SIMILAR PATTERNS OF AMINO ACIDS FOR 4MJ8_C_SPMC201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ajz DIHYDROPTEROATE
SYNTHASE

(Escherichia
coli) 		PF00809
(Pterin_bind) 		4 ASN A 162
GLU A 167
TYR A 164
GLU A 160
 None
 1.18A 4mj8C-1ajzA:
0.8		 4mj8C-1ajzA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bik BIKUNIN

(Homo sapiens) 		PF00014
(Kunitz_BPTI) 		4 ASN A  45
GLU A  69
TYR A  42
GLU A  52
 NAG  A 148 (-1.7A)
None
None
NAG  A 148 ( 4.0A)
 1.30A 4mj8C-1bikA:
undetectable		 4mj8C-1bikA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 ASN A 514
GLU A 519
TYR A 428
GLU A 431
 None
 1.16A 4mj8C-1c2oA:
1.4		 4mj8C-1c2oA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c7t BETA-N-ACETYLHEXOSAM
INIDASE

(Serratia
marcescens) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF03173
(CHB_HEX)
PF03174
(CHB_HEX_C) 		5 ASN A 719
GLU A 782
GLU A 708
TYR A 778
GLU A 777
 None
 1.43A 4mj8C-1c7tA:
0.0		 4mj8C-1c7tA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h14 ENDO-1,4-BETA-XYLANA
SE

(Pseudoalteromonas
haloplanktis) 		PF01270
(Glyco_hydro_8) 		4 MET A 175
GLU A 146
GLU A 147
TYR A 148
 None
 1.22A 4mj8C-1h14A:
0.0		 4mj8C-1h14A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibq ASPERGILLOPEPSIN

(Aspergillus
phoenicis) 		PF00026
(Asp) 		4 ASN A 117
GLU A 110
GLU A  15
GLU A  14
 None
 1.23A 4mj8C-1ibqA:
0.0		 4mj8C-1ibqA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ifg ECOTIN

(Escherichia
coli) 		PF03974
(Ecotin) 		4 MET A 106
GLU A  39
TYR A 109
GLU A 133
 None
 1.09A 4mj8C-1ifgA:
undetectable		 4mj8C-1ifgA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jba PROTEIN (GUANYLATE
CYCLASE ACTIVATING
PROTEIN 2)

(Bos taurus) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		4 ASN A  13
GLU A   9
GLU A  11
GLU A  12
 None
 1.26A 4mj8C-1jbaA:
0.0		 4mj8C-1jbaA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m53 ISOMALTULOSE
SYNTHASE

(Klebsiella sp.
LX3) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 ASN A 503
GLU A 495
GLU A 410
TYR A 505
 None
 1.15A 4mj8C-1m53A:
0.0		 4mj8C-1m53A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qp8 FORMATE
DEHYDROGENASE

(Pyrobaculum
aerophilum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 MET A 276
GLU A  12
GLU A  14
GLU A  15
 None
 1.21A 4mj8C-1qp8A:
undetectable		 4mj8C-1qp8A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rh1 COLICIN B

(Escherichia
coli) 		PF01024
(Colicin)
PF03515
(Cloacin) 		4 ASN A 303
GLU A 299
GLU A 301
TYR A 259
 None
 1.11A 4mj8C-1rh1A:
undetectable		 4mj8C-1rh1A:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rz3 HYPOTHETICAL PROTEIN
RBSTP0775

(Geobacillus
stearothermophilus) 		PF00485
(PRK) 		4 ASN A  73
GLU A  74
GLU A  75
TYR A  69
 None
 1.37A 4mj8C-1rz3A:
undetectable		 4mj8C-1rz3A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc6 BETA-GALACTOSIDASE

(Penicillium sp.) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 ASN A 321
GLU A 378
GLU A 382
GLU A 323
 None
MAN  A3005 (-2.9A)
None
MAN  A3007 (-3.5A)
 1.35A 4mj8C-1xc6A:
undetectable		 4mj8C-1xc6A:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z27 OOKINETE SURFACE
PROTEIN PVS25

(Plasmodium
vivax) 		PF06247
(Plasmod_Pvs28) 		4 ASN A  40
GLU A  41
TYR A  69
GLU A  45
 None
 1.23A 4mj8C-1z27A:
undetectable		 4mj8C-1z27A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zl9 GLUTATHIONE
S-TRANSFERASE 5

(Caenorhabditis
elegans) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 ASN A  32
GLU A  57
TYR A  29
GLU A  30
 None
 1.19A 4mj8C-1zl9A:
undetectable		 4mj8C-1zl9A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cpt VACUOLAR SORTING
PROTEIN 4B

(Homo sapiens) 		PF04212
(MIT) 		4 ASN A  33
GLU A  35
TYR A  41
GLU A  28
 None
 1.26A 4mj8C-2cptA:
undetectable		 4mj8C-2cptA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4w GLYCEROL KINASE

(Cellulomonas
sp.) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 MET A 476
GLU A 480
GLU A 482
TYR A 485
 None
 1.21A 4mj8C-2d4wA:
undetectable		 4mj8C-2d4wA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5w PEPTIDE ABC
TRANSPORTER,
PEPTIDE-BINDING
PROTEIN

(Thermus
thermophilus) 		PF00496
(SBP_bac_5) 		4 ASN A 508
GLU A 510
GLU A 541
GLU A 540
 None
 1.35A 4mj8C-2d5wA:
undetectable		 4mj8C-2d5wA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d9j REGULATOR OF
G-PROTEIN SIGNALLING
7

(Homo sapiens) 		PF00615
(RGS) 		4 ASN A  44
GLU A  39
GLU A  37
GLU A  43
 None
 1.34A 4mj8C-2d9jA:
undetectable		 4mj8C-2d9jA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9i F420-0:GAMMA-GLUTAMY
L LIGASE

(Archaeoglobus
fulgidus) 		PF01996
(F420_ligase) 		4 ASN A  57
GLU A  74
GLU A  55
GLU A  81
 None
 1.31A 4mj8C-2g9iA:
undetectable		 4mj8C-2g9iA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 GLU A 198
GLU A 241
GLU A 202
GLU A 119
 None
 0.99A 4mj8C-2gp6A:
undetectable		 4mj8C-2gp6A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mct UNCHARACTERIZED
PROTEIN

([Ruminococcus]
gnavus) 		PF17225
(DUF5301) 		4 GLU A  77
TYR A  59
GLU A  58
GLU A  57
 None
 1.08A 4mj8C-2mctA:
undetectable		 4mj8C-2mctA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mk6 ADAPTER PROTEIN MECA

(Bacillus
subtilis) 		PF05389
(MecA) 		4 GLU A   4
GLU A  72
TYR A  14
GLU A   2
 None
 1.02A 4mj8C-2mk6A:
undetectable		 4mj8C-2mk6A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nck NUCLEOSIDE
DIPHOSPHATE KINASE

(Myxococcus
xanthus) 		no annotation 4 ASN R  81
GLU R  80
GLU R  78
GLU R   4
 None
 1.30A 4mj8C-2nckR:
undetectable		 4mj8C-2nckR:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nlx XYLULOSE KINASE

(Escherichia
coli) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASN A 121
MET A 175
GLU A 109
GLU A 271
 None
 1.36A 4mj8C-2nlxA:
undetectable		 4mj8C-2nlxA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pun METHYLTHIORIBOSE
KINASE

(Bacillus
subtilis) 		PF01636
(APH) 		4 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 0.98A 4mj8C-2punA:
undetectable		 4mj8C-2punA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r66 GLYCOSYL
TRANSFERASE, GROUP 1

(Halothermothrix
orenii) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		4 ASN A 112
GLU A 116
GLU A 117
GLU A  71
 None
 1.36A 4mj8C-2r66A:
undetectable		 4mj8C-2r66A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vqr PUTATIVE SULFATASE

(Rhizobium
leguminosarum) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 ASN A 341
MET A 255
GLU A 248
GLU A 466
 None
 1.35A 4mj8C-2vqrA:
undetectable		 4mj8C-2vqrA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wa0 MELANOMA-ASSOCIATED
ANTIGEN 4

(Homo sapiens) 		PF01454
(MAGE) 		4 GLU A 221
GLU A 219
TYR A 270
GLU A 271
 None
 1.13A 4mj8C-2wa0A:
undetectable		 4mj8C-2wa0A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wsm HYDROGENASE
EXPRESSION/FORMATION
PROTEIN (HYPB)

(Archaeoglobus
fulgidus) 		PF02492
(cobW) 		4 ASN A  34
MET A  36
TYR A 132
GLU A 130
 None
 1.26A 4mj8C-2wsmA:
undetectable		 4mj8C-2wsmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E2 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF00943
(Alpha_E2_glycop) 		4 ASN B 363
GLU B 388
GLU B 366
GLU B 367
 None
 1.20A 4mj8C-2xfbB:
undetectable		 4mj8C-2xfbB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xts SULFITE
DEHYDROGENASE

(Paracoccus
pantotrophus) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 MET A 262
GLU A 259
GLU A 281
GLU A 282
 None
CO  A1431 (-2.6A)
None
None
 1.25A 4mj8C-2xtsA:
undetectable		 4mj8C-2xtsA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xy9 ANGIOTENSIN-CONVERTI
NG ENZYME

(Homo sapiens) 		PF01401
(Peptidase_M2) 		4 ASN A 246
GLU A 608
GLU A 606
TYR A 250
 None
 1.30A 4mj8C-2xy9A:
undetectable		 4mj8C-2xy9A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y0o PROBABLE D-LYXOSE
KETOL-ISOMERASE

(Bacillus
subtilis) 		no annotation 4 ASN A   9
GLU A   6
GLU A   7
TYR A  11
 None
 1.36A 4mj8C-2y0oA:
undetectable		 4mj8C-2y0oA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yoc PULLULANASE

(Klebsiella
oxytoca) 		PF02922
(CBM_48)
PF03714
(PUD)
PF11852
(DUF3372) 		4 GLU A 475
GLU A 377
TYR A 378
GLU A 564
 CA  A2071 (-3.0A)
None
None
None
 1.36A 4mj8C-2yocA:
undetectable		 4mj8C-2yocA:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yv2 SUCCINYL-COA
SYNTHETASE ALPHA
CHAIN

(Aeropyrum
pernix) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		4 GLU A 279
TYR A 240
GLU A 286
GLU A 282
 None
 1.31A 4mj8C-2yv2A:
undetectable		 4mj8C-2yv2A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yvt HYPOTHETICAL PROTEIN
AQ_1956

(Aquifex
aeolicus) 		PF14582
(Metallophos_3) 		4 ASN A  99
GLU A 149
GLU A  49
GLU A  53
 None
 1.11A 4mj8C-2yvtA:
2.1		 4mj8C-2yvtA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyy GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Methanocaldococcus
jannaschii) 		PF01113
(DapB_N)
PF02800
(Gp_dh_C) 		4 ASN A  97
GLU A 115
TYR A 138
GLU A  99
 NAP  A2001 (-3.3A)
None
None
None
 1.21A 4mj8C-2yyyA:
undetectable		 4mj8C-2yyyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z13 EF-HAND
DOMAIN-CONTAINING
FAMILY MEMBER C2

(Homo sapiens) 		PF06565
(DUF1126) 		4 GLU A  24
TYR A  38
GLU A  54
GLU A  56
 None
 1.33A 4mj8C-2z13A:
undetectable		 4mj8C-2z13A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z61 PROBABLE ASPARTATE
AMINOTRANSFERASE 2

(Methanocaldococcus
jannaschii) 		PF00155
(Aminotran_1_2) 		4 ASN A 356
GLU A 281
TYR A 354
GLU A 355
 None
 1.03A 4mj8C-2z61A:
undetectable		 4mj8C-2z61A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zxx GEMININ

(Mus musculus) 		PF07412
(Geminin) 		4 ASN A 114
GLU A 113
GLU A 109
TYR A 108
 None
 1.27A 4mj8C-2zxxA:
undetectable		 4mj8C-2zxxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1y 50S RIBOSOMAL
PROTEIN P1 (L12P)

(Pyrococcus
horikoshii) 		PF00428
(Ribosomal_60s) 		4 ASN A  21
GLU A  16
GLU A  19
GLU A  20
 None
 1.13A 4mj8C-3a1yA:
undetectable		 4mj8C-3a1yA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c37 PEPTIDASE, M48
FAMILY

(Geobacter
sulfurreducens) 		PF01435
(Peptidase_M48) 		4 ASN A 109
GLU A 162
TYR A 157
GLU A 107
 None
ZN  A 301 (-2.2A)
None
None
 1.08A 4mj8C-3c37A:
undetectable		 4mj8C-3c37A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evz METHYLTRANSFERASE

(Pyrococcus
furiosus) 		PF05175
(MTS) 		4 ASN A 123
GLU A  57
GLU A 118
GLU A 125
 None
 1.14A 4mj8C-3evzA:
3.1		 4mj8C-3evzA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f3k UNCHARACTERIZED
PROTEIN YKR043C

(Saccharomyces
cerevisiae) 		PF00300
(His_Phos_1) 		4 GLU A 106
GLU A  99
GLU A 101
GLU A 139
 None
 1.33A 4mj8C-3f3kA:
undetectable		 4mj8C-3f3kA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fve DIAMINOPIMELATE
EPIMERASE

(Mycobacterium
tuberculosis) 		PF01678
(DAP_epimerase) 		4 ASN A 199
GLU A 217
GLU A 222
GLU A 201
 None
 1.34A 4mj8C-3fveA:
undetectable		 4mj8C-3fveA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g65 CHECKPOINT PROTEIN
HUS1

(Homo sapiens) 		PF04005
(Hus1) 		4 ASN C 191
GLU C 195
GLU C 183
GLU C 229
 None
 1.09A 4mj8C-3g65C:
undetectable		 4mj8C-3g65C:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hr8 PROTEIN RECA

(Thermotoga
maritima) 		PF00154
(RecA) 		4 ASN A 195
GLU A 209
GLU A 226
GLU A  65
 None
 1.02A 4mj8C-3hr8A:
undetectable		 4mj8C-3hr8A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3juj UDP-GLUCOSE
PYROPHOSPHORYLASE
(GALU)

(Helicobacter
pylori) 		PF00483
(NTP_transferase) 		4 ASN A 200
GLU A 166
TYR A 170
GLU A 160
 None
 1.28A 4mj8C-3jujA:
undetectable		 4mj8C-3jujA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kf6 PROTEIN STN1

(Schizosaccharomyces
pombe) 		PF10451
(Stn1) 		4 MET A  97
GLU A 125
TYR A  55
GLU A 132
 None
 1.29A 4mj8C-3kf6A:
undetectable		 4mj8C-3kf6A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ki6 CHOLIX TOXIN

(Vibrio cholerae) 		PF09009
(Exotox-A_cataly) 		4 ASN A 602
GLU A 605
TYR A 604
GLU A 606
 None
 1.37A 4mj8C-3ki6A:
undetectable		 4mj8C-3ki6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyf PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pseudomonas
putida) 		PF07238
(PilZ)
PF07317
(YcgR) 		4 ASN A 170
GLU A 206
GLU A 205
GLU A 172
 None
 1.25A 4mj8C-3kyfA:
undetectable		 4mj8C-3kyfA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkq COATOMER
BETA'-SUBUNIT

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF04053
(Coatomer_WDAD) 		4 ASN A 621
GLU A 605
GLU A 617
GLU A 614
 None
 1.24A 4mj8C-3mkqA:
undetectable		 4mj8C-3mkqA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n40 P62 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF00943
(Alpha_E2_glycop)
PF01563
(Alpha_E3_glycop) 		4 ASN P 363
GLU P 388
GLU P 366
GLU P 367
 None
 1.22A 4mj8C-3n40P:
undetectable		 4mj8C-3n40P:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o0y LIPOPROTEIN

(Colwellia
psychrerythraea) 		PF05960
(DUF885) 		4 ASN A 441
MET A 374
GLU A 369
TYR A 366
 None
 1.31A 4mj8C-3o0yA:
undetectable		 4mj8C-3o0yA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogr BETA-GALACTOSIDASE

(Trichoderma
reesei) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1031 (-3.9A)
MAN  A1028 (-2.7A)
None
MAN  A1029 (-3.5A)
 1.30A 4mj8C-3ogrA:
undetectable		 4mj8C-3ogrA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oz7 PHOSPHOGLYCERATE
KINASE

(Plasmodium
falciparum) 		PF00162
(PGK) 		4 ASN A 356
GLU A 360
TYR A 323
GLU A 353
 None
 1.01A 4mj8C-3oz7A:
undetectable		 4mj8C-3oz7A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p1u SUSD HOMOLOG

(Parabacteroides
distasonis) 		PF12741
(SusD-like) 		4 ASN A 518
GLU A 521
GLU A 523
GLU A 514
 None
 1.34A 4mj8C-3p1uA:
undetectable		 4mj8C-3p1uA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qqz PUTATIVE
UNCHARACTERIZED
PROTEIN YJIK

(Escherichia
coli) 		PF06977
(SdiA-regulated) 		4 ASN A 114
GLU A 310
GLU A 141
GLU A 192
 None
CA  A 325 ( 4.9A)
CA  A 325 ( 2.4A)
CA  A 326 (-2.2A)
 1.37A 4mj8C-3qqzA:
undetectable		 4mj8C-3qqzA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdq ALPHA-BISABOLENE
SYNTHASE

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		4 ASN A 488
MET A  66
GLU A  62
GLU A 493
 None
 1.20A 4mj8C-3sdqA:
undetectable		 4mj8C-3sdqA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		4 ASN A 333
MET A 313
GLU A 512
GLU A 332
 None
 1.24A 4mj8C-3srzA:
undetectable		 4mj8C-3srzA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wh9 ENDO-BETA-1,4-MANNAN
ASE

(Aspergillus
niger) 		PF00150
(Cellulase) 		4 GLU A 164
TYR A 111
GLU A 168
GLU A 204
 None
None
TRS  A 404 (-2.9A)
None
 1.27A 4mj8C-3wh9A:
undetectable		 4mj8C-3wh9A:
18.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3wr7 SPERMIDINE
N1-ACETYLTRANSFERASE

(Escherichia
coli) 		PF13302
(Acetyltransf_3) 		6 MET A  28
GLU A  33
GLU A  34
TYR A  36
GLU A  37
GLU A  41
 None
SPD  A 201 (-3.9A)
SPD  A 201 (-4.0A)
SPD  A 201 (-4.6A)
None
SPD  A 201 (-3.1A)
 0.64A 4mj8C-3wr7A:
28.7		 4mj8C-3wr7A:
57.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ziz GH5
ENDO-BETA-1,4-MANNAN
ASE

(Podospora
anserina) 		PF00150
(Cellulase) 		4 GLU A 165
TYR A 113
GLU A 169
GLU A 205
 None
None
TRS  A1352 (-2.8A)
None
 1.21A 4mj8C-3zizA:
undetectable		 4mj8C-3zizA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amf PHOX

(Pseudomonas
fluorescens) 		PF05787
(DUF839) 		4 ASN A  68
GLU A  90
TYR A  91
GLU A 532
 None
FEO  A1595 ( 2.6A)
None
CA  A1594 (-2.3A)
 1.28A 4mj8C-4amfA:
undetectable		 4mj8C-4amfA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fvs PUTATIVE LIPOPROTEIN

(Parabacteroides
distasonis) 		no annotation 4 GLU A  67
GLU A  65
TYR A  88
GLU A 119
 None
 1.08A 4mj8C-4fvsA:
undetectable		 4mj8C-4fvsA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4he4 YELLOW FLUORESCENT
PROTEIN

(Phialidium sp.
SL-2003) 		PF01353
(GFP) 		4 ASN A 119
GLU A 113
TYR A 118
GLU A  17
 CRO  A  65 ( 4.0A)
None
None
None
 1.32A 4mj8C-4he4A:
undetectable		 4mj8C-4he4A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jn6 4-HYDROXY-2-OXOVALER
ATE ALDOLASE

(Mycobacterium
tuberculosis) 		PF00682
(HMGL-like)
PF07836
(DmpG_comm) 		4 ASN A 103
GLU A  69
GLU A  67
GLU A  99
 None
 1.33A 4mj8C-4jn6A:
0.6		 4mj8C-4jn6A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxr PPE41

(Mycobacterium
tuberculosis) 		PF00823
(PPE) 		4 ASN B  11
MET B 103
GLU B 148
GLU B   4
 None
 1.16A 4mj8C-4kxrB:
undetectable		 4mj8C-4kxrB:
23.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4mi4 SPERMIDINE
N1-ACETYLTRANSFERASE

(Vibrio cholerae) 		PF13302
(Acetyltransf_3) 		7 ASN A  22
MET A  28
GLU A  33
GLU A  34
TYR A  36
GLU A  37
GLU A  41
 SPM  A 201 (-3.7A)
SPM  A 201 ( 4.5A)
SPM  A 201 (-3.2A)
SPM  A 201 (-4.1A)
SPM  A 201 (-4.7A)
SPM  A 201 (-3.5A)
SPM  A 201 (-2.8A)
 0.41A 4mj8C-4mi4A:
30.9		 4mj8C-4mi4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mnu SLYA-LIKE
TRANSCRIPTION
REGULATOR

(Listeria
monocytogenes) 		PF01047
(MarR) 		4 ASN A 105
TYR A 107
GLU A 104
GLU A  22
 None
 1.15A 4mj8C-4mnuA:
undetectable		 4mj8C-4mnuA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qan HYPOTHETICAL PROTEIN

([Ruminococcus]
gnavus) 		no annotation 4 GLU A 175
GLU A 152
GLU A 173
GLU A 159
 None
 1.19A 4mj8C-4qanA:
undetectable		 4mj8C-4qanA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgk FATTY ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		4 ASN A 164
GLU A 141
GLU A 138
GLU A 169
 None
 1.26A 4mj8C-4qgkA:
undetectable		 4mj8C-4qgkA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qts CRISPR TYPE
III-ASSOCIATED RAMP
PROTEIN CSM3
CRISPR TYPE
III-ASSOCIATED RAMP
PROTEIN CSM4

(Methanocaldococcus
jannaschii) 		PF03787
(RAMPs) 		4 GLU A 229
GLU A 245
GLU C 160
GLU C  13
 None
 1.14A 4mj8C-4qtsA:
undetectable		 4mj8C-4qtsA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4quf RE36324P

(Drosophila
melanogaster) 		PF00385
(Chromo) 		4 ASN A  63
TYR A  24
GLU A  23
GLU A  22
 None
 1.27A 4mj8C-4qufA:
undetectable		 4mj8C-4qufA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgp CSM6_III-A

(Streptococcus
mutans) 		PF09659
(Cas_Csm6) 		4 ASN A  72
GLU A  75
TYR A  74
GLU A  77
 None
 1.11A 4mj8C-4rgpA:
undetectable		 4mj8C-4rgpA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s1v D-3-PHOSPHOGLYCERATE
DEHYDROGENASE-RELATE
D PROTEIN

(Vibrio cholerae) 		no annotation 4 GLU D 274
GLU D 267
GLU D 265
GLU D 240
 None
 1.24A 4mj8C-4s1vD:
undetectable		 4mj8C-4s1vD:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uxv SEPTATION RING
FORMATION REGULATOR
EZRA

(Bacillus
subtilis) 		PF06160
(EzrA) 		4 ASN A 404
GLU A 411
GLU A 337
GLU A 345
 None
 1.22A 4mj8C-4uxvA:
undetectable		 4mj8C-4uxvA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpg DTDP-4-DEHYDRORHAMNO
SE REDUCTASE

(Streptococcus
pyogenes) 		PF04321
(RmlD_sub_bind) 		4 GLU A 193
GLU A  14
TYR A  17
GLU A  21
 None
 1.02A 4mj8C-4wpgA:
undetectable		 4mj8C-4wpgA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xul MG662

(Megavirus
chiliensis) 		no annotation 4 ASN A  76
GLU A  75
GLU A 187
TYR A  78
 None
 1.21A 4mj8C-4xulA:
undetectable		 4mj8C-4xulA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 ASN A 988
GLU A 985
GLU A 983
GLU A1161
 None
 1.35A 4mj8C-4yswA:
1.8		 4mj8C-4yswA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5doo PROTEIN LYSINE
METHYLTRANSFERASE 2

(Rickettsia
typhi) 		PF10119
(MethyTransf_Reg)
PF13847
(Methyltransf_31) 		4 ASN A 368
GLU A 381
TYR A 363
GLU A 367
 None
 1.19A 4mj8C-5dooA:
1.8		 4mj8C-5dooA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dz2 GERMACRADIENOL/GEOSM
IN SYNTHASE

(Streptomyces
coelicolor) 		no annotation 4 MET A 183
GLU A 161
GLU A 243
GLU A 237
 None
None
None
MG  A 402 ( 2.7A)
 1.24A 4mj8C-5dz2A:
undetectable		 4mj8C-5dz2A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f6v SUMO-CONJUGATING
ENZYME UBC9

(Homo sapiens) 		PF00179
(UQ_con) 		4 ASN A 140
GLU A 145
TYR A 144
GLU A 143
 None
 1.31A 4mj8C-5f6vA:
undetectable		 4mj8C-5f6vA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7r LMO0178 PROTEIN

(Listeria
monocytogenes) 		no annotation 4 MET E 264
GLU E 263
GLU E 268
GLU E  92
 None
GLC  E 501 (-2.7A)
None
GLC  E 502 (-3.3A)
 1.34A 4mj8C-5f7rE:
undetectable		 4mj8C-5f7rE:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f7s GLYCOSIDE HYDROLASE
FAMILY 31

(Trueperella
pyogenes) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ASN A 305
GLU A 303
GLU A 330
GLU A 335
 None
 1.26A 4mj8C-5f7sA:
undetectable		 4mj8C-5f7sA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihr PROBABLE
BETA-GALACTOSIDASE A

(Aspergillus
niger) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 ASN A 320
GLU A 377
GLU A 381
GLU A 322
 MAN  A1627 (-3.7A)
MAN  A1625 (-2.8A)
None
MAN  A1626 (-3.7A)
 1.26A 4mj8C-5ihrA:
undetectable		 4mj8C-5ihrA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iy7 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB11-A

(Homo sapiens) 		PF13656
(RNA_pol_L_2) 		4 ASN K  36
GLU K  68
GLU K   8
GLU K  16
 None
 1.29A 4mj8C-5iy7K:
undetectable		 4mj8C-5iy7K:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kh0 SMALL GTP-BINDING
PROTEIN

(Thermosipho
melanesiensis) 		PF01926
(MMR_HSR1) 		4 ASN A 131
GLU A 130
GLU A 133
GLU A 135
 None
 1.34A 4mj8C-5kh0A:
undetectable		 4mj8C-5kh0A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzl HEME OXYGENASE

(Leptospira
interrogans) 		PF01126
(Heme_oxygenase) 		4 MET A  51
GLU A  52
GLU A  49
TYR A  46
 None
 1.07A 4mj8C-5kzlA:
undetectable		 4mj8C-5kzlA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ln1 26S PROTEASOME
REGULATORY SUBUNIT
RPN10

(Saccharomyces
cerevisiae) 		PF13519
(VWA_2) 		4 ASN A  12
GLU A  82
GLU A  14
TYR A  15
 None
 1.34A 4mj8C-5ln1A:
undetectable		 4mj8C-5ln1A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nny WIPB

(Legionella
pneumophila) 		no annotation 4 ASN A 165
GLU A 157
GLU A 160
GLU A 164
 None
 1.32A 4mj8C-5nnyA:
undetectable		 4mj8C-5nnyA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE

(Rhizobium sp.
NT-26) 		no annotation 4 ASN A 637
GLU A 629
GLU A 178
TYR A 177
 None
 0.93A 4mj8C-5nqdA:
undetectable		 4mj8C-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nqd ARSENITE OXIDASE
LARGE SUBUNIT AIOA
[3FE-4S] CLUSTER,
MO-MOLYBDOPTERIN
COFACTOR-BINDING
ACTIVE SITE

(Rhizobium sp.
NT-26) 		no annotation 4 MET A 633
GLU A 629
GLU A 178
TYR A 177
 None
 1.22A 4mj8C-5nqdA:
undetectable		 4mj8C-5nqdA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ti8 AMINOTRANSFERASE

(Pseudomonas sp.
M1) 		PF00202
(Aminotran_3) 		4 GLU A 343
GLU A 344
GLU A 336
GLU A  72
 None
 1.30A 4mj8C-5ti8A:
undetectable		 4mj8C-5ti8A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tu9 ACCUMULATION
ASSOCIATED PROTEIN
AAP G58-SPACER-G513
(VARIANT
G5-SPACER-CONSENSUS
G5)

(Staphylococcus
epidermidis) 		PF07501
(G5)
PF17041
(SasG_E) 		4 ASN A  21
GLU A  28
GLU A  29
GLU A  75
 None
 1.08A 4mj8C-5tu9A:
undetectable		 4mj8C-5tu9A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjq GEM-ASSOCIATED
PROTEIN 2

(Homo sapiens) 		no annotation 4 ASN 2 200
GLU 2 204
GLU 2 141
GLU 2 142
 None
 1.36A 4mj8C-5xjq2:
undetectable		 4mj8C-5xjq2:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjs GEM-ASSOCIATED
PROTEIN 2

(Homo sapiens) 		no annotation 4 ASN 2 200
GLU 2 204
GLU 2 141
GLU 2 142
 None
 1.28A 4mj8C-5xjs2:
undetectable		 4mj8C-5xjs2:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c1d UNCONVENTIONAL
MYOSIN-IB

(Rattus
norvegicus) 		no annotation 4 ASN P 397
GLU P 395
GLU P 202
GLU P 392
 None
 1.08A 4mj8C-6c1dP:
undetectable		 4mj8C-6c1dP:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cv9 SHORT TRANSIENT
RECEPTOR POTENTIAL
CHANNEL 6

(Mus musculus) 		no annotation 4 ASN A 904
GLU A 900
GLU A 899
GLU A 906
 None
 1.31A 4mj8C-6cv9A:
undetectable		 4mj8C-6cv9A:
20.11