SIMILAR PATTERNS OF AMINO ACIDS FOR 4L78_A_ACTA1327_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a5j B-MYB

(Gallus gallus) 		PF00249
(Myb_DNA-binding) 		4 VAL A  57
THR A  63
GLU A  64
GLU A  65
 None
 1.40A 4l78A-1a5jA:
undetectable		 4l78A-1a5jA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c2r CYTOCHROME C2

(Rhodobacter
capsulatus) 		no annotation 4 VAL A  41
THR A  68
GLU A  69
GLU A  70
 None
 1.12A 4l78A-1c2rA:
undetectable		 4l78A-1c2rA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1erz N-CARBAMYL-D-AMINO
ACID AMIDOHYDROLASE

(Agrobacterium
sp. KNK712) 		PF00795
(CN_hydrolase) 		4 VAL A  99
THR A  70
GLU A  97
GLU A  69
 None
 1.19A 4l78A-1erzA:
0.0		 4l78A-1erzA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mio NITROGENASE
MOLYBDENUM IRON
PROTEIN (BETA CHAIN)

(Clostridium
pasteurianum) 		PF00148
(Oxidored_nitro) 		4 VAL B 440
THR B 438
GLU B 436
GLU B 435
 None
 1.33A 4l78A-1mioB:
0.0		 4l78A-1mioB:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8m TRIGGERING RECEPTOR
EXPRESSED ON MYELOID
CELLS 1

(Homo sapiens) 		PF07686
(V-set) 		4 VAL A 105
THR A 134
GLU A  33
GLU A 136
 None
 1.15A 4l78A-1q8mA:
0.0		 4l78A-1q8mA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3o HUNTINGTIN-ASSOCIATE
D
PROTEIN-INTERACTING
PROTEIN

(Rattus
norvegicus) 		PF00018
(SH3_1) 		4 VAL A  42
THR A  20
GLU A  43
GLU A  18
 None
 1.44A 4l78A-1u3oA:
0.0		 4l78A-1u3oA:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x4b HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEINS
A2/B1

(Homo sapiens) 		PF00076
(RRM_1) 		4 VAL A  59
THR A  40
GLU A  41
GLU A  42
 None
 1.41A 4l78A-1x4bA:
0.0		 4l78A-1x4bA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9s DNA POLYMERASE

(Escherichia
virus T7) 		PF00476
(DNA_pol_A) 		4 VAL A 470
THR A 662
GLU A 663
GLU A 664
 None
 1.30A 4l78A-1x9sA:
4.0		 4l78A-1x9sA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yb2 HYPOTHETICAL PROTEIN
TA0852

(Thermoplasma
acidophilum) 		PF08704
(GCD14) 		4 VAL A 215
THR A 214
GLU A 213
GLU A  12
 None
 1.31A 4l78A-1yb2A:
1.2		 4l78A-1yb2A:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7m N-ACYL HOMOSERINE
LACTONE HYDROLASE

(Bacillus
thuringiensis) 		PF00753
(Lactamase_B) 		4 VAL A  58
THR A  78
GLU A  79
GLU A  80
 None
GOL  A 810 (-4.6A)
None
None
 1.03A 4l78A-2a7mA:
0.0		 4l78A-2a7mA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2apo PROBABLE TRNA
PSEUDOURIDINE
SYNTHASE B

(Methanocaldococcus
jannaschii) 		PF01472
(PUA)
PF01509
(TruB_N)
PF08068
(DKCLD)
PF16198
(TruB_C_2) 		4 VAL A 252
THR A 289
GLU A 288
GLU A 242
 None
 1.18A 4l78A-2apoA:
2.5		 4l78A-2apoA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2can ORNITHINE
AMINOTRANSFERASE

(Homo sapiens) 		PF00202
(Aminotran_3) 		4 VAL A 136
THR A 128
GLU A 124
GLU A 125
 None
 1.39A 4l78A-2canA:
1.6		 4l78A-2canA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cve HYPOTHETICAL PROTEIN
TTHA1053

(Thermus
thermophilus) 		PF01205
(UPF0029)
PF09186
(DUF1949) 		4 VAL A 162
THR A 156
GLU A 155
GLU A 154
 None
 1.32A 4l78A-2cveA:
4.8		 4l78A-2cveA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cyb TYROSYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF00579
(tRNA-synt_1b) 		4 VAL A  17
THR A  19
GLU A  20
GLU A  21
 None
 1.18A 4l78A-2cybA:
undetectable		 4l78A-2cybA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3u HYPOTHETICAL PROTEIN
PH1566

(Pyrococcus
horikoshii) 		PF00013
(KH_1) 		4 VAL A  90
THR A  79
GLU A  36
GLU A  35
 None
 1.28A 4l78A-2e3uA:
undetectable		 4l78A-2e3uA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ete OXALATE OXIDASE 1

(Hordeum vulgare) 		PF00190
(Cupin_1) 		4 VAL A  56
THR A  57
GLU A  58
GLU A  63
 GLV  A 404 ( 4.7A)
None
None
None
 1.12A 4l78A-2eteA:
undetectable		 4l78A-2eteA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fc9 NCL PROTEIN

(Homo sapiens) 		PF00076
(RRM_1) 		4 VAL A  44
THR A  28
GLU A  29
GLU A  30
 None
 1.22A 4l78A-2fc9A:
2.2		 4l78A-2fc9A:
6.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fk5 FUCULOSE-1-PHOSPHATE
ALDOLASE

(Thermus
thermophilus) 		PF00596
(Aldolase_II) 		4 VAL A  72
THR A 129
GLU A 130
GLU A 131
 None
 1.28A 4l78A-2fk5A:
undetectable		 4l78A-2fk5A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 VAL A  14
THR A 250
GLU A 251
GLU A 252
 None
 0.96A 4l78A-2gp6A:
1.2		 4l78A-2gp6A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9s MESODERM DEVELOPMENT
CANDIDATE 2

(Mus musculus) 		PF10185
(Mesd) 		4 VAL A  24
THR A  33
GLU A  32
GLU A  34
 None
 0.98A 4l78A-2i9sA:
4.7		 4l78A-2i9sA:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kij COPPER-TRANSPORTING
ATPASE 1

(Homo sapiens) 		PF00122
(E1-E2_ATPase) 		4 VAL A  32
THR A  16
GLU A  30
GLU A  29
 None
 1.26A 4l78A-2kijA:
undetectable		 4l78A-2kijA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kz3 PUTATIVE
UNCHARACTERIZED
PROTEIN RAD51L3

(Homo sapiens) 		no annotation 4 VAL A   6
THR A  13
GLU A  14
GLU A  15
 None
 1.07A 4l78A-2kz3A:
undetectable		 4l78A-2kz3A:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00106
(adh_short)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 VAL A 953
THR A 950
GLU A 949
GLU A 946
 None
 1.19A 4l78A-2pffA:
undetectable		 4l78A-2pffA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pk0 SERINE/THREONINE
PROTEIN PHOSPHATASE
STP1

(Streptococcus
agalactiae) 		PF13672
(PP2C_2) 		4 VAL A 143
THR A 149
GLU A 150
GLU A 151
 None
 1.24A 4l78A-2pk0A:
undetectable		 4l78A-2pk0A:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2py2 ANTIFREEZE PROTEIN
TYPE II

(Clupea harengus) 		PF00059
(Lectin_C) 		4 VAL A  51
THR A  49
GLU A  47
GLU A  46
 None
 1.11A 4l78A-2py2A:
undetectable		 4l78A-2py2A:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q87 CMRF35-H ANTIGEN

(Homo sapiens) 		PF07686
(V-set) 		4 VAL A  11
THR A  77
GLU A  78
GLU A  79
 None
 0.86A 4l78A-2q87A:
undetectable		 4l78A-2q87A:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wge 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 1

(Mycobacterium
tuberculosis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 VAL A  15
THR A 250
GLU A 251
GLU A 252
 None
 1.06A 4l78A-2wgeA:
undetectable		 4l78A-2wgeA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfh GLUTAMATE
DEHYDROGENASE,
NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE,
GLUTAMATE
DEHYDROGENASE

(Escherichia
coli;
[Clostridium]
symbiosum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 VAL A  23
THR A  25
GLU A  27
GLU A  28
 None
 1.42A 4l78A-2yfhA:
undetectable		 4l78A-2yfhA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfk ASPARTATE/ORNITHINE
CARBAMOYLTRANSFERASE

(Enterococcus
faecalis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 VAL A 349
THR A 313
GLU A 314
GLU A 315
 None
 1.42A 4l78A-2yfkA:
undetectable		 4l78A-2yfkA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z5d UBIQUITIN-CONJUGATIN
G ENZYME E2 H

(Homo sapiens) 		PF00179
(UQ_con) 		4 VAL A  69
THR A 169
GLU A 170
GLU A 171
 None
 1.21A 4l78A-2z5dA:
undetectable		 4l78A-2z5dA:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8b FIDGETIN-LIKE
PROTEIN 1

(Homo sapiens) 		PF00004
(AAA)
PF09336
(Vps4_C) 		4 VAL A 526
THR A 522
GLU A 523
GLU A 479
 None
 1.39A 4l78A-3d8bA:
undetectable		 4l78A-3d8bA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eet PUTATIVE GNTR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
avermitilis) 		PF00392
(GntR)
PF07702
(UTRA) 		4 VAL A 190
THR A 191
GLU A 192
GLU A 193
 None
 1.22A 4l78A-3eetA:
undetectable		 4l78A-3eetA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrd NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT

(Eubacterium
barkeri) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 VAL A 274
THR A 273
GLU A 270
GLU A 269
 None
 1.11A 4l78A-3hrdA:
undetectable		 4l78A-3hrdA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jwe MGLL PROTEIN

(Homo sapiens) 		PF12146
(Hydrolase_4) 		4 VAL A 288
THR A 289
GLU A 284
GLU A 200
 None
 0.99A 4l78A-3jweA:
undetectable		 4l78A-3jweA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kg7 CURH

(Lyngbya
majuscula) 		PF14765
(PS-DH) 		4 VAL A1178
THR A1110
GLU A1180
GLU A1109
 None
 1.34A 4l78A-3kg7A:
undetectable		 4l78A-3kg7A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lzk FUMARYLACETOACETATE
HYDROLASE FAMILY
PROTEIN

(Sinorhizobium
meliloti) 		PF01557
(FAA_hydrolase) 		4 VAL A 201
THR A 202
GLU A 205
GLU A 204
 None
 1.36A 4l78A-3lzkA:
undetectable		 4l78A-3lzkA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbe MHC CLASS II H2-IAG7
BETA CHAIN

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 VAL B 140
THR B 139
GLU B 138
GLU B 137
 None
 1.32A 4l78A-3mbeB:
undetectable		 4l78A-3mbeB:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mes CHOLINE KINASE

(Cryptosporidium
parvum) 		PF01633
(Choline_kinase) 		4 VAL A 360
THR A 357
GLU A 361
GLU A 327
 None
 1.07A 4l78A-3mesA:
undetectable		 4l78A-3mesA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3noy 4-HYDROXY-3-METHYLBU
T-2-EN-1-YL
DIPHOSPHATE SYNTHASE

(Aquifex
aeolicus) 		PF04551
(GcpE) 		4 VAL A 241
THR A 245
GLU A 244
GLU A 248
 None
 1.43A 4l78A-3noyA:
undetectable		 4l78A-3noyA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o26 SALUTARIDINE
REDUCTASE

(Papaver
somniferum) 		PF00106
(adh_short)
PF13561
(adh_short_C2) 		4 VAL A 249
THR A 204
GLU A 205
GLU A 206
 None
 0.94A 4l78A-3o26A:
undetectable		 4l78A-3o26A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t12 GLIDING PROTEIN MGLA

(Thermus
thermophilus) 		PF00025
(Arf) 		4 VAL A 137
THR A 180
GLU A 183
GLU A 179
 None
 1.43A 4l78A-3t12A:
undetectable		 4l78A-3t12A:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tso RAS-RELATED PROTEIN
RAB-25

(Homo sapiens) 		PF00071
(Ras) 		4 VAL A 135
THR A 137
GLU A 139
GLU A 138
 None
 1.36A 4l78A-3tsoA:
undetectable		 4l78A-3tsoA:
8.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3umm PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE

(Salmonella
enterica) 		PF02769
(AIRS_C)
PF13507
(GATase_5) 		4 VAL A 432
THR A 581
GLU A 582
GLU A 583
 None
 0.50A 4l78A-3ummA:
63.7		 4l78A-3ummA:
99.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrd FLAVOCYTOCHROME C
FLAVIN SUBUNIT

(Thermochromatium
tepidum) 		PF07992
(Pyr_redox_2)
PF09242
(FCSD-flav_bind) 		4 VAL B 228
THR B 239
GLU B 238
GLU B 243
 None
 1.31A 4l78A-3vrdB:
undetectable		 4l78A-3vrdB:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4avy PROBABLE SHORT-CHAIN
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF13561
(adh_short_C2) 		4 VAL A 102
THR A  98
GLU A  93
GLU A  92
 None
 1.41A 4l78A-4avyA:
undetectable		 4l78A-4avyA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b8j IMPORTIN SUBUNIT
ALPHA-1A

(Oryza sativa) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		4 VAL A 300
THR A 260
GLU A 256
GLU A 257
 None
 1.29A 4l78A-4b8jA:
undetectable		 4l78A-4b8jA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bpl IMPORTIN SUBUNIT
ALPHA-1A

(Oryza sativa) 		PF00514
(Arm)
PF16186
(Arm_3) 		4 VAL A 300
THR A 260
GLU A 256
GLU A 257
 None
 1.38A 4l78A-4bplA:
undetectable		 4l78A-4bplA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccd GALACTOCEREBROSIDASE

(Mus musculus) 		PF02057
(Glyco_hydro_59)
PF17387
(Glyco_hydro_59M) 		4 VAL A 388
THR A 370
GLU A 444
GLU A 446
 None
 1.41A 4l78A-4ccdA:
undetectable		 4l78A-4ccdA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci2 PROTEIN CEREBLON

(Gallus gallus) 		PF02190
(LON_substr_bdg)
PF03226
(Yippee-Mis18) 		4 VAL B 108
THR B 155
GLU B 147
GLU B 148
 None
 1.35A 4l78A-4ci2B:
undetectable		 4l78A-4ci2B:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crm EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1

(Saccharomyces
cerevisiae) 		PF03464
(eRF1_2)
PF03465
(eRF1_3) 		4 VAL X 363
THR X 329
GLU X 366
GLU X 367
 None
 1.06A 4l78A-4crmX:
undetectable		 4l78A-4crmX:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4de9 PUTATIVE
TRANSCRIPTIONAL
REGULATOR YWTF

(Bacillus
subtilis) 		PF03816
(LytR_cpsA_psr) 		4 VAL A 145
THR A 147
GLU A 149
GLU A 150
 None
 1.36A 4l78A-4de9A:
undetectable		 4l78A-4de9A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fpw CALU16

(Micromonospora
echinospora) 		PF08327
(AHSA1) 		4 VAL A  34
THR A 108
GLU A 103
GLU A 104
 None
 1.44A 4l78A-4fpwA:
undetectable		 4l78A-4fpwA:
9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gv8 DUTPASE

(Staphylococcus
virus 11) 		PF00692
(dUTPase) 		4 VAL A  35
THR A  34
GLU A  33
GLU A 130
 None
 1.28A 4l78A-4gv8A:
undetectable		 4l78A-4gv8A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0a UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF00188
(CAP)
PF14504
(CAP_assoc_N) 		4 VAL A 113
THR A 107
GLU A 111
GLU A 110
 None
 1.40A 4l78A-4h0aA:
undetectable		 4l78A-4h0aA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hlu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA

(Thermotoga
maritima) 		no annotation 4 VAL D1187
THR D1188
GLU D1157
GLU D1190
 None
ACT  D1302 (-3.3A)
ACT  D1302 (-4.6A)
ACT  D1302 (-4.9A)
 1.42A 4l78A-4hluD:
undetectable		 4l78A-4hluD:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i4j ACP-POLYENE
THIOESTERASE

(Streptomyces
globisporus) 		PF13279
(4HBT_2) 		4 VAL A  26
THR A  20
GLU A  19
GLU A  18
 None
 1.26A 4l78A-4i4jA:
undetectable		 4l78A-4i4jA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i8v CYTOCHROME P450 1A1

(Homo sapiens) 		PF00067
(p450) 		4 VAL A 350
THR A 349
GLU A 346
GLU A 345
 None
 1.38A 4l78A-4i8vA:
undetectable		 4l78A-4i8vA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jeu SYNTAXIN-BINDING
PROTEIN 1

(Rattus
norvegicus) 		PF00995
(Sec1) 		4 VAL A 451
THR A 419
GLU A 420
GLU A 421
 None
 1.08A 4l78A-4jeuA:
undetectable		 4l78A-4jeuA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jo8 M157

(Murid
betaherpesvirus
1) 		PF11624
(M157) 		4 VAL A 241
THR A 242
GLU A 243
GLU A 244
 None
 1.17A 4l78A-4jo8A:
undetectable		 4l78A-4jo8A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpr THIOREDOXIN
REDUCTASE 1,
CYTOPLASMIC

(Rattus
norvegicus) 		no annotation 4 VAL E 318
THR E 319
GLU E 322
GLU E 321
 MPD  E 504 (-4.7A)
MPD  E 504 (-4.8A)
None
None
 1.27A 4l78A-4kprE:
undetectable		 4l78A-4kprE:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ktp GLYCOSIDE HYDROLASE
FAMILY 65 CENTRAL
CATALYTIC

([Bacillus]
selenitireducens) 		PF03632
(Glyco_hydro_65m)
PF03633
(Glyco_hydro_65C)
PF03636
(Glyco_hydro_65N) 		4 VAL A 110
THR A 111
GLU A 130
GLU A 129
 None
 1.10A 4l78A-4ktpA:
undetectable		 4l78A-4ktpA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kxb GLUTAMYL
AMINOPEPTIDASE

(Homo sapiens) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 VAL A 261
THR A 275
GLU A 264
GLU A 265
 None
 1.02A 4l78A-4kxbA:
undetectable		 4l78A-4kxbA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lq8 SCA-FAMILY PROTEIN

(Rickettsia
rickettsii) 		PF12574
(120_Rick_ant) 		4 VAL A 221
THR A 220
GLU A 243
GLU A 218
 None
 1.42A 4l78A-4lq8A:
undetectable		 4l78A-4lq8A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n13 PHOSPHATE ABC
TRANSPORTER,
PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN

(Borreliella
burgdorferi) 		PF12849
(PBP_like_2) 		4 VAL A 201
THR A  99
GLU A 100
GLU A 101
 None
 1.32A 4l78A-4n13A:
undetectable		 4l78A-4n13A:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9b STROMAL INTERACTION
MOLECULE 1

(Homo sapiens) 		no annotation 4 VAL A 275
THR A 274
GLU A 271
GLU A 270
 None
 1.10A 4l78A-4o9bA:
undetectable		 4l78A-4o9bA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ozt RETINOID X RECEPTOR

(Pediculus
humanus) 		PF00104
(Hormone_recep) 		4 VAL U 339
THR U 337
GLU U 335
GLU U 334
 None
 1.34A 4l78A-4oztU:
undetectable		 4l78A-4oztU:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p5t PROTEIN OF 3K
PEPTIDE
(FEAQKAKANKAVD),LINK
ER REGION -
GGGGSLVPRGSGGGG,H-2
CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A BETA
CHAIN,H-2 CLASS II
HISTOCOMPATIBILITY
ANTIGEN, A BETA
CHAIN

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 VAL D 141
THR D 140
GLU D 139
GLU D 138
 None
 1.35A 4l78A-4p5tD:
undetectable		 4l78A-4p5tD:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qbu ZMAA

(Bacillus cereus) 		PF00698
(Acyl_transf_1) 		4 VAL A 228
THR A 269
GLU A 270
GLU A 271
 None
 1.20A 4l78A-4qbuA:
undetectable		 4l78A-4qbuA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rx4 HIV-1 CLADE A
Q842.D12 GP120

(Human
immunodeficiency
virus 1) 		no annotation 4 VAL G  89
THR G  90
GLU G  91
GLU G  92
 None
 1.38A 4l78A-4rx4G:
undetectable		 4l78A-4rx4G:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tnm IMPORTIN SUBUNIT
ALPHA

(Arabidopsis
thaliana) 		PF00514
(Arm)
PF01749
(IBB)
PF16186
(Arm_3) 		4 VAL A 303
THR A 263
GLU A 259
GLU A 260
 None
 1.33A 4l78A-4tnmA:
undetectable		 4l78A-4tnmA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tx2 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Actinoplanes
teichomyceticus) 		PF00668
(Condensation) 		4 VAL B 365
THR B 402
GLU B 403
GLU B 368
 None
 1.18A 4l78A-4tx2B:
undetectable		 4l78A-4tx2B:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zr5 NEPRILYSIN

(Oryctolagus
cuniculus) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		4 VAL A 344
THR A 304
GLU A 342
GLU A 341
 None
 1.35A 4l78A-4zr5A:
undetectable		 4l78A-4zr5A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwa ORNITHINE
DECARBOXYLASE

(Homo sapiens) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 VAL A 254
THR A 252
GLU A 250
GLU A 249
 None
 1.21A 4l78A-5bwaA:
undetectable		 4l78A-5bwaA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dle PTS SYSTEM,
FRUCTOSE-SPECIFIC
IIABC COMPONENT

(Borreliella
burgdorferi) 		PF02302
(PTS_IIB) 		4 VAL A 169
THR A 201
GLU A 200
GLU A 208
 None
 1.42A 4l78A-5dleA:
undetectable		 4l78A-5dleA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5evm FUSION GLYCOPROTEIN
F0

(Nipah
henipavirus) 		PF00523
(Fusion_gly) 		4 VAL A 169
THR A 168
GLU A 163
GLU A 166
 None
 1.43A 4l78A-5evmA:
undetectable		 4l78A-5evmA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f07 PUTATIVE GLUTATHIONE
S-TRANSFERASE FAMILY
PROTEIN

(Populus
trichocarpa) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 VAL A 133
THR A 135
GLU A 137
GLU A 138
 None
 1.39A 4l78A-5f07A:
undetectable		 4l78A-5f07A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5id6 CPF1

(Lachnospiraceae
bacterium
ND2006) 		no annotation 4 VAL A 377
THR A 378
GLU A 382
GLU A 379
 None
 1.19A 4l78A-5id6A:
undetectable		 4l78A-5id6A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis) 		PF05853
(BKACE) 		4 VAL A 501
THR A 497
GLU A 219
GLU A 215
 None
 1.36A 4l78A-5ikzA:
undetectable		 4l78A-5ikzA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7u MAJOR CAPSID PROTEIN

(Faustovirus) 		PF04451
(Capsid_NCLDV) 		4 VAL A 473
THR A 520
GLU A 519
GLU A 521
 None
 1.43A 4l78A-5j7uA:
undetectable		 4l78A-5j7uA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j98 VP2

(Slow bee
paralysis virus) 		PF00073
(Rhv) 		4 VAL B  12
THR B  11
GLU B  21
GLU B   9
 None
 1.38A 4l78A-5j98B:
undetectable		 4l78A-5j98B:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 VAL A 605
THR A 589
GLU A 607
GLU A 588
 None
 1.00A 4l78A-5kf7A:
undetectable		 4l78A-5kf7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 VAL A 605
THR A 606
GLU A 607
GLU A 588
 None
 1.21A 4l78A-5kf7A:
undetectable		 4l78A-5kf7A:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mmx CSPYL1_ABA

(Citrus sinensis) 		no annotation 4 VAL B 176
THR B 181
GLU B 182
GLU B 183
 None
 1.21A 4l78A-5mmxB:
undetectable		 4l78A-5mmxB:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mob SLPYL1_ABA

(Solanum
lycopersicum) 		PF10604
(Polyketide_cyc2) 		4 VAL A 184
THR A 189
GLU A 190
GLU A 191
 None
SO4  A 302 (-4.1A)
None
None
 1.36A 4l78A-5mobA:
undetectable		 4l78A-5mobA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5np4 TRANSCOBALAMIN-2

(Homo sapiens) 		PF14478
(DUF4430) 		4 VAL A 314
THR A 315
GLU A 400
GLU A 403
 None
 1.30A 4l78A-5np4A:
undetectable		 4l78A-5np4A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2d POLY [ADP-RIBOSE]
POLYMERASE 14

(Homo sapiens) 		no annotation 4 VAL A1065
THR A1064
GLU A1061
GLU A1060
 None
 1.23A 4l78A-5o2dA:
undetectable		 4l78A-5o2dA:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5twb FERREDOXIN--NADP
REDUCTASE

(Staphylococcus
aureus) 		PF07992
(Pyr_redox_2) 		4 VAL A  84
THR A  98
GLU A  97
GLU A 102
 None
 1.17A 4l78A-5twbA:
undetectable		 4l78A-5twbA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2

(Arabidopsis
thaliana) 		PF00201
(UDPGT) 		4 VAL A 384
THR A 386
GLU A 397
GLU A 387
 None
 1.32A 4l78A-5u6sA:
undetectable		 4l78A-5u6sA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uth THIOREDOXIN
REDUCTASE

(Mycolicibacterium
smegmatis) 		PF07992
(Pyr_redox_2) 		4 VAL A 134
THR A 130
GLU A 126
GLU A 127
 None
 1.24A 4l78A-5uthA:
undetectable		 4l78A-5uthA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uwy THIOREDOXIN
REDUCTASE

(Streptococcus
pyogenes) 		PF07992
(Pyr_redox_2) 		4 VAL A 127
THR A 123
GLU A 119
GLU A 120
 None
 1.45A 4l78A-5uwyA:
undetectable		 4l78A-5uwyA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v4b F-BOX/WD
REPEAT-CONTAINING
PROTEIN 7

(Homo sapiens) 		PF00400
(WD40)
PF12937
(F-box-like) 		4 VAL B2686
THR B2695
GLU B2693
GLU B2694
 None
 0.98A 4l78A-5v4bB:
undetectable		 4l78A-5v4bB:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdu ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 4 VAL G  89
THR G  90
GLU G  91
GLU G  92
 None
 1.36A 4l78A-5wduG:
undetectable		 4l78A-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wdu ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 4 VAL G 242
THR G  90
GLU G  91
GLU G  92
 None
 1.37A 4l78A-5wduG:
undetectable		 4l78A-5wduG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xap PROTEIN TRANSLOCASE
SUBUNIT SECD

(Deinococcus
radiodurans) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG) 		4 VAL A 501
THR A 586
GLU A 585
GLU A 284
 None
 1.17A 4l78A-5xapA:
undetectable		 4l78A-5xapA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6q ALDEHYDE OXIDASE
MEDIUM SUBUNIT

(Methylobacillus
sp. KY4400) 		no annotation 4 VAL B 179
THR B 186
GLU B 212
GLU B 185
 None
 1.38A 4l78A-5y6qB:
undetectable		 4l78A-5y6qB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bz0 DIHYDROLIPOYL
DEHYDROGENASE

(Acinetobacter
baumannii) 		no annotation 4 VAL A 405
THR A 368
GLU A 369
GLU A 370
 None
CL  A 504 ( 4.1A)
None
CL  A 504 (-4.1A)
 0.92A 4l78A-6bz0A:
undetectable		 4l78A-6bz0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co9 PROBABLE
COA-TRANSFERASE
ALPHA SUBUNIT

(Rhodococcus
jostii) 		no annotation 4 VAL A 209
THR A 211
GLU A 213
GLU A 212
 None
 1.39A 4l78A-6co9A:
undetectable		 4l78A-6co9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6con COA-TRANSFERASE
SUBUNIT ALPHA

(Mycobacterium
tuberculosis) 		no annotation 4 VAL A 206
THR A 208
GLU A 210
GLU A 209
 None
 1.43A 4l78A-6conA:
undetectable		 4l78A-6conA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d0p PIRIN FAMILY PROTEIN

(Acinetobacter
baumannii) 		no annotation 4 VAL A  77
THR A  78
GLU A 107
GLU A 106
 None
None
MN  A 303 ( 2.9A)
MG  A 301 ( 4.0A)
 1.40A 4l78A-6d0pA:
undetectable		 4l78A-6d0pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6esq HYDROXYMETHYLGLUTARY
L-COA SYNTHASE

(Methanothermococcus
thermolithotrophicus) 		no annotation 4 VAL I  57
THR I  54
GLU I  58
GLU I  50
 None
 1.33A 4l78A-6esqI:
undetectable		 4l78A-6esqI:
undetectable