SIMILAR PATTERNS OF AMINO ACIDS FOR 4N09_B_ADNB401_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1csj | HEPATITIS C VIRUSRNA POLYMERASE(NS5B) (Hepacivirus C) |
PF00998(RdRP_3) | 4 | LEU A 419SER A 478LEU A 497ASN A 369 | None | 1.16A | 4n09B-1csjA:undetectable | 4n09B-1csjA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dc1 | BSOBI RESTRICTIONENDONUCLEASE (Geobacillusstearothermophilus) |
PF09194(Endonuc-BsobI) | 4 | LEU A 114SER A 76LEU A 49ASN A 96 | None | 1.13A | 4n09B-1dc1A:undetectable | 4n09B-1dc1A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gqp | DOC1/APC10 (Saccharomycescerevisiae) |
PF03256(ANAPC10) | 4 | LEU A 156SER A 126LEU A 234LEU A 247 | None | 1.27A | 4n09B-1gqpA:undetectable | 4n09B-1gqpA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkk | CHITOTRIOSIDASE-1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | LEU A 127SER A 122LEU A 162LEU A 94 | None | 1.22A | 4n09B-1hkkA:undetectable | 4n09B-1hkkA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ihm | CAPSID PROTEIN (Norwalk virus) |
PF00915(Calici_coat)PF08435(Calici_coat_C) | 4 | LEU A1418SER A1262LEU A1436ASN A1259 | None | 1.23A | 4n09B-1ihmA:undetectable | 4n09B-1ihmA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl5 | OUTER PROTEIN YOPM (Yersinia pestis) |
PF12468(TTSSLRR) | 4 | LEU A1109SER A1115LEU A1093LEU A1106 | None | 1.19A | 4n09B-1jl5A:undetectable | 4n09B-1jl5A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl5 | OUTER PROTEIN YOPM (Yersinia pestis) |
PF12468(TTSSLRR) | 4 | LEU A1136SER A1139LEU A1117LEU A1126 | None | 1.24A | 4n09B-1jl5A:undetectable | 4n09B-1jl5A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl5 | OUTER PROTEIN YOPM (Yersinia pestis) |
PF12468(TTSSLRR) | 4 | LEU A1213SER A1219LEU A1197LEU A1210 | None | 1.27A | 4n09B-1jl5A:undetectable | 4n09B-1jl5A:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1b | B-CELL LYMPHOMA3-ENCODED PROTEIN (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2) | 4 | LEU A 305SER A 307LEU A 316LEU A 350 | None | 1.18A | 4n09B-1k1bA:undetectable | 4n09B-1k1bA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kvk | MEVALONATE KINASE (Rattusnorvegicus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 4 | LEU A 35SER A 145LEU A 234ASN A 55 | NoneATP A 535 (-2.9A)NoneATP A 535 (-4.0A) | 1.02A | 4n09B-1kvkA:undetectable | 4n09B-1kvkA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lk3 | 9D7 HEAVY CHAIN (Rattusnorvegicus) |
PF07654(C1-set)PF07686(V-set) | 4 | LEU H 20SER H 95LEU H 114LEU H 83 | None | 1.28A | 4n09B-1lk3H:undetectable | 4n09B-1lk3H:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pdz | ENOLASE (Homarusgammarus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 144SER A 176LEU A 412LEU A 418 | None | 1.25A | 4n09B-1pdzA:undetectable | 4n09B-1pdzA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgj | CITRATE LYASE, BETASUBUNIT (Deinococcusradiodurans) |
PF03328(HpcH_HpaI) | 4 | LEU A 190SER A 10LEU A 7LEU A 125 | None | 0.93A | 4n09B-1sgjA:2.5 | 4n09B-1sgjA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wb0 | CHITOTRIOSIDASE 1 (Homo sapiens) |
PF00704(Glyco_hydro_18) | 4 | LEU A 127SER A 122LEU A 162LEU A 94 | None | 1.23A | 4n09B-1wb0A:2.4 | 4n09B-1wb0A:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zkl | HIGH-AFFINITYCAMP-SPECIFIC3',5'-CYCLICPHOSPHODIESTERASE 7A (Homo sapiens) |
PF00233(PDEase_I) | 4 | LEU A 198SER A 172LEU A 177LEU A 194 | None | 1.19A | 4n09B-1zklA:undetectable | 4n09B-1zklA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a7n | L(+)-MANDELATEDEHYDROGENASE (Pseudomonasputida;Spinaciaoleracea) |
PF01070(FMN_dh) | 4 | LEU A 306LEU A 311LEU A 329ASN A 83 | None | 1.28A | 4n09B-2a7nA:2.3 | 4n09B-2a7nA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b7h | HEMOGLOBIN ALPHACHAIN (Cerdocyon thous) |
PF00042(Globin) | 4 | LEU A 76SER A 133LEU A 66LEU A 2 | NoneHEM A 200 ( 4.8A)HEM A 200 ( 4.6A)None | 0.91A | 4n09B-2b7hA:undetectable | 4n09B-2b7hA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eig | LECTIN (Lotustetragonolobus) |
PF00139(Lectin_legB) | 4 | LEU A 192SER A 167LEU A 227LEU A 86 | None | 1.25A | 4n09B-2eigA:undetectable | 4n09B-2eigA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2elc | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE (Thermusthermophilus) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | LEU A 89LEU A 285LEU A 270ASN A 228 | None | 0.92A | 4n09B-2elcA:6.1 | 4n09B-2elcA:24.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pqq | PUTATIVETRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
PF00027(cNMP_binding) | 4 | LEU A 101SER A 27LEU A 47LEU A 37 | None | 1.13A | 4n09B-2pqqA:undetectable | 4n09B-2pqqA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyf | T-CELL RECEPTOR,BETA CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | LEU B 108SER B 106LEU B 74LEU B 11 | None | 1.25A | 4n09B-2pyfB:undetectable | 4n09B-2pyfB:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rt5 | MSX2-INTERACTINGPROTEIN (Homo sapiens) |
PF07744(SPOC) | 4 | LEU A3642SER A3637LEU A3647LEU A3575 | None | 1.25A | 4n09B-2rt5A:undetectable | 4n09B-2rt5A:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w61 | GLYCOLIPID-ANCHOREDSURFACE PROTEIN 2 (Saccharomycescerevisiae) |
PF03198(Glyco_hydro_72)PF07983(X8) | 4 | LEU A 418SER A 416LEU A 468ASN A 144 | None | 1.04A | 4n09B-2w61A:2.9 | 4n09B-2w61A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x05 | EXO-BETA-D-GLUCOSAMINIDASE (Amycolatopsisorientalis) |
PF00703(Glyco_hydro_2)PF02837(Glyco_hydro_2_N) | 4 | LEU A 823SER A 859LEU A 868ASN A 890 | None | 1.27A | 4n09B-2x05A:undetectable | 4n09B-2x05A:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z80 | TOLL-LIKE RECEPTOR2, VARIABLELYMPHOCYTE RECEPTORB (Eptatretusburgeri;Homo sapiens) |
PF11921(DUF3439)PF13855(LRR_8) | 4 | LEU A 43SER A 60LEU A 28ASN A 110 | None | 0.98A | 4n09B-2z80A:undetectable | 4n09B-2z80A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zet | MELANOPHILIN (Mus musculus) |
PF02318(FYVE_2) | 4 | LEU C 59SER C 54LEU C 86LEU C 68 | None | 1.11A | 4n09B-2zetC:undetectable | 4n09B-2zetC:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e4b | ALGK (Pseudomonasfluorescens) |
no annotation | 4 | LEU A 223SER A 218LEU A 240LEU A 199 | None | 1.20A | 4n09B-3e4bA:undetectable | 4n09B-3e4bA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebb | PHOSPHOLIPASEA2-ACTIVATINGPROTEIN (Homo sapiens) |
PF08324(PUL) | 4 | LEU A 555LEU A 614LEU A 576ASN A 655 | None | 1.00A | 4n09B-3ebbA:undetectable | 4n09B-3ebbA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efb | PROBABLE SOR-OPERONREGULATOR (Shigellaflexneri) |
PF04198(Sugar-bind) | 4 | LEU A 263SER A 258LEU A 15LEU A 253 | None | 1.24A | 4n09B-3efbA:4.1 | 4n09B-3efbA:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3evz | METHYLTRANSFERASE (Pyrococcusfuriosus) |
PF05175(MTS) | 4 | LEU A 202SER A 239LEU A 211LEU A 187 | None | 1.25A | 4n09B-3evzA:5.4 | 4n09B-3evzA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7k | 3-METHYLITACONATEISOMERASE (Eubacteriumbarkeri) |
PF04303(PrpF) | 4 | LEU A 63SER A 61LEU A 39LEU A 22 | None | 1.22A | 4n09B-3g7kA:undetectable | 4n09B-3g7kA:24.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdc | MULTICOPPER OXIDASE (Arthrobactersp. FB24) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | SER A 195LEU A 224LEU A 220ASN A 191 | None | 1.18A | 4n09B-3gdcA:undetectable | 4n09B-3gdcA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3htx | HEN1 (Arabidopsisthaliana) |
PF13847(Methyltransf_31) | 4 | SER A 486LEU A 387LEU A 373ASN A 479 | NoneNoneNone U B 9 ( 4.2A) | 1.20A | 4n09B-3htxA:4.2 | 4n09B-3htxA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3huu | TRANSCRIPTIONREGULATOR LIKEPROTEIN (Staphylococcushaemolyticus) |
PF13377(Peripla_BP_3) | 4 | LEU A 88LEU A 258LEU A 25ASN A 124 | None | 1.20A | 4n09B-3huuA:2.7 | 4n09B-3huuA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3icc | PUTATIVE3-OXOACYL-(ACYLCARRIER PROTEIN)REDUCTASE (Bacillusanthracis) |
PF13561(adh_short_C2) | 4 | LEU A 76LEU A 92LEU A 80ASN A 94 | LEU A 76 ( 0.6A)LEU A 92 ( 0.6A)LEU A 80 ( 0.5A)ASN A 94 ( 0.6A) | 0.95A | 4n09B-3iccA:7.8 | 4n09B-3iccA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ivu | HOMOCITRATESYNTHASE,MITOCHONDRIAL (Schizosaccharomycespombe) |
PF00682(HMGL-like) | 4 | LEU A 290LEU A 252LEU A 65ASN A 306 | None | 0.92A | 4n09B-3ivuA:2.6 | 4n09B-3ivuA:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | U2 SMALL NUCLEARRIBONUCLEOPROTEIN A' (Schizosaccharomycespombe) |
PF01423(LSM) | 4 | LEU j 92SER j 118LEU j 69LEU j 56 | None | 1.06A | 4n09B-3jb9j:undetectable | 4n09B-3jb9j:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jcu | OXYGEN-EVOLVINGENHANCER PROTEIN 2,CHLOROPLASTIC (Spinaciaoleracea) |
PF01789(PsbP) | 4 | LEU P 88SER P 110LEU P 132LEU P 81 | None | 1.17A | 4n09B-3jcuP:undetectable | 4n09B-3jcuP:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k33 | DEATH ON CURINGPROTEIN (Escherichiavirus P1) |
PF02661(Fic) | 4 | LEU A 81SER A 79LEU A 118ASN A 16 | None | 1.15A | 4n09B-3k33A:undetectable | 4n09B-3k33A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kl9 | GLUTAMYLAMINOPEPTIDASE (Streptococcuspneumoniae) |
PF05343(Peptidase_M42) | 4 | LEU A 207SER A 209LEU A 62LEU A 192 | None | 1.26A | 4n09B-3kl9A:2.2 | 4n09B-3kl9A:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lfk | MARR LIKE PROTEIN,TVG0766549 (Thermoplasmavolcanium) |
no annotation | 4 | LEU A 89SER A 91LEU A 77LEU A 39 | None | 1.15A | 4n09B-3lfkA:undetectable | 4n09B-3lfkA:17.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3loo | ANOPHELES GAMBIAEADENOSINE KINASE (Anophelesgambiae) |
PF00294(PfkB) | 4 | LEU A 16SER A 65LEU A 133LEU A 137 | B4P A 349 (-4.7A) CL A 351 ( 4.6A)B4P A 349 (-4.5A)None | 0.45A | 4n09B-3looA:48.0 | 4n09B-3looA:36.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mn8 | LP15968P (Drosophilamelanogaster) |
PF00246(Peptidase_M14)PF13620(CarboxypepD_reg) | 4 | LEU A 251SER A 213LEU A 332LEU A 377 | None | 1.13A | 4n09B-3mn8A:2.4 | 4n09B-3mn8A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ndp | ADENYLATE KINASEISOENZYME 4 (Homo sapiens) |
PF00406(ADK)PF05191(ADK_lid) | 4 | LEU A 77LEU A 72LEU A 100ASN A 43 | None | 1.14A | 4n09B-3ndpA:4.1 | 4n09B-3ndpA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nyo | G PROTEIN-COUPLEDRECEPTOR KINASE 6 (Homo sapiens) |
PF00069(Pkinase)PF00615(RGS) | 4 | LEU A 171LEU A 66LEU A 49ASN A 525 | None | 1.07A | 4n09B-3nyoA:undetectable | 4n09B-3nyoA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oja | LEUCINE-RICH IMMUNEMOLECULE 1 (Anophelesgambiae) |
PF00560(LRR_1) | 4 | LEU A 98LEU A 109LEU A 76ASN A 131 | None | 1.19A | 4n09B-3ojaA:undetectable | 4n09B-3ojaA:22.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 4 | LEU A 15SER A 64LEU A 134LEU A 138 | AP5 A 346 (-4.4A) NA A 347 (-4.8A)AP5 A 346 ( 4.4A)None | 0.22A | 4n09B-3otxA:58.2 | 4n09B-3otxA:99.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgh | RNA-DIRECTED RNAPOLYMERASE (Hepacivirus C) |
PF00998(RdRP_3) | 4 | LEU A 419SER A 478LEU A 497ASN A 369 | None | 1.17A | 4n09B-3qghA:undetectable | 4n09B-3qghA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rlf | MALTOSE TRANSPORTSYSTEM PERMEASEPROTEIN MALG (Escherichiacoli) |
PF00528(BPD_transp_1) | 4 | LEU G 236SER G 234LEU G 137LEU G 156 | None | 1.07A | 4n09B-3rlfG:undetectable | 4n09B-3rlfG:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s30 | HYPOTHETICALGLYCOSIDE HYDROLASE (Bacteroidesvulgatus) |
PF13201(PCMD) | 4 | LEU A 150SER A 163LEU A 160LEU A 195 | None | 1.24A | 4n09B-3s30A:undetectable | 4n09B-3s30A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5k | FALCILYSIN (Plasmodiumfalciparum) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C)PF08367(M16C_assoc) | 4 | LEU A1015SER A1060LEU A1022LEU A1156 | None | 1.18A | 4n09B-3s5kA:undetectable | 4n09B-3s5kA:13.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a5q | CHI1 (Yersiniaentomophaga) |
PF00704(Glyco_hydro_18) | 4 | LEU A 113LEU A 71LEU A 102ASN A 321 | None | 1.26A | 4n09B-4a5qA:undetectable | 4n09B-4a5qA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d3c | SFN68 FAB (Oryctolaguscuniculus) |
PF07654(C1-set)PF07686(V-set) | 4 | LEU L 2SER L 28LEU L 32LEU L 4 | None | 1.14A | 4n09B-4d3cL:undetectable | 4n09B-4d3cL:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ewj | ENOLASE 2 (Streptococcussuis) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 142SER A 174LEU A 412LEU A 418 | None | 1.28A | 4n09B-4ewjA:undetectable | 4n09B-4ewjA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifq | NUCLEOPORIN NUP192 (Saccharomycescerevisiae) |
PF11894(Nup192) | 4 | LEU A 145LEU A 193LEU A 216ASN A 36 | None | 0.96A | 4n09B-4ifqA:undetectable | 4n09B-4ifqA:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jcl | CYCLOMALTODEXTRINGLUCANOTRANSFERASE (Paenibacillusmacerans) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG) | 4 | LEU A 614SER A 642LEU A 649ASN A 581 | None | 1.05A | 4n09B-4jclA:2.3 | 4n09B-4jclA:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k37 | ANAEROBICSULFATASE-MATURATINGENZYME (Clostridiumperfringens) |
PF04055(Radical_SAM)PF13186(SPASM)PF13353(Fer4_12) | 4 | LEU A 112SER A 107LEU A 152LEU A 97 | None | 1.02A | 4n09B-4k37A:2.8 | 4n09B-4k37A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lkr | PURINE NUCLEOSIDEPHOSPHORYLASEDEOD-TYPE (Shewanellaoneidensis) |
PF01048(PNP_UDP_1) | 4 | LEU A 197SER A 132LEU A 105ASN A 234 | None | 1.28A | 4n09B-4lkrA:undetectable | 4n09B-4lkrA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m7e | BRASSINOSTEROIDINSENSITIVE1-ASSOCIATEDRECEPTOR KINASE 1 (Arabidopsisthaliana) |
no annotation | 4 | LEU D 139SER D 120LEU D 94LEU D 136 | None | 1.26A | 4n09B-4m7eD:undetectable | 4n09B-4m7eD:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mdr | AP-4 COMPLEX SUBUNITMU-1 (Homo sapiens) |
PF00928(Adap_comp_sub) | 4 | LEU A 315SER A 301LEU A 377LEU A 334 | None | 1.09A | 4n09B-4mdrA:undetectable | 4n09B-4mdrA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mhp | GLUTAMINYL CYCLASE,PUTATIVE (Ixodesscapularis) |
PF04389(Peptidase_M28) | 4 | LEU A 163SER A 158LEU A 88LEU A 175 | None | 1.08A | 4n09B-4mhpA:undetectable | 4n09B-4mhpA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mt1 | DRUG EFFLUX PROTEIN (Neisseriagonorrhoeae) |
PF00873(ACR_tran) | 4 | SER A 721LEU A 718LEU A 692ASN A 618 | None | 1.08A | 4n09B-4mt1A:undetectable | 4n09B-4mt1A:16.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oan | TRAP DICARBOXYLATETRANSPORTER DCTPSUBUNIT (Rhodopseudomonaspalustris) |
PF03480(DctP) | 4 | LEU A 97LEU A 100LEU A 84ASN A 112 | None | 0.99A | 4n09B-4oanA:undetectable | 4n09B-4oanA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ow2 | YOP EFFECTOR YOPM (Yersiniaenterocolitica) |
PF12468(TTSSLRR) | 4 | LEU A 325SER A 341LEU A 308ASN A 383 | None | 1.13A | 4n09B-4ow2A:undetectable | 4n09B-4ow2A:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ow2 | YOP EFFECTOR YOPM (Yersiniaenterocolitica) |
PF12468(TTSSLRR) | 4 | LEU A 385SER A 401LEU A 368ASN A 443 | None | 1.14A | 4n09B-4ow2A:undetectable | 4n09B-4ow2A:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psp | ALPHA-FUCOSIDASEGH29 (Fusariumgraminearum) |
PF01120(Alpha_L_fucos)PF16757(Fucosidase_C) | 4 | LEU A 198SER A 190LEU A 195LEU A 206 | None | 1.02A | 4n09B-4pspA:2.6 | 4n09B-4pspA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdn | FLAGELLAR PROTEINFLGJ [PEPTIDOGLYCANHYDROLASE] (Thermotogamaritima) |
PF01832(Glucosaminidase) | 4 | LEU A 27SER A 12LEU A 46LEU A 89 | None | 1.06A | 4n09B-4qdnA:undetectable | 4n09B-4qdnA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfv | ANK-N5C-281 (syntheticconstruct) |
PF00023(Ank)PF12796(Ank_2)PF13637(Ank_4) | 4 | LEU A 174SER A 176LEU A 185LEU A 222 | None | 1.24A | 4n09B-4qfvA:undetectable | 4n09B-4qfvA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tlv | ADP-RIBOSYLATINGTOXIN CARDS (Mycoplasmapneumoniae) |
PF02917(Pertussis_S1) | 4 | LEU A 38SER A 225LEU A 123LEU A 260 | None | 1.28A | 4n09B-4tlvA:undetectable | 4n09B-4tlvA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8j | PESTICIDAL CRYSTALPROTEIN CRY1AC (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 4 | LEU A 656SER A 669LEU A 662LEU A 618 | None | 1.11A | 4n09B-4w8jA:undetectable | 4n09B-4w8jA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yac | CALPHA-DEHYDROGENASE (Sphingobium sp.SYK-6) |
PF00106(adh_short) | 4 | LEU A 185SER A 144LEU A 250LEU A 234 | None | 0.85A | 4n09B-4yacA:7.5 | 4n09B-4yacA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z17 | ENOLASE (Chloroflexusaurantiacus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 143SER A 175LEU A 406LEU A 412 | None | 1.22A | 4n09B-4z17A:undetectable | 4n09B-4z17A:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z61 | PHYTOSULFOKINERECEPTOR 1 (Daucus carota) |
PF00560(LRR_1)PF13855(LRR_8) | 4 | LEU A 451SER A 446LEU A 469LEU A 430 | None | 1.24A | 4n09B-4z61A:undetectable | 4n09B-4z61A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zke | SUPERKILLER PROTEIN7 (Saccharomycescerevisiae) |
PF00009(GTP_EFTU) | 4 | LEU A 687SER A 697LEU A 704LEU A 674 | LEU A 687 ( 0.6A)SER A 697 ( 0.0A)LEU A 704 ( 0.6A)LEU A 674 ( 0.6A) | 1.09A | 4n09B-4zkeA:4.1 | 4n09B-4zkeA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoq | INTRACELLULAR SERINEPROTEASE (Bacilluslicheniformis) |
PF00082(Peptidase_S8) | 4 | LEU I 345SER I 370LEU I 377LEU I 330 | None | 1.01A | 4n09B-4zoqI:5.5 | 4n09B-4zoqI:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5by7 | 3-OXOACYL-ACPSYNTHASE III (Verrucosisporamaris) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | LEU A 167SER A -10LEU A 127LEU A 111 | None | 1.14A | 4n09B-5by7A:undetectable | 4n09B-5by7A:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5df0 | AC-CHIA (Autographacalifornicamultiplenucleopolyhedrovirus) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 4 | LEU A 171SER A 175LEU A 538ASN A 542 | None | 1.04A | 4n09B-5df0A:4.0 | 4n09B-5df0A:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dfa | BETA-GALACTOSIDASE (Geobacillusstearothermophilus) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | LEU A 359SER A 283LEU A 17ASN A 158 | NoneNoneNoneGOL A 703 ( 4.0A) | 1.16A | 4n09B-5dfaA:3.8 | 4n09B-5dfaA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ezr | CGMP-DEPENDENTPROTEIN KINASE,PUTATIVE (Plasmodiumvivax) |
PF00027(cNMP_binding)PF00069(Pkinase) | 4 | LEU A 658LEU A 648LEU A 715ASN A 589 | None | 0.88A | 4n09B-5ezrA:undetectable | 4n09B-5ezrA:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hb1 | NUCLEOPORIN NUP170 (Chaetomiumthermophilum) |
PF03177(Nucleoporin_C) | 4 | LEU A1244SER A1246LEU A1291ASN A1252 | None | 1.23A | 4n09B-5hb1A:undetectable | 4n09B-5hb1A:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hsg | PUTATIVE ABCTRANSPORTER,NUCLEOTIDEBINDING/ATPASEPROTEIN (Klebsiellapneumoniae) |
PF13407(Peripla_BP_4) | 4 | LEU A 315SER A 311LEU A 252LEU A 49 | None | 1.04A | 4n09B-5hsgA:5.6 | 4n09B-5hsgA:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT BETA (Methylobacillusflagellatus) |
PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | LEU C 73SER C 33LEU C 29LEU C 43 | None | 1.24A | 4n09B-5ks8C:2.5 | 4n09B-5ks8C:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldt | MOMP PORIN (Campylobacterjejuni) |
PF05538(Campylo_MOMP) | 4 | LEU A 310SER A 308LEU A 297ASN A 32 | None | 1.15A | 4n09B-5ldtA:undetectable | 4n09B-5ldtA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lt9 | METHYL-ACCEPTINGCHEMOTAXIS PROTEINPCTB (Pseudomonasaeruginosa) |
PF02743(dCache_1) | 4 | LEU A 46SER A 261LEU A 42ASN A 184 | None | 0.98A | 4n09B-5lt9A:undetectable | 4n09B-5lt9A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2s | SOLUBLE CYTOCHROMEB562,ADENOSINERECEPTOR A1 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 4 | LEU A1156SER A1386LEU A1195LEU A1203 | None | 1.15A | 4n09B-5n2sA:undetectable | 4n09B-5n2sA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opq | 3,6-ANHYDRO-D-GALACTOSIDASE (Zobelliagalactanivorans) |
no annotation | 4 | LEU A 418SER A 420LEU A 512LEU A 333 | None | 0.80A | 4n09B-5opqA:undetectable | 4n09B-5opqA:12.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqr | CONDENSIN COMPLEXSUBUNIT 3 (Schizosaccharomycespombe) |
no annotation | 4 | LEU A 250LEU A 280LEU A 265ASN A 236 | None | 1.17A | 4n09B-5oqrA:undetectable | 4n09B-5oqrA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oqr | CONDENSIN COMPLEXSUBUNIT 3 (Schizosaccharomycespombe) |
no annotation | 4 | LEU A 385SER A 387LEU A 408LEU A 422 | None | 0.94A | 4n09B-5oqrA:undetectable | 4n09B-5oqrA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tc1 | MATURATION PROTEIN (Escherichiavirus MS2) |
PF03863(Phage_mat-A) | 4 | LEU M 65SER M 100LEU M 104LEU M 111 | None | 1.17A | 4n09B-5tc1M:undetectable | 4n09B-5tc1M:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tpk | PROTOCADHERIN-15 (Mus musculus) |
no annotation | 4 | LEU A 782LEU A 766LEU A 700ASN A 737 | None | 1.25A | 4n09B-5tpkA:undetectable | 4n09B-5tpkA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u30 | CRISPR-ASSOCIATEDENDONUCLEASE C2C1 (Alicyclobacillusacidoterrestris) |
no annotation | 4 | LEU A 847SER A 568LEU A 844LEU A 879 | None | 1.23A | 4n09B-5u30A:undetectable | 4n09B-5u30A:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ul4 | OXSB PROTEIN (Bacillusmegaterium) |
PF02310(B12-binding) | 4 | LEU A 541SER A 594LEU A 486LEU A 640 | EDO A 814 (-4.8A)NoneNoneNone | 1.28A | 4n09B-5ul4A:5.9 | 4n09B-5ul4A:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v7i | SERINEHYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | LEU A 164SER A 226LEU A 166LEU A 197 | NoneLLP A 280 (-3.4A)8Z1 A 601 (-4.7A)None | 1.15A | 4n09B-5v7iA:4.6 | 4n09B-5v7iA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x41 | COBALT ABCTRANSPORTERATP-BINDING PROTEIN (Rhodobactercapsulatus) |
PF00005(ABC_tran) | 4 | LEU A 37SER A 196LEU A 202LEU A 239 | None | 0.86A | 4n09B-5x41A:undetectable | 4n09B-5x41A:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xox | TRNA(HIS)GUANYLYLTRANSFERASE (Saccharomycescerevisiae) |
PF04446(Thg1)PF14413(Thg1C) | 4 | SER A 107LEU A 112LEU A 122ASN A 60 | None | 1.21A | 4n09B-5xoxA:undetectable | 4n09B-5xoxA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xr2 | PROTEIN/NUCLEIC ACIDDEGLYCASE HCHA (Staphylococcusaureus) |
no annotation | 4 | LEU A 238SER A 219LEU A 235ASN A 252 | None | 1.18A | 4n09B-5xr2A:4.7 | 4n09B-5xr2A:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c54 | NUCLEOPROTEIN (Zaireebolavirus) |
no annotation | 4 | LEU A 74SER A 72LEU A 209LEU A 203 | None | 0.98A | 4n09B-6c54A:undetectable | 4n09B-6c54A:14.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT BMONOVALENT CATION/H+ANTIPORTER SUBUNIT FMONOVALENT CATION/H+ANTIPORTER SUBUNIT G (Pyrococcusfuriosus) |
no annotation | 4 | LEU B 66SER B 68LEU C 83LEU F 16 | None | 1.05A | 4n09B-6cfwB:undetectable | 4n09B-6cfwB:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ez8 | HUNTINGTIN (Homo sapiens) |
no annotation | 4 | LEU A1267SER A1271LEU A1141LEU A1293 | None | 1.23A | 4n09B-6ez8A:undetectable | 4n09B-6ez8A:8.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN4 (Mus musculus) |
no annotation | 4 | LEU M 106SER M 101LEU M 73LEU M 235 | None3PE M 505 ( 3.8A)NoneNone | 0.86A | 4n09B-6g2jM:undetectable | 4n09B-6g2jM:11.90 |