SIMILAR PATTERNS OF AMINO ACIDS FOR 4LB0_B_ACTB401_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b3b PROTEIN (GLUTAMATE
DEHYDROGENASE)

(Thermotoga
maritima) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 VAL A 107
LEU A 122
VAL A  43
PHE A  41
 None
 1.05A 4lb0B-1b3bA:
0.0		 4lb0B-1b3bA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d3y DNA TOPOISOMERASE VI
A SUBUNIT

(Methanocaldococcus
jannaschii) 		PF04406
(TP6A_N) 		4 VAL A 286
LEU A 344
VAL A 352
PHE A 247
 None
 1.01A 4lb0B-1d3yA:
undetectable		 4lb0B-1d3yA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5f E6AP HECT CATALYTIC
DOMAIN, E3 LIGASE

(Homo sapiens) 		PF00632
(HECT) 		4 GLU A 558
VAL A 555
VAL A 504
PHE A 551
 None
 0.92A 4lb0B-1d5fA:
0.0		 4lb0B-1d5fA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ebl BETA-KETOACYL-ACP
SYNTHASE III

(Escherichia
coli) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 VAL A 315
LEU A 284
VAL A 288
PHE A 317
 None
 0.91A 4lb0B-1eblA:
0.0		 4lb0B-1eblA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f9k ACIDIC LECTIN

(Psophocarpus
tetragonolobus) 		PF00139
(Lectin_legB) 		4 VAL A 122
LEU A 174
VAL A 193
PHE A 120
 None
 1.02A 4lb0B-1f9kA:
0.0		 4lb0B-1f9kA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fgg GLUCURONYLTRANSFERAS
E I

(Homo sapiens) 		PF03360
(Glyco_transf_43) 		4 VAL A 251
LEU A 294
VAL A 236
PHE A 239
 None
 0.94A 4lb0B-1fggA:
0.1		 4lb0B-1fggA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fhu O-SUCCINYLBENZOATE
SYNTHASE

(Escherichia
coli) 		PF13378
(MR_MLE_C) 		4 VAL A 178
LEU A 160
VAL A 134
PHE A 174
 None
 1.06A 4lb0B-1fhuA:
0.0		 4lb0B-1fhuA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gpp ENDONUCLEASE PI-SCEI

(Saccharomyces
cerevisiae) 		PF05203
(Hom_end_hint) 		4 VAL A  50
LEU A  81
VAL A  83
PHE A 421
 None
 1.00A 4lb0B-1gppA:
0.0		 4lb0B-1gppA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 VAL S 609
LEU S 362
VAL S 387
PHE S 398
 None
 0.99A 4lb0B-1i84S:
0.0		 4lb0B-1i84S:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ipk BETA-CONGLYCININ,
BETA CHAIN

(Glycine max) 		PF00190
(Cupin_1)
PF07883
(Cupin_2) 		4 VAL A 327
LEU A 274
VAL A 272
PHE A 325
 None
 0.98A 4lb0B-1ipkA:
undetectable		 4lb0B-1ipkA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lc0 BILIVERDIN REDUCTASE
A

(Rattus
norvegicus) 		PF01408
(GFO_IDH_MocA)
PF09166
(Biliv-reduc_cat) 		4 VAL A 228
LEU A 135
VAL A 139
PHE A 230
 None
 0.73A 4lb0B-1lc0A:
undetectable		 4lb0B-1lc0A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhy METHANE
MONOOXYGENASE
HYDROXYLASE

(Methylosinus
trichosporium) 		PF02332
(Phenol_Hydrox) 		4 VAL B 364
LEU B 335
VAL B 389
PHE B 365
 None
 0.99A 4lb0B-1mhyB:
undetectable		 4lb0B-1mhyB:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mjf SPERMIDINE SYNTHASE

(Pyrococcus
furiosus) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 GLU A   6
VAL A  14
VAL A  53
PHE A  16
 None
 1.01A 4lb0B-1mjfA:
undetectable		 4lb0B-1mjfA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ne7 GLUCOSAMINE-6-PHOSPH
ATE ISOMERASE

(Homo sapiens) 		PF01182
(Glucosamine_iso) 		4 GLU A 198
VAL A 236
LEU A 265
VAL A 266
 None
 1.04A 4lb0B-1ne7A:
undetectable		 4lb0B-1ne7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oow PLASTOCYANIN,
CHLOROPLAST

(Spinacia
oleracea) 		PF00127
(Copper-bind) 		4 GLU A  25
VAL A  21
VAL A   3
PHE A  19
 None
 1.05A 4lb0B-1oowA:
undetectable		 4lb0B-1oowA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1opc OMPR

(Escherichia
coli) 		PF00486
(Trans_reg_C) 		4 VAL A 212
LEU A 169
VAL A 173
PHE A 140
 None
 0.91A 4lb0B-1opcA:
undetectable		 4lb0B-1opcA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozh ACETOLACTATE
SYNTHASE, CATABOLIC

(Klebsiella
pneumoniae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 148
LEU A  21
VAL A  26
PHE A 152
 None
 1.04A 4lb0B-1ozhA:
undetectable		 4lb0B-1ozhA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qho ALPHA-AMYLASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG)
PF02806
(Alpha-amylase_C) 		4 VAL A 114
LEU A  71
VAL A  74
PHE A 110
 None
 0.99A 4lb0B-1qhoA:
undetectable		 4lb0B-1qhoA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s6r BETA-LACTAMASE

(Enterobacter
cloacae) 		PF00144
(Beta-lactamase) 		4 VAL A 223
LEU A 179
VAL A 178
PHE A  69
 None
 1.05A 4lb0B-1s6rA:
undetectable		 4lb0B-1s6rA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sf8 CHAPERONE PROTEIN
HTPG

(Escherichia
coli) 		PF00183
(HSP90) 		5 GLU A 594
VAL A 593
LEU A 519
VAL A 523
PHE A 568
 None
 1.37A 4lb0B-1sf8A:
undetectable		 4lb0B-1sf8A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3h DEPHOSPHO-COA KINASE

(Escherichia
coli) 		PF01121
(CoaE) 		4 VAL A  18
LEU A 128
VAL A   5
PHE A  22
 None
 1.01A 4lb0B-1t3hA:
undetectable		 4lb0B-1t3hA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ACTIN-RELATED
PROTEIN 2

(Bos taurus) 		PF00022
(Actin) 		4 VAL B 278
LEU B 313
VAL B 223
PHE B 266
 None
 0.77A 4lb0B-1u2vB:
undetectable		 4lb0B-1u2vB:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1um2 ENDONUCLEASE PI-SCEI

(Saccharomyces
cerevisiae) 		PF05203
(Hom_end_hint)
PF05204
(Hom_end) 		4 VAL A 333
LEU A 364
VAL A 366
PHE A 704
 None
 1.05A 4lb0B-1um2A:
undetectable		 4lb0B-1um2A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfi UNKNOWN PROTEIN

(Arabidopsis
thaliana) 		PF01937
(DUF89) 		4 VAL A 317
LEU A 298
VAL A 301
PHE A 218
 None
 1.03A 4lb0B-1xfiA:
undetectable		 4lb0B-1xfiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zx5 MANNOSEPHOSPHATE
ISOMERASE, PUTATIVE

(Archaeoglobus
fulgidus) 		PF01238
(PMI_typeI) 		4 VAL A 285
LEU A 251
VAL A 276
PHE A 283
 None
 1.00A 4lb0B-1zx5A:
undetectable		 4lb0B-1zx5A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bwm PSATHYRELLA VELUTINA
LECTIN PVL

(Lacrymaria
velutina) 		PF13517
(VCBS) 		4 VAL A 267
LEU A 243
VAL A 286
PHE A 316
 None
 0.94A 4lb0B-2bwmA:
undetectable		 4lb0B-2bwmA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cr5 REPRODUCTION 8

(Mus musculus) 		PF00789
(UBX) 		4 VAL A  26
LEU A  49
VAL A  48
PHE A  40
 None
 1.05A 4lb0B-2cr5A:
undetectable		 4lb0B-2cr5A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cru PROGRAMMED CELL
DEATH PROTEIN 5

(Homo sapiens) 		PF01984
(dsDNA_bind) 		4 GLU A  70
VAL A  69
LEU A  91
VAL A  86
 None
 0.99A 4lb0B-2cruA:
undetectable		 4lb0B-2cruA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3n ALPHA-GLUCOSIDASE

(Sulfolobus
solfataricus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 VAL A 149
LEU A  43
VAL A  54
PHE A 147
 None
 0.95A 4lb0B-2g3nA:
undetectable		 4lb0B-2g3nA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hxv DIAMINOHYDROXYPHOSPH
ORIBOSYLAMINOPYRIMID
INE DEAMINASE/
5-AMINO-6-(5-PHOSPHO
RIBOSYLAMINO)URACIL
REDUCTASE

(Thermotoga
maritima) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		4 VAL A 286
LEU A 191
VAL A 278
PHE A 290
 NDP  A 400 (-4.0A)
None
None
None
 1.00A 4lb0B-2hxvA:
undetectable		 4lb0B-2hxvA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox)
PF04945
(YHS) 		4 VAL A 118
LEU A 191
VAL A 243
PHE A 122
 None
 1.00A 4lb0B-2inpA:
undetectable		 4lb0B-2inpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k47 PHOSPHOPROTEIN

(Indiana
vesiculovirus) 		PF00922
(Phosphoprotein) 		4 VAL A   3
LEU A  54
VAL A  40
PHE A  37
 None
 1.04A 4lb0B-2k47A:
undetectable		 4lb0B-2k47A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mdr DOUBLE-STRANDED
RNA-SPECIFIC
ADENOSINE DEAMINASE

(Homo sapiens) 		PF00035
(dsrm) 		4 VAL A 764
LEU A 792
VAL A 791
PHE A 769
 None
 1.04A 4lb0B-2mdrA:
undetectable		 4lb0B-2mdrA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pas PARVALBUMIN

(Esox lucius) 		PF13499
(EF-hand_7) 		4 VAL A  18
LEU A  67
VAL A  66
PHE A  24
 None
 1.02A 4lb0B-2pasA:
undetectable		 4lb0B-2pasA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xtl CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF16569
(GramPos_pilinBB)
PF16570
(GramPos_pilinD3) 		4 VAL A 479
LEU A 580
VAL A 607
PHE A 605
 None
 1.05A 4lb0B-2xtlA:
undetectable		 4lb0B-2xtlA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z23 PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Yersinia pestis) 		PF00496
(SBP_bac_5) 		4 VAL A 146
LEU A 159
VAL A  48
PHE A  74
 None
 0.74A 4lb0B-2z23A:
undetectable		 4lb0B-2z23A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsu SPERMIDINE SYNTHASE

(Pyrococcus
horikoshii) 		PF01564
(Spermine_synth)
PF17284
(Spermine_synt_N) 		4 GLU A   8
VAL A  16
VAL A  55
PHE A  18
 AG3  A1001 (-3.2A)
None
None
None
 0.95A 4lb0B-2zsuA:
undetectable		 4lb0B-2zsuA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3abz BETA-GLUCOSIDASE I

(Kluyveromyces
marxianus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF07691
(PA14)
PF14310
(Fn3-like) 		4 VAL A 442
LEU A 463
VAL A 531
PHE A 550
 GOL  A5002 ( 3.8A)
None
None
None
 1.05A 4lb0B-3abzA:
undetectable		 4lb0B-3abzA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8f PYRUVATE
FORMATE-LYASE
1-ACTIVATING ENZYME

(Escherichia
coli) 		PF04055
(Radical_SAM)
PF13353
(Fer4_12) 		4 GLU A  79
LEU A 103
VAL A 126
PHE A 152
 None
 0.89A 4lb0B-3c8fA:
undetectable		 4lb0B-3c8fA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3es6 PROLACTIN-INDUCIBLE
PROTEIN

(Homo sapiens) 		PF05326
(SVA) 		4 VAL B  24
LEU B 115
VAL B  80
PHE B  74
 None
 1.02A 4lb0B-3es6B:
undetectable		 4lb0B-3es6B:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f41 PHYTASE

(Mitsuokella
multacida) 		PF14566
(PTPlike_phytase) 		4 VAL A 319
LEU A 234
VAL A 230
PHE A 315
 None
 1.04A 4lb0B-3f41A:
undetectable		 4lb0B-3f41A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gc2 O-SUCCINYLBENZOATE
SYNTHASE

(Salmonella
enterica) 		PF13378
(MR_MLE_C) 		4 VAL A 178
LEU A 160
VAL A 134
PHE A 174
 None
 0.97A 4lb0B-3gc2A:
undetectable		 4lb0B-3gc2A:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7n NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae) 		PF11715
(Nup160) 		4 VAL A 175
LEU A 234
VAL A 236
PHE A 177
 None
 1.01A 4lb0B-3h7nA:
undetectable		 4lb0B-3h7nA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ief TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE

(Bartonella
henselae) 		PF01746
(tRNA_m1G_MT) 		4 GLU A 127
VAL A 129
LEU A 100
VAL A 106
 None
 1.01A 4lb0B-3iefA:
undetectable		 4lb0B-3iefA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jvd TRANSCRIPTIONAL
REGULATORS

(Corynebacterium
glutamicum) 		PF13377
(Peripla_BP_3) 		4 VAL A 246
LEU A 235
VAL A 261
PHE A 250
 None
 1.03A 4lb0B-3jvdA:
undetectable		 4lb0B-3jvdA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8k ALPHA-AMYLASE, SUSG

(Bacteroides
thetaiotaomicron) 		PF00128
(Alpha-amylase) 		4 VAL A 218
LEU A 222
VAL A 238
PHE A 333
 None
 0.99A 4lb0B-3k8kA:
undetectable		 4lb0B-3k8kA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kws PUTATIVE SUGAR
ISOMERASE

(Parabacteroides
distasonis) 		PF01261
(AP_endonuc_2) 		4 VAL A 250
LEU A  53
VAL A  77
PHE A 286
 None
 1.05A 4lb0B-3kwsA:
undetectable		 4lb0B-3kwsA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mqg LIPOPOLYSACCHARIDES
BIOSYNTHESIS
ACETYLTRANSFERASE

(Bordetella
petrii) 		PF00132
(Hexapep) 		4 VAL A  64
LEU A  70
VAL A 103
PHE A  82
 None
 0.91A 4lb0B-3mqgA:
undetectable		 4lb0B-3mqgA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oyz MALATE SYNTHASE

(Haloferax
volcanii) 		PF03328
(HpcH_HpaI) 		4 VAL A  45
LEU A 185
VAL A 187
PHE A  14
 None
 1.02A 4lb0B-3oyzA:
undetectable		 4lb0B-3oyzA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s0m OXALATE
DECARBOXYLASE OXDC

(Bacillus
subtilis) 		PF00190
(Cupin_1) 		4 GLU A  67
VAL A  82
VAL A 165
PHE A 155
 None
None
None
CO3  A 600 (-4.6A)
 1.02A 4lb0B-3s0mA:
undetectable		 4lb0B-3s0mA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txa CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF00092
(VWA) 		4 VAL A 584
LEU A 222
VAL A 224
PHE A 580
 None
 0.82A 4lb0B-3txaA:
undetectable		 4lb0B-3txaA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upn PENICILLIN-BINDING
PROTEIN A

(Mycobacterium
tuberculosis) 		PF00905
(Transpeptidase) 		4 VAL A 391
LEU A 399
VAL A 226
PHE A 305
 None
 0.99A 4lb0B-3upnA:
undetectable		 4lb0B-3upnA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE

(Ciona
intestinalis) 		PF00782
(DSPc)
PF10409
(PTEN_C2) 		4 VAL A 509
LEU A 568
VAL A 541
PHE A 529
 None
 0.98A 4lb0B-3v0iA:
undetectable		 4lb0B-3v0iA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsc PROTEIN CYSO

(Aeropyrum
pernix) 		PF00291
(PALP) 		4 VAL A 276
LEU A  68
VAL A  73
PHE A 243
 None
 0.94A 4lb0B-3vscA:
undetectable		 4lb0B-3vscA:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zid TUBULIN/FTSZ, GTPASE

(Methanothrix
thermoacetophila) 		PF00091
(Tubulin) 		4 VAL A 138
LEU A 105
VAL A   4
PHE A 107
 None
 1.02A 4lb0B-3zidA:
undetectable		 4lb0B-3zidA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a0s OCTENOYL-COA
REDUCTASE/CARBOXYLAS
E

(Streptomyces
cinnabarigriseus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 211
LEU A 374
VAL A 380
PHE A 240
 None
 0.88A 4lb0B-4a0sA:
undetectable		 4lb0B-4a0sA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b9p TYPE 3A
CELLULOSE-BINDING
DOMAIN PROTEIN

(Ruminiclostridium
thermocellum) 		PF00942
(CBM_3) 		4 VAL A  42
LEU A  29
VAL A 105
PHE A  92
 None
 1.03A 4lb0B-4b9pA:
undetectable		 4lb0B-4b9pA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bvt CYANURIC ACID
AMIDOHYDROLASE

(Pseudomonas sp.
ADP) 		PF09663
(Amido_AtzD_TrzD) 		4 VAL A  37
LEU A  63
VAL A  74
PHE A  80
 None
 0.98A 4lb0B-4bvtA:
undetectable		 4lb0B-4bvtA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fd9 BETA/GAMMA
CRYSTALLIN
DOMAIN-CONTAINING
PROTEIN 3

(Mus musculus) 		PF00030
(Crystall) 		4 VAL A  27
LEU A   7
VAL A   5
PHE A  86
 None
 1.04A 4lb0B-4fd9A:
undetectable		 4lb0B-4fd9A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3m RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Bacillus
subtilis) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		4 VAL A 295
LEU A 190
VAL A 287
PHE A 299
 None
 0.90A 4lb0B-4g3mA:
undetectable		 4lb0B-4g3mA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gpv PUTATIVE CELL
ADHESION PROTEIN

(Bacteroides
eggerthii) 		PF06321
(P_gingi_FimA) 		4 VAL A 108
LEU A 128
VAL A 122
PHE A 119
 None
 0.89A 4lb0B-4gpvA:
undetectable		 4lb0B-4gpvA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h3e SUPEROXIDE DISMUTASE

(Trypanosoma
cruzi) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 VAL A 132
LEU A 161
VAL A 190
PHE A 128
 None
 0.99A 4lb0B-4h3eA:
undetectable		 4lb0B-4h3eA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7q PHOSPHATIDYLINOSITOL
TRANSFER PROTEIN
PDR16

(Saccharomyces
cerevisiae) 		PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N) 		4 GLU A 151
VAL A 278
LEU A 241
VAL A 269
 None
 1.05A 4lb0B-4j7qA:
undetectable		 4lb0B-4j7qA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4js7 CELLULOSE BINDING
PROTEIN

(Clavibacter
michiganensis) 		PF01357
(Pollen_allerg_1)
PF03330
(DPBB_1) 		4 GLU A  41
VAL A  37
LEU A  52
VAL A  54
 None
 0.92A 4lb0B-4js7A:
undetectable		 4lb0B-4js7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kc3 INTERLEUKIN-1
RECEPTOR-LIKE 1

(Homo sapiens) 		PF07679
(I-set) 		4 VAL B  65
LEU B  72
VAL B  34
PHE B  74
 None
 1.05A 4lb0B-4kc3B:
undetectable		 4lb0B-4kc3B:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kqx KETOL-ACID
REDUCTOISOMERASE

(Slackia exigua) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 VAL A  89
LEU A 114
VAL A 135
PHE A 116
 None
 0.95A 4lb0B-4kqxA:
undetectable		 4lb0B-4kqxA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l5t INTERFERON-ACTIVABLE
PROTEIN 202

(Mus musculus) 		PF02760
(HIN) 		4 VAL A 286
LEU A 314
VAL A 332
PHE A 306
 None
 1.02A 4lb0B-4l5tA:
undetectable		 4lb0B-4l5tA:
19.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lb0 UNCHARACTERIZED
PROTEIN

(Agrobacterium
vitis) 		PF05544
(Pro_racemase) 		5 GLU A 233
VAL A 239
LEU A 266
VAL A 272
PHE A 278
 None
 0.14A 4lb0B-4lb0A:
61.7		 4lb0B-4lb0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nax GLUTATHIONE
S-TRANSFERASE,
N-TERMINAL DOMAIN
PROTEIN

(Pseudomonas
putida) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 GLU A 194
VAL A 193
LEU A 214
PHE A 204
 None
 1.05A 4lb0B-4naxA:
undetectable		 4lb0B-4naxA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ncn EUKARYOTIC
TRANSLATION
INITIATION FACTOR
5B-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2) 		4 VAL A 686
LEU A 712
VAL A 710
PHE A 690
 None
 1.06A 4lb0B-4ncnA:
undetectable		 4lb0B-4ncnA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nox EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT B

(Chaetomium
thermophilum) 		PF08662
(eIF2A) 		4 GLU A 444
VAL A 427
LEU A 408
VAL A 411
 None
 0.99A 4lb0B-4noxA:
undetectable		 4lb0B-4noxA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppz SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Neisseria
meningitidis) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 VAL A 282
LEU A 187
VAL A 254
PHE A 209
 None
 1.06A 4lb0B-4ppzA:
undetectable		 4lb0B-4ppzA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qo6 ADENYLATE
CYCLASE-LIKE PROTEIN

(Chlamydia
trachomatis) 		PF04972
(BON) 		4 VAL A 737
LEU A 721
VAL A 710
PHE A 733
 None
 1.05A 4lb0B-4qo6A:
undetectable		 4lb0B-4qo6A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjk ACETOLACTATE
SYNTHASE

(Bacillus
subtilis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 152
LEU A  25
VAL A  30
PHE A 156
 None
 1.00A 4lb0B-4rjkA:
undetectable		 4lb0B-4rjkA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ttp DEPHOSPHO-COA KINASE

(Legionella
pneumophila) 		PF01121
(CoaE) 		4 VAL A  24
LEU A 134
VAL A  11
PHE A  28
 None
 0.92A 4lb0B-4ttpA:
undetectable		 4lb0B-4ttpA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xvx ACYL-[ACYL-CARRIER-P
ROTEIN]
DEHYDROGENASE MBTN

(Mycobacterium
tuberculosis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 VAL A  22
LEU A  43
VAL A  48
PHE A  18
 None
 1.01A 4lb0B-4xvxA:
undetectable		 4lb0B-4xvxA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ypo KETOL-ACID
REDUCTOISOMERASE

(Mycobacterium
tuberculosis) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 VAL A  76
LEU A 101
VAL A 122
PHE A 103
 None
 0.99A 4lb0B-4ypoA:
undetectable		 4lb0B-4ypoA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ce5 TRIACYLGLYCEROL
LIPASE

(Geobacillus
thermocatenulatus) 		no annotation 4 VAL A 156
LEU A  71
VAL A  72
PHE A 155
 None
 1.05A 4lb0B-5ce5A:
undetectable		 4lb0B-5ce5A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e66 HEMAGGLUTININ-ESTERA
SE

(Influenza D
virus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 VAL A 111
LEU A 371
VAL A  76
PHE A  80
 None
 0.94A 4lb0B-5e66A:
undetectable		 4lb0B-5e66A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5epf PEROXIREDOXIN

(Mycobacterium
tuberculosis) 		PF00578
(AhpC-TSA) 		4 VAL A  40
LEU A 156
VAL A  69
PHE A  66
 None
 0.96A 4lb0B-5epfA:
undetectable		 4lb0B-5epfA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f4j PROTRUDING DOMAIN OF
GII.17 NOROVIRUS
CAPSID

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 VAL A 499
LEU A 507
VAL A 509
PHE A 487
 None
 0.91A 4lb0B-5f4jA:
undetectable		 4lb0B-5f4jA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Homo sapiens;
Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 VAL A 596
LEU A 550
VAL A 572
PHE A 594
 None
 1.02A 4lb0B-5i4eA:
undetectable		 4lb0B-5i4eA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ipw OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN, PUTATIVE

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		4 VAL A 193
LEU A 110
VAL A 208
PHE A 195
 None
 0.99A 4lb0B-5ipwA:
undetectable		 4lb0B-5ipwA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jij ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE

(Mycolicibacterium
thermoresistibile) 		PF00982
(Glyco_transf_20) 		4 GLU A 393
VAL A 390
LEU A 368
VAL A 363
 None
None
EDO  A 507 (-4.7A)
EDO  A 510 ( 4.2A)
 0.99A 4lb0B-5jijA:
undetectable		 4lb0B-5jijA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1h EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT B

(Homo sapiens) 		PF00076
(RRM_1)
PF08662
(eIF2A) 		4 GLU B 448
VAL B 431
LEU B 412
VAL B 415
 None
 1.03A 4lb0B-5k1hB:
undetectable		 4lb0B-5k1hB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kxf FLOWERING TIME
CONTROL PROTEIN FPA

(Arabidopsis
thaliana) 		PF07744
(SPOC) 		5 GLU A 465
VAL A 496
LEU A 468
VAL A 472
PHE A 498
 None
 1.35A 4lb0B-5kxfA:
undetectable		 4lb0B-5kxfA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE

(Jeotgalicoccus
sp. ATCC 8456) 		PF00067
(p450) 		4 VAL A 390
LEU A 395
VAL A 406
PHE A 410
 None
 0.97A 4lb0B-5m0oA:
undetectable		 4lb0B-5m0oA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mb4 GLCNAC SPECIFIC
LECTIN

(Psathyrella) 		PF13517
(VCBS) 		4 VAL A 267
LEU A 243
VAL A 286
PHE A 316
 None
 0.96A 4lb0B-5mb4A:
undetectable		 4lb0B-5mb4A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o30 PUTATIVE
OXIDOREDUCTASE

(Ilumatobacter
coccineus) 		PF13561
(adh_short_C2) 		4 VAL A 148
LEU A  23
VAL A  19
PHE A 150
 None
 1.03A 4lb0B-5o30A:
undetectable		 4lb0B-5o30A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyd CELLULASE, PUTATIVE,
CEL5D

(Cellvibrio
japonicus) 		no annotation 4 GLU A 321
VAL A 387
LEU A 204
PHE A 430
 None
 0.72A 4lb0B-5oydA:
undetectable		 4lb0B-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xh9 EXTRACELLULAR
INVERTASE

(Aspergillus
kawachii) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 VAL A 108
LEU A  67
VAL A 125
PHE A 171
 None
 1.02A 4lb0B-5xh9A:
undetectable		 4lb0B-5xh9A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xix ASPARAGINE--TRNA
LIGASE, CYTOPLASMIC

(Homo sapiens) 		no annotation 4 VAL A 252
LEU A 520
VAL A 338
PHE A 256
 None
 0.94A 4lb0B-5xixA:
undetectable		 4lb0B-5xixA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmd EPOXIDE HYDROLASE A

(Vigna radiata) 		no annotation 4 GLU A  20
VAL A  55
LEU A  90
VAL A  92
 None
 0.92A 4lb0B-5xmdA:
undetectable		 4lb0B-5xmdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yac TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5B

(Pyrococcus
abyssi) 		PF02475
(Met_10) 		4 VAL A 233
LEU A 206
VAL A 185
PHE A 208
 None
 1.05A 4lb0B-5yacA:
undetectable		 4lb0B-5yacA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6a91 -

(-) 		no annotation 4 VAL A 731
LEU A 258
VAL A 262
PHE A 726
 None
 0.89A 4lb0B-6a91A:
undetectable		 4lb0B-6a91A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aqj KETOL-ACID
REDUCTOISOMERASE
(NADP(+))

(Staphylococcus
aureus) 		no annotation 4 VAL A  78
LEU A 103
VAL A 124
PHE A 105
 None
 0.95A 4lb0B-6aqjA:
undetectable		 4lb0B-6aqjA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6baa ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 11

(Rattus
norvegicus) 		no annotation 4 VAL A  44
LEU A 233
VAL A 220
PHE A  35
 None
 0.94A 4lb0B-6baaA:
undetectable		 4lb0B-6baaA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8v COENZYME PQQ
SYNTHESIS PROTEIN E

(Methylobacterium
extorquens) 		no annotation 4 GLU A  74
LEU A  97
VAL A 120
PHE A 148
 None
 1.03A 4lb0B-6c8vA:
undetectable		 4lb0B-6c8vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6el1 YAXB

(Yersinia
enterocolitica) 		no annotation 4 VAL O 294
LEU O  57
VAL O  61
PHE O  22
 None
 1.04A 4lb0B-6el1O:
undetectable		 4lb0B-6el1O:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9pcy PLASTOCYANIN

(Phaseolus
vulgaris) 		PF00127
(Copper-bind) 		4 GLU A  25
VAL A  21
VAL A   3
PHE A  19
 None
 1.04A 4lb0B-9pcyA:
undetectable		 4lb0B-9pcyA:
16.49