SIMILAR PATTERNS OF AMINO ACIDS FOR 4MMC_A_29JA604

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a05 3-ISOPROPYLMALATE
DEHYDROGENASE

(Acidithiobacillus
ferrooxidans) 		PF00180
(Iso_dh) 		4 ILE A   4
LEU A  24
ASP A  25
ASP A  28
 None
 0.85A 4mmcA-1a05A:
0.0		 4mmcA-1a05A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dqp GUANINE
PHOSPHORIBOSYLTRANSF
ERASE

(Giardia
intestinalis) 		PF00156
(Pribosyltran) 		4 ILE A 137
PHE A 107
LEU A  68
THR A  64
 None
 1.03A 4mmcA-1dqpA:
0.0		 4mmcA-1dqpA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3b ATP-DEPENDENT
PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Thermus
thermophilus) 		PF01293
(PEPCK_ATP) 		4 PHE A 506
LEU A 353
ASP A 348
THR A 236
 None
None
None
PO4  A2003 (-4.1A)
 1.09A 4mmcA-1j3bA:
undetectable		 4mmcA-1j3bA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k4y LIVER
CARBOXYLESTERASE

(Oryctolagus
cuniculus) 		PF00135
(COesterase) 		4 ILE A 229
LEU A 327
ASP A 323
THR A 260
 None
 1.02A 4mmcA-1k4yA:
0.0		 4mmcA-1k4yA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0w ASPARTYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 ILE A 151
LEU A 529
ASP A 530
THR A 537
 None
 0.87A 4mmcA-1l0wA:
0.0		 4mmcA-1l0wA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nkp MAX PROTEIN

(Homo sapiens) 		PF00010
(HLH) 		4 LEU B 267
ASP B 266
ASP B 263
THR B 259
 None
 0.88A 4mmcA-1nkpB:
undetectable		 4mmcA-1nkpB:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjm IMPORTIN ALPHA-2
SUBUNIT

(Mus musculus) 		PF00514
(Arm)
PF16186
(Arm_3) 		4 ARG B 101
ILE B 115
PHE B 124
THR B  73
 None
 1.03A 4mmcA-1pjmB:
0.0		 4mmcA-1pjmB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q60 GENERAL
TRANSCRIPTION FACTOR
II-I

(Mus musculus) 		PF02946
(GTF2I) 		4 ARG A  57
ILE A  69
PHE A  16
LEU A  49
 None
 0.64A 4mmcA-1q60A:
undetectable		 4mmcA-1q60A:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q7l AMINOACYLASE-1

(Homo sapiens) 		PF01546
(Peptidase_M20) 		4 ILE B 390
PHE B 362
LEU B 336
THR A 181
 None
 0.99A 4mmcA-1q7lB:
undetectable		 4mmcA-1q7lB:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1um8 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX

(Helicobacter
pylori) 		PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ILE A 148
LEU A 321
ASP A 320
THR A 292
 None
 1.12A 4mmcA-1um8A:
0.0		 4mmcA-1um8A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwd FOLLICLE STIMULATING
HORMONE RECEPTOR

(Homo sapiens) 		PF01462
(LRRNT)
PF13306
(LRR_5) 		4 ILE C 160
PHE C 190
LEU C 177
THR C 228
 None
 1.08A 4mmcA-1xwdC:
undetectable		 4mmcA-1xwdC:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y7w HALOTOLERANT
ALPHA-TYPE CARBONIC
ANHYDRASE (DCA II)

(Dunaliella
salina) 		PF00194
(Carb_anhydrase) 		4 ARG A 234
ILE A 154
PHE A 230
LEU A  60
 None
 1.11A 4mmcA-1y7wA:
undetectable		 4mmcA-1y7wA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygg PHOSPHOENOLPYRUVATE
CARBOXYKINASE

(Actinobacillus
succinogenes) 		PF01293
(PEPCK_ATP) 		4 PHE A 517
LEU A 368
ASP A 363
THR A 252
 None
None
None
SO4  A4121 (-4.1A)
 1.07A 4mmcA-1yggA:
0.0		 4mmcA-1yggA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yz7 PROBABLE TRANSLATION
INITIATION FACTOR 2
ALPHA SUBUNIT

(Pyrococcus
abyssi) 		PF07541
(EIF_2_alpha) 		4 ARG A 225
ILE A 243
PHE A 216
THR A 177
 None
 1.11A 4mmcA-1yz7A:
undetectable		 4mmcA-1yz7A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2col BIFUNCTIONAL
HEMOLYSIN-ADENYLATE
CYCLASE

(Bordetella
pertussis) 		PF03497
(Anthrax_toxA) 		4 ILE A  27
PHE A  40
LEU A 283
THR A  57
 None
 0.96A 4mmcA-2colA:
0.3		 4mmcA-2colA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e47 TIME INTERVAL
MEASURING ENZYME
TIME

(Bombyx mori) 		PF00080
(Sod_Cu) 		4 ILE A  23
PHE A  49
LEU A  14
THR A  64
 None
 0.88A 4mmcA-2e47A:
undetectable		 4mmcA-2e47A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e8y AMYX PROTEIN

(Bacillus
subtilis) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 ARG A 573
ILE A 606
LEU A 263
THR A 220
 None
 1.03A 4mmcA-2e8yA:
undetectable		 4mmcA-2e8yA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN

(Mycobacterium
tuberculosis) 		PF00994
(MoCF_biosynth) 		4 ARG A   4
PHE A  37
LEU A 146
ASP A 147
 None
 1.02A 4mmcA-2g4rA:
undetectable		 4mmcA-2g4rA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j5c 1,8-CINEOLE SYNTHASE

(Salvia
fruticosa) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ILE A  92
PHE A 124
LEU A 272
ASP A 276
 None
 0.81A 4mmcA-2j5cA:
undetectable		 4mmcA-2j5cA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oer PROBABLE
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		4 ARG A  51
ILE A  69
PHE A  43
LEU A  73
 None
 0.77A 4mmcA-2oerA:
1.6		 4mmcA-2oerA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pwh SUCROSE ISOMERASE

([Pseudomonas]
mesoacidophila) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 ILE A 484
PHE A 516
LEU A 504
THR A 352
 None
 0.79A 4mmcA-2pwhA:
undetectable		 4mmcA-2pwhA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q2l SUPEROXIDE DISMUTASE

(Potentilla
atrosanguinea) 		PF00080
(Sod_Cu) 		4 ILE A  18
PHE A  44
LEU A   8
THR A  59
 None
 0.98A 4mmcA-2q2lA:
undetectable		 4mmcA-2q2lA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rb7 PEPTIDASE,
M20/M25/M40 FAMILY

(Desulfovibrio
alaskensis) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ILE A 250
PHE A 214
LEU A 261
ASP A 256
 None
 0.82A 4mmcA-2rb7A:
undetectable		 4mmcA-2rb7A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wg8 PUTATIVE
PHOSPHOLIPASE A2

(Oryza sativa) 		no annotation 4 ILE A 107
LEU A  54
ASP A  52
ASP A  55
 None
 1.06A 4mmcA-2wg8A:
2.3		 4mmcA-2wg8A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wny CONSERVED PROTEIN
MTH689

(Methanothermobacter
thermautotrophicus) 		PF01877
(RNA_binding) 		4 ARG A  76
ILE A 133
PHE A  69
LEU A  90
 None
 0.86A 4mmcA-2wnyA:
undetectable		 4mmcA-2wnyA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn6 THYROXINE-BINDING
GLOBULIN

(Homo sapiens) 		PF00079
(Serpin) 		4 ARG A  36
ILE A  53
PHE A  29
LEU A  57
 None
 0.90A 4mmcA-2xn6A:
undetectable		 4mmcA-2xn6A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ylk CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Ruminiclostridium
thermocellum) 		PF00942
(CBM_3) 		4 ARG A  40
ILE A 100
PHE A  43
LEU A  51
 None
 1.09A 4mmcA-2ylkA:
undetectable		 4mmcA-2ylkA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asi NEUREXIN-1-ALPHA

(Bos taurus) 		PF02210
(Laminin_G_2) 		4 ARG A1258
ILE A1098
PHE A1091
LEU A1241
 None
 0.89A 4mmcA-3asiA:
undetectable		 4mmcA-3asiA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 ILE A 531
PHE A 567
LEU A 546
THR A 994
 None
 1.07A 4mmcA-3bgaA:
undetectable		 4mmcA-3bgaA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c37 PEPTIDASE, M48
FAMILY

(Geobacter
sulfurreducens) 		PF01435
(Peptidase_M48) 		4 ARG A  83
ILE A 108
PHE A  66
LEU A  54
 None
 0.97A 4mmcA-3c37A:
undetectable		 4mmcA-3c37A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dr5 PUTATIVE
O-METHYLTRANSFERASE

(Corynebacterium
glutamicum) 		PF13578
(Methyltransf_24) 		4 ARG A 117
ILE A  63
LEU A 145
ASP A 141
 None
 0.81A 4mmcA-3dr5A:
undetectable		 4mmcA-3dr5A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwb ENDOTHELIN-CONVERTIN
G ENZYME 1

(Homo sapiens) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		4 ILE A 346
PHE A 237
LEU A 224
THR A 385
 None
 0.93A 4mmcA-3dwbA:
undetectable		 4mmcA-3dwbA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e35 UNCHARACTERIZED
PROTEIN SCO1997

(Streptomyces
coelicolor) 		PF09754
(PAC2) 		4 ARG A  63
ILE A 129
PHE A  64
LEU A 110
 None
 1.09A 4mmcA-3e35A:
undetectable		 4mmcA-3e35A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egi TRIMETHYLGUANOSINE
SYNTHASE HOMOLOG

(Homo sapiens) 		PF09445
(Methyltransf_15) 		4 ILE A 790
PHE A 698
LEU A 749
ASP A 747
 None
ADP  A   3 (-4.5A)
None
ADP  A   3 (-3.4A)
 1.07A 4mmcA-3egiA:
undetectable		 4mmcA-3egiA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fe1 HEAT SHOCK 70 KDA
PROTEIN 6

(Homo sapiens) 		PF00012
(HSP70) 		4 ILE A 333
PHE A 356
LEU A 323
ASP A 329
 None
 1.10A 4mmcA-3fe1A:
0.9		 4mmcA-3fe1A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdh TRIMETHYLGUANOSINE
SYNTHASE HOMOLOG

(Homo sapiens) 		PF09445
(Methyltransf_15) 		4 ILE A 790
PHE A 698
LEU A 749
ASP A 747
 None
SAH  A 854 (-4.3A)
SAH  A 854 ( 4.9A)
SAH  A 854 (-3.6A)
 1.10A 4mmcA-3gdhA:
undetectable		 4mmcA-3gdhA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i6v PERIPLASMIC
HIS/GLU/GLN/ARG/OPIN
E FAMILY-BINDING
PROTEIN

(Ruegeria
pomeroyi) 		PF00497
(SBP_bac_3) 		4 ILE A 258
PHE A  76
LEU A 254
THR A 131
 None
 1.10A 4mmcA-3i6vA:
undetectable		 4mmcA-3i6vA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kn3 PUTATIVE PERIPLASMIC
PROTEIN

(Wolinella
succinogenes) 		PF12849
(PBP_like_2) 		4 ILE A  85
PHE A 104
LEU A 196
ASP A 193
 None
 1.08A 4mmcA-3kn3A:
undetectable		 4mmcA-3kn3A:
18.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mpn TRANSPORTER

(Aquifex
aeolicus) 		PF00209
(SNF) 		6 ILE A 111
PHE A 320
LEU A 400
ASP A 401
ASP A 404
THR A 409
 None
 0.54A 4mmcA-3mpnA:
61.6		 4mmcA-3mpnA:
98.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mw3 NEUREXIN-2-BETA

(Rattus
norvegicus) 		PF02210
(Laminin_G_2) 		4 ARG A 288
ILE A  98
PHE A  91
LEU A 271
 None
 1.10A 4mmcA-3mw3A:
undetectable		 4mmcA-3mw3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwt NUCLEOPROTEIN

(Lassa
mammarenavirus) 		PF00843
(Arena_nucleocap)
PF17290
(Arena_ncap_C) 		4 ILE A 433
PHE A 423
LEU A 438
THR A 446
 None
 1.05A 4mmcA-3mwtA:
undetectable		 4mmcA-3mwtA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3onm TRANSCRIPTIONAL
REGULATOR LRHA

(Yersinia
pseudotuberculosis) 		PF03466
(LysR_substrate) 		4 LEU A 222
ASP A 107
ASP A 108
THR A 154
 None
 1.08A 4mmcA-3onmA:
undetectable		 4mmcA-3onmA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0w MANDELATE
RACEMASE/MUCONATE
LACTONIZING PROTEIN

(Ralstonia
pickettii) 		PF13378
(MR_MLE_C) 		4 ARG A 242
LEU A 193
ASP A 189
THR A 212
 None
 1.09A 4mmcA-3p0wA:
undetectable		 4mmcA-3p0wA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pm8 CALCIUM-DEPENDENT
PROTEIN KINASE 2

(Plasmodium
falciparum) 		PF13499
(EF-hand_7) 		4 ILE A 378
PHE A 431
LEU A 342
THR A 440
 None
 1.08A 4mmcA-3pm8A:
undetectable		 4mmcA-3pm8A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qcw NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 ARG A1332
ILE A1142
PHE A1135
LEU A1315
 None
 1.03A 4mmcA-3qcwA:
undetectable		 4mmcA-3qcwA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qn3 ENOLASE

(Campylobacter
jejuni) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 ILE A 339
PHE A 369
LEU A 133
THR A 379
 None
 0.97A 4mmcA-3qn3A:
undetectable		 4mmcA-3qn3A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5e TRANSALDOLASE

(Corynebacterium
glutamicum) 		PF00923
(TAL_FSA) 		4 ILE A 294
LEU A  16
ASP A  18
ASP A  17
 None
 1.07A 4mmcA-3r5eA:
undetectable		 4mmcA-3r5eA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ILE A 120
PHE A 372
LEU A 549
ASP A 553
 None
 0.83A 4mmcA-3s9vA:
2.4		 4mmcA-3s9vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swl CHLORIDE
INTRACELLULAR
CHANNEL PROTEIN 1

(Homo sapiens) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		4 ARG A 204
ILE A 199
ASP A 141
THR A 145
 None
 0.83A 4mmcA-3swlA:
undetectable		 4mmcA-3swlA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1e HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 ILE A 226
LEU A 228
ASP A 230
ASP A 229
 None
 1.10A 4mmcA-3t1eA:
undetectable		 4mmcA-3t1eA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6q CD180 ANTIGEN

(Mus musculus) 		PF13855
(LRR_8) 		4 ILE A  68
PHE A  97
LEU A  84
THR A 135
 None
 0.99A 4mmcA-3t6qA:
undetectable		 4mmcA-3t6qA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8l ADENINE DEAMINASE 2

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1)
PF13382
(Adenine_deam_C) 		4 ILE A  54
LEU A  41
ASP A  43
THR A 324
 None
 1.05A 4mmcA-3t8lA:
undetectable		 4mmcA-3t8lA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ab5 TRANSCRIPTIONAL
REGULATOR, LYSR
FAMILY

(Neisseria
meningitidis) 		PF03466
(LysR_substrate) 		4 ARG A 295
ILE A  99
PHE A 288
LEU A 126
 None
 1.04A 4mmcA-4ab5A:
undetectable		 4mmcA-4ab5A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ay9 FOLLICLE-STIMULATING
HORMONE RECEPTOR

(Homo sapiens) 		PF01462
(LRRNT)
PF12369
(GnHR_trans)
PF13306
(LRR_5) 		4 ILE X 160
PHE X 190
LEU X 177
THR X 228
 None
 1.04A 4mmcA-4ay9X:
undetectable		 4mmcA-4ay9X:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bjp PENICILLIN BINDING
PROTEIN
TRANSPEPTIDASE
DOMAIN PROTEIN

(Escherichia
coli) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 ARG A 430
ILE A 446
LEU A 393
THR A 424
 None
 1.06A 4mmcA-4bjpA:
undetectable		 4mmcA-4bjpA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgv CHROMOSOME REGION
MAINTENANCE 1 (CRM1)
OR EXPORTIN 1 (XPO1)

(Chaetomium
thermophilum) 		PF03810
(IBN_N)
PF08389
(Xpo1)
PF08767
(CRM1_C) 		4 ILE A 498
LEU A 477
ASP A 520
THR A 525
 None
 1.06A 4mmcA-4fgvA:
undetectable		 4mmcA-4fgvA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzh HEMAGGLUTININ-NEURAM
INIDASE

(Avian
avulavirus 1) 		PF00423
(HN) 		4 ILE A 227
LEU A 229
ASP A 231
ASP A 230
 None
 1.04A 4mmcA-4fzhA:
undetectable		 4mmcA-4fzhA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fzv PUTATIVE
METHYLTRANSFERASE
NSUN4

(Homo sapiens) 		PF01189
(Methyltr_RsmB-F) 		4 ILE A  63
LEU A  67
ASP A 261
THR A 259
 None
 1.08A 4mmcA-4fzvA:
undetectable		 4mmcA-4fzvA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hep VHH17 DOMAIN

(Lama glama) 		PF07686
(V-set) 		4 ARG G 100
ILE G  34
PHE G  27
LEU G   4
 None
 0.94A 4mmcA-4hepG:
undetectable		 4mmcA-4hepG:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hw9 MECHANOSENSITIVE
CHANNEL MSCS

(Helicobacter
pylori) 		PF00924
(MS_channel) 		4 ARG A 174
ILE A 204
LEU A 243
THR A 225
 None
 1.08A 4mmcA-4hw9A:
2.9		 4mmcA-4hw9A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhj MIF4G
DOMAIN-CONTAINING
PROTEIN B

(Danio rerio) 		PF02854
(MIF4G) 		4 ARG A  57
ILE A  41
PHE A  51
LEU A  22
 None
 0.89A 4mmcA-4jhjA:
undetectable		 4mmcA-4jhjA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		4 ARG A 428
ILE A 442
PHE A 460
LEU A 389
 None
 0.94A 4mmcA-4lglA:
0.0		 4mmcA-4lglA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nen INTEGRIN ALPHA-X

(Homo sapiens) 		PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ILE A 553
PHE A 565
LEU A 594
THR A 507
 None
 1.02A 4mmcA-4nenA:
undetectable		 4mmcA-4nenA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nu3 ICE-BINDING PROTEIN

(Flavobacterium
frigoris) 		PF11999
(DUF3494) 		4 ILE A  54
PHE A  79
LEU A 247
THR A 253
 None
 0.98A 4mmcA-4nu3A:
undetectable		 4mmcA-4nu3A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oja SUPEROXIDE DISMUTASE
[CU-ZN]

(Hydra vulgaris) 		PF00080
(Sod_Cu) 		4 ILE A  17
PHE A  44
LEU A   9
THR A  59
 None
 1.06A 4mmcA-4ojaA:
undetectable		 4mmcA-4ojaA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ote LIPOPROTEIN

(Clostridioides
difficile) 		PF03180
(Lipoprotein_9) 		4 ILE A 130
PHE A 124
LEU A 146
THR A 214
 None
 1.10A 4mmcA-4oteA:
undetectable		 4mmcA-4oteA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4h HIV-1 ENV GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 ILE A 345
PHE A 360
LEU A 349
THR A 283
 None
 1.11A 4mmcA-4r4hA:
undetectable		 4mmcA-4r4hA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
TER94

(Drosophila
melanogaster) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 ILE A 113
PHE A 136
ASP A 147
THR A  64
 None
 1.11A 4mmcA-4rv0A:
undetectable		 4mmcA-4rv0A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rwt LEIOMODIN-2

(Homo sapiens) 		no annotation 4 ARG C 270
ILE C 256
LEU C 232
THR C 212
 None
 1.04A 4mmcA-4rwtC:
undetectable		 4mmcA-4rwtC:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xn3 TAIL SPIKE PROTEIN

(Salmonella
virus HK620) 		no annotation 4 ILE A 230
PHE A 244
LEU A 176
THR A 190
 None
 1.09A 4mmcA-4xn3A:
undetectable		 4mmcA-4xn3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xox 3-OXOACYL-ACP
SYNTHASE

(Vibrio cholerae) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 ILE A 370
LEU A 307
ASP A 303
THR A 299
 None
 0.79A 4mmcA-4xoxA:
undetectable		 4mmcA-4xoxA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ze8 ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN
(AGROCINOPINES A AND
B)

(Agrobacterium
fabrum) 		PF00496
(SBP_bac_5) 		4 ARG A 416
ILE A 367
PHE A 297
LEU A 306
 GOL  A 606 (-3.6A)
None
None
None
 1.08A 4mmcA-4ze8A:
undetectable		 4mmcA-4ze8A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgc KELCH PROTEIN

(Plasmodium
falciparum) 		PF01344
(Kelch_1)
PF02214
(BTB_2)
PF13418
(Kelch_4) 		4 ARG A 404
ILE A 354
PHE A 403
LEU A 368
 None
 1.07A 4mmcA-4zgcA:
undetectable		 4mmcA-4zgcA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5afu DYNACTIN

(Sus scrofa) 		PF00022
(Actin) 		4 ARG A 123
ILE A 371
LEU A 137
THR A 131
 None
 0.92A 4mmcA-5afuA:
undetectable		 4mmcA-5afuA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c05 PUTATIVE
GAMMA-TERPINENE
SYNTHASE

(Thymus vulgaris) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ILE A  92
PHE A 124
LEU A 276
ASP A 280
 ILE  A  92 ( 0.6A)
PHE  A 124 ( 1.3A)
LEU  A 276 ( 0.6A)
ASP  A 280 ( 0.5A)
 0.82A 4mmcA-5c05A:
undetectable		 4mmcA-5c05A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d62 AGGLUTININ

(Marasmius
oreades) 		PF14200
(RicinB_lectin_2) 		4 ARG A 155
ILE A 102
PHE A 153
LEU A  62
 None
 1.10A 4mmcA-5d62A:
undetectable		 4mmcA-5d62A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6a PREDICTED ATPASE OF
THE ABC CLASS

(Vibrio
vulnificus) 		PF09818
(ABC_ATPase) 		4 ARG A 117
ILE A 146
PHE A 118
LEU A  33
 None
 1.08A 4mmcA-5d6aA:
undetectable		 4mmcA-5d6aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dpw MICROTUBULE-ASSOCIAT
ED PROTEINS 1A/1B
LIGHT CHAIN 3C

(Homo sapiens) 		PF02991
(Atg8) 		4 ILE A  63
PHE A  48
LEU A  43
ASP A  44
 None
 1.04A 4mmcA-5dpwA:
undetectable		 4mmcA-5dpwA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3t PHOSPHATIDYLINOSITOL
-4-PHOSPHATE
5-KINASE, TYPE I,
ALPHA

(Danio rerio) 		PF01504
(PIP5K) 		4 ILE A 379
LEU A 292
ASP A 288
THR A 284
 None
 1.01A 4mmcA-5e3tA:
undetectable		 4mmcA-5e3tA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e6s INTEGRIN ALPHA-L

(Homo sapiens) 		PF00092
(VWA)
PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 ILE A 544
PHE A 556
LEU A 585
THR A 501
 None
 1.07A 4mmcA-5e6sA:
undetectable		 4mmcA-5e6sA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5elp NRPS/PKS PROTEIN

(Bacillus
amyloliquefaciens) 		no annotation 4 ILE C 348
LEU C 329
ASP C 325
THR C 321
 None
 0.96A 4mmcA-5elpC:
undetectable		 4mmcA-5elpC:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ezr CGMP-DEPENDENT
PROTEIN KINASE,
PUTATIVE

(Plasmodium
vivax) 		PF00027
(cNMP_binding)
PF00069
(Pkinase) 		4 ILE A 397
PHE A 292
LEU A 388
THR A 380
 None
 0.98A 4mmcA-5ezrA:
undetectable		 4mmcA-5ezrA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT ETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		4 ILE h 292
PHE h 365
LEU h 294
THR h 223
 None
 1.00A 4mmcA-5gw5h:
1.2		 4mmcA-5gw5h:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ht0 AMINOGLYCOSIDE
ACETYLTRANSFERASE
HMB0005

(uncultured
bacterium) 		PF02522
(Antibiotic_NAT) 		4 ILE A 121
LEU A  46
ASP A  43
ASP A  47
 None
 1.02A 4mmcA-5ht0A:
undetectable		 4mmcA-5ht0A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 ARG A 878
ILE A 658
PHE A  18
ASP A 600
 None
 0.78A 4mmcA-5kf7A:
1.0		 4mmcA-5kf7A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lkd GLUTATHIONE
S-TRANSFERASE
OMEGA-LIKE 2

(Saccharomyces
cerevisiae) 		PF13409
(GST_N_2)
PF13410
(GST_C_2) 		4 ILE A  65
PHE A 186
LEU A 161
THR A 166
 None
 0.95A 4mmcA-5lkdA:
undetectable		 4mmcA-5lkdA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m60 BETA-1,3-GLUCANASE

(Chaetomium
thermophilum) 		PF12708
(Pectate_lyase_3) 		4 PHE A 647
LEU A 297
ASP A 298
ASP A 326
 None
 1.07A 4mmcA-5m60A:
undetectable		 4mmcA-5m60A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n1t FLAVIN-BINDING
SUBUNIT OF SULFIDE
DEHYDROGENASE

(Thioalkalivibrio
paradoxus) 		no annotation 4 ILE A  64
LEU A 121
ASP A 123
ASP A 122
 None
 1.11A 4mmcA-5n1tA:
undetectable		 4mmcA-5n1tA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sva MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 21
MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 7

(Saccharomyces
cerevisiae) 		PF05983
(Med7)
PF11221
(Med21) 		4 ARG U 152
ILE U 158
LEU W  12
ASP W  13
 None
 0.87A 4mmcA-5svaU:
3.2		 4mmcA-5svaU:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szp PROTOCADHERIN GAMMA
B7

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 ILE A 200
PHE A 148
LEU A 170
ASP A 116
 None
 0.79A 4mmcA-5szpA:
undetectable		 4mmcA-5szpA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vni PROTEIN TRANSPORT
PROTEIN SEC23A

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 ARG A 262
ILE A 347
LEU A 357
ASP A 598
 None
 1.08A 4mmcA-5vniA:
undetectable		 4mmcA-5vniA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wgx FLAVIN-DEPENDENT
HALOGENASE

(Malbranchea
aurantiaca) 		PF04820
(Trp_halogenase) 		4 ILE A 429
LEU A 449
ASP A 453
THR A 418
 None
 0.94A 4mmcA-5wgxA:
undetectable		 4mmcA-5wgxA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wjm CADHERIN-23

(Mus musculus) 		no annotation 4 ARG A1779
ILE A1816
PHE A1769
LEU A1786
 None
 1.12A 4mmcA-5wjmA:
undetectable		 4mmcA-5wjmA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xxo PERIPLASMIC
BETA-GLUCOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 ARG A 767
ILE A 731
PHE A 768
LEU A 736
 None
 1.07A 4mmcA-5xxoA:
undetectable		 4mmcA-5xxoA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3j TOLL-LIKE RECEPTOR 9

(Equus caballus) 		no annotation 4 ARG A 738
ILE A 801
PHE A 770
LEU A 806
 None
 1.06A 4mmcA-5y3jA:
undetectable		 4mmcA-5y3jA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ydf PARAFIBROMIN

(Homo sapiens) 		no annotation 4 ILE A  60
LEU A  94
ASP A  93
ASP A  90
 None
 1.06A 4mmcA-5ydfA:
undetectable		 4mmcA-5ydfA:
9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yll BETA-1,4-MANNANASE

(Amphibacillus
xylanus) 		no annotation 4 ARG B 309
ILE B 302
PHE B 258
LEU B 272
 None
 0.98A 4mmcA-5yllB:
undetectable		 4mmcA-5yllB:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zq6 SIDE

(Legionella
pneumophila) 		no annotation 4 ILE A 610
PHE A 634
LEU A 738
THR A 668
 None
 1.03A 4mmcA-5zq6A:
undetectable		 4mmcA-5zq6A:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6blj SERINE-TRNA LIGASE

(Naegleria
fowleri) 		no annotation 4 ARG A   8
ILE A  18
LEU A   2
ASP A   3
 None
 0.99A 4mmcA-6bljA:
1.2		 4mmcA-6bljA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d5i PHOSPHOENOLPYRUVATE
CARBOXYKINASE (ATP)

(Escherichia
coli) 		no annotation 4 PHE A 517
LEU A 368
ASP A 363
THR A 252
 None
None
None
ATP  A 601 (-4.4A)
 1.05A 4mmcA-6d5iA:
undetectable		 4mmcA-6d5iA:
11.96