SIMILAR PATTERNS OF AMINO ACIDS FOR 4L7I_B_SAMB501_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c4k | PROTEIN (ORNITHINEDECARBOXYLASE) (Lactobacillussp. 30A) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 5 | ASN A 222ARG A 220ASP A 258LEU A 241ILE A 306 | None | 1.10A | 4l7iA-1c4kA:0.0 | 4l7iA-1c4kA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c6v | PROTEIN (SIVINTEGRASE) (Simianimmunodeficiencyvirus) |
PF00665(rve) | 4 | HIS A 156ASN A 160ASP A 163ILE A 162 | None | 1.05A | 4l7iA-1c6vA:0.0 | 4l7iA-1c6vA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dbv | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Geobacillusstearothermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 152LEU O 324ASN O 146ILE O 144 | None | 1.04A | 4l7iA-1dbvO:0.0 | 4l7iA-1dbvO:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f02 | INTIMINTRANSLOCATED INTIMINRECEPTOR (Escherichiacoli;Escherichiacoli) |
PF02368(Big_2)PF02369(Big_1)PF07979(Intimin_C)PF03549(Tir_receptor_M) | 4 | ASP T 302ASN I 921ASP I 916ILE I 897 | None | 1.07A | 4l7iA-1f02T:undetectable | 4l7iA-1f02T:10.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1foh | PHENOL HYDROXYLASE (Cutaneotrichosporoncutaneum) |
PF01494(FAD_binding_3)PF07976(Phe_hydrox_dim) | 4 | ASN A 78ARG A 281ASP A 102ILE A 83 | None | 0.77A | 4l7iA-1fohA:0.0 | 4l7iA-1fohA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g2p | ADENINEPHOSPHORIBOSYLTRANSFERASE 1 (Saccharomycescerevisiae) |
PF00156(Pribosyltran) | 4 | HIS A 50LEU A 51ASN A 156ILE A 63 | None | 1.00A | 4l7iA-1g2pA:0.0 | 4l7iA-1g2pA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h3g | CYCLOMALTODEXTRINASE (Flavobacteriumsp. 92) |
PF00128(Alpha-amylase)PF09087(Cyc-maltodext_N)PF10438(Cyc-maltodext_C) | 4 | ASN A 409ARG A 445ASN A 336ILE A 216 | None | 1.03A | 4l7iA-1h3gA:0.0 | 4l7iA-1h3gA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iho | PANTOATE--BETA-ALANINE LIGASE (Escherichiacoli) |
PF02569(Pantoate_ligase) | 4 | ARG A 73ASP A 78LEU A 75ILE A 3 | None | 1.02A | 4l7iA-1ihoA:0.0 | 4l7iA-1ihoA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1js4 | ENDO/EXOCELLULASE E4 (Thermobifidafusca) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 4 | LEU A 178ASN A 101ASP A 102ILE A 105 | None | 1.06A | 4l7iA-1js4A:0.0 | 4l7iA-1js4A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ny1 | PROBABLEPOLYSACCHARIDEDEACETYLASE PDAA (Bacillussubtilis) |
PF01522(Polysacc_deac_1) | 4 | ASP A 251ASN A 159ASP A 158ILE A 120 | None | 0.95A | 4l7iA-1ny1A:undetectable | 4l7iA-1ny1A:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tj5 | SUCROSE-PHOSPHATASE (Synechocystissp. PCC 6803) |
PF05116(S6PP) | 4 | ARG A 43ASP A 190ASP A 155ILE A 147 | SUC A 245 (-4.9A) MG A 247 (-2.9A)SUC A 245 (-2.8A)None | 1.06A | 4l7iA-1tj5A:undetectable | 4l7iA-1tj5A:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6y | ADP-RIBOSYLATIONFACTOR-LIKE PROTEIN5 (Homo sapiens) |
PF00025(Arf) | 4 | HIS A 150ASP A 114LEU A 115ILE A 20 | None | 1.02A | 4l7iA-1z6yA:undetectable | 4l7iA-1z6yA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zup | HYPOTHETICAL PROTEINTM1739 (Thermotogamaritima) |
PF09376(NurA) | 4 | ARG A 232ASP A 157LEU A 175ILE A 273 | None | 1.06A | 4l7iA-1zupA:undetectable | 4l7iA-1zupA:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bz0 | GTP CYCLOHYDROLASEII (Escherichiacoli) |
PF00925(GTP_cyclohydro2) | 4 | HIS A 89ASN A 95ASP A 135LEU A 132 | None | 1.04A | 4l7iA-2bz0A:undetectable | 4l7iA-2bz0A:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3o | PYRUVATE-FERREDOXINOXIDOREDUCTASE (Desulfovibrioafricanus) |
PF01558(POR)PF01855(POR_N)PF02775(TPP_enzyme_C)PF10371(EKR)PF13484(Fer4_16)PF17147(PFOR_II) | 4 | HIS A 16ASP A 190LEU A 186ASP A 151 | None | 1.04A | 4l7iA-2c3oA:undetectable | 4l7iA-2c3oA:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ep7 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Aquifexaeolicus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 155LEU A 333ASN A 149ILE A 147 | None | 1.00A | 4l7iA-2ep7A:undetectable | 4l7iA-2ep7A:23.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jtc | STREPTOPAIN (Streptococcuspyogenes) |
PF01640(Peptidase_C10) | 4 | ASP A 175LEU A 178ASP A 200ILE A 199 | None | 1.06A | 4l7iA-2jtcA:undetectable | 4l7iA-2jtcA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nq3 | ITCHY HOMOLOG E3UBIQUITIN PROTEINLIGASE (Homo sapiens) |
PF00168(C2) | 4 | HIS A 80ASP A 48ASP A 101ILE A 102 | None | 1.06A | 4l7iA-2nq3A:undetectable | 4l7iA-2nq3A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qma | DIAMINOBUTYRATE-PYRUVATE TRANSAMINASEANDL-2,4-DIAMINOBUTYRATE DECARBOXYLASE (Vibrioparahaemolyticus) |
PF00282(Pyridoxal_deC) | 4 | HIS A 859ASP A 942LEU A 938ILE A 565 | None | 1.06A | 4l7iA-2qmaA:undetectable | 4l7iA-2qmaA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2tmk | THYMIDYLATE KINASE (Saccharomycescerevisiae) |
PF02223(Thymidylate_kin) | 4 | ASN A 32LEU A 204ASN A 89ILE A 8 | None | 0.98A | 4l7iA-2tmkA:undetectable | 4l7iA-2tmkA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxr | BOTULINUM NEUROTOXINTYPE G (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 4 | ASN A1001ARG A1132ASN A1141ILE A1140 | None | 0.88A | 4l7iA-2vxrA:undetectable | 4l7iA-2vxrA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 4 | ASN A 328ASP A 301ASN A 356ILE A 322 | None | 0.98A | 4l7iA-2vz9A:undetectable | 4l7iA-2vz9A:10.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xr1 | CLEAVAGE ANDPOLYADENYLATIONSPECIFICITY FACTOR100 KD SUBUNIT (Methanosarcinamazei) |
PF07521(RMMBL)PF07650(KH_2)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | HIS A 12ASP A 5LEU A 8ASP A 26 | None | 0.96A | 4l7iA-2xr1A:undetectable | 4l7iA-2xr1A:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a9g | PUTATIVEUNCHARACTERIZEDPROTEIN (Pyrobaculumaerophilum) |
PF07995(GSDH) | 4 | ASN A 122ARG A 121ASN A 153ILE A 151 | None | 0.96A | 4l7iA-3a9gA:undetectable | 4l7iA-3a9gA:24.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b05 | ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE (Sulfolobusshibatae) |
PF01070(FMN_dh) | 4 | HIS A 155ARG A 98ASN A 125ILE A 152 | IPE A 701 ( 3.4A)IPE A 701 (-3.9A)FNR A 669 (-3.0A)None | 1.01A | 4l7iA-3b05A:undetectable | 4l7iA-3b05A:23.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8a | HEXOKINASE-1 (Saccharomycescerevisiae) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 4 | ASN X 237ASP X 86ASN X 210ILE X 209 | BGC X 501 (-3.8A)NoneBGC X 501 (-3.2A)None | 0.87A | 4l7iA-3b8aX:undetectable | 4l7iA-3b8aX:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgd | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE,CLASS I (Bacillusanthracis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | ASN A 62ARG A 61ASP A 9ILE A 135 | NoneCOA A 445 (-2.9A)FAD A 446 ( 3.5A)None | 1.07A | 4l7iA-3cgdA:undetectable | 4l7iA-3cgdA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqn | GLUCAN1,3-BETA-GLUCOSIDASE (Phanerochaetechrysosporium) |
PF12708(Pectate_lyase_3) | 5 | HIS A 576ASN A 147ASP A 579LEU A 578ILE A 525 | ZN A 758 (-3.2A)GOL A 766 ( 3.7A)NoneNoneNone | 1.44A | 4l7iA-3eqnA:undetectable | 4l7iA-3eqnA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ewk | SENSOR PROTEIN (Methylococcuscapsulatus) |
PF13426(PAS_9) | 4 | ASN A 286ARG A 288LEU A 238ILE A 231 | None | 1.01A | 4l7iA-3ewkA:undetectable | 4l7iA-3ewkA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g6i | PUTATIVE OUTERMEMBRANE PROTEIN,PART OF CARBOHYDRATEBINDING COMPLEX (Bacteroidesthetaiotaomicron) |
PF12875(DUF3826) | 4 | HIS A 112ASP A 105LEU A 108ILE A 72 | None | 1.08A | 4l7iA-3g6iA:undetectable | 4l7iA-3g6iA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i9v | NADH-QUINONEOXIDOREDUCTASESUBUNIT 3NADH-QUINONEOXIDOREDUCTASESUBUNIT 4NADH-QUINONEOXIDOREDUCTASESUBUNIT 5 (Thermusthermophilus;Thermusthermophilus;Thermusthermophilus) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4)PF10588(NADH-G_4Fe-4S_3)PF13510(Fer2_4)PF00346(Complex1_49kDa)PF00329(Complex1_30kDa) | 4 | HIS 4 336ASP 5 178LEU 5 174ASP 3 132 | None | 1.04A | 4l7iA-3i9v4:undetectable | 4l7iA-3i9v4:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4w | UNCHARACTERIZEDPROTEIN BB4693 (Bordetellabronchiseptica) |
PF04909(Amidohydro_2) | 4 | ASN A 68ARG A 67ASN A 77ILE A 117 | None | 1.04A | 4l7iA-3k4wA:undetectable | 4l7iA-3k4wA:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6d | PUTATIVEOXIDOREDUCTASE (Pseudomonasputida) |
PF03446(NAD_binding_2) | 5 | HIS A 80ASN A 76LEU A 83ASP A 99ILE A 97 | None | 1.49A | 4l7iA-3l6dA:undetectable | 4l7iA-3l6dA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lae | UPF0053 PROTEINHI0107 (Haemophilusinfluenzae) |
PF03471(CorC_HlyC) | 4 | ASN A 20ARG A 17ASP A 56ILE A 55 | NonePO4 A 79 (-4.0A)NoneNone | 0.96A | 4l7iA-3laeA:undetectable | 4l7iA-3laeA:14.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mpp | BOTULINUM NEUROTOXINTYPE G (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 4 | ASN G1001ARG G1132ASN G1141ILE G1140 | None | 0.84A | 4l7iA-3mppG:undetectable | 4l7iA-3mppG:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mue | PANTOTHENATESYNTHETASE (Salmonellaenterica) |
PF02569(Pantoate_ligase) | 4 | ARG A 73ASP A 78LEU A 75ILE A 3 | None | 0.99A | 4l7iA-3mueA:undetectable | 4l7iA-3mueA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2x | UNCHARACTERIZEDPROTEIN YAGE (Escherichiacoli) |
PF00701(DHDPS) | 4 | HIS A 78ASP A 42ASP A 32ILE A 24 | None | 0.92A | 4l7iA-3n2xA:undetectable | 4l7iA-3n2xA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqx | SECRETEDMETALLOPROTEASEMCP02 (Pseudoalteromonassp. SM9913) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C) | 4 | HIS A 282ASN A 241ASN A 286ILE A 288 | None | 0.91A | 4l7iA-3nqxA:undetectable | 4l7iA-3nqxA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3poh | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE F1 (Bacteroidesthetaiotaomicron) |
PF08522(DUF1735) | 4 | LEU A 77ASN A 46ASP A 162ILE A 163 | None | 0.93A | 4l7iA-3pohA:undetectable | 4l7iA-3pohA:23.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tsy | FUSION PROTEIN4-COUMARATE--COALIGASE 1,RESVERATROL SYNTHASE (Arabidopsisthaliana;Vitis vinifera) |
PF00195(Chal_sti_synt_N)PF00501(AMP-binding)PF02797(Chal_sti_synt_C)PF13193(AMP-binding_C) | 4 | ASP A 45ASN A 427ASP A 469ILE A 468 | None | 0.95A | 4l7iA-3tsyA:undetectable | 4l7iA-3tsyA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u7v | BETA-GALACTOSIDASE (Caulobactervibrioides) |
PF02449(Glyco_hydro_42) | 4 | ASN A 381ASP A 390ASN A 350ASP A 351 | None | 1.02A | 4l7iA-3u7vA:undetectable | 4l7iA-3u7vA:22.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujz | METALLOPROTEASE STCE (Escherichiacoli) |
PF10462(Peptidase_M66) | 4 | ASN A 868ASP A 109ASN A 870ASP A 873 | None | 1.03A | 4l7iA-3ujzA:undetectable | 4l7iA-3ujzA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uma | HYPOTHETICALPEROXIREDOXINPROTEIN (Sinorhizobiummeliloti) |
PF08534(Redoxin) | 4 | ASP A 62LEU A 65ASP A 71ILE A 72 | None | 0.93A | 4l7iA-3umaA:undetectable | 4l7iA-3umaA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ziz | GH5ENDO-BETA-1,4-MANNANASE (Podosporaanserina) |
PF00150(Cellulase) | 4 | ASN A 87ARG A 91ASN A 83ILE A 82 | None | 0.84A | 4l7iA-3zizA:undetectable | 4l7iA-3zizA:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuv | DESIGNED ANKYRINREPEAT PROTEIN (syntheticconstruct) |
PF13857(Ank_5) | 4 | ARG B 23ASP B 46LEU B 48ILE B 81 | None | 0.98A | 4l7iA-3zuvB:undetectable | 4l7iA-3zuvB:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a26 | PUTATIVEC-1-TETRAHYDROFOLATESYNTHASE,CYTOPLASMIC (Leishmaniamajor) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | ASN A 110ASP A 123LEU A 125ILE A 174 | None | 1.05A | 4l7iA-4a26A:undetectable | 4l7iA-4a26A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2l | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSE (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 5 | ASN A 383ARG A 388LEU A 381ASN A 369ASP A 367 | None | 1.33A | 4l7iA-4a2lA:undetectable | 4l7iA-4a2lA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | ASN A 259ASN A 253ASP A 254ILE A 33 | None | 0.91A | 4l7iA-4bedA:undetectable | 4l7iA-4bedA:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bgv | MALATE DEHYDROGENASE (Picrophilustorridus) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | ASN A 323ASP A 96LEU A 99ASP A 318ILE A 315 | None | 1.36A | 4l7iA-4bgvA:undetectable | 4l7iA-4bgvA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwi | PHYTOCHROME-LIKEPROTEIN CPH2 (Synechocystissp.) |
PF00360(PHY)PF01590(GAF) | 4 | ASN A 90ARG A 92LEU A 153ILE A 80 | GLU A1427 (-3.2A)NoneGLU A1427 ( 4.9A)CYC A1422 (-4.0A) | 1.09A | 4l7iA-4bwiA:undetectable | 4l7iA-4bwiA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwy | P4 (Pseudomonasphage phi8) |
PF11602(NTPase_P4) | 4 | HIS A 239ASP A 265LEU A 262ILE A 260 | None | 0.92A | 4l7iA-4bwyA:undetectable | 4l7iA-4bwyA:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bx9 | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 33A (Homo sapiens) |
PF00995(Sec1) | 4 | ASP A 39LEU A 66ASN A 96ILE A 93 | None | 1.09A | 4l7iA-4bx9A:undetectable | 4l7iA-4bx9A:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ft2 | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Zea mays) |
PF00145(DNA_methylase)PF00385(Chromo)PF01426(BAH) | 4 | ASN A 670ARG A 819LEU A 720ASP A 726 | None | 1.08A | 4l7iA-4ft2A:undetectable | 4l7iA-4ft2A:18.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ged | ASCORBATE PEROXIDASE (Leishmaniamajor) |
PF00141(peroxidase) | 4 | HIS A 68ASN A 98ASP A 163ASP A 158 | None | 1.07A | 4l7iA-4gedA:undetectable | 4l7iA-4gedA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gib | BETA-PHOSPHOGLUCOMUTASE (Clostridioidesdifficile) |
PF13419(HAD_2) | 4 | ASN A 78ASP A 138ASN A 119ILE A 121 | NoneNonePO4 A 304 (-3.8A)None | 1.06A | 4l7iA-4gibA:undetectable | 4l7iA-4gibA:22.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hpv | S-ADENOSYLMETHIONINESYNTHASE (Sulfolobussolfataricus) |
PF01941(AdoMet_Synthase) | 4 | ASN A 60ASN A 159ASP A 160ILE A 349 | None | 0.81A | 4l7iA-4hpvA:63.6 | 4l7iA-4hpvA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jso | OLIGOPEPTIDE ABCTRANSPORTER,PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Thermotogamaritima) |
PF00496(SBP_bac_5) | 4 | ASN A 270ASP A 466ASP A 498ILE A 494 | None | 0.91A | 4l7iA-4jsoA:undetectable | 4l7iA-4jsoA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kca | ENDO-1,5-ALPHA-L-ARABINANASE (Bos taurus) |
PF00085(Thioredoxin)PF04616(Glyco_hydro_43)PF16369(GH43_C) | 4 | HIS A 6ASP A 26ASP A 61ILE A 60 | None | 0.87A | 4l7iA-4kcaA:undetectable | 4l7iA-4kcaA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | ARYLPHORIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | ASN B 349ARG B 244ASN B 353ASP B 360 | None | 1.03A | 4l7iA-4l37B:undetectable | 4l7iA-4l37B:18.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4l4q | S-ADENOSYLMETHIONINESYNTHASE (Thermococcuskodakarensis) |
PF01941(AdoMet_Synthase) | 4 | HIS A 62ARG A 95ASP A 162ASN A 312 | None | 1.01A | 4l7iA-4l4qA:55.8 | 4l7iA-4l4qA:51.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nx8 | PROTEIN-TYROSINEPHOSPHATASE 2 (Bdellovibriobacteriovorus) |
PF14566(PTPlike_phytase) | 4 | ARG A 137ASP A 146LEU A 142ILE A 108 | None | 1.07A | 4l7iA-4nx8A:undetectable | 4l7iA-4nx8A:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9x | TCDB2, TCCC3 (Photorhabdusluminescens) |
PF03534(SpvB)PF12255(TcdB_toxin_midC)PF12256(TcdB_toxin_midN) | 4 | ARG A 892ASN A 853ASP A 852ILE A 851 | None | 0.95A | 4l7iA-4o9xA:undetectable | 4l7iA-4o9xA:11.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p1b | TOLUENE-4-MONOOXYGENASE SYSTEMFERREDOXIN SUBUNIT (Pseudomonasmendocina) |
PF00355(Rieske) | 4 | ASP H 96LEU H 9ASN H 32ILE H 98 | None | 1.07A | 4l7iA-4p1bH:undetectable | 4l7iA-4p1bH:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4phc | HISTIDINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF03129(HGTP_anticodon)PF13393(tRNA-synt_His) | 4 | ASP A 218LEU A 217ASN A 212ILE A 335 | None | 1.08A | 4l7iA-4phcA:undetectable | 4l7iA-4phcA:23.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4plb | CHIMERA PROTEIN OFDNA GYRASE SUBUNITSB AND A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV)PF00986(DNA_gyraseB_C)PF01751(Toprim) | 4 | ASN B1054ASP B1040LEU B1160ILE B1144 | None | 1.00A | 4l7iA-4plbB:undetectable | 4l7iA-4plbB:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfk | ABC TRANSPORTERPERIPLASMICPEPTIDE-BINDINGPROTEIN (Pseudoalteromonassp. SM9913) |
no annotation | 4 | ARG H 390LEU H 430ASN H 386ILE H 503 | None | 0.75A | 4l7iA-4qfkH:undetectable | 4l7iA-4qfkH:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qnx | TRNA(MO5U34)-METHYLTRANSFERASE (Escherichiacoli) |
PF08003(Methyltransf_9) | 4 | HIS A 146ARG A 173LEU A 147ILE A 11 | None | 0.91A | 4l7iA-4qnxA:undetectable | 4l7iA-4qnxA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qr8 | XAA-PRO DIPEPTIDASE (Escherichiacoli) |
PF00557(Peptidase_M24) | 4 | ASN A 435ASP A 279LEU A 282ILE A 422 | None | 1.08A | 4l7iA-4qr8A:undetectable | 4l7iA-4qr8A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3a | BLUE-LIGHT-ACTIVATEDHISTIDINE KINASE 2 (Erythrobacterlitoralis) |
PF07568(HisKA_2)PF13426(PAS_9)PF13581(HATPase_c_2) | 4 | HIS A 147ARG A 175LEU A 148ILE A 117 | NoneANP A 401 (-3.6A)NoneNone | 1.06A | 4l7iA-4r3aA:undetectable | 4l7iA-4r3aA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk0 | LACI FAMILYSUGAR-BINDINGTRANSCRIPTIONALREGULATOR (Enterococcusfaecalis) |
PF13377(Peripla_BP_3) | 4 | ASN A 81LEU A 224ASN A 248ILE A 247 | RIB A 401 (-3.3A)NoneRIB A 401 (-3.8A)None | 0.94A | 4l7iA-4rk0A:undetectable | 4l7iA-4rk0A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u7t | DNA(CYTOSINE-5)-METHYLTRANSFERASE 3A (Homo sapiens) |
PF00145(DNA_methylase) | 4 | HIS A 677ARG A 676ASP A 652LEU A 648 | None | 0.92A | 4l7iA-4u7tA:undetectable | 4l7iA-4u7tA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ze8 | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN(AGROCINOPINES A ANDB) (Agrobacteriumfabrum) |
PF00496(SBP_bac_5) | 4 | ARG A 32LEU A 518ASP A 256ILE A 257 | SO4 A 601 (-4.1A)NoneNoneNone | 1.08A | 4l7iA-4ze8A:undetectable | 4l7iA-4ze8A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxl | O-GLCNACASE NAGJ (Clostridiumperfringens) |
PF02838(Glyco_hydro_20b)PF07555(NAGidase) | 4 | ASN A 172ASP A 117LEU A 120ILE A 105 | None CD A 706 ( 2.4A)NoneNone | 1.08A | 4l7iA-4zxlA:undetectable | 4l7iA-4zxlA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a22 | VESICULAR STOMATITISVIRUS L POLYMERASE (Vesicularstomatitisvirus) |
PF00946(Mononeg_RNA_pol)PF14314(Methyltrans_Mon)PF14318(Mononeg_mRNAcap) | 4 | ASN A 744ASP A 764ASN A 602ILE A 604 | None | 0.80A | 4l7iA-5a22A:undetectable | 4l7iA-5a22A:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4j | FORMATE--TETRAHYDROFOLATE LIGASE (Tepidanaerobacteracetatoxydans) |
PF01268(FTHFS) | 4 | HIS A 365ASN A 361ARG A 505ASN A 65 | None | 1.02A | 4l7iA-5a4jA:undetectable | 4l7iA-5a4jA:25.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNIT DELTA (Schizosaccharomycespombe) |
PF01008(IF-2B) | 5 | HIS G 276LEU G 313ASN G 281ASP G 282ILE G 285 | None | 1.30A | 4l7iA-5b04G:undetectable | 4l7iA-5b04G:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cdn | DNA GYRASE SUBUNIT A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV) | 4 | ASN A 54ASP A 40LEU A 160ILE A 144 | ASN A 54 ( 0.6A)ASP A 40 ( 0.5A)LEU A 160 ( 0.6A)ILE A 144 ( 0.4A) | 0.99A | 4l7iA-5cdnA:undetectable | 4l7iA-5cdnA:23.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d7w | SERRALYSIN (Serratiamarcescens) |
PF00353(HemolysinCabind)PF00413(Peptidase_M10)PF08548(Peptidase_M10_C) | 4 | ASN A 226ARG A 209ASP A 238LEU A 235 | ASN A 226 ( 0.6A)ARG A 209 ( 0.6A)ASP A 238 ( 0.5A)LEU A 235 ( 0.6A) | 1.07A | 4l7iA-5d7wA:undetectable | 4l7iA-5d7wA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eaw | DNA REPLICATIONATP-DEPENDENTHELICASE/NUCLEASEDNA2 (Mus musculus) |
PF08696(Dna2)PF13086(AAA_11)PF13087(AAA_12) | 4 | ASN A1003ARG A1000ASP A 969ILE A 941 | None | 1.02A | 4l7iA-5eawA:undetectable | 4l7iA-5eawA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gmh | TOLL-LIKE RECEPTOR 7 (Macaca mulatta) |
PF00560(LRR_1)PF13306(LRR_5)PF13855(LRR_8) | 4 | ARG A 296LEU A 256ASN A 300ILE A 281 | None | 1.09A | 4l7iA-5gmhA:undetectable | 4l7iA-5gmhA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnd | PUTATIVE SERINEPROTEASE HHOA (Synechocystissp. PCC 6803) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 4 | ASN A 193ARG A 141LEU A 140ILE A 164 | None | 1.07A | 4l7iA-5gndA:undetectable | 4l7iA-5gndA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1s | 50S RIBOSOMALPROTEIN L13,CHLOROPLASTIC (Spinaciaoleracea) |
PF00572(Ribosomal_L13) | 4 | HIS L 134ARG L 242ASP L 238ILE L 237 | None | 0.91A | 4l7iA-5h1sL:undetectable | 4l7iA-5h1sL:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i70 | PLASMEPSIN IV (Plasmodiumfalciparum) |
no annotation | 4 | ASN B 188ASP B 214ASN B 210ILE B 294 | None | 1.06A | 4l7iA-5i70B:undetectable | 4l7iA-5i70B:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ir2 | CELLULASE (Parabacteroidesjohnsonii) |
PF03737(RraA-like) | 4 | HIS A 109ASP A 34ASP A 193ILE A 194 | None | 0.76A | 4l7iA-5ir2A:undetectable | 4l7iA-5ir2A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbe | INACTIVEGLUCANSUCRASE (Lactobacillusreuteri) |
PF02324(Glyco_hydro_70) | 4 | ARG A1133ASP A1138LEU A1134ASP A1165 | None | 1.04A | 4l7iA-5jbeA:undetectable | 4l7iA-5jbeA:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jod | PROPLASMEPSIN IV (Plasmodiumfalciparum) |
PF00026(Asp) | 4 | ASN A 188ASP A 214ASN A 210ILE A 294 | None | 1.02A | 4l7iA-5jodA:undetectable | 4l7iA-5jodA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kds | F5/8 TYPE C DOMAINPROTEIN (Clostridiumperfringens) |
PF13402(Peptidase_M60) | 4 | ASP A 980ASN A 937ASP A 974ILE A 938 | None | 0.91A | 4l7iA-5kdsA:undetectable | 4l7iA-5kdsA:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kyo | CYP101J2 (Sphingobiumyanoikuyae) |
PF00067(p450) | 4 | ARG A 341ASP A 285LEU A 342ILE A 276 | None | 0.93A | 4l7iA-5kyoA:undetectable | 4l7iA-5kyoA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l5n | PLEXIN-A4 (Mus musculus) |
PF01403(Sema)PF01437(PSI)PF01833(TIG) | 4 | ASN A 792LEU A 721ASN A 796ILE A 709 | ASN A 792 ( 0.6A)LEU A 721 ( 0.6A)ASN A 796 ( 0.6A)ILE A 709 ( 0.6A) | 0.89A | 4l7iA-5l5nA:undetectable | 4l7iA-5l5nA:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ldr | BETA-D-GALACTOSIDASE (Paracoccus sp.32d) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N) | 4 | HIS B 280ARG B 284LEU B 655ILE B 712 | None | 1.08A | 4l7iA-5ldrB:undetectable | 4l7iA-5ldrB:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t8u | LIPOATE-PROTEINLIGASE 1 (Plasmodiumfalciparum) |
PF03099(BPL_LplA_LipB)PF10437(Lip_prot_lig_C) | 4 | ASN A 218LEU A 214ASN A 213ILE A 212 | None | 1.01A | 4l7iA-5t8uA:undetectable | 4l7iA-5t8uA:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vk2 | PRE-GLYCOPROTEINPOLYPROTEIN GPCOMPLEXPRE-GLYCOPROTEINPOLYPROTEIN GPCOMPLEX (Lassamammarenavirus;Lassamammarenavirus) |
PF00798(Arena_glycoprot)PF00798(Arena_glycoprot) | 4 | ARG A 248ASN a 342ASP a 347ILE a 345 | None | 0.99A | 4l7iA-5vk2A:undetectable | 4l7iA-5vk2A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w81 | CYSTIC FIBROSISTRANSMEMBRANECONDUCTANCEREGULATOR (Danio rerio) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF14396(CFTR_R) | 4 | ASN A 188ARG A 154LEU A 157ILE A 369 | None | 0.95A | 4l7iA-5w81A:undetectable | 4l7iA-5w81A:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wt4 | CYSTEINE DESULFURASEISCS (Helicobacterpylori) |
no annotation | 4 | ASN A 9LEU A 7ASN A 361ILE A 366 | None | 1.06A | 4l7iA-5wt4A:undetectable | 4l7iA-5wt4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xks | THERMOSTABLEMONOACYLGLYCEROLLIPASE (Geobacillus sp.12AMOR1) |
no annotation | 5 | ARG A 220ASP A 233LEU A 221ASN A 120ILE A 119 | None | 1.46A | 4l7iA-5xksA:undetectable | 4l7iA-5xksA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn8 | GLYCEROLDEHYDROGENASE (unidentified) |
PF00465(Fe-ADH) | 4 | ARG A 218LEU A 165ASN A 237ILE A 234 | None | 1.04A | 4l7iA-5xn8A:undetectable | 4l7iA-5xn8A:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xqo | PCRGLX PROTEIN (Penicilliumchrysogenum) |
no annotation | 4 | HIS A 565ASN A 902ASP A 642ILE A 649 | NoneRAM A1003 ( 4.1A)NoneNone | 0.83A | 4l7iA-5xqoA:undetectable | 4l7iA-5xqoA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ybb | RESTRICTIONENDONUCLEASE SSUBUNITS (Caldanaerobactersubterraneus) |
no annotation | 4 | ASN D 110ARG D 111LEU D 119ILE D 155 | None | 1.08A | 4l7iA-5ybbD:undetectable | 4l7iA-5ybbD:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6es4 | SYNCRIP, ISOFORM K (Drosophilamelanogaster) |
no annotation | 4 | ASN A 204ARG A 146LEU A 180ILE A 230 | None | 1.09A | 4l7iA-6es4A:undetectable | 4l7iA-6es4A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f9c | GLYCOPROTEIN (Rift Valleyfeverphlebovirus) |
no annotation | 4 | ASP A 370LEU A 368ASN A 366ILE A 442 | None | 0.87A | 4l7iA-6f9cA:undetectable | 4l7iA-6f9cA:undetectable |