SIMILAR PATTERNS OF AMINO ACIDS FOR 4L9Q_A_9TPA601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bt4 PHOSPHOSERINE
AMINOTRANSFERASE


(Bacillus
circulans)
PF00266
(Aminotran_5)
5 ALA A 336
TYR A 286
LEU A 304
ARG A 361
GLY A 362
None
1.28A 4l9qA-1bt4A:
0.0
4l9qA-1bt4A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlj UDP-GLUCOSE
DEHYDROGENASE


(Streptococcus
pyogenes)
PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N)
5 ARG A 157
PRO A 155
ALA A 184
ILE A 194
GLY A 196
None
1.07A 4l9qA-1dljA:
undetectable
4l9qA-1dljA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dm1 MYOGLOBIN

(Aplysia
limacina)
PF00042
(Globin)
5 LEU A  88
ALA A  10
LYS A 132
ILE A 138
GLY A 101
None
1.25A 4l9qA-1dm1A:
2.4
4l9qA-1dm1A:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1x 4-ALPHA-GLUCANOTRANS
FERASE


(Thermococcus
litoralis)
PF03065
(Glyco_hydro_57)
PF09094
(DUF1925)
PF09095
(DUF1926)
5 PRO A  15
ILE A  10
HIS A 212
TYR A  31
LEU A  54
None
1.28A 4l9qA-1k1xA:
0.1
4l9qA-1k1xA:
21.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
6 ARG A 117
ALA A 126
ILE A 142
HIS A 146
ARG A 186
GLY A 189
None
1.18A 4l9qA-1tf0A:
47.7
4l9qA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
7 LEU A 115
TYR A 138
ILE A 142
HIS A 146
LEU A 182
ARG A 186
GLY A 189
None
0.72A 4l9qA-1tf0A:
47.7
4l9qA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
6 PRO A 118
ALA A 126
LYS A 137
ILE A 142
LEU A 182
ARG A 186
None
0.82A 4l9qA-1tf0A:
47.7
4l9qA-1tf0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
9 PRO A 118
ALA A 126
TYR A 138
ILE A 142
HIS A 146
TYR A 161
LEU A 182
ARG A 186
GLY A 189
None
0.54A 4l9qA-1tf0A:
47.7
4l9qA-1tf0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjr BX1

(Zea mays)
PF00290
(Trp_syntA)
5 PRO A 142
ALA A 156
TYR A 107
LEU A 184
GLY A 291
None
1.30A 4l9qA-1tjrA:
undetectable
4l9qA-1tjrA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tvt TRANSACTIVATOR
PROTEIN


(Equine
infectious
anemia virus)
PF00539
(Tat)
5 LEU A  75
ALA A  64
LEU A  50
ARG A   4
GLY A  46
None
1.28A 4l9qA-1tvtA:
undetectable
4l9qA-1tvtA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve2 UROPORPHYRIN-III
C-METHYLTRANSFERASE


(Thermus
thermophilus)
PF00590
(TP_methylase)
5 ARG A  83
PRO A  89
LYS A  21
LEU A  84
GLY A  48
None
1.28A 4l9qA-1ve2A:
undetectable
4l9qA-1ve2A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6f ARYLAMINE
N-ACETYLTRANSFERASE


(Mycolicibacterium
smegmatis)
PF00797
(Acetyltransf_2)
5 LEU A 221
ARG A 222
ILE A 255
LEU A  44
GLY A  67
None
1.26A 4l9qA-1w6fA:
undetectable
4l9qA-1w6fA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6f ARYLAMINE
N-ACETYLTRANSFERASE


(Mycolicibacterium
smegmatis)
PF00797
(Acetyltransf_2)
5 LEU A 221
ARG A 222
ILE A 255
LEU A  44
GLY A  68
None
1.33A 4l9qA-1w6fA:
undetectable
4l9qA-1w6fA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fjk FRUCTOSE-BISPHOSPHAT
E ALDOLASE


(Thermus
caldophilus)
PF01116
(F_bP_aldolase)
5 LEU A 207
ALA A  47
ILE A 243
LEU A   9
GLY A  16
None
1.34A 4l9qA-2fjkA:
undetectable
4l9qA-2fjkA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hx1 PREDICTED SUGAR
PHOSPHATASES OF THE
HAD SUPERFAMILY


(Cytophaga
hutchinsonii)
PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6)
5 LEU A 135
ALA A  55
ILE A 190
ARG A 197
GLY A 195
None
None
None
None
CL  A 306 ( 4.2A)
1.12A 4l9qA-2hx1A:
undetectable
4l9qA-2hx1A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzg MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME/ENOLASE
SUPERFAMILY


(Rhodobacter
sphaeroides)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 LEU A 353
ALA A 138
LEU A 316
ARG A 355
GLY A 321
None
1.34A 4l9qA-2hzgA:
undetectable
4l9qA-2hzgA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kw7 CONSERVED DOMAIN
PROTEIN


(Porphyromonas
gingivalis)
PF04536
(TPM_phosphatase)
5 LEU A  88
ALA A  42
ILE A 117
LEU A 105
GLY A 112
None
1.06A 4l9qA-2kw7A:
undetectable
4l9qA-2kw7A:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q9r PROTEIN OF UNKNOWN
FUNCTION


(Shewanella
baltica)
PF04222
(DUF416)
5 LEU A  53
ALA A 107
LEU A  60
ARG A 183
GLY A 181
None
1.23A 4l9qA-2q9rA:
2.1
4l9qA-2q9rA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qed HYDROXYACYLGLUTATHIO
NE HYDROLASE


(Salmonella
enterica)
PF00753
(Lactamase_B)
PF16123
(HAGH_C)
5 LEU A 176
TYR A 188
ILE A 213
LEU A 169
GLY A 133
None
1.28A 4l9qA-2qedA:
undetectable
4l9qA-2qedA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xnh DNA TOPOISOMERASE
2-BINDING PROTEIN 1


(Homo sapiens)
PF00533
(BRCT)
PF12738
(PTCB-BRCT)
5 LEU A 167
PRO A 169
TYR A 156
LEU A 201
GLY A 274
None
IOD  A1299 ( 4.7A)
None
None
None
1.32A 4l9qA-2xnhA:
undetectable
4l9qA-2xnhA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr1 CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
100 KD SUBUNIT


(Methanosarcina
mazei)
PF07521
(RMMBL)
PF07650
(KH_2)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7)
5 LEU A 636
ARG A 182
ALA A 317
ILE A 375
LEU A 198
None
1.16A 4l9qA-2xr1A:
undetectable
4l9qA-2xr1A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ykf PROBABLE SENSOR
HISTIDINE KINASE
PDTAS


(Mycobacterium
tuberculosis)
PF12282
(H_kinase_N)
5 ARG A 248
PRO A 175
ALA A 197
LEU A 263
GLY A 244
None
1.29A 4l9qA-2ykfA:
undetectable
4l9qA-2ykfA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5x FLAGELLIN

(Salmonella
enterica)
PF00669
(Flagellin_N)
PF00700
(Flagellin_C)
PF08884
(Flagellin_D3)
5 LEU A 415
ILE A  84
LEU A 421
ARG A 422
GLY A  79
None
1.13A 4l9qA-3a5xA:
2.1
4l9qA-3a5xA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3adf MONOMERIC AZAMI
GREEN


(Galaxea
fascicularis)
PF01353
(GFP)
5 LEU A  42
ALA A 103
TYR A 116
ILE A  10
GLY A  31
None
None
CRQ  A  64 ( 4.6A)
None
None
1.35A 4l9qA-3adfA:
undetectable
4l9qA-3adfA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh1 UPF0371 PROTEIN
DIP2346


(Corynebacterium
diphtheriae)
PF08903
(DUF1846)
5 LEU A 271
ARG A 270
ALA A 260
HIS A 195
TYR A 148
None
1.29A 4l9qA-3bh1A:
undetectable
4l9qA-3bh1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzj UV ENDONUCLEASE

(Thermus
thermophilus)
PF03851
(UvdE)
5 LEU A 219
PRO A 261
ALA A 264
LEU A 213
GLY A 209
None
1.33A 4l9qA-3bzjA:
undetectable
4l9qA-3bzjA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cm0 ADENYLATE KINASE

(Thermus
thermophilus)
PF00406
(ADK)
5 ARG A  73
ALA A   6
ILE A  38
HIS A  42
LEU A  69
None
1.14A 4l9qA-3cm0A:
undetectable
4l9qA-3cm0A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daq DIHYDRODIPICOLINATE
SYNTHASE


(Staphylococcus
aureus)
PF00701
(DHDPS)
5 LEU A 282
ARG A 283
ALA A 291
ILE A 209
LEU A 260
None
1.32A 4l9qA-3daqA:
undetectable
4l9qA-3daqA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e1t HALOGENASE

(Chondromyces
crocatus)
PF04820
(Trp_halogenase)
5 PRO A 495
ILE A  58
TYR A 321
LEU A 325
GLY A  18
None
None
None
None
FAD  A 600 (-3.4A)
1.24A 4l9qA-3e1tA:
undetectable
4l9qA-3e1tA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eaf ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN


(Aeropyrum
pernix)
PF13458
(Peripla_BP_6)
5 LEU A 185
PRO A 241
ALA A 233
TYR A 189
ILE A 200
None
1.22A 4l9qA-3eafA:
undetectable
4l9qA-3eafA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN
RESPIRATORY NITRATE
REDUCTASE 1 BETA
CHAIN


(Escherichia
coli)
PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF13247
(Fer4_11)
PF14710
(Nitr_red_alph_N)
PF14711
(Nitr_red_bet_C)
5 ALA B 114
ILE A1183
HIS A1184
TYR A 781
GLY A 721
None
None
MD1  A1245 ( 4.6A)
None
None
1.31A 4l9qA-3egwB:
undetectable
4l9qA-3egwB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3enk UDP-GLUCOSE
4-EPIMERASE


(Burkholderia
pseudomallei)
PF16363
(GDP_Man_Dehyd)
5 ARG A 164
ALA A 308
TYR A 132
LEU A 146
GLY A 153
None
1.25A 4l9qA-3enkA:
undetectable
4l9qA-3enkA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fms TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY


(Thermotoga
maritima)
PF00392
(GntR)
PF07729
(FCD)
5 LEU A 133
ARG A 132
ALA A 118
ILE A 181
GLY A 103
None
1.21A 4l9qA-3fmsA:
3.2
4l9qA-3fmsA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ics COENZYME A-DISULFIDE
REDUCTASE


(Bacillus
anthracis)
PF00581
(Rhodanese)
PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2)
5 ALA A 285
TYR A 280
ILE A 316
HIS A 317
GLY A 318
None
1.37A 4l9qA-3icsA:
undetectable
4l9qA-3icsA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igs N-ACETYLMANNOSAMINE-
6-PHOSPHATE
2-EPIMERASE 2


(Salmonella
enterica)
PF04131
(NanE)
5 LEU A 170
PRO A 166
ALA A 193
ILE A 150
GLY A 106
None
1.30A 4l9qA-3igsA:
undetectable
4l9qA-3igsA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ju8 SUCCINYLGLUTAMIC
SEMIALDEHYDE
DEHYDROGENASE


(Pseudomonas
aeruginosa)
PF00171
(Aldedh)
5 PRO A 171
ALA A  36
TYR A   6
ILE A 187
GLY A 190
None
1.22A 4l9qA-3ju8A:
undetectable
4l9qA-3ju8A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2n SIGMA-54-DEPENDENT
TRANSCRIPTIONAL
REGULATOR


(Chlorobaculum
tepidum)
PF13185
(GAF_2)
5 ALA A  50
ILE A  91
HIS A 110
LEU A  61
GLY A 113
None
1.17A 4l9qA-3k2nA:
undetectable
4l9qA-3k2nA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kdr HK97 FAMILY PHAGE
PORTAL PROTEIN


(Corynebacterium
diphtheriae)
PF04860
(Phage_portal)
5 LEU A  66
ARG A  63
ILE A 164
HIS A 165
GLY A 114
None
PO4  A   1 ( 4.9A)
None
None
None
1.35A 4l9qA-3kdrA:
2.9
4l9qA-3kdrA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pc3 CG1753, ISOFORM A

(Drosophila
melanogaster)
PF00291
(PALP)
PF00571
(CBS)
5 ALA A 330
ILE A 233
HIS A 201
LEU A  58
GLY A 204
None
1.28A 4l9qA-3pc3A:
undetectable
4l9qA-3pc3A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r4i CITRATE LYASE

(Paraburkholderia
xenovorans)
PF03328
(HpcH_HpaI)
5 LEU A 309
ARG A 310
ALA A   3
ILE A 278
LEU A  10
None
1.21A 4l9qA-3r4iA:
undetectable
4l9qA-3r4iA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rim TRANSKETOLASE

(Mycobacterium
tuberculosis)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
5 ARG A 681
ALA A 601
ILE A 667
HIS A 669
GLY A 671
None
1.13A 4l9qA-3rimA:
undetectable
4l9qA-3rimA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sze SERINE PROTEASE ESPP

(Escherichia
coli)
PF02395
(Peptidase_S6)
5 LEU A 428
ALA A 459
ILE A 448
LEU A 434
GLY A 451
None
1.25A 4l9qA-3szeA:
undetectable
4l9qA-3szeA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3


(Desulfovibrio
vulgaris)
PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C)
5 LEU A 218
TYR A 182
ILE A 206
ARG A 226
GLY A 208
None
1.25A 4l9qA-3vr1A:
undetectable
4l9qA-3vr1A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wn6 ALPHA-AMYLASE

(Oryza sativa)
PF00128
(Alpha-amylase)
PF07821
(Alpha-amyl_C2)
5 ALA A 280
ILE A 396
LEU A 377
ARG A 378
GLY A 393
None
1.34A 4l9qA-3wn6A:
undetectable
4l9qA-3wn6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zul FLUORESCENT PROTEIN
DRONPA


(Echinophyllia
sp. SC22)
PF01353
(GFP)
5 LEU A  42
ALA A 103
TYR A 116
ILE A  10
GLY A  31
None
None
GYC  A  63 ( 4.8A)
None
None
1.35A 4l9qA-3zulA:
undetectable
4l9qA-3zulA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7g BETA-N-ACETYLHEXOSAM
INIDASE


(Streptomyces
coelicolor)
PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
5 LEU A 108
ARG A 109
ALA A  39
TYR A  82
ILE A 133
None
1.33A 4l9qA-4c7gA:
undetectable
4l9qA-4c7gA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cr4 26S PROTEASE
REGULATORY SUBUNIT
6B HOMOLOG
26S PROTEASE
REGULATORY SUBUNIT 8
HOMOLOG


(Saccharomyces
cerevisiae)
PF00004
(AAA)
5 LEU J 197
ALA J 293
HIS J 331
ARG K 333
GLY J 360
None
1.35A 4l9qA-4cr4J:
2.1
4l9qA-4cr4J:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6w CLBP PEPTIDASE

(Escherichia
coli)
PF00144
(Beta-lactamase)
5 LEU A 340
ARG A 341
HIS A 279
LEU A 370
GLY A  67
None
1.24A 4l9qA-4e6wA:
undetectable
4l9qA-4e6wA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fys AMINOPEPTIDASE N

(Homo sapiens)
PF01433
(Peptidase_M1)
PF11838
(ERAP1_C)
5 LEU A 390
ALA A 281
ILE A 300
LEU A 338
GLY A 297
None
1.27A 4l9qA-4fysA:
undetectable
4l9qA-4fysA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gg2 GAMMA-GLUTAMYLTRANSP
EPTIDASE 1 HEAVY
CHAIN


(Homo sapiens)
PF01019
(G_glu_transpept)
5 PRO A 159
ALA A  57
TYR A 141
ILE A 138
GLY A  86
None
1.08A 4l9qA-4gg2A:
undetectable
4l9qA-4gg2A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnr ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN-BRANCHED
CHAIN AMINO ACID
TRANSPORT


(Streptococcus
pneumoniae)
PF13458
(Peripla_BP_6)
5 ALA A 120
TYR A 189
ILE A 193
TYR A 238
GLY A 260
None
ILE  A 401 (-4.0A)
None
ILE  A 401 (-4.6A)
None
1.34A 4l9qA-4gnrA:
undetectable
4l9qA-4gnrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gxr MALONYL COA
SYNTHETASE,
BENZOATE-COA LIGASE
CHIMERIC PROTEIN


(Paraburkholderia
xenovorans;
Rhodopseudomonas
palustris)
PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
5 LEU A 175
ALA A 214
TYR A  70
LEU A   5
GLY A  78
None
1.26A 4l9qA-4gxrA:
undetectable
4l9qA-4gxrA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jy4 PGT121 HEAVY CHAIN

(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
5 LEU B  69
ILE B  37
TYR B  90
LEU B  20
GLY B 102
None
1.35A 4l9qA-4jy4B:
undetectable
4l9qA-4jy4B:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0l PREDICTED COMPONENT
OF A
THERMOPHILE-SPECIFIC
DNA REPAIR SYSTEM,
CONTAINS A RAMP
DOMAIN


(Methanopyrus
kandleri)
PF03787
(RAMPs)
5 LEU A 136
PRO A 154
ILE A 128
LEU A 160
GLY A 125
None
1.33A 4l9qA-4n0lA:
undetectable
4l9qA-4n0lA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oen SECOND SUBSTRATE
BINDING DOMAIN OF
PUTATIVE AMINO ACID
ABC TRANSPORTER


(Streptococcus
pneumoniae)
PF00497
(SBP_bac_3)
5 LEU A 357
ILE A 417
TYR A 409
LEU A 437
GLY A 415
None
1.24A 4l9qA-4oenA:
undetectable
4l9qA-4oenA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1c TOLUENE-4-MONOOXYGEN
ASE SYSTEM PROTEIN A


(Pseudomonas
mendocina)
PF02332
(Phenol_Hydrox)
5 LEU A 393
PRO A 403
ALA A 171
ILE A 459
GLY A 457
None
1.37A 4l9qA-4p1cA:
undetectable
4l9qA-4p1cA:
20.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus)
PF00273
(Serum_albumin)
6 PRO A 118
ALA A 126
TYR A 138
HIS A 146
TYR A 161
LEU A 182
None
0.97A 4l9qA-4po0A:
49.8
4l9qA-4po0A:
74.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9t NUCLEOPORIN NUP133

(Vanderwaltozyma
polyspora)
PF08801
(Nucleoporin_N)
5 LEU A 288
ALA A 422
ILE A 286
LEU A 310
GLY A 307
None
1.25A 4l9qA-4q9tA:
undetectable
4l9qA-4q9tA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s12 N-ACETYLMURAMIC ACID
6-PHOSPHATE ETHERASE


(Yersinia
enterocolitica)
PF01380
(SIS)
5 LEU A 129
ALA A 163
LEU A  65
ARG A  64
GLY A  62
None
1.17A 4l9qA-4s12A:
undetectable
4l9qA-4s12A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twi NAD-DEPENDENT
PROTEIN DEACYLASE 1


(Archaeoglobus
fulgidus)
PF02146
(SIR2)
5 LEU A  18
ALA A  79
ILE A 207
LEU A  15
GLY A 205
None
1.27A 4l9qA-4twiA:
undetectable
4l9qA-4twiA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tza FLUORESCENT PROTEIN

(synthetic
construct)
no annotation 5 LEU C  42
ALA C 103
TYR C 116
ILE C  10
GLY C  31
None
None
CRQ  C  62 ( 4.7A)
None
None
1.32A 4l9qA-4tzaC:
undetectable
4l9qA-4tzaC:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um8 INTEGRIN BETA-6

(Homo sapiens)
PF00362
(Integrin_beta)
PF17205
(PSI_integrin)
5 LEU B 121
ALA B 331
ILE B 239
HIS B 195
LEU B 118
None
1.32A 4l9qA-4um8B:
undetectable
4l9qA-4um8B:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uoz BETA-GALACTOSIDASE

(Bifidobacterium
animalis)
PF02449
(Glyco_hydro_42)
PF08532
(Glyco_hydro_42M)
PF08533
(Glyco_hydro_42C)
5 LEU A 538
ALA A 589
TYR A 504
ILE A 439
LEU A 608
None
1.34A 4l9qA-4uozA:
undetectable
4l9qA-4uozA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uym 14-ALPHA STEROL
DEMETHYLASE


(Aspergillus
fumigatus)
PF00067
(p450)
6 LEU A 417
ALA A  81
LYS A  74
TYR A  73
HIS A 370
ARG A 368
None
1.35A 4l9qA-4uymA:
undetectable
4l9qA-4uymA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbt PROBABLE
HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE


(Sinorhizobium
meliloti)
PF00155
(Aminotran_1_2)
5 PRO A 207
ALA A 182
ILE A  94
LEU A 239
GLY A 236
None
None
PLP  A 401 (-3.6A)
None
None
1.25A 4l9qA-4wbtA:
undetectable
4l9qA-4wbtA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrw URACIL-DNA
GLYCOSYLASE


(Mycobacterium
tuberculosis)
PF03167
(UDG)
5 LEU A 226
ARG A 225
ALA A 103
ARG A 121
GLY A 122
None
None
GOL  A 304 ( 3.7A)
None
None
1.19A 4l9qA-4wrwA:
undetectable
4l9qA-4wrwA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa9 GALA PROTEIN TYPE 1,
3 OR 4


(Legionella
pneumophila)
PF13516
(LRR_6)
5 LEU A 122
ALA A 111
ILE A 167
LEU A 149
GLY A 193
None
1.27A 4l9qA-4xa9A:
undetectable
4l9qA-4xa9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0i 4-AMINOBUTYRATE
AMINOTRANSFERASE,
MITOCHONDRIAL


(Sus scrofa)
PF00202
(Aminotran_3)
5 ARG A 222
ALA A 218
ILE A 267
ARG A 406
GLY A 407
None
1.37A 4l9qA-4y0iA:
undetectable
4l9qA-4y0iA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0i 4-AMINOBUTYRATE
AMINOTRANSFERASE,
MITOCHONDRIAL


(Sus scrofa)
PF00202
(Aminotran_3)
5 ARG A 222
ILE A 267
LEU A 223
ARG A 406
GLY A 407
None
1.02A 4l9qA-4y0iA:
undetectable
4l9qA-4y0iA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj1 UNCHARACTERIZED
PROTEIN


(Trypanosoma
brucei)
PF09818
(ABC_ATPase)
5 ALA A 325
ILE A 649
HIS A 648
LEU A 405
GLY A 402
None
1.22A 4l9qA-4yj1A:
undetectable
4l9qA-4yj1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxt POLYKETIDE
BIOSYNTHESIS
3-HYDROXY-3-METHYLGL
UTARYL-ACP SYNTHASE
PKSG


(Bacillus
subtilis)
PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C)
5 LEU A 229
ALA A 260
LYS A 267
TYR A 240
GLY A 237
None
1.06A 4l9qA-4yxtA:
undetectable
4l9qA-4yxtA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z26 PUTATIVE GMC-TYPE
OXIDOREDUCTASE R135


(Acanthamoeba
polyphaga
mimivirus)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
5 ARG A  27
ALA A 232
ILE A 632
LEU A 638
GLY A 634
None
1.20A 4l9qA-4z26A:
undetectable
4l9qA-4z26A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d9a POLYMERASE BASIC
PROTEIN 2
RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT


(Influenza C
virus)
PF00602
(Flu_PB1)
PF00604
(Flu_PB2)
5 PRO B 631
ALA C  71
ILE B 576
ARG B 573
GLY B 572
None
1.35A 4l9qA-5d9aB:
3.6
4l9qA-5d9aB:
21.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
5 ALA A 125
TYR A 137
HIS A 145
TYR A 160
LEU A 181
None
0.35A 4l9qA-5dqfA:
50.5
4l9qA-5dqfA:
76.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f1u 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE


(Campylobacter
jejuni)
PF00701
(DHDPS)
5 LEU A 155
ILE A 126
HIS A 122
LEU A 135
GLY A  82
None
1.26A 4l9qA-5f1uA:
undetectable
4l9qA-5f1uA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f8v AMINOTRANSFERASE,
CLASS V FAMILY
PROTEIN


(Trichomonas
vaginalis)
PF00266
(Aminotran_5)
5 LEU A  62
PRO A 186
ALA A 272
ILE A 257
GLY A 205
None
1.18A 4l9qA-5f8vA:
undetectable
4l9qA-5f8vA:
21.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 ALA A 126
LYS A 137
ILE A 142
HIS A 146
TYR A 161
None
1.00A 4l9qA-5ghkA:
47.3
4l9qA-5ghkA:
79.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 ALA A 126
TYR A 138
ILE A 142
HIS A 146
TYR A 161
None
0.60A 4l9qA-5ghkA:
47.3
4l9qA-5ghkA:
79.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 LYS A 137
ILE A 142
HIS A 146
TYR A 161
ARG A 186
None
0.94A 4l9qA-5ghkA:
47.3
4l9qA-5ghkA:
79.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 TYR A 138
ILE A 142
HIS A 146
TYR A 161
ARG A 186
None
0.77A 4l9qA-5ghkA:
47.3
4l9qA-5ghkA:
79.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5giv CARBOXYPEPTIDASE 1

(Deinococcus
radiodurans)
PF02074
(Peptidase_M32)
5 LEU A 305
ARG A 308
ALA A 315
TYR A 221
LEU A 265
None
1.08A 4l9qA-5givA:
1.7
4l9qA-5givA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt1 CHOLINE BINDING
PROTEIN A


(Lactobacillus
salivarius)
PF01551
(Peptidase_M23)
5 PRO A 368
ILE A 478
TYR A 442
LEU A 474
GLY A 397
None
1.27A 4l9qA-5gt1A:
undetectable
4l9qA-5gt1A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idu ACYL-COA
DEHYDROGENASE DOMAIN
PROTEIN


(Paraburkholderia
phymatum)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
5 LEU A 112
ALA A 134
ILE A  77
LEU A 123
GLY A  74
None
1.14A 4l9qA-5iduA:
2.3
4l9qA-5iduA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikg DYE-DECOLORIZING
PEROXIDASE


(Auricularia
auricula-judae)
PF04261
(Dyp_perox)
5 ARG A 217
ALA A 151
ILE A 114
TYR A 147
GLY A 111
None
1.35A 4l9qA-5ikgA:
undetectable
4l9qA-5ikgA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jsc PUTATIVE ACYL-COA
DEHYDROGENASE


(Paraburkholderia
xenovorans)
PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N)
5 LEU A 113
ALA A 135
ILE A  78
LEU A 124
GLY A  75
None
1.25A 4l9qA-5jscA:
2.3
4l9qA-5jscA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktl 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE


(Trichormus
variabilis)
PF00701
(DHDPS)
5 LEU A 154
ILE A 124
HIS A 120
LEU A 134
GLY A  80
None
None
None
KPI  A 164 ( 4.8A)
None
1.28A 4l9qA-5ktlA:
undetectable
4l9qA-5ktlA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lk7 VP1

(Slow bee
paralysis virus)
PF08762
(CRPV_capsid)
5 TYR A 221
ILE A  91
TYR A  43
LEU A  72
GLY A  89
None
1.14A 4l9qA-5lk7A:
undetectable
4l9qA-5lk7A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lrb ALPHA-1,4 GLUCAN
PHOSPHORYLASE


(Hordeum vulgare)
PF00343
(Phosphorylase)
5 LEU A 480
ARG A 569
ALA A 490
ILE A 450
GLY A 577
None
1.27A 4l9qA-5lrbA:
undetectable
4l9qA-5lrbA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL


(Photorhabdus
asymbiotica)
PF03984
(DUF346)
5 ALA A 276
ILE A  32
LEU A 294
ARG A 288
GLY A 337
None
None
None
None
MFU  A 401 (-3.2A)
1.27A 4l9qA-5mxfA:
undetectable
4l9qA-5mxfA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfq EPOXIDE HYDROLASE
BELONGING TO
ALPHA/BETA HYDROLASE
SUPERFAMILY
METAGENOMIC FROM
TOMSK SAMPLE


(metagenome)
no annotation 5 LEU A 237
PRO A 266
ILE A  98
LEU A 242
GLY A 100
None
1.26A 4l9qA-5nfqA:
undetectable
4l9qA-5nfqA:
8.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 5 LYS A 136
TYR A 137
HIS A 145
TYR A 160
ARG A 185
None
1.13A 4l9qA-5oriA:
50.8
4l9qA-5oriA:
74.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t9c GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE


(Bacillus
subtilis)
PF03009
(GDPD)
5 LEU E  32
ALA E  61
TYR E 150
ILE E 186
GLY E 233
None
1.17A 4l9qA-5t9cE:
undetectable
4l9qA-5t9cE:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vys GDP-MANNOSE
4,6-DEHYDRATASE /
GDP-4-AMINO-4,6-DIDE
OXY-D-MANNOSE
FORMYLTRANSFERASE


(Brucella
melitensis)
PF00551
(Formyl_trans_N)
5 PRO A 228
ILE A 169
HIS A  86
ARG A  45
GLY A  15
None
None
None
GDP  A 303 (-2.6A)
None
1.33A 4l9qA-5vysA:
undetectable
4l9qA-5vysA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wug BETA-GLUCOSIDASE

(Paenibacillus
barengoltzii)
no annotation 5 ALA A 451
TYR A 695
ILE A 627
ARG A 288
GLY A 286
None
1.15A 4l9qA-5wugA:
undetectable
4l9qA-5wugA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ysb LIN1841 PROTEIN

(Listeria
innocua)
no annotation 5 LEU A 289
PRO A 167
ALA A 177
TYR A 231
GLY A 208
None
None
None
None
ZN  A 508 ( 4.7A)
1.00A 4l9qA-5ysbA:
undetectable
4l9qA-5ysbA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 6 LEU A 115
PRO A 118
ALA A 126
TYR A 138
HIS A 146
TYR A 161
None
0.90A 4l9qA-5yxeA:
45.7
4l9qA-5yxeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 6 PRO A 118
ALA A 126
TYR A 138
ILE A 142
HIS A 146
TYR A 161
None
0.47A 4l9qA-5yxeA:
45.7
4l9qA-5yxeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ehs HYDROGENASE-2 LARGE
CHAIN


(Escherichia
coli)
no annotation 5 LEU L 235
ARG L 239
ALA L  98
TYR L 443
ILE L 447
None
1.30A 4l9qA-6ehsL:
0.7
4l9qA-6ehsL:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1


(Saccharomyces
cerevisiae)
no annotation 5 PRO A 932
ALA A1000
TYR A 916
ILE A1089
GLY A1093
None
1.13A 4l9qA-6f42A:
2.3
4l9qA-6f42A:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g3u -

(-)
no annotation 5 PRO A 115
ALA A 125
ILE A 265
HIS A 269
GLY A 453
None
1.06A 4l9qA-6g3uA:
3.2
4l9qA-6g3uA:
undetectable