SIMILAR PATTERNS OF AMINO ACIDS FOR 4LZR_A_LOCA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13pk 3-PHOSPHOGLYCERATE
KINASE


(Trypanosoma
brucei)
PF00162
(PGK)
4 VAL A 128
LEU A  99
ASP A 165
ILE A  21
None
0.82A 4lzrA-13pkA:
undetectable
4lzrA-13pkA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cg4 PROTEIN
(ADENYLOSUCCINATE
SYNTHETASE)


(Escherichia
coli)
PF00709
(Adenylsucc_synt)
5 VAL A  72
LEU A  74
LEU A  54
ASN A  38
ILE A 133
None
None
None
IMO  A 440 (-4.0A)
IMO  A 440 ( 4.4A)
1.47A 4lzrA-1cg4A:
undetectable
4lzrA-1cg4A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ciy CRYIA(A)

(Bacillus
thuringiensis)
PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N)
4 VAL A 160
LEU A 148
LEU A 157
ILE A  97
None
0.89A 4lzrA-1ciyA:
0.7
4lzrA-1ciyA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ddg SULFITE REDUCTASE
(NADPH) FLAVOPROTEIN
ALPHA-COMPONENT


(Escherichia
coli)
PF00175
(NAD_binding_1)
PF00667
(FAD_binding_1)
4 VAL A 437
LEU A 268
LEU A 263
ILE A 390
None
0.87A 4lzrA-1ddgA:
undetectable
4lzrA-1ddgA:
15.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1e6i TRANSCRIPTIONAL
ACTIVATOR GCN5


(Saccharomyces
cerevisiae)
PF00439
(Bromodomain)
4 TRP A 350
VAL A 356
TYR A 406
ASN A 407
None
0.64A 4lzrA-1e6iA:
15.9
4lzrA-1e6iA:
34.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6d UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE


(Escherichia
coli)
PF02350
(Epimerase_2)
5 VAL A 255
LEU A 259
LEU A 267
ASP A 289
ILE A 225
None
1.41A 4lzrA-1f6dA:
undetectable
4lzrA-1f6dA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f76 DIHYDROOROTATE
DEHYDROGENASE
(QUINONE)


(Escherichia
coli)
PF01180
(DHO_dh)
4 VAL A 230
LEU A 222
TYR A 186
ILE A 173
None
0.80A 4lzrA-1f76A:
undetectable
4lzrA-1f76A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gju MALTODEXTRIN
GLYCOSYLTRANSFERASE


(Thermotoga
maritima)
PF00128
(Alpha-amylase)
PF09083
(DUF1923)
4 VAL A 198
LEU A 139
LEU A 200
ASP A 181
None
0.78A 4lzrA-1gjuA:
undetectable
4lzrA-1gjuA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gkp HYDANTOINASE

(Thermus sp.)
PF01979
(Amidohydro_1)
4 LEU A 269
LEU A 270
ASN A 415
ILE A 403
None
0.79A 4lzrA-1gkpA:
undetectable
4lzrA-1gkpA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i1q ANTHRANILATE
SYNTHASE COMPONENT I
ANTHRANILATE
SYNTHASE COMPONENT
II


(Salmonella
enterica)
PF00117
(GATase)
PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N)
4 LEU B  20
ASN A 115
ASP A 113
ILE B  29
None
0.85A 4lzrA-1i1qB:
undetectable
4lzrA-1i1qB:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i9z PHOSPHATIDYLINOSITOL
PHOSPHATE
PHOSPHATASE


(Schizosaccharomyces
pombe)
PF03372
(Exo_endo_phos)
4 VAL A 736
LEU A 824
ASP A 589
ILE A 590
None
0.79A 4lzrA-1i9zA:
undetectable
4lzrA-1i9zA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ikp EXOTOXIN A

(Pseudomonas
aeruginosa)
PF09009
(Exotox-A_cataly)
PF09101
(Exotox-A_bind)
PF09102
(Exotox-A_target)
4 TRP A 190
LEU A 199
LEU A 202
ILE A 132
None
0.89A 4lzrA-1ikpA:
undetectable
4lzrA-1ikpA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jf5 ALPHA AMYLASE II

(Thermoactinomyces
vulgaris)
PF00128
(Alpha-amylase)
PF02903
(Alpha-amylase_N)
PF16657
(Malt_amylase_C)
5 VAL A 175
LEU A 182
LEU A 179
ASP A 320
ILE A 236
None
1.45A 4lzrA-1jf5A:
undetectable
4lzrA-1jf5A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis)
PF12468
(TTSSLRR)
4 VAL A1138
LEU A1123
LEU A1143
ASP A1128
None
0.76A 4lzrA-1jl5A:
undetectable
4lzrA-1jl5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl5 OUTER PROTEIN YOPM

(Yersinia pestis)
PF12468
(TTSSLRR)
4 VAL A1264
LEU A1249
LEU A1269
ASP A1254
None
0.85A 4lzrA-1jl5A:
undetectable
4lzrA-1jl5A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqo PHOSPHOENOLPYRUVATE
CARBOXYLASE


(Zea mays)
PF00311
(PEPcase)
4 VAL A 263
LEU A 165
LEU A 276
ILE A 283
None
0.89A 4lzrA-1jqoA:
2.1
4lzrA-1jqoA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcz BETA-METHYLASPARTASE

(Clostridium
tetanomorphum)
PF05034
(MAAL_N)
PF07476
(MAAL_C)
4 VAL A 239
LEU A 211
LEU A 204
ILE A 258
None
0.81A 4lzrA-1kczA:
undetectable
4lzrA-1kczA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkr 3-METHYLASPARTATE
AMMONIA-LYASE


(Citrobacter
amalonaticus)
PF05034
(MAAL_N)
PF07476
(MAAL_C)
4 VAL A 239
LEU A 211
LEU A 204
ILE A 258
None
0.89A 4lzrA-1kkrA:
undetectable
4lzrA-1kkrA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ks8 ENDO-B-1,4-GLUCANASE

(Nasutitermes
takasagoensis)
PF00759
(Glyco_hydro_9)
5 TRP A  74
LEU A 320
LEU A 322
TYR A 327
ILE A 313
None
1.50A 4lzrA-1ks8A:
undetectable
4lzrA-1ks8A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mbm CHYMOTRYPSIN-LIKE
SERINE PROTEASE


(Equine
arteritis virus)
PF05579
(Peptidase_S32)
4 VAL A 189
LEU A 193
ASP A 177
ILE A 178
None
0.88A 4lzrA-1mbmA:
undetectable
4lzrA-1mbmA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mr2 ADPR PYROPHOSPHATASE

(Mycobacterium
tuberculosis)
PF00293
(NUDIX)
4 VAL A  98
LEU A 100
LEU A  94
ILE A  57
None
0.85A 4lzrA-1mr2A:
undetectable
4lzrA-1mr2A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no5 HYPOTHETICAL PROTEIN
HI0073


(Haemophilus
influenzae)
PF01909
(NTP_transf_2)
4 VAL A  78
LEU A  49
LEU A  80
ILE A  20
None
0.92A 4lzrA-1no5A:
undetectable
4lzrA-1no5A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ohe CDC14B2 PHOSPHATASE

(Homo sapiens)
PF00782
(DSPc)
PF14671
(DSPn)
5 VAL A 312
LEU A 263
LEU A 324
ASP A 301
ILE A 302
None
1.19A 4lzrA-1oheA:
undetectable
4lzrA-1oheA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ose PORCINE
ALPHA-AMYLASE


(Sus scrofa)
PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
4 VAL A 210
LEU A 170
ASP A 197
ILE A 196
None
None
AC1  A 992 ( 3.3A)
None
0.84A 4lzrA-1oseA:
undetectable
4lzrA-1oseA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ouu HEMOGLOBIN I

(Oncorhynchus
mykiss)
PF00042
(Globin)
4 VAL A 126
LEU A 107
LEU A 110
ILE A  67
None
0.91A 4lzrA-1ouuA:
undetectable
4lzrA-1ouuA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1q SULFOTRANSFERASE
FAMILY, CYTOSOLIC,
2B, MEMBER 1 ISOFORM
A


(Homo sapiens)
PF00685
(Sulfotransfer_1)
4 VAL A 225
LEU A 222
LEU A 217
ILE A 209
None
0.87A 4lzrA-1q1qA:
undetectable
4lzrA-1q1qA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5m PROSTAGLANDIN-E2
9-REDUCTASE


(Oryctolagus
cuniculus)
PF00248
(Aldo_ket_red)
4 LEU A 108
LEU A 106
ASP A  50
ILE A  49
None
None
NDP  A1003 (-3.7A)
None
0.89A 4lzrA-1q5mA:
undetectable
4lzrA-1q5mA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgj PEROXIDASE N

(Arabidopsis
thaliana)
PF00141
(peroxidase)
4 VAL A  22
LEU A  36
ASP A  96
ILE A  97
None
0.86A 4lzrA-1qgjA:
undetectable
4lzrA-1qgjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgj PEROXIDASE N

(Arabidopsis
thaliana)
PF00141
(peroxidase)
5 VAL A 259
LEU A 233
LEU A 232
TYR A 228
ASP A 225
None
None
None
None
CA  A2002 (-2.9A)
1.47A 4lzrA-1qgjA:
undetectable
4lzrA-1qgjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus)
PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C)
4 VAL A  54
LEU A  61
LEU A  58
ASP A 223
None
0.92A 4lzrA-1qhoA:
undetectable
4lzrA-1qhoA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwk ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1


(Caenorhabditis
elegans)
PF00248
(Aldo_ket_red)
4 LEU A  65
LEU A  66
ASP A 109
ILE A  78
None
0.90A 4lzrA-1qwkA:
undetectable
4lzrA-1qwkA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r3f TRNA PSEUDOURIDINE
SYNTHASE B


(Escherichia
coli)
PF01509
(TruB_N)
PF09157
(TruB-C_2)
PF16198
(TruB_C_2)
4 LEU A 216
LEU A 219
TYR A  36
ILE A  57
None
0.82A 4lzrA-1r3fA:
undetectable
4lzrA-1r3fA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r47 ALPHA-GALACTOSIDASE
A


(Homo sapiens)
PF16499
(Melibiase_2)
PF17450
(Melibiase_2_C)
4 VAL A 351
LEU A 415
LEU A 417
ILE A 367
None
0.91A 4lzrA-1r47A:
undetectable
4lzrA-1r47A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9u PUTATIVE COMPONENT
OF ANAEROBIC
DEHYDROGENASES


(Salmonella
enterica)
PF02613
(Nitrate_red_del)
5 VAL A  56
LEU A 181
LEU A 184
ASP A 164
ILE A 167
None
1.39A 4lzrA-1s9uA:
2.4
4lzrA-1s9uA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbp SULFATE-BINDING
PROTEIN


(Salmonella
enterica)
PF13531
(SBP_bac_11)
5 LEU A 243
LEU A 246
TYR A  20
ASN A  21
ILE A  38
None
1.44A 4lzrA-1sbpA:
undetectable
4lzrA-1sbpA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sch PEANUT PEROXIDASE,
MAJOR CATIONIC
ISOZYME


(Arachis
hypogaea)
PF00141
(peroxidase)
4 VAL A  22
LEU A  36
ASP A  99
ILE A 100
None
0.89A 4lzrA-1schA:
undetectable
4lzrA-1schA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1slj RIBONUCLEASE E

(Escherichia
coli)
PF00575
(S1)
5 VAL A  58
LEU A 116
LEU A  68
TYR A  77
ILE A 101
None
1.20A 4lzrA-1sljA:
undetectable
4lzrA-1sljA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1snn 3,4-DIHYDROXY-2-BUTA
NONE 4-PHOSPHATE
SYNTHASE


(Methanocaldococcus
jannaschii)
PF00926
(DHBP_synthase)
4 VAL A   4
LEU A 171
LEU A 174
ILE A 217
None
0.81A 4lzrA-1snnA:
undetectable
4lzrA-1snnA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uiy ENOYL-COA HYDRATASE

(Thermus
thermophilus)
PF00378
(ECH_1)
4 VAL A 164
LEU A 172
LEU A 174
TYR A 129
None
0.91A 4lzrA-1uiyA:
undetectable
4lzrA-1uiyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4n 271AA LONG
HYPOTHETICAL
5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE


(Sulfurisphaera
tokodaii)
PF01048
(PNP_UDP_1)
4 LEU A  49
LEU A  25
TYR A  20
ILE A  13
None
0.90A 4lzrA-1v4nA:
undetectable
4lzrA-1v4nA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8g HYPOTHETICAL UPF0001
PROTEIN YGGS


(Escherichia
coli)
PF01168
(Ala_racemase_N)
4 VAL A 152
LEU A 155
LEU A 158
ILE A 108
None
None
None
ICT  A1230 ( 4.2A)
0.81A 4lzrA-1w8gA:
undetectable
4lzrA-1w8gA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x3l HYPOTHETICAL PROTEIN
PH0495


(Pyrococcus
horikoshii)
PF05161
(MOFRL)
PF13660
(DUF4147)
4 LEU A 192
LEU A 128
ASP A  69
ILE A  70
None
0.78A 4lzrA-1x3lA:
undetectable
4lzrA-1x3lA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE


(Salmonella
enterica)
PF04223
(CitF)
4 VAL A 433
LEU A 449
LEU A 453
ILE A 258
None
0.82A 4lzrA-1xr4A:
undetectable
4lzrA-1xr4A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yfy 3-HYDROXYANTHRANILAT
E-3,4-DIOXYGENASE


(Cupriavidus
metallidurans)
PF06052
(3-HAO)
4 TRP A  31
VAL A  40
LEU A 107
LEU A  62
None
0.85A 4lzrA-1yfyA:
undetectable
4lzrA-1yfyA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytm PHOSPHOENOLPYRUVATE
CARBOXYKINASE [ATP]


(Anaerobiospirillum
succiniciproducens)
PF01293
(PEPCK_ATP)
4 VAL A 170
LEU A 176
LEU A 178
ILE A 194
None
0.86A 4lzrA-1ytmA:
undetectable
4lzrA-1ytmA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a6q ANTITOXIN YEFM

(Escherichia
coli)
PF02604
(PhdYeFM_antitox)
4 LEU A  63
LEU A  64
ASP A  78
ILE A  77
None
0.78A 4lzrA-2a6qA:
undetectable
4lzrA-2a6qA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b7h HEMOGLOBIN ALPHA
CHAIN


(Cerdocyon thous)
PF00042
(Globin)
4 LEU A 109
LEU A 106
ASP A   6
ILE A  10
None
0.79A 4lzrA-2b7hA:
undetectable
4lzrA-2b7hA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bmb FOLIC ACID SYNTHESIS
PROTEIN FOL1


(Saccharomyces
cerevisiae)
PF00809
(Pterin_bind)
PF01288
(HPPK)
5 TRP A 750
VAL A 395
LEU A 370
LEU A 362
ILE A 355
None
1.47A 4lzrA-2bmbA:
undetectable
4lzrA-2bmbA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bqx INORGANIC
PYROPHOSPHATASE


(Helicobacter
pylori)
PF00719
(Pyrophosphatase)
4 LEU A  73
LEU A 107
ASP A 123
ILE A 122
None
0.86A 4lzrA-2bqxA:
undetectable
4lzrA-2bqxA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c2y METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE-METHEN
YLTETRAHYDROFOLATE
CYCLOHYDROLASE


(Mycobacterium
tuberculosis)
PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C)
4 LEU A 100
LEU A 104
ASN A  79
ILE A  82
None
0.92A 4lzrA-2c2yA:
undetectable
4lzrA-2c2yA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cb1 O-ACETYL HOMOSERINE
SULFHYDRYLASE


(Thermus
thermophilus)
PF01053
(Cys_Met_Meta_PP)
4 VAL A 389
LEU A 333
LEU A 335
ILE A 348
None
0.82A 4lzrA-2cb1A:
undetectable
4lzrA-2cb1A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cg9 ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82


(Saccharomyces
cerevisiae)
PF00183
(HSP90)
PF02518
(HATPase_c)
4 VAL A 136
LEU A  89
LEU A  93
ASP A  40
None
None
None
ATP  A1678 ( 4.9A)
0.84A 4lzrA-2cg9A:
undetectable
4lzrA-2cg9A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dcq PUTATIVE PROTEIN
AT4G01050


(Arabidopsis
thaliana)
no annotation 5 VAL A  94
LEU A  62
LEU A  65
ASP A  26
ILE A  27
None
1.35A 4lzrA-2dcqA:
undetectable
4lzrA-2dcqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dld D-LACTATE
DEHYDROGENASE


(Lactobacillus
helveticus)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
4 VAL A  52
LEU A  36
ASN A  83
ILE A  84
None
0.90A 4lzrA-2dldA:
undetectable
4lzrA-2dldA:
16.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A  31
VAL A  37
LEU A  42
LEU A  44
TYR A  89
ASN A  90
ILE A  96
None
0.63A 4lzrA-2dvrA:
20.2
4lzrA-2dvrA:
67.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
6 TRP A  31
VAL A  37
TYR A  89
ASN A  90
ASP A  94
ILE A  96
None
0.64A 4lzrA-2dvrA:
20.2
4lzrA-2dvrA:
67.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dvr BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
5 VAL A  37
LEU A  42
ASN A  90
ASP A  94
ILE A  96
None
1.26A 4lzrA-2dvrA:
20.2
4lzrA-2dvrA:
67.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4


(Homo sapiens)
PF00248
(Aldo_ket_red)
4 LEU A 108
LEU A 106
ASP A  50
ILE A  49
None
None
NAP  A1001 (-3.7A)
None
0.88A 4lzrA-2fvlA:
undetectable
4lzrA-2fvlA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g37 PROLINE
DEHYDROGENASE/DELTA-
1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE


(Thermus
thermophilus)
PF01619
(Pro_dh)
4 VAL A 119
LEU A 116
LEU A 103
ASP A  61
None
0.90A 4lzrA-2g37A:
undetectable
4lzrA-2g37A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gep SULFITE REDUCTASE
HEMOPROTEIN


(Escherichia
coli)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
5 VAL A 491
LEU A 505
LEU A 503
ASP A 532
ILE A 535
None
1.34A 4lzrA-2gepA:
undetectable
4lzrA-2gepA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnp TRANSCRIPTIONAL
REGULATOR


(Streptococcus
pneumoniae)
PF04198
(Sugar-bind)
4 VAL A 208
LEU A 141
ASP A 204
ILE A 205
None
0.86A 4lzrA-2gnpA:
undetectable
4lzrA-2gnpA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gs9 HYPOTHETICAL PROTEIN
TT1324


(Thermus
thermophilus)
PF08241
(Methyltransf_11)
4 VAL A 131
LEU A 166
LEU A 170
ASP A 111
None
0.87A 4lzrA-2gs9A:
undetectable
4lzrA-2gs9A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hh9 THIAMIN
PYROPHOSPHOKINASE


(Candida
albicans)
PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding)
4 VAL A 319
LEU A 268
LEU A 270
ILE A 200
None
0.85A 4lzrA-2hh9A:
undetectable
4lzrA-2hh9A:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H


(Human
immunodeficiency
virus 1)
PF00075
(RNase_H)
PF00078
(RVT_1)
PF06815
(RVT_connect)
PF06817
(RVT_thumb)
5 VAL A 531
LEU A 533
LEU A 429
TYR A 427
ILE A 521
None
1.21A 4lzrA-2hnzA:
1.4
4lzrA-2hnzA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ho9 CHEMOTAXIS PROTEIN
CHEW


(Escherichia
coli)
PF01584
(CheW)
4 VAL A 102
LEU A  71
TYR A  29
ILE A  31
None
0.88A 4lzrA-2ho9A:
undetectable
4lzrA-2ho9A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipj ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2


(Homo sapiens)
PF00248
(Aldo_ket_red)
4 LEU A 108
LEU A 106
ASP A  50
ILE A  49
None
None
NAP  A   1 (-3.7A)
None
0.91A 4lzrA-2ipjA:
undetectable
4lzrA-2ipjA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2it1 362AA LONG
HYPOTHETICAL
MALTOSE/MALTODEXTRIN
TRANSPORT
ATP-BINDING PROTEIN


(Pyrococcus
horikoshii)
PF00005
(ABC_tran)
4 VAL A 172
LEU A 161
LEU A 164
ILE A 144
None
0.80A 4lzrA-2it1A:
undetectable
4lzrA-2it1A:
16.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Mus musculus)
PF00439
(Bromodomain)
6 LEU A  68
LEU A  70
TYR A 115
ASN A 116
ASP A 120
ILE A 122
None
0.84A 4lzrA-2l5eA:
17.5
4lzrA-2l5eA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Mus musculus)
PF00439
(Bromodomain)
6 TRP A  57
LEU A  68
LEU A  70
TYR A 115
ASN A 116
ILE A 122
None
0.99A 4lzrA-2l5eA:
17.5
4lzrA-2l5eA:
74.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2l5e BROMODOMAIN-CONTAINI
NG PROTEIN 3


(Mus musculus)
PF00439
(Bromodomain)
6 VAL A  63
LEU A  68
LEU A  70
TYR A 115
ASN A 116
ASP A 120
None
1.10A 4lzrA-2l5eA:
17.5
4lzrA-2l5eA:
74.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbg RALA-BINDING PROTEIN
1


(Homo sapiens)
PF00620
(RhoGAP)
4 VAL A 350
LEU A 278
LEU A 279
ILE A 322
None
0.78A 4lzrA-2mbgA:
undetectable
4lzrA-2mbgA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nxp TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 5


(Homo sapiens)
PF04494
(TFIID_NTD2)
4 LEU A 236
LEU A 239
ASP A 340
ILE A 341
None
0.86A 4lzrA-2nxpA:
undetectable
4lzrA-2nxpA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ocf ESTROGEN RECEPTOR

(Homo sapiens)
PF00104
(Hormone_recep)
4 LEU A 507
LEU A 508
ASP A 484
ILE A 487
None
0.85A 4lzrA-2ocfA:
undetectable
4lzrA-2ocfA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2omv INTERNALIN-A

(Listeria
monocytogenes)
PF08191
(LRR_adjacent)
PF12354
(Internalin_N)
PF12799
(LRR_4)
4 VAL A 357
LEU A 344
LEU A 366
ILE A 351
None
0.87A 4lzrA-2omvA:
undetectable
4lzrA-2omvA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owo DNA LIGASE

(Escherichia
coli)
PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5)
4 VAL A 444
LEU A 474
LEU A 500
ILE A 458
None
0.91A 4lzrA-2owoA:
undetectable
4lzrA-2owoA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p2m ACETYL-COENZYME A
SYNTHETASE


(Salmonella
enterica)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N)
4 LEU A 317
LEU A 321
TYR A 110
ILE A 108
None
0.88A 4lzrA-2p2mA:
undetectable
4lzrA-2p2mA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5z TYPE VI SECRETION
SYSTEM COMPONENT


(Escherichia
coli)
PF05954
(Phage_GPD)
5 VAL X 173
LEU X 170
LEU X 115
ASP X 147
ILE X 197
None
1.23A 4lzrA-2p5zX:
undetectable
4lzrA-2p5zX:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p8u HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
CYTOPLASMIC


(Homo sapiens)
PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C)
4 VAL A 156
LEU A 108
ASP A  64
ILE A  65
None
0.86A 4lzrA-2p8uA:
undetectable
4lzrA-2p8uA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfi CHLORIDE CHANNEL
PROTEIN CLC-KA


(Homo sapiens)
PF00571
(CBS)
4 VAL A 594
LEU A 558
ASP A 620
ILE A 621
None
0.89A 4lzrA-2pfiA:
undetectable
4lzrA-2pfiA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pp3 L-TALARATE/GALACTARA
TE DEHYDRATASE


(Salmonella
enterica)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
4 LEU A 154
LEU A 155
ASP A 109
ILE A 108
None
0.91A 4lzrA-2pp3A:
undetectable
4lzrA-2pp3A:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q3g PDZ AND LIM DOMAIN
PROTEIN 7


(Homo sapiens)
PF00595
(PDZ)
4 LEU A  77
LEU A   8
ASP A  48
ILE A  30
None
0.85A 4lzrA-2q3gA:
undetectable
4lzrA-2q3gA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r0v CHROMATIN
STRUCTURE-REMODELING
COMPLEX PROTEIN RSC4


(Saccharomyces
cerevisiae)
PF00439
(Bromodomain)
4 VAL A 217
LEU A 222
ASN A 268
ILE A 274
None
0.88A 4lzrA-2r0vA:
12.9
4lzrA-2r0vA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rir DIPICOLINATE
SYNTHASE, A CHAIN


(Bacillus
subtilis)
PF01262
(AlaDh_PNT_C)
PF16924
(DpaA_N)
4 VAL A 210
LEU A 206
ASP A 241
ILE A 239
None
0.85A 4lzrA-2rirA:
undetectable
4lzrA-2rirA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ux7 PSEUDOAZURIN

(Achromobacter
cycloclastes)
PF00127
(Copper-bind)
4 VAL A  87
LEU A 120
LEU A 117
ASN A  96
None
0.91A 4lzrA-2ux7A:
undetectable
4lzrA-2ux7A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzc PDZ AND LIM DOMAIN 5

(Homo sapiens)
PF00595
(PDZ)
4 LEU A  77
LEU A   8
ASP A  48
ILE A  30
None
0.91A 4lzrA-2uzcA:
undetectable
4lzrA-2uzcA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vgq SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,MITOCHONDRIA
L
ANTIVIRAL-SIGNALING
PROTEIN


(Escherichia
coli;
Homo sapiens)
PF13416
(SBP_bac_8)
PF16739
(CARD_2)
4 VAL A 391
LEU A 453
LEU A 445
ILE A 381
None
0.83A 4lzrA-2vgqA:
undetectable
4lzrA-2vgqA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpq ACETYL-COA
CARBOXYLASE


(Staphylococcus
aureus)
PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
5 VAL A 213
LEU A 308
LEU A 311
ASP A 327
ILE A 328
None
1.39A 4lzrA-2vpqA:
undetectable
4lzrA-2vpqA:
13.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2wp1 BROMODOMAIN
TESTIS-SPECIFIC
PROTEIN


(Mus musculus)
PF00439
(Bromodomain)
6 TRP A 292
VAL A 298
LEU A 303
LEU A 305
TYR A 350
ASN A 351
None
0.78A 4lzrA-2wp1A:
16.6
4lzrA-2wp1A:
38.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wu5 SUCCINATE
DEHYDROGENASE
FLAVOPROTEIN SUBUNIT


(Escherichia
coli)
PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C)
4 VAL A 190
LEU A 183
LEU A 167
ASN A 445
None
0.86A 4lzrA-2wu5A:
undetectable
4lzrA-2wu5A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wya HYDROXYMETHYLGLUTARY
L-COA SYNTHASE,
MITOCHONDRIAL


(Homo sapiens)
PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C)
4 VAL A 193
LEU A 145
ASP A 101
ILE A 102
None
0.82A 4lzrA-2wyaA:
undetectable
4lzrA-2wyaA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x40 BETA-GLUCOSIDASE

(Thermotoga
neapolitana)
PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like)
4 LEU A  11
LEU A   8
ASP A 258
ILE A 300
None
0.88A 4lzrA-2x40A:
undetectable
4lzrA-2x40A:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3w SPINDLE ASSEMBLY
ABNORMAL PROTEIN 6
HOMOLOG


(Danio rerio)
PF16531
(SAS-6_N)
4 VAL A  28
LEU A  10
ASP A  89
ILE A  88
None
0.91A 4lzrA-2y3wA:
undetectable
4lzrA-2y3wA:
22.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2yek BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
6 TRP A  97
VAL A 103
LEU A 108
LEU A 110
TYR A 155
ILE A 162
None
EAM  A1188 (-4.4A)
EAM  A1188 ( 3.8A)
EAM  A1188 (-4.5A)
None
EAM  A1188 (-3.8A)
0.56A 4lzrA-2yekA:
20.2
4lzrA-2yekA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2yek BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
7 TRP A  97
VAL A 103
LEU A 110
TYR A 155
ASN A 156
ASP A 160
ILE A 162
None
EAM  A1188 (-4.4A)
EAM  A1188 (-4.5A)
None
EAM  A1188 (-3.2A)
None
EAM  A1188 (-3.8A)
0.61A 4lzrA-2yekA:
20.2
4lzrA-2yekA:
66.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2yek BROMODOMAIN-CONTAINI
NG PROTEIN 2


(Homo sapiens)
PF00439
(Bromodomain)
5 VAL A 103
LEU A 108
ASN A 156
ASP A 160
ILE A 162
EAM  A1188 (-4.4A)
EAM  A1188 ( 3.8A)
EAM  A1188 (-3.2A)
None
EAM  A1188 (-3.8A)
1.11A 4lzrA-2yekA:
20.2
4lzrA-2yekA:
66.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yvx MG2+ TRANSPORTER
MGTE


(Thermus
thermophilus)
PF00571
(CBS)
PF01769
(MgtE)
PF03448
(MgtE_N)
5 VAL A 174
LEU A 180
LEU A 239
TYR A 142
ILE A 171
None
1.39A 4lzrA-2yvxA:
undetectable
4lzrA-2yvxA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywa HYPOTHETICAL PROTEIN
TTHA0048


(Thermus
thermophilus)
PF08780
(NTase_sub_bind)
5 LEU A  11
LEU A  15
TYR A  98
ASP A  25
ILE A  28
None
1.24A 4lzrA-2ywaA:
undetectable
4lzrA-2ywaA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z51 NIFU-LIKE PROTEIN 2,
CHLOROPLAST


(Arabidopsis
thaliana)
PF01106
(NifU)
4 VAL A  39
LEU A  29
LEU A  13
ILE A  70
None
0.89A 4lzrA-2z51A:
undetectable
4lzrA-2z51A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5x AMINE OXIDASE
[FLAVIN-CONTAINING]
A


(Homo sapiens)
PF01593
(Amino_oxidase)
5 VAL A  37
LEU A 460
LEU A 463
TYR A 268
ILE A 270
None
1.40A 4lzrA-2z5xA:
undetectable
4lzrA-2z5xA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z8u TATA-BOX-BINDING
PROTEIN


(Methanocaldococcus
jannaschii)
PF00352
(TBP)
4 VAL A  25
LEU A  42
LEU A  22
ILE A  16
None
0.88A 4lzrA-2z8uA:
undetectable
4lzrA-2z8uA:
19.90