SIMILAR PATTERNS OF AMINO ACIDS FOR 4MMD_A_29EA603
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cpt | CYTOCHROME P450-TERP (Pseudomonas sp.) |
PF00067(p450) | 5 | VAL A 308ALA A 307GLY A 416SER A 276GLY A 278 | HEM A 430 ( 4.7A)NoneNoneNoneNone | 1.36A | 4mmdA-1cptA:0.0 | 4mmdA-1cptA:22.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbi | AK.1 SERINE PROTEASE (Bacillus sp.Ak1) |
PF00082(Peptidase_S8) | 5 | ASP A 48VAL A 211ALA A 220TYR A 219GLY A 92 | CA A 701 (-2.2A)NoneNoneNoneNone | 1.03A | 4mmdA-1dbiA:0.1 | 4mmdA-1dbiA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6y | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanosarcinabarkeri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 5 | ASP A1488ALA A1474GLY A1507SER A1445GLY A1446 | None | 1.35A | 4mmdA-1e6yA:2.4 | 4mmdA-1e6yA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gco | GLUCOSEDEHYDROGENASE (Bacillusmegaterium) |
PF13561(adh_short_C2) | 5 | ALA A 159TYR A 158GLY A 187SER A 161GLY A 163 | NoneNAD A 601 (-4.5A)NoneNoneNone | 1.31A | 4mmdA-1gcoA:undetectable | 4mmdA-1gcoA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz7 | LIPASE 2 (Diutina rugosa) |
PF00135(COesterase) | 5 | PRO A 65VAL A 296ALA A 298PHE A 87GLY A 67 | NoneNoneNAG A1536 ( 4.6A)NoneNone | 1.09A | 4mmdA-1gz7A:0.8 | 4mmdA-1gz7A:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7k | CATALASE (Proteusmirabilis) |
PF00199(Catalase)PF06628(Catalase-rel) | 5 | VAL A 211TYR A 199GLY A 321PHE A 201SER A 325 | None | 1.30A | 4mmdA-1h7kA:2.3 | 4mmdA-1h7kA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j32 | ASPARTATEAMINOTRANSFERASE (Phormidiumlapideum) |
PF00155(Aminotran_1_2) | 5 | PRO A 326TYR A 323GLY A 353PHE A 325SER A 365 | None | 1.35A | 4mmdA-1j32A:0.0 | 4mmdA-1j32A:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ng0 | COAT PROTEIN (Cocksfootmottle virus) |
PF00729(Viral_coat) | 5 | VAL A 180ALA A 179GLY A 233SER A 166GLY A 163 | VAL A 180 ( 0.6A)ALA A 179 ( 0.0A)GLY A 233 ( 0.0A)SER A 166 ( 0.0A)GLY A 163 ( 0.0A) | 1.33A | 4mmdA-1ng0A:undetectable | 4mmdA-1ng0A:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1np7 | DNA PHOTOLYASE (Synechocystissp. PCC 6803) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 5 | TYR A 398ALA A 300TYR A 303PHE A 295GLY A 394 | None | 1.15A | 4mmdA-1np7A:undetectable | 4mmdA-1np7A:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pq5 | TRYPSIN (Fusariumoxysporum) |
PF00089(Trypsin) | 5 | PRO A 198VAL A 210ALA A 209GLY A 139GLY A 42 | NoneARG A 703 (-4.5A)NoneNoneNone | 1.19A | 4mmdA-1pq5A:undetectable | 4mmdA-1pq5A:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwk | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C1 (Caenorhabditiselegans) |
PF00248(Aldo_ket_red) | 5 | PRO A 17VAL A 18ALA A 259GLY A 42GLY A 20 | None | 1.28A | 4mmdA-1qwkA:undetectable | 4mmdA-1qwkA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ulv | GLUCODEXTRANASE (Arthrobacterglobiformis) |
PF00723(Glyco_hydro_15)PF09136(Glucodextran_B)PF09137(Glucodextran_N)PF09985(Glucodextran_C) | 5 | PRO A 945ALA A 934GLY A 974SER A 936GLY A 939 | None | 1.21A | 4mmdA-1ulvA:undetectable | 4mmdA-1ulvA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w5d | PENICILLIN-BINDINGPROTEIN (Bacillussubtilis) |
PF02113(Peptidase_S13) | 5 | ASP A 200PRO A 176VAL A 174ALA A 185GLY A 227 | None | 1.36A | 4mmdA-1w5dA:undetectable | 4mmdA-1w5dA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xje | RIBONUCLEOTIDEREDUCTASE,B12-DEPENDENT (Thermotogamaritima) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC) | 5 | ALA A 617TYR A 614GLY A 246PHE A 247GLY A 624 | None | 1.13A | 4mmdA-1xjeA:undetectable | 4mmdA-1xjeA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z68 | FIBROBLASTACTIVATION PROTEIN,ALPHA SUBUNIT (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | VAL A 540TYR A 541GLY A 593SER A 624GLY A 627 | None | 1.09A | 4mmdA-1z68A:undetectable | 4mmdA-1z68A:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zoi | ESTERASE (Pseudomonasputida) |
PF00561(Abhydrolase_1) | 5 | VAL A 124ALA A 123GLY A 199PHE A 203GLY A 99 | None | 1.36A | 4mmdA-1zoiA:undetectable | 4mmdA-1zoiA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2atz | H. PYLORI PREDICTEDCODING REGION HP0184 (Helicobacterpylori) |
PF08966(DUF1882) | 5 | TYR A 78ASP A 77PRO A 143ALA A 139GLY A 80 | NoneDGT A 201 (-2.9A)NoneNoneNone | 1.34A | 4mmdA-2atzA:undetectable | 4mmdA-2atzA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b7h | HEMOGLOBIN BETACHAIN (Cerdocyon thous) |
PF00042(Globin) | 5 | PRO B 124VAL B 126ALA B 128TYR B 130GLY B 119 | None | 1.35A | 4mmdA-2b7hB:undetectable | 4mmdA-2b7hB:14.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buc | DIPEPTIDYL PEPTIDASEIV (Sus scrofa) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | VAL A 546TYR A 547GLY A 599SER A 630GLY A 633 | NoneSO4 A1769 ( 4.5A)NDG A1685 (-4.6A)SO4 A1769 ( 3.0A)None | 0.96A | 4mmdA-2bucA:undetectable | 4mmdA-2bucA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cev | PROTEIN (ARGINASE) ([Bacillus]caldovelox) |
PF00491(Arginase) | 5 | ASP A 226PRO A 274ALA A 283GLY A 239GLY A 23 | MN A 302 (-2.9A)NoneNoneNoneNone | 1.26A | 4mmdA-2cevA:undetectable | 4mmdA-2cevA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d5l | DIPEPTIDYLAMINOPEPTIDASE IV,PUTATIVE (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | VAL A 517TYR A 518GLY A 572SER A 603GLY A 606 | None | 1.03A | 4mmdA-2d5lA:undetectable | 4mmdA-2d5lA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dne | DIHYDROLIPOYLLYSINE-RESIDUEACETYLTRANSFERASECOMPONENT OFPYRUVATEDEHYDROGENASECOMPLEX (Homo sapiens) |
PF00364(Biotin_lipoyl) | 5 | ASP A 72VAL A 66ALA A 67GLY A 22GLY A 69 | None | 1.20A | 4mmdA-2dneA:undetectable | 4mmdA-2dneA:11.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ix4 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE (Arabidopsisthaliana) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | VAL A 232ALA A 233GLY A 197PHE A 198SER A 189 | None | 1.26A | 4mmdA-2ix4A:undetectable | 4mmdA-2ix4A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nxo | HYPOTHETICAL PROTEINSCO4506 (Streptomycescoelicolor) |
PF02621(VitK2_biosynth) | 5 | VAL A 187ALA A 186GLY A 250PHE A 249GLY A 78 | None | 1.27A | 4mmdA-2nxoA:1.2 | 4mmdA-2nxoA:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p7n | PATHOGENICITY ISLAND1 EFFECTOR PROTEIN (Chromobacteriumviolaceum) |
PF06511(IpaD) | 5 | ASP A 259PRO A 267VAL A 264GLY A 274GLY A 277 | None | 1.20A | 4mmdA-2p7nA:undetectable | 4mmdA-2p7nA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yut | PUTATIVE SHORT-CHAINOXIDOREDUCTASE (Thermusthermophilus) |
PF00106(adh_short) | 5 | PRO A 123VAL A 126ALA A 135TYR A 134GLY A 139 | None | 1.32A | 4mmdA-2yutA:undetectable | 4mmdA-2yutA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a28 | L-2.3-BUTANEDIOLDEHYDROGENASE (Corynebacteriumglutamicum) |
no annotation | 5 | PRO C 226VAL C 229ALA C 230TYR C 182GLY C 15 | None | 1.09A | 4mmdA-3a28C:undetectable | 4mmdA-3a28C:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aje | PUTATIVEUNCHARACTERIZEDPROTEIN ST1526 (Sulfurisphaeratokodaii) |
PF01300(Sua5_yciO_yrdC)PF03481(SUA5) | 5 | VAL A 294ALA A 295GLY A 317PHE A 318GLY A 324 | None | 1.09A | 4mmdA-3ajeA:undetectable | 4mmdA-3ajeA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3auf | GLYCINAMIDERIBONUCLEOTIDETRANSFORMYLASE 1 (Symbiobacteriumtoebii) |
PF00551(Formyl_trans_N) | 5 | ASP A 37VAL A 34ALA A 54GLY A 88GLY A 43 | None | 1.26A | 4mmdA-3aufA:undetectable | 4mmdA-3aufA:18.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aut | GLUCOSE1-DEHYDROGENASE 4 (Bacillusmegaterium) |
PF13561(adh_short_C2) | 5 | ALA A 159TYR A 158GLY A 187SER A 161GLY A 163 | None | 1.33A | 4mmdA-3autA:undetectable | 4mmdA-3autA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayf | NITRIC OXIDEREDUCTASE (Geobacillusstearothermophilus) |
PF00115(COX1) | 5 | VAL A 667ALA A 666TYR A 670GLY A 306PHE A 309 | None | 1.25A | 4mmdA-3ayfA:undetectable | 4mmdA-3ayfA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bjr | PUTATIVECARBOXYLESTERASE (Lactobacillusplantarum) |
PF07859(Abhydrolase_3) | 5 | TYR A 18VAL A 47ALA A 48GLY A 17SER A 52 | NoneGOL A 265 (-3.9A)GOL A 265 (-3.3A)NoneNone | 1.08A | 4mmdA-3bjrA:undetectable | 4mmdA-3bjrA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dnf | 4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATEREDUCTASE (Aquifexaeolicus) |
PF02401(LYTB) | 5 | VAL A 20ALA A 19GLY A 11PHE A 12GLY A 15 | NoneNoneNoneNoneF3S A2302 (-3.4A) | 1.24A | 4mmdA-3dnfA:undetectable | 4mmdA-3dnfA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ezu | GGDEF DOMAIN PROTEIN (Geobactersulfurreducens) |
PF00990(GGDEF) | 5 | ASP A 313ALA A 205TYR A 204GLY A 315SER A 201 | None | 1.35A | 4mmdA-3ezuA:undetectable | 4mmdA-3ezuA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd5 | SELENIDE, WATERDIKINASE 1 (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | VAL A 302ALA A 305GLY A 28PHE A 310GLY A 307 | None | 1.33A | 4mmdA-3fd5A:undetectable | 4mmdA-3fd5A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fou | QUINOL-CYTOCHROME CREDUCTASE, RIESKEIRON-SULFUR SUBUNIT (Thermusthermophilus) |
PF00355(Rieske) | 5 | VAL A 126ALA A 121GLY A 78PHE A 108GLY A 124 | None | 1.36A | 4mmdA-3fouA:undetectable | 4mmdA-3fouA:15.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg7 | UNCHARACTERIZEDMETALLOPROTEIN (Deinococcusradiodurans) |
PF01026(TatD_DNase) | 5 | ASP A 3PRO A 14VAL A 17ALA A 18GLY A 195 | None | 1.01A | 4mmdA-3gg7A:undetectable | 4mmdA-3gg7A:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic1 | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Haemophilusinfluenzae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | PRO A 293GLY A 328PHE A 294SER A 290GLY A 291 | None | 1.27A | 4mmdA-3ic1A:undetectable | 4mmdA-3ic1A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iec | SERINE/THREONINE-PROTEIN KINASE MARK2 (Homo sapiens) |
PF00069(Pkinase)PF00627(UBA) | 5 | PRO A 214VAL A 238TYR A 241PHE A 250SER A 247 | None | 1.30A | 4mmdA-3iecA:undetectable | 4mmdA-3iecA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3io0 | ETUB PROTEIN (Clostridiumkluyveri) |
PF00936(BMC) | 5 | PRO A 227VAL A 230ALA A 225GLY A 293GLY A 194 | None | 1.34A | 4mmdA-3io0A:undetectable | 4mmdA-3io0A:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhf | SERINE RECOMBINASE (Sulfolobussolfataricus) |
PF00239(Resolvase) | 5 | ASP A 91PRO A 123VAL A 120ALA A 121GLY A 95 | None | 1.13A | 4mmdA-3lhfA:undetectable | 4mmdA-3lhfA:13.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mc1 | PREDICTEDPHOSPHATASE, HADFAMILY (Clostridiumacetobutylicum) |
PF13419(HAD_2) | 5 | ASP A 10VAL A 105ALA A 106SER A 108GLY A 132 | GOL A 303 ( 3.8A)NoneNoneNoneNone | 1.12A | 4mmdA-3mc1A:undetectable | 4mmdA-3mc1A:17.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mpn | TRANSPORTER (Aquifexaeolicus) |
PF00209(SNF) | 6 | PRO A 101VAL A 104ALA A 105TYR A 108PHE A 259SER A 356 | NoneNoneNoneLEU A 601 (-4.5A)LEU A 601 (-3.6A)None | 0.45A | 4mmdA-3mpnA:60.2 | 4mmdA-3mpnA:98.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9s | CARNITINYL-COADEHYDRATASE (Mycobacteriumavium) |
PF00378(ECH_1) | 5 | ASP A 82PRO A 5ALA A 32SER A 34GLY A 36 | None | 1.21A | 4mmdA-3r9sA:undetectable | 4mmdA-3r9sA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sd7 | PUTATIVE PHOSPHATASE (Clostridioidesdifficile) |
PF13419(HAD_2) | 5 | ASP A 13VAL A 107ALA A 108SER A 110GLY A 134 | NoneNoneNoneNoneGOL A 221 (-4.2A) | 1.03A | 4mmdA-3sd7A:undetectable | 4mmdA-3sd7A:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7b | ACETYLGLUTAMATEKINASE (Yersinia pestis) |
PF00696(AA_kinase) | 5 | PRO A 230VAL A 231ALA A 224GLY A 172GLY A 228 | None | 1.24A | 4mmdA-3t7bA:undetectable | 4mmdA-3t7bA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tg9 | PENICILLIN-BINDINGPROTEIN (Bacillushalodurans) |
PF00144(Beta-lactamase) | 5 | ASP A 234ALA A 200GLY A 188PHE A 190GLY A 50 | None | 1.07A | 4mmdA-3tg9A:undetectable | 4mmdA-3tg9A:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tkk | PREDICTEDACETAMIDASE/FORMAMIDASE (Caldanaerobactersubterraneus) |
PF03069(FmdA_AmdA) | 5 | ASP A 182VAL A 84ALA A 85GLY A 196GLY A 88 | ZN A 301 ( 2.4A)NoneNoneNoneNone | 1.32A | 4mmdA-3tkkA:undetectable | 4mmdA-3tkkA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u07 | UNCHARACTERIZEDPROTEIN VPA0106 (Vibrioparahaemolyticus) |
PF06742(DUF1214)PF06863(DUF1254) | 5 | VAL A 157ALA A 140GLY A 117SER A 227GLY A 226 | None | 1.20A | 4mmdA-3u07A:undetectable | 4mmdA-3u07A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vss | BETA-FRUCTOFURANOSIDASE (Microbacteriumsaccharophilum) |
PF02435(Glyco_hydro_68) | 5 | TYR A 418ASP A 417ALA A 55TYR A 54GLY A 411 | NoneNoneFRU A 603 ( 3.9A)NoneNone | 1.35A | 4mmdA-3vssA:undetectable | 4mmdA-3vssA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuk | ENDOPEPTIDASE,PEPTIDASE FAMILY M13 (Mycobacteriumtuberculosis) |
PF01431(Peptidase_M13)PF05649(Peptidase_M13_N) | 5 | VAL A 596ALA A 482TYR A 484GLY A 567GLY A 486 | None | 1.13A | 4mmdA-3zukA:undetectable | 4mmdA-3zukA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyt | ESTERASE A (Paenarthrobacternitroguajacolicus) |
PF00144(Beta-lactamase) | 5 | VAL A 283GLY A 63PHE A 305SER A 106GLY A 302 | None | 1.23A | 4mmdA-3zytA:undetectable | 4mmdA-3zytA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyv | AOX3 (Mus musculus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 5 | ASP A1089PRO A1015ALA A1143TYR A1141PHE A1014 | None | 1.31A | 4mmdA-3zyvA:undetectable | 4mmdA-3zyvA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btp | P1 (Pseudomonasphage phi8) |
no annotation | 5 | PRO A 650ALA A 648TYR A 638GLY A 716GLY A 725 | None | 0.76A | 4mmdA-4btpA:undetectable | 4mmdA-4btpA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4btp | P1 (Pseudomonasphage phi8) |
no annotation | 5 | PRO A 650VAL A 636ALA A 648TYR A 638GLY A 725 | None | 0.90A | 4mmdA-4btpA:undetectable | 4mmdA-4btpA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dz4 | AGMATINASE (Burkholderiathailandensis) |
PF00491(Arginase) | 5 | ASP A 242PRO A 289ALA A 298GLY A 255GLY A 65 | MN A 401 ( 2.8A)EDO A 405 ( 4.7A)NoneNoneNone | 1.32A | 4mmdA-4dz4A:undetectable | 4mmdA-4dz4A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2o | ALPHA-AMYLASE (Geobacillusthermoleovorans) |
PF00128(Alpha-amylase) | 5 | ASP A 113VAL A 57TYR A 65GLY A 117GLY A 68 | None | 1.35A | 4mmdA-4e2oA:undetectable | 4mmdA-4e2oA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hr6 | LECTIN (Trichosanthesanguina) |
PF00652(Ricin_B_lectin) | 5 | ASP C 16TYR C 176GLY C 211SER C 177GLY C 179 | None | 1.15A | 4mmdA-4hr6C:undetectable | 4mmdA-4hr6C:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l8k | PUTATIVE PEPTIDASE (Parabacteroidesmerdae) |
PF03572(Peptidase_S41)PF14684(Tricorn_C1) | 5 | VAL A 172TYR A 143PHE A 246SER A 145GLY A 177 | None | 1.23A | 4mmdA-4l8kA:undetectable | 4mmdA-4l8kA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mq0 | PARKIA BIGLOBOSALECTIN (PBL) (Parkiabiglobosa) |
PF01419(Jacalin) | 5 | ASP A 355ALA A 429TYR A 432GLY A 357GLY A 349 | NoneNoneMMA A 502 (-3.8A)NoneNone | 1.32A | 4mmdA-4mq0A:undetectable | 4mmdA-4mq0A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mq0 | PARKIA BIGLOBOSALECTIN (PBL) (Parkiabiglobosa) |
PF01419(Jacalin) | 5 | VAL A 390TYR A 378GLY A 437SER A 412GLY A 376 | None | 1.10A | 4mmdA-4mq0A:undetectable | 4mmdA-4mq0A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psp | ALPHA-FUCOSIDASEGH29 (Fusariumgraminearum) |
PF01120(Alpha_L_fucos)PF16757(Fucosidase_C) | 5 | ASP A 303VAL A 167ALA A 120TYR A 32GLY A 30 | GOL A 622 (-2.6A)NoneNoneNoneNone | 0.98A | 4mmdA-4pspA:undetectable | 4mmdA-4pspA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q1v | PUTATIVE DIPEPTIDYLAMINOPEPTIDASE IV (Bacteroidesovatus) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | VAL A 517TYR A 518GLY A 572SER A 603GLY A 606 | NonePEG A 801 ( 4.0A)NoneNoneNone | 1.01A | 4mmdA-4q1vA:undetectable | 4mmdA-4q1vA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qav | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Neisseriameningitidis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 5 | VAL A 351ALA A 350TYR A 352GLY A 236GLY A 346 | None | 1.24A | 4mmdA-4qavA:undetectable | 4mmdA-4qavA:23.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qax | 2,3-BISPHOSPHOGLYCERATE-INDEPENDENTPHOSPHOGLYCERATEMUTASE (Staphylococcusaureus) |
PF01676(Metalloenzyme)PF06415(iPGM_N) | 5 | ASP A 230ALA A 222TYR A 224GLY A 184GLY A 219 | None | 1.27A | 4mmdA-4qaxA:undetectable | 4mmdA-4qaxA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r1d | UNCHARACTERIZEDPROTEIN (Pseudomonasaeruginosa) |
no annotation | 5 | VAL B 261ALA B 262GLY A 89SER B 264GLY B 270 | None | 1.29A | 4mmdA-4r1dB:undetectable | 4mmdA-4r1dB:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rkk | LAFORIN (Homo sapiens) |
PF00686(CBM_20)PF00782(DSPc) | 5 | PRO A 246VAL A 249ALA A 248GLY A 322PHE A 317 | None | 1.25A | 4mmdA-4rkkA:undetectable | 4mmdA-4rkkA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9u | NA(+)-TRANSLOCATINGNADH-QUINONEREDUCTASE SUBUNIT F (Vibrio cholerae) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | PRO A 161GLY A 166PHE A 162SER A 261GLY A 262 | None | 1.23A | 4mmdA-4u9uA:undetectable | 4mmdA-4u9uA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xn3 | TAIL SPIKE PROTEIN (Salmonellavirus HK620) |
no annotation | 5 | ASP A 561VAL A 615ALA A 614GLY A 556PHE A 584 | None | 1.18A | 4mmdA-4xn3A:undetectable | 4mmdA-4xn3A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnu | INTEGRAL MEMBRANEPROTEIN-DOPAMINETRANSPORTER (Drosophilamelanogaster) |
PF00209(SNF) | 5 | ASP A 46GLY A 322PHE A 325SER A 422GLY A 425 | 41U A 605 ( 3.3A)41U A 605 ( 4.1A)41U A 605 ( 4.7A)None41U A 605 ( 3.7A) | 0.94A | 4mmdA-4xnuA:41.0 | 4mmdA-4xnuA:29.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xnu | INTEGRAL MEMBRANEPROTEIN-DOPAMINETRANSPORTER (Drosophilamelanogaster) |
PF00209(SNF) | 6 | ASP A 46VAL A 120TYR A 124GLY A 322SER A 422GLY A 425 | 41U A 605 ( 3.3A)41U A 605 (-4.2A)41U A 605 ( 3.8A)41U A 605 ( 4.1A)None41U A 605 ( 3.7A) | 0.82A | 4mmdA-4xnuA:41.0 | 4mmdA-4xnuA:29.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y9v | PARTICLE-ASSOCIATEDLYASE (Acinetobactervirus AP22) |
no annotation | 5 | VAL A 404ALA A 405GLY A 420SER A 385GLY A 407 | NoneNoneNoneNone49S A 814 (-3.5A) | 1.22A | 4mmdA-4y9vA:undetectable | 4mmdA-4y9vA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yu4 | HEMOGLOBIN (Helogaleparvula) |
PF00042(Globin) | 5 | PRO B 124VAL B 126ALA B 128TYR B 130GLY B 119 | None | 1.36A | 4mmdA-4yu4B:undetectable | 4mmdA-4yu4B:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z26 | PUTATIVE GMC-TYPEOXIDOREDUCTASE R135 (Acanthamoebapolyphagamimivirus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | PRO A 612ALA A 609GLY A 440SER A 607GLY A 580 | None | 1.02A | 4mmdA-4z26A:undetectable | 4mmdA-4z26A:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zz7 | METHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Oceanimonasdoudoroffii) |
PF00171(Aldedh) | 5 | TYR A 110VAL A 164ALA A 65GLY A 464GLY A 113 | None | 1.11A | 4mmdA-4zz7A:undetectable | 4mmdA-4zz7A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bug | PHOSPHATIDYLINOSITOL3,4,5-TRISPHOSPHATE3-PHOSPHATASE ANDDUAL-SPECIFICITYPROTEIN PHOSPHATASEPTEN (Homo sapiens) |
PF00782(DSPc)PF10409(PTEN_C2) | 5 | PRO A 190VAL A 191ALA A 192PHE A 278GLY A 251 | None | 1.15A | 4mmdA-5bugA:undetectable | 4mmdA-5bugA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bv9 | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Bacilluspumilus) |
PF02011(Glyco_hydro_48) | 5 | TYR A 160ASP A 153ALA A 187GLY A 614PHE A 613 | None | 1.34A | 4mmdA-5bv9A:1.4 | 4mmdA-5bv9A:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e6s | INTEGRIN ALPHA-LINTEGRIN BETA-2 (Homo sapiens) |
PF00092(VWA)PF00362(Integrin_beta)PF01839(FG-GAP)PF08441(Integrin_alpha2)PF17205(PSI_integrin) | 5 | TYR A 69VAL A 343ALA A 342GLY B 254SER A 101 | None | 1.27A | 4mmdA-5e6sA:undetectable | 4mmdA-5e6sA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ho9 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF16369(GH43_C) | 5 | TYR A 149VAL A 180ALA A 160SER A 151GLY A 162 | None | 1.15A | 4mmdA-5ho9A:undetectable | 4mmdA-5ho9A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hp6 | EXTRACELLULARARABINANASE (Geobacillusstearothermophilus) |
PF04616(Glyco_hydro_43)PF13385(Laminin_G_3)PF16369(GH43_C) | 5 | TYR A 149VAL A 180ALA A 160SER A 151GLY A 162 | None | 1.26A | 4mmdA-5hp6A:undetectable | 4mmdA-5hp6A:21.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5i6z | SODIUM-DEPENDENTSEROTONINTRANSPORTER (Homo sapiens) |
PF00209(SNF) | 7 | TYR A 95ASP A 98ALA A 173TYR A 176GLY A 338SER A 439GLY A 442 | None | 0.87A | 4mmdA-5i6zA:42.1 | 4mmdA-5i6zA:31.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m3x | ANGIOTENSINOGEN (Homo sapiens) |
no annotation | 5 | VAL A 95TYR A 357GLY A 443SER A 394GLY A 355 | None | 1.26A | 4mmdA-5m3xA:1.2 | 4mmdA-5m3xA:9.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mac | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE-OXYGENASE TYPE III (Methanococcoidesburtonii) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 5 | TYR A 206VAL A 213ALA A 178PHE A 232SER A 174 | None | 1.36A | 4mmdA-5macA:undetectable | 4mmdA-5macA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mc5 | XAA-PRO DIPEPTIDASE (Homo sapiens) |
no annotation | 5 | TYR A 382ASP A 153PRO A 327GLY A 381SER A 396 | GOL A 506 ( 4.5A)NoneNoneNoneNone | 1.24A | 4mmdA-5mc5A:undetectable | 4mmdA-5mc5A:9.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5olj | DIPEPTIDYL PEPTIDASEIV (Porphyromonasgingivalis) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | TYR A 597TYR A 511GLY A 562SER A 593GLY A 596 | NoneGOL A 801 (-4.4A)NoneGOL A 801 (-2.5A)None | 1.17A | 4mmdA-5oljA:undetectable | 4mmdA-5oljA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t6o | POLY-BETA-HYDROXYBUTERATE POLYMERASE (Cupriavidusnecator) |
PF07167(PhaC_N) | 5 | ASP A 254PRO A 579ALA A 215TYR A 228GLY A 206 | None | 1.31A | 4mmdA-5t6oA:undetectable | 4mmdA-5t6oA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8t | S-ADENOSYLMETHIONINESYNTHASE (Neisseriagonorrhoeae) |
PF00438(S-AdoMet_synt_N)PF02772(S-AdoMet_synt_M)PF02773(S-AdoMet_synt_C) | 5 | ASP A 243VAL A 11ALA A 167GLY A 245GLY A 14 | None | 1.32A | 4mmdA-5t8tA:undetectable | 4mmdA-5t8tA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ukp | DH522.1 FAB FRAGMENTHEAVY CHAIN (Macaca mulatta) |
no annotation | 5 | ASP H 32TYR H 97GLY H 52SER H 96GLY H 95 | None | 1.07A | 4mmdA-5ukpH:undetectable | 4mmdA-5ukpH:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5van | BETA-KLOTHO (Homo sapiens) |
no annotation | 5 | PRO A 242VAL A 245ALA A 246TYR A 250GLY A 270 | None | 1.25A | 4mmdA-5vanA:undetectable | 4mmdA-5vanA:9.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vrb | TRANSKETOLASE (Neisseriagonorrhoeae) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | TYR A 404PRO A 426VAL A 373TYR A 401GLY A 428 | None | 1.35A | 4mmdA-5vrbA:undetectable | 4mmdA-5vrbA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w0x | TIP41-LIKE PROTEIN (Mus musculus) |
no annotation | 5 | ASP A 115VAL A 248ALA A 247TYR A 214SER A 216 | None | 1.22A | 4mmdA-5w0xA:undetectable | 4mmdA-5w0xA:9.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wan | PYRIMIDINEMONOOXYGENASE RUTA (Escherichiacoli) |
PF00296(Bac_luciferase) | 5 | VAL A 6ALA A 46GLY A 14PHE A 335SER A 48 | NoneNoneNoneGOL A 406 (-4.9A)None | 1.31A | 4mmdA-5wanA:undetectable | 4mmdA-5wanA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wi9 | - (-) |
no annotation | 5 | PRO A 242VAL A 245ALA A 246TYR A 250GLY A 270 | None | 1.24A | 4mmdA-5wi9A:undetectable | 4mmdA-5wi9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x2o | TASTE RECEPTOR, TYPE1, MEMBER 3 (Oryzias latipes) |
PF01094(ANF_receptor) | 5 | VAL B 386ALA B 389GLY B 72SER B 169GLY B 146 | None | 1.33A | 4mmdA-5x2oB:0.9 | 4mmdA-5x2oB:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xuk | HOLO-[ACYL-CARRIER-PROTEIN] SYNTHASE (Helicobacterpylori) |
no annotation | 5 | VAL A 7ALA A 108PHE A 47SER A 41GLY A 45 | None | 1.16A | 4mmdA-5xukA:undetectable | 4mmdA-5xukA:9.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y8p | PROBABLE3-HYDROXYISOBUTYRATEDEHYDROGENASE (Mycobacteriumtuberculosis) |
no annotation | 5 | VAL A 45ALA A 41GLY A 13SER A 38GLY A 39 | GOL A 301 ( 4.9A)NoneNoneNoneNone | 1.24A | 4mmdA-5y8pA:undetectable | 4mmdA-5y8pA:11.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zby | HYDROGENASEMATURATION PROTEASEHYCI (Thermococcuskodakarensis) |
no annotation | 5 | VAL A 33ALA A 34GLY A 124PHE A 29GLY A 18 | None | 1.03A | 4mmdA-5zbyA:undetectable | 4mmdA-5zbyA:11.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehn | CARBOHYDRATEESTERASE MZ0003 (unidentifiedprokaryoticorganism) |
no annotation | 5 | PRO A 20VAL A 350ALA A 349TYR A 351GLY A 346 | None | 1.23A | 4mmdA-6ehnA:undetectable | 4mmdA-6ehnA:9.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eot | DIPEPTIDYL PEPTIDASE8 (Homo sapiens) |
no annotation | 5 | TYR A 759TYR A 669GLY A 723SER A 755GLY A 758 | None | 1.29A | 4mmdA-6eotA:undetectable | 4mmdA-6eotA:8.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eu6 | AMMONIUM TRANSPORTER (CandidatusKueneniastuttgartiensis) |
no annotation | 5 | PRO A 319ALA A 322GLY A 33PHE A 34GLY A 113 | None | 1.06A | 4mmdA-6eu6A:undetectable | 4mmdA-6eu6A:10.48 |