SIMILAR PATTERNS OF AMINO ACIDS FOR 4LNX_A_T44A501_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4x PROTEIN
(2-HYDROXY-6-OXO-6-P
HENYLHEXA-2,4-DIENOA
TE HYDROLASE)

(Rhodococcus
jostii) 		PF12697
(Abhydrolase_6) 		4 GLU A   8
GLN A  70
VAL A 189
ARG A 186
 None
 1.15A 4lnxA-1c4xA:
0.0		 4lnxA-1c4xA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cg8 PROTEIN (HEMOGLOBIN)

(Dasyatis akajei) 		PF00042
(Globin) 		4 SER A   3
GLN A   5
VAL A 120
THR A 121
 None
 1.27A 4lnxA-1cg8A:
0.5		 4lnxA-1cg8A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgs DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 GLU A 189
VAL A 210
THR A 211
ARG A 214
 None
 1.26A 4lnxA-1dgsA:
0.0		 4lnxA-1dgsA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8w NADH PEROXIDASE

(Enterococcus
faecalis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 GLU A  27
GLN A  29
VAL A  91
THR A  90
 None
 1.31A 4lnxA-1f8wA:
0.0		 4lnxA-1f8wA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5x GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Thermotoga
maritima) 		PF01380
(SIS) 		4 SER A  51
GLU A 217
VAL A 328
THR A 327
 None
 1.32A 4lnxA-1j5xA:
0.0		 4lnxA-1j5xA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k7j PROTEIN YCIO

(Escherichia
coli) 		PF01300
(Sua5_yciO_yrdC) 		4 SER A 144
VAL A 184
THR A 183
ARG A 196
 SO4  A 207 (-2.6A)
None
None
SO4  A 207 (-3.1A)
 1.36A 4lnxA-1k7jA:
0.0		 4lnxA-1k7jA:
22.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nav HORMONE RECEPTOR
ALPHA 1, THRA1

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 GLU A 339
GLN A 342
VAL A 371
THR A 372
ARG A 375
 None
 1.12A 4lnxA-1navA:
37.5		 4lnxA-1navA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nav HORMONE RECEPTOR
ALPHA 1, THRA1

(Homo sapiens) 		PF00104
(Hormone_recep) 		5 SER A 326
GLU A 339
GLN A 342
THR A 372
ARG A 375
 None
 1.35A 4lnxA-1navA:
37.5		 4lnxA-1navA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1q4x THYROID HORMONE
RECEPTOR BETA-1

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 SER A 380
GLN A 396
VAL A 425
THR A 426
 None
 0.85A 4lnxA-1q4xA:
36.8		 4lnxA-1q4xA:
81.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpp PAPD CHAPERONE

(Escherichia
coli) 		PF00345
(PapD_N)
PF02753
(PapD_C) 		4 SER A  84
GLU A  83
VAL A  50
THR A  71
 None
 1.10A 4lnxA-1qppA:
undetectable		 4lnxA-1qppA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w7c LYSYL OXIDASE

(Komagataella
pastoris) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF09248
(DUF1965) 		4 GLU A 374
GLN A 378
VAL A 668
THR A 161
 None
 1.36A 4lnxA-1w7cA:
undetectable		 4lnxA-1w7cA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2awa DNA POLYMERASE III,
BETA CHAIN

(Streptococcus
pneumoniae) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 SER A  74
GLU A  98
VAL A  34
THR A  33
 None
 1.38A 4lnxA-2awaA:
undetectable		 4lnxA-2awaA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c11 MEMBRANE COPPER
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 GLU A 100
VAL A 155
THR A 156
ARG A 159
 None
None
NAG  A1730 ( 4.3A)
None
 1.25A 4lnxA-2c11A:
undetectable		 4lnxA-2c11A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cge ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90) 		4 SER A 450
GLU A 453
THR A 462
ARG A 463
 None
 1.38A 4lnxA-2cgeA:
undetectable		 4lnxA-2cgeA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1p HYPOTHETICAL PROTEIN
YHEL
HYPOTHETICAL UPF0163
PROTEIN YHEN

(Escherichia
coli) 		PF02635
(DrsE)
PF04077
(DsrH) 		4 GLN A  15
VAL C  34
THR C  35
ARG C  64
 None
 1.25A 4lnxA-2d1pA:
undetectable		 4lnxA-2d1pA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dax PROTEIN C21ORF6

(Homo sapiens) 		PF05773
(RWD) 		4 SER A  96
GLN A 104
VAL A 132
THR A 129
 None
 1.37A 4lnxA-2daxA:
undetectable		 4lnxA-2daxA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 SER A 340
GLU A 234
GLN A 339
VAL A 361
 None
 1.24A 4lnxA-2gmhA:
undetectable		 4lnxA-2gmhA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph1 NUCLEOTIDE-BINDING
PROTEIN

(Archaeoglobus
fulgidus) 		PF10609
(ParA) 		4 SER A  25
GLU A 164
VAL A  35
THR A  34
 None
 0.94A 4lnxA-2ph1A:
undetectable		 4lnxA-2ph1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph1 NUCLEOTIDE-BINDING
PROTEIN

(Archaeoglobus
fulgidus) 		PF10609
(ParA) 		4 SER A 160
GLU A 164
VAL A  35
THR A  36
 None
 1.39A 4lnxA-2ph1A:
undetectable		 4lnxA-2ph1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 GLN A 101
VAL A 154
THR A 155
ARG A 158
 None
 0.97A 4lnxA-2pncA:
undetectable		 4lnxA-2pncA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 GLU A  99
VAL A 154
THR A 155
ARG A 158
 None
 1.36A 4lnxA-2pncA:
undetectable		 4lnxA-2pncA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ptz ENOLASE

(Trypanosoma
brucei) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 SER A 366
GLN A 392
VAL A 288
THR A 313
 None
 1.31A 4lnxA-2ptzA:
undetectable		 4lnxA-2ptzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtk SERINE/THREONINE-PRO
TEIN KINASE 11

(Homo sapiens) 		PF00069
(Pkinase) 		4 SER C 216
GLN C 220
VAL C 243
THR C 244
 None
 0.97A 4lnxA-2wtkC:
undetectable		 4lnxA-2wtkC:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzf GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		4 SER A 206
GLU A 237
VAL A 312
THR A 311
 None
 1.38A 4lnxA-2wzfA:
undetectable		 4lnxA-2wzfA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzg GLUCOSYLTRANSFERASE

(Legionella
pneumophila) 		PF16849
(Glyco_transf_88) 		4 SER A 206
GLU A 237
VAL A 312
THR A 311
 None
 1.36A 4lnxA-2wzgA:
undetectable		 4lnxA-2wzgA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xkk TOPOISOMERASE IV

(Acinetobacter
baumannii) 		PF00521
(DNA_topoisoIV)
PF00986
(DNA_gyraseB_C)
PF01751
(Toprim) 		4 SER A1460
GLU A1459
VAL A1362
THR A1363
 None
 0.99A 4lnxA-2xkkA:
undetectable		 4lnxA-2xkkA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE
IRON-SULFUR
ATP-BINDING PROTEIN
LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT B

(Prochlorococcus
marinus) 		PF00142
(Fer4_NifH)
PF00148
(Oxidored_nitro)
PF08369
(PCP_red) 		4 GLU D  93
GLN D 103
VAL A 133
THR A 132
 GOL  D1532 (-3.0A)
None
None
None
 1.24A 4lnxA-2ynmD:
undetectable		 4lnxA-2ynmD:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywg GTP-BINDING PROTEIN
LEPA

(Aquifex
aeolicus) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF06421
(LepA_C) 		4 SER A 333
GLU A 331
VAL A 490
THR A 489
 None
 1.33A 4lnxA-2ywgA:
undetectable		 4lnxA-2ywgA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu CROSSOVER JUNCTION
ENDONUCLEASE EME1

(Homo sapiens) 		PF02732
(ERCC4) 		4 GLU B 283
GLN B 285
VAL B 312
THR B 311
 None
 1.29A 4lnxA-2ziuB:
undetectable		 4lnxA-2ziuB:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB

(Neisseria
meningitidis) 		PF01625
(PMSR) 		4 GLU A 335
GLN A 338
VAL A 252
THR A 251
 None
ACT  A1000 (-3.6A)
None
None
 1.28A 4lnxA-3bqhA:
undetectable		 4lnxA-3bqhA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chv PROKARYOTIC DOMAIN
OF UNKNOWN FUNCTION
(DUF849) WITH A TIM
BARREL FOLD

(Ruegeria
pomeroyi) 		PF05853
(BKACE) 		4 SER A 110
GLU A 145
GLN A  85
THR A  16
 None
 1.26A 4lnxA-3chvA:
undetectable		 4lnxA-3chvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzu PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA

(Homo sapiens) 		PF00104
(Hormone_recep)
PF00105
(zf-C4) 		4 SER D 394
GLU D 407
GLN D 410
THR D 440
 None
 1.03A 4lnxA-3dzuD:
22.3		 4lnxA-3dzuD:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fa5 PROTEIN OF UNKNOWN
FUNCTION (DUF849)

(Paracoccus
denitrificans) 		PF05853
(BKACE) 		4 SER A 110
GLU A 145
GLN A  85
THR A  16
 None
 1.29A 4lnxA-3fa5A:
undetectable		 4lnxA-3fa5A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 SER A 382
GLN A 386
VAL A 489
THR A 492
 None
 1.32A 4lnxA-3g25A:
undetectable		 4lnxA-3g25A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdn R-OXYNITRILE LYASE
ISOENZYME 1

(Prunus dulcis) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 SER A 107
GLN A 499
VAL A 141
THR A 144
 None
FAD  A 522 (-4.6A)
None
None
 1.29A 4lnxA-3gdnA:
undetectable		 4lnxA-3gdnA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ikm DNA POLYMERASE
SUBUNIT GAMMA-1

(Homo sapiens) 		PF00476
(DNA_pol_A) 		4 SER A1021
GLU A1016
THR A 851
ARG A 852
 None
 1.32A 4lnxA-3ikmA:
undetectable		 4lnxA-3ikmA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE

(Escherichia
coli) 		PF03710
(GlnE)
PF08335
(GlnD_UR_UTase) 		4 GLN A 917
VAL A 523
THR A 524
ARG A 527
 None
SO4  A   5 ( 4.7A)
None
SO4  A   5 (-3.7A)
 0.93A 4lnxA-3k7dA:
undetectable		 4lnxA-3k7dA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7h INDIAN HEDGEHOG
PROTEIN

(Homo sapiens) 		PF01085
(HH_signal) 		4 SER B  53
GLN B  51
VAL B  45
ARG B 168
 None
 1.34A 4lnxA-3k7hB:
undetectable		 4lnxA-3k7hB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m8u HEME-BINDING PROTEIN
A

(Glaesserella
parasuis) 		PF00496
(SBP_bac_5) 		4 SER A 403
GLU A 397
VAL A 374
THR A 426
 None
 1.25A 4lnxA-3m8uA:
undetectable		 4lnxA-3m8uA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n8u IMELYSIN PEPTIDASE

(Bacteroides
ovatus) 		PF09375
(Peptidase_M75) 		4 SER A  78
GLU A  77
VAL A 257
THR A 254
 None
 1.32A 4lnxA-3n8uA:
undetectable		 4lnxA-3n8uA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pdi NITROGENASE MOFE
COFACTOR
BIOSYNTHESIS PROTEIN
NIFN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro) 		4 GLU B 230
GLN B 171
VAL B 260
THR B 258
 None
 1.37A 4lnxA-3pdiB:
undetectable		 4lnxA-3pdiB:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9t CHOLINE
DEHYDROGENASE AND
RELATED
FLAVOPROTEINS

(Aspergillus
oryzae) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 GLU A 271
GLN A 267
VAL A 245
THR A 246
 ACT  A   1 ( 2.8A)
FAY  A 600 (-3.2A)
None
None
 1.05A 4lnxA-3q9tA:
undetectable		 4lnxA-3q9tA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN

(Bacteroides
caccae) 		PF12667
(NigD_N)
PF17415
(NigD_C) 		4 SER A  78
GLU A  34
VAL A  59
THR A  48
 None
 1.30A 4lnxA-3qwnA:
undetectable		 4lnxA-3qwnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3red HYDROXYNITRILE LYASE

(Prunus mume) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 SER A 107
GLN A 500
VAL A 141
THR A 144
 None
FAD  A 773 (-4.4A)
None
None
 1.32A 4lnxA-3redA:
undetectable		 4lnxA-3redA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tef IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-COMPOUND-BINDIN
G PROTEIN

(Vibrio cholerae) 		PF01497
(Peripla_BP_2) 		4 GLU A 157
GLN A 169
VAL A 133
THR A 151
 None
 1.30A 4lnxA-3tefA:
undetectable		 4lnxA-3tefA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3whj PROBABLE 26S
PROTEASOME
REGULATORY SUBUNIT
P27

(Saccharomyces
cerevisiae) 		no annotation 4 SER A  61
VAL A  79
THR A  80
ARG A  83
 None
 1.29A 4lnxA-3whjA:
undetectable		 4lnxA-3whjA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a35 MITOCHONDRIAL
ENOLASE SUPERFAMILY
MEMBER 1

(Homo sapiens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 SER A  14
GLU A  46
VAL A 427
ARG A  16
 None
 1.26A 4lnxA-4a35A:
undetectable		 4lnxA-4a35A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1

(Toxoplasma
gondii) 		PF01150
(GDA1_CD39) 		4 SER A 282
GLU A 277
GLN A 284
ARG A 192
 ANP  A 700 (-3.6A)
MG  A 701 (-4.7A)
None
None
 1.12A 4lnxA-4a5aA:
undetectable		 4lnxA-4a5aA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayg GLUCANSUCRASE

(Lactobacillus
reuteri) 		PF01473
(CW_binding_1)
PF02324
(Glyco_hydro_70) 		4 SER A1293
GLU A1292
VAL A1279
THR A1252
 GOL  A2776 (-2.8A)
GOL  A2776 ( 4.7A)
None
None
 1.35A 4lnxA-4aygA:
undetectable		 4lnxA-4aygA:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chg ANTITOXIN VAPB15
PROBABLE
RIBONUCLEASE VAPC15

(Mycobacterium
tuberculosis) 		PF01850
(PIN)
PF09957
(VapB_antitoxin) 		4 SER A   6
GLU G  67
VAL A 110
THR A 128
 None
MN  A1133 ( 1.9A)
None
None
 0.96A 4lnxA-4chgA:
undetectable		 4lnxA-4chgA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 SER A 528
GLU A 527
VAL A 484
THR A 289
 None
 1.28A 4lnxA-4ddwA:
undetectable		 4lnxA-4ddwA:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6w CLBP PEPTIDASE

(Escherichia
coli) 		PF00144
(Beta-lactamase) 		4 SER A 313
GLN A 106
VAL A 140
THR A 139
 None
 1.39A 4lnxA-4e6wA:
undetectable		 4lnxA-4e6wA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8e GLUTATHIONE
S-TRANSFERASE

(Bombyx mori) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 SER A  70
GLN A  74
VAL A 166
THR A 167
 None
 1.07A 4lnxA-4e8eA:
undetectable		 4lnxA-4e8eA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdy SIMILAR TO
LIPOPROTEIN, NLP/P60
FAMILY

(Staphylococcus
aureus) 		PF00877
(NLPC_P60)
PF13702
(Lysozyme_like) 		4 SER A 247
GLN A 268
VAL A 298
THR A 296
 OCS  A 246 ( 3.5A)
None
None
None
 1.25A 4lnxA-4fdyA:
undetectable		 4lnxA-4fdyA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgv CHROMOSOME REGION
MAINTENANCE 1 (CRM1)
OR EXPORTIN 1 (XPO1)

(Chaetomium
thermophilum) 		PF03810
(IBN_N)
PF08389
(Xpo1)
PF08767
(CRM1_C) 		4 GLU A 303
GLN A 246
THR A 208
ARG A 211
 None
 1.07A 4lnxA-4fgvA:
undetectable		 4lnxA-4fgvA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4frx ANAEROBICALLY-INDUCE
D OUTER MEMBRANE
PORIN OPRE

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 SER A 160
GLU A 138
VAL A 125
THR A 126
 None
 1.11A 4lnxA-4frxA:
undetectable		 4lnxA-4frxA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g54 GENERAL SECRETION
PATHWAY PROTEIN

(Vibrio
vulnificus) 		PF01471
(PG_binding_1) 		4 GLN A 539
VAL A 428
THR A 437
ARG A 426
 None
 1.17A 4lnxA-4g54A:
undetectable		 4lnxA-4g54A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i5n SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
REGULATORY SUBUNIT
B'' SUBUNIT BETA -
CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG CHIMERIC
CONSTRUCT

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 SER B 383
GLU B 384
VAL B 360
THR B 361
 None
 1.26A 4lnxA-4i5nB:
undetectable		 4lnxA-4i5nB:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k5y CORTICOTROPIN-RELEAS
ING FACTOR RECEPTOR
1, T4-LYSOZYME
CHIMERIC CONSTRUCT

(Escherichia
virus T4;
Homo sapiens) 		PF00002
(7tm_2)
PF00959
(Phage_lysozyme) 		4 SER A 304
GLU A 305
GLN A 308
THR A1157
 None
 1.39A 4lnxA-4k5yA:
undetectable		 4lnxA-4k5yA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ktp GLYCOSIDE HYDROLASE
FAMILY 65 CENTRAL
CATALYTIC

([Bacillus]
selenitireducens) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 GLU A 640
VAL A 724
THR A 725
ARG A 761
 None
 1.11A 4lnxA-4ktpA:
undetectable		 4lnxA-4ktpA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0q LEU/ILE/VAL-BINDING
PROTEIN HOMOLOG 3

(Brucella
melitensis) 		PF13458
(Peripla_BP_6) 		4 GLU A 295
GLN A  43
VAL A  99
THR A 100
 None
None
None
LEU  A 500 (-4.6A)
 1.29A 4lnxA-4n0qA:
undetectable		 4lnxA-4n0qA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0q LEU/ILE/VAL-BINDING
PROTEIN HOMOLOG 3

(Brucella
melitensis) 		PF13458
(Peripla_BP_6) 		4 SER A 205
GLN A 234
VAL A 197
THR A 198
 None
 1.18A 4lnxA-4n0qA:
undetectable		 4lnxA-4n0qA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ngu TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Desulfovibrio
alaskensis) 		PF03480
(DctP) 		4 SER A  65
GLN A 262
VAL A  35
THR A  34
 None
 1.26A 4lnxA-4nguA:
undetectable		 4lnxA-4nguA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ofy PROTEIN SYG-2

(Caenorhabditis
elegans) 		PF08205
(C2-set_2)
PF13927
(Ig_3) 		4 GLU D 215
GLN D 213
VAL D 154
THR D 189
 None
 1.39A 4lnxA-4ofyD:
undetectable		 4lnxA-4ofyD:
20.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4s15 NUCLEAR RECEPTOR
ROR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 GLU A 443
GLN A 446
VAL A 474
ARG A 478
 None
 1.01A 4lnxA-4s15A:
26.8		 4lnxA-4s15A:
32.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tzo C. ELEGANS HIM-3
CLOSURE MOTIF
PROTEIN HTP-1

(Caenorhabditis
elegans) 		PF02301
(HORMA)
no annotation 		4 SER B 282
GLU A 215
GLN B 283
THR B 286
 None
 1.20A 4lnxA-4tzoB:
undetectable		 4lnxA-4tzoB:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uiq GLOBIN-COUPLED
SENSOR WITH
DIGUANYLATE CYCLASE
ACTIVITY

(Bordetella
pertussis) 		PF11563
(Protoglobin) 		4 SER A  75
GLU A  74
VAL A 145
THR A 146
 None
 1.18A 4lnxA-4uiqA:
undetectable		 4lnxA-4uiqA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upl SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 SER A 498
GLN A 499
THR A  58
ARG A  60
 None
 1.38A 4lnxA-4uplA:
undetectable		 4lnxA-4uplA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w91 AMINOTRANSFERASE

(Brucella suis) 		PF00266
(Aminotran_5) 		4 SER A  80
GLU A  78
VAL A 243
THR A  99
 None
 1.36A 4lnxA-4w91A:
undetectable		 4lnxA-4w91A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyi KINETOCHORE PROTEIN
MIS16

(Schizosaccharomyces
japonicus) 		PF00400
(WD40)
PF12265
(CAF1C_H4-bd) 		4 SER A 298
GLU A 324
VAL A 251
THR A 256
 None
 1.21A 4lnxA-4xyiA:
undetectable		 4lnxA-4xyiA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynv ACL4

(Chaetomium
thermophilum) 		PF13432
(TPR_16) 		4 GLU A 212
GLN A 215
VAL A 276
THR A 277
 None
 1.28A 4lnxA-4ynvA:
undetectable		 4lnxA-4ynvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zuz SIDC

(Legionella
pneumophila) 		no annotation 4 SER A 154
GLU A 156
THR A 476
ARG A 477
 None
 1.09A 4lnxA-4zuzA:
undetectable		 4lnxA-4zuzA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5az3 ABC-TYPE
TRANSPORTER,
PERIPLASMIC
COMPONENT

(Corynebacterium
glutamicum) 		PF01497
(Peripla_BP_2) 		4 GLU A 299
VAL A 135
THR A 122
ARG A 121
 HEM  A 401 (-3.5A)
None
None
None
 1.30A 4lnxA-5az3A:
undetectable		 4lnxA-5az3A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5b DCC-INTERACTING
PROTEIN 13-BETA

(Homo sapiens) 		PF00169
(PH)
PF16746
(BAR_3) 		4 SER B 137
GLN B 174
THR B  19
ARG B  20
 None
 1.32A 4lnxA-5c5bB:
undetectable		 4lnxA-5c5bB:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cg0 BETA-GLUCOSIDASE

(Spodoptera
frugiperda) 		PF00232
(Glyco_hydro_1) 		4 SER A  77
VAL A 465
THR A 473
ARG A 474
 None
 1.35A 4lnxA-5cg0A:
undetectable		 4lnxA-5cg0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czw MYROILYSIN

(Myroides
profundi) 		PF01400
(Astacin) 		4 GLU A 153
GLN A 198
VAL A 240
THR A 239
 None
None
MLY  A  47 ( 4.7A)
None
 1.30A 4lnxA-5czwA:
undetectable		 4lnxA-5czwA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e2c XAA-PRO DIPEPTIDASE

(Mycobacterium
tuberculosis) 		PF01321
(Creatinase_N) 		4 SER A 125
GLU A 129
VAL A 102
THR A 103
 None
 1.38A 4lnxA-5e2cA:
undetectable		 4lnxA-5e2cA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO

(Photobacterium
angustum) 		PF00072
(Response_reg)
PF00158
(Sigma54_activat) 		4 SER A 187
VAL A 166
THR A 165
ARG A 277
 None
 1.19A 4lnxA-5ep0A:
undetectable		 4lnxA-5ep0A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ep1 PUTATIVE REPRESSOR
PROTEIN LUXO

(Photobacterium
angustum) 		PF00158
(Sigma54_activat) 		4 SER A 187
VAL A 166
THR A 165
ARG A 277
 None
None
ACT  A 402 ( 4.9A)
None
 1.22A 4lnxA-5ep1A:
undetectable		 4lnxA-5ep1A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5o NUCLEOPROTEIN

(Marburg
marburgvirus) 		PF05505
(Ebola_NP) 		4 SER A 217
GLN A 220
VAL A 160
THR A 159
 None
 0.72A 4lnxA-5f5oA:
undetectable		 4lnxA-5f5oA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbb NUCLEASE S1

(Aspergillus
oryzae) 		PF02265
(S1-P1_nuclease) 		4 SER A 253
GLU A 178
VAL A 158
THR A 164
 None
 1.31A 4lnxA-5fbbA:
undetectable		 4lnxA-5fbbA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 GLU A 890
VAL A 592
THR A 591
ARG A 590
 None
 1.15A 4lnxA-5kf7A:
undetectable		 4lnxA-5kf7A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l8s AMINO ACYL PEPTIDASE

(Sporosarcina
psychrophila) 		PF00326
(Peptidase_S9) 		4 SER A 247
GLN A 249
VAL A 202
THR A 178
 None
 1.26A 4lnxA-5l8sA:
undetectable		 4lnxA-5l8sA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mq6 PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF07992
(Pyr_redox_2) 		4 GLU A  37
GLN A  41
THR A 301
ARG A 300
 None
None
NDP  A 701 (-3.5A)
NDP  A 701 (-3.9A)
 1.26A 4lnxA-5mq6A:
undetectable		 4lnxA-5mq6A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 4 SER A 729
GLU A 688
VAL A 558
THR A 557
 None
 0.97A 4lnxA-5nd1A:
undetectable		 4lnxA-5nd1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sy4 CHAPERONE YAJL

(Escherichia
coli) 		PF01965
(DJ-1_PfpI) 		4 SER A  13
GLU A  14
VAL A   7
THR A  34
 None
 1.34A 4lnxA-5sy4A:
undetectable		 4lnxA-5sy4A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6f LPXTG-MOTIF CELL
WALL ANCHOR DOMAIN
PROTEIN

(Mobiluncus
mulieris) 		no annotation 4 SER A 259
GLU A 264
VAL A 284
THR A 285
 None
 1.12A 4lnxA-5u6fA:
undetectable		 4lnxA-5u6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgr ATLASTIN-3

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		4 SER A 168
GLN A 206
VAL A 316
THR A 317
 None
 1.11A 4lnxA-5vgrA:
undetectable		 4lnxA-5vgrA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7p OXAC

(Penicillium
oxalicum) 		no annotation 4 SER A 354
GLU A 369
GLN A 358
VAL A 215
 None
 1.36A 4lnxA-5w7pA:
undetectable		 4lnxA-5w7pA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdu ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 4 GLU A 654
GLN A 650
VAL G  36
THR G  37
 None
 1.20A 4lnxA-5wduA:
undetectable		 4lnxA-5wduA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 4 SER A  61
VAL A  17
THR A  16
ARG A  58
 None
None
G  B  -8 ( 2.7A)
None
 1.19A 4lnxA-5wlhA:
undetectable		 4lnxA-5wlhA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wqg ISOMERASE TRT14

(Aspergillus
terreus) 		no annotation 4 SER A  53
GLU A  52
THR A  32
ARG A  31
 None
 1.35A 4lnxA-5wqgA:
undetectable		 4lnxA-5wqgA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6x MRNA CAPPING ENZYME
P5

(Rice dwarf
virus) 		no annotation 4 SER C  71
GLU C  67
VAL C  93
THR C  94
 None
 1.37A 4lnxA-5x6xC:
undetectable		 4lnxA-5x6xC:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsq NUCLEOPROTEIN

(Marburg
marburgvirus) 		PF05505
(Ebola_NP) 		4 SER A 201
GLN A 204
VAL A 144
THR A 143
 None
 0.67A 4lnxA-5xsqA:
undetectable		 4lnxA-5xsqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu0 MEMBRANE-FUSION
PROTEIN

(Streptococcus
pneumoniae) 		no annotation 4 SER A 201
GLN A  72
VAL A 207
THR A 206
 None
 1.30A 4lnxA-5xu0A:
undetectable		 4lnxA-5xu0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xym 50S RIBOSOMAL
PROTEIN L22

(Mycolicibacterium
smegmatis) 		PF00237
(Ribosomal_L22) 		4 SER S   9
GLU S  69
VAL S 112
THR S 111
 None
 1.27A 4lnxA-5xymS:
undetectable		 4lnxA-5xymS:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zov -

(-) 		no annotation 4 GLU A 391
GLN A 337
VAL A 239
THR A 236
 None
 0.98A 4lnxA-5zovA:
undetectable		 4lnxA-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zvs PUTATIVE CORE
PROTEIN NTPASE/VP5

(Aquareovirus C) 		no annotation 4 GLN 4 587
VAL 4 687
THR 4 688
ARG 4 516
 None
 1.14A 4lnxA-5zvs4:
undetectable		 4lnxA-5zvs4:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6amz 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-SUCCINYLTRANSFERAS
E

(Acinetobacter
baumannii) 		PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2) 		4 SER A 115
GLN A 117
VAL A 146
THR A 145
 None
 1.35A 4lnxA-6amzA:
undetectable		 4lnxA-6amzA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g43 PUTATIVE MAJOR
CAPSID PROTEIN

(Cafeteriavirus-dependent
mavirus) 		no annotation 4 SER A 391
GLN A 371
VAL A 453
THR A 454
 None
 1.36A 4lnxA-6g43A:
undetectable		 4lnxA-6g43A:
16.16