SIMILAR PATTERNS OF AMINO ACIDS FOR 4N09_C_ADNC401_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6j NITROGEN REGULATORY
IIA PROTEIN

(Escherichia
coli) 		PF00359
(PTS_EIIA_2) 		4 ASN A  15
LEU A  14
SER A  12
LEU A 110
 None
 1.26A 4n09C-1a6jA:
undetectable		 4n09C-1a6jA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ez4 LACTATE
DEHYDROGENASE

(Lactobacillus
pentosus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ASN A 113
LEU A 143
SER A 118
LEU A 329
 NAD  A1352 ( 4.7A)
None
None
None
 1.28A 4n09C-1ez4A:
6.3		 4n09C-1ez4A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 ASN A1121
LEU A1123
SER A1139
LEU A1136
 None
 1.07A 4n09C-1jl5A:
undetectable		 4n09C-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis) 		PF12468
(TTSSLRR) 		4 ASN A1267
LEU A1269
SER A1285
LEU A1282
 None
 1.09A 4n09C-1jl5A:
undetectable		 4n09C-1jl5A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k6y INTEGRASE

(Human
immunodeficiency
virus 1) 		PF00665
(rve)
PF02022
(Integrase_Zn) 		4 ASN A  27
LEU A  28
SER A  24
ASN A  18
 None
 1.23A 4n09C-1k6yA:
undetectable		 4n09C-1k6yA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pc3 PHOSPHATE-BINDING
PROTEIN 1

(Mycobacterium
tuberculosis) 		PF12849
(PBP_like_2) 		4 ASN A  43
LEU A  44
LEU A 326
ASN A 321
 None
 1.23A 4n09C-1pc3A:
undetectable		 4n09C-1pc3A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfx PROTEIN (PH 2.5 ACID
PHOSPHATASE)

(Aspergillus
niger) 		PF00328
(His_Phos_2) 		4 ASN A 414
SER A 409
LEU A 299
ASN A 303
 None
 1.29A 4n09C-1qfxA:
undetectable		 4n09C-1qfxA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpw PORCINE HEMOGLOBIN
(ALPHA SUBUNIT)

(Sus scrofa) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 650 ( 4.8A)
 0.91A 4n09C-1qpwA:
undetectable		 4n09C-1qpwA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v2d GLUTAMINE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 ASN A 159
LEU A 157
SER A 190
LEU A  94
 PLP  A 510 (-3.3A)
None
None
None
 1.24A 4n09C-1v2dA:
3.6		 4n09C-1v2dA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2au3 DNA PRIMASE

(Aquifex
aeolicus) 		PF01807
(zf-CHC2)
PF08275
(Toprim_N)
PF13155
(Toprim_2) 		4 ASN A 159
LEU A 161
LEU A 107
ASN A 170
 None
 1.24A 4n09C-2au3A:
undetectable		 4n09C-2au3A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ba0 ARCHAEAL EXOSOME RNA
BINDING PROTEIN RRP4

(Archaeoglobus
fulgidus) 		PF00575
(S1)
PF14382
(ECR1_N)
PF15985
(KH_6) 		4 ASN A  90
LEU A  85
SER A  88
LEU A 114
 None
 1.14A 4n09C-2ba0A:
undetectable		 4n09C-2ba0A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eig LECTIN

(Lotus
tetragonolobus) 		PF00139
(Lectin_legB) 		4 ASN A  58
LEU A 227
SER A  61
LEU A 192
 None
 1.28A 4n09C-2eigA:
undetectable		 4n09C-2eigA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF16073
(SAT) 		4 ASN B 165
LEU B 421
LEU B 339
ASN B 390
 None
 1.30A 4n09C-2pffB:
undetectable		 4n09C-2pffB:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qsd UNCHARACTERIZED
CONSERVED PROTEIN

(Idiomarina
loihiensis) 		PF07566
(DUF1543) 		4 ASN A   6
LEU A  71
SER A  73
LEU A 150
 None
 1.23A 4n09C-2qsdA:
undetectable		 4n09C-2qsdA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3s UNCHARACTERIZED
PROTEIN

(Nostoc
punctiforme) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		4 ASN A 206
LEU A 177
SER A 174
ASN A 239
 None
None
EDO  A 337 (-3.6A)
CL  A 335 ( 4.3A)
 1.26A 4n09C-2r3sA:
4.0		 4n09C-2r3sA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxb DNA REPAIR PROTEIN
RHP9

(Schizosaccharomyces
pombe) 		PF00533
(BRCT) 		4 ASN A  85
LEU A 158
SER A  83
LEU A  51
 None
 1.31A 4n09C-2vxbA:
undetectable		 4n09C-2vxbA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1j CELL CYCLE
CHECKPOINT PROTEIN
RAD1

(Homo sapiens) 		PF02144
(Rad1) 		4 ASN C  26
LEU C  21
SER C  28
LEU C 123
 None
 1.20A 4n09C-3a1jC:
undetectable		 4n09C-3a1jC:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN B 413
LEU B 415
SER B 437
ASN B 483
 None
None
NAG  B 972 ( 4.2A)
None
 1.12A 4n09C-3a79B:
undetectable		 4n09C-3a79B:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a79 TOLL-LIKE RECEPTOR
6, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Mus musculus) 		PF11921
(DUF3439)
PF13855
(LRR_8) 		4 ASN B 413
LEU B 415
SER B 437
LEU B 457
 None
None
NAG  B 972 ( 4.2A)
None
 1.31A 4n09C-3a79B:
undetectable		 4n09C-3a79B:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3acz METHIONINE
GAMMA-LYASE

(Entamoeba
histolytica) 		PF01053
(Cys_Met_Meta_PP) 		4 ASN A 208
SER A 202
LEU A 333
ASN A 155
 None
LLP  A 205 ( 2.8A)
LLP  A 205 ( 4.3A)
SO4  A2001 (-3.3A)
 1.09A 4n09C-3aczA:
undetectable		 4n09C-3aczA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1a HEMOGLOBIN SUBUNIT
ALPHA-1/2

(Capra hircus) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 142 ( 4.8A)
 1.04A 4n09C-3d1aA:
undetectable		 4n09C-3d1aA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqx FIC DOMAIN
CONTAINING
TRANSCRIPTIONAL
REGULATOR

(Shewanella
oneidensis) 		PF02661
(Fic)
PF13784
(Fic_N) 		4 ASN A  53
LEU A  56
LEU A 359
ASN A 365
 None
 1.23A 4n09C-3eqxA:
undetectable		 4n09C-3eqxA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdj HEMOGLOBIN SUBUNIT
ALPHA

(Camelus
dromedarius) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
None
HEM  A 142 ( 4.7A)
 0.97A 4n09C-3gdjA:
undetectable		 4n09C-3gdjA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ib3 COCE/NOND FAMILY
HYDROLASE

(Staphylococcus
aureus) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		4 ASN A  35
SER A  30
LEU A   5
ASN A 116
 None
 1.24A 4n09C-3ib3A:
3.1		 4n09C-3ib3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j7e H16.V5 FAB LIGHT
CHAIN

(Mus musculus) 		no annotation 4 ASN L  37
LEU L  39
SER L  58
LEU L  79
 None
 1.20A 4n09C-3j7eL:
undetectable		 4n09C-3j7eL:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jav INOSITOL
1,4,5-TRISPHOSPHATE
RECEPTOR TYPE 1

(Rattus
norvegicus) 		PF00520
(Ion_trans)
PF01365
(RYDR_ITPR)
PF02815
(MIR)
PF08454
(RIH_assoc)
PF08709
(Ins145_P3_rec) 		4 ASN A 229
LEU A 111
SER A 227
LEU A   9
 None
 1.03A 4n09C-3javA:
undetectable		 4n09C-3javA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jck 26S PROTEASOME
REGULATORY SUBUNIT
RPN3

(Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF08375
(Rpn3_C) 		4 ASN A 280
LEU A 276
SER A 251
LEU A 257
 None
 1.16A 4n09C-3jckA:
undetectable		 4n09C-3jckA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k55 BETA-HEMOLYSIN

(Staphylococcus
aureus) 		PF03372
(Exo_endo_phos) 		4 ASN A 198
LEU A 245
SER A 223
ASN A 230
 None
 1.23A 4n09C-3k55A:
undetectable		 4n09C-3k55A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l78 REGULATORY PROTEIN
SPX

(Streptococcus
mutans) 		PF03960
(ArsC) 		4 ASN A  86
LEU A  89
SER A  84
LEU A  79
 None
 1.27A 4n09C-3l78A:
undetectable		 4n09C-3l78A:
15.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae) 		PF00294
(PfkB) 		4 ASN A  14
LEU A  16
SER A  65
ASN A 296
 B4P  A 349 ( 4.0A)
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-3.6A)
 0.88A 4n09C-3looA:
48.0		 4n09C-3looA:
36.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3loo ANOPHELES GAMBIAE
ADENOSINE KINASE

(Anopheles
gambiae) 		PF00294
(PfkB) 		4 ASN A  14
LEU A  16
SER A  65
LEU A 133
 B4P  A 349 ( 4.0A)
B4P  A 349 (-4.7A)
CL  A 351 ( 4.6A)
B4P  A 349 (-4.5A)
 0.50A 4n09C-3looA:
48.0		 4n09C-3looA:
36.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzn GLUCARATE
DEHYDRATASE

(Chromohalobacter
salexigens) 		PF13378
(MR_MLE_C) 		4 ASN A 285
LEU A 307
SER A 336
LEU A 144
 None
None
None
ACT  A 452 ( 4.2A)
 1.29A 4n09C-3mznA:
3.4		 4n09C-3mznA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n27 FUSION GLYCOPROTEIN
F0, LINKER, FUSION
GLYCOPROTEIN F0

(Hendra
henipavirus;
Nipah
henipavirus) 		PF00523
(Fusion_gly) 		4 ASN A   9
SER A  13
LEU A  76
ASN A  19
 None
 1.19A 4n09C-3n27A:
undetectable		 4n09C-3n27A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op9 PLI0006 PROTEIN

(Listeria
innocua) 		PF01381
(HTH_3) 		4 ASN A  10
LEU A  14
SER A  12
ASN A  22
 None
 1.12A 4n09C-3op9A:
undetectable		 4n09C-3op9A:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3otx ADENOSINE KINASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00294
(PfkB) 		4 ASN A  13
LEU A  15
SER A  64
LEU A 134
 AP5  A 346 (-4.1A)
AP5  A 346 (-4.4A)
NA  A 347 (-4.8A)
AP5  A 346 ( 4.4A)
 0.20A 4n09C-3otxA:
58.3		 4n09C-3otxA:
99.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1u PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE

(Azotobacter
vinelandii) 		PF00160
(Pro_isomerase) 		4 ASN A 105
LEU A 108
SER A  77
ASN A  74
 None
 1.18A 4n09C-3t1uA:
undetectable		 4n09C-3t1uA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3unv ADMH

(Pantoea
agglomerans) 		PF00221
(Lyase_aromatic) 		4 ASN A 143
LEU A 218
LEU A 179
ASN A 106
 None
 1.21A 4n09C-3unvA:
undetectable		 4n09C-3unvA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vre HEMOGLOBIN SUBUNIT
ALPHA

(Mammuthus
primigenius) 		PF00042
(Globin) 		4 ASN A 131
LEU A  76
SER A 133
LEU A  66
 None
None
HEM  A 201 ( 4.2A)
None
 1.30A 4n09C-3vreA:
undetectable		 4n09C-3vreA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnp CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Bacillus
circulans) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 LEU A 628
SER A 634
LEU A 661
ASN A 640
 None
 1.30A 4n09C-3wnpA:
undetectable		 4n09C-3wnpA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 529
LEU A 531
SER A 551
LEU A 548
 None
 1.19A 4n09C-3wpeA:
undetectable		 4n09C-3wpeA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwh (R)-AMINE
TRANSAMINASE

(Arthrobacter
sp. KNK168) 		PF01063
(Aminotran_4) 		4 ASN A 296
LEU A 273
SER A 292
LEU A 211
 None
 1.01A 4n09C-3wwhA:
undetectable		 4n09C-3wwhA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdr ALCOHOL
DEHYDROGENASE DOMAIN
OF THE BIFUNCTIONAL
ACETALDEHYDE
DEHYDROGENASE

(Parageobacillus
thermoglucosidasius) 		PF00465
(Fe-ADH) 		4 ASN A 712
LEU A 689
SER A 714
LEU A 694
 None
 1.07A 4n09C-3zdrA:
3.5		 4n09C-3zdrA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxx TRANSCRIPTION FACTOR
BYE1

(Saccharomyces
cerevisiae) 		PF07500
(TFIIS_M) 		4 ASN X 281
LEU X 332
LEU X 309
ASN X 339
 None
 1.09A 4n09C-4bxxX:
undetectable		 4n09C-4bxxX:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cak INTEGRIN ALPHA-IIB

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ASN A 629
LEU A 631
SER A 706
LEU A 653
 None
 0.94A 4n09C-4cakA:
undetectable		 4n09C-4cakA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvu BETA-MANNOSIDASE

(Trichoderma
harzianum) 		PF00703
(Glyco_hydro_2) 		4 ASN A 593
LEU A 704
LEU A 389
ASN A 709
 None
 1.28A 4n09C-4cvuA:
undetectable		 4n09C-4cvuA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvj PUTATIVE
ZINC-DEPENDENT
ALCOHOL
DEHYDROGENASE
PROTEIN

(Rhizobium etli) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		4 ASN A 328
LEU A 330
LEU A 338
ASN A 121
 None
 1.04A 4n09C-4dvjA:
4.6		 4n09C-4dvjA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e7n SNAKE-VENOM
THROMBIN-LIKE ENZYME

(Gloydius halys) 		PF00089
(Trypsin) 		4 ASN A 161
LEU A 163
SER A 134
LEU A 181
 None
 1.22A 4n09C-4e7nA:
undetectable		 4n09C-4e7nA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4egf L-XYLULOSE REDUCTASE

(Mycolicibacterium
smegmatis) 		PF13561
(adh_short_C2) 		4 LEU A 185
SER A 134
LEU A  98
ASN A 100
 None
 1.30A 4n09C-4egfA:
6.7		 4n09C-4egfA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fho INTERNALIN C2

(Listeria
monocytogenes) 		PF12354
(Internalin_N)
PF12799
(LRR_4)
PF13516
(LRR_6) 		4 ASN A 130
LEU A 132
SER A 151
ASN A 196
 None
 0.94A 4n09C-4fhoA:
undetectable		 4n09C-4fhoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g8t GLUCARATE
DEHYDRATASE

(Actinobacillus
succinogenes) 		PF13378
(MR_MLE_C) 		4 ASN A 285
LEU A 307
SER A 336
LEU A 144
 NA  A 502 (-3.3A)
None
None
None
 1.26A 4n09C-4g8tA:
undetectable		 4n09C-4g8tA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gq2 NUCLEOPORIN NUP120

(Schizosaccharomyces
pombe) 		PF11715
(Nup160) 		4 ASN M 836
LEU M 835
LEU M 815
ASN M 737
 None
 1.16A 4n09C-4gq2M:
undetectable		 4n09C-4gq2M:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i93 PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE
AT5G41260

(Arabidopsis
thaliana) 		PF07714
(Pkinase_Tyr) 		4 ASN A 183
LEU A 241
SER A 237
LEU A 168
 None
 1.14A 4n09C-4i93A:
undetectable		 4n09C-4i93A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED

(Xanthomonas
oryzae) 		PF01053
(Cys_Met_Meta_PP) 		4 ASN B 213
SER B 207
LEU B 340
ASN B 160
 None
LLP  B 210 ( 2.6A)
LLP  B 210 (-4.3A)
NAK  B 402 (-3.3A)
 1.12A 4n09C-4iyoB:
undetectable		 4n09C-4iyoB:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l6r SOLUBLE CYTOCHROME
B562 AND GLUCAGON
RECEPTOR CHIMERA

(Escherichia
coli;
Homo sapiens) 		PF00002
(7tm_2)
PF07361
(Cytochrom_B562) 		4 ASN A 174
LEU A 163
SER A 167
LEU A 411
 None
 1.30A 4n09C-4l6rA:
undetectable		 4n09C-4l6rA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lct COP9 SIGNALOSOME
COMPLEX SUBUNIT 1

(Arabidopsis
thaliana) 		PF01399
(PCI)
PF10602
(RPN7) 		4 ASN A 320
LEU A 321
SER A 316
LEU A 298
 None
 1.14A 4n09C-4lctA:
undetectable		 4n09C-4lctA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lhe THERMOSTABLE
MONOACYLGLYCEROL
LIPASE

(Bacillus sp.
H-257) 		PF12146
(Hydrolase_4) 		4 ASN A 151
LEU A 149
SER A 224
ASN A 120
 None
 0.96A 4n09C-4lheA:
5.4		 4n09C-4lheA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lu1 MAF-LIKE PROTEIN
YCEF

(Escherichia
coli) 		PF02545
(Maf) 		4 ASN A  87
LEU A  90
SER A 150
LEU A  74
 None
 1.31A 4n09C-4lu1A:
undetectable		 4n09C-4lu1A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lxr PROTEIN TOLL

(Drosophila
melanogaster) 		PF00560
(LRR_1)
PF01462
(LRRNT)
PF13306
(LRR_5)
PF13855
(LRR_8) 		4 ASN A 702
LEU A 704
SER A 722
LEU A 719
 None
 1.11A 4n09C-4lxrA:
undetectable		 4n09C-4lxrA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4piv FATTY ACID SYNTHASE

(Homo sapiens) 		PF08242
(Methyltransf_12)
PF08659
(KR) 		4 LEU A1259
SER A1254
LEU A1219
ASN A1316
 None
 1.25A 4n09C-4pivA:
4.7		 4n09C-4pivA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9t NUCLEOPORIN NUP133

(Vanderwaltozyma
polyspora) 		PF08801
(Nucleoporin_N) 		4 ASN A 204
SER A 136
LEU A 194
ASN A 187
 None
 1.02A 4n09C-4q9tA:
undetectable		 4n09C-4q9tA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 ASN A2362
LEU A2417
LEU A2427
ASN A2199
 None
 0.96A 4n09C-4rh7A:
undetectable		 4n09C-4rh7A:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u06 LIC10831

(Leptospira
interrogans) 		PF12799
(LRR_4)
PF13855
(LRR_8) 		4 ASN A  79
LEU A  81
SER A 101
ASN A 148
 None
 1.19A 4n09C-4u06A:
undetectable		 4n09C-4u06A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u09 LIC12759

(Leptospira
interrogans) 		PF13855
(LRR_8) 		4 ASN A 143
LEU A 145
SER A 165
ASN A 212
 None
 1.17A 4n09C-4u09A:
undetectable		 4n09C-4u09A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xr7 PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3

(Saccharomyces
cerevisiae) 		no annotation 4 ASN L 420
LEU L 421
SER L 418
ASN L 350
 None
 1.22A 4n09C-4xr7L:
undetectable		 4n09C-4xr7L:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5c LRRTM

(synthetic
construct) 		PF13855
(LRR_8) 		4 ASN A  64
LEU A  66
SER A  87
ASN A 136
 None
 1.12A 4n09C-5a5cA:
undetectable		 4n09C-5a5cA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bop OCTARELLIN V.1

(synthetic
construct) 		no annotation 4 LEU B 122
SER B 140
LEU B 137
ASN B  38
 None
 1.16A 4n09C-5bopB:
4.6		 4n09C-5bopB:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cv1 P GRANULE
ABNORMALITY PROTEIN
1

(Caenorhabditis
elegans) 		no annotation 4 LEU A 454
SER A 456
LEU A 360
ASN A 424
 None
 1.23A 4n09C-5cv1A:
undetectable		 4n09C-5cv1A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5df0 AC-CHIA

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF00704
(Glyco_hydro_18)
PF08329
(ChitinaseA_N) 		4 LEU A 171
SER A 175
LEU A 538
ASN A 542
 None
 1.03A 4n09C-5df0A:
undetectable		 4n09C-5df0A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmy BETA-GALACTOSIDASE

(Bifidobacterium
bifidum) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		4 ASN A 392
SER A 164
LEU A 161
ASN A 159
 None
 1.11A 4n09C-5dmyA:
undetectable		 4n09C-5dmyA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do7 ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
5

(Homo sapiens) 		PF00005
(ABC_tran)
PF01061
(ABC2_membrane) 		4 ASN A 578
LEU A 575
SER A 503
ASN A 393
 None
 1.22A 4n09C-5do7A:
undetectable		 4n09C-5do7A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 ASN A 250
SER A 218
LEU A 613
ASN A 617
 None
 0.98A 4n09C-5fjiA:
undetectable		 4n09C-5fjiA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gj8 ACYL-COA
DEHYDROGENASE TYPE 2
DOMAIN PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
PF08028
(Acyl-CoA_dh_2) 		4 LEU A 166
SER A 211
LEU A  89
ASN A 372
 None
 1.16A 4n09C-5gj8A:
undetectable		 4n09C-5gj8A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gs7 CHOLOYLGLYCINE
HYDROLASE

(Enterococcus
faecalis) 		PF02275
(CBAH) 		4 ASN A  79
LEU A 138
LEU A 135
ASN A 126
 None
 1.25A 4n09C-5gs7A:
undetectable		 4n09C-5gs7A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb1 NUCLEOPORIN NUP170

(Chaetomium
thermophilum) 		PF03177
(Nucleoporin_C) 		4 LEU A1244
SER A1246
LEU A1291
ASN A1252
 None
 1.22A 4n09C-5hb1A:
undetectable		 4n09C-5hb1A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hke BILE SALT HYDROLASE

(Lactobacillus
salivarius) 		PF02275
(CBAH) 		4 ASN A  79
LEU A 139
LEU A 136
ASN A 127
 OCS  A   2 ( 3.7A)
None
None
None
 1.26A 4n09C-5hkeA:
undetectable		 4n09C-5hkeA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hsi PUTATIVE
DECARBOXYLASE

(Lactobacillus
brevis) 		PF00282
(Pyridoxal_deC) 		4 ASN A 112
LEU A 109
SER A 448
LEU A 104
 None
 1.31A 4n09C-5hsiA:
undetectable		 4n09C-5hsiA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxt (2Z,6Z)-FARNESYL
DIPHOSPHATE
SYNTHASE,
CHLOROPLASTIC

(Solanum
habrochaites) 		PF01255
(Prenyltransf) 		4 ASN A 200
LEU A 199
SER A 131
LEU A 145
 None
None
IPR  A 403 (-2.9A)
None
 1.11A 4n09C-5hxtA:
undetectable		 4n09C-5hxtA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijg CYS/MET METABOLISM
PYRIDOXAL-PHOSPHATE-
DEPENDENT ENZYME

(Brucella
melitensis) 		PF01053
(Cys_Met_Meta_PP) 		4 ASN A 185
LEU A 219
SER A 189
LEU A 320
 None
 1.13A 4n09C-5ijgA:
undetectable		 4n09C-5ijgA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irm UNCHARACTERIZED
PROTEIN

(Oryctolagus
cuniculus) 		PF05729
(NACHT)
PF13516
(LRR_6) 		4 ASN A 945
LEU A 947
SER A 971
LEU A 968
 None
 1.29A 4n09C-5irmA:
undetectable		 4n09C-5irmA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ix8 PUTATIVE SUGAR ABC
TRANSPORT SYSTEM,
SUBSTRATE-BINDING
PROTEIN

(Bordetella
parapertussis) 		PF13407
(Peripla_BP_4) 		4 ASN A 149
SER A 322
LEU A 158
ASN A 329
 None
 1.27A 4n09C-5ix8A:
undetectable		 4n09C-5ix8A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j2s KILLER CELL
LECTIN-LIKE RECEPTOR
SUBFAMILY B MEMBER
1B ALLELE A

(Rattus
norvegicus) 		no annotation 4 ASN A 174
LEU A 173
SER A 171
LEU A 131
 None
None
NAG  A 301 (-3.1A)
NAG  A 301 (-3.8A)
 1.27A 4n09C-5j2sA:
undetectable		 4n09C-5j2sA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kca CEREBELLIN-1,CEREBEL
LIN-1,CEREBELLIN-1,G
LUTAMATE RECEPTOR
IONOTROPIC, DELTA-2

(Homo sapiens) 		PF00386
(C1q)
PF01094
(ANF_receptor) 		4 ASN A 822
LEU A 819
SER A 865
ASN A 881
 None
 1.30A 4n09C-5kcaA:
undetectable		 4n09C-5kcaA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m23 WD REPEAT-CONTAINING
PROTEIN 5

(Homo sapiens) 		PF00400
(WD40) 		4 ASN A 100
LEU A 101
SER A  97
ASN A 138
 None
 0.96A 4n09C-5m23A:
undetectable		 4n09C-5m23A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu7 COATOMER SUBUNIT
BETA
COATOMER SUBUNIT
DELTA-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF01217
(Clat_adaptor_s)
PF01602
(Adaptin_N) 		4 LEU A 251
SER A 266
LEU A 224
ASN B  75
 None
 1.21A 4n09C-5mu7A:
undetectable		 4n09C-5mu7A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9z PHOSPHOGLYCEROL
TRANSFERASE

(Streptococcus
pyogenes) 		no annotation 4 ASN A 779
SER A 782
LEU A 799
ASN A 545
 None
 1.04A 4n09C-5u9zA:
2.0		 4n09C-5u9zA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vsj ALPHA-1,4-GLUCAN:MAL
TOSE-1-PHOSPHATE
MALTOSYLTRANSFERASE
1

(Streptomyces
coelicolor) 		PF00128
(Alpha-amylase)
PF11896
(DUF3416) 		4 ASN A 519
LEU A 482
LEU A 522
ASN A 267
 None
 1.10A 4n09C-5vsjA:
undetectable		 4n09C-5vsjA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vzj EXOSOME COMPLEX
EXONUCLEASE RRP6

(Saccharomyces
cerevisiae) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		4 ASN J 497
LEU J 501
LEU J 468
ASN J 488
 None
 0.98A 4n09C-5vzjJ:
undetectable		 4n09C-5vzjJ:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x0y TRANSCRIPTION
REGULATORY PROTEIN
SNF2

(Saccharomyces
cerevisiae) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		4 LEU O1133
SER O1143
LEU O1172
ASN O1150
 None
 1.26A 4n09C-5x0yO:
undetectable		 4n09C-5x0yO:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfo PHD FINGER PROTEIN 1

(Homo sapiens) 		PF00628
(PHD) 		4 ASN A 284
LEU A 288
SER A 282
LEU A 305
 None
 1.26A 4n09C-5xfoA:
undetectable		 4n09C-5xfoA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xi8 BETA-BARREL
ASSEMBLY-ENHANCING
PROTEASE

(Escherichia
coli) 		no annotation 4 ASN A 384
LEU A 380
LEU A 416
ASN A 400
 None
 1.31A 4n09C-5xi8A:
undetectable		 4n09C-5xi8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xrf SNAKE VENOM SERINE
PROTEASE DA-36

(Deinagkistrodon
acutus) 		no annotation 4 ASN A 169
LEU A 171
SER A 142
LEU A 190
 None
 1.22A 4n09C-5xrfA:
undetectable		 4n09C-5xrfA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 ASN A1198
SER A 584
LEU A 598
ASN A 602
 None
 1.28A 4n09C-5xsyA:
undetectable		 4n09C-5xsyA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyb -

(-) 		no annotation 4 ASN A 245
LEU A 241
LEU A 210
ASN A 208
 None
 1.27A 4n09C-5xybA:
undetectable		 4n09C-5xybA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyk PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		no annotation 4 LEU E 342
SER E 340
LEU E 243
ASN E  91
 None
MN  E 402 (-1.6A)
None
None
 0.98A 4n09C-5xykE:
undetectable		 4n09C-5xykE:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 ASN A 531
LEU A 533
SER A 553
LEU A 550
 None
 1.18A 4n09C-5y3jA:
undetectable		 4n09C-5y3jA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cjb CYSTATHIONINE
BETA-LYASE

(Legionella
pneumophila) 		no annotation 4 ASN A 202
SER A 196
LEU A 329
ASN A 149
 None
LLP  A 199 ( 2.7A)
LLP  A 199 (-4.3A)
FMT  A 401 (-3.2A)
 1.12A 4n09C-6cjbA:
undetectable		 4n09C-6cjbA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN

(Salmonella
enterica) 		no annotation 4 LEU A 329
SER A 327
LEU A 230
ASN A  78
 MPD  A 507 ( 4.7A)
MG  A 503 ( 2.2A)
MPD  A 507 (-4.9A)
None
 1.07A 4n09C-6dusA:
undetectable		 4n09C-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 4 ASN A 576
LEU A 586
SER A 601
LEU A 566
 None
 1.10A 4n09C-6eojA:
undetectable		 4n09C-6eojA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f4g PROBABLE U2 SMALL
NUCLEAR
RIBONUCLEOPROTEIN A'

(Drosophila
melanogaster) 		no annotation 4 ASN A  52
LEU A  54
LEU A  95
ASN A 123
 None
 1.12A 4n09C-6f4gA:
undetectable		 4n09C-6f4gA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARC

(Acetobacterium
woodii) 		no annotation 4 ASN C  90
LEU C  86
SER C  88
LEU C  41
 None
 1.06A 4n09C-6fahC:
undetectable		 4n09C-6fahC:
12.46