SIMILAR PATTERNS OF AMINO ACIDS FOR 4LRH_D_FOLD301_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4kmz	FOLATE RECEPTOR BETA (Homo sapiens)	PF03024 (Folate_rec)	11	TYR A 76 ASP A 97 TYR A 101 GLN A 116 SER A 117 TRP A 118 ARG A 119 ARG A 122 TRP A 154 TRP A 187 TYR A 191	FOL A 301 (-3.8A) FOL A 301 (-2.8A) FOL A 301 (-3.8A) FOL A 301 ( 4.8A) FOL A 301 (-3.5A) FOL A 301 (-4.0A) FOL A 301 (-3.0A) FOL A 301 ( 4.4A) None FOL A 301 (-3.5A) FOL A 301 (-4.1A)	0.49A	4lrhD-4kmzA: 34.8	4lrhD-4kmzA: 77.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4lrh	FOLATE RECEPTOR ALPHA (Homo sapiens)	PF03024 (Folate_rec)	6	ASP A 81 GLN A 100 ARG A 106 LYS A 136 TRP A 138 TRP A 171	FOL A 301 (-2.7A) FOL A 301 (-4.3A) FOL A 301 (-3.8A) FOL A 301 (-4.0A) None FOL A 301 (-3.7A)	1.44A	4lrhD-4lrhA: 37.2	4lrhD-4lrhA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4lrh	FOLATE RECEPTOR ALPHA (Homo sapiens)	PF03024 (Folate_rec)	12	TYR A 60 ASP A 81 TYR A 85 GLN A 100 SER A 101 TRP A 102 ARG A 103 ARG A 106 LYS A 136 TRP A 138 TRP A 171 TYR A 175	FOL A 301 (-3.9A) FOL A 301 (-2.7A) FOL A 301 (-4.1A) FOL A 301 (-4.3A) FOL A 301 (-3.5A) FOL A 301 (-4.2A) FOL A 301 (-3.2A) FOL A 301 (-3.8A) FOL A 301 (-4.0A) None FOL A 301 (-3.7A) FOL A 301 (-4.1A)	0.45A	4lrhD-4lrhA: 37.2	4lrhD-4lrhA: 100.00

[["4LRH_D_FOLD301_0","4kmz","Homo sapiens","FOLATE RECEPTOR BETA","PF03024(Folate_rec)",11,"TYR A  76;ASP A  97;TYR A 101;GLN A 116;SER A 117;TRP A 118;ARG A 119;ARG A 122;TRP A 154;TRP A 187;TYR A 191","FOL A 301 (-3.8A);FOL A 301 (-2.8A);FOL A 301 (-3.8A);FOL A 301 ( 4.8A);FOL A 301 (-3.5A);FOL A 301 (-4.0A);FOL A 301 (-3.0A);FOL A 301 ( 4.4A);None;FOL A 301 (-3.5A);FOL A 301 (-4.1A)","0.49A","4lrhD-4kmzA:34.8","4lrhD-4kmzA:77.36"],["4LRH_D_FOLD301_0","4lrh","Homo sapiens","FOLATE RECEPTOR ALPHA","PF03024(Folate_rec)",6,"ASP A  81;GLN A 100;ARG A 106;LYS A 136;TRP A 138;TRP A 171","FOL A 301 (-2.7A);FOL A 301 (-4.3A);FOL A 301 (-3.8A);FOL A 301 (-4.0A);None;FOL A 301 (-3.7A)","1.44A","4lrhD-4lrhA:37.2","4lrhD-4lrhA:100.00"],["4LRH_D_FOLD301_0","4lrh","Homo sapiens","FOLATE RECEPTOR ALPHA","PF03024(Folate_rec)",12,"TYR A  60;ASP A  81;TYR A  85;GLN A 100;SER A 101;TRP A 102;ARG A 103;ARG A 106;LYS A 136;TRP A 138;TRP A 171;TYR A 175","FOL A 301 (-3.9A);FOL A 301 (-2.7A);FOL A 301 (-4.1A);FOL A 301 (-4.3A);FOL A 301 (-3.5A);FOL A 301 (-4.2A);FOL A 301 (-3.2A);FOL A 301 (-3.8A);FOL A 301 (-4.0A);None;FOL A 301 (-3.7A);FOL A 301 (-4.1A)","0.45A","4lrhD-4lrhA:37.2","4lrhD-4lrhA:100.00"]]