SIMILAR PATTERNS OF AMINO ACIDS FOR 4LVC_C_ADNC501_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddk | IMP-1 METALLOBETA-LACTAMASE (Pseudomonasaeruginosa) |
PF00753(Lactamase_B) | 4 | GLN A 212THR A 209THR A 140HIS A 77 | NoneNoneNone ZN A 500 (-3.4A) | 1.14A | 4lvcC-1ddkA:2.7 | 4lvcC-1ddkA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | GLN B 342THR B 343THR B 251LEU B 318 | None | 1.11A | 4lvcC-1e9yB:2.2 | 4lvcC-1e9yB:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ems | NIT-FRAGILEHISTIDINE TRIADFUSION PROTEIN (Caenorhabditiselegans) |
PF00795(CN_hydrolase)PF01230(HIT) | 4 | GLN A 250THR A 199HIS A 203LEU A 207 | None | 1.38A | 4lvcC-1emsA:undetectable | 4lvcC-1emsA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnx | BETA-GLUCOSIDASE (Streptomycessp.) |
PF00232(Glyco_hydro_1) | 4 | THR A 382THR A 175HIS A 213LEU A 301 | None | 1.31A | 4lvcC-1gnxA:undetectable | 4lvcC-1gnxA:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iie | PROTEIN (HLA-DRANTIGENS ASSOCIATEDINVARIANT CHAIN) (Homo sapiens) |
PF08831(MHCassoc_trimer) | 4 | GLN A 131THR A 156HIS A 152LEU A 142 | None | 1.04A | 4lvcC-1iieA:undetectable | 4lvcC-1iieA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l4i | SFAE PROTEIN (Escherichiacoli) |
PF00345(PapD_N)PF02753(PapD_C) | 4 | GLN A 170THR A 146THR A 151LEU A 114 | None | 1.34A | 4lvcC-1l4iA:undetectable | 4lvcC-1l4iA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ml4 | ASPARTATETRANSCARBAMOYLASE (Pyrococcusabyssi) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | GLN A 138THR A 137THR A 49LEU A 60 | PAL A 385 (-4.7A)NoneNoneNone | 1.38A | 4lvcC-1ml4A:2.2 | 4lvcC-1ml4A:23.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfd | N15 ALPHA-BETAT-CELL RECEPTOR (Mus musculus) |
PF07686(V-set)PF09291(DUF1968) | 4 | GLN A 5THR A 4THR A 30LEU A 66 | None | 1.27A | 4lvcC-1nfdA:undetectable | 4lvcC-1nfdA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q40 | MRNA EXPORT FACTORMEX67MRNA TRANSPORTREGULATOR MTR2 (Candidaalbicans) |
PF10429(Mtr2)no annotation | 4 | GLN B 398THR B 495HIS A 91LEU B 385 | None | 1.32A | 4lvcC-1q40B:undetectable | 4lvcC-1q40B:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujj | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA1 (Homo sapiens) |
PF00790(VHS) | 4 | GLN A 36THR A 9THR A 18LEU A 51 | None | 1.01A | 4lvcC-1ujjA:undetectable | 4lvcC-1ujjA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uun | MSPA (Mycolicibacteriumsmegmatis) |
PF09203(MspA) | 4 | THR A 176THR A 130HIS A 42LEU A 25 | None | 1.33A | 4lvcC-1uunA:undetectable | 4lvcC-1uunA:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vsl | PROTEIN (INTEGRASE) (Rous sarcomavirus) |
PF00665(rve) | 4 | GLN A 59THR A 120HIS A 142LEU A 135 | None | 1.25A | 4lvcC-1vslA:undetectable | 4lvcC-1vslA:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wd3 | ALPHA-L-ARABINOFURANOSIDASE B (Aspergilluskawachii) |
PF05270(AbfB)PF09206(ArabFuran-catal) | 4 | GLN A 103THR A 144THR A 37LEU A 52 | None | 1.19A | 4lvcC-1wd3A:undetectable | 4lvcC-1wd3A:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdn | GLUTAMINE BINDINGPROTEIN (Escherichiacoli) |
PF00497(SBP_bac_3) | 4 | GLN A 184THR A 118HIS A 156LEU A 90 | NoneGLN A 227 (-4.2A)GLN A 227 (-4.0A)None | 1.36A | 4lvcC-1wdnA:undetectable | 4lvcC-1wdnA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zgd | CHALCONE REDUCTASE (Medicago sativa) |
PF00248(Aldo_ket_red) | 4 | GLN A 17THR A 14THR A 259HIS A 51 | None | 1.34A | 4lvcC-1zgdA:undetectable | 4lvcC-1zgdA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a81 | CARB (Pectobacteriumcarotovorum) |
PF00378(ECH_1) | 4 | GLN A 220THR A 221THR A 148LEU A 91 | None | 1.12A | 4lvcC-2a81A:undetectable | 4lvcC-2a81A:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b39 | C3 (Bos taurus) |
PF00207(A2M)PF01759(NTR)PF01821(ANATO)PF01835(A2M_N)PF07677(A2M_recep)PF07678(A2M_comp)PF07703(A2M_N_2)PF10569(Thiol-ester_cl) | 4 | GLN A1126THR A1398THR A1268LEU A1483 | None | 1.37A | 4lvcC-2b39A:undetectable | 4lvcC-2b39A:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpw | GREEN FLUORESCENTPROTEIN (Clytia gregaria) |
PF01353(GFP) | 4 | GLN A 89THR A 88HIS A 200LEU A 202 | None | 1.17A | 4lvcC-2hpwA:undetectable | 4lvcC-2hpwA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hro | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Staphylococcuscarnosus) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 4 | GLN A 510THR A 511THR A 454LEU A 521 | None | 1.13A | 4lvcC-2hroA:undetectable | 4lvcC-2hroA:23.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ice | COMPLEMENT C3 BETACHAIN (Homo sapiens) |
PF01835(A2M_N)PF07703(A2M_N_2) | 4 | GLN A 631THR A 632THR A 514HIS A 25 | None | 1.00A | 4lvcC-2iceA:undetectable | 4lvcC-2iceA:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nvv | ACETYL-COAHYDROLASE/TRANSFERASE FAMILY PROTEIN (Porphyromonasgingivalis) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 4 | GLN A 333THR A 107THR A 383HIS A 414 | GLN A 333 ( 0.6A)THR A 107 ( 0.8A)THR A 383 ( 0.8A)HIS A 414 ( 1.0A) | 1.02A | 4lvcC-2nvvA:2.0 | 4lvcC-2nvvA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2puq | TISSUE FACTOR (Homo sapiens) |
PF01108(Tissue_fac)PF09294(Interfer-bind) | 4 | GLN T 190THR T 203THR T 106LEU T 143 | None | 1.32A | 4lvcC-2puqT:undetectable | 4lvcC-2puqT:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzu | PUTATIVE SULFATASEYIDJ (Bacteroidesfragilis) |
PF00884(Sulfatase) | 4 | GLN A 380THR A 378HIS A 164LEU A 109 | None | 0.98A | 4lvcC-2qzuA:undetectable | 4lvcC-2qzuA:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rk5 | PUTATIVE HEMOLYSIN (Streptococcusmutans) |
PF03471(CorC_HlyC) | 4 | GLN A 3THR A 19THR A 29LEU A 70 | None | 1.37A | 4lvcC-2rk5A:undetectable | 4lvcC-2rk5A:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v9u | MSPA (Mycolicibacteriumsmegmatis) |
PF09203(MspA) | 4 | THR A 176THR A 130HIS A 42LEU A 25 | THR A 176 ( 0.8A)THR A 130 ( 0.8A)HIS A 42 ( 1.0A)LEU A 25 ( 0.5A) | 1.30A | 4lvcC-2v9uA:undetectable | 4lvcC-2v9uA:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsk | HEMAGGLUTININ-NEURAMINIDASE (Hendrahenipavirus) |
PF00423(HN) | 4 | GLN A 559THR A 507THR A 563LEU A 551 | None | 1.26A | 4lvcC-2vskA:undetectable | 4lvcC-2vskA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww2 | ALPHA-1,2-MANNOSIDASE (Bacteroidesthetaiotaomicron) |
PF07971(Glyco_hydro_92) | 4 | GLN A 304THR A 652HIS A 603LEU A 635 | GOL A 801 (-2.8A)NoneNoneNone | 1.30A | 4lvcC-2ww2A:undetectable | 4lvcC-2ww2A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xt0 | HALOALKANEDEHALOGENASE (Plesiocystispacifica) |
PF00561(Abhydrolase_1) | 4 | GLN A 236THR A 235THR A 241LEU A 130 | None | 1.37A | 4lvcC-2xt0A:undetectable | 4lvcC-2xt0A:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aeu | LIGHT-INDEPENDENTPROTOCHLOROPHYLLIDEREDUCTASE SUBUNIT N (Rhodobactercapsulatus) |
PF00148(Oxidored_nitro) | 4 | THR A 348THR A 368HIS A 360LEU A 357 | None | 1.35A | 4lvcC-3aeuA:undetectable | 4lvcC-3aeuA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3any | ETHANOLAMINEAMMONIA-LYASE HEAVYCHAIN (Escherichiacoli) |
PF06751(EutB) | 4 | GLN A 405THR A 366THR A 325LEU A 379 | None | 1.16A | 4lvcC-3anyA:undetectable | 4lvcC-3anyA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2y | METALLOPEPTIDASECONTAININGCO-CATALYTICMETALLOACTIVE SITE (Shewanelladenitrificans) |
PF04952(AstE_AspA) | 4 | GLN A 186THR A 187HIS A 269LEU A 240 | None | 1.36A | 4lvcC-3b2yA:undetectable | 4lvcC-3b2yA:20.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 73THR A 74THR A 219HIS A 363LEU A 407 | ADN A 500 (-3.6A)ADN A 500 (-4.5A)NAD A 550 ( 2.8A)ADN A 500 ( 3.7A)NAD A 550 (-4.2A) | 0.61A | 4lvcC-3ce6A:61.0 | 4lvcC-3ce6A:58.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0m | PEPTIDE METHIONINESULFOXIDE REDUCTASEMSRA/MSRB 1 (Streptococcuspneumoniae) |
PF01625(PMSR)PF01641(SelR) | 4 | GLN A 35THR A 47THR A 52LEU A 128 | None | 1.29A | 4lvcC-3e0mA:undetectable | 4lvcC-3e0mA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eeg | 2-ISOPROPYLMALATESYNTHASE (Cytophagahutchinsonii) |
PF00682(HMGL-like) | 4 | THR A 211THR A 259HIS A 263LEU A 266 | None | 1.16A | 4lvcC-3eegA:undetectable | 4lvcC-3eegA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo7 | PUTATIVENITROREDUCTASE (Trichormusvariabilis) |
PF00881(Nitroreductase) | 4 | GLN A 403THR A 312HIS A 436LEU A 462 | None | 1.34A | 4lvcC-3eo7A:undetectable | 4lvcC-3eo7A:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 4 | GLN A 292THR A 291THR A 337LEU A 332 | None | 0.85A | 4lvcC-3eqnA:undetectable | 4lvcC-3eqnA:22.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156HIS A 300LEU A 343 | ADN A 438 (-3.8A)ADN A 438 (-4.6A)NAD A 439 ( 3.0A)ADN A 438 ( 4.0A)NAD A 439 ( 4.0A) | 0.58A | 4lvcC-3g1uA:57.3 | 4lvcC-3g1uA:60.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 200HIS A 344LEU A 385 | RAB A 602 (-3.9A)RAB A 602 (-4.5A)NAD A 601 ( 2.9A)RAB A 602 ( 3.5A)NAD A 601 ( 4.1A) | 0.50A | 4lvcC-3glqA:61.5 | 4lvcC-3glqA:65.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156HIS A 300LEU A 343 | ADN A 439 (-3.6A)ADN A 439 (-4.7A)NAD A 438 (-3.8A)NoneNAD A 438 (-4.0A) | 0.44A | 4lvcC-3h9uA:57.8 | 4lvcC-3h9uA:58.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ibj | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I)PF01590(GAF)PF13185(GAF_2) | 4 | GLN A 875THR A 805HIS A 773LEU A 780 | None | 1.21A | 4lvcC-3ibjA:undetectable | 4lvcC-3ibjA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iie | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Yersiniapseudotuberculosis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 4 | GLN A 329THR A 130HIS A 153LEU A 238 | None | 1.38A | 4lvcC-3iieA:6.3 | 4lvcC-3iieA:22.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j3i | CAPSID PROTEIN (Penicilliumchrysogenumvirus) |
no annotation | 4 | GLN A 199THR A 317HIS A 260LEU A 264 | None | 1.33A | 4lvcC-3j3iA:undetectable | 4lvcC-3j3iA:18.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jts | MHC CLASS IMAMU-A*02 (Macaca mulatta) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 218THR A 216THR A 187LEU A 266 | None | 1.34A | 4lvcC-3jtsA:undetectable | 4lvcC-3jtsA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm6 | STAGE V SPORULATIONPROTEIN AD (Bacillussubtilis) |
PF07451(SpoVAD) | 4 | GLN A 7THR A 186THR A 232LEU A 247 | None | 1.34A | 4lvcC-3lm6A:undetectable | 4lvcC-3lm6A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lma | STAGE V SPORULATIONPROTEIN AD (SPOVAD) (Bacilluslicheniformis) |
PF07451(SpoVAD) | 4 | GLN A 7THR A 186THR A 232LEU A 247 | None | 1.29A | 4lvcC-3lmaA:undetectable | 4lvcC-3lmaA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mr1 | METHIONINEAMINOPEPTIDASE (Rickettsiaprowazekii) |
PF00557(Peptidase_M24) | 4 | THR A 28THR A 106HIS A 234LEU A 248 | None | 1.29A | 4lvcC-3mr1A:undetectable | 4lvcC-3mr1A:21.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 59THR A 60THR A 193HIS A 337LEU A 378 | K A 2 ( 3.3A)ADN A 500 (-4.6A)NAD A 550 ( 3.0A)ADN A 500 ( 3.6A)NAD A 550 (-4.3A) | 0.50A | 4lvcC-3n58A:62.6 | 4lvcC-3n58A:69.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obw | PROTEIN PELOTAHOMOLOG (Sulfolobussolfataricus) |
PF03463(eRF1_1)PF03465(eRF1_3) | 4 | THR A 223THR A 40HIS A 93LEU A 59 | None | 1.21A | 4lvcC-3obwA:undetectable | 4lvcC-3obwA:22.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 206HIS A 350LEU A 395 | ADE A 506 (-3.8A)ADE A 506 (-4.5A)NAD A 501 (-2.8A)NoneNAD A 501 (-4.2A) | 0.34A | 4lvcC-3oneA:57.8 | 4lvcC-3oneA:62.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pl1 | PYRAZINAMIDASE/NICOTINAMIDASE PNCA(PZASE) (Mycobacteriumtuberculosis) |
PF00857(Isochorismatase) | 4 | GLN A 141THR A 142THR A 160LEU A 172 | None | 1.35A | 4lvcC-3pl1A:3.2 | 4lvcC-3pl1A:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q4t | ACTIVIN RECEPTORTYPE-2A (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 248THR A 267HIS A 320LEU A 303 | NoneTAK A 2 (-3.5A)NoneNone | 1.34A | 4lvcC-3q4tA:undetectable | 4lvcC-3q4tA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qlt | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 2 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 4 | THR A 253THR A 227HIS A 201LEU A 233 | None | 1.18A | 4lvcC-3qltA:5.5 | 4lvcC-3qltA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2s | PUTATIVEPYRAZINAMIDASE/NICOTINAMIDASE (Streptococcusmutans) |
PF00857(Isochorismatase) | 4 | GLN A 150THR A 125THR A 140LEU A 173 | None | 1.39A | 4lvcC-3s2sA:3.5 | 4lvcC-3s2sA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3to3 | PETROBACTINBIOSYNTHESIS PROTEINASBB (Bacillusanthracis) |
PF04183(IucA_IucC)PF06276(FhuF) | 4 | GLN A 124THR A 125THR A 570LEU A 101 | None | 1.14A | 4lvcC-3to3A:undetectable | 4lvcC-3to3A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbo | GENOME POLYPROTEIN,CAPSID PROTEIN VP2 (Enterovirus A) |
PF00073(Rhv) | 4 | THR B 137THR B 298HIS B 187LEU B 291 | None | 1.38A | 4lvcC-3vboB:undetectable | 4lvcC-3vboB:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x27 | CUCUMOPINE SYNTHASE (Marinactinosporathermotolerans) |
no annotation | 4 | GLN A 168THR A 171THR A 263LEU A 219 | None | 1.32A | 4lvcC-3x27A:undetectable | 4lvcC-3x27A:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aij | TRANSCRIPTIONALREGULATOR SLYA (Yersiniapseudotuberculosis) |
PF01047(MarR) | 4 | GLN A 60THR A 32HIS A 33LEU A 70 | None | 1.29A | 4lvcC-4aijA:undetectable | 4lvcC-4aijA:15.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akm | LYSOSOME-ASSOCIATEDMEMBRANEGLYCOPROTEIN 3 (Homo sapiens) |
PF01299(Lamp) | 4 | GLN A 330THR A 331THR A 355LEU A 292 | None | 1.34A | 4lvcC-4akmA:undetectable | 4lvcC-4akmA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3h | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA190 (Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | THR A 594THR A 653HIS A 603LEU A 616 | None | 1.23A | 4lvcC-4c3hA:undetectable | 4lvcC-4c3hA:14.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnk | L-AMINO ACID OXIDASE (Streptococcuscristatus) |
PF03486(HI0933_like) | 4 | GLN A 156THR A 6THR A 348HIS A 389 | None | 1.18A | 4lvcC-4cnkA:undetectable | 4lvcC-4cnkA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4htz | CGMP-DEPENDENT3',5'-CYCLICPHOSPHODIESTERASE (Homo sapiens) |
PF00233(PDEase_I) | 4 | GLN A 875THR A 805HIS A 773LEU A 780 | None | 1.26A | 4lvcC-4htzA:undetectable | 4lvcC-4htzA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lcy | HLA CLASS IHISTOCOMPATIBILITYANTIGEN, B-46 ALPHACHAIN (Homo sapiens) |
PF00129(MHC_I)PF07654(C1-set) | 4 | GLN A 218THR A 216THR A 187LEU A 266 | NoneNone NA A 301 (-2.9A)None | 1.38A | 4lvcC-4lcyA:undetectable | 4lvcC-4lcyA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lry | PTS-DEPENDENTDIHYDROXYACETONEKINASE,DIHYDROXYACETONE-BINDING SUBUNIT DHAK (Escherichiacoli) |
PF02733(Dak1) | 4 | THR A 129THR A 153HIS A 60LEU A 69 | None | 1.23A | 4lvcC-4lryA:3.4 | 4lvcC-4lryA:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lwo | ARGININEN-METHYLTRANSFERASE,PUTATIVE (Trypanosomabrucei) |
no annotation | 4 | GLN B 321THR B 323HIS B 280LEU B 238 | None | 1.34A | 4lvcC-4lwoB:2.9 | 4lvcC-4lwoB:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0r | PUTATIVE GLYCOSIDEHYDROLASE (Bacteroidesvulgatus) |
PF13204(DUF4038)PF16586(DUF5060) | 4 | GLN A 404THR A 136HIS A 389LEU A 408 | None | 1.28A | 4lvcC-4n0rA:2.9 | 4lvcC-4n0rA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | GLN A 159THR A 229THR A 235HIS A 237 | None | 1.33A | 4lvcC-4n6kA:undetectable | 4lvcC-4n6kA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | GLN A 159THR A 229THR A 235LEU A 168 | None | 1.35A | 4lvcC-4n6kA:undetectable | 4lvcC-4n6kA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | THR A 229THR A 235HIS A 237LEU A 185 | None | 0.97A | 4lvcC-4n6kA:undetectable | 4lvcC-4n6kA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nq1 | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Legionellapneumophila) |
PF00701(DHDPS) | 4 | GLN A 111THR A 110THR A 81HIS A 120 | NoneNoneMRD A 301 ( 4.2A)MRD A 301 ( 4.8A) | 1.29A | 4lvcC-4nq1A:undetectable | 4lvcC-4nq1A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1e | DIHYDROPTEROATESYNTHASE DHPS (Desulfitobacteriumhafniense) |
PF00809(Pterin_bind) | 4 | GLN A 35THR A 194HIS A 159LEU A 95 | None | 1.03A | 4lvcC-4o1eA:2.2 | 4lvcC-4o1eA:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oo3 | HYPOTHETICAL PROTEIN (Parabacteroidesmerdae) |
PF01408(GFO_IDH_MocA)PF16490(Oxidoreduct_C) | 4 | GLN A 118THR A 174HIS A 419LEU A 50 | None | 1.14A | 4lvcC-4oo3A:undetectable | 4lvcC-4oo3A:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pcb | TRWC (Escherichiacoli) |
PF08751(TrwC) | 4 | GLN A 126THR A 189HIS A 4LEU A 84 | None | 1.32A | 4lvcC-4pcbA:undetectable | 4lvcC-4pcbA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qn3 | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | THR A 303THR A 207HIS A 202LEU A 9 | None | 1.21A | 4lvcC-4qn3A:undetectable | 4lvcC-4qn3A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk2 | PUTATIVE SUGAR ABCTRANSPORTER,SUBSTRATE-BINDINGPROTEIN (Rhizobium etli) |
PF01547(SBP_bac_1) | 4 | GLN A 274THR A 273HIS A 197LEU A 195 | None | 1.29A | 4lvcC-4rk2A:undetectable | 4lvcC-4rk2A:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tvm | CITRATE SYNTHASE (Mycobacteriumtuberculosis) |
PF00285(Citrate_synt) | 4 | GLN A 111THR A 195THR A 204LEU A 389 | None | 1.22A | 4lvcC-4tvmA:undetectable | 4lvcC-4tvmA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4txd | CSC2 (Thermofilumpendens) |
no annotation | 4 | GLN A 88THR A 85THR A 156LEU A 331 | None | 1.36A | 4lvcC-4txdA:undetectable | 4lvcC-4txdA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubq | BETA-LACTAMASE (Acinetobacterbaumannii) |
no annotation | 4 | GLN A 213THR A 210THR A 141HIS A 78 | NoneNoneNone ZN A 301 (-3.4A) | 1.12A | 4lvcC-4ubqA:3.3 | 4lvcC-4ubqA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4upk | PHOSPHONATEMONOESTER HYDROLASE (Ruegeriapomeroyi) |
PF00884(Sulfatase) | 4 | THR A 341THR A 209HIS A 207LEU A 61 | None | 1.13A | 4lvcC-4upkA:undetectable | 4lvcC-4upkA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxp | NS3-4 PROTEASE (Hepacivirus C) |
PF07652(Flavi_DEAD) | 4 | GLN A 434THR A 435THR A 430HIS A 369 | None | 1.29A | 4lvcC-4wxpA:undetectable | 4lvcC-4wxpA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yff | SERINE/THREONINE-PROTEIN KINASE TNNI3K (Homo sapiens) |
PF07714(Pkinase_Tyr) | 4 | GLN A 523THR A 539HIS A 586LEU A 577 | None4CV A 801 (-2.8A)NoneNone | 1.33A | 4lvcC-4yffA:undetectable | 4lvcC-4yffA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yvs | CAPSID PROTEIN VP0 (Enterovirus A) |
PF00073(Rhv) | 4 | THR C 68THR C 229HIS C 118LEU C 222 | None | 1.35A | 4lvcC-4yvsC:undetectable | 4lvcC-4yvsC:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aca | VP3 (Foot-and-mouthdisease virus) |
PF00073(Rhv) | 4 | GLN 3 156THR 3 88HIS 3 85LEU 3 104 | None | 1.30A | 4lvcC-5aca3:undetectable | 4lvcC-5aca3:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b3r | IMP-18 (Pseudomonasaeruginosa) |
no annotation | 4 | GLN A 230THR A 227THR A 158HIS A 95 | NoneNoneNone ZN A2001 ( 3.4A) | 1.13A | 4lvcC-5b3rA:2.9 | 4lvcC-5b3rA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dds | CRMG (Actinoalloteichussp. WH1-2216-6) |
PF00202(Aminotran_3) | 4 | GLN A 318THR A 319THR A 294LEU A 203 | PLP A 601 (-3.4A)NoneNoneNone | 1.31A | 4lvcC-5ddsA:undetectable | 4lvcC-5ddsA:23.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jri | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE (Synechocystissp. PCC 6803) |
no annotation | 4 | GLN A 282THR A 277THR A 131LEU A 262 | NoneNoneFAD A 401 (-4.0A)None | 1.35A | 4lvcC-5jriA:2.5 | 4lvcC-5jriA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kyu | PROTEIN TRANSPORTPROTEIN SEC24D (Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 4 | GLN B 563THR B 556HIS B 582LEU B 648 | None | 1.38A | 4lvcC-5kyuB:3.5 | 4lvcC-5kyuB:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lmc | ANAEROBIC NITRICOXIDE REDUCTASEFLAVORUBREDOXIN (Escherichiacoli) |
PF00258(Flavodoxin_1)PF00301(Rubredoxin)PF00753(Lactamase_B) | 4 | GLN A 190THR A 29HIS A 147LEU A 199 | NoneNoneFEO A 501 ( 3.4A)None | 1.03A | 4lvcC-5lmcA:undetectable | 4lvcC-5lmcA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lqd | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (Streptomycesvenezuelae) |
PF00982(Glyco_transf_20) | 4 | GLN A 151THR A 165HIS A 94LEU A 90 | None | 1.37A | 4lvcC-5lqdA:4.4 | 4lvcC-5lqdA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nci | LEUCINE HYDROXYLASE (Streptomycesmuensis) |
PF05721(PhyH) | 4 | GLN A 111THR A 227HIS A 92LEU A 122 | None | 1.12A | 4lvcC-5nciA:undetectable | 4lvcC-5nciA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swk | DE NOVO PROTEINBASED ON THEINHIBITORAMOEBIASIN-1E3 UBIQUITIN-PROTEINLIGASE MDM2 (Entamoebahistolytica;Homo sapiens) |
no annotation | 4 | GLN A 72THR C 85HIS A 96LEU C 94 | None | 1.02A | 4lvcC-5swkA:undetectable | 4lvcC-5swkA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w63 | APOPTOSIS REGULATORBAX (Ictaluruspunctatus) |
no annotation | 4 | GLN A 154THR A 54HIS A 55LEU A 21 | None | 1.35A | 4lvcC-5w63A:undetectable | 4lvcC-5w63A:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | GLN B1065THR B1090HIS B1025LEU B1026 | None | 1.35A | 4lvcC-5xogB:undetectable | 4lvcC-5xogB:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y0e | - (-) |
no annotation | 4 | GLN A 57THR A 53THR A 169LEU A 153 | None | 1.38A | 4lvcC-5y0eA:undetectable | 4lvcC-5y0eA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 62THR A 63THR A 162HIS A 306LEU A 349 | ADN A 501 (-3.8A)ADN A 501 (-4.5A)NAD A 500 ( 2.9A)ADN A 501 ( 3.7A)NAD A 500 ( 4.3A) | 0.59A | 4lvcC-6aphA:58.5 | 4lvcC-6aphA:60.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b67 | PROTEIN PHOSPHATASE1A (Homo sapiens) |
no annotation | 4 | GLN A 213THR A 128HIS A 62LEU A 191 | None | 1.15A | 4lvcC-6b67A:undetectable | 4lvcC-6b67A:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bog | RNAPOLYMERASE-ASSOCIATED PROTEIN RAPA (Escherichiacoli) |
no annotation | 4 | THR A 421THR A 313HIS A 324LEU A 417 | None | 1.26A | 4lvcC-6bogA:undetectable | 4lvcC-6bogA:11.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | GLN B 65THR B 66THR B 165HIS B 323LEU B 373 | K B 504 ( 3.0A)ADN B 502 (-4.6A)NAD B 501 ( 2.8A) ZN B 505 (-3.2A)NAD B 501 ( 3.9A) | 0.19A | 4lvcC-6f3mB:53.7 | 4lvcC-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 5 | GLN A 60THR A 61THR A 160HIS A 304LEU A 347 | NA A 503 ( 3.2A)ADN A 501 (-4.6A)NAD A 502 ( 2.8A)ADN A 501 ( 3.6A)NAD A 502 (-3.9A) | 0.13A | 4lvcC-6gbnA:58.5 | 4lvcC-6gbnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 7mdh | PROTEIN (MALATEDEHYDROGENASE) (Sorghum bicolor) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | GLN A 208THR A 198HIS A 229LEU A 385 | NoneNone ZN A 501 (-2.9A) ZN A 503 (-4.0A) | 1.28A | 4lvcC-7mdhA:5.7 | 4lvcC-7mdhA:23.05 |