SIMILAR PATTERNS OF AMINO ACIDS FOR 4LTW_A_486A302_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bqg | D-GLUCARATEDEHYDRATASE (Pseudomonasputida) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 262VAL A 226LEU A 217ILE A 223ALA A 251 | None | 1.06A | 4ltwA-1bqgA:undetectable | 4ltwA-1bqgA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dl5 | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Thermotogamaritima) |
PF01135(PCMT) | 5 | VAL A 120LEU A 102ILE A 125ILE A 25ALA A 21 | None | 0.96A | 4ltwA-1dl5A:undetectable | 4ltwA-1dl5A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gpe | PROTEIN (GLUCOSEOXIDASE) (Penicilliumamagasakiense) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | LEU A 43VAL A 39ILE A 29GLU A 288ALA A 285 | None | 1.09A | 4ltwA-1gpeA:undetectable | 4ltwA-1gpeA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyh | L-2-HYDROXYISOCAPROATE DEHYDROGENASE (Weissellaconfusa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | LEU A 40VAL A 36ILE A 26ILE A 24ALA A 90 | None | 0.99A | 4ltwA-1hyhA:undetectable | 4ltwA-1hyhA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmo | HEPARIN COFACTOR II (Homo sapiens) |
PF00079(Serpin) | 5 | LEU A 386LEU A 457MET A 471ILE A 134ILE A 139 | None | 1.09A | 4ltwA-1jmoA:undetectable | 4ltwA-1jmoA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jpu | GLYCEROLDEHYDROGENASE (Geobacillusstearothermophilus) |
PF00465(Fe-ADH) | 5 | LEU A 27LEU A 99ILE A 91ILE A 89ALA A 111 | None | 0.98A | 4ltwA-1jpuA:undetectable | 4ltwA-1jpuA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgr | PROTEIN (IMPORTINBETA SUBUNIT) (Homo sapiens) |
PF03810(IBN_N)PF13513(HEAT_EZ) | 5 | LEU A 166ILE A 157GLU A 172ILE A 173ALA A 176 | None | 0.93A | 4ltwA-1qgrA:undetectable | 4ltwA-1qgrA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rr9 | ATP-DEPENDENTPROTEASE LA (Escherichiacoli) |
PF05362(Lon_C) | 5 | LEU A 630GLN A 597MET A 634ILE A 638ALA A 641 | None | 1.06A | 4ltwA-1rr9A:undetectable | 4ltwA-1rr9A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s35 | SPECTRIN BETA CHAIN,ERYTHROCYTE (Homo sapiens) |
PF00435(Spectrin) | 5 | LEU A1153VAL A1084LEU A1100ILE A1106ILE A1110 | NoneSO4 A 301 ( 4.6A)NoneNoneNone | 0.87A | 4ltwA-1s35A:undetectable | 4ltwA-1s35A:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uyv | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF01039(Carboxyl_trans) | 5 | LEU A1978VAL A2003ILE A1949ILE A1936ALA A1935 | None | 1.03A | 4ltwA-1uyvA:undetectable | 4ltwA-1uyvA:15.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wnb | PUTATIVE BETAINEALDEHYDEDEHYDROGENASE (Escherichiacoli) |
PF00171(Aldedh) | 5 | LEU A 159ILE A 74GLU A 100ILE A 101ALA A 103 | None | 1.03A | 4ltwA-1wnbA:undetectable | 4ltwA-1wnbA:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wpw | 3-ISOPROPYLMALATEDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00180(Iso_dh) | 5 | LEU A 54GLN A 8ILE A 7ILE A 62ALA A 65 | None | 0.91A | 4ltwA-1wpwA:undetectable | 4ltwA-1wpwA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 509LEU A 350GLN A 353MET A 354GLN A 358ALA A 516 | None | 1.43A | 4ltwA-1xb7A:26.7 | 4ltwA-1xb7A:25.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yp0 | NUCLEAR RECEPTORSUBFAMILY 5, GROUPA, MEMBER 1 (Mus musculus) |
PF00104(Hormone_recep) | 6 | VAL A 278GLN A 295MET A 296GLN A 300GLU A 455ALA A 459 | None | 0.99A | 4ltwA-1yp0A:22.8 | 4ltwA-1yp0A:27.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 712VAL A 716GLN A 733ILE A 737MET A 894GLU A 897 | None | 0.87A | 4ltwA-2ax9A:36.1 | 4ltwA-2ax9A:60.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 712VAL A 716GLN A 733MET A 894GLU A 897ILE A 898 | None | 1.11A | 4ltwA-2ax9A:36.1 | 4ltwA-2ax9A:60.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 712VAL A 716LYS A 720ILE A 737MET A 894GLU A 897 | None | 1.18A | 4ltwA-2ax9A:36.1 | 4ltwA-2ax9A:60.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ax9 | ANDROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 712VAL A 716LYS A 720MET A 894GLU A 897ILE A 898 | None | 1.27A | 4ltwA-2ax9A:36.1 | 4ltwA-2ax9A:60.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3o | TYROSINE-PROTEINPHOSPHATASE,NON-RECEPTOR TYPE 6 (Homo sapiens) |
PF00017(SH2)PF00102(Y_phosphatase) | 5 | VAL A 465LEU A 251ILE A 508ILE A 512ALA A 221 | None | 1.03A | 4ltwA-2b3oA:undetectable | 4ltwA-2b3oA:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dj6 | HYPOTHETICAL PROTEINPH0634 (Pyrococcushorikoshii) |
PF01242(PTPS) | 5 | LEU A 52VAL A 56LEU A 103ILE A 88ILE A 37 | LEU A 52 ( 0.6A)VAL A 56 ( 0.6A)LEU A 103 ( 0.6A)ILE A 88 ( 0.7A)ILE A 37 ( 0.7A) | 1.05A | 4ltwA-2dj6A:undetectable | 4ltwA-2dj6A:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 276LEU A 294GLN A 297MET A 298GLN A 302 | OHT A 500 (-4.9A)NoneNoneNoneNone | 0.70A | 4ltwA-2gpvA:26.4 | 4ltwA-2gpvA:27.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h98 | HTH-TYPETRANSCRIPTIONALREGULATOR CATM (Acinetobactersp. ADP1) |
PF03466(LysR_substrate) | 5 | LEU A 142VAL A 273ILE A 282ILE A 285ALA A 287 | None | 1.03A | 4ltwA-2h98A:undetectable | 4ltwA-2h98A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnh | DNA POLYMERASE IIIALPHA SUBUNIT (Escherichiacoli) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 6 | VAL A 676LEU A 702GLN A 695MET A 691ILE A 684ALA A 752 | None | 1.28A | 4ltwA-2hnhA:undetectable | 4ltwA-2hnhA:15.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i9x | PUTATIVE SEPTATIONPROTEIN SPOVG (Staphylococcusepidermidis) |
PF04026(SpoVG) | 5 | LEU A 34VAL A 45GLN A 70ILE A 72ILE A 23 | None | 1.09A | 4ltwA-2i9xA:undetectable | 4ltwA-2i9xA:15.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inp | PHENOL HYDROXYLASECOMPONENT PHL (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox) | 5 | VAL C 246LEU C 126ILE C 170ILE C 174ALA C 181 | None | 0.93A | 4ltwA-2inpC:undetectable | 4ltwA-2inpC:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ogi | HYPOTHETICAL PROTEINSAG1661 (Streptococcusagalactiae) |
PF01966(HD) | 5 | VAL A 33LEU A 127GLU A 164ILE A 137ALA A 160 | None | 1.09A | 4ltwA-2ogiA:undetectable | 4ltwA-2ogiA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p3e | DIAMINOPIMELATEDECARBOXYLASE (Aquifexaeolicus) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 5 | LEU A 369VAL A 295ILE A 307GLU A 361ILE A 360 | None | 1.09A | 4ltwA-2p3eA:undetectable | 4ltwA-2p3eA:20.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q3y | ANCESTRAL CORTICIODRECEPTOR (unidentified) |
PF00104(Hormone_recep) | 7 | VAL A 44GLN A 61ILE A 65GLN A 66MET A 222GLU A 225ILE A 226 | None | 0.97A | 4ltwA-2q3yA:40.6 | 4ltwA-2q3yA:90.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q3y | ANCESTRAL CORTICIODRECEPTOR (unidentified) |
PF00104(Hormone_recep) | 7 | VAL A 44LEU A 58GLN A 61MET A 62ILE A 65GLN A 66GLU A 225 | None | 0.82A | 4ltwA-2q3yA:40.6 | 4ltwA-2q3yA:90.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvg | KINESIN-2 (Giardiaintestinalis) |
PF00225(Kinesin) | 5 | LEU A 326VAL A 39ILE A 28ILE A 312ALA A 101 | NoneNoneNoneNoneADP A1351 (-4.3A) | 1.09A | 4ltwA-2vvgA:undetectable | 4ltwA-2vvgA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvg | KINESIN-2 (Giardiaintestinalis) |
PF00225(Kinesin) | 5 | LEU A 326VAL A 39LEU A 25ILE A 28ILE A 312 | None | 0.79A | 4ltwA-2vvgA:undetectable | 4ltwA-2vvgA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w48 | SORBITOL OPERONREGULATOR (Klebsiellapneumoniae) |
PF04198(Sugar-bind)PF13936(HTH_38) | 5 | LEU A 179ILE A 143MET A 269GLU A 268ILE A 267 | MPD A1317 (-3.9A)NoneNoneNoneNone | 0.97A | 4ltwA-2w48A:undetectable | 4ltwA-2w48A:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2we8 | XANTHINEDEHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF02625(XdhC_CoxI)PF13478(XdhC_C) | 5 | LEU A 295VAL A 291GLN A 263ILE A 269ALA A 268 | None | 1.04A | 4ltwA-2we8A:undetectable | 4ltwA-2we8A:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhs | NUCLEAR HORMONERECEPTOR FTZ-F1 (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 6 | LEU A 841VAL A 845GLN A 862MET A 863GLN A 867ALA A1023 | None | 0.63A | 4ltwA-2xhsA:19.9 | 4ltwA-2xhsA:28.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xhs | NUCLEAR HORMONERECEPTOR FTZ-F1 (Drosophilamelanogaster) |
PF00104(Hormone_recep) | 5 | LEU A1016GLN A 862MET A 863GLN A 867ALA A1023 | None | 0.94A | 4ltwA-2xhsA:19.9 | 4ltwA-2xhsA:28.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y30 | PUTATIVE REPRESSORSIMREG2 (Streptomycesantibioticus) |
PF00440(TetR_N)PF02909(TetR_C) | 5 | LEU A 117VAL A 79LEU A 133ILE A 83GLU A 165 | None | 0.89A | 4ltwA-2y30A:2.0 | 4ltwA-2y30A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywr | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Aquifexaeolicus) |
PF00551(Formyl_trans_N) | 5 | LEU A 15VAL A 6LEU A 2ILE A 31ILE A 19 | None | 0.98A | 4ltwA-2ywrA:undetectable | 4ltwA-2ywrA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3av6 | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 5 | LEU A1268MET A1172GLU A1171ILE A1170ALA A1169 | NoneSAM A 1 (-3.6A)SAM A 1 (-2.6A)NoneNone | 0.97A | 4ltwA-3av6A:undetectable | 4ltwA-3av6A:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efb | PROBABLE SOR-OPERONREGULATOR (Shigellaflexneri) |
PF04198(Sugar-bind) | 5 | LEU A 129ILE A 93MET A 219GLU A 218ILE A 217 | None | 1.07A | 4ltwA-3efbA:undetectable | 4ltwA-3efbA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd5 | SELENIDE, WATERDIKINASE 1 (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | LEU A 203LEU A 328ILE A 354ILE A 271ALA A 275 | None | 0.92A | 4ltwA-3fd5A:undetectable | 4ltwA-3fd5A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fi1 | NA(+)/H(+)ANTIPORTER NHAA (Escherichiacoli) |
PF06965(Na_H_antiport_1) | 5 | LEU A 348VAL A 224ILE A 168ILE A 345ALA A 130 | None | 1.08A | 4ltwA-3fi1A:undetectable | 4ltwA-3fi1A:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g9q | FERRICHROME-BINDINGPROTEIN (Bacillussubtilis) |
PF01497(Peripla_BP_2) | 5 | LEU A 222LEU A 302GLN A 305ILE A 309ILE A 183 | None | 0.95A | 4ltwA-3g9qA:undetectable | 4ltwA-3g9qA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3glb | HTH-TYPETRANSCRIPTIONALREGULATOR CATM (Acinetobactersp. ADP1) |
PF03466(LysR_substrate) | 5 | LEU A 142VAL A 273ILE A 282ILE A 285ALA A 287 | None | 1.03A | 4ltwA-3glbA:undetectable | 4ltwA-3glbA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iqd | OCTOPINEDEHYDROGENASE (Pecten maximus) |
PF02317(Octopine_DH) | 5 | LEU B 269ILE B 205MET B 261ILE B 260ALA B 344 | None | 0.99A | 4ltwA-3iqdB:undetectable | 4ltwA-3iqdB:21.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kba | PROGESTERONERECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 726VAL A 730GLN A 747ILE A 751MET A 908ALA A 915 | None | 0.69A | 4ltwA-3kbaA:36.7 | 4ltwA-3kbaA:66.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kba | PROGESTERONERECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | VAL A 730GLN A 747ILE A 751GLN A 752ALA A 915 | None | 0.90A | 4ltwA-3kbaA:36.7 | 4ltwA-3kbaA:66.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lcm | PUTATIVEOXIDOREDUCTASE (Streptococcusmutans) |
PF02525(Flavodoxin_2) | 5 | LEU A 27VAL A 23ILE A 5ILE A 3ALA A 74 | None | 1.00A | 4ltwA-3lcmA:undetectable | 4ltwA-3lcmA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q9t | CHOLINEDEHYDROGENASE ANDRELATEDFLAVOPROTEINS (Aspergillusoryzae) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | LEU A 26VAL A 22ILE A 12GLU A 262ALA A 259 | None | 1.00A | 4ltwA-3q9tA:undetectable | 4ltwA-3q9tA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qw4 | UMP SYNTHASE (Leishmaniadonovani) |
PF00156(Pribosyltran)PF00215(OMPdecase) | 5 | LEU B 424VAL B 401LEU B 293ILE B 288ILE B 286 | None | 0.94A | 4ltwA-3qw4B:undetectable | 4ltwA-3qw4B:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ta6 | TRIOSEPHOSPHATEISOMERASE (Mycobacteriumtuberculosis) |
PF00121(TIM) | 5 | LEU A 156VAL A 130LEU A 6ILE A 169ALA A 208 | None | 1.09A | 4ltwA-3ta6A:undetectable | 4ltwA-3ta6A:22.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqr | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Coxiellaburnetii) |
PF00551(Formyl_trans_N) | 5 | LEU A 19VAL A 10LEU A 6ILE A 34ILE A 23 | None | 1.01A | 4ltwA-3tqrA:undetectable | 4ltwA-3tqrA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3twk | FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1 (Arabidopsisthaliana) |
PF01149(Fapy_DNA_glyco)PF06831(H2TH) | 5 | LEU A 64LEU A 4GLU A 15ILE A 14ALA A 13 | None | 1.00A | 4ltwA-3twkA:undetectable | 4ltwA-3twkA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tx7 | NUCLEAR RECEPTORSUBFAMILY 5 GROUP AMEMBER 2 (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU B 353VAL B 357GLN B 374GLN B 379GLU B 534ALA B 538 | None | 0.52A | 4ltwA-3tx7B:19.4 | 4ltwA-3tx7B:24.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3unv | ADMH (Pantoeaagglomerans) |
PF00221(Lyase_aromatic) | 5 | LEU A 347LEU A 52GLU A 39ILE A 40ALA A 43 | None | 0.99A | 4ltwA-3unvA:undetectable | 4ltwA-3unvA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ups | IOJAP-LIKE PROTEIN (Zymomonasmobilis) |
PF02410(RsfS) | 5 | LEU A 92LEU A 22ILE A 100ILE A 99ALA A 47 | None | 0.97A | 4ltwA-3upsA:undetectable | 4ltwA-3upsA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vr5 | V-TYPE SODIUM ATPASESUBUNIT B (Enterococcushirae) |
PF00006(ATP-synt_ab)PF02874(ATP-synt_ab_N) | 5 | LEU D 141LEU D 304ILE D 301GLN D 300ALA D 288 | None | 1.09A | 4ltwA-3vr5D:undetectable | 4ltwA-3vr5D:18.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vsk | PENICILLIN-BINDINGPROTEIN 3 (Staphylococcusaureus) |
PF00905(Transpeptidase)PF03717(PBP_dimer) | 5 | LEU A 400VAL A 579ILE A 586GLN A 590ILE A 589 | None | 0.94A | 4ltwA-3vskA:undetectable | 4ltwA-3vskA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuq | BOTULINUM NEUROTOXINTYPE B (Clostridiumbotulinum) |
PF01742(Peptidase_M27)PF07952(Toxin_trans) | 5 | LEU A 590VAL A 604LEU A 583ILE A 588ILE A 768 | None | 1.03A | 4ltwA-3zuqA:undetectable | 4ltwA-3zuqA:13.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0t | PUP--PROTEIN LIGASE (Corynebacteriumglutamicum) |
PF03136(Pup_ligase) | 5 | LEU A 324ILE A 158GLU A 335ILE A 334ALA A 333 | None | 1.05A | 4ltwA-4b0tA:undetectable | 4ltwA-4b0tA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvh | ISOPRENOID SYNTHASEDOMAIN-CONTAININGPROTEIN (Homo sapiens) |
PF01128(IspD) | 6 | LEU A 134VAL A 50LEU A 167ILE A 154ILE A 222ALA A 179 | None | 1.25A | 4ltwA-4cvhA:undetectable | 4ltwA-4cvhA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d86 | POLY [ADP-RIBOSE]POLYMERASE 14 (Homo sapiens) |
PF01661(Macro) | 5 | LEU A 804VAL A 806LEU A 930ILE A 941ALA A 940 | None | 1.08A | 4ltwA-4d86A:undetectable | 4ltwA-4d86A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iru | LEPB (Legionellapneumophila) |
no annotation | 5 | LEU A 521ILE A 467GLU A 514ILE A 517ALA A 513 | None | 1.04A | 4ltwA-4iruA:undetectable | 4ltwA-4iruA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0d | N-ACETYLMURAMIC ACID6-PHOSPHATE ETHERASE (Haemophilusinfluenzae) |
PF01380(SIS) | 5 | LEU A 214VAL A 210ILE A 170ILE A 168ALA A 182 | None | 0.98A | 4ltwA-4m0dA:undetectable | 4ltwA-4m0dA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbr | SERINE-RICH REPEATPROTEIN 2 (Streptococcusagalactiae) |
PF10425(SdrG_C_C) | 5 | LEU A 346VAL A 364LEU A 242ILE A 284ILE A 344 | None | 1.02A | 4ltwA-4mbrA:undetectable | 4ltwA-4mbrA:20.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 5 | LEU A 291GLN A 312ILE A 316GLU A 468ALA A 472 | None | 0.79A | 4ltwA-4n1yA:29.6 | 4ltwA-4n1yA:31.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 5 | LEU A 291LEU A 309GLN A 312GLU A 468ALA A 472 | None | 0.67A | 4ltwA-4n1yA:29.6 | 4ltwA-4n1yA:31.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 5 | LEU A 291LYS A 299GLN A 312ILE A 316ALA A 472 | None | 0.88A | 4ltwA-4n1yA:29.6 | 4ltwA-4n1yA:31.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 5 | LEU A 291LYS A 299LEU A 309GLN A 312ALA A 472 | None | 0.83A | 4ltwA-4n1yA:29.6 | 4ltwA-4n1yA:31.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p6w | GLUCOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 7 | VAL A 575LEU A 589GLN A 592MET A 593GLN A 597GLU A 755ILE A 756 | None | 0.75A | 4ltwA-4p6wA:36.6 | 4ltwA-4p6wA:62.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q73 | PROLINEDEHYDROGENASE (Bradyrhizobiumdiazoefficiens) |
PF00171(Aldedh)PF01619(Pro_dh)PF14850(Pro_dh-DNA_bdg) | 6 | LEU A 916VAL A 918GLN A 801ILE A 766ILE A 907ALA A 906 | None | 1.30A | 4ltwA-4q73A:undetectable | 4ltwA-4q73A:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qkf | ALPHA-KETOGLUTARATE-DEPENDENTDIOXYGENASE ALKBHOMOLOG 7,MITOCHONDRIAL (Homo sapiens) |
PF13532(2OG-FeII_Oxy_2) | 5 | LEU A 110LEU A 145ILE A 179ILE A 70ALA A 69 | OGA A 301 ( 4.6A)NoneNoneNoneNone | 1.09A | 4ltwA-4qkfA:undetectable | 4ltwA-4qkfA:23.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | VAL A 781GLN A 798ILE A 802GLN A 803GLU A 962ILE A 963 | None | 0.50A | 4ltwA-4udbA:36.1 | 4ltwA-4udbA:65.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | VAL A 781LEU A 795GLN A 798ILE A 802GLN A 803 | None | 0.73A | 4ltwA-4udbA:36.1 | 4ltwA-4udbA:65.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4usq | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE (Cellvibrio sp.BR) |
PF13738(Pyr_redox_3) | 5 | LEU A 32VAL A 28ILE A 18ILE A 16ALA A 130 | None | 0.99A | 4ltwA-4usqA:undetectable | 4ltwA-4usqA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxx | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Homo sapiens) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 5 | LEU A1265MET A1169GLU A1168ILE A1167ALA A1166 | NoneSAH A1706 (-3.9A)SAH A1706 (-2.8A)NoneNone | 1.08A | 4ltwA-4wxxA:undetectable | 4ltwA-4wxxA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy9 | PUTATIVE MCP-TYPESIGNAL TRANSDUCTIONPROTEIN (Campylobacterjejuni) |
PF02743(dCache_1) | 5 | LEU A 242VAL A 240LEU A 46ILE A 277ALA A 276 | None | 1.08A | 4ltwA-4wy9A:undetectable | 4ltwA-4wy9A:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xcw | MOLYBDOPTERINADENYLYLTRANSFERASE (Helicobacterpylori) |
PF00994(MoCF_biosynth) | 6 | LEU A 69VAL A 71GLN A 119ILE A 130ILE A 150ALA A 149 | None | 1.20A | 4ltwA-4xcwA:undetectable | 4ltwA-4xcwA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y1p | 3-ISOPROPYLMALATEDEHYDROGENASE (Sulfolobusacidocaldarius) |
PF00180(Iso_dh) | 5 | LEU A 55GLN A 9ILE A 8ILE A 63ALA A 66 | None | 0.90A | 4ltwA-4y1pA:undetectable | 4ltwA-4y1pA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y85 | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 8 (Homo sapiens) |
PF00069(Pkinase) | 6 | VAL A 249LEU A 273ILE A 181GLN A 182ILE A 190ALA A 191 | NoneNoneNoneNoneNone499 A 401 ( 4.6A) | 1.35A | 4ltwA-4y85A:undetectable | 4ltwA-4y85A:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zr8 | UROPORPHYRINOGENDECARBOXYLASE (Acinetobacterbaumannii) |
PF01208(URO-D) | 5 | LEU A 193VAL A 189MET A 227ILE A 230ALA A 264 | None | 1.07A | 4ltwA-4zr8A:undetectable | 4ltwA-4zr8A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aek | SENTRIN-SPECIFICPROTEASE 2 (Homo sapiens) |
PF02902(Peptidase_C48) | 6 | LEU A 368LEU A 422MET A 372GLU A 375ILE A 376ALA A 379 | None | 1.04A | 4ltwA-5aekA:undetectable | 4ltwA-5aekA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c00 | MDBA PROTEIN (Corynebacteriumdiphtheriae) |
PF13462(Thioredoxin_4) | 5 | VAL A 239ILE A 114GLU A 110ILE A 109ALA A 73 | None | 1.09A | 4ltwA-5c00A:undetectable | 4ltwA-5c00A:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c1b | TRANSITIONALENDOPLASMICRETICULUM ATPASE (Homo sapiens) |
PF00004(AAA)PF02359(CDC48_N)PF02933(CDC48_2)PF09336(Vps4_C) | 5 | LEU A 579GLN A 603ILE A 604ILE A 633ALA A 632 | None | 1.02A | 4ltwA-5c1bA:undetectable | 4ltwA-5c1bA:15.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cml | OSMC FAMILY PROTEIN (Rhodothermusmarinus) |
PF12146(Hydrolase_4) | 6 | LEU A 244VAL A 240LEU A 230ILE A 50ILE A 106ALA A 35 | None | 1.36A | 4ltwA-5cmlA:undetectable | 4ltwA-5cmlA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dkc | PROBABLE GLOBALTRANSCRIPTIONACTIVATOR SNF2L2 (Homo sapiens) |
PF00439(Bromodomain) | 5 | LEU A1383GLN A1386MET A1387ILE A1390MET A1454 | None | 1.03A | 4ltwA-5dkcA:undetectable | 4ltwA-5dkcA:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eqn | FRBJ (Streptomycesrubellomurinus) |
PF02668(TauD) | 6 | LEU A 30VAL A 69MET A 34GLU A 37ILE A 38ALA A 41 | None | 1.17A | 4ltwA-5eqnA:undetectable | 4ltwA-5eqnA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5exr | DNA POLYMERASE ALPHACATALYTIC SUBUNIT (Homo sapiens) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1)PF08996(zf-DNA_Pol) | 5 | LEU C 708VAL C 712ILE C 755ILE C 752ALA C 541 | None | 0.98A | 4ltwA-5exrC:undetectable | 4ltwA-5exrC:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f2v | GTPPYROPHOSPHOKINASEYJBM (Bacillussubtilis) |
no annotation | 5 | LEU V 93VAL V 89LEU V 145ILE V 142ILE V 140 | None | 0.93A | 4ltwA-5f2vV:undetectable | 4ltwA-5f2vV:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fvd | NUCLEOCAPSID (Humanmetapneumovirus) |
PF03246(Pneumo_ncap) | 5 | GLN A 41ILE A 44GLN A 68ILE A 116ALA A 34 | None | 1.06A | 4ltwA-5fvdA:undetectable | 4ltwA-5fvdA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gut | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH) | 5 | LEU A1268MET A1172GLU A1171ILE A1170ALA A1169 | NoneSAH A1701 (-3.8A)SAH A1701 (-2.7A)NoneNone | 0.98A | 4ltwA-5gutA:undetectable | 4ltwA-5gutA:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ibz | UNCHARACTERIZEDPROTEIN (unculturedorganism) |
PF04199(Cyclase) | 5 | VAL A 83LEU A 126GLN A 127ILE A 75ALA A 74 | None | 1.08A | 4ltwA-5ibzA:undetectable | 4ltwA-5ibzA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iud | DNA POLYMERASE ALPHACATALYTIC SUBUNIT (Homo sapiens) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | LEU A 708VAL A 712ILE A 755ILE A 752ALA A 541 | None | 1.01A | 4ltwA-5iudA:undetectable | 4ltwA-5iudA:13.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldw | NADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN8, MITOCHONDRIAL (Bos taurus) |
PF12838(Fer4_7) | 5 | LEU I 155LEU I 82ILE I 131ILE I 111ALA I 91 | NoneSF4 I 202 ( 4.2A)SF4 I 202 (-4.8A)NoneSF4 I 201 ( 4.5A) | 1.08A | 4ltwA-5ldwI:undetectable | 4ltwA-5ldwI:21.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mwp | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
no annotation | 6 | VAL A 781LEU A 795GLN A 798ILE A 802GLN A 803ILE A 963 | None | 0.79A | 4ltwA-5mwpA:38.0 | 4ltwA-5mwpA:47.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ny0 | L. REUTERIS SRRPBINDING REGION (Lactobacillusreuteri) |
no annotation | 5 | LEU A 333VAL A 331ILE A 323ILE A 321ALA A 293 | None | 1.03A | 4ltwA-5ny0A:undetectable | 4ltwA-5ny0A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udb | DNA REPLICATIONLICENSING FACTORMCM6 (Saccharomycescerevisiae) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 5 | LEU 6 185VAL 6 189ILE 6 140GLN 6 139ILE 6 151 | None | 1.01A | 4ltwA-5udb6:undetectable | 4ltwA-5udb6:13.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ufs | ANCESTRALGLUCOCORTICOIDRECEPTOR2 (unidentified) |
PF00104(Hormone_recep) | 7 | VAL A 44LEU A 58GLN A 61MET A 62GLN A 66GLU A 224ILE A 225 | None | 0.77A | 4ltwA-5ufsA:38.4 | 4ltwA-5ufsA:73.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xog | DNA-DIRECTED RNAPOLYMERASE SUBUNITBETA (Komagataellaphaffii) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 5 | LEU B1010GLN B 770GLN B 986ILE B1012ALA B1016 | None | 0.94A | 4ltwA-5xogB:undetectable | 4ltwA-5xogB:11.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c43 | GAMMA-AMINOBUTYRALDEHYDE DEHYDROGENASE (Salmonellaenterica) |
no annotation | 5 | LEU A 159ILE A 74GLU A 100ILE A 101ALA A 103 | None | 1.07A | 4ltwA-6c43A:undetectable | 4ltwA-6c43A:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfp | VCA0883 (Vibrio cholerae) |
no annotation | 5 | VAL A 211ILE A 250GLN A 249ILE A 186ALA A 185 | None | 1.06A | 4ltwA-6dfpA:3.3 | 4ltwA-6dfpA:13.82 |