SIMILAR PATTERNS OF AMINO ACIDS FOR 4MS4_A_2C0A501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bud | PROTEIN (ACUTOLYSINA) (Deinagkistrodonacutus) |
PF01421(Reprolysin) | 4 | SER A 115SER A 122TYR A 189ILE A 198 | None | 1.27A | 4ms4A-1budA:4.0 | 4ms4A-1budA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8m | HUMAN RHINOVIRUS 16COAT PROTEIN (Rhinovirus A) |
PF00073(Rhv) | 4 | TRP 2 79SER 2 167HIS 2 130ILE 2 224 | None | 1.19A | 4ms4A-1c8m2:undetectable | 4ms4A-1c8m2:18.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c9e | PROTOHEME FERROLYASE (Bacillussubtilis) |
PF00762(Ferrochelatase) | 4 | SER A 121HIS A 183ILE A 29GLU A 264 | MP1 A 800 (-3.4A)MP1 A 800 (-3.6A)MP1 A 800 (-4.5A)MP1 A 800 (-4.3A) | 0.97A | 4ms4A-1c9eA:3.9 | 4ms4A-1c9eA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnn | CELL DIVISIONCONTROL PROTEIN 6 (Pyrobaculumaerophilum) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | SER A 269SER A 249ILE A 218GLU A 264 | None | 1.35A | 4ms4A-1fnnA:undetectable | 4ms4A-1fnnA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h54 | MALTOSEPHOSPHORYLASE (Lactobacillusbrevis) |
PF03632(Glyco_hydro_65m)PF03633(Glyco_hydro_65C)PF03636(Glyco_hydro_65N) | 4 | HIS A 555TYR A 619ILE A 563GLU A 489 | NoneNoneNone K A1754 (-2.6A) | 1.19A | 4ms4A-1h54A:undetectable | 4ms4A-1h54A:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfh | FACTOR H, 15TH AND16TH C-MODULE PAIR (Homo sapiens) |
PF00084(Sushi) | 4 | HIS A 13TYR A 34ILE A 42GLU A 12 | None | 1.36A | 4ms4A-1hfhA:undetectable | 4ms4A-1hfhA:14.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hlk | BETA-LACTAMASE, TYPEII (Bacteroidesfragilis) |
no annotation | 4 | SER A 42SER A 54HIS A 223ILE A 46 | NA A2001 ( 4.6A) NA A2001 ( 4.9A)113 A2002 ( 3.6A)113 A2002 (-4.1A) | 1.35A | 4ms4A-1hlkA:undetectable | 4ms4A-1hlkA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k32 | TRICORN PROTEASE (Thermoplasmaacidophilum) |
PF03572(Peptidase_S41)PF07676(PD40)PF14684(Tricorn_C1)PF14685(Tricorn_PDZ) | 4 | SER A 965TYR A 748ILE A 994GLU A1023 | None | 1.14A | 4ms4A-1k32A:3.4 | 4ms4A-1k32A:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ko0 | DIAMINOPIMELATEDECARBOXYLASE (Escherichiacoli) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | SER A 134SER A 113ILE A 104GLU A 110 | None | 1.23A | 4ms4A-1ko0A:undetectable | 4ms4A-1ko0A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kq0 | METHIONINEAMINOPEPTIDASE 2 (Homo sapiens) |
PF00557(Peptidase_M24) | 4 | TRP A 419SER A 381ILE A 194GLU A 201 | None | 1.27A | 4ms4A-1kq0A:undetectable | 4ms4A-1kq0A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kzh | PHOSPHOFRUCTOKINASE (Borreliellaburgdorferi) |
PF00365(PFK) | 4 | SER A 256SER A 274ILE A 287GLU A 276 | None | 1.23A | 4ms4A-1kzhA:1.8 | 4ms4A-1kzhA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8k | T-CELLPROTEIN-TYROSINEPHOSPHATASE (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | SER A 202SER A 204HIS A 209ILE A 172 | None | 1.14A | 4ms4A-1l8kA:undetectable | 4ms4A-1l8kA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbw | GLYCEROL DEHYDRATASEREACTIVASE ALPHASUBUNIT (Klebsiellapneumoniae) |
PF08841(DDR) | 4 | SER A 245HIS A 100ILE A 164GLU A 352 | None | 1.35A | 4ms4A-1nbwA:undetectable | 4ms4A-1nbwA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pgj | 6-PHOSPHOGLUCONATEDEHYDROGENASE (Trypanosomabrucei) |
PF00393(6PGD)PF03446(NAD_binding_2) | 4 | SER A 431SER A 339TYR A 410ILE A 403 | None | 1.31A | 4ms4A-1pgjA:4.1 | 4ms4A-1pgjA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1a | HST2 PROTEIN (Saccharomycescerevisiae) |
PF02146(SIR2) | 4 | SER A 270HIS A 97ILE A 41GLU A 121 | OAD A1001 (-3.5A)NoneNoneNone | 1.22A | 4ms4A-1q1aA:3.5 | 4ms4A-1q1aA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qdm | PROPHYTEPSIN (Hordeum vulgare) |
PF00026(Asp)PF03489(SapB_2)PF05184(SapB_1) | 4 | SER A 40SER A 134TYR A 143GLU A 105 | None | 1.35A | 4ms4A-1qdmA:undetectable | 4ms4A-1qdmA:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rpm | RECEPTOR PROTEINTYROSINE PHOSPHATASEMU (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | SER A1084SER A 993ILE A1037GLU A1052 | None | 1.19A | 4ms4A-1rpmA:2.5 | 4ms4A-1rpmA:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wta | 5'-METHYLTHIOADENOSINE PHOSPHORYLASE (Aeropyrumpernix) |
PF01048(PNP_UDP_1) | 4 | SER A 95SER A 93TYR A 167ILE A 201 | PO4 A 400 (-2.8A)NoneNoneNone | 1.09A | 4ms4A-1wtaA:2.4 | 4ms4A-1wtaA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x7p | RRNAMETHYLTRANSFERASE (Streptomycesviridochromogenes) |
PF00588(SpoU_methylase) | 4 | SER A 176SER A 179HIS A 55GLU A 54 | None | 1.22A | 4ms4A-1x7pA:3.4 | 4ms4A-1x7pA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yt8 | THIOSULFATESULFURTRANSFERASE (Pseudomonasaeruginosa) |
PF00581(Rhodanese) | 4 | SER A 49SER A 418ILE A 487GLU A 73 | None | 1.19A | 4ms4A-1yt8A:3.0 | 4ms4A-1yt8A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z8l | GLUTAMATECARBOXYPEPTIDASE II (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 4 | SER A 483SER A 496TYR A 537GLU A 486 | NoneNoneNoneNAG A1757 (-2.7A) | 1.20A | 4ms4A-1z8lA:3.4 | 4ms4A-1z8lA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2adu | METHIONINEAMINOPEPTIDASE 2 (Homo sapiens) |
PF00557(Peptidase_M24) | 4 | TRP A 419SER A 381ILE A 194GLU A 201 | None | 1.23A | 4ms4A-2aduA:undetectable | 4ms4A-2aduA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c5u | RNA LIGASE (Escherichiavirus T4) |
PF09511(RNA_lig_T4_1) | 4 | SER A 26SER A 28TYR A 108GLU A 113 | None | 1.18A | 4ms4A-2c5uA:undetectable | 4ms4A-2c5uA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2edj | ROUNDABOUT HOMOLOG 2 (Homo sapiens) |
PF07679(I-set) | 4 | SER A 85SER A 83ILE A 10GLU A 87 | None | 1.22A | 4ms4A-2edjA:undetectable | 4ms4A-2edjA:13.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f2a | ASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT BASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT C (Staphylococcusaureus) |
PF02637(GatB_Yqey)PF02686(Glu-tRNAGln)PF02934(GatB_N) | 4 | SER B 130SER B 137TYR B 83ILE C 94 | None | 1.19A | 4ms4A-2f2aB:undetectable | 4ms4A-2f2aB:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ggs | 273AA LONGHYPOTHETICALDTDP-4-DEHYDRORHAMNOSE REDUCTASE (Sulfurisphaeratokodaii) |
PF04321(RmlD_sub_bind) | 4 | SER A 21SER A 17ILE A 35GLU A 15 | None | 1.36A | 4ms4A-2ggsA:4.6 | 4ms4A-2ggsA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsk | VITAMIN B12TRANSPORTER BTUB (Escherichiacoli) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | SER A 392SER A 415ILE A 461GLU A 413 | None | 1.27A | 4ms4A-2gskA:undetectable | 4ms4A-2gskA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h31 | MULTIFUNCTIONALPROTEIN ADE2 (Homo sapiens) |
PF00731(AIRC)PF01259(SAICAR_synt) | 4 | SER A 400SER A 179HIS A 396ILE A 64 | None | 1.29A | 4ms4A-2h31A:9.1 | 4ms4A-2h31A:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i2w | PHOSPHOHEPTOSEISOMERASE (Escherichiacoli) |
PF13580(SIS_2) | 4 | SER A 121SER A 119ILE A 128GLU A 159 | None | 1.34A | 4ms4A-2i2wA:3.9 | 4ms4A-2i2wA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2krf | TRANSCRIPTIONALREGULATORY PROTEINCOMA (Bacillussubtilis) |
PF00196(GerE) | 4 | SER A 191SER A 188ILE A 174GLU A 186 | None | 1.34A | 4ms4A-2krfA:undetectable | 4ms4A-2krfA:10.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ooq | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE T (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | SER A 945SER A 949HIS A 948ILE A 970 | None | 1.16A | 4ms4A-2ooqA:2.5 | 4ms4A-2ooqA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3g | MAP KINASE-ACTIVATEDPROTEIN KINASE 2 (Homo sapiens) |
PF00069(Pkinase) | 4 | SER X 169TYR X 194ILE X 202GLU X 165 | None | 1.36A | 4ms4A-2p3gX:undetectable | 4ms4A-2p3gX:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p6r | AFUHEL308 HELICASE (Archaeoglobusfulgidus) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | SER A 544HIS A 512ILE A 495GLU A 560 | None | 1.28A | 4ms4A-2p6rA:2.9 | 4ms4A-2p6rA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po2 | PROBABLE EXOSOMECOMPLEX EXONUCLEASE2 (Pyrococcusabyssi) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | SER B 232SER B 117ILE B 158GLU B 227 | NoneNoneNoneMPD B 280 (-4.1A) | 1.30A | 4ms4A-2po2B:undetectable | 4ms4A-2po2B:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ps2 | PUTATIVE MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Aspergillusoryzae) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | SER A 53SER A 271ILE A 61GLU A 102 | None | 1.06A | 4ms4A-2ps2A:3.2 | 4ms4A-2ps2A:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qtk | PROBABLE PORIN (Pseudomonasaeruginosa) |
PF03573(OprD) | 4 | TRP A 275SER A 170TYR A 206ILE A 244 | None | 1.29A | 4ms4A-2qtkA:undetectable | 4ms4A-2qtkA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v55 | RHO-ASSOCIATEDPROTEIN KINASE 1 (Homo sapiens) |
PF00069(Pkinase) | 4 | SER A 263SER A 242ILE A 195GLU A 258 | None | 1.32A | 4ms4A-2v55A:undetectable | 4ms4A-2v55A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xn1 | ALPHA-GALACTOSIDASE (Lactobacillusacidophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | SER A 228TYR A 570ILE A 548GLU A 206 | None | 1.11A | 4ms4A-2xn1A:undetectable | 4ms4A-2xn1A:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfn | ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK ([Ruminococcus]gnavus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | SER A 224TYR A 558ILE A 536GLU A 202 | None | 1.01A | 4ms4A-2yfnA:undetectable | 4ms4A-2yfnA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5k | TYROSINE-PROTEINPHOSPHATASENON-RECEPTOR TYPE 1 (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | SER A 201SER A 203HIS A 208ILE A 171 | None | 1.14A | 4ms4A-3a5kA:2.5 | 4ms4A-3a5kA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c75 | AMICYANINMETHYLAMINEDEHYDROGENASE HEAVYCHAINMETHYLAMINEDEHYDROGENASE LIGHTCHAIN (Paracoccusversutus) |
PF00127(Copper-bind)PF02975(Me-amine-dh_L)PF06433(Me-amine-dh_H) | 4 | HIS A 96TYR H 222ILE L 106GLU L 101 | CU A 107 (-3.3A)NoneNoneNone | 1.21A | 4ms4A-3c75A:undetectable | 4ms4A-3c75A:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dp9 | MTA/SAH NUCLEOSIDASE (Vibrio cholerae) |
PF01048(PNP_UDP_1) | 4 | SER A 197SER A 76ILE A 50GLU A 173 | BIG A 301 (-3.3A)BIG A 301 (-3.3A)BIG A 301 (-3.8A)None | 1.18A | 4ms4A-3dp9A:2.9 | 4ms4A-3dp9A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dra | GERANYLGERANYLTRANSFERASE TYPE I BETASUBUNITPROTEINFARNESYLTRANSFERASE/GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNITALPHA (Candidaalbicans) |
PF00432(Prenyltrans)PF01239(PPTA) | 4 | TRP A 296SER A 258HIS B 249ILE A 291 | None | 1.33A | 4ms4A-3draA:undetectable | 4ms4A-3draA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e59 | PYOVERDINEBIOSYNTHESIS PROTEINPVCA (Pseudomonasaeruginosa) |
PF05141(DIT1_PvcA) | 4 | TRP A 279SER A 112TYR A 131ILE A 128 | None | 1.29A | 4ms4A-3e59A:undetectable | 4ms4A-3e59A:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fbt | CHORISMATE MUTASEAND SHIKIMATE5-DEHYDROGENASEFUSION PROTEIN (Clostridiumacetobutylicum) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 4 | SER A 111HIS A 110TYR A 308ILE A 116 | None | 1.24A | 4ms4A-3fbtA:2.4 | 4ms4A-3fbtA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgt | PUTATIVEPHOSPHOLIPASE B-LIKE2 40 KDA FORM (Mus musculus) |
PF04916(Phospholip_B) | 4 | SER B 305HIS B 266TYR B 307GLU B 328 | NoneOCS B 249 ( 4.3A)None NA B 606 (-2.7A) | 1.27A | 4ms4A-3fgtB:undetectable | 4ms4A-3fgtB:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgt | PUTATIVEPHOSPHOLIPASE B-LIKE2 40 KDA FORM (Mus musculus) |
PF04916(Phospholip_B) | 4 | SER B 305HIS B 266TYR B 307ILE B 536 | NoneOCS B 249 ( 4.3A)NoneNone | 1.35A | 4ms4A-3fgtB:undetectable | 4ms4A-3fgtB:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fgw | PUTATIVEPHOSPHOLIPASE B-LIKE2 (Mus musculus) |
PF04916(Phospholip_B) | 4 | SER A 305HIS A 266TYR A 307GLU A 328 | NoneNoneNone NA A 610 (-3.1A) | 1.28A | 4ms4A-3fgwA:undetectable | 4ms4A-3fgwA:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k5j | SUPPRESSOR OF FUSEDFAMILY PROTEIN (Neisseriagonorrhoeae) |
PF05076(SUFU) | 4 | SER A 70HIS A 77ILE A 172GLU A 76 | None | 0.99A | 4ms4A-3k5jA:undetectable | 4ms4A-3k5jA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n5f | N-CARBAMOYL-L-AMINOACID HYDROLASE (Geobacillusstearothermophilus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | SER A 78HIS A 79ILE A 190GLU A 125 | CO A 410 ( 4.7A) CO A 410 (-3.2A)None CO A 410 ( 4.7A) | 1.15A | 4ms4A-3n5fA:2.0 | 4ms4A-3n5fA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n6n | RNA-DEPENDENT RNAPOLYMERASE (Enterovirus A) |
PF00680(RdRP_1) | 4 | SER A 295SER A 292TYR A 327GLU A 108 | None | 1.35A | 4ms4A-3n6nA:undetectable | 4ms4A-3n6nA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nkh | INTEGRASE (Staphylococcusaureus) |
PF00589(Phage_integrase) | 4 | SER A 197SER A -2HIS A 201GLU A 204 | None | 1.06A | 4ms4A-3nkhA:undetectable | 4ms4A-3nkhA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s1s | RESTRICTIONENDONUCLEASE BPUSI (Bacilluspumilus) |
PF02384(N6_Mtase)PF15516(BpuSI_N) | 4 | SER A 762HIS A 727ILE A 819GLU A 745 | None | 1.23A | 4ms4A-3s1sA:4.3 | 4ms4A-3s1sA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t66 | NICKEL ABCTRANSPORTER(NICKEL-BINDINGPROTEIN) (Bacillushalodurans) |
PF00496(SBP_bac_5) | 4 | SER A 385HIS A 242TYR A 337GLU A 342 | None | 1.27A | 4ms4A-3t66A:2.1 | 4ms4A-3t66A:23.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thz | DNA MISMATCH REPAIRPROTEIN MSH2 (Homo sapiens) |
PF00488(MutS_V)PF01624(MutS_I)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | SER A 738SER A 734ILE A 216GLU A 731 | None | 1.25A | 4ms4A-3thzA:undetectable | 4ms4A-3thzA:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tia | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | SER A 228SER A 279TYR A 423TRP A 352 | None | 1.14A | 4ms4A-3tiaA:undetectable | 4ms4A-3tiaA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tny | YFIY (ABC TRANSPORTSYSTEMSUBSTRATE-BINDINGPROTEIN) (Bacillus cereus) |
PF01497(Peripla_BP_2) | 4 | HIS A 92TYR A 122ILE A 24GLU A 69 | None | 1.04A | 4ms4A-3tnyA:3.1 | 4ms4A-3tnyA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tny | YFIY (ABC TRANSPORTSYSTEMSUBSTRATE-BINDINGPROTEIN) (Bacillus cereus) |
PF01497(Peripla_BP_2) | 4 | SER A 108HIS A 92ILE A 24GLU A 69 | None | 1.22A | 4ms4A-3tnyA:3.1 | 4ms4A-3tnyA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v8u | TRANSFERRINBINDING-PROTEIN B (Neisseriameningitidis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | SER A 137SER A 344TYR A 103GLU A 327 | None | 1.20A | 4ms4A-3v8uA:undetectable | 4ms4A-3v8uA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9f | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSEREGULATOR, HYBRID(ONE-COMPONENTSYSTEM) (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 4 | SER A 34TYR A 69ILE A 80GLU A 84 | None | 0.87A | 4ms4A-3v9fA:undetectable | 4ms4A-3v9fA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ve2 | TRANSFERRIN-BINDINGPROTEIN 2 (Neisseriameningitidis) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | SER A 137SER A 343TYR A 104GLU A 326 | None | 1.16A | 4ms4A-3ve2A:undetectable | 4ms4A-3ve2A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btg | MAJOR INNER PROTEINP1 (Pseudomonasvirus phi6) |
no annotation | 4 | SER A 741SER A 739TYR A 637ILE A 633 | None | 1.26A | 4ms4A-4btgA:undetectable | 4ms4A-4btgA:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fl0 | AMINOTRANSFERASEALD1 (Arabidopsisthaliana) |
PF00155(Aminotran_1_2) | 4 | SER A 252SER A 280TYR A 126ILE A 121 | None | 1.34A | 4ms4A-4fl0A:3.0 | 4ms4A-4fl0A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h53 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | SER A 228SER A 279TYR A 423TRP A 352 | None | 1.14A | 4ms4A-4h53A:undetectable | 4ms4A-4h53A:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4het | HYPOTHETICALGLYCOSIDE HYDROLASE (Bacteroidesthetaiotaomicron) |
PF13201(PCMD) | 4 | SER A 347SER A 349ILE A 209GLU A 194 | None | 1.26A | 4ms4A-4hetA:undetectable | 4ms4A-4hetA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9w | PROLINE RACEMASEFAMILY PROTEIN (Pseudomonasprotegens) |
PF05544(Pro_racemase) | 4 | SER A 9SER A 98ILE A 20GLU A 293 | None | 1.34A | 4ms4A-4j9wA:undetectable | 4ms4A-4j9wA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k05 | CONSERVEDHYPOTHETICALEXPORTED PROTEIN (Bacteroidesfragilis) |
PF07075(DUF1343) | 4 | SER A 255HIS A 94TYR A 267GLU A 93 | None | 1.36A | 4ms4A-4k05A:4.4 | 4ms4A-4k05A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kf7 | NUP188 (Thermothelomycesthermophila) |
PF10487(Nup188) | 4 | SER A 512SER A 559TYR A 579ILE A 613 | None | 1.19A | 4ms4A-4kf7A:undetectable | 4ms4A-4kf7A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kn5 | METHYLTHIOADENOSINENUCLEOSIDASE (Weissellaparamesenteroides) |
PF01048(PNP_UDP_1) | 4 | SER A 219SER A 74TYR A 133ILE A 91 | None | 1.25A | 4ms4A-4kn5A:4.7 | 4ms4A-4kn5A:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4koa | 1,5-ANHYDRO-D-FRUCTOSE REDUCTASE (Sinorhizobiummeliloti) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | SER A 70SER A 10ILE A 18GLU A 15 | NDP A 500 (-4.9A)NDP A 500 (-3.9A)NoneNone | 1.36A | 4ms4A-4koaA:5.1 | 4ms4A-4koaA:24.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4mrm | GAMMA-AMINOBUTYRICACID TYPE B RECEPTORSUBUNIT 1 (Homo sapiens) |
PF01094(ANF_receptor) | 5 | TRP A 65SER A 130SER A 153HIS A 170GLU A 349 | 2BY A 501 (-3.6A)2BY A 501 (-3.0A)2BY A 501 (-2.6A)2BY A 501 (-4.1A)2BY A 501 (-3.5A) | 0.22A | 4ms4A-4mrmA:58.0 | 4ms4A-4mrmA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n54 | INOSITOLDEHYDROGENASE (Lactobacilluscasei) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | SER A 78HIS A 81ILE A 185GLU A 98 | NAI A 401 (-3.1A)NAI A 401 (-4.0A)NoneNAI A 401 (-3.3A) | 1.03A | 4ms4A-4n54A:5.2 | 4ms4A-4n54A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nmn | REPLICATIVE DNAHELICASE (Aquifexaeolicus) |
PF00772(DnaB)PF03796(DnaB_C) | 4 | SER A 275SER A 252ILE A 264GLU A 267 | None | 1.25A | 4ms4A-4nmnA:3.7 | 4ms4A-4nmnA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p2l | SULFHYDRYL OXIDASE 1 (Rattusnorvegicus) |
PF00085(Thioredoxin)PF04777(Evr1_Alr) | 4 | SER A 472SER A 474HIS A 422GLU A 426 | None | 1.13A | 4ms4A-4p2lA:undetectable | 4ms4A-4p2lA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p7w | L-PROLINECIS-4-HYDROXYLASE (Mesorhizobiumjaponicum) |
PF05118(Asp_Arg_Hydrox)PF05373(Pro_3_hydrox_C) | 4 | SER A 155HIS A 106ILE A 97TRP A 40 | None CO A 301 ( 3.3A)NoneAKG A 302 (-4.2A) | 1.09A | 4ms4A-4p7wA:undetectable | 4ms4A-4p7wA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q28 | PERIPLAKIN (Homo sapiens) |
PF00681(Plectin) | 4 | SER A1652HIS A1650TYR A1738GLU A1706 | None | 1.36A | 4ms4A-4q28A:undetectable | 4ms4A-4q28A:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 4 | SER A 49SER A 54TYR A 125GLU A 56 | None | 1.25A | 4ms4A-4tr6A:undetectable | 4ms4A-4tr6A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzw | ENDO-GLUCANASECHIMERA C10 (Geobacillus sp.70PC53;unculturedbacterium) |
PF00150(Cellulase) | 4 | SER A 234SER A 273TRP A 264GLU A 230 | NoneNoneEPE A 404 ( 4.1A)EPE A 404 (-4.3A) | 1.30A | 4ms4A-4xzwA:undetectable | 4ms4A-4xzwA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d2j | 4-OXALOCROTONATEDECARBOXYLASE NAHK (Pseudomonasputida) |
no annotation | 4 | SER A 164SER A 146HIS A 105ILE A 27 | 0L1 A 303 (-2.6A)0L1 A 303 ( 4.7A)NoneNone | 1.29A | 4ms4A-5d2jA:undetectable | 4ms4A-5d2jA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dt5 | BETA-GLUCOSIDASE (Exiguobacteriumantarcticum) |
PF00232(Glyco_hydro_1) | 4 | TRP A 118SER A 170ILE A 31TRP A 32 | None | 1.23A | 4ms4A-5dt5A:undetectable | 4ms4A-5dt5A:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fip | GH5 CELLULASE (unidentified) |
PF00150(Cellulase)PF03424(CBM_17_28) | 4 | SER A 257SER A 238ILE A 154GLU A 294 | None | 1.23A | 4ms4A-5fipA:2.1 | 4ms4A-5fipA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gje | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 6 (Homo sapiens) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 4 | SER B1025HIS B1205TYR B1029GLU B1067 | None | 1.12A | 4ms4A-5gjeB:undetectable | 4ms4A-5gjeB:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1k | GEM-ASSOCIATEDPROTEIN 5 (Homo sapiens) |
PF00400(WD40)PF12894(ANAPC4_WD40) | 4 | SER A 200HIS A 194ILE A 253TRP A 254 | None | 1.06A | 4ms4A-5h1kA:undetectable | 4ms4A-5h1kA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5igp | MACROLIDE2'-PHOSPHOTRANSFERASE (Escherichiacoli) |
PF01636(APH) | 4 | SER A 221HIS A 205TYR A 36ILE A 38 | GDP A 401 ( 4.7A)GDP A 401 (-4.4A)NoneGDP A 401 (-4.2A) | 1.21A | 4ms4A-5igpA:undetectable | 4ms4A-5igpA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mrw | POTASSIUM-TRANSPORTING ATPASEATP-BINDING SUBUNIT (Escherichiacoli) |
PF00122(E1-E2_ATPase)PF00702(Hydrolase) | 4 | SER B 384SER B 341ILE B 443GLU B 348 | None | 1.30A | 4ms4A-5mrwB:4.3 | 4ms4A-5mrwB:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfh | METHIONYL-TRNASYNTHETASE, PUTATIVE (Trypanosomabrucei) |
no annotation | 4 | SER A 585HIS A 545TYR A 593ILE A 257 | None | 0.83A | 4ms4A-5nfhA:3.2 | 4ms4A-5nfhA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nnz | DYNEIN ASSEMBLYFACTOR WITH WDRREPEAT DOMAINS 1 (Homo sapiens) |
no annotation | 4 | SER B 392HIS B 386ILE B 413TRP B 414 | None | 1.33A | 4ms4A-5nnzB:undetectable | 4ms4A-5nnzB:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nuv | AUTOPHAGY-RELATEDPROTEIN 16-1 (Homo sapiens) |
PF00400(WD40) | 4 | TRP A 435SER A 390HIS A 407ILE A 455 | None | 1.11A | 4ms4A-5nuvA:undetectable | 4ms4A-5nuvA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ue1 | 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE (Aliivibriofischeri) |
PF01048(PNP_UDP_1) | 4 | SER A 197SER A 76ILE A 50GLU A 173 | 9DA A 301 (-3.2A)TRS A 302 (-2.8A)TRS A 302 ( 4.8A)TRS A 302 ( 4.6A) | 1.11A | 4ms4A-5ue1A:2.6 | 4ms4A-5ue1A:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ujw | TRIOSEPHOSPHATEISOMERASE (Francisellatularensis) |
PF00121(TIM) | 4 | SER A 98SER A 94HIS A 93ILE A 170 | NoneNoneNone13P A 301 ( 4.6A) | 1.19A | 4ms4A-5ujwA:undetectable | 4ms4A-5ujwA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur2 | BIFUNCTIONAL PROTEINPUTA (Bdellovibriobacteriovorus) |
PF00171(Aldedh)PF01619(Pro_dh) | 4 | SER A 907SER A 909HIS A 70GLU A 66 | None | 1.10A | 4ms4A-5ur2A:2.6 | 4ms4A-5ur2A:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7p | OXAC (Penicilliumoxalicum) |
no annotation | 4 | SER A 245HIS A 277TYR A 198GLU A 276 | SAM A 501 (-3.5A)NoneSAM A 501 (-4.8A)None | 0.99A | 4ms4A-5w7pA:3.6 | 4ms4A-5w7pA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wru | PROBABLE INORGANICPYROPHOSPHATASE (Plasmodiumfalciparum) |
no annotation | 4 | SER A 109HIS A 112ILE A 139TRP A 111 | None | 1.33A | 4ms4A-5wruA:undetectable | 4ms4A-5wruA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zln | TOLL-LIKE RECEPTOR 9 (Mus musculus) |
no annotation | 4 | SER A 149SER A 131ILE A 71TRP A 96 | None | 1.33A | 4ms4A-5zlnA:undetectable | 4ms4A-5zlnA:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6br6 | NEURAMINIDASE (Influenza Avirus) |
no annotation | 4 | SER A 228SER A 279TYR A 423TRP A 352 | None | 1.11A | 4ms4A-6br6A:undetectable | 4ms4A-6br6A:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6br9 | PROTEIN A6 HOMOLOG (Fowlpox virus) |
no annotation | 4 | SER A 272SER A 268TYR A 348ILE A 225 | None | 1.19A | 4ms4A-6br9A:undetectable | 4ms4A-6br9A:11.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cwo | RIBONUCLEOTIDEREDUCTASE (Flavobacteriumjohnsoniae) |
no annotation | 4 | TRP A 30HIS A 100TYR A 29ILE A 25 | None MN A 401 (-3.5A)NoneNone | 1.00A | 4ms4A-6cwoA:undetectable | 4ms4A-6cwoA:11.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cwp | RIBONUCLEOTIDEREDUCTASE (Flavobacteriumjohnsoniae) |
no annotation | 4 | TRP A 30HIS A 100TYR A 29ILE A 25 | None MN A 401 (-3.3A)NoneNone | 0.99A | 4ms4A-6cwpA:undetectable | 4ms4A-6cwpA:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6emr | - (-) |
no annotation | 4 | SER A 350SER A 347TRP A 344GLU A 345 | None | 1.35A | 4ms4A-6emrA:undetectable | 4ms4A-6emrA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN4 (Mus musculus) |
no annotation | 4 | SER M 292HIS M 293ILE M 402GLU M 378 | None | 1.14A | 4ms4A-6g2jM:undetectable | 4ms4A-6g2jM:13.31 |