SIMILAR PATTERNS OF AMINO ACIDS FOR 4LTW_A_STRA301_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1awc | PROTEIN (GA BINDINGPROTEIN ALPHA)PROTEIN (GA BINDINGPROTEIN BETA 1) (Mus musculus) |
PF00178(Ets)PF12796(Ank_2)PF13637(Ank_4) | 4 | TRP B 110THR A 331VAL A 418PHE B 136 | None | 0.96A | 4ltwA-1awcB:undetectable | 4ltwA-1awcB:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ciy | CRYIA(A) (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 4 | ALA A 606PHE A 570THR A 538PHE A 583 | None | 1.03A | 4ltwA-1ciyA:undetectable | 4ltwA-1ciyA:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dly | HEMOGLOBIN (Chlamydomonasmoewusii) |
PF01152(Bac_globin) | 4 | ALA A 15THR A 111VAL A 115PHE A 80 | NoneHEM A 144 ( 4.1A)NoneHEM A 144 (-4.4A) | 0.77A | 4ltwA-1dlyA:undetectable | 4ltwA-1dlyA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dml | DNA POLYMERASEPROCESSIVITY FACTOR (Humanalphaherpesvirus1) |
PF02282(Herpes_UL42) | 4 | ALA A 303THR A 192VAL A 212PHE A 202 | None | 1.04A | 4ltwA-1dmlA:undetectable | 4ltwA-1dmlA:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fui | L-FUCOSE ISOMERASE (Escherichiacoli) |
PF02952(Fucose_iso_C)PF07881(Fucose_iso_N1)PF07882(Fucose_iso_N2) | 4 | MET A 172THR A 532VAL A 536PHE A 540 | None | 0.87A | 4ltwA-1fuiA:undetectable | 4ltwA-1fuiA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1omx | ALPHA-1,4-N-ACETYLHEXOSAMINYLTRANSFERASEEXTL2 (Mus musculus) |
PF09258(Glyco_transf_64) | 4 | MET A 249ALA A 248VAL A 99PHE A 139 | None | 0.94A | 4ltwA-1omxA:undetectable | 4ltwA-1omxA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pss | PHOTOSYNTHETICREACTION CENTER (Rhodobactersphaeroides) |
PF00124(Photo_RC) | 4 | ALA M 273PHE M 150THR M 133PHE L 215 | BPH M 5 (-4.2A)BPH M 5 (-3.7A)BPH M 5 ( 4.2A)None | 1.00A | 4ltwA-1pssM:undetectable | 4ltwA-1pssM:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q3b | ENDONUCLEASE VIII (Escherichiacoli) |
PF01149(Fapy_DNA_glyco)PF06827(zf-FPG_IleRS)PF06831(H2TH) | 4 | ALA A 28THR A 56VAL A 44PHE A 58 | None | 0.96A | 4ltwA-1q3bA:undetectable | 4ltwA-1q3bA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgi | PROTEIN(CHITOSANASE) (Bacilluscirculans) |
PF01374(Glyco_hydro_46) | 4 | MET A 109THR A 143VAL A 147PHE A 64 | None | 0.99A | 4ltwA-1qgiA:undetectable | 4ltwA-1qgiA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qx6 | NPQTN SPECIFICSORTASE B (Staphylococcusaureus) |
PF04203(Sortase) | 4 | PHE A 195THR A 199VAL A 237PHE A 170 | None | 0.93A | 4ltwA-1qx6A:undetectable | 4ltwA-1qx6A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rf5 | 5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATESYNTHASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 4 | ALA A 180MET A 132THR A 196PHE A 29 | None | 1.04A | 4ltwA-1rf5A:undetectable | 4ltwA-1rf5A:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sp8 | 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (Zea mays) |
PF00903(Glyoxalase) | 4 | ALA A 160THR A 46VAL A 270PHE A 240 | None | 1.01A | 4ltwA-1sp8A:undetectable | 4ltwA-1sp8A:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7g | PROBABLE AMMONIUMTRANSPORTER (Escherichiacoli) |
PF00909(Ammonium_transp) | 4 | TRP A 135ALA A 108VAL A 314PHE A 315 | NoneNoneBOG A 400 ( 4.0A)None | 1.03A | 4ltwA-1u7gA:undetectable | 4ltwA-1u7gA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uvx | GLOBIN LI637 (Chlamydomonasmoewusii) |
PF01152(Bac_globin) | 4 | ALA A 15THR A 111VAL A 115PHE A 80 | XE A1127 ( 3.9A)HEM A1122 (-4.3A)HEM A1122 (-4.9A)HEM A1122 (-3.7A) | 0.74A | 4ltwA-1uvxA:undetectable | 4ltwA-1uvxA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vkh | PUTATIVE SERINEHYDROLASE (Saccharomycescerevisiae) |
PF07859(Abhydrolase_3) | 4 | ALA A 122MET A 137PHE A 115PHE A 174 | None | 1.03A | 4ltwA-1vkhA:undetectable | 4ltwA-1vkhA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a1r | POLY(A)-SPECIFICRIBONUCLEASE PARN (Homo sapiens) |
PF01424(R3H)PF04857(CAF1) | 4 | MET A 328ALA A 329VAL A 360PHE A 74 | None | 1.00A | 4ltwA-2a1rA:undetectable | 4ltwA-2a1rA:22.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | MET A 745MET A 787PHE A 876VAL A 889PHE A 891 | BHM A 1 (-3.9A)BHM A 1 (-3.6A)NoneNoneNone | 0.86A | 4ltwA-2ax9A:36.1 | 4ltwA-2ax9A:60.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | TRP A 741MET A 787PHE A 876VAL A 889PHE A 891 | NoneBHM A 1 (-3.6A)NoneNoneNone | 1.25A | 4ltwA-2ax9A:36.1 | 4ltwA-2ax9A:60.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e0p | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF12891(Glyco_hydro_44) | 4 | ALA A 373THR A 459VAL A 10PHE A 461 | None | 0.95A | 4ltwA-2e0pA:undetectable | 4ltwA-2e0pA:17.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ebd | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 3 (Aquifexaeolicus) |
PF08541(ACP_syn_III_C)PF08545(ACP_syn_III) | 4 | MET A 293ALA A 304MET A 179VAL A 133 | None | 1.03A | 4ltwA-2ebdA:undetectable | 4ltwA-2ebdA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fk5 | FUCULOSE-1-PHOSPHATEALDOLASE (Thermusthermophilus) |
PF00596(Aldolase_II) | 4 | ALA A 153MET A 173PHE A 29THR A 40 | None | 0.99A | 4ltwA-2fk5A:undetectable | 4ltwA-2fk5A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fk5 | FUCULOSE-1-PHOSPHATEALDOLASE (Thermusthermophilus) |
PF00596(Aldolase_II) | 4 | ALA A 153PHE A 29THR A 40VAL A 44 | None | 0.96A | 4ltwA-2fk5A:undetectable | 4ltwA-2fk5A:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h0a | TRANSCRIPTIONALREGULATOR (Thermusthermophilus) |
PF13377(Peripla_BP_3) | 4 | ALA A 285PHE A 77VAL A 197PHE A 198 | None | 0.89A | 4ltwA-2h0aA:undetectable | 4ltwA-2h0aA:22.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q3y | ANCESTRAL CORTICIODRECEPTOR (unidentified) |
PF00104(Hormone_recep) | 8 | TRP A 69MET A 73ALA A 74MET A 115PHE A 204THR A 208VAL A 217PHE A 219 | None1CA A 247 (-3.6A)1CA A 247 ( 4.4A)1CA A 247 ( 3.7A)1CA A 247 (-4.7A)1CA A 247 (-3.4A)None1CA A 247 (-4.5A) | 0.34A | 4ltwA-2q3yA:40.6 | 4ltwA-2q3yA:90.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qru | UNCHARACTERIZEDPROTEIN (Enterococcusfaecalis) |
PF07859(Abhydrolase_3) | 4 | PHE A 212THR A 214VAL A 242PHE A 249 | None | 1.00A | 4ltwA-2qruA:undetectable | 4ltwA-2qruA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r1h | HEMOGLOBIN SUBUNITALPHA-4HEMOGLOBIN SUBUNITBETA-4 (Oncorhynchusmykiss) |
PF00042(Globin) | 4 | TRP A 14MET A 64VAL B 112PHE A 118 | None | 1.03A | 4ltwA-2r1hA:undetectable | 4ltwA-2r1hA:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vmh | FIBRONECTIN TYPE IIIDOMAIN PROTEIN (Clostridiumperfringens) |
PF08305(NPCBM) | 4 | ALA A 918THR A 975VAL A1016PHE A 973 | None | 1.03A | 4ltwA-2vmhA:undetectable | 4ltwA-2vmhA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wgh | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASELARGE SUBUNIT (Homo sapiens) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC) | 4 | TRP A 581ALA A 700THR A 470VAL A 474 | None | 1.00A | 4ltwA-2wghA:undetectable | 4ltwA-2wghA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4l | FERRIC-SIDEROPHORERECEPTOR PROTEIN (Streptomycescoelicolor) |
PF01497(Peripla_BP_2) | 4 | ALA A 293THR A 141VAL A 171PHE A 143 | None | 1.02A | 4ltwA-2x4lA:undetectable | 4ltwA-2x4lA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3au0 | CLUMPING FACTOR B (Staphylococcusaureus) |
PF10425(SdrG_C_C) | 4 | ALA A 334THR A 393VAL A 486PHE A 395 | None | 1.04A | 4ltwA-3au0A:undetectable | 4ltwA-3au0A:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b85 | PHOSPHATESTARVATION-INDUCIBLEPROTEIN (Corynebacteriumglutamicum) |
PF02562(PhoH) | 4 | ALA A 201MET A 205PHE A 237VAL A 137 | SO4 A 409 ( 4.1A)NoneNoneNone | 1.04A | 4ltwA-3b85A:undetectable | 4ltwA-3b85A:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cf4 | ACETYL-COADECARBOXYLASE/SYNTHASE EPSILON SUBUNIT (Methanosarcinabarkeri) |
PF02552(CO_dh) | 4 | ALA G 45PHE G 151THR G 4VAL G 2 | ACY A 819 ( 4.3A)NoneNoneNone | 0.95A | 4ltwA-3cf4G:undetectable | 4ltwA-3cf4G:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cny | INOSITOL CATABOLISMPROTEIN IOLE (Lactobacillusplantarum) |
PF01261(AP_endonuc_2) | 4 | MET A 285ALA A 286PHE A 216THR A 190 | None | 0.90A | 4ltwA-3cnyA:undetectable | 4ltwA-3cnyA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d45 | POLY(A)-SPECIFICRIBONUCLEASE PARN (Mus musculus) |
PF01424(R3H)PF04857(CAF1)PF08675(RNA_bind) | 4 | MET A 321ALA A 322VAL A 353PHE A 74 | None | 0.93A | 4ltwA-3d45A:undetectable | 4ltwA-3d45A:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3emq | ENDO-1,4-BETA-XYLANASE (Paenibacillusbarcinonensis) |
PF00331(Glyco_hydro_10) | 4 | MET A 263ALA A 264PHE A 313THR A 298 | None | 0.99A | 4ltwA-3emqA:undetectable | 4ltwA-3emqA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fa3 | 2,3-DIMETHYLMALATELYASE (Aspergillusniger) |
PF13714(PEP_mutase) | 4 | MET A 251ALA A 249PHE A 241THR A 46 | NoneNoneNoneOAF A 501 (-3.3A) | 0.89A | 4ltwA-3fa3A:undetectable | 4ltwA-3fa3A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3flj | UNCHARACTERIZEDPROTEIN CONSERVED INBACTERIA WITH ACYSTATIN-LIKE FOLD (Ruegeriapomeroyi) |
PF12680(SnoaL_2) | 4 | ALA A 120PHE A 56VAL A 103PHE A 30 | None | 1.00A | 4ltwA-3fljA:undetectable | 4ltwA-3fljA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fwr | YQZB PROTEIN (Bacillussubtilis) |
PF00571(CBS) | 4 | ALA A 167THR A 110VAL A 123PHE A 112 | NoneADP A 221 ( 3.9A)NoneNone | 0.97A | 4ltwA-3fwrA:undetectable | 4ltwA-3fwrA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hmj | FATTY ACID SYNTHASESUBUNIT ALPHA (Saccharomycescerevisiae) |
PF00109(ketoacyl-synt)PF01648(ACPS)PF02801(Ketoacyl-synt_C) | 4 | ALA A 867PHE A 903VAL A 671PHE A 673 | None | 0.95A | 4ltwA-3hmjA:undetectable | 4ltwA-3hmjA:8.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kba | PROGESTERONERECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | MET A 759MET A 801THR A 894VAL A 903PHE A 905 | WOW A 1 (-3.7A)WOW A 1 (-4.2A)WOW A 1 (-3.9A)NoneWOW A 1 (-4.6A) | 0.59A | 4ltwA-3kbaA:36.7 | 4ltwA-3kbaA:66.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kba | PROGESTERONERECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | TRP A 755MET A 801THR A 894VAL A 903PHE A 905 | NoneWOW A 1 (-4.2A)WOW A 1 (-3.9A)NoneWOW A 1 (-4.6A) | 1.01A | 4ltwA-3kbaA:36.7 | 4ltwA-3kbaA:66.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l7z | PROBABLE EXOSOMECOMPLEX EXONUCLEASE2 (Sulfolobussolfataricus) |
PF01138(RNase_PH)PF03725(RNase_PH_C) | 4 | ALA A 199MET A 217THR A 61VAL A 146 | None | 0.96A | 4ltwA-3l7zA:undetectable | 4ltwA-3l7zA:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pow | CALRETICULIN (Homo sapiens) |
PF00262(Calreticulin) | 4 | ALA A 76MET A 122VAL A 93PHE A 95 | None | 1.04A | 4ltwA-3powA:undetectable | 4ltwA-3powA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rg0 | CALRETICULIN (Mus musculus) |
PF00262(Calreticulin) | 4 | ALA A 76MET A 122VAL A 93PHE A 95 | None | 1.00A | 4ltwA-3rg0A:undetectable | 4ltwA-3rg0A:20.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ry9 | ANCESTRALGLUCOCORTICOIDRECEPTOR 1 (syntheticconstruct) |
PF00104(Hormone_recep) | 8 | TRP A 69MET A 73ALA A 74MET A 115PHE A 204THR A 208VAL A 217PHE A 219 | None1CA A 249 (-3.9A)1CA A 249 ( 4.7A)1CA A 249 (-3.6A)1CA A 249 (-4.8A)1CA A 249 (-3.2A)1CA A 249 (-4.9A)1CA A 249 (-4.3A) | 0.51A | 4ltwA-3ry9A:38.4 | 4ltwA-3ry9A:81.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a0h | ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE (Arabidopsisthaliana) |
PF00202(Aminotran_3)PF13500(AAA_26) | 4 | MET A 441ALA A 442PHE A 614PHE A 642 | None | 1.01A | 4ltwA-4a0hA:undetectable | 4ltwA-4a0hA:14.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4anf | ORNITHINECARBAMOYLTRANSFERASE, CATABOLIC (Mycoplasmapenetrans) |
PF00185(OTCace)PF02729(OTCace_N) | 4 | ALA A 226PHE A 162THR A 174PHE A 145 | None | 1.04A | 4ltwA-4anfA:undetectable | 4ltwA-4anfA:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c1r | MANNOSYL-6-PHOSPHATASE (Bacteroidesthetaiotaomicron) |
PF03372(Exo_endo_phos) | 4 | MET A 58ALA A 56MET A 80PHE A 237 | None | 0.99A | 4ltwA-4c1rA:undetectable | 4ltwA-4c1rA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cqm | CARBONYL REDUCTASEFAMILY MEMBER 4 (Homo sapiens) |
PF13561(adh_short_C2) | 4 | ALA B 19THR B 114VAL B 63PHE B 67 | None | 1.00A | 4ltwA-4cqmB:undetectable | 4ltwA-4cqmB:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e5v | PUTATIVE THUA-LIKEPROTEIN (Parabacteroidesmerdae) |
PF06283(ThuA) | 4 | PHE A 265THR A 245VAL A 113PHE A 243 | None | 0.96A | 4ltwA-4e5vA:undetectable | 4ltwA-4e5vA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4elj | RETINOBLASTOMA-ASSOCIATED PROTEIN (Homo sapiens) |
PF01857(RB_B)PF01858(RB_A)PF11934(DUF3452) | 4 | MET A 148ALA A 147THR A 77VAL A 81 | None | 1.02A | 4ltwA-4eljA:undetectable | 4ltwA-4eljA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gfj | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 4 | ALA A 113THR A 333VAL A 337PHE A 319 | None | 0.97A | 4ltwA-4gfjA:undetectable | 4ltwA-4gfjA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j7h | EVAA 2,3-DEHYDRATASE (Amycolatopsisorientalis) |
PF03559(Hexose_dehydrat) | 4 | MET A 229ALA A 226THR A 443VAL A 449 | None | 0.97A | 4ltwA-4j7hA:undetectable | 4ltwA-4j7hA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7k | CATION EFFLUX SYSTEMPROTEIN CUSC (Escherichiacoli) |
PF02321(OEP) | 4 | ALA A 129THR A 64VAL A 144PHE A 119 | None | 1.00A | 4ltwA-4k7kA:undetectable | 4ltwA-4k7kA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k90 | EXTRACELLULARMETALLOPROTEINASEMEP (Aspergillusfumigatus) |
PF02128(Peptidase_M36) | 4 | MET A 465ALA A 466PHE A 395THR A 397 | None | 1.00A | 4ltwA-4k90A:undetectable | 4ltwA-4k90A:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kbf | HEAT RESISTANT RNADEPENDENT ATPASE (Thermusthermophilus) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ALA A 153MET A 156THR A 172VAL A 145 | None | 0.90A | 4ltwA-4kbfA:undetectable | 4ltwA-4kbfA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kva | SEPTIN (Schistosomamansoni) |
PF00735(Septin) | 4 | MET A 169ALA A 168THR A 157PHE A 196 | None | 0.65A | 4ltwA-4kvaA:undetectable | 4ltwA-4kvaA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l3w | LIPASE (Rhizopusmicrosporus) |
PF01764(Lipase_3) | 4 | ALA A 99THR A 53VAL A 59PHE A 93 | None | 0.80A | 4ltwA-4l3wA:undetectable | 4ltwA-4l3wA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mt1 | DRUG EFFLUX PROTEIN (Neisseriagonorrhoeae) |
PF00873(ACR_tran) | 4 | ALA A 461PHE A 935THR A1013VAL A 942 | None | 1.02A | 4ltwA-4mt1A:undetectable | 4ltwA-4mt1A:13.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 4 | TRP A 320PHE A 450VAL A 460PHE A 462 | None | 0.60A | 4ltwA-4n1yA:29.6 | 4ltwA-4n1yA:31.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nme | PROLINEDEHYDROGENASE ANDDELTA-1-PYRROLINE-5-CARBOXYLATEDEHYDROGENASE (Geobactersulfurreducens) |
PF00171(Aldedh)PF01619(Pro_dh) | 4 | MET A 816ALA A 817MET A 873THR A 948 | None | 0.92A | 4ltwA-4nmeA:undetectable | 4ltwA-4nmeA:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqr | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 4 | ALA A 271THR A 129VAL A 153PHE A 149 | None | 0.81A | 4ltwA-4oqrA:2.4 | 4ltwA-4oqrA:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqs | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 4 | ALA A 271THR A 129VAL A 153PHE A 149 | None | 0.80A | 4ltwA-4oqsA:3.2 | 4ltwA-4oqsA:22.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p6w | GLUCOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | TRP A 600ALA A 605MET A 646THR A 739PHE A 749 | NoneMOF A 801 ( 4.8A)MOF A 801 (-4.4A)MOF A 801 (-3.9A)MOF A 801 (-4.4A) | 0.75A | 4ltwA-4p6wA:36.6 | 4ltwA-4p6wA:62.45 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p6w | GLUCOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | TRP A 600MET A 604ALA A 605MET A 646PHE A 749 | NoneNoneMOF A 801 ( 4.8A)MOF A 801 (-4.4A)MOF A 801 (-4.4A) | 0.87A | 4ltwA-4p6wA:36.6 | 4ltwA-4p6wA:62.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4twr | NAD BINDINGSITE:NAD-DEPENDENTEPIMERASE/DEHYDRATASE:UDP-GLUCOSE4-EPIMERASE (Brucellaabortus) |
PF01370(Epimerase) | 4 | ALA A 298THR A 19VAL A 8PHE A 75 | None | 1.01A | 4ltwA-4twrA:undetectable | 4ltwA-4twrA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u33 | ALPHA-1,4-GLUCAN:MALTOSE-1-PHOSPHATEMALTOSYLTRANSFERASE (Mycobacteriumtuberculosis) |
PF00128(Alpha-amylase)PF11896(DUF3416) | 4 | MET A 269ALA A 267MET A 339THR A 242 | None | 0.97A | 4ltwA-4u33A:undetectable | 4ltwA-4u33A:15.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | TRP A 806MET A 852PHE A 941THR A 945VAL A 954PHE A 956 | NoneCV7 A1987 ( 3.7A)CV7 A1987 (-4.6A)CV7 A1987 (-3.1A)NoneCV7 A1987 ( 4.7A) | 0.48A | 4ltwA-4udbA:36.1 | 4ltwA-4udbA:65.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v2i | ESTERASE/LIPASE (Thalassospirasp. GB04J01) |
PF07859(Abhydrolase_3) | 4 | ALA A 107THR A 135VAL A 167PHE A 83 | None | 1.02A | 4ltwA-4v2iA:undetectable | 4ltwA-4v2iA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xuv | GLYCOSIDE HYDROLASEFAMILY 105 PROTEIN (Thielaviaterrestris) |
PF07470(Glyco_hydro_88) | 4 | ALA A 181PHE A 252THR A 256PHE A 200 | None | 1.00A | 4ltwA-4xuvA:undetectable | 4ltwA-4xuvA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywe | PUTATIVE ALDEHYDEDEHYDROGENASE (Burkholderiacenocepacia) |
PF00171(Aldedh) | 4 | ALA A 178THR A 230VAL A 234PHE A 224 | CA A 503 ( 4.5A)NoneNoneNone | 0.96A | 4ltwA-4yweA:undetectable | 4ltwA-4yweA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4j | FORMATE--TETRAHYDROFOLATE LIGASE (Tepidanaerobacteracetatoxydans) |
PF01268(FTHFS) | 4 | MET A 205ALA A 206PHE A 312THR A 299 | None | 1.03A | 4ltwA-5a4jA:undetectable | 4ltwA-5a4jA:18.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5g | FORMATE--TETRAHYDROFOLATE LIGASE (Tepidanaerobacteracetatoxydans) |
PF01268(FTHFS) | 4 | MET A 204ALA A 205PHE A 311THR A 298 | None | 0.97A | 4ltwA-5a5gA:undetectable | 4ltwA-5a5gA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bn7 | MALTODEXTRINGLUCOSIDASE (Escherichiacoli) |
PF00128(Alpha-amylase) | 4 | ALA A 405THR A 472VAL A 555PHE A 544 | None | 0.92A | 4ltwA-5bn7A:undetectable | 4ltwA-5bn7A:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bs5 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 4 | ALA A 495MET A 447THR A 511PHE A 343 | None | 0.99A | 4ltwA-5bs5A:undetectable | 4ltwA-5bs5A:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 4 | PHE A 627THR A 625VAL A 676PHE A 611 | None | 0.99A | 4ltwA-5cjuA:undetectable | 4ltwA-5cjuA:12.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1p | PTMO8 (Streptomycesplatensis) |
PF13561(adh_short_C2) | 4 | ALA A 78MET A 74THR A 22VAL A 226 | None | 1.04A | 4ltwA-5f1pA:undetectable | 4ltwA-5f1pA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fji | BETA-GLUCOSIDASE (Aspergillusfumigatus) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | MET A 448ALA A 449VAL A 74PHE A 100 | NoneNoneNoneEDO A1873 ( 4.0A) | 0.86A | 4ltwA-5fjiA:undetectable | 4ltwA-5fjiA:17.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fjj | BETA-GLUCOSIDASE (Aspergillusoryzae) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | MET A 448ALA A 449VAL A 75PHE A 100 | None | 0.98A | 4ltwA-5fjjA:undetectable | 4ltwA-5fjjA:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gxf | ACRYLYL-COAREDUCTASE ACUI (Ruegeriapomeroyi) |
PF00107(ADH_zinc_N) | 4 | MET A 293PHE A 132THR A 89VAL A 113 | None | 1.02A | 4ltwA-5gxfA:undetectable | 4ltwA-5gxfA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hm5 | TOPOISOMERASE V (Methanopyruskandleri) |
PF13412(HTH_24)PF14520(HHH_5) | 4 | ALA A 113THR A 333VAL A 337PHE A 319 | None | 1.01A | 4ltwA-5hm5A:undetectable | 4ltwA-5hm5A:14.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j78 | ACETALDEHYDEDEHYDROGENASE(ACETYLATING) (Parageobacillusthermoglucosidasius) |
PF00171(Aldedh) | 4 | MET A 180ALA A 177THR A 440VAL A 455 | None | 0.99A | 4ltwA-5j78A:undetectable | 4ltwA-5j78A:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jd4 | LAE6 (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | MET A 166ALA A 165PHE A 289THR A 102 | None | 1.00A | 4ltwA-5jd4A:undetectable | 4ltwA-5jd4A:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mac | RIBULOSE-1,5-BISPHOSPHATECARBOXYLASE-OXYGENASE TYPE III (Methanococcoidesburtonii) |
PF00016(RuBisCO_large)PF02788(RuBisCO_large_N) | 4 | MET A 209ALA A 211VAL A 283PHE A 261 | None | 0.98A | 4ltwA-5macA:undetectable | 4ltwA-5macA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mlh | - (-) |
no annotation | 4 | ALA A 382PHE A 207VAL A 347PHE A 343 | NoneNoneXOG A 402 (-3.6A)NAP A 404 ( 4.8A) | 1.01A | 4ltwA-5mlhA:undetectable | 4ltwA-5mlhA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mwp | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
no annotation | 5 | TRP A 806PHE A 941THR A 945VAL A 954PHE A 956 | NoneECV A1101 (-4.3A)ECV A1101 (-3.2A)NoneECV A1101 ( 4.7A) | 0.44A | 4ltwA-5mwpA:38.0 | 4ltwA-5mwpA:47.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tus | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASELARGE SUBUNIT (Homo sapiens) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 4 | TRP A 581ALA A 700THR A 470VAL A 474 | None | 0.99A | 4ltwA-5tusA:undetectable | 4ltwA-5tusA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uah | RNA POLYMERASE SIGMAFACTOR RPOD (Escherichiacoli) |
PF00140(Sigma70_r1_2)PF04539(Sigma70_r3)PF04542(Sigma70_r2)PF04545(Sigma70_r4)PF04546(Sigma70_ner) | 4 | MET F 322ALA F 321PHE F 316PHE F 306 | None | 0.96A | 4ltwA-5uahF:undetectable | 4ltwA-5uahF:16.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uc1 | GLUCOCORTICOIDRECEPTOR (Heterocephalusglaber) |
no annotation | 4 | TRP A 596MET A 600ALA A 601MET A 642 | NoneNoneCPS A 803 ( 3.9A)486 A 801 ( 3.8A) | 0.41A | 4ltwA-5uc1A:25.2 | 4ltwA-5uc1A:61.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ufs | ANCESTRALGLUCOCORTICOIDRECEPTOR2 (unidentified) |
PF00104(Hormone_recep) | 7 | TRP A 69ALA A 74MET A 115PHE A 204THR A 208VAL A 216PHE A 218 | None1TA A 301 ( 3.7A)1TA A 301 ( 2.8A)1TA A 301 (-3.7A)1TA A 301 (-3.0A)1TA A 301 (-4.3A)1TA A 301 (-4.0A) | 0.62A | 4ltwA-5ufsA:38.4 | 4ltwA-5ufsA:73.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ufs | ANCESTRALGLUCOCORTICOIDRECEPTOR2 (unidentified) |
PF00104(Hormone_recep) | 7 | TRP A 69MET A 73ALA A 74MET A 115THR A 208VAL A 216PHE A 218 | None1TA A 301 (-4.2A)1TA A 301 ( 3.7A)1TA A 301 ( 2.8A)1TA A 301 (-3.0A)1TA A 301 (-4.3A)1TA A 301 (-4.0A) | 0.68A | 4ltwA-5ufsA:38.4 | 4ltwA-5ufsA:73.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ugj | 4-HYDROXY-TETRAHYDRODIPICOLINATEREDUCTASE (Neisseriameningitidis) |
no annotation | 4 | ALA A 241MET A 15THR A 167PHE A 134 | None | 1.03A | 4ltwA-5ugjA:undetectable | 4ltwA-5ugjA:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1w | GLYCOSIDE HYDROLASE (Bacillushalodurans) |
PF03639(Glyco_hydro_81) | 4 | PHE A 306THR A 304VAL A 269PHE A 184 | NoneNoneEDO A 815 (-4.4A)None | 1.03A | 4ltwA-5v1wA:undetectable | 4ltwA-5v1wA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v9x | ATP-DEPENDENT DNAHELICASE (Mycolicibacteriumsmegmatis) |
no annotation | 4 | MET A 246ALA A 247THR A 616VAL A 612 | None | 0.86A | 4ltwA-5v9xA:undetectable | 4ltwA-5v9xA:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xkt | UREASE ACCESSORYPROTEIN UREG (Klebsiellapneumoniae) |
no annotation | 4 | MET A 31ALA A 30THR A 180PHE A 147 | None | 0.80A | 4ltwA-5xktA:undetectable | 4ltwA-5xktA:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ygk | - (-) |
no annotation | 4 | ALA A 52PHE A 36VAL A 45PHE A 115 | None | 0.84A | 4ltwA-5ygkA:undetectable | 4ltwA-5ygkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b82 | CYTOCHROME P450,FAMILY 17, SUBFAMILYA, POLYPEPTIDE 1 (Danio rerio) |
no annotation | 4 | PHE A 208THR A 189VAL A 315PHE A 311 | NoneNoneNoneACT A 603 ( 4.4A) | 0.89A | 4ltwA-6b82A:2.0 | 4ltwA-6b82A:13.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6chj | DIACYLGLYCEROLO-ACYLTRANSFERASE (Marinobacterhydrocarbonoclasticus) |
no annotation | 4 | ALA A 313MET A 333VAL A 421PHE A 423 | None | 0.86A | 4ltwA-6chjA:undetectable | 4ltwA-6chjA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g47 | FIBER-1 (HumanmastadenovirusG) |
no annotation | 4 | ALA A 332PHE A 253VAL A 232PHE A 357 | None | 0.94A | 4ltwA-6g47A:undetectable | 4ltwA-6g47A:11.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gne | - (-) |
no annotation | 4 | ALA A 401PHE A 356THR A 349PHE A 474 | None | 0.69A | 4ltwA-6gneA:undetectable | 4ltwA-6gneA:undetectable |