16A-3da2A:42.6 | 4n16A-3da2A:60.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da2 | CARBONIC ANHYDRASE13 (Homo sapiens) |
PF00194(Carb_anhydrase) | 4 | HIS A 97HIS A 120PHE A 132THR A 200 | ZN A 301 ( 3.5A) ZN A 301 ( 3.2A)4MD A 401 (-4.6A)4MD A 401 (-3.2A) | 0.22A | 4n16A-3da2A:42.6 | 4n16A-3da2A:60.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fe4 | CARBONIC ANHYDRASE 6 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | GLN A 109HIS A 111HIS A 113HIS A 138THR A 220 | None MG A 901 (-3.4A) MG A 901 (-3.4A) MG A 901 (-3.2A)None | 0.69A | 4n16A-3fe4A:31.4 | 4n16A-3fe4A:34.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3fe4 | CARBONIC ANHYDRASE 6 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | ILE A 259HIS A 113HIS A 138HIS A 111THR A 220 | None MG A 901 (-3.4A) MG A 901 (-3.2A) MG A 901 (-3.4A)None | 1.33A | 4n16A-3fe4A:31.4 | 4n16A-3fe4A:34.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | GLN A 67HIS A 94HIS A 96THR A 199THR A 200 | None ZN A 263 ( 3.2A) ZN A 263 ( 3.2A)AZM A 264 (-3.4A)AZM A 264 (-3.5A) | 1.09A | 4n16A-3ml5A:43.5 | 4n16A-3ml5A:55.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 7 | GLN A 92HIS A 94HIS A 96HIS A 119PHE A 131THR A 199THR A 200 | AZM A 264 (-4.1A) ZN A 263 ( 3.2A) ZN A 263 ( 3.2A) ZN A 263 ( 3.1A)AZM A 264 (-4.4A)AZM A 264 (-3.4A)AZM A 264 (-3.5A) | 0.36A | 4n16A-3ml5A:43.5 | 4n16A-3ml5A:55.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ml5 | CARBONIC ANHYDRASE 7 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | GLN A 92HIS A 94HIS A 96PHE A 131THR A 199 | AZM A 264 (-4.1A) ZN A 263 ( 3.2A) ZN A 263 ( 3.2A)AZM A 264 (-4.4A)AZM A 264 (-3.4A) | 1.24A | 4n16A-3ml5A:43.5 | 4n16A-3ml5A:55.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nr3 | PMP2 PROTEIN (Homo sapiens) |
PF00061(Lipocalin) | 4 | GLN A 96PHE A 71THR A 54THR A 61 | NoneNonePLM A 901 ( 4.6A)None | 0.87A | 4n16A-3nr3A:undetectable | 4n16A-3nr3A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oxh | RV0577 PROTEIN (Mycobacteriumtuberculosis) |
PF00903(Glyoxalase) | 4 | ILE A 116HIS A -13HIS A -12HIS A -11 | NoneNoneNonePMB A 301 (-3.1A) | 0.88A | 4n16A-3oxhA:undetectable | 4n16A-3oxhA:23.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pdi | NITROGENASE MOFECOFACTORBIOSYNTHESIS PROTEINNIFN (Azotobactervinelandii) |
PF00148(Oxidored_nitro) | 4 | ILE B 380HIS B 55PHE B 328THR B 181 | None | 0.90A | 4n16A-3pdiB:undetectable | 4n16A-3pdiB:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pp6 | SODIUM-CALCIUMEXCHANGER (Doryteuthispealeii) |
PF00061(Lipocalin) | 4 | GLN A 96PHE A 71THR A 54THR A 61 | NoneNonePAM A 133 ( 3.9A)PAM A 133 (-3.7A) | 0.91A | 4n16A-3pp6A:undetectable | 4n16A-3pp6A:16.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 6 | GLN A 102HIS A 123HIS A 125HIS A 142THR A 215THR A 216 | None ZN A 1 ( 3.2A) ZN A 1 (-3.3A) ZN A 1 ( 3.2A)MLT A 3 ( 4.3A)MLT A 3 (-2.8A) | 1.10A | 4n16A-3q31A:24.6 | 4n16A-3q31A:30.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3q31 | CARBONIC ANHYDRASE (Aspergillusoryzae) |
PF00194(Carb_anhydrase) | 6 | GLN A 121HIS A 123HIS A 125HIS A 142THR A 215THR A 216 | MLT A 3 (-3.9A) ZN A 1 ( 3.2A) ZN A 1 (-3.3A) ZN A 1 ( 3.2A)MLT A 3 ( 4.3A)MLT A 3 (-2.8A) | 0.42A | 4n16A-3q31A:24.6 | 4n16A-3q31A:30.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Sus scrofa) |
PF00305(Lipoxygenase) | 4 | HIS A 366HIS A 361HIS A 541PHE A 167 | FE2 A 1 ( 3.4A)FE2 A 1 ( 3.4A)FE2 A 1 (-3.3A)None | 0.89A | 4n16A-3rdeA:undetectable | 4n16A-3rdeA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t2c | FRUCTOSE-1,6-BISPHOSPHATEALDOLASE/PHOSPHATASE (Pyrobaculumneutrophilum) |
PF01950(FBPase_3) | 4 | ILE A 202PHE A 168THR A 152THR A 153 | None | 0.78A | 4n16A-3t2cA:undetectable | 4n16A-3t2cA:23.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uyq | CARBONIC ANHYDRASE 3 (Homo sapiens) |
PF00194(Carb_anhydrase) | 7 | GLN A 92HIS A 94HIS A 96HIS A 119PHE A 130THR A 198THR A 199 | None ZN A 261 (-3.3A) ZN A 261 (-3.3A) ZN A 261 (-3.2A)None ZN A 261 ( 4.4A)None | 0.43A | 4n16A-3uyqA:41.5 | 4n16A-3uyqA:58.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3uyq | CARBONIC ANHYDRASE 3 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | GLN A 92HIS A 94HIS A 96PHE A 130THR A 198 | None ZN A 261 (-3.3A) ZN A 261 (-3.3A)None ZN A 261 ( 4.4A) | 1.36A | 4n16A-3uyqA:41.5 | 4n16A-3uyqA:58.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wbg | FATTY ACID-BINDINGPROTEIN, HEART (Homo sapiens) |
PF00061(Lipocalin) | 4 | GLN A 95PHE A 70THR A 53THR A 60 | NoneNone2AN A 201 ( 4.0A)None | 0.84A | 4n16A-3wbgA:undetectable | 4n16A-3wbgA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x0f | CD81 ANTIGEN (Mus musculus) |
no annotation | 4 | GLN A 187HIS A 151THR A 167THR A 168 | NoneNoneIPA A 303 ( 4.1A)None | 0.91A | 4n16A-3x0fA:undetectable | 4n16A-3x0fA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq6 | PUTATIVE ARSENICALPUMP-DRIVING ATPASE (Methanothermobacterthermautotrophicus) |
PF02374(ArsA_ATPase) | 4 | GLN A 129PHE A 144THR A 135THR A 136 | None | 0.58A | 4n16A-3zq6A:undetectable | 4n16A-3zq6A:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a60 | FATTY ACID-BINDINGPROTEIN 9 TESTISLIPID-BINDINGPROTEIN, TLBP,TESTIS-TYPE FATTYACID-BINDINGPROTEIN, T-FABP (Homo sapiens) |
PF00061(Lipocalin) | 4 | GLN A 96PHE A 71THR A 54THR A 61 | None | 0.86A | 4n16A-4a60A:undetectable | 4n16A-4a60A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4azp | FATTY ACID-BINDINGPROTEIN, EPIDERMAL (Mus musculus) |
PF00061(Lipocalin) | 4 | GLN A 98PHE A 73THR A 56THR A 63 | NoneNoneA9M A1136 ( 4.3A)None | 0.82A | 4n16A-4azpA:undetectable | 4n16A-4azpA:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cns | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | ILE A 184HIS A 107PHE A 185THR A 253 | None | 0.92A | 4n16A-4cnsA:undetectable | 4n16A-4cnsA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnt | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | ILE A 184HIS A 107PHE A 185THR A 253 | None | 0.90A | 4n16A-4cntA:undetectable | 4n16A-4cntA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3l | CIRCADIAN LOCOMOTEROUTPUT CYCLESPROTEIN KAPUTBMAL1B (Mus musculus;Mus musculus) |
PF00010(HLH)PF00989(PAS)PF14598(PAS_11)PF00010(HLH)PF00989(PAS)PF14598(PAS_11) | 4 | GLN A 190HIS B 149THR A 88THR A 87 | None | 0.77A | 4n16A-4f3lA:undetectable | 4n16A-4f3lA:19.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4g7a | CARBONATEDEHYDRATASE (Sulfurihydrogenibiumsp. YO3AOP1) |
PF00194(Carb_anhydrase) | 5 | GLN A 67HIS A 89HIS A 91THR A 174THR A 175 | None ZN A 301 ( 3.2A) ZN A 301 ( 3.2A)AZM A 302 (-3.4A)AZM A 302 (-3.4A) | 1.14A | 4n16A-4g7aA:30.0 | 4n16A-4g7aA:34.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4g7a | CARBONATEDEHYDRATASE (Sulfurihydrogenibiumsp. YO3AOP1) |
PF00194(Carb_anhydrase) | 6 | GLN A 87HIS A 89HIS A 91HIS A 108THR A 174THR A 175 | AZM A 302 (-4.4A) ZN A 301 ( 3.2A) ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)AZM A 302 (-3.4A)AZM A 302 (-3.4A) | 0.28A | 4n16A-4g7aA:30.0 | 4n16A-4g7aA:34.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g7e | UREASE (Cajanus cajan) |
PF00449(Urease_alpha)PF00547(Urease_gamma)PF00699(Urease_beta)PF01979(Amidohydro_1) | 4 | ILE B 541HIS B 519PHE B 536THR B 522 | None NI B 902 (-3.2A)NoneNone | 0.90A | 4n16A-4g7eB:undetectable | 4n16A-4g7eB:15.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jqs | HYPOTHETICAL PROTEIN (Bacteroidesuniformis) |
PF06283(ThuA) | 5 | ILE A 218HIS A 120HIS A 48HIS A 234PHE A 216 | None | 0.96A | 4n16A-4jqsA:undetectable | 4n16A-4jqsA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kt1 | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 4 (Homo sapiens) |
PF01462(LRRNT)PF13516(LRR_6)PF13855(LRR_8) | 4 | ILE A 260HIS A 278PHE A 240THR A 276 | None | 0.84A | 4n16A-4kt1A:undetectable | 4n16A-4kt1A:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mda | MARINER MOS1TRANSPOSASE (Drosophilamauritiana) |
PF01359(Transposase_1) | 4 | ILE A 245HIS A 273PHE A 148THR A 135 | None | 0.90A | 4n16A-4mdaA:undetectable | 4n16A-4mdaA:23.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oua | PROTEOLYTICALLYACTIVATED FORM OFPPO4 TYROSINASE (Agaricusbisporus) |
PF00264(Tyrosinase) | 4 | HIS A 251HIS A 283HIS A 255PHE A 239 | CU1 A 402 (-3.0A)CU1 A 402 (-2.9A)CU1 A 402 (-3.1A)None | 0.88A | 4n16A-4ouaA:undetectable | 4n16A-4ouaA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q7o | IMMUNITY PROTEIN (Neisseriameningitidis) |
no annotation | 4 | ILE A 28PHE A 24THR A 46THR A 47 | None | 0.82A | 4n16A-4q7oA:undetectable | 4n16A-4q7oA:21.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 8 | ILE A 91GLN A 92HIS A 94HIS A 96HIS A 119PHE A 131THR A 199THR A 200 | NoneNone ZN A 301 (-3.2A) ZN A 301 (-3.2A) ZN A 301 (-3.1A)None ZN A 301 ( 4.4A)None | 0.36A | 4n16A-4qk3A:44.6 | 4n16A-4qk3A:95.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4qk3 | CARBONIC ANHYDRASE 2 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | ILE A 91GLN A 92HIS A 94HIS A 96PHE A 131THR A 199 | NoneNone ZN A 301 (-3.2A) ZN A 301 (-3.2A)None ZN A 301 ( 4.4A) | 1.26A | 4n16A-4qk3A:44.6 | 4n16A-4qk3A:95.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qxe | LEUCINE-RICHREPEAT-CONTAININGG-PROTEIN COUPLEDRECEPTOR 4, LINKER,VARIABLE LYMPHOCYTERECEPTOR B (Eptatretusburgeri;Homo sapiens) |
PF01462(LRRNT)PF11921(DUF3439)PF13516(LRR_6)PF13855(LRR_8) | 4 | ILE A 260HIS A 278PHE A 240THR A 276 | None | 0.81A | 4n16A-4qxeA:undetectable | 4n16A-4qxeA:19.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4uov | CARBONATEDEHYDRATASE (Thermovibrioammonificans) |
PF00194(Carb_anhydrase) | 6 | GLN A 110HIS A 112HIS A 114HIS A 131THR A 198THR A 199 | CL A 304 ( 3.7A) ZN A 298 (-3.2A) ZN A 298 ( 3.2A) ZN A 298 ( 3.2A)AZM A 299 (-3.3A)AZM A 299 (-3.3A) | 0.30A | 4n16A-4uovA:31.5 | 4n16A-4uovA:37.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wwx | V(D)JRECOMBINATION-ACTIVATING PROTEIN 1 (Mus musculus) |
PF12940(RAG1) | 4 | HIS B 942HIS B 937HIS B 744THR B 732 | ZN B1101 (-3.2A) ZN B1101 (-3.2A)NoneNone | 0.77A | 4n16A-4wwxB:undetectable | 4n16A-4wwxB:16.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 5 | GLN A 67HIS A 89HIS A 91THR A 174THR A 175 | None ZN A 301 ( 3.1A) ZN A 301 ( 3.2A)AZM A 302 (-3.3A)AZM A 302 (-3.3A) | 1.12A | 4n16A-4x5sA:30.1 | 4n16A-4x5sA:38.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4x5s | CARBONIC ANHYDRASE(CARBONATEDEHYDRATASE) (Sulfurihydrogenibiumazorense) |
PF00194(Carb_anhydrase) | 6 | GLN A 87HIS A 89HIS A 91HIS A 108THR A 174THR A 175 | AZM A 302 (-4.3A) ZN A 301 ( 3.1A) ZN A 301 ( 3.2A) ZN A 301 ( 3.2A)AZM A 302 (-3.3A)AZM A 302 (-3.3A) | 0.28A | 4n16A-4x5sA:30.1 | 4n16A-4x5sA:38.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xfw | ALPHA-CARBONICANHYDRASE (Helicobacterpylori) |
PF00194(Carb_anhydrase) | 4 | HIS A 110HIS A 112HIS A 129THR A 191 | ZN A 301 (-3.3A) ZN A 301 (-3.4A) ZN A 301 ( 3.1A) ZN A 301 (-4.3A) | 0.19A | 4n16A-4xfwA:26.6 | 4n16A-4xfwA:30.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xix | CARBONIC ANHYDRASE,ALPHA TYPE (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 5 | GLN A 138HIS A 160HIS A 162THR A 254THR A 255 | None ZN A 401 ( 3.2A) ZN A 401 ( 3.2A)2HP A 402 (-2.9A)2HP A 402 (-3.6A) | 1.05A | 4n16A-4xixA:26.0 | 4n16A-4xixA:34.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xix | CARBONIC ANHYDRASE,ALPHA TYPE (Chlamydomonasreinhardtii) |
PF00194(Carb_anhydrase) | 6 | GLN A 158HIS A 160HIS A 162HIS A 179THR A 254THR A 255 | None ZN A 401 ( 3.2A) ZN A 401 ( 3.2A) ZN A 401 ( 3.1A)2HP A 402 (-2.9A)2HP A 402 (-3.6A) | 0.26A | 4n16A-4xixA:26.0 | 4n16A-4xixA:34.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xz5 | CARBONIC ANHYDRASE,ALPHA FAMILY (Hydrogenovibriocrunogenus) |
PF00194(Carb_anhydrase) | 6 | GLN A 163HIS A 165HIS A 167HIS A 184THR A 252THR A 253 | None ZN A 401 ( 3.2A) ZN A 401 ( 3.3A) ZN A 401 ( 3.1A)BCT A 402 (-3.7A)BCT A 402 ( 4.4A) | 0.32A | 4n16A-4xz5A:30.0 | 4n16A-4xz5A:32.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ymk | ACYL-COA DESATURASE1 (Mus musculus) |
PF00487(FA_desaturase) | 4 | ILE A 50HIS A 121HIS A 116HIS A 153 | None ZN A 401 (-3.4A) ZN A 401 ( 3.5A) ZN A 401 ( 3.2A) | 0.79A | 4n16A-4ymkA:undetectable | 4n16A-4ymkA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b29 | FATTY ACID-BINDINGPROTEIN, HEART (Homo sapiens) |
PF00061(Lipocalin) | 4 | GLN A 95PHE A 70THR A 53THR A 60 | NoneNonePLM A 200 ( 4.2A)PLM A 200 ( 4.8A) | 0.85A | 4n16A-5b29A:undetectable | 4n16A-5b29A:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bvq | FATTY ACID-BINDINGPROTEIN (Pygoscelispapua) |
PF00061(Lipocalin) | 5 | ILE A 85GLN A 94PHE A 65THR A 54THR A 61 | None | 1.16A | 4n16A-5bvqA:undetectable | 4n16A-5bvqA:18.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 5 | GLN A 67HIS A 94HIS A 96THR A 199THR A 200 | GOL A 303 (-3.4A) ZN A 301 (-3.2A) ZN A 301 ( 3.2A)520 A 302 (-3.4A)GOL A 303 ( 3.5A) | 1.09A | 4n16A-5cjfA:36.9 | 4n16A-5cjfA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5cjf | CARBONIC ANHYDRASE14 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | GOL A 303 (-3.2A) ZN A 301 (-3.2A) ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)520 A 302 (-3.4A)GOL A 303 ( 3.5A) | 0.23A | 4n16A-5cjfA:36.9 | 4n16A-5cjfA:36.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5e5u | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE GAMMA (Mus musculus) |
PF00194(Carb_anhydrase) | 4 | HIS A 151PHE A 187THR A 257THR A 258 | None | 0.50A | 4n16A-5e5uA:34.3 | 4n16A-5e5uA:31.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 7 | GLN X 91HIS X 93HIS X 95HIS X 118PHE X 129THR X 197THR X 198 | None ZN X 301 (-3.2A) ZN X 301 (-3.2A) ZN X 301 (-3.1A)None ZN X 301 ( 4.4A)None | 0.35A | 4n16A-5eztX:44.4 | 4n16A-5eztX:80.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ezt | CARBONIC ANHYDRASE 2 (Bos taurus) |
PF00194(Carb_anhydrase) | 5 | GLN X 91HIS X 93HIS X 95PHE X 129THR X 197 | None ZN X 301 (-3.2A) ZN X 301 (-3.2A)None ZN X 301 ( 4.4A) | 1.35A | 4n16A-5eztX:44.4 | 4n16A-5eztX:80.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 6 | GLN A 94HIS A 96HIS A 98HIS A 115THR A 182THR A 183 | None ZN A 301 (-3.2A) ZN A 301 (-3.2A) ZN A 301 (-3.1A) ZN A 301 ( 4.4A)None | 0.39A | 4n16A-5hpjA:29.6 | 4n16A-5hpjA:35.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hpj | CARBONIC ANHYDRASE (Photobacteriumprofundum) |
PF00194(Carb_anhydrase) | 4 | HIS A 115HIS A 98THR A 182THR A 40 | ZN A 301 (-3.1A) ZN A 301 (-3.2A) ZN A 301 ( 4.4A)None | 0.90A | 4n16A-5hpjA:29.6 | 4n16A-5hpjA:35.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hql | RIBULOSEBISPHOSPHATECARBOXYLASE (Rhodopseudomonaspalustris) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | HIS A 286HIS A 322HIS A 288THR A 392 | KCX A 192 ( 3.5A)KCX A 192 (-3.8A)CAP A 500 (-3.9A)KCX A 192 ( 3.1A) | 0.91A | 4n16A-5hqlA:undetectable | 4n16A-5hqlA:18.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5jn9 | CARBONIC ANHYDRASE 4 (Homo sapiens) |
PF00194(Carb_anhydrase) | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | EZL A 302 (-4.3A) ZN A 301 ( 3.3A) ZN A 301 ( 3.3A) ZN A 301 ( 3.2A)EZL A 302 (-3.4A)EZL A 302 (-3.9A) | 0.31A | 4n16A-5jn9A:33.5 | 4n16A-5jn9A:35.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mac | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE-OXYGENASE TYPE III (Methanococcoidesburtonii) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | HIS A 286HIS A 322HIS A 288THR A 422 | KCX A 193 ( 4.3A)CAP A 501 (-4.0A)CAP A 501 (-3.8A)KCX A 193 ( 3.7A) | 0.81A | 4n16A-5macA:undetectable | 4n16A-5macA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz6 | SEPARASE (Caenorhabditiselegans) |
PF03568(Peptidase_C50) | 4 | ILE 1 41PHE 1 45THR 1 355THR 1 354 | None | 0.90A | 4n16A-5mz61:undetectable | 4n16A-5mz61:11.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr0 | SEED LINOLEATE13S-LIPOXYGENASE-1 (Glycine max) |
no annotation | 4 | GLN A 495HIS A 499HIS A 690HIS A 504 | NoneFE2 A 901 (-3.6A)FE2 A 901 (-3.6A)FE2 A 901 (-3.5A) | 0.92A | 4n16A-5tr0A:undetectable | 4n16A-5tr0A:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr0 | SEED LINOLEATE13S-LIPOXYGENASE-1 (Glycine max) |
no annotation | 4 | ILE A 553GLN A 495HIS A 499HIS A 690 | NoneNoneFE2 A 901 (-3.6A)FE2 A 901 (-3.6A) | 0.87A | 4n16A-5tr0A:undetectable | 4n16A-5tr0A:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v2d | DIOXYGENASE (Pseudomonasbrassicacearum) |
no annotation | 5 | HIS A 219HIS A 168HIS A 284PHE A 309THR A 122 | FE A 500 (-3.2A) FE A 500 (-3.3A) FE A 500 (-3.3A)NoneNone | 1.10A | 4n16A-5v2dA:undetectable | 4n16A-5v2dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v2d | DIOXYGENASE (Pseudomonasbrassicacearum) |
no annotation | 5 | HIS A 219HIS A 168HIS A 284PHE A 310THR A 122 | FE A 500 (-3.2A) FE A 500 (-3.3A) FE A 500 (-3.3A)NoneNone | 1.39A | 4n16A-5v2dA:undetectable | 4n16A-5v2dA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xoh | BERGAPTOLO-METHYLTRANSFERASE (Peucedanumpraeruptorum) |
no annotation | 4 | ILE A 213HIS A 178PHE A 193THR A 352 | None | 0.84A | 4n16A-5xohA:undetectable | 4n16A-5xohA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cg0 | V(D)JRECOMBINATION-ACTIVATING PROTEIN 1 (Mus musculus) |
no annotation | 4 | HIS A 942HIS A 937HIS A 744THR A 732 | ZN A1101 (-3.3A) ZN A1101 (-3.4A)NoneNone | 0.74A | 4n16A-6cg0A:undetectable | 4n16A-6cg0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eki | CARBONIC ANHYDRASE (Persephonellamarina) |
no annotation | 6 | GLN A 115HIS A 117HIS A 119HIS A 136THR A 202THR A 203 | None ZN A 301 (-3.3A) ZN A 301 (-3.3A) ZN A 301 (-3.2A) ZN A 301 (-4.4A)None | 0.25A | 4n16A-6ekiA:30.0 | 4n16A-6ekiA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 4 | ILE A 213HIS A 282PHE A 135THR A 342 | None | 0.84A | 4n16A-6eojA:undetectable | 4n16A-6eojA:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fe1 | CARBONIC ANHYDRASE 9 (Homo sapiens) |
no annotation | 6 | GLN A 92HIS A 94HIS A 96HIS A 119THR A 199THR A 200 | V14 A 302 (-3.8A) ZN A 301 ( 3.2A) ZN A 301 ( 3.2A) ZN A 301 ( 3.1A)V14 A 302 (-3.2A)V14 A 302 (-3.5A) | 0.38A | 4n16A-6fe1A:34.0 | 4n16A-6fe1A:undetectable |