SIMILAR PATTERNS OF AMINO ACIDS FOR 4M51_A_BEZA501_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9a PROTEIN
(PARVALBUMIN)

(Cyprinus carpio) 		PF13499
(EF-hand_7) 		4 ILE A  11
ILE A  49
PHE A  29
LEU A  35
 None
 0.90A 4m51A-1b9aA:
undetectable		 4m51A-1b9aA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ffv CUTM, FLAVOPROTEIN
OF CARBON MONOXIDE
DEHYDROGENASE

(Hydrogenophaga
pseudoflava) 		PF00941
(FAD_binding_5)
PF03450
(CO_deh_flav_C) 		4 ILE C 101
ILE C 116
SER C 129
LEU C  94
 FAD  C1922 (-4.0A)
None
None
None
 0.99A 4m51A-1ffvC:
0.0		 4m51A-1ffvC:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k0r NUSA

(Mycobacterium
tuberculosis) 		PF08529
(NusA_N)
PF13184
(KH_5) 		4 ILE A 207
ILE A 255
SER A 218
LEU A 316
 None
 0.94A 4m51A-1k0rA:
0.0		 4m51A-1k0rA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kpi CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF02353
(CMAS) 		4 ILE A 184
ILE A 210
PHE A 288
LEU A 251
 CO3  A 902 ( 4.5A)
None
10A  A 901 ( 4.9A)
None
 0.99A 4m51A-1kpiA:
0.1		 4m51A-1kpiA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m46 MYOSIN LIGHT CHAIN
IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF13499
(EF-hand_7)
no annotation 		4 ILE B 859
ILE B 866
PHE A  90
LEU A 106
 None
 0.87A 4m51A-1m46B:
undetectable		 4m51A-1m46B:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne7 GLUCOSAMINE-6-PHOSPH
ATE ISOMERASE

(Homo sapiens) 		PF01182
(Glucosamine_iso) 		4 ILE A  99
ILE A  24
PHE A  93
LEU A  39
 None
 0.96A 4m51A-1ne7A:
undetectable		 4m51A-1ne7A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tpy METHOXY MYCOLIC ACID
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF02353
(CMAS) 		4 ILE A 169
ILE A 195
PHE A 273
LEU A 236
 CO3  A 902 ( 4.6A)
16A  A1901 (-4.3A)
None
16A  A1901 (-4.8A)
 0.98A 4m51A-1tpyA:
undetectable		 4m51A-1tpyA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uhw PLECKSTRIN

(Mus musculus) 		PF00610
(DEP) 		4 ILE A  44
ILE A  22
PHE A  91
LEU A  66
 None
 0.89A 4m51A-1uhwA:
undetectable		 4m51A-1uhwA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v3f PLECKSTRIN 2

(Mus musculus) 		PF00610
(DEP) 		4 ILE A  22
ILE A  11
PHE A 102
LEU A  72
 None
 0.92A 4m51A-1v3fA:
undetectable		 4m51A-1v3fA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve0 HYPOTHETICAL PROTEIN
(ST2072)

(Sulfurisphaera
tokodaii) 		PF01894
(UPF0047) 		4 ILE A  93
ILE A 115
SER A  18
PHE A 119
 None
 0.93A 4m51A-1ve0A:
undetectable		 4m51A-1ve0A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		4 ILE C 729
ILE C 755
PHE C 716
LEU C 720
 None
 0.85A 4m51A-1w36C:
undetectable		 4m51A-1w36C:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcg THIOGLUCOSIDASE

(Brevicoryne
brassicae) 		PF00232
(Glyco_hydro_1) 		4 ILE A  68
ILE A  20
SER A  57
LEU A 105
 None
 0.94A 4m51A-1wcgA:
undetectable		 4m51A-1wcgA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z0v PUTATIVE PROTEASE LA
HOMOLOG TYPE

(Archaeoglobus
fulgidus) 		PF05362
(Lon_C) 		4 ILE A 480
ILE A 522
PHE A 613
LEU A 596
 None
 0.65A 4m51A-1z0vA:
undetectable		 4m51A-1z0vA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asb TRANSCRIPTION
ELONGATION PROTEIN
NUSA

(Mycobacterium
tuberculosis) 		PF13184
(KH_5) 		4 ILE A 207
ILE A 255
SER A 218
LEU A 316
 None
 0.98A 4m51A-2asbA:
undetectable		 4m51A-2asbA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN

(Streptococcus
pneumoniae) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 ILE A  36
ILE A   6
PHE A  82
LEU A 106
 None
 0.94A 4m51A-2awaA:
undetectable		 4m51A-2awaA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdw HYPOTHETICAL PROTEIN
K11E8.1D

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		4 ILE A 196
ILE A 119
SER A 122
LEU A 266
 None
 0.97A 4m51A-2bdwA:
undetectable		 4m51A-2bdwA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bii NITRATE REDUCTASE
[NADPH]

(Ogataea angusta) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 ILE A 124
ILE A 109
SER A 108
LEU A 253
 None
 0.96A 4m51A-2biiA:
undetectable		 4m51A-2biiA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggt SCO1 PROTEIN
HOMOLOG,
MITOCHONDRIAL

(Homo sapiens) 		PF02630
(SCO1-SenC) 		4 ILE A 162
ILE A 203
SER A 202
LEU A 142
 None
 0.98A 4m51A-2ggtA:
undetectable		 4m51A-2ggtA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i71 HYPOTHETICAL PROTEIN

(Sulfolobus
solfataricus) 		PF09455
(Cas_DxTHG) 		4 ILE A 216
ILE A 279
SER A 236
PHE A 209
 None
 0.94A 4m51A-2i71A:
undetectable		 4m51A-2i71A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j8m ACETYLTRANSFERASE
PA4866 FROM P.
AERUGINOSA

(Pseudomonas
aeruginosa) 		PF13420
(Acetyltransf_4) 		4 ILE A  19
ILE A  55
SER A  70
LEU A 103
 None
 0.91A 4m51A-2j8mA:
undetectable		 4m51A-2j8mA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jlm PUTATIVE
PHOSPHINOTHRICIN
N-ACETYLTRANSFERASE

(Acinetobacter
baylyi) 		PF13420
(Acetyltransf_4) 		4 ILE A  27
ILE A  63
SER A  78
LEU A 111
 None
 0.87A 4m51A-2jlmA:
undetectable		 4m51A-2jlmA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbx PARVALBUMIN BETA

(Gadus morhua) 		PF13499
(EF-hand_7) 		4 ILE A  12
ILE A  50
PHE A  30
LEU A  36
 None
 0.95A 4m51A-2mbxA:
undetectable		 4m51A-2mbxA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ntb PECTINESTERASE A

(Dickeya
dadantii) 		PF01095
(Pectinesterase) 		4 ILE A 115
ILE A  63
PHE A 122
LEU A  79
 None
 0.87A 4m51A-2ntbA:
undetectable		 4m51A-2ntbA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nv9 A207R PROTEIN,
ARGININE
DECARBOXYLASE

(Paramecium
bursaria
Chlorella virus
1) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ILE A  31
ILE A  26
SER A  23
LEU A  55
 None
 0.99A 4m51A-2nv9A:
3.2		 4m51A-2nv9A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwu UPF0201 PROTEIN
SSO1042

(Sulfolobus
solfataricus) 		PF01877
(RNA_binding) 		4 ILE A  86
ILE A  65
SER A  68
LEU A  73
 None
 0.95A 4m51A-2nwuA:
undetectable		 4m51A-2nwuA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4q 6-PHOSPHOGLUCONATE
DEHYDROGENASE,
DECARBOXYLATING 1

(Saccharomyces
cerevisiae) 		PF00393
(6PGD)
PF03446
(NAD_binding_2) 		4 ILE A 341
ILE A 188
SER A 333
LEU A 388
 None
 0.97A 4m51A-2p4qA:
undetectable		 4m51A-2p4qA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pal PARVALBUMIN

(Esox lucius) 		PF13499
(EF-hand_7) 		4 ILE A  50
ILE A 106
PHE A  70
LEU A   6
 None
None
None
ACE  A   0 ( 3.5A)
 0.92A 4m51A-2palA:
undetectable		 4m51A-2palA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pes URICASE

(Aspergillus
flavus) 		PF01014
(Uricase) 		4 ILE A 142
SER A 199
PHE A 204
LEU A  78
 None
 0.96A 4m51A-2pesA:
undetectable		 4m51A-2pesA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnw MEMBRANE-BOUND LYTIC
MUREIN
TRANSGLYCOSYLASE

(Agrobacterium
fabrum) 		PF03562
(MltA)
PF06725
(3D) 		4 ILE A 215
ILE A 230
SER A 231
PHE A 183
 None
 0.93A 4m51A-2pnwA:
undetectable		 4m51A-2pnwA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qua EXTRACELLULAR LIPASE

(Serratia
marcescens) 		no annotation 4 ILE A 286
ILE A 373
SER A 329
PHE A   4
 None
 0.95A 4m51A-2quaA:
undetectable		 4m51A-2quaA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfb CYTOCHROME P450

(Picrophilus
torridus) 		PF00067
(p450) 		4 ILE A 191
ILE A  70
SER A 175
PHE A 161
 None
 0.94A 4m51A-2rfbA:
undetectable		 4m51A-2rfbA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoa PHOSPHOHYDROLASE

(Klebsiella
aerogenes) 		PF00149
(Metallophos) 		4 ILE A   6
ILE A  66
SER A  69
LEU A  74
 None
 0.94A 4m51A-2zoaA:
2.8		 4m51A-2zoaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiz DNA POLYMERASE
SLIDING CLAMP C

(Sulfurisphaera
tokodaii) 		PF00705
(PCNA_N)
PF02747
(PCNA_C) 		4 ILE C 241
ILE C 143
SER C 206
PHE C  21
 None
 0.97A 4m51A-3aizC:
undetectable		 4m51A-3aizC:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ciy TOLL-LIKE RECEPTOR 3

(Mus musculus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		4 ILE A  45
ILE A  87
PHE A  71
LEU A  80
 NDG  A 724 (-4.3A)
None
None
None
 0.99A 4m51A-3ciyA:
undetectable		 4m51A-3ciyA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dx5 UNCHARACTERIZED
PROTEIN ASBF

(Bacillus
anthracis) 		PF01261
(AP_endonuc_2) 		4 ILE A  32
ILE A  15
SER A  16
LEU A  42
 None
 0.98A 4m51A-3dx5A:
5.6		 4m51A-3dx5A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e13 PUTATIVE IRON-UPTAKE
ABC TRANSPORT
SYSTEM,PERIPLASMIC
IRON-BINDING PROTEIN

(Campylobacter
jejuni) 		PF13343
(SBP_bac_6) 		4 ILE X  58
ILE X 102
SER X 239
LEU X  67
 None
 0.83A 4m51A-3e13X:
undetectable		 4m51A-3e13X:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enq RIBOSE-5-PHOSPHATE
ISOMERASE A

(Vibrio
vulnificus) 		PF06026
(Rib_5-P_isom_A) 		4 ILE A  78
ILE A  46
PHE A  35
LEU A  15
 None
 0.90A 4m51A-3enqA:
undetectable		 4m51A-3enqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbr ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Sulfolobus
solfataricus) 		PF00591
(Glycos_transf_3)
PF02885
(Glycos_trans_3N) 		4 ILE A  28
ILE A   6
PHE A  58
LEU A  45
 None
 0.97A 4m51A-3gbrA:
undetectable		 4m51A-3gbrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi) 		PF01182
(Glucosamine_iso) 		4 ILE A  99
ILE A  24
PHE A  93
LEU A  39
 None
 0.90A 4m51A-3hn6A:
undetectable		 4m51A-3hn6A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcl SPIKE GLYCOPROTEIN

(Murine
coronavirus) 		PF01601
(Corona_S2)
PF09408
(Spike_rec_bind)
PF16451
(Spike_NTD) 		4 ILE A 388
ILE A 375
PHE A 356
LEU A 358
 None
 0.94A 4m51A-3jclA:
undetectable		 4m51A-3jclA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl8 CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE II

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		4 ILE A 195
ILE A 119
SER A 122
LEU A 265
 None
 0.92A 4m51A-3kl8A:
undetectable		 4m51A-3kl8A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obe SUGAR PHOSPHATE
ISOMERASE/EPIMERASE

(Parabacteroides
distasonis) 		PF01261
(AP_endonuc_2) 		4 ILE A 147
ILE A 189
PHE A  90
LEU A 122
 None
 0.94A 4m51A-3obeA:
7.1		 4m51A-3obeA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psf TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		4 ILE A 528
ILE A 519
SER A 520
LEU A 582
 None
 0.97A 4m51A-3psfA:
undetectable		 4m51A-3psfA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q0i METHIONYL-TRNA
FORMYLTRANSFERASE

(Vibrio cholerae) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 ILE A 159
ILE A 114
SER A 113
LEU A 172
 None
 0.92A 4m51A-3q0iA:
undetectable		 4m51A-3q0iA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q5e ATLASTIN-1

(Homo sapiens) 		PF02263
(GBP) 		4 ILE A 125
SER A 171
PHE A 329
LEU A 325
 None
 0.69A 4m51A-3q5eA:
undetectable		 4m51A-3q5eA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkx BIOTIN-[ACETYL-COA-C
ARBOXYLASE] LIGASE

(Staphylococcus
aureus) 		PF03099
(BPL_LplA_LipB)
PF08279
(HTH_11) 		5 ILE A 211
ILE A 183
SER A 169
PHE A 244
LEU A 239
 None
 1.31A 4m51A-3rkxA:
undetectable		 4m51A-3rkxA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 501
ILE A 448
PHE A 489
LEU A 463
 None
 0.85A 4m51A-3szeA:
undetectable		 4m51A-3szeA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tcm ALANINE
AMINOTRANSFERASE 2

(Hordeum vulgare) 		PF00155
(Aminotran_1_2) 		4 ILE A 388
ILE A 466
PHE A 451
LEU A 428
 None
 0.74A 4m51A-3tcmA:
undetectable		 4m51A-3tcmA:
24.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v7p AMIDOHYDROLASE
FAMILY PROTEIN

(Nitratiruptor
sp. SB155-2) 		PF01979
(Amidohydro_1) 		6 ILE A  86
ARG A  89
ILE A 143
SER A 183
PHE A 227
LEU A 232
 None
None
BEZ  A 430 (-4.5A)
BEZ  A 430 (-4.8A)
BEZ  A 430 ( 4.8A)
BEZ  A 430 (-4.5A)
 0.36A 4m51A-3v7pA:
71.1		 4m51A-3v7pA:
99.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zth STU0660

(Streptococcus
thermophilus) 		PF16813
(Cas_St_Csn2) 		4 ILE A 256
ILE A 246
PHE A 325
LEU A 321
 None
 0.89A 4m51A-3zthA:
undetectable		 4m51A-3zthA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8j ELONGATOR COMPLEX
PROTEIN 5

(Saccharomyces
cerevisiae) 		PF10483
(Elong_Iki1) 		4 ILE B  25
ILE B  39
SER B  35
LEU B 204
 None
 0.99A 4m51A-4a8jB:
undetectable		 4m51A-4a8jB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ae0 DIPHTHERIA TOXIN

(Corynebacterium
diphtheriae) 		PF01324
(Diphtheria_R)
PF02763
(Diphtheria_C)
PF02764
(Diphtheria_T) 		4 ILE A 226
ILE A 217
SER A 337
PHE A 250
 None
 0.98A 4m51A-4ae0A:
undetectable		 4m51A-4ae0A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfr PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC S
SUBUNIT BETA ISOFORM

(Mus musculus) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd) 		4 ILE A 911
ARG A 914
ILE A 930
LEU A 811
 None
None
J82  A2000 (-3.6A)
None
 0.99A 4m51A-4bfrA:
undetectable		 4m51A-4bfrA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bpl IMPORTIN SUBUNIT
ALPHA-1A

(Oryza sativa) 		PF00514
(Arm)
PF16186
(Arm_3) 		4 ILE A 251
ILE A 311
SER A 270
LEU A 244
 None
 0.91A 4m51A-4bplA:
undetectable		 4m51A-4bplA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 ILE A 103
ILE A 416
PHE A 408
LEU A 265
 HEM  A1741 ( 3.9A)
None
None
HEM  A1741 (-4.2A)
 0.93A 4m51A-4c51A:
undetectable		 4m51A-4c51A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c6s PROBABLE WRKY
TRANSCRIPTION FACTOR
52

(Arabidopsis
thaliana) 		no annotation 4 ILE A 138
ILE A 133
SER A 130
PHE A  23
 None
 0.96A 4m51A-4c6sA:
undetectable		 4m51A-4c6sA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4db3 N-ACETYL-D-GLUCOSAMI
NE KINASE

(Vibrio
vulnificus) 		PF00480
(ROK) 		4 ILE A 240
ILE A 282
PHE A 134
LEU A 233
 None
 0.95A 4m51A-4db3A:
undetectable		 4m51A-4db3A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dpp DIHYDRODIPICOLINATE
SYNTHASE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00701
(DHDPS) 		4 ILE A 179
ILE A 209
SER A 213
LEU A 186
 None
 0.89A 4m51A-4dppA:
6.7		 4m51A-4dppA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e09 PLASMID PARTITIONING
PROTEIN PARF

(Escherichia
coli) 		PF01656
(CbiA) 		4 ILE A 201
ILE A 194
PHE A   6
LEU A 136
 None
 0.94A 4m51A-4e09A:
2.3		 4m51A-4e09A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8e GLUTATHIONE
S-TRANSFERASE

(Bombyx mori) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 ILE A 171
ILE A 184
PHE A 135
LEU A 109
 None
 0.96A 4m51A-4e8eA:
undetectable		 4m51A-4e8eA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f52 GLOMULIN

(Homo sapiens) 		PF08568
(Kinetochor_Ybp2) 		4 ILE E  57
ILE E  49
PHE E  29
LEU E   6
 None
 0.96A 4m51A-4f52E:
undetectable		 4m51A-4f52E:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fo0 ACTIN-RELATED
PROTEIN 8

(Homo sapiens) 		PF00022
(Actin) 		4 ILE A 236
ILE A 261
PHE A 622
LEU A 616
 None
 0.96A 4m51A-4fo0A:
undetectable		 4m51A-4fo0A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idi ORYZA SATIVA
RURM1-RELATED

(Plasmodium
yoelii) 		PF09138
(Urm1) 		4 ILE A  40
ILE A 110
PHE A 118
LEU A   7
 None
 0.96A 4m51A-4idiA:
undetectable		 4m51A-4idiA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iis BETA-1,3-GLUCANASE
FORM 'RRII GLN 2'

(Hevea
brasiliensis) 		PF00332
(Glyco_hydro_17) 		4 ILE A 162
ILE A 169
SER A 171
LEU A 234
 None
 0.94A 4m51A-4iisA:
6.6		 4m51A-4iisA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iv5 ASPARTATE
CARBAMOYLTRANSFERASE
, PUTATIVE

(Trypanosoma
cruzi) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 ILE A  30
SER A  22
PHE A 187
LEU A 182
 None
 0.84A 4m51A-4iv5A:
undetectable		 4m51A-4iv5A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knh NUP192P

(Chaetomium
thermophilum) 		PF11894
(Nup192) 		4 ILE A 873
ILE A 850
SER A 929
LEU A 934
 None
 0.95A 4m51A-4knhA:
undetectable		 4m51A-4knhA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4koq SINGLE-STRANDED
DNA-BINDING PROTEIN
WHY3, CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF08536
(Whirly) 		4 ILE A 100
ILE A 215
PHE A 227
LEU A 154
 None
 0.96A 4m51A-4koqA:
undetectable		 4m51A-4koqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C

(Butyrivibrio
proteoclasticus) 		PF00150
(Cellulase) 		4 ILE A 228
ILE A 167
SER A 139
LEU A 137
 None
 0.97A 4m51A-4nf7A:
7.0		 4m51A-4nf7A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5v IRON-DEPENDENT
TRANSCRIPTION
REPRESSOR RELATED
PROTEIN

(Thermoplasma
acidophilum) 		PF02742
(Fe_dep_repr_C)
PF04023
(FeoA) 		4 ILE A 203
ILE A 149
PHE A 173
LEU A 174
 None
 0.93A 4m51A-4o5vA:
undetectable		 4m51A-4o5vA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oc9 PUTATIVE
O-ACETYLHOMOSERINE
(THIOL)-LYASE

(Campylobacter
jejuni) 		PF01053
(Cys_Met_Meta_PP) 		4 ILE A 148
ILE A 163
PHE A 129
LEU A 134
 None
 0.85A 4m51A-4oc9A:
undetectable		 4m51A-4oc9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rm4 CYTOCHROME P450

(Bacillus
subtilis) 		PF00067
(p450) 		4 ILE A 248
SER A 136
PHE A 123
LEU A 119
 None
 0.92A 4m51A-4rm4A:
undetectable		 4m51A-4rm4A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA

(Bacillus
subtilis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 ILE A  98
ILE A  59
SER A  15
PHE A  84
 None
 0.90A 4m51A-4tr6A:
undetectable		 4m51A-4tr6A:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wiw GLYCOSIDE HYDROLASE
FAMILY 18

(Desulfitobacterium
hafniense) 		PF00704
(Glyco_hydro_18) 		4 ILE A 419
ILE A 440
PHE A 459
LEU A 429
 None
 0.95A 4m51A-4wiwA:
6.0		 4m51A-4wiwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xfk PUTATIVE BRANCHED
CHAIN AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN

(Brucella ovis) 		PF13458
(Peripla_BP_6) 		4 ILE A 401
ILE A 153
PHE A 206
LEU A 375
 None
 0.92A 4m51A-4xfkA:
undetectable		 4m51A-4xfkA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ymp INTERNALIN

(Bacillus
anthracis) 		PF05031
(NEAT) 		4 ILE A  15
ILE A 118
PHE A  90
LEU A  59
 None
HEM  A 201 (-4.7A)
None
None
 0.95A 4m51A-4ympA:
undetectable		 4m51A-4ympA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0c TOLL-LIKE RECEPTOR
13

(Mus musculus) 		PF00560
(LRR_1)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ILE A 142
ILE A 186
PHE A 170
LEU A 179
 NAG  A 904 (-4.5A)
None
None
None
 0.97A 4m51A-4z0cA:
undetectable		 4m51A-4z0cA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zrx F5/8 TYPE C DOMAIN
PROTEIN

(Bacteroides
ovatus) 		PF00754
(F5_F8_type_C)
PF01120
(Alpha_L_fucos) 		4 ILE A 227
ILE A 185
PHE A 203
LEU A 164
 None
 0.86A 4m51A-4zrxA:
4.8		 4m51A-4zrxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnc HEME BINDING PROTEIN
MSMEG_6519

(Mycolicibacterium
smegmatis) 		PF10615
(DUF2470)
PF13883
(Pyrid_oxidase_2) 		4 ILE A  91
ILE A  37
SER A  40
LEU A  64
 None
 0.70A 4m51A-5bncA:
undetectable		 4m51A-5bncA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cov NAEGLERIA GRUBERI
RNA LIGASE

(Naegleria
gruberi) 		PF09414
(RNA_ligase) 		4 ILE A 228
ILE A 126
SER A 131
LEU A 194
 None
 0.71A 4m51A-5covA:
undetectable		 4m51A-5covA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dte MONOSACCHARIDE-TRANS
PORTING ATPASE

(Actinobacillus
succinogenes) 		PF13407
(Peripla_BP_4) 		4 ILE A 163
ILE A 219
PHE A 184
LEU A 151
 None
 0.98A 4m51A-5dteA:
undetectable		 4m51A-5dteA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fhh ATP-DEPENDENT DNA
HELICASE PIF1

(Homo sapiens) 		PF02689
(Herpes_Helicase)
PF05970
(PIF1) 		4 ILE A 339
ILE A 263
SER A 235
PHE A 226
 None
None
ADP  A 701 ( 2.6A)
None
 0.90A 4m51A-5fhhA:
undetectable		 4m51A-5fhhA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdh TOLL-LIKE RECEPTOR 8

(Homo sapiens) 		PF13855
(LRR_8) 		4 ILE A 399
ILE A 359
PHE A 417
LEU A 413
 None
 0.96A 4m51A-5hdhA:
undetectable		 4m51A-5hdhA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kod INDOLE-3-ACETIC
ACID-AMIDO
SYNTHETASE GH3.5

(Arabidopsis
thaliana) 		PF03321
(GH3) 		4 ILE A 263
SER A 213
PHE A 242
LEU A 250
 None
 0.98A 4m51A-5kodA:
undetectable		 4m51A-5kodA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm7 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA

(Escherichia
coli) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		4 ILE A 273
SER A 263
PHE A 209
LEU A 205
 A  R  12 ( 4.6A)
None
None
None
 0.97A 4m51A-5lm7A:
undetectable		 4m51A-5lm7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm9 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA

(Escherichia
coli) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		4 ILE A 273
SER A 263
PHE A 209
LEU A 205
 None
 0.97A 4m51A-5lm9A:
undetectable		 4m51A-5lm9A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III

(Methanococcoides
burtonii) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 ILE A 266
ILE A 321
SER A 310
PHE A 304
 None
 0.81A 4m51A-5macA:
4.1		 4m51A-5macA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tbk IMPORTIN SUBUNIT
ALPHA-3

(Homo sapiens) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		4 ILE A 462
ILE A 413
PHE A 485
LEU A 439
 None
 0.98A 4m51A-5tbkA:
undetectable		 4m51A-5tbkA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te1 ATP-CITRATE SYNTHASE

(Homo sapiens) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
PF16114
(Citrate_bind) 		4 ILE A 673
ILE A 344
SER A 343
PHE A 790
 None
None
7A2  A 901 (-3.6A)
None
 0.85A 4m51A-5te1A:
undetectable		 4m51A-5te1A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B

(Heterocephalus
glaber) 		no annotation 4 ILE A 269
ILE A 294
SER A 301
LEU A 275
 PG4  A 418 ( 3.8A)
None
None
None
 0.99A 4m51A-5u81A:
undetectable		 4m51A-5u81A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgr ATLASTIN-3

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		4 ILE A 121
SER A 167
PHE A 325
LEU A 321
 None
 0.89A 4m51A-5vgrA:
undetectable		 4m51A-5vgrA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5via PSEUDOPEROXIDASE

(Leishmania
major) 		PF00141
(peroxidase) 		4 ILE A  85
ILE A 325
PHE A 317
LEU A 202
 HEM  A 500 ( 3.9A)
None
None
HEM  A 500 (-4.1A)
 0.95A 4m51A-5viaA:
undetectable		 4m51A-5viaA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vis DIHYDROPTEROATE
SYNTHASE

(soil metagenome) 		PF00809
(Pterin_bind) 		4 ILE A 248
SER A 237
PHE A 217
LEU A 195
 None
 0.98A 4m51A-5visA:
5.9		 4m51A-5visA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7z DNA POLYMERASE III
SUBUNIT BETA

(Rickettsia
conorii) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 ILE A 296
ILE A 330
PHE A 267
LEU A 337
 None
 0.97A 4m51A-5w7zA:
undetectable		 4m51A-5w7zA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wrj PROTEIN-TYROSINE
SULFOTRANSFERASE 1

(Homo sapiens) 		PF13469
(Sulfotransfer_3) 		4 ILE A 146
ILE A 107
PHE A 174
LEU A 170
 None
 0.83A 4m51A-5wrjA:
undetectable		 4m51A-5wrjA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 ILE A1260
ILE A 394
PHE A 785
LEU A 786
 None
 0.98A 4m51A-5xsyA:
undetectable		 4m51A-5xsyA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yz0 SERINE/THREONINE-PRO
TEIN KINASE ATR

(Homo sapiens) 		no annotation 4 ILE A1552
ILE A1532
PHE A1632
LEU A1588
 None
 0.83A 4m51A-5yz0A:
undetectable		 4m51A-5yz0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zh6 -

(-) 		no annotation 4 ILE A  11
ILE A  47
PHE A  27
LEU A  33
 None
 0.91A 4m51A-5zh6A:
undetectable		 4m51A-5zh6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dch SCOE PROTEIN

(Streptomyces
coeruleorubidus) 		no annotation 4 ILE A  58
ILE A 144
PHE A  48
LEU A  86
 None
 0.98A 4m51A-6dchA:
undetectable		 4m51A-6dchA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ekv TOXIN COMPLEX
COMPONENT ORF-X2

(Clostridium
botulinum) 		no annotation 4 ILE A 659
ILE A 666
PHE A 458
LEU A 478
 None
 0.99A 4m51A-6ekvA:
undetectable		 4m51A-6ekvA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1

(Saccharomyces
cerevisiae) 		no annotation 4 ILE A 793
ILE A 558
SER A 561
LEU A 705
 None
 0.96A 4m51A-6f42A:
undetectable		 4m51A-6f42A:
undetectable