SIMILAR PATTERNS OF AMINO ACIDS FOR 4M6K_A_FOLA201_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1u70 DIHYDROFOLATE
REDUCTASE

(Mus musculus) 		PF00186
(DHFR_1) 		4 GLU A  30
GLN A  35
ASN A  64
ARG A  70
 MTX  A 187 (-3.0A)
MTX  A 187 (-3.7A)
MTX  A 187 (-3.6A)
MTX  A 187 (-3.1A)
 0.30A 4m6kA-1u70A:
31.4		 4m6kA-1u70A:
89.25