SIMILAR PATTERNS OF AMINO ACIDS FOR 4LVC_B_ADNB501_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1avv | NEGATIVE FACTOR (Humanimmunodeficiencyvirus 1) |
PF00469(F-protein) | 4 | GLN A 118THR A 117LEU A 97LEU A 91 | None | 1.08A | 4lvcB-1avvA:undetectable | 4lvcB-1avvA:14.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ck7 | PROTEIN (GELATINASEA) (Homo sapiens) |
PF00040(fn2)PF00045(Hemopexin)PF00413(Peptidase_M10)PF01471(PG_binding_1) | 4 | GLN A 442THR A 155LEU A 420LEU A 433 | None | 1.01A | 4lvcB-1ck7A:undetectable | 4lvcB-1ck7A:22.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eak | 72 KDA TYPE IVCOLLAGENASE (Homo sapiens) |
PF00040(fn2)PF00413(Peptidase_M10)PF01471(PG_binding_1) | 4 | GLN A 442THR A 155LEU A 420LEU A 433 | None | 1.00A | 4lvcB-1eakA:undetectable | 4lvcB-1eakA:22.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ewr | DNA MISMATCH REPAIRPROTEIN MUTS (Thermusaquaticus) |
PF00488(MutS_V)PF05188(MutS_II)PF05190(MutS_IV)PF05192(MutS_III) | 4 | THR A 582THR A 678LEU A 705LEU A 708 | None | 1.09A | 4lvcB-1ewrA:undetectable | 4lvcB-1ewrA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfs | STROMELYSIN-1 (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | GLN A 243THR A 128LEU A 218LEU A 234 | NoneNoneL04 A 256 ( 4.7A)None | 1.00A | 4lvcB-1hfsA:undetectable | 4lvcB-1hfsA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyl | HYPODERMA LINEATUMCOLLAGENASE (Hypodermalineatum) |
PF00089(Trypsin) | 4 | GLN A 239THR A 242LEU A 209LEU A 123 | None | 1.07A | 4lvcB-1hylA:undetectable | 4lvcB-1hylA:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ozn | RETICULON 4 RECEPTOR (Homo sapiens) |
PF13855(LRR_8) | 4 | THR A 125THR A 173LEU A 161LEU A 137 | None | 1.11A | 4lvcB-1oznA:undetectable | 4lvcB-1oznA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qib | 72 KDA TYPE IVCOLLAGENASE (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | GLN A 243THR A 128LEU A 218LEU A 234 | None | 1.06A | 4lvcB-1qibA:undetectable | 4lvcB-1qibA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4n | AMYLOID BETAPRECURSORPROTEIN-BINDINGPROTEIN 1 (Homo sapiens) |
PF00899(ThiF) | 4 | GLN A 503THR A 129LEU A 46LEU A 49 | None | 1.09A | 4lvcB-1r4nA:2.2 | 4lvcB-1r4nA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1slm | STROMELYSIN-1 (Homo sapiens) |
PF00413(Peptidase_M10)PF01471(PG_binding_1) | 4 | GLN A 243THR A 128LEU A 218LEU A 234 | None | 0.99A | 4lvcB-1slmA:undetectable | 4lvcB-1slmA:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ujj | ADP-RIBOSYLATIONFACTOR BINDINGPROTEIN GGA1 (Homo sapiens) |
PF00790(VHS) | 4 | GLN A 36THR A 9THR A 18LEU A 51 | None | 1.04A | 4lvcB-1ujjA:undetectable | 4lvcB-1ujjA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vqu | ANTHRANILATEPHOSPHORIBOSYLTRANSFERASE 2 (Nostoc sp. PCC7120) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N) | 4 | GLN A 311THR A 307THR A 111LEU A 252 | None | 1.05A | 4lvcB-1vquA:2.8 | 4lvcB-1vquA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyr | RHO GUANINENUCLEOTIDE EXCHANGEFACTOR 6 (Homo sapiens) |
PF00307(CH) | 4 | THR A 114THR A 106LEU A 45LEU A 48 | None | 1.04A | 4lvcB-1wyrA:undetectable | 4lvcB-1wyrA:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xeb | HYPOTHETICAL PROTEINPA0115 (Pseudomonasaeruginosa) |
PF13673(Acetyltransf_10) | 4 | GLN A 38THR A 49LEU A 21LEU A 22 | None | 1.11A | 4lvcB-1xebA:undetectable | 4lvcB-1xebA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zdx | OUTER MEMBRANE USHERPROTEIN FIMD (Escherichiacoli) |
PF13954(PapC_N) | 4 | GLN A 117THR A 94LEU A 113LEU A 39 | None | 0.88A | 4lvcB-1zdxA:undetectable | 4lvcB-1zdxA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bp1 | AFLATOXIN B1ALDEHYDE REDUCTASEMEMBER 2 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | THR A 70THR A 45LEU A 131LEU A 94 | None | 1.03A | 4lvcB-2bp1A:undetectable | 4lvcB-2bp1A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ci6 | NG,NG-DIMETHYLARGININEDIMETHYLAMINOHYDROLASE 1 (Bos taurus) |
PF02274(Amidinotransf) | 4 | GLN A 60THR A 13LEU A 108LEU A 111 | None | 0.91A | 4lvcB-2ci6A:undetectable | 4lvcB-2ci6A:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e9f | ARGININOSUCCINATELYASE (Thermusthermophilus) |
PF00206(Lyase_1)PF14698(ASL_C2) | 4 | THR A 215THR A 206LEU A 51LEU A 46 | None | 1.11A | 4lvcB-2e9fA:undetectable | 4lvcB-2e9fA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exa | PENICILLIN-BINDINGPROTEIN 4 (Escherichiacoli) |
PF02113(Peptidase_S13) | 4 | GLN A 158THR A 157LEU A 178LEU A 244 | None | 1.03A | 4lvcB-2exaA:undetectable | 4lvcB-2exaA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g7z | CONSERVEDHYPOTHETICAL PROTEINSPY1493 (Streptococcuspyogenes) |
PF02645(DegV) | 4 | GLN A 122THR A 259LEU A 192LEU A 157 | NoneHXA A9136 ( 3.7A)NoneNone | 0.98A | 4lvcB-2g7zA:undetectable | 4lvcB-2g7zA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l8b | PROTEIN TRAI (Escherichiacoli) |
no annotation | 4 | GLN A 531THR A 504THR A 535LEU A 426 | None | 1.08A | 4lvcB-2l8bA:undetectable | 4lvcB-2l8bA:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nef | NEGATIVE FACTOR(F-PROTEIN) (Humanimmunodeficiencyvirus 1) |
PF00469(F-protein) | 4 | GLN A 118THR A 117LEU A 97LEU A 91 | None | 0.94A | 4lvcB-2nefA:undetectable | 4lvcB-2nefA:15.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ob1 | LEUCINE CARBOXYLMETHYLTRANSFERASE 1 (Saccharomycescerevisiae) |
PF04072(LCM) | 4 | GLN A 213THR A 182LEU A 203LEU A 204 | None | 1.03A | 4lvcB-2ob1A:2.9 | 4lvcB-2ob1A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv8 | FATTY ACID SYNTHASESUBUNIT BETA (FAS1) (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF01575(MaoC_dehydratas)PF08354(DUF1729)PF13452(MaoC_dehydrat_N)PF16073(SAT) | 4 | THR G 286THR G 252LEU G 156LEU G 267 | None | 1.05A | 4lvcB-2uv8G:undetectable | 4lvcB-2uv8G:12.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzz | N-METHYL-L-TRYPTOPHAN OXIDASE (Escherichiacoli) |
PF01266(DAO) | 4 | THR A 31THR A 329LEU A 208LEU A 207 | NoneNoneNoneFAD A1373 (-3.9A) | 1.10A | 4lvcB-2uzzA:undetectable | 4lvcB-2uzzA:20.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 73THR A 74THR A 219LEU A 407LEU A 410 | ADN A 500 (-3.6A)ADN A 500 (-4.5A)NAD A 550 ( 2.8A)NAD A 550 (-4.2A)ADN A 500 ( 4.8A) | 0.61A | 4lvcB-3ce6A:59.2 | 4lvcB-3ce6A:58.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cq0 | PUTATIVETRANSALDOLASEYGR043C (Saccharomycescerevisiae) |
PF00923(TAL_FSA) | 4 | THR A 45THR A 24LEU A 264LEU A 261 | GOL A 354 ( 4.4A)NoneNoneNone | 0.96A | 4lvcB-3cq0A:2.3 | 4lvcB-3cq0A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cqy | ANHYDRO-N-ACETYLMURAMIC ACID KINASE (Shewanellaoneidensis) |
PF03702(AnmK) | 4 | GLN A 288THR A 189LEU A 308LEU A 312 | None | 1.10A | 4lvcB-3cqyA:undetectable | 4lvcB-3cqyA:22.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 ALPHACHAIN (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF14710(Nitr_red_alph_N) | 4 | GLN A 229THR A1195THR A 608LEU A 550 | None | 1.04A | 4lvcB-3egwA:undetectable | 4lvcB-3egwA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 4 | GLN A 292THR A 291THR A 337LEU A 332 | None | 0.85A | 4lvcB-3eqnA:undetectable | 4lvcB-3eqnA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ew5 | MACRO DOMAIN OFNON-STRUCTURALPROTEIN 3 (Alphacoronavirus1) |
PF01661(Macro) | 4 | GLN A 190THR A 188LEU A 170LEU A 166 | None | 1.03A | 4lvcB-3ew5A:undetectable | 4lvcB-3ew5A:17.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156LEU A 343LEU A 346 | ADN A 438 (-3.8A)ADN A 438 (-4.6A)NAD A 439 ( 3.0A)NAD A 439 ( 4.0A)ADN A 438 ( 4.8A) | 0.58A | 4lvcB-3g1uA:55.7 | 4lvcB-3g1uA:60.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5w | MULTICOPPER OXIDASETYPE 1 (Nitrosomonaseuropaea) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | THR A 220THR A 247LEU A 235LEU A 184 | None | 1.10A | 4lvcB-3g5wA:undetectable | 4lvcB-3g5wA:21.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3glq | ADENOSYLHOMOCYSTEINASE (Burkholderiapseudomallei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 200LEU A 385LEU A 388 | RAB A 602 (-3.9A)RAB A 602 (-4.5A)NAD A 601 ( 2.9A)NAD A 601 ( 4.1A)RAB A 602 ( 4.7A) | 0.51A | 4lvcB-3glqA:61.1 | 4lvcB-3glqA:65.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 56THR A 57THR A 156LEU A 343LEU A 346 | ADN A 439 (-3.6A)ADN A 439 (-4.7A)NAD A 438 (-3.8A)NAD A 438 (-4.0A)ADN A 439 ( 4.7A) | 0.42A | 4lvcB-3h9uA:57.6 | 4lvcB-3h9uA:58.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hz6 | XYLULOKINASE (Chromobacteriumviolaceum) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | GLN A 215THR A 233THR A 7LEU A 450 | None | 1.05A | 4lvcB-3hz6A:undetectable | 4lvcB-3hz6A:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv7 | ALCOHOLDEHYDROGENASE IV (Corynebacteriumglutamicum) |
PF00465(Fe-ADH) | 4 | THR A 261THR A 246LEU A 341LEU A 344 | None | 0.90A | 4lvcB-3iv7A:3.0 | 4lvcB-3iv7A:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m19 | VARIABLE LYMPHOCYTERECEPTOR A DIVERSITYREGION (Petromyzonmarinus) |
PF13855(LRR_8) | 4 | THR A 36THR A 53LEU A 65LEU A 63 | None | 1.12A | 4lvcB-3m19A:undetectable | 4lvcB-3m19A:19.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 59THR A 60THR A 193LEU A 378LEU A 381 | K A 2 ( 3.3A)ADN A 500 (-4.6A)NAD A 550 ( 3.0A)NAD A 550 (-4.3A)ADN A 500 ( 4.8A) | 0.50A | 4lvcB-3n58A:62.6 | 4lvcB-3n58A:69.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n9x | PHOSPHOTRANSFERASE (Plasmodiumberghei) |
PF00069(Pkinase) | 4 | THR A 238THR A 133LEU A 162LEU A 116 | None | 1.06A | 4lvcB-3n9xA:undetectable | 4lvcB-3n9xA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nie | MAP2 KINASE (Plasmodiumfalciparum) |
PF00069(Pkinase) | 4 | THR A 243THR A 135LEU A 164LEU A 118 | None | 1.06A | 4lvcB-3nieA:undetectable | 4lvcB-3nieA:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o2x | COLLAGENASE 3 (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | GLN A1263THR A1149LEU A1239LEU A1254 | NoneNone3O2 A1801 (-4.5A)None | 0.99A | 4lvcB-3o2xA:undetectable | 4lvcB-3o2xA:15.85 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 66THR A 67THR A 206LEU A 395LEU A 398 | ADE A 506 (-3.8A)ADE A 506 (-4.5A)NAD A 501 (-2.8A)NAD A 501 (-4.2A)ADE A 506 ( 4.7A) | 0.33A | 4lvcB-3oneA:57.6 | 4lvcB-3oneA:62.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3opy | 6-PHOSPHOFRUCTO-1-KINASE GAMMA-SUBUNIT (Komagataellapastoris) |
no annotation | 4 | GLN I 279THR I 281LEU I 99LEU I 95 | None | 1.12A | 4lvcB-3opyI:2.2 | 4lvcB-3opyI:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sxp | ADP-L-GLYCERO-D-MANNOHEPTOSE-6-EPIMERASE (Helicobacterpylori) |
PF01370(Epimerase) | 4 | GLN A 117THR A 16LEU A 86LEU A 83 | None | 1.09A | 4lvcB-3sxpA:5.4 | 4lvcB-3sxpA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sxp | ADP-L-GLYCERO-D-MANNOHEPTOSE-6-EPIMERASE (Helicobacterpylori) |
PF01370(Epimerase) | 4 | GLN A 117THR A 114LEU A 86LEU A 83 | NoneNAD A2402 ( 4.9A)NoneNone | 0.96A | 4lvcB-3sxpA:5.4 | 4lvcB-3sxpA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t3o | METAL DEPENDENTHYDROLASE (Thermusthermophilus) |
PF07521(RMMBL)PF12706(Lactamase_B_2) | 4 | THR A 162THR A 26LEU A 395LEU A 200 | None | 1.12A | 4lvcB-3t3oA:undetectable | 4lvcB-3t3oA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ttl | POLYAMINE TRANSPORTPROTEIN (Pseudomonasaeruginosa) |
PF13416(SBP_bac_8) | 4 | GLN A 354THR A 357LEU A 192LEU A 187 | None | 0.90A | 4lvcB-3ttlA:undetectable | 4lvcB-3ttlA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9w | LEUKOTRIENE A-4HYDROLASE (Homo sapiens) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 4 | THR A1302THR A1421LEU A1389LEU A1390 | None | 0.99A | 4lvcB-3u9wA:undetectable | 4lvcB-3u9wA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v96 | STROMELYSIN-2 (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | GLN B 259THR B 144LEU B 234LEU B 250 | None | 0.99A | 4lvcB-3v96B:undetectable | 4lvcB-3v96B:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4arv | PHYTASE (Yersiniakristensenii) |
PF00328(His_Phos_2) | 4 | GLN A 290THR A 291LEU A 15LEU A 303 | None | 1.12A | 4lvcB-4arvA:undetectable | 4lvcB-4arvA:24.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4auo | INTERSTITIALCOLLAGENASE (Homo sapiens) |
PF00045(Hemopexin)PF00413(Peptidase_M10) | 4 | GLN A 238THR A 126LEU A 216LEU A 229 | None | 1.11A | 4lvcB-4auoA:undetectable | 4lvcB-4auoA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bc5 | XYLULOSE KINASE (Homo sapiens) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | GLN A 223THR A 163LEU A 241LEU A 234 | None | 0.99A | 4lvcB-4bc5A:undetectable | 4lvcB-4bc5A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bc5 | XYLULOSE KINASE (Homo sapiens) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | GLN A 223THR A 172LEU A 241LEU A 234 | None | 1.08A | 4lvcB-4bc5A:undetectable | 4lvcB-4bc5A:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ccs | CBIX (Paracoccuspantotrophus) |
PF01903(CbiX) | 4 | GLN A 113THR A 112LEU A 178LEU A 206 | None | 1.07A | 4lvcB-4ccsA:undetectable | 4lvcB-4ccsA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fek | PUTATIVE DIFLAVINFLAVOPROTEIN A 5 (Nostoc sp. PCC7120) |
no annotation | 4 | GLN A 10THR A 18LEU A 226LEU A 234 | None | 1.10A | 4lvcB-4fekA:undetectable | 4lvcB-4fekA:19.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fvl | COLLAGENASE 3 (Homo sapiens) |
PF00045(Hemopexin)PF00413(Peptidase_M10) | 4 | GLN A 263THR A 149LEU A 239LEU A 254 | None | 1.00A | 4lvcB-4fvlA:undetectable | 4lvcB-4fvlA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fvl | COLLAGENASE 3 (Homo sapiens) |
PF00045(Hemopexin)PF00413(Peptidase_M10) | 4 | GLN A 401THR A 394LEU A 373LEU A 375 | PGO A 522 (-2.9A)NoneNoneNone | 0.85A | 4lvcB-4fvlA:undetectable | 4lvcB-4fvlA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gaa | MGC78867 PROTEIN (Xenopus laevis) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 4 | THR A 299THR A 418LEU A 386LEU A 387 | None | 0.98A | 4lvcB-4gaaA:undetectable | 4lvcB-4gaaA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ha7 | 2,5-DIAMINO-6-RIBOSYLAMINO-4(3H)-PYRIMIDINONE 5'-PHOSPHATEREDUCTASE (Saccharomycescerevisiae) |
PF01872(RibD_C) | 4 | THR A 33THR A 202LEU A 10LEU A 14 | None | 1.03A | 4lvcB-4ha7A:undetectable | 4lvcB-4ha7A:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ifa | EXTRACELLULARPROTEIN CONTAINING ASCP DOMAIN (Bacillusanthracis) |
PF00188(CAP)PF14504(CAP_assoc_N) | 4 | GLN A 250THR A 338LEU A 278LEU A 282 | None | 1.06A | 4lvcB-4ifaA:undetectable | 4lvcB-4ifaA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6e | UDP-2,3-DIACYLGLUCOSAMINEPYROPHOSPHATASE LPXI (Caulobactervibrioides) |
PF06230(DUF1009) | 4 | GLN A 169THR A 187LEU A 134LEU A 252 | UDG A 301 (-3.8A)UDG A 301 (-3.8A)NoneNone | 1.00A | 4lvcB-4j6eA:undetectable | 4lvcB-4j6eA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n1a | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 4 | GLN A1309THR A1310THR A1305LEU A1291 | ATP A1402 ( 4.8A)ATP A1402 (-4.7A)NoneNone | 0.95A | 4lvcB-4n1aA:undetectable | 4lvcB-4n1aA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6d | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | THR A 154THR A 230LEU A 182LEU A 164 | None | 1.06A | 4lvcB-4n6dA:undetectable | 4lvcB-4n6dA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nh0 | CELLDIVISIONFTSK/SPOIIIE (Thermomonosporacurvata) |
PF01580(FtsK_SpoIIIE) | 4 | GLN A1309THR A1310THR A1305LEU A1291 | ATP A1404 ( 4.8A)ATP A1404 (-4.4A)NoneNone | 1.00A | 4lvcB-4nh0A:2.4 | 4lvcB-4nh0A:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nu7 | RIBULOSE-PHOSPHATE3-EPIMERASE (Toxoplasmagondii) |
PF00834(Ribul_P_3_epim) | 4 | THR A 169THR A 128LEU A 122LEU A 145 | None | 1.04A | 4lvcB-4nu7A:undetectable | 4lvcB-4nu7A:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o38 | CYCLIN-G-ASSOCIATEDKINASE (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 184THR A 147LEU A 130LEU A 181 | None | 1.12A | 4lvcB-4o38A:undetectable | 4lvcB-4o38A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p8s | RETICULON-4RECEPTOR-LIKE 2 (Rattusnorvegicus) |
PF13855(LRR_8) | 4 | THR A 79THR A 126LEU A 113LEU A 89 | None | 1.04A | 4lvcB-4p8sA:undetectable | 4lvcB-4p8sA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phc | HISTIDINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF03129(HGTP_anticodon)PF13393(tRNA-synt_His) | 4 | GLN A 410THR A 409LEU A 427LEU A 431 | None | 1.07A | 4lvcB-4phcA:undetectable | 4lvcB-4phcA:24.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pw0 | ALPHA/BETA HYDROLASEFOLD PROTEIN (Chitinophagapinensis) |
PF00561(Abhydrolase_1) | 4 | GLN A 40THR A 45LEU A 178LEU A 181 | None | 1.10A | 4lvcB-4pw0A:undetectable | 4lvcB-4pw0A:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r6l | BACTERIOPHYTOCHROME(LIGHT-REGULATEDSIGNAL TRANSDUCTIONHISTIDINE KINASE),PHYB1 (Rhodopseudomonaspalustris) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | THR A 72THR A 52LEU A 31LEU A 118 | None | 1.06A | 4lvcB-4r6lA:undetectable | 4lvcB-4r6lA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rl5 | EXOCYST COMPLEXCOMPONENT EXO70A1 (Arabidopsisthaliana) |
PF03081(Exo70) | 4 | GLN A 424THR A 420LEU A 332LEU A 336 | None | 1.01A | 4lvcB-4rl5A:undetectable | 4lvcB-4rl5A:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s38 | 4-HYDROXY-3-METHYLBUT-2-EN-1-YLDIPHOSPHATE SYNTHASE (Thermusthermophilus) |
PF04551(GcpE) | 4 | GLN A 223THR A 222LEU A 194LEU A 190 | 1PE A 908 (-3.8A)NoneNone1PE A 908 (-4.3A) | 1.03A | 4lvcB-4s38A:undetectable | 4lvcB-4s38A:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x0q | DNA POLYMERASE THETA (Homo sapiens) |
PF00476(DNA_pol_A) | 4 | GLN A2441THR A2442LEU A2064LEU A2069 | None | 1.00A | 4lvcB-4x0qA:undetectable | 4lvcB-4x0qA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x82 | ZINC TRANSPORTERZIP4 (Pteropus alecto) |
no annotation | 4 | GLN B 140THR B 143LEU B 176LEU B 179 | None | 1.01A | 4lvcB-4x82B:undetectable | 4lvcB-4x82B:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzb | CELA (Geobacillus sp.70PC53) |
PF00150(Cellulase) | 4 | GLN A 42THR A 51LEU A 292LEU A 277 | None | 1.10A | 4lvcB-4xzbA:undetectable | 4lvcB-4xzbA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zgs | PUTATIVE D-LACTATEDEHYDROGENASE (Chlamydomonasreinhardtii) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | THR A 245THR A 236LEU A 228LEU A 225 | NAD A1000 (-4.0A)NoneNoneNone | 1.07A | 4lvcB-4zgsA:5.0 | 4lvcB-4zgsA:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5t | EUKARYOTICTRANSLATIONINITIATION FACTOR 3SUBUNIT A (Oryctolaguscuniculus) |
PF01399(PCI) | 4 | GLN A 79THR A 42LEU A 55LEU A 52 | None | 1.02A | 4lvcB-5a5tA:undetectable | 4lvcB-5a5tA:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2v | HYDRAZINE SYNTHASEALPHA SUBUNIT (CandidatusKueneniastuttgartiensis) |
no annotation | 4 | GLN A 315THR A 319LEU A 356LEU A 340 | None | 1.02A | 4lvcB-5c2vA:undetectable | 4lvcB-5c2vA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ehk | LANTIBIOTICDEHYDRATASE (Microbisporacorallina) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 4 | THR A 484THR A 686LEU A 394LEU A 397 | None | 1.10A | 4lvcB-5ehkA:undetectable | 4lvcB-5ehkA:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fbu | PHOSPHOENOLPYRUVATESYNTHASE (Listeriamonocytogenes) |
PF00391(PEP-utilizers)PF01326(PPDK_N) | 4 | GLN A 549THR A 550THR A 568LEU A 606 | None | 0.98A | 4lvcB-5fbuA:undetectable | 4lvcB-5fbuA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g06 | EXOSOME COMPLEXCOMPONENT RRP4 (Saccharomycescerevisiae) |
PF14382(ECR1_N)PF15985(KH_6) | 4 | GLN H 201THR H 214LEU H 194LEU H 168 | None | 1.00A | 4lvcB-5g06H:undetectable | 4lvcB-5g06H:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m45 | ACETONE CARBOXYLASEBETA SUBUNIT (Xanthobacterautotrophicus) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 4 | GLN B 40THR B 21THR B 695LEU B 412 | NoneAMP B 801 (-4.0A)AMP B 801 (-3.8A)None | 0.87A | 4lvcB-5m45B:undetectable | 4lvcB-5m45B:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nji | PHTHIOCEROL/PHENOLPHTHIOCEROL SYNTHESISPOLYKETIDE SYNTHASETYPE I PPSC (Mycobacteriumtuberculosis) |
PF14765(PS-DH) | 4 | GLN A1133THR A1142LEU A1070LEU A1096 | None | 0.82A | 4lvcB-5njiA:undetectable | 4lvcB-5njiA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0l | RETICULON-4 RECEPTOR (Mus musculus) |
no annotation | 4 | THR A 125THR A 173LEU A 161LEU A 137 | None | 1.10A | 4lvcB-5o0lA:undetectable | 4lvcB-5o0lA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ocm | NAD_GLY3P_DH,NAD-DEPENDENTGLYCEROL-3-PHOSPHATEDEHYDROGENASE (Streptosporangiumroseum) |
no annotation | 4 | THR A 93THR A 7LEU A 80LEU A 77 | NAP A 301 ( 4.3A)NoneNoneNone | 0.82A | 4lvcB-5ocmA:4.9 | 4lvcB-5ocmA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojr | - (-) |
no annotation | 4 | GLN A 51THR A 54THR A 81LEU A 335 | None | 1.04A | 4lvcB-5ojrA:undetectable | 4lvcB-5ojrA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6s | UDP-GLYCOSYLTRANSFERASE 74F2 (Arabidopsisthaliana) |
PF00201(UDPGT) | 4 | GLN A 24THR A 20LEU A 331LEU A 328 | NoneUDP A 503 ( 4.3A)NoneNone | 0.92A | 4lvcB-5u6sA:4.9 | 4lvcB-5u6sA:20.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5utu | ADENOSYLHOMOCYSTEINASE (Cryptosporidiumparvum) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 58THR A 212LEU A 401LEU A 404 | SAH A 502 (-4.2A)NAD A 501 ( 4.1A)NAD A 501 (-4.1A)SAH A 502 ( 4.7A) | 0.45A | 4lvcB-5utuA:54.7 | 4lvcB-5utuA:51.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v76 | MICROCOMPARTMENTSPROTEIN (Haliangiumochraceum) |
no annotation | 4 | GLN A 21THR A 169LEU A 9LEU A 12 | None | 0.95A | 4lvcB-5v76A:undetectable | 4lvcB-5v76A:19.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5v96 | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE (Naegleriafowleri) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 64THR A 198LEU A 386LEU A 389 | ADN A 502 (-4.4A)NAD A 501 ( 2.9A)NAD A 501 (-3.9A)ADN A 502 ( 4.7A) | 0.18A | 4lvcB-5v96A:60.6 | 4lvcB-5v96A:62.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve8 | KAP123 (Kluyveromyceslactis) |
no annotation | 4 | GLN A 395THR A 392LEU A 366LEU A 362 | None | 0.91A | 4lvcB-5ve8A:undetectable | 4lvcB-5ve8A:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xua | METHYL-ACCEPTINGCHEMOTAXIS SENSORYTRANSDUCER (Comamonastestosteroni) |
no annotation | 4 | THR A 82THR A 108LEU A 176LEU A 173 | None | 1.08A | 4lvcB-5xuaA:undetectable | 4lvcB-5xuaA:10.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9y | THIAZOLE SYNTHASE (Mycobacteriumtuberculosis) |
no annotation | 4 | GLN A 32THR A 21LEU A 61LEU A 64 | None | 1.01A | 4lvcB-5z9yA:2.4 | 4lvcB-5z9yA:11.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | GLN A 62THR A 63THR A 162LEU A 349LEU A 352 | ADN A 501 (-3.8A)ADN A 501 (-4.5A)NAD A 500 ( 2.9A)NAD A 500 ( 4.3A)ADN A 501 ( 4.8A) | 0.59A | 4lvcB-6aphA:58.3 | 4lvcB-6aphA:60.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehs | HYDROGENASE-2 LARGECHAIN (Escherichiacoli) |
no annotation | 4 | GLN L 406THR L 409THR L 262LEU L 413 | None | 1.06A | 4lvcB-6ehsL:undetectable | 4lvcB-6ehsL:10.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ewj | PUTATIVE CAPSULARPOLYSACCHARIDEBIOSYNTHESIS PROTEIN (Streptococcuspneumoniae) |
no annotation | 4 | GLN A 271THR A 203THR A 52LEU A 175 | None | 1.03A | 4lvcB-6ewjA:undetectable | 4lvcB-6ewjA:10.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 5 | GLN B 65THR B 66THR B 165LEU B 373LEU B 376 | K B 504 ( 3.0A)ADN B 502 (-4.6A)NAD B 501 ( 2.8A)NAD B 501 ( 3.9A)ADN B 502 ( 4.8A) | 0.25A | 4lvcB-6f3mB:53.4 | 4lvcB-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 5 | GLN A 60THR A 61THR A 160LEU A 347LEU A 350 | NA A 503 ( 3.2A)ADN A 501 (-4.6A)NAD A 502 ( 2.8A)NAD A 502 (-3.9A)ADN A 501 ( 4.7A) | 0.19A | 4lvcB-6gbnA:58.3 | 4lvcB-6gbnA:undetectable |