SIMILAR PATTERNS OF AMINO ACIDS FOR 4LZR_A_LOCA201_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 13pk | 3-PHOSPHOGLYCERATEKINASE (Trypanosomabrucei) |
PF00162(PGK) | 4 | VAL A 128LEU A 99ASP A 165ILE A 21 | None | 0.82A | 4lzrA-13pkA:undetectable | 4lzrA-13pkA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cg4 | PROTEIN(ADENYLOSUCCINATESYNTHETASE) (Escherichiacoli) |
PF00709(Adenylsucc_synt) | 5 | VAL A 72LEU A 74LEU A 54ASN A 38ILE A 133 | NoneNoneNoneIMO A 440 (-4.0A)IMO A 440 ( 4.4A) | 1.47A | 4lzrA-1cg4A:undetectable | 4lzrA-1cg4A:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 4 | VAL A 160LEU A 148LEU A 157ILE A 97 | None | 0.89A | 4lzrA-1ciyA:0.7 | 4lzrA-1ciyA:10.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddg | SULFITE REDUCTASE(NADPH) FLAVOPROTEINALPHA-COMPONENT (Escherichiacoli) |
PF00175(NAD_binding_1)PF00667(FAD_binding_1) | 4 | VAL A 437LEU A 268LEU A 263ILE A 390 | None | 0.87A | 4lzrA-1ddgA:undetectable | 4lzrA-1ddgA:15.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1e6i | TRANSCRIPTIONALACTIVATOR GCN5 (Saccharomycescerevisiae) |
PF00439(Bromodomain) | 4 | TRP A 350VAL A 356TYR A 406ASN A 407 | None | 0.64A | 4lzrA-1e6iA:15.9 | 4lzrA-1e6iA:34.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f6d | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Escherichiacoli) |
PF02350(Epimerase_2) | 5 | VAL A 255LEU A 259LEU A 267ASP A 289ILE A 225 | None | 1.41A | 4lzrA-1f6dA:undetectable | 4lzrA-1f6dA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f76 | DIHYDROOROTATEDEHYDROGENASE(QUINONE) (Escherichiacoli) |
PF01180(DHO_dh) | 4 | VAL A 230LEU A 222TYR A 186ILE A 173 | None | 0.80A | 4lzrA-1f76A:undetectable | 4lzrA-1f76A:18.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gju | MALTODEXTRINGLYCOSYLTRANSFERASE (Thermotogamaritima) |
PF00128(Alpha-amylase)PF09083(DUF1923) | 4 | VAL A 198LEU A 139LEU A 200ASP A 181 | None | 0.78A | 4lzrA-1gjuA:undetectable | 4lzrA-1gjuA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gkp | HYDANTOINASE (Thermus sp.) |
PF01979(Amidohydro_1) | 4 | LEU A 269LEU A 270ASN A 415ILE A 403 | None | 0.79A | 4lzrA-1gkpA:undetectable | 4lzrA-1gkpA:14.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i1q | ANTHRANILATESYNTHASE COMPONENT IANTHRANILATESYNTHASE COMPONENTII (Salmonellaenterica) |
PF00117(GATase)PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 4 | LEU B 20ASN A 115ASP A 113ILE B 29 | None | 0.85A | 4lzrA-1i1qB:undetectable | 4lzrA-1i1qB:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i9z | PHOSPHATIDYLINOSITOLPHOSPHATEPHOSPHATASE (Schizosaccharomycespombe) |
PF03372(Exo_endo_phos) | 4 | VAL A 736LEU A 824ASP A 589ILE A 590 | None | 0.79A | 4lzrA-1i9zA:undetectable | 4lzrA-1i9zA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ikp | EXOTOXIN A (Pseudomonasaeruginosa) |
PF09009(Exotox-A_cataly)PF09101(Exotox-A_bind)PF09102(Exotox-A_target) | 4 | TRP A 190LEU A 199LEU A 202ILE A 132 | None | 0.89A | 4lzrA-1ikpA:undetectable | 4lzrA-1ikpA:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jf5 | ALPHA AMYLASE II (Thermoactinomycesvulgaris) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16657(Malt_amylase_C) | 5 | VAL A 175LEU A 182LEU A 179ASP A 320ILE A 236 | None | 1.45A | 4lzrA-1jf5A:undetectable | 4lzrA-1jf5A:12.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl5 | OUTER PROTEIN YOPM (Yersinia pestis) |
PF12468(TTSSLRR) | 4 | VAL A1138LEU A1123LEU A1143ASP A1128 | None | 0.76A | 4lzrA-1jl5A:undetectable | 4lzrA-1jl5A:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jl5 | OUTER PROTEIN YOPM (Yersinia pestis) |
PF12468(TTSSLRR) | 4 | VAL A1264LEU A1249LEU A1269ASP A1254 | None | 0.85A | 4lzrA-1jl5A:undetectable | 4lzrA-1jl5A:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqo | PHOSPHOENOLPYRUVATECARBOXYLASE (Zea mays) |
PF00311(PEPcase) | 4 | VAL A 263LEU A 165LEU A 276ILE A 283 | None | 0.89A | 4lzrA-1jqoA:2.1 | 4lzrA-1jqoA:8.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcz | BETA-METHYLASPARTASE (Clostridiumtetanomorphum) |
PF05034(MAAL_N)PF07476(MAAL_C) | 4 | VAL A 239LEU A 211LEU A 204ILE A 258 | None | 0.81A | 4lzrA-1kczA:undetectable | 4lzrA-1kczA:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kkr | 3-METHYLASPARTATEAMMONIA-LYASE (Citrobacteramalonaticus) |
PF05034(MAAL_N)PF07476(MAAL_C) | 4 | VAL A 239LEU A 211LEU A 204ILE A 258 | None | 0.89A | 4lzrA-1kkrA:undetectable | 4lzrA-1kkrA:16.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ks8 | ENDO-B-1,4-GLUCANASE (Nasutitermestakasagoensis) |
PF00759(Glyco_hydro_9) | 5 | TRP A 74LEU A 320LEU A 322TYR A 327ILE A 313 | None | 1.50A | 4lzrA-1ks8A:undetectable | 4lzrA-1ks8A:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mbm | CHYMOTRYPSIN-LIKESERINE PROTEASE (Equinearteritis virus) |
PF05579(Peptidase_S32) | 4 | VAL A 189LEU A 193ASP A 177ILE A 178 | None | 0.88A | 4lzrA-1mbmA:undetectable | 4lzrA-1mbmA:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mr2 | ADPR PYROPHOSPHATASE (Mycobacteriumtuberculosis) |
PF00293(NUDIX) | 4 | VAL A 98LEU A 100LEU A 94ILE A 57 | None | 0.85A | 4lzrA-1mr2A:undetectable | 4lzrA-1mr2A:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1no5 | HYPOTHETICAL PROTEINHI0073 (Haemophilusinfluenzae) |
PF01909(NTP_transf_2) | 4 | VAL A 78LEU A 49LEU A 80ILE A 20 | None | 0.92A | 4lzrA-1no5A:undetectable | 4lzrA-1no5A:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ohe | CDC14B2 PHOSPHATASE (Homo sapiens) |
PF00782(DSPc)PF14671(DSPn) | 5 | VAL A 312LEU A 263LEU A 324ASP A 301ILE A 302 | None | 1.19A | 4lzrA-1oheA:undetectable | 4lzrA-1oheA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ose | PORCINEALPHA-AMYLASE (Sus scrofa) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C) | 4 | VAL A 210LEU A 170ASP A 197ILE A 196 | NoneNoneAC1 A 992 ( 3.3A)None | 0.84A | 4lzrA-1oseA:undetectable | 4lzrA-1oseA:12.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ouu | HEMOGLOBIN I (Oncorhynchusmykiss) |
PF00042(Globin) | 4 | VAL A 126LEU A 107LEU A 110ILE A 67 | None | 0.91A | 4lzrA-1ouuA:undetectable | 4lzrA-1ouuA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q1q | SULFOTRANSFERASEFAMILY, CYTOSOLIC,2B, MEMBER 1 ISOFORMA (Homo sapiens) |
PF00685(Sulfotransfer_1) | 4 | VAL A 225LEU A 222LEU A 217ILE A 209 | None | 0.87A | 4lzrA-1q1qA:undetectable | 4lzrA-1q1qA:15.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5m | PROSTAGLANDIN-E29-REDUCTASE (Oryctolaguscuniculus) |
PF00248(Aldo_ket_red) | 4 | LEU A 108LEU A 106ASP A 50ILE A 49 | NoneNoneNDP A1003 (-3.7A)None | 0.89A | 4lzrA-1q5mA:undetectable | 4lzrA-1q5mA:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgj | PEROXIDASE N (Arabidopsisthaliana) |
PF00141(peroxidase) | 4 | VAL A 22LEU A 36ASP A 96ILE A 97 | None | 0.86A | 4lzrA-1qgjA:undetectable | 4lzrA-1qgjA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgj | PEROXIDASE N (Arabidopsisthaliana) |
PF00141(peroxidase) | 5 | VAL A 259LEU A 233LEU A 232TYR A 228ASP A 225 | NoneNoneNoneNone CA A2002 (-2.9A) | 1.47A | 4lzrA-1qgjA:undetectable | 4lzrA-1qgjA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qho | ALPHA-AMYLASE (Geobacillusstearothermophilus) |
PF00128(Alpha-amylase)PF00686(CBM_20)PF01833(TIG)PF02806(Alpha-amylase_C) | 4 | VAL A 54LEU A 61LEU A 58ASP A 223 | None | 0.92A | 4lzrA-1qhoA:undetectable | 4lzrA-1qhoA:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwk | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C1 (Caenorhabditiselegans) |
PF00248(Aldo_ket_red) | 4 | LEU A 65LEU A 66ASP A 109ILE A 78 | None | 0.90A | 4lzrA-1qwkA:undetectable | 4lzrA-1qwkA:17.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r3f | TRNA PSEUDOURIDINESYNTHASE B (Escherichiacoli) |
PF01509(TruB_N)PF09157(TruB-C_2)PF16198(TruB_C_2) | 4 | LEU A 216LEU A 219TYR A 36ILE A 57 | None | 0.82A | 4lzrA-1r3fA:undetectable | 4lzrA-1r3fA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r47 | ALPHA-GALACTOSIDASEA (Homo sapiens) |
PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 4 | VAL A 351LEU A 415LEU A 417ILE A 367 | None | 0.91A | 4lzrA-1r47A:undetectable | 4lzrA-1r47A:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s9u | PUTATIVE COMPONENTOF ANAEROBICDEHYDROGENASES (Salmonellaenterica) |
PF02613(Nitrate_red_del) | 5 | VAL A 56LEU A 181LEU A 184ASP A 164ILE A 167 | None | 1.39A | 4lzrA-1s9uA:2.4 | 4lzrA-1s9uA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sbp | SULFATE-BINDINGPROTEIN (Salmonellaenterica) |
PF13531(SBP_bac_11) | 5 | LEU A 243LEU A 246TYR A 20ASN A 21ILE A 38 | None | 1.44A | 4lzrA-1sbpA:undetectable | 4lzrA-1sbpA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sch | PEANUT PEROXIDASE,MAJOR CATIONICISOZYME (Arachishypogaea) |
PF00141(peroxidase) | 4 | VAL A 22LEU A 36ASP A 99ILE A 100 | None | 0.89A | 4lzrA-1schA:undetectable | 4lzrA-1schA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1slj | RIBONUCLEASE E (Escherichiacoli) |
PF00575(S1) | 5 | VAL A 58LEU A 116LEU A 68TYR A 77ILE A 101 | None | 1.20A | 4lzrA-1sljA:undetectable | 4lzrA-1sljA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1snn | 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATESYNTHASE (Methanocaldococcusjannaschii) |
PF00926(DHBP_synthase) | 4 | VAL A 4LEU A 171LEU A 174ILE A 217 | None | 0.81A | 4lzrA-1snnA:undetectable | 4lzrA-1snnA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uiy | ENOYL-COA HYDRATASE (Thermusthermophilus) |
PF00378(ECH_1) | 4 | VAL A 164LEU A 172LEU A 174TYR A 129 | None | 0.91A | 4lzrA-1uiyA:undetectable | 4lzrA-1uiyA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v4n | 271AA LONGHYPOTHETICAL5'-METHYLTHIOADENOSINE PHOSPHORYLASE (Sulfurisphaeratokodaii) |
PF01048(PNP_UDP_1) | 4 | LEU A 49LEU A 25TYR A 20ILE A 13 | None | 0.90A | 4lzrA-1v4nA:undetectable | 4lzrA-1v4nA:18.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w8g | HYPOTHETICAL UPF0001PROTEIN YGGS (Escherichiacoli) |
PF01168(Ala_racemase_N) | 4 | VAL A 152LEU A 155LEU A 158ILE A 108 | NoneNoneNoneICT A1230 ( 4.2A) | 0.81A | 4lzrA-1w8gA:undetectable | 4lzrA-1w8gA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x3l | HYPOTHETICAL PROTEINPH0495 (Pyrococcushorikoshii) |
PF05161(MOFRL)PF13660(DUF4147) | 4 | LEU A 192LEU A 128ASP A 69ILE A 70 | None | 0.78A | 4lzrA-1x3lA:undetectable | 4lzrA-1x3lA:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr4 | PUTATIVE CITRATELYASE ALPHACHAIN/CITRATE-ACPTRANSFERASE (Salmonellaenterica) |
PF04223(CitF) | 4 | VAL A 433LEU A 449LEU A 453ILE A 258 | None | 0.82A | 4lzrA-1xr4A:undetectable | 4lzrA-1xr4A:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yfy | 3-HYDROXYANTHRANILATE-3,4-DIOXYGENASE (Cupriavidusmetallidurans) |
PF06052(3-HAO) | 4 | TRP A 31VAL A 40LEU A 107LEU A 62 | None | 0.85A | 4lzrA-1yfyA:undetectable | 4lzrA-1yfyA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytm | PHOSPHOENOLPYRUVATECARBOXYKINASE [ATP] (Anaerobiospirillumsucciniciproducens) |
PF01293(PEPCK_ATP) | 4 | VAL A 170LEU A 176LEU A 178ILE A 194 | None | 0.86A | 4lzrA-1ytmA:undetectable | 4lzrA-1ytmA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a6q | ANTITOXIN YEFM (Escherichiacoli) |
PF02604(PhdYeFM_antitox) | 4 | LEU A 63LEU A 64ASP A 78ILE A 77 | None | 0.78A | 4lzrA-2a6qA:undetectable | 4lzrA-2a6qA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b7h | HEMOGLOBIN ALPHACHAIN (Cerdocyon thous) |
PF00042(Globin) | 4 | LEU A 109LEU A 106ASP A 6ILE A 10 | None | 0.79A | 4lzrA-2b7hA:undetectable | 4lzrA-2b7hA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmb | FOLIC ACID SYNTHESISPROTEIN FOL1 (Saccharomycescerevisiae) |
PF00809(Pterin_bind)PF01288(HPPK) | 5 | TRP A 750VAL A 395LEU A 370LEU A 362ILE A 355 | None | 1.47A | 4lzrA-2bmbA:undetectable | 4lzrA-2bmbA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bqx | INORGANICPYROPHOSPHATASE (Helicobacterpylori) |
PF00719(Pyrophosphatase) | 4 | LEU A 73LEU A 107ASP A 123ILE A 122 | None | 0.86A | 4lzrA-2bqxA:undetectable | 4lzrA-2bqxA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c2y | METHYLENETETRAHYDROFOLATEDEHYDROGENASE-METHENYLTETRAHYDROFOLATECYCLOHYDROLASE (Mycobacteriumtuberculosis) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | LEU A 100LEU A 104ASN A 79ILE A 82 | None | 0.92A | 4lzrA-2c2yA:undetectable | 4lzrA-2c2yA:15.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb1 | O-ACETYL HOMOSERINESULFHYDRYLASE (Thermusthermophilus) |
PF01053(Cys_Met_Meta_PP) | 4 | VAL A 389LEU A 333LEU A 335ILE A 348 | None | 0.82A | 4lzrA-2cb1A:undetectable | 4lzrA-2cb1A:14.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cg9 | ATP-DEPENDENTMOLECULAR CHAPERONEHSP82 (Saccharomycescerevisiae) |
PF00183(HSP90)PF02518(HATPase_c) | 4 | VAL A 136LEU A 89LEU A 93ASP A 40 | NoneNoneNoneATP A1678 ( 4.9A) | 0.84A | 4lzrA-2cg9A:undetectable | 4lzrA-2cg9A:11.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dcq | PUTATIVE PROTEINAT4G01050 (Arabidopsisthaliana) |
no annotation | 5 | VAL A 94LEU A 62LEU A 65ASP A 26ILE A 27 | None | 1.35A | 4lzrA-2dcqA:undetectable | 4lzrA-2dcqA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dld | D-LACTATEDEHYDROGENASE (Lactobacillushelveticus) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | VAL A 52LEU A 36ASN A 83ILE A 84 | None | 0.90A | 4lzrA-2dldA:undetectable | 4lzrA-2dldA:16.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2dvr | BROMODOMAIN-CONTAINING PROTEIN 2 (Homo sapiens) |
PF00439(Bromodomain) | 7 | TRP A 31VAL A 37LEU A 42LEU A 44TYR A 89ASN A 90ILE A 96 | None | 0.63A | 4lzrA-2dvrA:20.2 | 4lzrA-2dvrA:67.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2dvr | BROMODOMAIN-CONTAINING PROTEIN 2 (Homo sapiens) |
PF00439(Bromodomain) | 6 | TRP A 31VAL A 37TYR A 89ASN A 90ASP A 94ILE A 96 | None | 0.64A | 4lzrA-2dvrA:20.2 | 4lzrA-2dvrA:67.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2dvr | BROMODOMAIN-CONTAINING PROTEIN 2 (Homo sapiens) |
PF00439(Bromodomain) | 5 | VAL A 37LEU A 42ASN A 90ASP A 94ILE A 96 | None | 1.26A | 4lzrA-2dvrA:20.2 | 4lzrA-2dvrA:67.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fvl | ALDO-KETO REDUCTASEFAMILY 1, MEMBER C4 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | LEU A 108LEU A 106ASP A 50ILE A 49 | NoneNoneNAP A1001 (-3.7A)None | 0.88A | 4lzrA-2fvlA:undetectable | 4lzrA-2fvlA:17.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g37 | PROLINEDEHYDROGENASE/DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE (Thermusthermophilus) |
PF01619(Pro_dh) | 4 | VAL A 119LEU A 116LEU A 103ASP A 61 | None | 0.90A | 4lzrA-2g37A:undetectable | 4lzrA-2g37A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gep | SULFITE REDUCTASEHEMOPROTEIN (Escherichiacoli) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | VAL A 491LEU A 505LEU A 503ASP A 532ILE A 535 | None | 1.34A | 4lzrA-2gepA:undetectable | 4lzrA-2gepA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gnp | TRANSCRIPTIONALREGULATOR (Streptococcuspneumoniae) |
PF04198(Sugar-bind) | 4 | VAL A 208LEU A 141ASP A 204ILE A 205 | None | 0.86A | 4lzrA-2gnpA:undetectable | 4lzrA-2gnpA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gs9 | HYPOTHETICAL PROTEINTT1324 (Thermusthermophilus) |
PF08241(Methyltransf_11) | 4 | VAL A 131LEU A 166LEU A 170ASP A 111 | None | 0.87A | 4lzrA-2gs9A:undetectable | 4lzrA-2gs9A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hh9 | THIAMINPYROPHOSPHOKINASE (Candidaalbicans) |
PF04263(TPK_catalytic)PF04265(TPK_B1_binding) | 4 | VAL A 319LEU A 268LEU A 270ILE A 200 | None | 0.85A | 4lzrA-2hh9A:undetectable | 4lzrA-2hh9A:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnz | REVERSETRANSCRIPTASE/RIBONUCLEASE H (Humanimmunodeficiencyvirus 1) |
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 5 | VAL A 531LEU A 533LEU A 429TYR A 427ILE A 521 | None | 1.21A | 4lzrA-2hnzA:1.4 | 4lzrA-2hnzA:13.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ho9 | CHEMOTAXIS PROTEINCHEW (Escherichiacoli) |
PF01584(CheW) | 4 | VAL A 102LEU A 71TYR A 29ILE A 31 | None | 0.88A | 4lzrA-2ho9A:undetectable | 4lzrA-2ho9A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipj | ALDO-KETO REDUCTASEFAMILY 1 MEMBER C2 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | LEU A 108LEU A 106ASP A 50ILE A 49 | NoneNoneNAP A 1 (-3.7A)None | 0.91A | 4lzrA-2ipjA:undetectable | 4lzrA-2ipjA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2it1 | 362AA LONGHYPOTHETICALMALTOSE/MALTODEXTRINTRANSPORTATP-BINDING PROTEIN (Pyrococcushorikoshii) |
PF00005(ABC_tran) | 4 | VAL A 172LEU A 161LEU A 164ILE A 144 | None | 0.80A | 4lzrA-2it1A:undetectable | 4lzrA-2it1A:16.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2l5e | BROMODOMAIN-CONTAINING PROTEIN 3 (Mus musculus) |
PF00439(Bromodomain) | 6 | LEU A 68LEU A 70TYR A 115ASN A 116ASP A 120ILE A 122 | None | 0.84A | 4lzrA-2l5eA:17.5 | 4lzrA-2l5eA:74.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2l5e | BROMODOMAIN-CONTAINING PROTEIN 3 (Mus musculus) |
PF00439(Bromodomain) | 6 | TRP A 57LEU A 68LEU A 70TYR A 115ASN A 116ILE A 122 | None | 0.99A | 4lzrA-2l5eA:17.5 | 4lzrA-2l5eA:74.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2l5e | BROMODOMAIN-CONTAINING PROTEIN 3 (Mus musculus) |
PF00439(Bromodomain) | 6 | VAL A 63LEU A 68LEU A 70TYR A 115ASN A 116ASP A 120 | None | 1.10A | 4lzrA-2l5eA:17.5 | 4lzrA-2l5eA:74.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mbg | RALA-BINDING PROTEIN1 (Homo sapiens) |
PF00620(RhoGAP) | 4 | VAL A 350LEU A 278LEU A 279ILE A 322 | None | 0.78A | 4lzrA-2mbgA:undetectable | 4lzrA-2mbgA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nxp | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 5 (Homo sapiens) |
PF04494(TFIID_NTD2) | 4 | LEU A 236LEU A 239ASP A 340ILE A 341 | None | 0.86A | 4lzrA-2nxpA:undetectable | 4lzrA-2nxpA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 4 | LEU A 507LEU A 508ASP A 484ILE A 487 | None | 0.85A | 4lzrA-2ocfA:undetectable | 4lzrA-2ocfA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2omv | INTERNALIN-A (Listeriamonocytogenes) |
PF08191(LRR_adjacent)PF12354(Internalin_N)PF12799(LRR_4) | 4 | VAL A 357LEU A 344LEU A 366ILE A 351 | None | 0.87A | 4lzrA-2omvA:undetectable | 4lzrA-2omvA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2owo | DNA LIGASE (Escherichiacoli) |
PF01653(DNA_ligase_aden)PF03119(DNA_ligase_ZBD)PF03120(DNA_ligase_OB)PF12826(HHH_2)PF14520(HHH_5) | 4 | VAL A 444LEU A 474LEU A 500ILE A 458 | None | 0.91A | 4lzrA-2owoA:undetectable | 4lzrA-2owoA:12.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p2m | ACETYL-COENZYME ASYNTHETASE (Salmonellaenterica) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 4 | LEU A 317LEU A 321TYR A 110ILE A 108 | None | 0.88A | 4lzrA-2p2mA:undetectable | 4lzrA-2p2mA:11.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5z | TYPE VI SECRETIONSYSTEM COMPONENT (Escherichiacoli) |
PF05954(Phage_GPD) | 5 | VAL X 173LEU X 170LEU X 115ASP X 147ILE X 197 | None | 1.23A | 4lzrA-2p5zX:undetectable | 4lzrA-2p5zX:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p8u | HYDROXYMETHYLGLUTARYL-COA SYNTHASE,CYTOPLASMIC (Homo sapiens) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | VAL A 156LEU A 108ASP A 64ILE A 65 | None | 0.86A | 4lzrA-2p8uA:undetectable | 4lzrA-2p8uA:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfi | CHLORIDE CHANNELPROTEIN CLC-KA (Homo sapiens) |
PF00571(CBS) | 4 | VAL A 594LEU A 558ASP A 620ILE A 621 | None | 0.89A | 4lzrA-2pfiA:undetectable | 4lzrA-2pfiA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pp3 | L-TALARATE/GALACTARATE DEHYDRATASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 154LEU A 155ASP A 109ILE A 108 | None | 0.91A | 4lzrA-2pp3A:undetectable | 4lzrA-2pp3A:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3g | PDZ AND LIM DOMAINPROTEIN 7 (Homo sapiens) |
PF00595(PDZ) | 4 | LEU A 77LEU A 8ASP A 48ILE A 30 | None | 0.85A | 4lzrA-2q3gA:undetectable | 4lzrA-2q3gA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r0v | CHROMATINSTRUCTURE-REMODELINGCOMPLEX PROTEIN RSC4 (Saccharomycescerevisiae) |
PF00439(Bromodomain) | 4 | VAL A 217LEU A 222ASN A 268ILE A 274 | None | 0.88A | 4lzrA-2r0vA:12.9 | 4lzrA-2r0vA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rir | DIPICOLINATESYNTHASE, A CHAIN (Bacillussubtilis) |
PF01262(AlaDh_PNT_C)PF16924(DpaA_N) | 4 | VAL A 210LEU A 206ASP A 241ILE A 239 | None | 0.85A | 4lzrA-2rirA:undetectable | 4lzrA-2rirA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ux7 | PSEUDOAZURIN (Achromobactercycloclastes) |
PF00127(Copper-bind) | 4 | VAL A 87LEU A 120LEU A 117ASN A 96 | None | 0.91A | 4lzrA-2ux7A:undetectable | 4lzrA-2ux7A:23.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzc | PDZ AND LIM DOMAIN 5 (Homo sapiens) |
PF00595(PDZ) | 4 | LEU A 77LEU A 8ASP A 48ILE A 30 | None | 0.91A | 4lzrA-2uzcA:undetectable | 4lzrA-2uzcA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vgq | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN,MITOCHONDRIALANTIVIRAL-SIGNALINGPROTEIN (Escherichiacoli;Homo sapiens) |
PF13416(SBP_bac_8)PF16739(CARD_2) | 4 | VAL A 391LEU A 453LEU A 445ILE A 381 | None | 0.83A | 4lzrA-2vgqA:undetectable | 4lzrA-2vgqA:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vpq | ACETYL-COACARBOXYLASE (Staphylococcusaureus) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | VAL A 213LEU A 308LEU A 311ASP A 327ILE A 328 | None | 1.39A | 4lzrA-2vpqA:undetectable | 4lzrA-2vpqA:13.13 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2wp1 | BROMODOMAINTESTIS-SPECIFICPROTEIN (Mus musculus) |
PF00439(Bromodomain) | 6 | TRP A 292VAL A 298LEU A 303LEU A 305TYR A 350ASN A 351 | None | 0.78A | 4lzrA-2wp1A:16.6 | 4lzrA-2wp1A:38.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wu5 | SUCCINATEDEHYDROGENASEFLAVOPROTEIN SUBUNIT (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | VAL A 190LEU A 183LEU A 167ASN A 445 | None | 0.86A | 4lzrA-2wu5A:undetectable | 4lzrA-2wu5A:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wya | HYDROXYMETHYLGLUTARYL-COA SYNTHASE,MITOCHONDRIAL (Homo sapiens) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | VAL A 193LEU A 145ASP A 101ILE A 102 | None | 0.82A | 4lzrA-2wyaA:undetectable | 4lzrA-2wyaA:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x40 | BETA-GLUCOSIDASE (Thermotoganeapolitana) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | LEU A 11LEU A 8ASP A 258ILE A 300 | None | 0.88A | 4lzrA-2x40A:undetectable | 4lzrA-2x40A:12.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y3w | SPINDLE ASSEMBLYABNORMAL PROTEIN 6HOMOLOG (Danio rerio) |
PF16531(SAS-6_N) | 4 | VAL A 28LEU A 10ASP A 89ILE A 88 | None | 0.91A | 4lzrA-2y3wA:undetectable | 4lzrA-2y3wA:22.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2yek | BROMODOMAIN-CONTAINING PROTEIN 2 (Homo sapiens) |
PF00439(Bromodomain) | 6 | TRP A 97VAL A 103LEU A 108LEU A 110TYR A 155ILE A 162 | NoneEAM A1188 (-4.4A)EAM A1188 ( 3.8A)EAM A1188 (-4.5A)NoneEAM A1188 (-3.8A) | 0.56A | 4lzrA-2yekA:20.2 | 4lzrA-2yekA:66.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2yek | BROMODOMAIN-CONTAINING PROTEIN 2 (Homo sapiens) |
PF00439(Bromodomain) | 7 | TRP A 97VAL A 103LEU A 110TYR A 155ASN A 156ASP A 160ILE A 162 | NoneEAM A1188 (-4.4A)EAM A1188 (-4.5A)NoneEAM A1188 (-3.2A)NoneEAM A1188 (-3.8A) | 0.61A | 4lzrA-2yekA:20.2 | 4lzrA-2yekA:66.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2yek | BROMODOMAIN-CONTAINING PROTEIN 2 (Homo sapiens) |
PF00439(Bromodomain) | 5 | VAL A 103LEU A 108ASN A 156ASP A 160ILE A 162 | EAM A1188 (-4.4A)EAM A1188 ( 3.8A)EAM A1188 (-3.2A)NoneEAM A1188 (-3.8A) | 1.11A | 4lzrA-2yekA:20.2 | 4lzrA-2yekA:66.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvx | MG2+ TRANSPORTERMGTE (Thermusthermophilus) |
PF00571(CBS)PF01769(MgtE)PF03448(MgtE_N) | 5 | VAL A 174LEU A 180LEU A 239TYR A 142ILE A 171 | None | 1.39A | 4lzrA-2yvxA:undetectable | 4lzrA-2yvxA:11.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywa | HYPOTHETICAL PROTEINTTHA0048 (Thermusthermophilus) |
PF08780(NTase_sub_bind) | 5 | LEU A 11LEU A 15TYR A 98ASP A 25ILE A 28 | None | 1.24A | 4lzrA-2ywaA:undetectable | 4lzrA-2ywaA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z51 | NIFU-LIKE PROTEIN 2,CHLOROPLAST (Arabidopsisthaliana) |
PF01106(NifU) | 4 | VAL A 39LEU A 29LEU A 13ILE A 70 | None | 0.89A | 4lzrA-2z51A:undetectable | 4lzrA-2z51A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5x | AMINE OXIDASE[FLAVIN-CONTAINING]A (Homo sapiens) |
PF01593(Amino_oxidase) | 5 | VAL A 37LEU A 460LEU A 463TYR A 268ILE A 270 | None | 1.40A | 4lzrA-2z5xA:undetectable | 4lzrA-2z5xA:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z8u | TATA-BOX-BINDINGPROTEIN (Methanocaldococcusjannaschii) |
PF00352(TBP) | 4 | VAL A 25LEU A 42LEU A 22ILE A 16 | None | 0.88A | 4lzrA-2z8uA:undetectable | 4lzrA-2z8uA:19.90 |