SIMILAR PATTERNS OF AMINO ACIDS FOR 4L39_B_SALB601
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d2e | ELONGATION FACTOR TU(EF-TU) (Bos taurus) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | THR A 139ILE A 106THR A 430GLY A 432 | None | 0.89A | 4l39B-1d2eA:undetectable | 4l39B-1d2eA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnn | CELL DIVISIONCONTROL PROTEIN 6 (Pyrobaculumaerophilum) |
PF09079(Cdc6_C)PF13401(AAA_22) | 4 | LEU A 274THR A 226ILE A 222GLY A 368 | None | 0.89A | 4l39B-1fnnA:0.4 | 4l39B-1fnnA:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jsd | HAEMAGGLUTININ (HA1CHAIN) (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 184TYR A 185ILE A 242GLY A 128 | None | 0.90A | 4l39B-1jsdA:undetectable | 4l39B-1jsdA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lxy | ARGININE DEIMINASE (Mycoplasmaarginini) |
PF02274(Amidinotransf) | 5 | LEU A 374TYR A 353THR A 370ILE A 332THR A 275 | None | 1.48A | 4l39B-1lxyA:undetectable | 4l39B-1lxyA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oi1 | SCML2 PROTEIN (Homo sapiens) |
PF02820(MBT) | 4 | LEU A 109ILE A 189THR A 233GLY A 90 | None | 0.89A | 4l39B-1oi1A:undetectable | 4l39B-1oi1A:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1osg | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B (Homo sapiens) |
PF00229(TNF) | 4 | LEU A 261THR A 277ILE A 270GLY A 209 | None | 0.86A | 4l39B-1osgA:undetectable | 4l39B-1osgA:16.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pw5 | NAGD PROTEIN,PUTATIVE (Thermotogamaritima) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | LEU A 92THR A 95THR A 146GLY A 74 | None | 0.88A | 4l39B-1pw5A:1.5 | 4l39B-1pw5A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q90 | APOCYTOCHROME F (Chlamydomonasreinhardtii) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 4 | LEU A 100TYR A 102ILE A 49GLY A 72 | NoneNoneNoneHEM A 900 (-3.9A) | 0.89A | 4l39B-1q90A:undetectable | 4l39B-1q90A:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rty | YVQK PROTEIN (Bacillussubtilis) |
PF01923(Cob_adeno_trans) | 4 | LEU A 93TYR A 152ILE A 40THR A 129 | None | 0.93A | 4l39B-1rtyA:undetectable | 4l39B-1rtyA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ti8 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.95A | 4l39B-1ti8A:undetectable | 4l39B-1ti8A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v29 | NITRILE HYDRATASE BCHAIN (Bacillussmithii) |
PF02211(NHase_beta) | 4 | LEU B 206ILE B 217THR B 150GLY B 170 | None | 0.96A | 4l39B-1v29B:undetectable | 4l39B-1v29B:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xaj | 3-DEHYDROQUINATESYNTHASE (Staphylococcusaureus) |
PF01761(DHQ_synthase) | 4 | LEU A 184TYR A 180ILE A 265GLY A 241 | None | 0.88A | 4l39B-1xajA:undetectable | 4l39B-1xajA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xsa | BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (Homo sapiens) |
PF00293(NUDIX) | 4 | THR A 95ILE A 97THR A 59GLY A 48 | None | 0.96A | 4l39B-1xsaA:undetectable | 4l39B-1xsaA:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b3d | MODULATOR OF DRUGACTIVITY B (Escherichiacoli) |
PF02525(Flavodoxin_2) | 4 | LEU A 199TYR A 195ILE A 17GLY A 41 | None | 0.82A | 4l39B-2b3dA:1.8 | 4l39B-2b3dA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g02 | NISIN BIOSYNTHESISPROTEIN NISC (Lactococcuslactis) |
PF05147(LANC_like) | 4 | LEU A 39TYR A 88ILE A 329GLY A 377 | None | 0.73A | 4l39B-2g02A:undetectable | 4l39B-2g02A:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hdn | ELONGATION FACTOREF-TU (Escherichiacoli) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | LEU B 311THR B 382THR B 93GLY B 386 | None | 0.96A | 4l39B-2hdnB:1.4 | 4l39B-2hdnB:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hf8 | PROBABLE HYDROGENASENICKEL INCORPORATIONPROTEIN HYPB (Methanocaldococcusjannaschii) |
PF02492(cobW) | 4 | LEU A 28THR A 135ILE A 119GLY A 103 | None | 0.72A | 4l39B-2hf8A:1.9 | 4l39B-2hf8A:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iun | AVIAN ADENOVIRUSCELO LONG FIBRE (Fowlaviadenovirus A) |
PF16812(AdHead_fibreRBD) | 4 | LEU A 759THR A 781ILE A 784GLY A 756 | None | 0.92A | 4l39B-2iunA:undetectable | 4l39B-2iunA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nmp | CYSTATHIONINEGAMMA-LYASE (Homo sapiens) |
PF01053(Cys_Met_Meta_PP) | 4 | THR A 163ILE A 369THR A 355GLY A 115 | None | 0.96A | 4l39B-2nmpA:undetectable | 4l39B-2nmpA:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p0k | POLYCOMB PROTEINSCMH1 (Homo sapiens) |
PF02820(MBT) | 4 | LEU A 104ILE A 184THR A 228GLY A 85 | None | 0.80A | 4l39B-2p0kA:undetectable | 4l39B-2p0kA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v4y | URIDYLATE KINASE (Escherichiacoli) |
PF00696(AA_kinase) | 4 | LEU A 197THR A 172THR A 237GLY A 169 | None | 0.84A | 4l39B-2v4yA:undetectable | 4l39B-2v4yA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wrd | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 193TYR A 194ILE A 251GLY A 133 | None | 0.87A | 4l39B-2wrdA:undetectable | 4l39B-2wrdA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y89 | PHOSPHORIBOSYLISOMERASE A (Mycobacteriumtuberculosis) |
PF00977(His_biosynth) | 4 | LEU A 185THR A 170ILE A 172GLY A 176 | None | 0.91A | 4l39B-2y89A:undetectable | 4l39B-2y89A:17.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yp2 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.82A | 4l39B-2yp2A:undetectable | 4l39B-2yp2A:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ai7 | XYLULOSE-5-PHOSPHATE/FRUCTOSE-6-PHOSPHATE PHOSPHOKETOLASE (Bifidobacteriumlongum) |
PF03894(XFP)PF09363(XFP_C)PF09364(XFP_N) | 4 | TYR A 447THR A 438ILE A 432GLY A 416 | None | 0.93A | 4l39B-3ai7A:undetectable | 4l39B-3ai7A:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bga | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | TYR A 898ARG A 901THR A 927GLY A 554 | None | 0.86A | 4l39B-3bgaA:undetectable | 4l39B-3bgaA:20.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cr3 | PTS-DEPENDENTDIHYDROXYACETONEKINASE, ADP-BINDINGSUBUNIT DHALPTS-DEPENDENTDIHYDROXYACETONEKINASE,PHOSPHOTRANSFERASESUBUNIT DHAM (Lactococcuslactis) |
PF02734(Dak2)PF03610(EIIA-man) | 4 | LEU C 67ILE C 42THR C 44GLY A 77 | NoneNoneNoneADP A1211 (-3.3A) | 0.88A | 4l39B-3cr3C:undetectable | 4l39B-3cr3C:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d46 | PUTATIVE GALACTONATEDEHYDRATASE (Salmonellaenterica) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | THR A 123ILE A 137THR A 284GLY A 130 | None | 0.91A | 4l39B-3d46A:undetectable | 4l39B-3d46A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d6k | PUTATIVEAMINOTRANSFERASE (Corynebacteriumdiphtheriae) |
PF12897(Aminotran_MocR) | 4 | LEU A 50ILE A 78THR A 253GLY A 262 | None | 0.91A | 4l39B-3d6kA:undetectable | 4l39B-3d6kA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dec | BETA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | TYR A 874ARG A 877THR A 903GLY A 530 | None | 0.89A | 4l39B-3decA:3.0 | 4l39B-3decA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eof | PUTATIVEOXIDOREDUCTASE (Bacteroidesfragilis) |
PF00881(Nitroreductase) | 4 | THR A 75ILE A 140THR A 134GLY A 131 | NoneNoneNoneFMN A 300 (-3.5A) | 0.74A | 4l39B-3eofA:undetectable | 4l39B-3eofA:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eyk | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 196TYR A 197ILE A 254GLY A 134 | None | 0.95A | 4l39B-3eykA:undetectable | 4l39B-3eykA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f72 | CADMIUM EFFLUXSYSTEM ACCESSORYPROTEIN (Staphylococcusaureus) |
PF01022(HTH_5) | 4 | LEU A 99THR A 48ILE A 39GLY A 84 | None | 0.83A | 4l39B-3f72A:undetectable | 4l39B-3f72A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gde | DNA LIGASE (Archaeoglobusfulgidus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | LEU A 70TYR A 144ILE A 159GLY A 64 | None | 0.81A | 4l39B-3gdeA:undetectable | 4l39B-3gdeA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9d | OUTER CAPSID PROTEINVP2 (Bluetonguevirus) |
PF00898(Orbi_VP2) | 4 | LEU A 604TYR A 600THR A 621GLY A 161 | None | 0.92A | 4l39B-3j9dA:3.1 | 4l39B-3j9dA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpd | ACIDIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE APRV2 (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | LEU A 321THR A 229ILE A 329GLY A 326 | None | 0.89A | 4l39B-3lpdA:undetectable | 4l39B-3lpdA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwf | PUTATIVETRANSCRIPTIONALREGULATOR (Listeriainnocua) |
PF02082(Rrf2) | 4 | LEU A 67THR A 14ILE A 79GLY A 53 | None | 0.93A | 4l39B-3lwfA:undetectable | 4l39B-3lwfA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n79 | PDUT (Salmonellaenterica) |
PF00936(BMC) | 4 | LEU A 10THR A 61ILE A 57GLY A 20 | None | 0.95A | 4l39B-3n79A:undetectable | 4l39B-3n79A:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o59 | DNA POLYMERASE IILARGE SUBUNIT (Pyrococcushorikoshii) |
PF03833(PolC_DP2) | 4 | LEU X 250TYR X 194THR X 226GLY X 148 | None | 0.90A | 4l39B-3o59X:2.2 | 4l39B-3o59X:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqi | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | NoneNoneNoneEPE A3380 (-3.4A) | 0.81A | 4l39B-3qqiA:undetectable | 4l39B-3qqiA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r5t | FERRIC VIBRIOBACTINABC TRANSPORTER,PERIPLASMIC FERRICVIBRIOBACTIN-BINDINGPROTEIN (Vibrio cholerae) |
PF01497(Peripla_BP_2) | 4 | LEU A 65ILE A 142THR A 162GLY A 159 | None | 0.91A | 4l39B-3r5tA:undetectable | 4l39B-3r5tA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 4 | LEU M 211TYR M 207ILE M 496GLY M 59 | None | 0.85A | 4l39B-3rkoM:undetectable | 4l39B-3rkoM:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ti7 | BASIC EXTRACELLULARSUBTILISIN-LIKEPROTEASE BPRV (Dichelobacternodosus) |
PF00082(Peptidase_S8) | 4 | LEU A 321THR A 229ILE A 329GLY A 326 | None | 0.89A | 4l39B-3ti7A:undetectable | 4l39B-3ti7A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u04 | PEPTIDE DEFORMYLASE1 (Ehrlichiachaffeensis) |
PF01327(Pep_deformylase) | 4 | LEU A 14THR A 8ILE A 6GLY A 53 | None | 0.87A | 4l39B-3u04A:undetectable | 4l39B-3u04A:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyy | IRON-SULFUR CLUSTERBINDING PROTEIN (Carboxydothermushydrogenoformans) |
PF00111(Fer2)PF14574(DUF4445) | 4 | LEU X 116THR X 364ILE X 539GLY X 571 | None | 0.90A | 4l39B-3zyyX:undetectable | 4l39B-3zyyX:23.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2b | CELL DIVISIONPROTEIN FTSA,PUTATIVE (Thermotogamaritima) |
PF02491(SHS2_FTSA)PF14450(FtsA) | 4 | LEU A 64ILE A 81THR A 11GLY A 22 | None | 0.79A | 4l39B-4a2bA:undetectable | 4l39B-4a2bA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cs6 | AMINOGLYCOSIDEADENYLTRANSFERASE (Salmonellaenterica) |
PF01909(NTP_transf_2)PF13427(DUF4111) | 4 | LEU A 50THR A 13ILE A 5GLY A 35 | None | 0.93A | 4l39B-4cs6A:undetectable | 4l39B-4cs6A:18.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4j | ARGININE DEIMINASE (Mycoplasmapenetrans) |
PF02274(Amidinotransf) | 5 | LEU A 416TYR A 395THR A 412ILE A 374THR A 319 | None | 1.42A | 4l39B-4e4jA:undetectable | 4l39B-4e4jA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g5e | 2,4,6-TRICHLOROPHENOL 4-MONOOXYGENASE (Cupriaviduspinatubonensis) |
PF03241(HpaB)PF11794(HpaB_N) | 4 | LEU A 253THR A 34ILE A 25GLY A 21 | None | 0.93A | 4l39B-4g5eA:undetectable | 4l39B-4g5eA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hfu | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.94A | 4l39B-4hfuA:undetectable | 4l39B-4hfuA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkx | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU E 194TYR E 195ILE E 252GLY E 134 | None | 0.84A | 4l39B-4hkxE:undetectable | 4l39B-4hkxE:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0q | ELONGATION FACTORTU-A (Pseudomonasputida) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | LEU A 315THR A 386THR A 94GLY A 390 | None | 0.96A | 4l39B-4j0qA:1.5 | 4l39B-4j0qA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhi | MTN13 PROTEIN (Medicagotruncatula) |
PF00407(Bet_v_1) | 4 | LEU A 90TYR A 133ILE A 98GLY A 87 | NoneEMU A 202 ( 4.3A)EMU A 202 ( 4.9A)None | 0.82A | 4l39B-4jhiA:undetectable | 4l39B-4jhiA:14.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l27 | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
no annotation | 4 | THR B 150ILE B 122THR B 260GLY B 258 | NoneNonePLP B 601 (-3.3A)PLP B 601 (-3.5A) | 0.95A | 4l39B-4l27B:undetectable | 4l39B-4l27B:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmb | CYSTEINE SYNTHASE (Microcystisaeruginosa) |
PF00291(PALP) | 4 | THR A 78ILE A 49THR A 185GLY A 183 | CYS A 401 (-3.9A)NonePLP A 403 (-3.5A)PLP A 403 (-3.4A) | 0.88A | 4l39B-4lmbA:2.2 | 4l39B-4lmbA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mae | METHANOLDEHYDROGENASE (Methylacidiphilumfumariolicum) |
PF13360(PQQ_2) | 4 | ARG A 265THR A 370THR A 259GLY A 427 | None | 0.65A | 4l39B-4maeA:undetectable | 4l39B-4maeA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mb7 | ENDONUCLEASE 8-LIKEL720 (Acanthamoebapolyphagamimivirus) |
PF06831(H2TH) | 4 | TYR A 103THR A 85ILE A 91GLY A 79 | None | 0.71A | 4l39B-4mb7A:undetectable | 4l39B-4mb7A:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mca | GLYCEROLDEHYDROGENASE (Serratiaplymuthica) |
PF00465(Fe-ADH) | 4 | LEU A 211TYR A 207ARG A 204THR A 295 | None | 0.93A | 4l39B-4mcaA:undetectable | 4l39B-4mcaA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mea | PREDICTED PROTEIN (Acinetobacternosocomialis) |
PF00561(Abhydrolase_1) | 4 | LEU A 167TYR A 154ILE A 114GLY A 141 | None | 0.88A | 4l39B-4meaA:undetectable | 4l39B-4meaA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o87 | N-TAGGED NUCLEASE (Millerozymaacaciae) |
no annotation | 4 | LEU A 200ILE A 268THR A 183GLY A 180 | None | 0.80A | 4l39B-4o87A:undetectable | 4l39B-4o87A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oul | CAPRIN-2 (Homo sapiens) |
PF00386(C1q) | 4 | LEU A1123TYR A1045THR A1029GLY A1027 | None | 0.90A | 4l39B-4oulA:undetectable | 4l39B-4oulA:12.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ovm | UNCHARACTERIZEDPROTEIN SGCJ (Streptomycescarzinostaticus) |
PF14534(DUF4440) | 4 | TYR A 136ILE A 118THR A 100GLY A 83 | None | 0.76A | 4l39B-4ovmA:undetectable | 4l39B-4ovmA:13.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0d | TRYPSIN-RESISTANTSURFACE T6 PROTEIN (Streptococcuspyogenes) |
PF16569(GramPos_pilinBB) | 4 | LEU A 199THR A 439ILE A 480GLY A 456 | None | 0.96A | 4l39B-4p0dA:undetectable | 4l39B-4p0dA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4we6 | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 154TYR A 155ILE A 212GLY A 94 | NoneNoneNoneGOL A 303 (-3.4A) | 0.86A | 4l39B-4we6A:undetectable | 4l39B-4we6A:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y23 | GAMMA GLUTAMYLTRANSPEPTIDASE,GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 4 | LEU A 60THR A 405ILE A 554GLY A 40 | None | 0.90A | 4l39B-4y23A:undetectable | 4l39B-4y23A:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zcf | RESTRICTIONENDONUCLEASEECOP15I, RESTRICTIONSUBUNIT (Escherichiacoli) |
PF04851(ResIII) | 4 | LEU C 267TYR C 265THR C 93GLY C 89 | NoneNoneNoneAMP C1001 (-3.4A) | 0.95A | 4l39B-4zcfC:1.6 | 4l39B-4zcfC:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zch | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B (Homo sapiens) |
PF00229(TNF) | 4 | LEU A 269THR A 285ILE A 278GLY A 217 | None | 0.87A | 4l39B-4zchA:undetectable | 4l39B-4zchA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zch | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B,TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER13B (Homo sapiens) |
PF00229(TNF) | 4 | LEU A 420THR A 436ILE A 429GLY A 368 | None | 0.88A | 4l39B-4zchA:undetectable | 4l39B-4zchA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zv4 | ELONGATION FACTOR TU (Pseudomonasaeruginosa) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3)PF03144(GTP_EFTU_D2) | 4 | LEU A 315THR A 386THR A 94GLY A 390 | None | 0.92A | 4l39B-4zv4A:1.1 | 4l39B-4zv4A:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | REELIN (Mus musculus) |
PF07974(EGF_2) | 4 | LEU A2014ILE A2022THR A2020GLY A2130 | None | 0.82A | 4l39B-5b4xA:undetectable | 4l39B-5b4xA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c9e | SEPL (Escherichiacoli) |
PF07201(HrpJ) | 4 | LEU A 167ILE A 100THR A 95GLY A 172 | None | 0.72A | 4l39B-5c9eA:undetectable | 4l39B-5c9eA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dm3 | L-GLUTAMINESYNTHETASE (Chromohalobactersalexigens) |
PF00120(Gln-synt_C) | 4 | ARG A 190THR A 179THR A 203GLY A 205 | None | 0.87A | 4l39B-5dm3A:undetectable | 4l39B-5dm3A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gne | LEUCINEAMINOPEPTIDASE (Legionellapneumophila) |
PF04389(Peptidase_M28) | 4 | LEU A 287THR A 384ILE A 136GLY A 291 | None | 0.91A | 4l39B-5gneA:undetectable | 4l39B-5gneA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 4 | LEU A 391TYR A 382ARG A 389GLY A 248 | None | 0.78A | 4l39B-5gnmA:undetectable | 4l39B-5gnmA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hc8 | PRENYLTRANSFERENCEFOR PROTEIN (Lavandulalanata) |
PF01255(Prenyltransf) | 4 | LEU A 135TYR A 139ILE A 75GLY A 92 | 61G A 403 ( 4.5A)NoneNoneNone | 0.92A | 4l39B-5hc8A:undetectable | 4l39B-5hc8A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huq | LACTATE RACEMIZATIONOPERON PROTEIN LARA (Lactobacillusplantarum) |
PF09861(DUF2088) | 4 | LEU A 147ILE A 155THR A 230GLY A 145 | None | 0.96A | 4l39B-5huqA:undetectable | 4l39B-5huqA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | TYR A 23ILE A 812THR A 824GLY A 340 | None | 0.92A | 4l39B-5i2gA:undetectable | 4l39B-5i2gA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kan | HEMAGGLUTININ HA1 (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.92A | 4l39B-5kanA:undetectable | 4l39B-5kanA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kia | L-THREONINE3-DEHYDROGENASE (Burkholderiathailandensis) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | LEU A 4ILE A 37THR A 35GLY A 62 | None | 0.96A | 4l39B-5kiaA:undetectable | 4l39B-5kiaA:21.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l46 | DIMETHYLGLYCINEDEHYDROGENASE,MITOCHONDRIAL (Homo sapiens) |
PF01266(DAO)PF01571(GCV_T)PF08669(GCV_T_C)PF16350(FAO_M) | 4 | LEU A 198TYR A 116THR A 96GLY A 94 | NoneNoneNoneFAD A 901 ( 4.4A) | 0.88A | 4l39B-5l46A:undetectable | 4l39B-5l46A:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc5 | NADH DEHYDROGENASE[UBIQUINONE]IRON-SULFUR PROTEIN3, MITOCHONDRIAL (Bos taurus) |
PF00329(Complex1_30kDa) | 4 | LEU C 61TYR C 94ILE C 117GLY C 56 | None | 0.71A | 4l39B-5lc5C:undetectable | 4l39B-5lc5C:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m3q | EUKARYOTICTRANSLATIONINITIATION FACTOR 6 (Chaetomiumthermophilum) |
PF01912(eIF-6) | 4 | LEU A 25ILE A 92THR A 20GLY A 65 | None | 0.96A | 4l39B-5m3qA:undetectable | 4l39B-5m3qA:17.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8j | DIVALENT METALCATION TRANSPORTERMNTH (Eremococcuscoleocola) |
PF01566(Nramp) | 4 | ARG A 369THR A 350ILE A 122THR A 372 | None | 0.75A | 4l39B-5m8jA:undetectable | 4l39B-5m8jA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n1q | METHYL-COENZYME MREDUCTASE III FROMMETHANOTHERMOCOCCUSTHERMOLITHOTROPHICUSSUBUNIT BETA (Methanothermococcusthermolithotrophicus) |
PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | THR B 45ILE B 422THR B 203GLY B 416 | None | 0.95A | 4l39B-5n1qB:undetectable | 4l39B-5n1qB:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n28 | METHYL-COENZYME MREDUCTASE, BETASUBUNIT (Methanotorrisformicicus) |
PF02241(MCR_beta)PF02783(MCR_beta_N) | 4 | THR B 45ILE B 423THR B 203GLY B 417 | None | 0.96A | 4l39B-5n28B:undetectable | 4l39B-5n28B:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfh | METHIONYL-TRNASYNTHETASE, PUTATIVE (Trypanosomabrucei) |
no annotation | 4 | ARG A 451THR A 398ILE A 365THR A 455 | None | 0.94A | 4l39B-5nfhA:undetectable | 4l39B-5nfhA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tg8 | HEMAGGLUTININ HA1CHAIN (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.93A | 4l39B-5tg8A:undetectable | 4l39B-5tg8A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tr7 | D-ALANYL-D-ALANINECARBOXYPEPTIDASE (Vibrio cholerae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 4 | LEU A 191TYR A 202ILE A 125GLY A 77 | None | 0.96A | 4l39B-5tr7A:undetectable | 4l39B-5tr7A:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w6t | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.91A | 4l39B-5w6tA:undetectable | 4l39B-5w6tA:18.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w75 | ELONGATION FACTOR TU (Thermotoganeapolitana) |
no annotation | 4 | THR A 94ILE A 61THR A 383GLY A 385 | None | 0.94A | 4l39B-5w75A:0.7 | 4l39B-5w75A:9.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xl6 | HEMAGGLUTININ (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | LEU A 191TYR A 192ILE A 249GLY A 130 | SIA A 603 (-4.7A)NoneNoneSIA A 603 ( 4.4A) | 0.90A | 4l39B-5xl6A:undetectable | 4l39B-5xl6A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xra | CANNABINOID RECEPTOR1,FLAVODOXIN,CANNABINOID RECEPTOR 1 (Desulfovibriovulgaris;Homo sapiens) |
PF00001(7tm_1)PF00258(Flavodoxin_1) | 4 | LEU A 286THR A 201ILE A 247GLY A 281 | None | 0.74A | 4l39B-5xraA:undetectable | 4l39B-5xraA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xrt | - (-) |
no annotation | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.92A | 4l39B-5xrtA:undetectable | 4l39B-5xrtA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xs9 | TETR FAMILYTRANSCRIPTIONALREGULATOR (Mycolicibacteriumsmegmatis) |
no annotation | 4 | LEU A 24THR A 13ILE A 58GLY A 52 | None | 0.85A | 4l39B-5xs9A:undetectable | 4l39B-5xs9A:9.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S21 (Trichomonasvaginalis) |
PF01249(Ribosomal_S21e) | 4 | LEU V 61TYR V 57ARG V 22THR V 20 | U 2 890 ( 4.3A)NoneNoneNone | 0.89A | 4l39B-5xyiV:undetectable | 4l39B-5xyiV:9.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ape | BIFUNCTIONAL PROTEINFOLD (Helicobacterpylori) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | THR A 145ILE A 233THR A 260GLY A 265 | None | 0.92A | 4l39B-6apeA:undetectable | 4l39B-6apeA:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bk5 | UBIQUITIN LIGASE CBL (Salpingoecarosetta) |
no annotation | 4 | LEU A 317THR A 290THR A 298GLY A 287 | None | 0.91A | 4l39B-6bk5A:undetectable | 4l39B-6bk5A:9.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bkp | HEMAGGLUTININ (Influenza Avirus) |
no annotation | 4 | LEU A 194TYR A 195ILE A 252GLY A 134 | None | 0.84A | 4l39B-6bkpA:undetectable | 4l39B-6bkpA:11.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d8w | HEMAGGLUTININ (Influenza Avirus) |
no annotation | 4 | LEU A 193TYR A 194ILE A 251GLY A 133 | OXM A 502 (-4.9A)NoneNoneNone | 0.92A | 4l39B-6d8wA:undetectable | 4l39B-6d8wA:8.09 |