SIMILAR PATTERNS OF AMINO ACIDS FOR 4KUO_A_RBFA500_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d06 NITROGEN FIXATION
REGULATORY PROTEIN
FIXL

(Sinorhizobium
meliloti) 		PF00989
(PAS) 		5 VAL A 151
SER A 153
ASN A 181
ARG A 183
LEU A 198
 HEM  A 501 (-4.3A)
HEM  A 501 ( 4.1A)
None
None
HEM  A 501 (-4.9A)
 0.84A 4kuoA-1d06A:
11.2		 4kuoA-1d06A:
29.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jnu PHY3 PROTEIN

(Adiantum
capillus-veneris) 		PF13426
(PAS_9) 		9 VAL A 932
ASN A 941
ASN A 965
CYH A 966
ARG A 967
GLN A 970
ASN A 998
ASN A1008
GLN A1029
 None
FMN  A1033 ( 4.4A)
FMN  A1033 (-3.2A)
FMN  A1033 (-1.8A)
FMN  A1033 (-3.6A)
FMN  A1033 (-3.1A)
FMN  A1033 (-3.2A)
FMN  A1033 (-4.1A)
FMN  A1033 (-4.2A)
 0.58A 4kuoA-1jnuA:
19.9		 4kuoA-1jnuA:
34.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1la2 MYO-INOSITOL-1-PHOSP
HATE SYNTHASE

(Saccharomyces
cerevisiae) 		PF01658
(Inos-1-P_synth)
PF07994
(NAD_binding_5) 		5 SER A 161
ASN A  76
ASN A 355
ASN A 200
ASN A 151
 None
NAD  A 900 (-3.3A)
NAD  A 900 (-4.0A)
None
None
 1.47A 4kuoA-1la2A:
undetectable		 4kuoA-1la2A:
14.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1n9l PUTATIVE BLUE LIGHT
RECEPTOR

(Chlamydomonas
reinhardtii) 		PF13426
(PAS_9) 		9 VAL A  23
ASN A  56
CYH A  57
ARG A  58
GLN A  61
ASN A  89
ASN A  99
LEU A 101
GLN A 120
 None
FMN  A 500 (-2.9A)
FMN  A 500 (-3.4A)
FMN  A 500 (-4.0A)
FMN  A 500 (-3.3A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.7A)
 0.41A 4kuoA-1n9lA:
19.2		 4kuoA-1n9lA:
36.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2btw ALR0975 PROTEIN

(Nostoc sp. PCC
7120) 		PF05023
(Phytochelatin) 		5 VAL A 139
SER A 238
ASN A 165
ASN A 159
GLN A 155
 None
 1.46A 4kuoA-2btwA:
undetectable		 4kuoA-2btwA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mwg BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF01740
(STAS)
PF13426
(PAS_9) 		7 ASN A  61
GLN A  66
LEU A  82
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 FMN  A 900 (-2.0A)
FMN  A 900 (-2.6A)
FMN  A 900 ( 4.8A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.87A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mwg BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF01740
(STAS)
PF13426
(PAS_9) 		5 VAL A  28
ASN A  37
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 900 ( 4.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.60A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mwg BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF01740
(STAS)
PF13426
(PAS_9) 		5 VAL A  28
ASN A  61
CYH A  62
ASN A 104
LEU A 106
 None
FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
 1.38A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mwg BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF01740
(STAS)
PF13426
(PAS_9) 		8 VAL A  28
ASN A  61
CYH A  62
GLN A  66
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 900 (-2.0A)
FMN  A 900 (-3.3A)
FMN  A 900 (-2.6A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.3A)
FMN  A 900 (-4.2A)
 0.79A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mwg BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF01740
(STAS)
PF13426
(PAS_9) 		6 VAL A  28
CYH A  62
ARG A  63
ASN A  94
ASN A 104
GLN A 123
 None
FMN  A 900 (-3.3A)
FMN  A 900 (-4.9A)
FMN  A 900 (-2.9A)
FMN  A 900 (-3.9A)
FMN  A 900 (-4.2A)
 1.19A 4kuoA-2mwgA:
15.3		 4kuoA-2mwgA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paa PHOSPHOGLYCERATE
KINASE, TESTIS
SPECIFIC

(Mus musculus) 		PF00162
(PGK) 		5 VAL A  58
SER A  56
CYH A 107
GLN A 105
LEU A  95
 None
 1.48A 4kuoA-2paaA:
undetectable		 4kuoA-2paaA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paa PHOSPHOGLYCERATE
KINASE, TESTIS
SPECIFIC

(Mus musculus) 		PF00162
(PGK) 		5 VAL A  58
SER A 114
CYH A 107
GLN A 105
LEU A  95
 None
 1.21A 4kuoA-2paaA:
undetectable		 4kuoA-2paaA:
15.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2pr5 BLUE-LIGHT
PHOTORECEPTOR

(Bacillus
subtilis) 		PF13426
(PAS_9) 		11 VAL A  28
ASN A  37
ASN A  61
CYH A  62
ARG A  63
GLN A  66
LEU A  82
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 500 (-3.8A)
FMN  A 500 (-3.2A)
FMN  A 500 (-3.5A)
FMN  A 500 (-3.8A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
 0.50A 4kuoA-2pr5A:
17.2		 4kuoA-2pr5A:
33.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ral SERINE-ASPARTATE
REPEAT-CONTAINING
PROTEIN G

(Staphylococcus
epidermidis) 		PF10425
(SdrG_C_C) 		5 VAL A 559
ASN A 428
GLN A 425
ASN A 501
GLN A 451
 None
 1.44A 4kuoA-2ralA:
undetectable		 4kuoA-2ralA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgh RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE SUBUNIT

(Homo sapiens) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC) 		5 LEU A 171
ASN A 452
ASN A 613
LEU A 611
GLN A 506
 None
 1.40A 4kuoA-2wghA:
undetectable		 4kuoA-2wghA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgh RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE SUBUNIT

(Homo sapiens) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC) 		5 LEU A 193
ASN A 452
ASN A 613
LEU A 611
GLN A 506
 None
 1.45A 4kuoA-2wghA:
undetectable		 4kuoA-2wghA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wkp NPH1-1, RAS-RELATED
C3 BOTULINUM TOXIN
SUBSTRATE 1

(Avena sativa;
Homo sapiens) 		PF00071
(Ras)
PF13426
(PAS_9) 		8 VAL A 416
ASN A 425
ASN A 449
ARG A 451
GLN A 454
ASN A 482
ASN A 492
GLN A 513
 None
FMN  A1725 (-3.8A)
FMN  A1725 (-3.0A)
FMN  A1725 (-3.8A)
FMN  A1725 (-3.1A)
FMN  A1725 (-3.0A)
FMN  A1725 (-3.8A)
FMN  A1725 (-3.8A)
 0.59A 4kuoA-2wkpA:
17.9		 4kuoA-2wkpA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wkp NPH1-1, RAS-RELATED
C3 BOTULINUM TOXIN
SUBSTRATE 1

(Avena sativa;
Homo sapiens) 		PF00071
(Ras)
PF13426
(PAS_9) 		7 VAL A 416
ASN A 449
CYH A 450
ARG A 451
GLN A 454
ASN A 492
GLN A 513
 None
FMN  A1725 (-3.0A)
FMN  A1725 (-3.4A)
FMN  A1725 (-3.8A)
FMN  A1725 (-3.1A)
FMN  A1725 (-3.8A)
FMN  A1725 (-3.8A)
 0.92A 4kuoA-2wkpA:
17.9		 4kuoA-2wkpA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		5 VAL A 376
GLN A 358
LEU A 318
LEU A 276
GLN A 330
 None
 1.13A 4kuoA-2yeqA:
undetectable		 4kuoA-2yeqA:
13.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2z6c PHOTOTROPIN-1

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		8 SER A 202
ASN A 233
ARG A 235
GLN A 238
LEU A 254
ASN A 266
LEU A 278
GLN A 297
 FMN  A 500 (-3.6A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.7A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.6A)
 0.74A 4kuoA-2z6cA:
16.8		 4kuoA-2z6cA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2z6c PHOTOTROPIN-1

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		10 VAL A 200
ASN A 233
CYH A 234
ARG A 235
GLN A 238
LEU A 254
ASN A 266
ASN A 276
LEU A 278
GLN A 297
 None
FMN  A 500 (-3.0A)
FMN  A 500 (-3.4A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.7A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.6A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.6A)
 0.62A 4kuoA-2z6cA:
16.8		 4kuoA-2z6cA:
38.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2z6d PHOTOTROPIN-2

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		8 SER A 138
ASN A 169
ARG A 171
GLN A 174
ASN A 202
ASN A 212
LEU A 214
GLN A 233
 FMN  A 500 (-3.6A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.7A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.8A)
 0.67A 4kuoA-2z6dA:
18.8		 4kuoA-2z6dA:
36.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2z6d PHOTOTROPIN-2

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		9 VAL A 136
ASN A 169
CYH A 170
ARG A 171
GLN A 174
ASN A 202
ASN A 212
LEU A 214
GLN A 233
 None
FMN  A 500 (-3.0A)
FMN  A 500 (-3.5A)
FMN  A 500 (-3.7A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.3A)
FMN  A 500 (-3.8A)
 0.40A 4kuoA-2z6dA:
18.8		 4kuoA-2z6dA:
36.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayt PUTATIVE
UNCHARACTERIZED
PROTEIN TTHB071

(Thermus
thermophilus) 		PF01261
(AP_endonuc_2) 		5 VAL A 168
SER A 170
ASN A 137
ASN A 189
LEU A 206
 None
 1.03A 4kuoA-3aytA:
undetectable		 4kuoA-3aytA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d5p PUTATIVE GLUCAN
SYNTHESIS REGULATOR
OF SMI1/KNR4 FAMILY

(Bacteroides
fragilis) 		PF09346
(SMI1_KNR4) 		5 VAL A  22
ASN A  65
LEU A  91
ASN A  42
LEU A  38
 None
 0.89A 4kuoA-3d5pA:
undetectable		 4kuoA-3d5pA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7n NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae) 		PF11715
(Nup160) 		5 ASN A  94
GLN A 477
ASN A 480
ASN A  10
LEU A  12
 None
 1.41A 4kuoA-3h7nA:
undetectable		 4kuoA-3h7nA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmm UNCHARACTERIZED
PROTEIN

(Corynebacterium
diphtheriae) 		PF04326
(AlbA_2)
PF13749
(HATPase_c_4) 		5 VAL A 401
SER A 335
ASN A 307
GLN A 372
ASN A 351
 None
 1.49A 4kuoA-3lmmA:
undetectable		 4kuoA-3lmmA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p7n SENSOR HISTIDINE
KINASE

(Erythrobacter
litoralis) 		PF00196
(GerE)
PF13426
(PAS_9) 		9 VAL A  41
SER A  43
ASN A  50
ASN A  74
CYH A  75
ARG A  76
ASN A 107
ASN A 117
GLN A 138
 None
FMN  A 500 (-3.4A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.3A)
FMN  A 500 (-3.8A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.9A)
 0.49A 4kuoA-3p7nA:
18.9		 4kuoA-3p7nA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p7n SENSOR HISTIDINE
KINASE

(Erythrobacter
litoralis) 		PF00196
(GerE)
PF13426
(PAS_9) 		5 VAL A  41
SER A  43
ASN A  50
CYH A  75
ASN A 117
 None
FMN  A 500 (-3.4A)
FMN  A 500 (-3.9A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.1A)
 1.05A 4kuoA-3p7nA:
18.9		 4kuoA-3p7nA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p7n SENSOR HISTIDINE
KINASE

(Erythrobacter
litoralis) 		PF00196
(GerE)
PF13426
(PAS_9) 		5 VAL A 121
ASN A 117
ASN A 107
ASN A  74
LEU A  52
 FMN  A 500 (-4.5A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.1A)
None
 1.49A 4kuoA-3p7nA:
18.9		 4kuoA-3p7nA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3rh8 VIVID PAS PROTEIN
VVD

(Neurospora
crassa) 		PF13426
(PAS_9) 		5 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.32A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3rh8 VIVID PAS PROTEIN
VVD

(Neurospora
crassa) 		PF13426
(PAS_9) 		8 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.59A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3rh8 VIVID PAS PROTEIN
VVD

(Neurospora
crassa) 		PF13426
(PAS_9) 		6 SER B 178
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.06A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3t50 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE

(Brucella
melitensis) 		PF13426
(PAS_9) 		8 ASN A  44
ASN A  68
ARG A  70
GLN A  73
ASN A 101
ASN A 111
LEU A 113
GLN A 132
 FMN  A 200 (-4.0A)
FMN  A 200 (-3.1A)
FMN  A 200 (-3.9A)
FMN  A 200 (-3.1A)
FMN  A 200 (-3.1A)
FMN  A 200 (-3.8A)
FMN  A 200 (-4.3A)
FMN  A 200 (-3.9A)
 0.45A 4kuoA-3t50A:
19.6		 4kuoA-3t50A:
39.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3t50 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE

(Brucella
melitensis) 		PF13426
(PAS_9) 		7 ASN A  68
CYH A  69
ARG A  70
GLN A  73
ASN A 111
LEU A 113
GLN A 132
 FMN  A 200 (-3.1A)
FMN  A 200 (-3.4A)
FMN  A 200 (-3.9A)
FMN  A 200 (-3.1A)
FMN  A 200 (-3.8A)
FMN  A 200 (-4.3A)
FMN  A 200 (-3.9A)
 0.78A 4kuoA-3t50A:
19.6		 4kuoA-3t50A:
39.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ue6 AUREOCHROME1

(Vaucheria
frigida) 		PF13426
(PAS_9) 		8 VAL A 220
ASN A 229
ASN A 253
ARG A 255
GLN A 258
ASN A 286
ASN A 296
GLN A 317
 None
FMN  A 500 (-3.9A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.3A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.57A 4kuoA-3ue6A:
19.5		 4kuoA-3ue6A:
35.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ue6 AUREOCHROME1

(Vaucheria
frigida) 		PF13426
(PAS_9) 		8 VAL A 220
ASN A 229
ASN A 253
CYH A 254
ARG A 255
GLN A 258
ASN A 296
GLN A 317
 None
FMN  A 500 (-3.9A)
FMN  A 500 (-3.1A)
FMN  A 500 (-3.5A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.1A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.1A)
 0.80A 4kuoA-3ue6A:
19.5		 4kuoA-3ue6A:
35.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ees PHOTOTROPIN-2

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		9 VAL A 392
ASN A 401
ASN A 425
ARG A 427
GLN A 430
ASN A 458
ASN A 468
LEU A 470
GLN A 489
 None
FMN  A1001 (-3.8A)
FMN  A1001 (-3.0A)
FMN  A1001 (-3.8A)
FMN  A1001 (-3.2A)
FMN  A1001 (-3.0A)
FMN  A1001 (-3.9A)
FMN  A1001 (-4.2A)
FMN  A1001 (-3.9A)
 0.49A 4kuoA-4eesA:
20.1		 4kuoA-4eesA:
34.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gcz BLUE-LIGHT
PHOTORECEPTOR,
SENSOR PROTEIN FIXL

(Bacillus
subtilis;
Bradyrhizobium
diazoefficiens) 		PF00512
(HisKA)
PF02518
(HATPase_c)
PF13426
(PAS_9) 		10 VAL A  28
ASN A  37
ASN A  61
ARG A  63
GLN A  66
LEU A  82
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 401 (-4.1A)
FMN  A 401 (-3.1A)
FMN  A 401 (-3.9A)
FMN  A 401 (-3.2A)
FMN  A 401 (-4.5A)
FMN  A 401 (-3.1A)
FMN  A 401 (-3.7A)
FMN  A 401 (-4.3A)
FMN  A 401 (-3.8A)
 0.39A 4kuoA-4gczA:
17.8		 4kuoA-4gczA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gcz BLUE-LIGHT
PHOTORECEPTOR,
SENSOR PROTEIN FIXL

(Bacillus
subtilis;
Bradyrhizobium
diazoefficiens) 		PF00512
(HisKA)
PF02518
(HATPase_c)
PF13426
(PAS_9) 		10 VAL A  28
ASN A  61
CYH A  62
ARG A  63
GLN A  66
LEU A  82
ASN A  94
ASN A 104
LEU A 106
GLN A 123
 None
FMN  A 401 (-3.1A)
FMN  A 401 (-3.3A)
FMN  A 401 (-3.9A)
FMN  A 401 (-3.2A)
FMN  A 401 (-4.5A)
FMN  A 401 (-3.1A)
FMN  A 401 (-3.7A)
FMN  A 401 (-4.3A)
FMN  A 401 (-3.8A)
 0.64A 4kuoA-4gczA:
17.8		 4kuoA-4gczA:
17.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hhd PHOTOTROPIN-1

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		8 VAL A 478
ASN A 487
ASN A 511
ARG A 513
GLN A 516
ASN A 544
ASN A 554
GLN A 575
 None
FMN  A 701 (-3.7A)
FMN  A 701 (-2.9A)
FMN  A 701 (-2.6A)
FMN  A 701 (-3.3A)
FMN  A 701 (-2.8A)
FMN  A 701 (-3.8A)
FMN  A 701 (-3.6A)
 0.70A 4kuoA-4hhdA:
19.3		 4kuoA-4hhdA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hhd PHOTOTROPIN-1

(Arabidopsis
thaliana) 		PF13426
(PAS_9) 		8 VAL A 478
ASN A 487
ASN A 511
CYH A 512
ARG A 513
GLN A 516
ASN A 554
GLN A 575
 None
FMN  A 701 (-3.7A)
FMN  A 701 (-2.9A)
FMN  A 701 (-3.7A)
FMN  A 701 (-2.6A)
FMN  A 701 (-3.3A)
FMN  A 701 (-3.8A)
FMN  A 701 (-3.6A)
 0.89A 4kuoA-4hhdA:
19.3		 4kuoA-4hhdA:
32.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hj3 LOV PROTEIN

(Rhodobacter
sphaeroides) 		PF13426
(PAS_9) 		9 ASN A  54
CYH A  55
ARG A  56
GLN A  59
LEU A  75
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 FMN  A 201 (-3.1A)
FMN  A 201 (-3.7A)
FMN  A 201 (-3.4A)
FMN  A 201 (-3.6A)
FMN  A 201 ( 4.7A)
FMN  A 201 (-2.9A)
FMN  A 201 (-3.8A)
FMN  A 201 (-4.4A)
FMN  A 201 (-3.8A)
 0.78A 4kuoA-4hj3A:
15.0		 4kuoA-4hj3A:
29.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iug BETA-GALACTOSIDASE A

(Aspergillus
oryzae) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		5 ASN A 989
ARG A 953
ASN A 956
ASN A 926
GLN A 995
 None
 1.41A 4kuoA-4iugA:
undetectable		 4kuoA-4iugA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4i RYANODINE RECEPTOR 2

(Mus musculus) 		PF01365
(RYDR_ITPR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		5 VAL A 452
ASN A 427
ARG A 504
LEU A 497
LEU A 533
 None
 1.39A 4kuoA-4l4iA:
undetectable		 4kuoA-4l4iA:
15.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4r38 BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2

(Erythrobacter
litoralis) 		PF13426
(PAS_9) 		8 ASN A  54
CYH A  55
ARG A  56
GLN A  59
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 RBF  A 201 (-2.6A)
RBF  A 201 (-3.3A)
RBF  A 201 (-3.7A)
RBF  A 201 (-3.0A)
RBF  A 201 (-2.4A)
RBF  A 201 (-3.7A)
RBF  A 201 (-4.2A)
RBF  A 201 (-4.0A)
 0.35A 4kuoA-4r38A:
18.6		 4kuoA-4r38A:
36.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r3a BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2

(Erythrobacter
litoralis) 		PF07568
(HisKA_2)
PF13426
(PAS_9)
PF13581
(HATPase_c_2) 		8 ASN A  54
CYH A  55
ARG A  56
GLN A  59
ASN A  87
ASN A  97
LEU A  99
GLN A 118
 RBF  A 402 (-2.9A)
RBF  A 402 (-3.4A)
RBF  A 402 (-3.6A)
RBF  A 402 (-3.3A)
RBF  A 402 (-2.3A)
RBF  A 402 (-4.0A)
RBF  A 402 (-4.3A)
RBF  A 402 (-4.3A)
 0.35A 4kuoA-4r3aA:
14.7		 4kuoA-4r3aA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4us5 LUCIFERASE-LIKE
MONOOXYGENASE

(Streptomyces
bottropensis) 		PF00296
(Bac_luciferase) 		5 VAL A 309
SER A 220
LEU A 167
ASN A  50
GLN A   8
 NA  A1340 (-3.7A)
None
None
None
NA  A1340 (-3.2A)
 0.97A 4kuoA-4us5A:
undetectable		 4kuoA-4us5A:
17.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY

(Trichoderma
reesei) 		PF13426
(PAS_9) 		7 ASN A 134
CYH A 135
ARG A 136
GLN A 139
ASN A 173
ASN A 183
GLN A 204
 FMN  A5201 (-2.5A)
FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.7A)
 0.71A 4kuoA-4wujA:
16.2		 4kuoA-4wujA:
35.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmm NUCLEOPORIN NUP120

(Saccharomyces
cerevisiae) 		no annotation 5 ASN E  94
GLN E 477
ASN E 480
ASN E  10
LEU E  12
 None
 1.46A 4kuoA-4xmmE:
undetectable		 4kuoA-4xmmE:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a01 O-GLYCOSYLTRANSFERAS
E

(Drosophila
melanogaster) 		PF13374
(TPR_10)
PF13414
(TPR_11)
PF13844
(Glyco_transf_41) 		5 ASN A 649
ARG A 675
ASN A 666
LEU A 664
GLN A 687
 None
 1.36A 4kuoA-5a01A:
undetectable		 4kuoA-5a01A:
10.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a8b PTAUREO1A LOV2
DOMAIN

(Phaeodactylum
tricornutum) 		PF13426
(PAS_9) 		8 VAL A 253
ASN A 262
ASN A 286
ARG A 288
GLN A 291
ASN A 319
ASN A 329
GLN A 350
 None
FMN  A 500 (-3.8A)
FMN  A 500 (-3.2A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.9A)
 0.60A 4kuoA-5a8bA:
18.5		 4kuoA-5a8bA:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a8b PTAUREO1A LOV2
DOMAIN

(Phaeodactylum
tricornutum) 		PF13426
(PAS_9) 		7 VAL A 253
ASN A 262
ASN A 286
CYH A 287
ARG A 288
GLN A 291
GLN A 350
 None
FMN  A 500 (-3.8A)
FMN  A 500 (-3.2A)
FMN  A 500 (-3.6A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.0A)
FMN  A 500 (-3.9A)
 0.81A 4kuoA-5a8bA:
18.5		 4kuoA-5a8bA:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a8b PTAUREO1A LOV2
DOMAIN

(Phaeodactylum
tricornutum) 		PF13426
(PAS_9) 		5 VAL A 253
ASN A 262
ASN A 286
CYH A 287
ASN A 319
 None
FMN  A 500 (-3.8A)
FMN  A 500 (-3.2A)
FMN  A 500 (-3.6A)
FMN  A 500 (-3.0A)
 1.35A 4kuoA-5a8bA:
18.5		 4kuoA-5a8bA:
36.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bjx WLAL PROTEIN

(Campylobacter
jejuni) 		no annotation 5 VAL A 426
ASN A 551
CYH A 428
ARG A 430
LEU A 414
 None
 1.47A 4kuoA-5bjxA:
undetectable		 4kuoA-5bjxA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		5 VAL A 353
ASN A 357
CYH A 437
ARG A 420
LEU A 413
 None
 1.44A 4kuoA-5bnzA:
undetectable		 4kuoA-5bnzA:
12.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dju NPH1-2

(Avena sativa) 		PF13426
(PAS_9) 		8 VAL A 416
ASN A 425
ASN A 449
ARG A 451
GLN A 454
ASN A 482
ASN A 492
GLN A 513
 None
FMN  A 601 ( 3.9A)
FMN  A 601 ( 3.1A)
FMN  A 601 ( 3.8A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.1A)
FMN  A 601 (-3.9A)
FMN  A 601 (-3.8A)
 0.59A 4kuoA-5djuA:
17.3		 4kuoA-5djuA:
30.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dkk LOV DOMAIN

(Phaeodactylum
tricornutum) 		PF13426
(PAS_9) 		8 VAL A 253
ASN A 262
ASN A 286
ARG A 288
GLN A 291
ASN A 319
ASN A 329
GLN A 350
 None
FMN  A 401 (-3.7A)
FMN  A 401 (-3.0A)
FMN  A 401 (-4.1A)
FMN  A 401 (-2.8A)
FMN  A 401 (-3.0A)
FMN  A 401 (-4.1A)
FMN  A 401 (-3.8A)
 0.69A 4kuoA-5dkkA:
18.5		 4kuoA-5dkkA:
36.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dkk LOV DOMAIN

(Phaeodactylum
tricornutum) 		PF13426
(PAS_9) 		8 VAL A 253
ASN A 262
ASN A 286
CYH A 287
ARG A 288
GLN A 291
ASN A 329
GLN A 350
 None
FMN  A 401 (-3.7A)
FMN  A 401 (-3.0A)
FMN  A 401 (-3.4A)
FMN  A 401 (-4.1A)
FMN  A 401 (-2.8A)
FMN  A 401 (-4.1A)
FMN  A 401 (-3.8A)
 0.86A 4kuoA-5dkkA:
18.5		 4kuoA-5dkkA:
36.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dkk LOV DOMAIN

(Phaeodactylum
tricornutum) 		PF13426
(PAS_9) 		5 VAL A 253
ASN A 262
ASN A 286
CYH A 287
ASN A 319
 None
FMN  A 401 (-3.7A)
FMN  A 401 (-3.0A)
FMN  A 401 (-3.4A)
FMN  A 401 (-3.0A)
 1.30A 4kuoA-5dkkA:
18.5		 4kuoA-5dkkA:
36.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzh RAS-RELATED C3
BOTULINUM TOXIN
SUBSTRATE
1,NPH1-1,RAS-RELATED
C3 BOTULINUM TOXIN
SUBSTRATE 1

(Avena sativa;
Homo sapiens) 		PF00071
(Ras)
PF13426
(PAS_9) 		8 VAL A  63
ASN A  72
ASN A  96
ARG A  98
GLN A 101
ASN A 129
ASN A 139
GLN A 160
 None
FMN  A 402 (-3.8A)
FMN  A 402 (-3.2A)
FMN  A 402 (-3.3A)
FMN  A 402 (-2.9A)
FMN  A 402 (-2.9A)
FMN  A 402 (-4.2A)
FMN  A 402 (-3.6A)
 0.47A 4kuoA-5hzhA:
17.6		 4kuoA-5hzhA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzk INTERSECTIN-1,NPH1-1
,INTERSECTIN-1

(Avena sativa;
Homo sapiens) 		PF00621
(RhoGEF)
PF13426
(PAS_9)
PF16652
(PH_13) 		8 VAL B1321
ASN B1330
ASN B1354
ARG B1356
GLN B1359
ASN B1387
ASN B1397
GLN B1418
 None
FMN  B1801 (-4.1A)
FMN  B1801 (-3.0A)
FMN  B1801 (-3.9A)
FMN  B1801 (-3.0A)
FMN  B1801 (-3.0A)
FMN  B1801 (-4.2A)
FMN  B1801 (-3.7A)
 0.59A 4kuoA-5hzkB:
17.8		 4kuoA-5hzkB:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzk INTERSECTIN-1,NPH1-1
,INTERSECTIN-1

(Avena sativa;
Homo sapiens) 		PF00621
(RhoGEF)
PF13426
(PAS_9)
PF16652
(PH_13) 		6 VAL B1321
ASN B1354
CYH B1355
ARG B1356
GLN B1359
GLN B1418
 None
FMN  B1801 (-3.0A)
FMN  B1801 (-3.5A)
FMN  B1801 (-3.9A)
FMN  B1801 (-3.0A)
FMN  B1801 (-3.7A)
 0.97A 4kuoA-5hzkB:
17.8		 4kuoA-5hzkB:
16.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j3w SENSORY BOX PROTEIN

(Pseudomonas
putida) 		PF13426
(PAS_9) 		8 VAL A  19
CYH A  53
ARG A  54
GLN A  57
ASN A  85
ASN A  95
LEU A  97
GLN A 116
 None
FMN  A 500 (-3.6A)
FMN  A 500 (-3.5A)
FMN  A 500 (-4.0A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.3A)
FMN  A 500 (-4.2A)
FMN  A 500 (-4.5A)
 0.67A 4kuoA-5j3wA:
16.2		 4kuoA-5j3wA:
30.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5svw ADAGIO PROTEIN 1

(Arabidopsis
thaliana) 		no annotation 8 ASN B  53
CYH B  54
ARG B  55
GLN B  58
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-2.9A)
FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.91A 4kuoA-5svwB:
16.8		 4kuoA-5svwB:
33.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tus RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE SUBUNIT

(Homo sapiens) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		5 LEU A 193
ASN A 452
ASN A 613
LEU A 611
GLN A 506
 None
 1.46A 4kuoA-5tusA:
undetectable		 4kuoA-5tusA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ygu DIAMINOPIMELATE
EPIMERASE

(Escherichia
coli) 		no annotation 5 VAL A 206
ASN A  11
GLN A  72
LEU A 247
ASN A 157
 None
IOD  A 308 (-4.5A)
TLA  A 301 (-3.2A)
None
TLA  A 301 (-3.4A)
 1.37A 4kuoA-5yguA:
undetectable		 4kuoA-5yguA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR

(Dinoroseobacter
shibae) 		no annotation 5 VAL A  38
ASN A  71
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 1.17A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR

(Dinoroseobacter
shibae) 		no annotation 7 VAL A  38
SER A  40
ASN A  47
ASN A  71
ARG A  73
GLN A  76
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.5A)
FMN  A 500 (-4.2A)
FMN  A 500 (-3.0A)
 0.89A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR

(Dinoroseobacter
shibae) 		no annotation 10 VAL A  38
SER A  40
ASN A  47
ASN A  71
CYH A  72
ARG A  73
ASN A 104
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.5A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 0.77A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR

(Dinoroseobacter
shibae) 		no annotation 10 VAL A  38
SER A  40
ASN A  47
ASN A  71
CYH A  72
LEU A  92
ASN A 104
ASN A 114
LEU A 116
GLN A 135
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.6A)
FMN  A 500 (-3.0A)
FMN  A 500 (-4.0A)
FMN  A 500 (-4.1A)
FMN  A 500 (-3.8A)
 0.57A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR

(Dinoroseobacter
shibae) 		no annotation 7 VAL A  38
SER A  40
ASN A  47
ASN A  71
GLN A  76
LEU A  92
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 ( 3.2A)
FMN  A 500 (-4.2A)
FMN  A 500 (-4.6A)
FMN  A 500 (-3.0A)
 0.80A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbv PUTATIVE BLUE-LIGHT
PHOTORECEPTOR

(Dinoroseobacter
shibae) 		no annotation 6 VAL A  38
SER A  40
ASN A  47
CYH A  72
LEU A  92
ASN A 104
 FMN  A 500 (-4.8A)
FMN  A 500 (-3.1A)
FMN  A 500 ( 3.7A)
FMN  A 500 (-3.7A)
FMN  A 500 (-4.6A)
FMN  A 500 (-3.0A)
 1.09A 4kuoA-6gbvA:
23.6		 4kuoA-6gbvA:
undetectable