SIMILAR PATTERNS OF AMINO ACIDS FOR 4L9Q_A_9TPA601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt4 | PHOSPHOSERINEAMINOTRANSFERASE (Bacilluscirculans) |
PF00266(Aminotran_5) | 5 | ALA A 336TYR A 286LEU A 304ARG A 361GLY A 362 | None | 1.28A | 4l9qA-1bt4A:0.0 | 4l9qA-1bt4A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dlj | UDP-GLUCOSEDEHYDROGENASE (Streptococcuspyogenes) |
PF00984(UDPG_MGDP_dh)PF03720(UDPG_MGDP_dh_C)PF03721(UDPG_MGDP_dh_N) | 5 | ARG A 157PRO A 155ALA A 184ILE A 194GLY A 196 | None | 1.07A | 4l9qA-1dljA:undetectable | 4l9qA-1dljA:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dm1 | MYOGLOBIN (Aplysialimacina) |
PF00042(Globin) | 5 | LEU A 88ALA A 10LYS A 132ILE A 138GLY A 101 | None | 1.25A | 4l9qA-1dm1A:2.4 | 4l9qA-1dm1A:12.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1x | 4-ALPHA-GLUCANOTRANSFERASE (Thermococcuslitoralis) |
PF03065(Glyco_hydro_57)PF09094(DUF1925)PF09095(DUF1926) | 5 | PRO A 15ILE A 10HIS A 212TYR A 31LEU A 54 | None | 1.28A | 4l9qA-1k1xA:0.1 | 4l9qA-1k1xA:21.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | ARG A 117ALA A 126ILE A 142HIS A 146ARG A 186GLY A 189 | None | 1.18A | 4l9qA-1tf0A:47.7 | 4l9qA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 7 | LEU A 115TYR A 138ILE A 142HIS A 146LEU A 182ARG A 186GLY A 189 | None | 0.72A | 4l9qA-1tf0A:47.7 | 4l9qA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | PRO A 118ALA A 126LYS A 137ILE A 142LEU A 182ARG A 186 | None | 0.82A | 4l9qA-1tf0A:47.7 | 4l9qA-1tf0A:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 9 | PRO A 118ALA A 126TYR A 138ILE A 142HIS A 146TYR A 161LEU A 182ARG A 186GLY A 189 | None | 0.54A | 4l9qA-1tf0A:47.7 | 4l9qA-1tf0A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tjr | BX1 (Zea mays) |
PF00290(Trp_syntA) | 5 | PRO A 142ALA A 156TYR A 107LEU A 184GLY A 291 | None | 1.30A | 4l9qA-1tjrA:undetectable | 4l9qA-1tjrA:19.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tvt | TRANSACTIVATORPROTEIN (Equineinfectiousanemia virus) |
PF00539(Tat) | 5 | LEU A 75ALA A 64LEU A 50ARG A 4GLY A 46 | None | 1.28A | 4l9qA-1tvtA:undetectable | 4l9qA-1tvtA:7.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ve2 | UROPORPHYRIN-IIIC-METHYLTRANSFERASE (Thermusthermophilus) |
PF00590(TP_methylase) | 5 | ARG A 83PRO A 89LYS A 21LEU A 84GLY A 48 | None | 1.28A | 4l9qA-1ve2A:undetectable | 4l9qA-1ve2A:19.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6f | ARYLAMINEN-ACETYLTRANSFERASE (Mycolicibacteriumsmegmatis) |
PF00797(Acetyltransf_2) | 5 | LEU A 221ARG A 222ILE A 255LEU A 44GLY A 67 | None | 1.26A | 4l9qA-1w6fA:undetectable | 4l9qA-1w6fA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w6f | ARYLAMINEN-ACETYLTRANSFERASE (Mycolicibacteriumsmegmatis) |
PF00797(Acetyltransf_2) | 5 | LEU A 221ARG A 222ILE A 255LEU A 44GLY A 68 | None | 1.33A | 4l9qA-1w6fA:undetectable | 4l9qA-1w6fA:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fjk | FRUCTOSE-BISPHOSPHATE ALDOLASE (Thermuscaldophilus) |
PF01116(F_bP_aldolase) | 5 | LEU A 207ALA A 47ILE A 243LEU A 9GLY A 16 | None | 1.34A | 4l9qA-2fjkA:undetectable | 4l9qA-2fjkA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hx1 | PREDICTED SUGARPHOSPHATASES OF THEHAD SUPERFAMILY (Cytophagahutchinsonii) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 5 | LEU A 135ALA A 55ILE A 190ARG A 197GLY A 195 | NoneNoneNoneNone CL A 306 ( 4.2A) | 1.12A | 4l9qA-2hx1A:undetectable | 4l9qA-2hx1A:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hzg | MANDELATERACEMASE/MUCONATELACTONIZINGENZYME/ENOLASESUPERFAMILY (Rhodobactersphaeroides) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | LEU A 353ALA A 138LEU A 316ARG A 355GLY A 321 | None | 1.34A | 4l9qA-2hzgA:undetectable | 4l9qA-2hzgA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kw7 | CONSERVED DOMAINPROTEIN (Porphyromonasgingivalis) |
PF04536(TPM_phosphatase) | 5 | LEU A 88ALA A 42ILE A 117LEU A 105GLY A 112 | None | 1.06A | 4l9qA-2kw7A:undetectable | 4l9qA-2kw7A:11.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9r | PROTEIN OF UNKNOWNFUNCTION (Shewanellabaltica) |
PF04222(DUF416) | 5 | LEU A 53ALA A 107LEU A 60ARG A 183GLY A 181 | None | 1.23A | 4l9qA-2q9rA:2.1 | 4l9qA-2q9rA:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qed | HYDROXYACYLGLUTATHIONE HYDROLASE (Salmonellaenterica) |
PF00753(Lactamase_B)PF16123(HAGH_C) | 5 | LEU A 176TYR A 188ILE A 213LEU A 169GLY A 133 | None | 1.28A | 4l9qA-2qedA:undetectable | 4l9qA-2qedA:16.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xnh | DNA TOPOISOMERASE2-BINDING PROTEIN 1 (Homo sapiens) |
PF00533(BRCT)PF12738(PTCB-BRCT) | 5 | LEU A 167PRO A 169TYR A 156LEU A 201GLY A 274 | NoneIOD A1299 ( 4.7A)NoneNoneNone | 1.32A | 4l9qA-2xnhA:undetectable | 4l9qA-2xnhA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xr1 | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR100 KD SUBUNIT (Methanosarcinamazei) |
PF07521(RMMBL)PF07650(KH_2)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 5 | LEU A 636ARG A 182ALA A 317ILE A 375LEU A 198 | None | 1.16A | 4l9qA-2xr1A:undetectable | 4l9qA-2xr1A:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ykf | PROBABLE SENSORHISTIDINE KINASEPDTAS (Mycobacteriumtuberculosis) |
PF12282(H_kinase_N) | 5 | ARG A 248PRO A 175ALA A 197LEU A 263GLY A 244 | None | 1.29A | 4l9qA-2ykfA:undetectable | 4l9qA-2ykfA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5x | FLAGELLIN (Salmonellaenterica) |
PF00669(Flagellin_N)PF00700(Flagellin_C)PF08884(Flagellin_D3) | 5 | LEU A 415ILE A 84LEU A 421ARG A 422GLY A 79 | None | 1.13A | 4l9qA-3a5xA:2.1 | 4l9qA-3a5xA:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3adf | MONOMERIC AZAMIGREEN (Galaxeafascicularis) |
PF01353(GFP) | 5 | LEU A 42ALA A 103TYR A 116ILE A 10GLY A 31 | NoneNoneCRQ A 64 ( 4.6A)NoneNone | 1.35A | 4l9qA-3adfA:undetectable | 4l9qA-3adfA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bh1 | UPF0371 PROTEINDIP2346 (Corynebacteriumdiphtheriae) |
PF08903(DUF1846) | 5 | LEU A 271ARG A 270ALA A 260HIS A 195TYR A 148 | None | 1.29A | 4l9qA-3bh1A:undetectable | 4l9qA-3bh1A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bzj | UV ENDONUCLEASE (Thermusthermophilus) |
PF03851(UvdE) | 5 | LEU A 219PRO A 261ALA A 264LEU A 213GLY A 209 | None | 1.33A | 4l9qA-3bzjA:undetectable | 4l9qA-3bzjA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cm0 | ADENYLATE KINASE (Thermusthermophilus) |
PF00406(ADK) | 5 | ARG A 73ALA A 6ILE A 38HIS A 42LEU A 69 | None | 1.14A | 4l9qA-3cm0A:undetectable | 4l9qA-3cm0A:17.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3daq | DIHYDRODIPICOLINATESYNTHASE (Staphylococcusaureus) |
PF00701(DHDPS) | 5 | LEU A 282ARG A 283ALA A 291ILE A 209LEU A 260 | None | 1.32A | 4l9qA-3daqA:undetectable | 4l9qA-3daqA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e1t | HALOGENASE (Chondromycescrocatus) |
PF04820(Trp_halogenase) | 5 | PRO A 495ILE A 58TYR A 321LEU A 325GLY A 18 | NoneNoneNoneNoneFAD A 600 (-3.4A) | 1.24A | 4l9qA-3e1tA:undetectable | 4l9qA-3e1tA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eaf | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (Aeropyrumpernix) |
PF13458(Peripla_BP_6) | 5 | LEU A 185PRO A 241ALA A 233TYR A 189ILE A 200 | None | 1.22A | 4l9qA-3eafA:undetectable | 4l9qA-3eafA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3egw | RESPIRATORY NITRATEREDUCTASE 1 ALPHACHAINRESPIRATORY NITRATEREDUCTASE 1 BETACHAIN (Escherichiacoli) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF13247(Fer4_11)PF14710(Nitr_red_alph_N)PF14711(Nitr_red_bet_C) | 5 | ALA B 114ILE A1183HIS A1184TYR A 781GLY A 721 | NoneNoneMD1 A1245 ( 4.6A)NoneNone | 1.31A | 4l9qA-3egwB:undetectable | 4l9qA-3egwB:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3enk | UDP-GLUCOSE4-EPIMERASE (Burkholderiapseudomallei) |
PF16363(GDP_Man_Dehyd) | 5 | ARG A 164ALA A 308TYR A 132LEU A 146GLY A 153 | None | 1.25A | 4l9qA-3enkA:undetectable | 4l9qA-3enkA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fms | TRANSCRIPTIONALREGULATOR, GNTRFAMILY (Thermotogamaritima) |
PF00392(GntR)PF07729(FCD) | 5 | LEU A 133ARG A 132ALA A 118ILE A 181GLY A 103 | None | 1.21A | 4l9qA-3fmsA:3.2 | 4l9qA-3fmsA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ics | COENZYME A-DISULFIDEREDUCTASE (Bacillusanthracis) |
PF00581(Rhodanese)PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 285TYR A 280ILE A 316HIS A 317GLY A 318 | None | 1.37A | 4l9qA-3icsA:undetectable | 4l9qA-3icsA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3igs | N-ACETYLMANNOSAMINE-6-PHOSPHATE2-EPIMERASE 2 (Salmonellaenterica) |
PF04131(NanE) | 5 | LEU A 170PRO A 166ALA A 193ILE A 150GLY A 106 | None | 1.30A | 4l9qA-3igsA:undetectable | 4l9qA-3igsA:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 5 | PRO A 171ALA A 36TYR A 6ILE A 187GLY A 190 | None | 1.22A | 4l9qA-3ju8A:undetectable | 4l9qA-3ju8A:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k2n | SIGMA-54-DEPENDENTTRANSCRIPTIONALREGULATOR (Chlorobaculumtepidum) |
PF13185(GAF_2) | 5 | ALA A 50ILE A 91HIS A 110LEU A 61GLY A 113 | None | 1.17A | 4l9qA-3k2nA:undetectable | 4l9qA-3k2nA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kdr | HK97 FAMILY PHAGEPORTAL PROTEIN (Corynebacteriumdiphtheriae) |
PF04860(Phage_portal) | 5 | LEU A 66ARG A 63ILE A 164HIS A 165GLY A 114 | NonePO4 A 1 ( 4.9A)NoneNoneNone | 1.35A | 4l9qA-3kdrA:2.9 | 4l9qA-3kdrA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pc3 | CG1753, ISOFORM A (Drosophilamelanogaster) |
PF00291(PALP)PF00571(CBS) | 5 | ALA A 330ILE A 233HIS A 201LEU A 58GLY A 204 | None | 1.28A | 4l9qA-3pc3A:undetectable | 4l9qA-3pc3A:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r4i | CITRATE LYASE (Paraburkholderiaxenovorans) |
PF03328(HpcH_HpaI) | 5 | LEU A 309ARG A 310ALA A 3ILE A 278LEU A 10 | None | 1.21A | 4l9qA-3r4iA:undetectable | 4l9qA-3r4iA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rim | TRANSKETOLASE (Mycobacteriumtuberculosis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ARG A 681ALA A 601ILE A 667HIS A 669GLY A 671 | None | 1.13A | 4l9qA-3rimA:undetectable | 4l9qA-3rimA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sze | SERINE PROTEASE ESPP (Escherichiacoli) |
PF02395(Peptidase_S6) | 5 | LEU A 428ALA A 459ILE A 448LEU A 434GLY A 451 | None | 1.25A | 4l9qA-3szeA:undetectable | 4l9qA-3szeA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vr1 | PEPTIDE CHAINRELEASE FACTOR 3 (Desulfovibriovulgaris) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF16658(RF3_C) | 5 | LEU A 218TYR A 182ILE A 206ARG A 226GLY A 208 | None | 1.25A | 4l9qA-3vr1A:undetectable | 4l9qA-3vr1A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wn6 | ALPHA-AMYLASE (Oryza sativa) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 5 | ALA A 280ILE A 396LEU A 377ARG A 378GLY A 393 | None | 1.34A | 4l9qA-3wn6A:undetectable | 4l9qA-3wn6A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zul | FLUORESCENT PROTEINDRONPA (Echinophylliasp. SC22) |
PF01353(GFP) | 5 | LEU A 42ALA A 103TYR A 116ILE A 10GLY A 31 | NoneNoneGYC A 63 ( 4.8A)NoneNone | 1.35A | 4l9qA-3zulA:undetectable | 4l9qA-3zulA:16.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7g | BETA-N-ACETYLHEXOSAMINIDASE (Streptomycescoelicolor) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b) | 5 | LEU A 108ARG A 109ALA A 39TYR A 82ILE A 133 | None | 1.33A | 4l9qA-4c7gA:undetectable | 4l9qA-4c7gA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cr4 | 26S PROTEASEREGULATORY SUBUNIT6B HOMOLOG26S PROTEASEREGULATORY SUBUNIT 8HOMOLOG (Saccharomycescerevisiae) |
PF00004(AAA) | 5 | LEU J 197ALA J 293HIS J 331ARG K 333GLY J 360 | None | 1.35A | 4l9qA-4cr4J:2.1 | 4l9qA-4cr4J:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6w | CLBP PEPTIDASE (Escherichiacoli) |
PF00144(Beta-lactamase) | 5 | LEU A 340ARG A 341HIS A 279LEU A 370GLY A 67 | None | 1.24A | 4l9qA-4e6wA:undetectable | 4l9qA-4e6wA:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fys | AMINOPEPTIDASE N (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 5 | LEU A 390ALA A 281ILE A 300LEU A 338GLY A 297 | None | 1.27A | 4l9qA-4fysA:undetectable | 4l9qA-4fysA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gg2 | GAMMA-GLUTAMYLTRANSPEPTIDASE 1 HEAVYCHAIN (Homo sapiens) |
PF01019(G_glu_transpept) | 5 | PRO A 159ALA A 57TYR A 141ILE A 138GLY A 86 | None | 1.08A | 4l9qA-4gg2A:undetectable | 4l9qA-4gg2A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gnr | ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN-BRANCHEDCHAIN AMINO ACIDTRANSPORT (Streptococcuspneumoniae) |
PF13458(Peripla_BP_6) | 5 | ALA A 120TYR A 189ILE A 193TYR A 238GLY A 260 | NoneILE A 401 (-4.0A)NoneILE A 401 (-4.6A)None | 1.34A | 4l9qA-4gnrA:undetectable | 4l9qA-4gnrA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gxr | MALONYL COASYNTHETASE,BENZOATE-COA LIGASECHIMERIC PROTEIN (Paraburkholderiaxenovorans;Rhodopseudomonaspalustris) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 5 | LEU A 175ALA A 214TYR A 70LEU A 5GLY A 78 | None | 1.26A | 4l9qA-4gxrA:undetectable | 4l9qA-4gxrA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jy4 | PGT121 HEAVY CHAIN (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 5 | LEU B 69ILE B 37TYR B 90LEU B 20GLY B 102 | None | 1.35A | 4l9qA-4jy4B:undetectable | 4l9qA-4jy4B:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n0l | PREDICTED COMPONENTOF ATHERMOPHILE-SPECIFICDNA REPAIR SYSTEM,CONTAINS A RAMPDOMAIN (Methanopyruskandleri) |
PF03787(RAMPs) | 5 | LEU A 136PRO A 154ILE A 128LEU A 160GLY A 125 | None | 1.33A | 4l9qA-4n0lA:undetectable | 4l9qA-4n0lA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oen | SECOND SUBSTRATEBINDING DOMAIN OFPUTATIVE AMINO ACIDABC TRANSPORTER (Streptococcuspneumoniae) |
PF00497(SBP_bac_3) | 5 | LEU A 357ILE A 417TYR A 409LEU A 437GLY A 415 | None | 1.24A | 4l9qA-4oenA:undetectable | 4l9qA-4oenA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p1c | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN A (Pseudomonasmendocina) |
PF02332(Phenol_Hydrox) | 5 | LEU A 393PRO A 403ALA A 171ILE A 459GLY A 457 | None | 1.37A | 4l9qA-4p1cA:undetectable | 4l9qA-4p1cA:20.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 6 | PRO A 118ALA A 126TYR A 138HIS A 146TYR A 161LEU A 182 | None | 0.97A | 4l9qA-4po0A:49.8 | 4l9qA-4po0A:74.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q9t | NUCLEOPORIN NUP133 (Vanderwaltozymapolyspora) |
PF08801(Nucleoporin_N) | 5 | LEU A 288ALA A 422ILE A 286LEU A 310GLY A 307 | None | 1.25A | 4l9qA-4q9tA:undetectable | 4l9qA-4q9tA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s12 | N-ACETYLMURAMIC ACID6-PHOSPHATE ETHERASE (Yersiniaenterocolitica) |
PF01380(SIS) | 5 | LEU A 129ALA A 163LEU A 65ARG A 64GLY A 62 | None | 1.17A | 4l9qA-4s12A:undetectable | 4l9qA-4s12A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4twi | NAD-DEPENDENTPROTEIN DEACYLASE 1 (Archaeoglobusfulgidus) |
PF02146(SIR2) | 5 | LEU A 18ALA A 79ILE A 207LEU A 15GLY A 205 | None | 1.27A | 4l9qA-4twiA:undetectable | 4l9qA-4twiA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tza | FLUORESCENT PROTEIN (syntheticconstruct) |
no annotation | 5 | LEU C 42ALA C 103TYR C 116ILE C 10GLY C 31 | NoneNoneCRQ C 62 ( 4.7A)NoneNone | 1.32A | 4l9qA-4tzaC:undetectable | 4l9qA-4tzaC:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4um8 | INTEGRIN BETA-6 (Homo sapiens) |
PF00362(Integrin_beta)PF17205(PSI_integrin) | 5 | LEU B 121ALA B 331ILE B 239HIS B 195LEU B 118 | None | 1.32A | 4l9qA-4um8B:undetectable | 4l9qA-4um8B:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uoz | BETA-GALACTOSIDASE (Bifidobacteriumanimalis) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 5 | LEU A 538ALA A 589TYR A 504ILE A 439LEU A 608 | None | 1.34A | 4l9qA-4uozA:undetectable | 4l9qA-4uozA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uym | 14-ALPHA STEROLDEMETHYLASE (Aspergillusfumigatus) |
PF00067(p450) | 6 | LEU A 417ALA A 81LYS A 74TYR A 73HIS A 370ARG A 368 | None | 1.35A | 4l9qA-4uymA:undetectable | 4l9qA-4uymA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbt | PROBABLEHISTIDINOL-PHOSPHATEAMINOTRANSFERASE (Sinorhizobiummeliloti) |
PF00155(Aminotran_1_2) | 5 | PRO A 207ALA A 182ILE A 94LEU A 239GLY A 236 | NoneNonePLP A 401 (-3.6A)NoneNone | 1.25A | 4l9qA-4wbtA:undetectable | 4l9qA-4wbtA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wrw | URACIL-DNAGLYCOSYLASE (Mycobacteriumtuberculosis) |
PF03167(UDG) | 5 | LEU A 226ARG A 225ALA A 103ARG A 121GLY A 122 | NoneNoneGOL A 304 ( 3.7A)NoneNone | 1.19A | 4l9qA-4wrwA:undetectable | 4l9qA-4wrwA:16.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xa9 | GALA PROTEIN TYPE 1,3 OR 4 (Legionellapneumophila) |
PF13516(LRR_6) | 5 | LEU A 122ALA A 111ILE A 167LEU A 149GLY A 193 | None | 1.27A | 4l9qA-4xa9A:undetectable | 4l9qA-4xa9A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0i | 4-AMINOBUTYRATEAMINOTRANSFERASE,MITOCHONDRIAL (Sus scrofa) |
PF00202(Aminotran_3) | 5 | ARG A 222ALA A 218ILE A 267ARG A 406GLY A 407 | None | 1.37A | 4l9qA-4y0iA:undetectable | 4l9qA-4y0iA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y0i | 4-AMINOBUTYRATEAMINOTRANSFERASE,MITOCHONDRIAL (Sus scrofa) |
PF00202(Aminotran_3) | 5 | ARG A 222ILE A 267LEU A 223ARG A 406GLY A 407 | None | 1.02A | 4l9qA-4y0iA:undetectable | 4l9qA-4y0iA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yj1 | UNCHARACTERIZEDPROTEIN (Trypanosomabrucei) |
PF09818(ABC_ATPase) | 5 | ALA A 325ILE A 649HIS A 648LEU A 405GLY A 402 | None | 1.22A | 4l9qA-4yj1A:undetectable | 4l9qA-4yj1A:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yxt | POLYKETIDEBIOSYNTHESIS3-HYDROXY-3-METHYLGLUTARYL-ACP SYNTHASEPKSG (Bacillussubtilis) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 5 | LEU A 229ALA A 260LYS A 267TYR A 240GLY A 237 | None | 1.06A | 4l9qA-4yxtA:undetectable | 4l9qA-4yxtA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z26 | PUTATIVE GMC-TYPEOXIDOREDUCTASE R135 (Acanthamoebapolyphagamimivirus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | ARG A 27ALA A 232ILE A 632LEU A 638GLY A 634 | None | 1.20A | 4l9qA-4z26A:undetectable | 4l9qA-4z26A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d9a | POLYMERASE BASICPROTEIN 2RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Cvirus) |
PF00602(Flu_PB1)PF00604(Flu_PB2) | 5 | PRO B 631ALA C 71ILE B 576ARG B 573GLY B 572 | None | 1.35A | 4l9qA-5d9aB:3.6 | 4l9qA-5d9aB:21.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 5 | ALA A 125TYR A 137HIS A 145TYR A 160LEU A 181 | None | 0.35A | 4l9qA-5dqfA:50.5 | 4l9qA-5dqfA:76.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f1u | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Campylobacterjejuni) |
PF00701(DHDPS) | 5 | LEU A 155ILE A 126HIS A 122LEU A 135GLY A 82 | None | 1.26A | 4l9qA-5f1uA:undetectable | 4l9qA-5f1uA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f8v | AMINOTRANSFERASE,CLASS V FAMILYPROTEIN (Trichomonasvaginalis) |
PF00266(Aminotran_5) | 5 | LEU A 62PRO A 186ALA A 272ILE A 257GLY A 205 | None | 1.18A | 4l9qA-5f8vA:undetectable | 4l9qA-5f8vA:21.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | ALA A 126LYS A 137ILE A 142HIS A 146TYR A 161 | None | 1.00A | 4l9qA-5ghkA:47.3 | 4l9qA-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | ALA A 126TYR A 138ILE A 142HIS A 146TYR A 161 | None | 0.60A | 4l9qA-5ghkA:47.3 | 4l9qA-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | LYS A 137ILE A 142HIS A 146TYR A 161ARG A 186 | None | 0.94A | 4l9qA-5ghkA:47.3 | 4l9qA-5ghkA:79.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | TYR A 138ILE A 142HIS A 146TYR A 161ARG A 186 | None | 0.77A | 4l9qA-5ghkA:47.3 | 4l9qA-5ghkA:79.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5giv | CARBOXYPEPTIDASE 1 (Deinococcusradiodurans) |
PF02074(Peptidase_M32) | 5 | LEU A 305ARG A 308ALA A 315TYR A 221LEU A 265 | None | 1.08A | 4l9qA-5givA:1.7 | 4l9qA-5givA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gt1 | CHOLINE BINDINGPROTEIN A (Lactobacillussalivarius) |
PF01551(Peptidase_M23) | 5 | PRO A 368ILE A 478TYR A 442LEU A 474GLY A 397 | None | 1.27A | 4l9qA-5gt1A:undetectable | 4l9qA-5gt1A:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5idu | ACYL-COADEHYDROGENASE DOMAINPROTEIN (Paraburkholderiaphymatum) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | LEU A 112ALA A 134ILE A 77LEU A 123GLY A 74 | None | 1.14A | 4l9qA-5iduA:2.3 | 4l9qA-5iduA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikg | DYE-DECOLORIZINGPEROXIDASE (Auriculariaauricula-judae) |
PF04261(Dyp_perox) | 5 | ARG A 217ALA A 151ILE A 114TYR A 147GLY A 111 | None | 1.35A | 4l9qA-5ikgA:undetectable | 4l9qA-5ikgA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jsc | PUTATIVE ACYL-COADEHYDROGENASE (Paraburkholderiaxenovorans) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | LEU A 113ALA A 135ILE A 78LEU A 124GLY A 75 | None | 1.25A | 4l9qA-5jscA:2.3 | 4l9qA-5jscA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ktl | 4-HYDROXY-TETRAHYDRODIPICOLINATESYNTHASE (Trichormusvariabilis) |
PF00701(DHDPS) | 5 | LEU A 154ILE A 124HIS A 120LEU A 134GLY A 80 | NoneNoneNoneKPI A 164 ( 4.8A)None | 1.28A | 4l9qA-5ktlA:undetectable | 4l9qA-5ktlA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lk7 | VP1 (Slow beeparalysis virus) |
PF08762(CRPV_capsid) | 5 | TYR A 221ILE A 91TYR A 43LEU A 72GLY A 89 | None | 1.14A | 4l9qA-5lk7A:undetectable | 4l9qA-5lk7A:16.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lrb | ALPHA-1,4 GLUCANPHOSPHORYLASE (Hordeum vulgare) |
PF00343(Phosphorylase) | 5 | LEU A 480ARG A 569ALA A 490ILE A 450GLY A 577 | None | 1.27A | 4l9qA-5lrbA:undetectable | 4l9qA-5lrbA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mxf | PHOTORHABDUSASYMBIOTICA LECTINPHL (Photorhabdusasymbiotica) |
PF03984(DUF346) | 5 | ALA A 276ILE A 32LEU A 294ARG A 288GLY A 337 | NoneNoneNoneNoneMFU A 401 (-3.2A) | 1.27A | 4l9qA-5mxfA:undetectable | 4l9qA-5mxfA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfq | EPOXIDE HYDROLASEBELONGING TOALPHA/BETA HYDROLASESUPERFAMILYMETAGENOMIC FROMTOMSK SAMPLE (metagenome) |
no annotation | 5 | LEU A 237PRO A 266ILE A 98LEU A 242GLY A 100 | None | 1.26A | 4l9qA-5nfqA:undetectable | 4l9qA-5nfqA:8.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 5 | LYS A 136TYR A 137HIS A 145TYR A 160ARG A 185 | None | 1.13A | 4l9qA-5oriA:50.8 | 4l9qA-5oriA:74.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t9c | GLYCEROPHOSPHORYLDIESTERPHOSPHODIESTERASE (Bacillussubtilis) |
PF03009(GDPD) | 5 | LEU E 32ALA E 61TYR E 150ILE E 186GLY E 233 | None | 1.17A | 4l9qA-5t9cE:undetectable | 4l9qA-5t9cE:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vys | GDP-MANNOSE4,6-DEHYDRATASE /GDP-4-AMINO-4,6-DIDEOXY-D-MANNOSEFORMYLTRANSFERASE (Brucellamelitensis) |
PF00551(Formyl_trans_N) | 5 | PRO A 228ILE A 169HIS A 86ARG A 45GLY A 15 | NoneNoneNoneGDP A 303 (-2.6A)None | 1.33A | 4l9qA-5vysA:undetectable | 4l9qA-5vysA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wug | BETA-GLUCOSIDASE (Paenibacillusbarengoltzii) |
no annotation | 5 | ALA A 451TYR A 695ILE A 627ARG A 288GLY A 286 | None | 1.15A | 4l9qA-5wugA:undetectable | 4l9qA-5wugA:7.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysb | LIN1841 PROTEIN (Listeriainnocua) |
no annotation | 5 | LEU A 289PRO A 167ALA A 177TYR A 231GLY A 208 | NoneNoneNoneNone ZN A 508 ( 4.7A) | 1.00A | 4l9qA-5ysbA:undetectable | 4l9qA-5ysbA:9.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 6 | LEU A 115PRO A 118ALA A 126TYR A 138HIS A 146TYR A 161 | None | 0.90A | 4l9qA-5yxeA:45.7 | 4l9qA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 6 | PRO A 118ALA A 126TYR A 138ILE A 142HIS A 146TYR A 161 | None | 0.47A | 4l9qA-5yxeA:45.7 | 4l9qA-5yxeA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ehs | HYDROGENASE-2 LARGECHAIN (Escherichiacoli) |
no annotation | 5 | LEU L 235ARG L 239ALA L 98TYR L 443ILE L 447 | None | 1.30A | 4l9qA-6ehsL:0.7 | 4l9qA-6ehsL:7.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1 (Saccharomycescerevisiae) |
no annotation | 5 | PRO A 932ALA A1000TYR A 916ILE A1089GLY A1093 | None | 1.13A | 4l9qA-6f42A:2.3 | 4l9qA-6f42A:11.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g3u | - (-) |
no annotation | 5 | PRO A 115ALA A 125ILE A 265HIS A 269GLY A 453 | None | 1.06A | 4l9qA-6g3uA:3.2 | 4l9qA-6g3uA:undetectable |