SIMILAR PATTERNS OF AMINO ACIDS FOR 4LBG_B_ADNB402_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b7g | PROTEIN(GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE) (Sulfolobussolfataricus) |
PF01113(DapB_N)PF02800(Gp_dh_C) | 5 | GLU O 307ILE O 105ALA O 128ALA O 314ILE O 134 | None | 1.08A | 4lbgB-1b7gO:6.7 | 4lbgB-1b7gO:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1coy | CHOLESTEROL OXIDASE (Brevibacteriumsterolicum) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | ALA A 237ILE A 244VAL A 112ALA A 24ALA A 27 | None | 1.04A | 4lbgB-1coyA:undetectable | 4lbgB-1coyA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cp2 | NITROGENASE IRONPROTEIN (Clostridiumpasteurianum) |
PF00142(Fer4_NifH) | 5 | ALA A 133ILE A 165ALA A 5ALA A 141ILE A 144 | None | 1.08A | 4lbgB-1cp2A:3.5 | 4lbgB-1cp2A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1efp | PROTEIN (ELECTRONTRANSFERFLAVOPROTEIN) (Paracoccusdenitrificans) |
PF00766(ETF_alpha)PF01012(ETF) | 5 | ALA A 70ILE B 170VAL B 159ALA B 176ALA B 142 | None | 1.09A | 4lbgB-1efpA:2.4 | 4lbgB-1efpA:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gnz | GSI-B4 ISOLECTIN (Griffoniasimplicifolia) |
PF00139(Lectin_legB) | 5 | THR A 227ALA A 218ILE A 216CYH A 36ILE A 230 | None | 1.06A | 4lbgB-1gnzA:undetectable | 4lbgB-1gnzA:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1huq | RAB5C (Mus musculus) |
PF00071(Ras) | 5 | GLU A 118ALA A 123ILE A 129VAL A 99ALA A 94 | None | 1.10A | 4lbgB-1huqA:3.2 | 4lbgB-1huqA:20.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iwp | GLYCEROL DEHYDRATASEALPHA SUBUNIT (Klebsiellapneumoniae) |
PF02286(Dehydratase_LU) | 5 | GLU A 436ALA A 440ALA A 186ALA A 156ILE A 420 | None | 1.06A | 4lbgB-1iwpA:undetectable | 4lbgB-1iwpA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ji0 | ABC TRANSPORTER (Thermotogamaritima) |
PF00005(ABC_tran) | 5 | ALA A 222VAL A 210ALA A 198ALA A 201ILE A 37 | None | 1.10A | 4lbgB-1ji0A:undetectable | 4lbgB-1ji0A:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jvb | NAD(H)-DEPENDENTALCOHOLDEHYDROGENASE (Sulfolobussolfataricus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 91ILE A 30VAL A 130ALA A 35ALA A 34 | None | 1.08A | 4lbgB-1jvbA:3.9 | 4lbgB-1jvbA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1krq | FERRITIN (Campylobacterjejuni) |
PF00210(Ferritin) | 5 | ALA A 39ILE A 137VAL A 138ALA A 154ILE A 141 | None | 1.10A | 4lbgB-1krqA:undetectable | 4lbgB-1krqA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lk5 | D-RIBOSE-5-PHOSPHATEISOMERASE (Pyrococcushorikoshii) |
PF06026(Rib_5-P_isom_A) | 5 | GLU A 196ILE A 148VAL A 203ALA A 182ILE A 138 | None | 1.07A | 4lbgB-1lk5A:3.3 | 4lbgB-1lk5A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oi1 | SCML2 PROTEIN (Homo sapiens) |
PF02820(MBT) | 6 | ALA A 47ILE A 194VAL A 202ALA A 180ALA A 192ILE A 204 | None | 1.37A | 4lbgB-1oi1A:undetectable | 4lbgB-1oi1A:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbg | PYRUVATE,ORTHOPHOSPHATE DIKINASE (Zea mays) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | THR A 551VAL A 618ALA A 543ALA A 541ILE A 560 | None | 1.05A | 4lbgB-1vbgA:undetectable | 4lbgB-1vbgA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1o | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Thermusthermophilus) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ALA A 127ILE A 135VAL A 267ALA A 257ALA A 258 | None | 1.02A | 4lbgB-1x1oA:undetectable | 4lbgB-1x1oA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zc6 | PROBABLEN-ACETYLGLUCOSAMINEKINASE (Chromobacteriumviolaceum) |
PF01869(BcrAD_BadFG) | 5 | ILE A 14VAL A 16ALA A 38ALA A 63ILE A 25 | None | 1.08A | 4lbgB-1zc6A:undetectable | 4lbgB-1zc6A:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2an2 | P332G A333S DOUBLEMUTANT OF NITRICOXIDE SYNTHASE FROMBACILLUS SUBTILIS (Bacillussubtilis) |
PF02898(NO_synthase) | 5 | ALA A 283ILE A 198VAL A 260ALA A 276ILE A 261 | None | 1.02A | 4lbgB-2an2A:undetectable | 4lbgB-2an2A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bgk | RHIZOMESECOISOLARICIRESINOLDEHYDROGENASE (Podophyllumpeltatum) |
PF13561(adh_short_C2) | 6 | GLU A 184ILE A 190VAL A 192ALA A 133ALA A 136ILE A 148 | None | 1.41A | 4lbgB-2bgkA:7.1 | 4lbgB-2bgkA:23.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cxh | PROBABLE BRIX-DOMAINRIBOSOMAL BIOGENESISPROTEIN (Aeropyrumpernix) |
no annotation | 5 | ALA A 137VAL A 167ALA A 157ALA A 123ILE A 159 | None | 1.01A | 4lbgB-2cxhA:undetectable | 4lbgB-2cxhA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7d | UVRABC SYSTEMPROTEIN B (Bacillussubtilis) |
PF00271(Helicase_C)PF02151(UVR)PF04851(ResIII)PF12344(UvrB) | 6 | THR A 557ALA A 563ILE A 538VAL A 549ALA A 522ILE A 519 | None | 1.35A | 4lbgB-2d7dA:undetectable | 4lbgB-2d7dA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eer | NAD-DEPENDENTALCOHOLDEHYDROGENASE (Sulfurisphaeratokodaii) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | ALA A 91ILE A 30VAL A 130ALA A 35ALA A 34 | None | 1.09A | 4lbgB-2eerA:3.8 | 4lbgB-2eerA:25.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f4l | ACETAMIDASE,PUTATIVE (Thermotogamaritima) |
PF03069(FmdA_AmdA) | 5 | GLU A 235ILE A 277ALA A 251ALA A 255ILE A 240 | None | 1.06A | 4lbgB-2f4lA:undetectable | 4lbgB-2f4lA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fhk | FORMYLMETHANOFURAN--TETRAHYDROMETHANOPTERINFORMYLTRANSFERASE (Methanopyruskandleri) |
PF01913(FTR)PF02741(FTR_C) | 5 | ILE A 75VAL A 73ALA A 103CYH A 96ILE A 25 | NoneNone K A 711 (-4.2A)NoneNone | 1.02A | 4lbgB-2fhkA:undetectable | 4lbgB-2fhkA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fyw | CONSERVEDHYPOTHETICAL PROTEIN (Streptococcuspneumoniae) |
PF01784(NIF3) | 5 | THR A 259ILE A 93VAL A 95ALA A 42ILE A 61 | None | 0.95A | 4lbgB-2fywA:undetectable | 4lbgB-2fywA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gp6 | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]SYNTHASE 2 (Mycobacteriumtuberculosis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 6 | ALA A 329ILE A 305VAL A 308ALA A 411ALA A 294ILE A 399 | None | 1.42A | 4lbgB-2gp6A:undetectable | 4lbgB-2gp6A:25.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iih | MOLYBDENUM COFACTORBIOSYNTHESIS PROTEINC (Thermusthermophilus) |
PF01967(MoaC) | 5 | ALA A 30ILE A 137ALA A 56CYH A 117ALA A 120 | None | 0.95A | 4lbgB-2iihA:undetectable | 4lbgB-2iihA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iv0 | ISOCITRATEDEHYDROGENASE (Archaeoglobusfulgidus) |
PF00180(Iso_dh) | 5 | ALA A 68ILE A 114VAL A 328ALA A 87ILE A 88 | None | 1.10A | 4lbgB-2iv0A:2.4 | 4lbgB-2iv0A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lbf | 60S ACIDIC RIBOSOMALPROTEIN P2 (Homo sapiens) |
PF00428(Ribosomal_60s) | 5 | ALA B 105ILE B 155VAL B 154ALA B 111ILE B 151 | None | 1.04A | 4lbgB-2lbfB:undetectable | 4lbgB-2lbfB:15.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q01 | URONATE ISOMERASE (Caulobactervibrioides) |
PF02614(UxaC) | 5 | GLU A 170VAL A 191ALA A 48ALA A 181ILE A 182 | None | 1.03A | 4lbgB-2q01A:2.2 | 4lbgB-2q01A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wv9 | FLAVIVIRIN PROTEASENS2B REGULATORYSUBUNIT, FLAVIVIRINPROTEASE NS3CATALYTIC SUBUNIT (Murray Valleyencephalitisvirus) |
PF00271(Helicase_C)PF00949(Peptidase_S7)PF01002(Flavi_NS2B)PF07652(Flavi_DEAD) | 5 | ALA A 56ILE A 58ALA A 36ALA A 27ILE A 25 | None | 1.05A | 4lbgB-2wv9A:undetectable | 4lbgB-2wv9A:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xec | PUTATIVE MALEATEISOMERASE (Nocardiafarcinica) |
no annotation | 5 | ILE A 191VAL A 203ALA A 218CYH A 194ALA A 217 | NoneNoneNoneTRS A 300 (-3.1A)None | 1.03A | 4lbgB-2xecA:undetectable | 4lbgB-2xecA:26.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yrf | METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE (Bacillussubtilis) |
PF01008(IF-2B) | 5 | ALA A 263ILE A 266VAL A 235ALA A 223ALA A 224 | None | 1.03A | 4lbgB-2yrfA:4.2 | 4lbgB-2yrfA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z0j | PUTATIVEUNCHARACTERIZEDPROTEIN TTHA1438 (Thermusthermophilus) |
PF04029(2-ph_phosp) | 5 | ALA A 159ILE A 138VAL A 22ALA A 121ALA A 125 | None | 1.00A | 4lbgB-2z0jA:undetectable | 4lbgB-2z0jA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z7e | NIFU-LIKE PROTEIN (Aquifexaeolicus) |
PF01592(NifU_N) | 5 | ALA A 85ILE A 53VAL A 56ALA A 118ILE A 44 | None | 0.92A | 4lbgB-2z7eA:undetectable | 4lbgB-2z7eA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbv | UNCHARACTERIZEDCONSERVED PROTEIN (Thermotogamaritima) |
PF01887(SAM_adeno_trans) | 5 | ALA A 18ILE A 31ALA A 136ALA A 137ILE A 2 | None | 1.09A | 4lbgB-2zbvA:2.7 | 4lbgB-2zbvA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b3l | KETOHEXOKINASE (Homo sapiens) |
PF00294(PfkB) | 6 | GLU A 227ALA A 244VAL A 250ALA A 256CYH A 282ALA A 285 | None | 0.70A | 4lbgB-3b3lA:27.8 | 4lbgB-3b3lA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bfj | 1,3-PROPANEDIOLOXIDOREDUCTASE (Klebsiellapneumoniae) |
PF00465(Fe-ADH) | 6 | ALA A 228ILE A 224VAL A 204ALA A 327ALA A 308ILE A 307 | None | 1.26A | 4lbgB-3bfjA:3.3 | 4lbgB-3bfjA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fed | GLUTAMATECARBOXYPEPTIDASE III (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 5 | THR A 468ALA A 572ILE A 388VAL A 384ALA A 525 | None | 1.08A | 4lbgB-3fedA:undetectable | 4lbgB-3fedA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fvw | PUTATIVENAD(P)H-DEPENDENTFMN REDUCTASE (Streptococcusmutans) |
PF03358(FMN_red) | 5 | ALA A 175ILE A 29VAL A 35ALA A 70ILE A 5 | None | 1.07A | 4lbgB-3fvwA:undetectable | 4lbgB-3fvwA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ALA A 98VAL A 94ALA A 58ALA A 85ILE A 89 | None | 1.06A | 4lbgB-3g1uA:4.8 | 4lbgB-3g1uA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbd | CLASS IV CHITINASECHIA4-PA2 (Picea abies) |
PF00182(Glyco_hydro_19) | 5 | GLU A 102ILE A 52VAL A 49CYH A 238ILE A 53 | None | 1.08A | 4lbgB-3hbdA:undetectable | 4lbgB-3hbdA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i10 | PUTATIVEGLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Bacteroidesthetaiotaomicron) |
PF03009(GDPD)PF16387(DUF4996) | 5 | GLU A 220ALA A 218ILE A 281VAL A 44ILE A 71 | PEG A 21 (-3.1A)NoneNoneNoneNone | 1.05A | 4lbgB-3i10A:2.1 | 4lbgB-3i10A:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iay | DNA POLYMERASE DELTACATALYTIC SUBUNIT (Saccharomycescerevisiae) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | ALA A 533ILE A 399VAL A 397ALA A 349ILE A 317 | None | 1.10A | 4lbgB-3iayA:undetectable | 4lbgB-3iayA:17.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ik4 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Herpetosiphonaurantiacus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 183ILE A 160VAL A 162ALA A 145ILE A 137 | None | 0.95A | 4lbgB-3ik4A:undetectable | 4lbgB-3ik4A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwr | CHITINASE (Oryza sativa) |
PF00182(Glyco_hydro_19) | 5 | THR A 247ALA A 241ALA A 218ALA A 215ILE A 219 | None | 1.11A | 4lbgB-3iwrA:undetectable | 4lbgB-3iwrA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3knz | PUTATIVE SUGARBINDING PROTEIN (Salmonellaenterica) |
PF01380(SIS) | 5 | ALA A 154ILE A 34VAL A 83ALA A 22ALA A 23 | None | 1.06A | 4lbgB-3knzA:2.9 | 4lbgB-3knzA:25.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l51 | STRUCTURALMAINTENANCE OFCHROMOSOMES PROTEIN2 (Mus musculus) |
PF06470(SMC_hinge) | 5 | GLU A 542ALA A 545ILE A 530VAL A 532ALA A 606 | None | 1.06A | 4lbgB-3l51A:undetectable | 4lbgB-3l51A:17.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lhx | KETODEOXYGLUCONOKINASE (Shigellaflexneri) |
PF00294(PfkB) | 5 | ALA A 321VAL A 329ALA A 335ALA A 364ILE A 368 | None | 0.54A | 4lbgB-3lhxA:30.4 | 4lbgB-3lhxA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwg | HP0420 HOMOLOGUE (Helicobacterfelis) |
no annotation | 5 | ILE A 126ALA A 96CYH A 66ALA A 67ILE A 108 | None | 1.09A | 4lbgB-3lwgA:undetectable | 4lbgB-3lwgA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 5 | THR A 264VAL A 291ALA A 297ALA A 326ILE A 330 | AP5 A 346 (-3.6A)AP5 A 346 ( 4.9A)AP5 A 346 (-3.4A)AP5 A 346 (-3.0A)AP5 A 346 (-4.9A) | 0.49A | 4lbgB-3otxA:39.6 | 4lbgB-3otxA:25.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p9t | REPRESSOR (Stenotrophomonasmaltophilia) |
PF00440(TetR_N)PF08361(TetR_C_2) | 5 | ALA A 39ILE A 37ALA A 11ALA A 47ILE A 16 | None | 1.08A | 4lbgB-3p9tA:undetectable | 4lbgB-3p9tA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p9x | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Bacillushalodurans) |
PF00551(Formyl_trans_N) | 5 | GLU A 16VAL A 31ALA A 8ALA A 87ILE A 6 | None | 1.06A | 4lbgB-3p9xA:4.6 | 4lbgB-3p9xA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qdf | 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATEISOMERASE (Mycobacteriummarinum) |
PF01557(FAA_hydrolase)PF10370(DUF2437) | 5 | THR A 43VAL A 52ALA A 15ALA A 13ILE A 6 | None | 1.10A | 4lbgB-3qdfA:undetectable | 4lbgB-3qdfA:26.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rqi | RESPONSE REGULATORPROTEIN (Burkholderiapseudomallei) |
PF00072(Response_reg)PF02954(HTH_8) | 5 | ALA A 43ILE A 51VAL A 53ALA A 33ILE A 9 | NoneNonePHD A 54 ( 3.1A)NoneNone | 1.01A | 4lbgB-3rqiA:5.4 | 4lbgB-3rqiA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7c | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | GLU A 187ILE A 193VAL A 195ALA A 136ILE A 152 | None | 1.05A | 4lbgB-3t7cA:6.4 | 4lbgB-3t7cA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr1 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Coxiellaburnetii) |
PF00275(EPSP_synthase) | 5 | THR A 397ALA A 422ILE A 15ALA A 244ILE A 252 | None | 1.03A | 4lbgB-3tr1A:undetectable | 4lbgB-3tr1A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9i | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,C-TERMINAL DOMAINPROTEIN (Roseiflexus sp.RS-1) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 190ILE A 166ALA A 152ALA A 153ILE A 141 | None | 0.99A | 4lbgB-3u9iA:undetectable | 4lbgB-3u9iA:27.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ubo | ADENOSINE KINASE (Sinorhizobiummeliloti) |
PF00294(PfkB) | 7 | THR A 245GLU A 248ALA A 264VAL A 270ALA A 276ALA A 305ILE A 309 | ADP A 354 (-3.3A)ADP A 354 (-4.9A)ADP A 354 ( 4.0A)NoneADP A 354 (-3.4A)ADP A 354 (-2.7A)None | 0.45A | 4lbgB-3uboA:57.0 | 4lbgB-3uboA:71.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vrk | CARBONYL SULFIDEHYDROLASE (Thiobacillusthioparus) |
PF00484(Pro_CA) | 6 | ALA A 76ILE A 178VAL A 194ALA A 40CYH A 79ILE A 92 | None | 1.18A | 4lbgB-3vrkA:undetectable | 4lbgB-3vrkA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9i | MULTIDRUG RESISTANCEPROTEIN MEXB (Pseudomonasaeruginosa) |
PF00873(ACR_tran) | 5 | ALA A 651VAL A 606ALA A 627ALA A 574ILE A 629 | None | 1.11A | 4lbgB-3w9iA:undetectable | 4lbgB-3w9iA:15.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zh4 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 5 | ALA A 175ILE A 184ALA A 132ALA A 156ILE A 158 | None | 0.99A | 4lbgB-3zh4A:undetectable | 4lbgB-3zh4A:24.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zhy | 1-DEOXY-D-XYLULOSE5-PHOSPHATEREDUCTOISOMERASE (Mycobacteriumtuberculosis) |
PF02670(DXP_reductoisom)PF08436(DXP_redisom_C)PF13288(DXPR_C) | 5 | ALA A 329ILE A 350VAL A 386ALA A 335ALA A 334 | None | 1.06A | 4lbgB-3zhyA:5.9 | 4lbgB-3zhyA:25.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b3i | FATTY ACIDBETA-OXIDATIONCOMPLEX BETA-CHAINFADA (Mycobacteriumtuberculosis) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ALA C 284VAL C 267ALA C 103ALA C 5ILE C 269 | None | 0.91A | 4lbgB-4b3iC:undetectable | 4lbgB-4b3iC:24.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmv | SHORT-CHAINDEHYDROGENASE (Sphingobiumyanoikuyae) |
PF00106(adh_short) | 5 | GLU A 170ILE A 176VAL A 178ALA A 120ILE A 135 | None | 1.03A | 4lbgB-4bmvA:6.7 | 4lbgB-4bmvA:22.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4e3a | SUGAR KINASE PROTEIN (Rhizobium etli) |
PF00294(PfkB) | 9 | THR A 243GLU A 246ALA A 262ILE A 265VAL A 268ALA A 274CYH A 300ALA A 303ILE A 307 | None | 0.42A | 4lbgB-4e3aA:62.6 | 4lbgB-4e3aA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e84 | D-BETA-D-HEPTOSE7-PHOSPHATE KINASE (Burkholderiacenocepacia) |
PF00294(PfkB) | 5 | THR A 238GLU A 241ALA A 257ALA A 268ALA A 297 | ANP A 501 (-3.8A)NoneANP A 501 ( 3.7A)ANP A 501 (-3.5A)ANP A 501 (-3.7A) | 0.53A | 4lbgB-4e84A:27.3 | 4lbgB-4e84A:28.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e84 | D-BETA-D-HEPTOSE7-PHOSPHATE KINASE (Burkholderiacenocepacia) |
PF00294(PfkB) | 5 | THR A 238GLU A 241VAL A 262ALA A 268ALA A 297 | ANP A 501 (-3.8A)NoneANP A 501 (-4.4A)ANP A 501 (-3.5A)ANP A 501 (-3.7A) | 0.64A | 4lbgB-4e84A:27.3 | 4lbgB-4e84A:28.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ej6 | PUTATIVEZINC-BINDINGDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 5 | THR A 206ILE A 235VAL A 152ALA A 184ILE A 157 | None | 1.05A | 4lbgB-4ej6A:3.9 | 4lbgB-4ej6A:28.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gic | HISTIDINOLDEHYDROGENASE (Methylococcuscapsulatus) |
PF00815(Histidinol_dh) | 5 | ALA A 273ILE A 6VAL A 4ALA A 258ILE A 290 | None | 1.04A | 4lbgB-4gicA:3.0 | 4lbgB-4gicA:24.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h14 | SPIKE GLYCOPROTEIN (Betacoronavirus1) |
PF16451(Spike_NTD) | 5 | THR A 230ALA A 105ILE A 125VAL A 140ALA A 221 | None | 1.06A | 4lbgB-4h14A:undetectable | 4lbgB-4h14A:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4itu | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Xanthobacterautotrophicus) |
PF13561(adh_short_C2) | 5 | ALA A 32ILE A 231VAL A 230ALA A 24ILE A 23 | None | 1.07A | 4lbgB-4ituA:3.9 | 4lbgB-4ituA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jn6 | ACETALDEHYDEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF01118(Semialdhyde_dh)PF09290(AcetDehyd-dimer) | 5 | ALA B 119ILE B 292VAL B 288ALA B 95ILE B 96 | None | 0.99A | 4lbgB-4jn6B:5.8 | 4lbgB-4jn6B:21.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4jwv | SHORT CHAINENOYL-COA HYDRATASE (Novosphingobiumaromaticivorans) |
PF00378(ECH_1) | 5 | VAL A 176ALA A 99CYH A 115ALA A 116ILE A 119 | None | 0.95A | 4lbgB-4jwvA:undetectable | 4lbgB-4jwvA:30.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ldz | TRANSCRIPTIONALREGULATORY PROTEINDESR (Bacillussubtilis) |
PF00072(Response_reg)PF00196(GerE) | 5 | GLU A 67ALA A 65ILE A 76VAL A 96ILE A 78 | None | 1.07A | 4lbgB-4ldzA:4.8 | 4lbgB-4ldzA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nxy | ACYL-COA SYNTHETASE (Streptomyceslividans) |
PF00583(Acetyltransf_1) | 5 | ALA A 122VAL A 103ALA A 146ALA A 149ILE A 145 | None | 1.10A | 4lbgB-4nxyA:undetectable | 4lbgB-4nxyA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o3s | DNA POLYMERASE ETA (Homo sapiens) |
PF00817(IMS)PF11799(IMS_C) | 5 | ALA A 54ALA A 65CYH A 72ALA A 68ILE A 47 | None | 0.99A | 4lbgB-4o3sA:undetectable | 4lbgB-4o3sA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oo0 | MAF-LIKE PROTEINBCAL2394 (Burkholderiacenocepacia) |
PF02545(Maf) | 5 | ILE A 189VAL A 150ALA A 182ALA A 183ILE A 186 | None | 1.04A | 4lbgB-4oo0A:undetectable | 4lbgB-4oo0A:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ou2 | 2-AMINOMUCONATE6-SEMIALDEHYDEDEHYDROGENASE (Pseudomonasfluorescens) |
PF00171(Aldedh) | 5 | ALA A 274ILE A 451VAL A 447ALA A 435ILE A 436 | None | 0.99A | 4lbgB-4ou2A:3.4 | 4lbgB-4ou2A:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfb | CT263 (Chlamydiatrachomatis) |
no annotation | 5 | THR A 17ALA A 185ILE A 109ALA A 70ILE A 68 | None | 0.96A | 4lbgB-4qfbA:undetectable | 4lbgB-4qfbA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r81 | NADH DEHYDROGENASE (Methanothermobactermarburgensis) |
PF02525(Flavodoxin_2) | 5 | ILE A 122VAL A 163ALA A 81ALA A 79ILE A 124 | None | 0.98A | 4lbgB-4r81A:undetectable | 4lbgB-4r81A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbn | SUCROSESYNTHASE:GLYCOSYLTRANSFERASES GROUP 1 (Nitrosomonaseuropaea) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 5 | ALA A 591ILE A 655VAL A 657ALA A 709ALA A 713 | None | 1.09A | 4lbgB-4rbnA:3.1 | 4lbgB-4rbnA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rsm | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Mycolicibacteriumsmegmatis) |
PF13407(Peripla_BP_4) | 5 | GLU A 341ALA A 339ALA A 276ALA A 277ILE A 329 | None | 1.10A | 4lbgB-4rsmA:4.1 | 4lbgB-4rsmA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ry9 | PERIPLASMIC BINDINGPROTEIN/LACITRANSCRIPTIONALREGULATOR (Verminephrobactereiseniae) |
PF13407(Peripla_BP_4) | 5 | ALA A 163ILE A 253ALA A 244ALA A 241ILE A 245 | None | 1.01A | 4lbgB-4ry9A:6.0 | 4lbgB-4ry9A:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w8i | PROBABLESPHINGOSINE-1-PHOSPHATE LYASE (Legionellapneumophila) |
PF00282(Pyridoxal_deC) | 5 | ALA A 258ILE A 245VAL A 293ALA A 230ALA A 229 | None | 1.10A | 4lbgB-4w8iA:3.5 | 4lbgB-4w8iA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wji | PUTATIVECYCLOHEXADIENYLDEHYDROGENASE ANDADH PREPHENATEDEHYDROGENASE (Sinorhizobiummeliloti) |
PF02153(PDH) | 5 | ALA A 66VAL A 71ALA A 59ALA A 62ILE A 11 | None | 1.07A | 4lbgB-4wjiA:4.2 | 4lbgB-4wjiA:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wut | ABC TRANSPORTERSUBSTRATE BINDINGPROTEIN (RIBOSE) (Agrobacteriumvitis) |
PF13407(Peripla_BP_4) | 5 | ALA A 99ILE A 86VAL A 83ALA A 106ILE A 108 | None | 1.09A | 4lbgB-4wutA:5.5 | 4lbgB-4wutA:28.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8r | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Rhodobactersphaeroides) |
PF03480(DctP) | 5 | GLU A 207ILE A 203VAL A 194ALA A 222ILE A 198 | None | 0.91A | 4lbgB-4x8rA:undetectable | 4lbgB-4x8rA:26.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3k | PUTATIVEPTERIDINE-DEPENDENTDIOXYGENASE (Streptomyceshygroscopicus) |
no annotation | 5 | ALA A 312ILE A 292VAL A 294ALA A 262ILE A 335 | None | 0.90A | 4lbgB-5a3kA:undetectable | 4lbgB-5a3kA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bp8 | ENT-COPALYLDIPHOSPHATE SYNTHASE (Streptomycesplatensis) |
PF00432(Prenyltrans)PF13243(SQHop_cyclase_C) | 5 | ALA A 417ILE A 385ALA A 316ALA A 363ILE A 360 | None | 1.00A | 4lbgB-5bp8A:undetectable | 4lbgB-5bp8A:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqp | EDTA MONOOXYGENASE (EDTA-degradingbacterium BNC1) |
PF00296(Bac_luciferase) | 5 | GLU A 246ALA A 250VAL A 263ALA A 223ILE A 230 | None | 0.97A | 4lbgB-5dqpA:undetectable | 4lbgB-5dqpA:24.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnd | PUTATIVE SERINEPROTEASE HHOA (Synechocystissp. PCC 6803) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ALA A 265ILE A 249VAL A 248ALA A 271ILE A 268 | None | 1.06A | 4lbgB-5gndA:undetectable | 4lbgB-5gndA:22.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5hsg | PUTATIVE ABCTRANSPORTER,NUCLEOTIDEBINDING/ATPASEPROTEIN (Klebsiellapneumoniae) |
PF13407(Peripla_BP_4) | 5 | GLU A 237ILE A 245VAL A 247ALA A 208ILE A 221 | None | 1.10A | 4lbgB-5hsgA:4.6 | 4lbgB-5hsgA:30.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huo | NICOTINATE-NUCLEOTIDE DIPHOSPHORYLASE(CARBOXYLATING) (Streptococcuspyogenes) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | ALA A 233ILE A 243ALA A 212ALA A 213ILE A 220 | None | 1.08A | 4lbgB-5huoA:undetectable | 4lbgB-5huoA:29.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5im5 | DESIGNEDKETO-HYDROXYGLUTARATE-ALDOLASE/KETO-DEOXY-PHOSPHOGLUCONATEALDOLASE (VibrionalesbacteriumSWAT-3) |
no annotation | 5 | THR P 69ALA P 49ILE P 25ALA P 18ILE P 17 | None | 1.10A | 4lbgB-5im5P:undetectable | 4lbgB-5im5P:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5int | PHOSPHOPANTOTHENOYLCYSTEINEDECARBOXYLASE (Bacillusanthracis) |
PF04127(DFP) | 5 | ILE A 271VAL A 269ALA A 228ALA A 223ILE A 190 | None | 1.04A | 4lbgB-5intA:5.2 | 4lbgB-5intA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l16 | PUTATIVESELENOPHOSPHATESYNTHETASE (Leishmaniamajor) |
PF00586(AIRS)PF02769(AIRS_C) | 5 | ALA A 151ILE A 178ALA A 251ALA A 252ILE A 173 | None | 1.10A | 4lbgB-5l16A:undetectable | 4lbgB-5l16A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5unl | 3-KETOACYL-ACPREDUCTASE (Burkholderiamultivorans) |
PF13561(adh_short_C2) | 5 | GLU A 178ILE A 184VAL A 186ALA A 130ILE A 143 | None | 1.06A | 4lbgB-5unlA:5.9 | 4lbgB-5unlA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wi5 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE 1 (Streptococcuspneumoniae) |
PF00275(EPSP_synthase) | 5 | ALA A 177ILE A 186ALA A 136ALA A 158ILE A 160 | None | 0.96A | 4lbgB-5wi5A:undetectable | 4lbgB-5wi5A:24.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydp | TETR TRANSCRIPTIONALREGULATORY PROTEIN (Dietzia sp.DQ12-45-1b) |
PF00440(TetR_N) | 5 | ALA A 159ILE A 93ALA A 175ALA A 176ILE A 179 | None | 0.94A | 4lbgB-5ydpA:undetectable | 4lbgB-5ydpA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cn1 | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Pseudomonasputida) |
no annotation | 5 | ALA A 346ILE A 319VAL A 247ALA A 383ALA A 386 | None | 1.07A | 4lbgB-6cn1A:undetectable | 4lbgB-6cn1A:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | POLYSULPHIDEREDUCTASE NRFD (Rhodothermusmarinus) |
no annotation | 5 | ALA C 290ILE C 300ALA C 121ALA C 120ILE C 117 | None | 1.03A | 4lbgB-6f0kC:undetectable | 4lbgB-6f0kC:14.38 |