SIMILAR PATTERNS OF AMINO ACIDS FOR 4KPD_A_RISA405_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)

Filter list by:

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	6	LEU A 114 ASP A 117 ARG A 126 GLN A 185 LYS A 214 THR A 215	None	0.97A	4kpdA-1fpsA: 44.4	4kpdA-1fpsA: 64.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1fps	FARNESYL DIPHOSPHATE SYNTHASE (Gallus gallus)	PF00348 (polyprenyl_synt)	5	LEU A 114 ASP A 117 ASP A 121 ARG A 126 LYS A 214	None	0.96A	4kpdA-1fpsA: 44.4	4kpdA-1fpsA: 64.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rqj	GERANYLTRANSTRANSFER ASE (Escherichia coli)	PF00348 (polyprenyl_synt)	10	LEU A 102 ASP A 105 ASP A 111 ARG A 116 GLN A 179 LYS A 202 THR A 203 GLN A 241 ASP A 244 LYS A 258	None MG A 907 (-2.5A) MG A 909 (-2.4A) RIS A 901 (-2.7A) RIS A 901 (-3.2A) RIS A 901 (-2.5A) IPE A 900 ( 3.3A) RIS A 901 ( 3.6A) MG A 908 ( 2.7A) RIS A 901 (-2.7A)	0.32A	4kpdA-1rqjA: 31.2	4kpdA-1rqjA: 26.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rtr	GERANYLTRANSTRANSFER ASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 82 ARG A 93 GLN A 154 THR A 178	None	1.13A	4kpdA-1rtrA: 25.8	4kpdA-1rtrA: 25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rtr	GERANYLTRANSTRANSFER ASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 88 ARG A 93 GLN A 154 THR A 178	None	0.70A	4kpdA-1rtrA: 25.8	4kpdA-1rtrA: 25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1rtr	GERANYLTRANSTRANSFER ASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 88 ARG A 93 THR A 178 GLN A 215	None	0.82A	4kpdA-1rtrA: 25.8	4kpdA-1rtrA: 25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1wmw	GERANYLGERANYL DIPHOSPHATE SYNTHETASE (Thermus thermophilus)	PF00348 (polyprenyl_synt)	6	LEU A 76 ASP A 79 ASP A 83 ARG A 88 GLN A 146 GLN A 209	None	1.33A	4kpdA-1wmwA: 33.1	4kpdA-1wmwA: 27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1wy0	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Pyrococcus horikoshii)	PF00348 (polyprenyl_synt)	5	LEU A 83 ASP A 90 ARG A 95 THR A 178 GLN A 215	None	0.67A	4kpdA-1wy0A: 29.3	4kpdA-1wy0A: 27.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	5	ASP A 85 ARG A 90 LYS A 160 THR A 161 GLN A 197	None	1.41A	4kpdA-2azkA: 23.6	4kpdA-2azkA: 26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	5	ASP A 85 LYS A 160 THR A 161 GLN A 197 ASP A 200	None	1.37A	4kpdA-2azkA: 23.6	4kpdA-2azkA: 26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 81 ARG A 90 THR A 161 GLN A 197	None	1.03A	4kpdA-2azkA: 23.6	4kpdA-2azkA: 26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 85 ARG A 90 THR A 161 GLN A 197	None	0.83A	4kpdA-2azkA: 23.6	4kpdA-2azkA: 26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2azk	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Sulfolobus solfataricus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 85 THR A 161 GLN A 197 ASP A 200	None	0.67A	4kpdA-2azkA: 23.6	4kpdA-2azkA: 26.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2dh4	YPL069C (Saccharomyces cerevisiae)	PF00348 (polyprenyl_synt)	9	LEU A 77 ASP A 80 ASP A 84 ARG A 89 GLN A 147 LYS A 174 THR A 175 GLN A 211 ASP A 214	None MG A 341 (-2.6A) MG A 341 (-3.0A) MG A 341 ( 4.6A) None None None None None	0.60A	4kpdA-2dh4A: 26.7	4kpdA-2dh4A: 24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ftz	GERANYLTRANSTRANSFER ASE (Thermotoga maritima)	PF00348 (polyprenyl_synt)	5	LEU A 71 ASP A 74 ARG A 85 THR A 164 GLN A 198	None UNL A 273 (-3.0A) UNL A 274 (-4.1A) MLY A 163 ( 3.9A) MLY A 163 ( 3.8A)	0.85A	4kpdA-2ftzA: 25.3	4kpdA-2ftzA: 25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ftz	GERANYLTRANSTRANSFER ASE (Thermotoga maritima)	PF00348 (polyprenyl_synt)	5	LEU A 71 ASP A 80 ARG A 85 THR A 164 GLN A 198	None MLY A 223 ( 3.6A) UNL A 274 (-4.1A) MLY A 163 ( 3.9A) MLY A 163 ( 3.8A)	0.52A	4kpdA-2ftzA: 25.3	4kpdA-2ftzA: 25.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2o1o	PUTATIVE FARNESYL PYROPHOSPHATE SYNTHASE (Cryptosporidium parvum)	PF00348 (polyprenyl_synt)	8	LEU A 112 ASP A 115 ASP A 119 ARG A 124 GLN A 184 LYS A 210 THR A 211 GLN A 251	None MG A 503 (-2.5A) MG A 502 (-2.4A) RIS A 400 (-2.9A) RIS A 400 ( 3.5A) RIS A 400 (-2.8A) RIS A 400 (-3.7A) RIS A 400 (-3.1A)	0.37A	4kpdA-2o1oA: 35.8	4kpdA-2o1oA: 32.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	PF00348 (polyprenyl_synt)	6	LEU A 61 ARG A 73 GLN A 126 LYS A 151 GLN A 185 LYS A 202	None GRG A 500 (-2.9A) GRG A 500 ( 3.5A) GRG A 500 (-2.8A) GRG A 500 (-3.2A) GRG A 500 ( 2.6A)	1.28A	4kpdA-2q80A: 26.1	4kpdA-2q80A: 26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	PF00348 (polyprenyl_synt)	8	LEU A 61 ASP A 64 ASP A 68 ARG A 73 GLN A 126 LYS A 151 GLN A 185 ASP A 188	None GRG A 500 (-2.4A) MG A 400 (-2.6A) GRG A 500 (-2.9A) GRG A 500 ( 3.5A) GRG A 500 (-2.8A) GRG A 500 (-3.2A) GRG A 500 (-3.5A)	0.64A	4kpdA-2q80A: 26.1	4kpdA-2q80A: 26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2q80	GERANYLGERANYL PYROPHOSPHATE SYNTHETASE (Homo sapiens)	PF00348 (polyprenyl_synt)	6	LEU A 61 ASP A 64 ASP A 68 GLN A 126 LYS A 151 THR A 152	None GRG A 500 (-2.4A) MG A 400 (-2.6A) GRG A 500 ( 3.5A) GRG A 500 (-2.8A) GRG A 500 ( 4.6A)	0.75A	4kpdA-2q80A: 26.1	4kpdA-2q80A: 26.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aq0	GERANYL DIPHOSPHATE SYNTHASE (Arabidopsis thaliana)	PF00348 (polyprenyl_synt)	6	LEU A 104 ASP A 107 ASP A 111 ARG A 116 LYS A 193 THR A 194	None MG A1000 (-2.9A) MG A1001 (-2.8A) FPP A1002 (-2.9A) FPP A1002 (-2.5A) ISY A1003 (-4.7A)	0.67A	4kpdA-3aq0A: 26.3	4kpdA-3aq0A: 23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aqc	COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE (Micrococcus luteus)	PF00348 (polyprenyl_synt)	5	ASP B 88 LYS B 170 THR B 171 GLN B 208 ASP B 211	MG B 327 (-2.4A) 2DE B 329 (-2.5A) None None MG B 328 (-3.1A)	0.90A	4kpdA-3aqcB: 28.5	4kpdA-3aqcB: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3aqc	COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE (Micrococcus luteus)	PF00348 (polyprenyl_synt)	7	LEU B 81 ASP B 84 ASP B 88 ARG B 93 LYS B 170 THR B 171 GLN B 208	None MG B 326 (-2.6A) MG B 327 (-2.4A) 2DE B 329 (-3.8A) 2DE B 329 (-2.5A) None None	0.80A	4kpdA-3aqcB: 28.5	4kpdA-3aqcB: 24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m0g	FARNESYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	5	ASP A 87 GLN A 153 LYS A 178 THR A 179 GLN A 175	None	1.49A	4kpdA-3m0gA: 25.3	4kpdA-3m0gA: 26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m0g	FARNESYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 78 ASP A 81 GLN A 153 LYS A 178 THR A 179	None	1.37A	4kpdA-3m0gA: 25.3	4kpdA-3m0gA: 26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m0g	FARNESYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	6	LEU A 78 ASP A 87 ARG A 92 GLN A 153 LYS A 178 THR A 179	None	0.93A	4kpdA-3m0gA: 25.3	4kpdA-3m0gA: 26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m9u	FARNESYL-DIPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 86 ARG A 100 THR A 184 GLN A 221 ASP A 224	GOL A 310 ( 4.3A) None None None None	0.91A	4kpdA-3m9uA: 26.0	4kpdA-3m9uA: 24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m9u	FARNESYL-DIPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 86 ASP A 89 ARG A 100 GLN A 160 THR A 184	GOL A 310 ( 4.3A) None None None None	1.11A	4kpdA-3m9uA: 26.0	4kpdA-3m9uA: 24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3m9u	FARNESYL-DIPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 86 ASP A 89 GLN A 160 LYS A 183 THR A 184	GOL A 310 ( 4.3A) None None None None	1.27A	4kpdA-3m9uA: 26.0	4kpdA-3m9uA: 24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3mzv	DECAPRENYL DIPHOSPHATE SYNTHASE (Rhodobacter capsulatus)	PF00348 (polyprenyl_synt)	6	LEU A 90 ASP A 93 ARG A 102 LYS A 179 THR A 180 GLN A 217	None	0.81A	4kpdA-3mzvA: 26.4	4kpdA-3mzvA: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3npk	GERANYLTRANSTRANSFER ASE (Campylobacter jejuni)	PF00348 (polyprenyl_synt)	6	LEU A 75 ASP A 78 ARG A 89 GLN A 149 LYS A 172 THR A 173	None	1.27A	4kpdA-3npkA: 26.3	4kpdA-3npkA: 26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3npk	GERANYLTRANSTRANSFER ASE (Campylobacter jejuni)	PF00348 (polyprenyl_synt)	6	LEU A 75 ASP A 84 ARG A 89 GLN A 149 LYS A 172 THR A 173	None	0.92A	4kpdA-3npkA: 26.3	4kpdA-3npkA: 26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3p41	GERANYLTRANSTRANSFER ASE (Pseudomonas protegens)	PF00348 (polyprenyl_synt)	7	LEU A 80 ASP A 83 ASP A 89 ARG A 94 GLN A 157 LYS A 180 THR A 181	None MG A 297 (-2.5A) MG A 297 (-2.5A) DMA A 300 (-2.9A) DMA A 300 (-3.6A) POP A 301 ( 2.4A) None	0.47A	4kpdA-3p41A: 24.3	4kpdA-3p41A: 28.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pko	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 84 ASP A 87 ARG A 96 LYS A 174 THR A 175	None None CIT A 326 ( 4.8A) None None	0.90A	4kpdA-3pkoA: 25.4	4kpdA-3pkoA: 25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pko	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Lactobacillus brevis)	PF00348 (polyprenyl_synt)	5	LEU A 84 ASP A 91 ARG A 96 LYS A 174 THR A 175	None None CIT A 326 ( 4.8A) None None	0.90A	4kpdA-3pkoA: 25.4	4kpdA-3pkoA: 25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3q1o	GERANYLTRANSTRANSFER ASE (ISPA) (Helicobacter pylori)	PF00348 (polyprenyl_synt)	10	LEU A 89 ASP A 92 ASP A 98 ARG A 103 GLN A 163 LYS A 186 THR A 187 GLN A 225 ASP A 228 LYS A 242	DMA A 501 ( 4.8A) MG A 400 ( 2.8A) MG A 400 ( 3.2A) DMA A 501 (-3.0A) DMA A 501 (-3.6A) DMA A 501 (-3.1A) DMA A 500 (-3.4A) DMA A 501 ( 3.8A) DMA A 501 ( 3.5A) DMA A 501 (-2.7A)	0.44A	4kpdA-3q1oA: 31.4	4kpdA-3q1oA: 27.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	6	LEU A 105 ASP A 108 ARG A 117 GLN A 191 LYS A 215 LYS A 271	None MG A 381 (-2.4A) DMA A 384 (-3.0A) DMA A 384 (-3.9A) DMA A 384 (-3.0A) DMA A 384 ( 2.8A)	1.35A	4kpdA-3qqvA: 34.1	4kpdA-3qqvA: 28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	7	LEU A 105 ASP A 108 ASP A 112 ARG A 117 GLN A 191 LYS A 215 THR A 216	None MG A 381 (-2.4A) MG A 381 (-2.8A) DMA A 384 (-3.0A) DMA A 384 (-3.9A) DMA A 384 (-3.0A) DMA A 383 ( 4.0A)	0.79A	4kpdA-3qqvA: 34.1	4kpdA-3qqvA: 28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qqv	GERANYLGERANYL PYROPHOSPHATE SYNTHASE (Corynebacterium glutamicum)	PF00348 (polyprenyl_synt)	7	LEU A 105 ASP A 108 ASP A 112 ARG A 117 LYS A 215 THR A 216 GLN A 254	None MG A 381 (-2.4A) MG A 381 (-2.8A) DMA A 384 (-3.0A) DMA A 384 (-3.0A) DMA A 383 ( 4.0A) DMA A 383 (-3.2A)	0.56A	4kpdA-3qqvA: 34.1	4kpdA-3qqvA: 28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3tc1	OCTAPRENYL PYROPHOSPHATE SYNTHASE (Helicobacter pylori)	PF00348 (polyprenyl_synt)	5	LEU A 74 ASP A 77 LYS A 162 THR A 163 GLN A 197	None	0.72A	4kpdA-3tc1A: 26.2	4kpdA-3tc1A: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3tc1	OCTAPRENYL PYROPHOSPHATE SYNTHASE (Helicobacter pylori)	PF00348 (polyprenyl_synt)	5	LEU A 74 LYS A 162 THR A 163 GLN A 197 ASP A 200	None None None None MG A 500 (-2.9A)	0.49A	4kpdA-3tc1A: 26.2	4kpdA-3tc1A: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ts7	GERANYLTRANSTRANSFER ASE (Methylococcus capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 85 ASP A 94 ARG A 99 GLN A 162 THR A 186	None	0.89A	4kpdA-3ts7A: 25.0	4kpdA-3ts7A: 24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ts7	GERANYLTRANSTRANSFER ASE (Methylococcus capsulatus)	PF00348 (polyprenyl_synt)	5	LEU A 85 ASP A 94 ARG A 99 LYS A 185 THR A 186	None	0.76A	4kpdA-3ts7A: 25.0	4kpdA-3ts7A: 24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wjo	OCTAPRENYL DIPHOSPHATE SYNTHASE (Escherichia coli)	PF00348 (polyprenyl_synt)	6	LEU A 81 ARG A 93 LYS A 170 THR A 171 GLN A 208 ASP A 211	None IPE A 401 ( 4.2A) IPE A 401 ( 2.9A) IPE A 402 ( 3.8A) IPE A 402 (-3.6A) IPE A 402 ( 4.6A)	0.94A	4kpdA-3wjoA: 25.6	4kpdA-3wjoA: 26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wjo	OCTAPRENYL DIPHOSPHATE SYNTHASE (Escherichia coli)	PF00348 (polyprenyl_synt)	6	LEU A 81 ASP A 84 ARG A 93 LYS A 170 THR A 171 GLN A 208	None IPE A 401 (-2.6A) IPE A 401 ( 4.2A) IPE A 401 ( 2.9A) IPE A 402 ( 3.8A) IPE A 402 (-3.6A)	0.86A	4kpdA-3wjoA: 25.6	4kpdA-3wjoA: 26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3wjo	OCTAPRENYL DIPHOSPHATE SYNTHASE (Escherichia coli)	PF00348 (polyprenyl_synt)	6	LEU A 81 ASP A 84 ASP A 88 ARG A 93 LYS A 170 THR A 171	None IPE A 401 (-2.6A) IPE A 401 (-3.3A) IPE A 401 ( 4.2A) IPE A 401 ( 2.9A) IPE A 402 ( 3.8A)	0.85A	4kpdA-3wjoA: 25.6	4kpdA-3wjoA: 26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zou	FARNESYL PYROPHOSPHATE SYNTHASE (Pseudomonas aeruginosa)	PF00348 (polyprenyl_synt)	5	LEU A 80 ASP A 83 ASP A 89 ARG A 94 GLN A 157	None MG A1295 (-2.5A) MG A1295 (-2.4A) GPP A1297 (-3.0A) GPP A1297 (-3.7A)	0.49A	4kpdA-3zouA: 24.0	4kpdA-3zouA: 26.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3zou	FARNESYL PYROPHOSPHATE SYNTHASE (Pseudomonas aeruginosa)	PF00348 (polyprenyl_synt)	6	LEU A 80 ASP A 83 ASP A 89 ARG A 94 LYS A 180 THR A 181	None MG A1295 (-2.5A) MG A1295 (-2.4A) GPP A1297 (-3.0A) GPP A1297 (-3.0A) None	0.55A	4kpdA-3zouA: 24.0	4kpdA-3zouA: 26.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4e1e	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma cruzi)	PF00348 (polyprenyl_synt)	10	LEU A 95 ASP A 98 ASP A 102 ARG A 107 GLN A 167 LYS A 207 THR A 208 GLN A 247 ASP A 250 LYS A 264	None MG A 403 (-2.5A) MG A 403 (-2.4A) 0MW A 404 (-2.7A) 0MW A 404 (-3.7A) 0MW A 404 (-2.8A) IPE A 405 ( 4.6A) 0MW A 404 ( 3.8A) MG A 401 (-2.7A) 0MW A 404 ( 3.0A)	0.36A	4kpdA-4e1eA: 44.9	4kpdA-4e1eA: 36.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4f62	GERANYLTRANSTRANSFER ASE (Marinomonas sp. MED121)	PF00348 (polyprenyl_synt)	5	LEU A 80 ASP A 83 ASP A 89 LYS A 178 THR A 179	None	0.79A	4kpdA-4f62A: 24.0	4kpdA-4f62A: 24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4f62	GERANYLTRANSTRANSFER ASE (Marinomonas sp. MED121)	PF00348 (polyprenyl_synt)	5	LEU A 80 ASP A 83 GLN A 155 LYS A 178 THR A 179	None	0.98A	4kpdA-4f62A: 24.0	4kpdA-4f62A: 24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fp4	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	6	ASP A 86 ASP A 90 ARG A 95 GLN A 147 THR A 163 GLN A 199	UNX A 302 ( 2.6A) UNX A 302 ( 3.2A) UNX A 302 ( 4.6A) GER A 301 ( 4.7A) None None	1.07A	4kpdA-4fp4A: 20.8	4kpdA-4fp4A: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fp4	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	6	ASP A 86 ASP A 90 ARG A 95 LYS A 162 THR A 163 GLN A 199	UNX A 302 ( 2.6A) UNX A 302 ( 3.2A) UNX A 302 ( 4.6A) GER A 301 ( 4.8A) None None	1.12A	4kpdA-4fp4A: 20.8	4kpdA-4fp4A: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fp4	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 86 ASP A 90 ARG A 95 LYS A 162 THR A 163	UNL A 303 ( 4.7A) UNX A 302 ( 2.6A) UNX A 302 ( 3.2A) UNX A 302 ( 4.6A) GER A 301 ( 4.8A) None	1.00A	4kpdA-4fp4A: 20.8	4kpdA-4fp4A: 23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4gp1	POLYPRENYL SYNTHETASE (Pyrobaculum calidifontis)	PF00348 (polyprenyl_synt)	6	LEU A 82 ASP A 85 ASP A 89 ARG A 94 LYS A 184 THR A 185	None	0.95A	4kpdA-4gp1A: 28.4	4kpdA-4gp1A: 26.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4jxy	TRANS-HEXAPRENYLTRAN STRANSFERASE (Pseudoalteromonas atlantica)	PF00348 (polyprenyl_synt)	5	LEU A 81 ASP A 84 LYS A 170 THR A 171 GLN A 208	None	0.90A	4kpdA-4jxyA: 25.7	4kpdA-4jxyA: 27.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4jxy	TRANS-HEXAPRENYLTRAN STRANSFERASE (Pseudoalteromonas atlantica)	PF00348 (polyprenyl_synt)	5	LEU A 81 LYS A 170 THR A 171 GLN A 208 ASP A 211	None	0.90A	4kpdA-4jxyA: 25.7	4kpdA-4jxyA: 27.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4jzx	FARNESYL PYROPHOSPHATE SYNTHASE (Leishmania major)	PF00348 (polyprenyl_synt)	5	ASP A 98 ARG A 107 GLN A 247 ASP A 250 LYS A 264	CA A 403 (-2.5A) 476 A 402 (-2.9A) IPE A 401 (-3.7A) CA A 404 (-3.0A) 476 A 402 (-2.9A)	1.12A	4kpdA-4jzxA: 45.3	4kpdA-4jzxA: 36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4jzx	FARNESYL PYROPHOSPHATE SYNTHASE (Leishmania major)	PF00348 (polyprenyl_synt)	9	LEU A 95 ASP A 98 ASP A 102 ARG A 107 GLN A 167 LYS A 207 GLN A 247 ASP A 250 LYS A 264	None CA A 403 (-2.5A) CA A 403 (-2.5A) 476 A 402 (-2.9A) 476 A 402 (-3.5A) 476 A 402 (-2.7A) IPE A 401 (-3.7A) CA A 404 (-3.0A) 476 A 402 (-2.9A)	0.63A	4kpdA-4jzxA: 45.3	4kpdA-4jzxA: 36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4jzx	FARNESYL PYROPHOSPHATE SYNTHASE (Leishmania major)	PF00348 (polyprenyl_synt)	9	LEU A 95 ASP A 98 ASP A 102 ARG A 107 LYS A 207 THR A 208 GLN A 247 ASP A 250 LYS A 264	None CA A 403 (-2.5A) CA A 403 (-2.5A) 476 A 402 (-2.9A) 476 A 402 (-2.7A) IPE A 401 ( 3.4A) IPE A 401 (-3.7A) CA A 404 (-3.0A) 476 A 402 (-2.9A)	0.37A	4kpdA-4jzxA: 45.3	4kpdA-4jzxA: 36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4kk2	MONOTERPENE SYNTHASE FDS-5, CHLOROPLASTIC - FARNESYL DIPHOSPHATE SYNTHASE 1 CHIMERA (Artemisia spiciformis)	PF00348 (polyprenyl_synt)	5	LEU A 94 ASP A 97 ARG A 106 GLN A 165 THR A 195	None	0.77A	4kpdA-4kk2A: 40.8	4kpdA-4kk2A: 46.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4kk2	MONOTERPENE SYNTHASE FDS-5, CHLOROPLASTIC - FARNESYL DIPHOSPHATE SYNTHASE 1 CHIMERA (Artemisia spiciformis)	PF00348 (polyprenyl_synt)	5	LEU A 94 ASP A 97 ARG A 106 LYS A 194 THR A 195	None	1.00A	4kpdA-4kk2A: 40.8	4kpdA-4kk2A: 46.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4kkm	POLYPRENYL SYNTHETASE (Zymomonas mobilis)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 86 ASP A 92 ARG A 97 GLN A 159 THR A 185	None	0.69A	4kpdA-4kkmA: 26.4	4kpdA-4kkmA: 30.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4kkm	POLYPRENYL SYNTHETASE (Zymomonas mobilis)	PF00348 (polyprenyl_synt)	6	LEU A 83 ASP A 86 ASP A 92 ARG A 97 LYS A 184 THR A 185	None	1.09A	4kpdA-4kkmA: 26.4	4kpdA-4kkmA: 30.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lfe	GERANYLGERANYL DIPHOSPHATE SYNTHASE (Streptococcus uberis)	PF00348 (polyprenyl_synt)	7	LEU A 75 ASP A 78 ARG A 89 GLN A 149 LYS A 172 THR A 173 GLN A 210	IPE A 301 (-4.7A) MG A 302 (-2.5A) IPE A 301 (-2.8A) IPE A 301 ( 3.7A) IPE A 301 (-3.0A) None None	0.68A	4kpdA-4lfeA: 25.9	4kpdA-4lfeA: 25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lfe	GERANYLGERANYL DIPHOSPHATE SYNTHASE (Streptococcus uberis)	PF00348 (polyprenyl_synt)	7	LEU A 75 ASP A 78 ASP A 84 ARG A 89 GLN A 149 LYS A 172 THR A 173	IPE A 301 (-4.7A) MG A 302 (-2.5A) MG A 302 (-2.4A) IPE A 301 (-2.8A) IPE A 301 ( 3.7A) IPE A 301 (-3.0A) None	0.46A	4kpdA-4lfeA: 25.9	4kpdA-4lfeA: 25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lfe	GERANYLGERANYL DIPHOSPHATE SYNTHASE (Streptococcus uberis)	PF00348 (polyprenyl_synt)	6	LEU A 75 GLN A 149 LYS A 172 THR A 173 GLN A 210 ASP A 213	IPE A 301 (-4.7A) IPE A 301 ( 3.7A) IPE A 301 (-3.0A) None None None	0.83A	4kpdA-4lfeA: 25.9	4kpdA-4lfeA: 25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lls	GERANYLTRANSTRANSFER ASE (Roseobacter denitrificans)	PF00348 (polyprenyl_synt)	7	LEU A 77 ASP A 80 ASP A 86 ARG A 91 GLN A 153 ASP A 216 LYS A 230	None CA A 304 ( 2.9A) CA A 305 (-2.3A) GST A 302 (-2.9A) GST A 302 (-3.7A) CA A 303 (-2.9A) GST A 302 (-2.7A)	0.74A	4kpdA-4llsA: 30.3	4kpdA-4llsA: 29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lls	GERANYLTRANSTRANSFER ASE (Roseobacter denitrificans)	PF00348 (polyprenyl_synt)	9	LEU A 77 ASP A 80 ASP A 86 ARG A 91 LYS A 178 THR A 179 GLN A 213 ASP A 216 LYS A 230	None CA A 304 ( 2.9A) CA A 305 (-2.3A) GST A 302 (-2.9A) GST A 302 (-3.4A) IPE A 301 (-4.2A) IPE A 301 ( 4.1A) CA A 303 (-2.9A) GST A 302 (-2.7A)	0.69A	4kpdA-4llsA: 30.3	4kpdA-4llsA: 29.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lob	POLYPRENYL SYNTHETASE (Acinetobacter baumannii)	PF00348 (polyprenyl_synt)	5	LEU A 85 ASP A 88 LYS A 174 THR A 175 GLN A 211	None	0.84A	4kpdA-4lobA: 27.7	4kpdA-4lobA: 29.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lob	POLYPRENYL SYNTHETASE (Acinetobacter baumannii)	PF00348 (polyprenyl_synt)	5	LEU A 85 LYS A 174 THR A 175 GLN A 211 ASP A 214	None	0.87A	4kpdA-4lobA: 27.7	4kpdA-4lobA: 29.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4p0v	FARNESYL PYROPHOSPHATE SYNTHASE (Homo sapiens)	PF00348 (polyprenyl_synt)	10	LEU A 100 ASP A 103 ASP A 107 ARG A 112 GLN A 171 LYS A 200 THR A 201 GLN A 240 ASP A 243 LYS A 257	None MG A 405 (-2.5A) MG A 405 (-2.4A) ZOL A 401 ( 2.7A) ZOL A 401 ( 3.8A) ZOL A 401 (-2.7A) ZOL A 401 (-3.7A) ZOL A 401 (-3.5A) MG A 404 (-2.8A) 1WO A 402 ( 2.8A)	0.21A	4kpdA-4p0vA: 55.9	4kpdA-4p0vA: 99.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4rxe	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	7	ASP A 103 ASP A 107 GLN A 172 LYS A 212 GLN A 252 ASP A 255 LYS A 269	MG A3004 (-2.5A) MG A3004 (-2.3A) MG A3004 ( 3.8A) 3YQ A3001 (-2.9A) 3YQ A3001 ( 4.2A) MG A3003 ( 2.9A) 3YQ A3001 (-3.1A)	0.81A	4kpdA-4rxeA: 43.6	4kpdA-4rxeA: 38.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4rxe	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	9	LEU A 100 ASP A 103 ASP A 107 ARG A 112 GLN A 172 LYS A 212 THR A 213 GLN A 252 ASP A 255	3YQ A3001 ( 4.6A) MG A3004 (-2.5A) MG A3004 (-2.3A) 3YQ A3001 (-2.8A) MG A3004 ( 3.8A) 3YQ A3001 (-2.9A) 3YQ A3001 (-4.2A) 3YQ A3001 ( 4.2A) MG A3003 ( 2.9A)	0.51A	4kpdA-4rxeA: 43.6	4kpdA-4rxeA: 38.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4wk5	GERANYLTRANSTRANSFER ASE (Thermotoga neapolitana)	PF00348 (polyprenyl_synt)	5	LEU A 71 ASP A 80 ARG A 85 THR A 164 GLN A 198	None	0.68A	4kpdA-4wk5A: 24.8	4kpdA-4wk5A: 28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4wk5	GERANYLTRANSTRANSFER ASE (Thermotoga neapolitana)	PF00348 (polyprenyl_synt)	5	LEU A 71 ASP A 80 THR A 164 GLN A 198 ASP A 201	None	0.70A	4kpdA-4wk5A: 24.8	4kpdA-4wk5A: 28.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5ahu	FARNESYL PYROPHOSPHATE SYNTHASE (Trypanosoma brucei)	PF00348 (polyprenyl_synt)	10	LEU B 100 ASP B 103 ASP B 107 ARG B 112 GLN B 172 LYS B 212 THR B 213 GLN B 252 ASP B 255 LYS B 269	None MG B1370 (-2.5A) MG B1369 (-2.2A) G76 B1368 (-2.8A) G76 B1368 ( 4.1A) G76 B1368 (-2.8A) G76 B1368 (-4.2A) G76 B1368 ( 4.0A) MG B1371 ( 3.0A) G76 B1368 (-3.1A)	0.48A	4kpdA-5ahuB: 33.8	4kpdA-5ahuB: 30.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ayp	FARNESYL DIPHOSPHATE SYNTHASE (Geobacillus stearothermophilus)	PF00348 (polyprenyl_synt)	7	LEU A 83 ASP A 86 ASP A 92 ARG A 97 GLN A 160 LYS A 183 THR A 184	None	0.88A	4kpdA-5aypA: 24.3	4kpdA-5aypA: 25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e8k	GERANYLGERANYL PYROPHOSPHATE SYNTHASE 10, MITOCHONDRIAL (Arabidopsis thaliana)	PF00348 (polyprenyl_synt)	5	LEU A 88 ASP A 97 ARG A 102 LYS A 190 THR A 191	None	1.25A	4kpdA-5e8kA: 22.9	4kpdA-5e8kA: 25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5e8l	HETERODIMERIC GERANYLGERANYL PYROPHOSPHATE SYNTHASE LARGE SUBUNIT 1, CHLOROPLASTIC (Arabidopsis thaliana)	PF00348 (polyprenyl_synt)	5	LEU A 88 ASP A 91 ASP A 97 ARG A 102 GLN A 166	None	0.98A	4kpdA-5e8lA: 24.3	4kpdA-5e8lA: 25.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ARG A 91 LYS A 168 THR A 169 GLN A 206	PO4 A 501 (-4.5A) PO4 A 501 ( 4.9A) None None None	0.77A	4kpdA-5h9dA: 29.1	4kpdA-5h9dA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 82 ARG A 91 LYS A 168 THR A 169	PO4 A 501 (-4.5A) None PO4 A 501 ( 4.9A) None None	0.87A	4kpdA-5h9dA: 29.1	4kpdA-5h9dA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 ASP A 86 ARG A 91 LYS A 168 THR A 169	PO4 A 501 (-4.5A) None PO4 A 501 ( 4.9A) None None	0.80A	4kpdA-5h9dA: 29.1	4kpdA-5h9dA: 23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h9d	FARNESYL PYROPHOSPHATE SYNTHETASE (Staphylococcus aureus)	PF00348 (polyprenyl_synt)	5	LEU A 79 LYS A 168 THR A 169 GLN A 206 ASP A 209	PO4 A 501 (-4.5A) None None None None	0.95A	4kpdA-5h9dA: 29.1	4kpdA-5h9dA: 23.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5hn7	FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE (Plasmodium vivax)	PF00348 (polyprenyl_synt)	9	ASP A 126 ASP A 130 ARG A 135 GLN A 195 LYS A 243 THR A 244 GLN A 284 ASP A 287 LYS A 301	04M A 401 ( 4.0A) None 04M A 401 (-3.5A) 04M A 401 (-3.3A) 04M A 401 (-4.5A) 04M A 401 ( 3.8A) None None 04M A 401 ( 3.9A)	0.71A	4kpdA-5hn7A: 43.5	4kpdA-5hn7A: 33.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xn6	OS07G0580900 PROTEIN (Oryza sativa)	PF00348 (polyprenyl_synt)	5	LEU A 82 ASP A 85 ASP A 91 THR A 191 GLN A 228	None	1.02A	4kpdA-5xn6A: 24.6	4kpdA-5xn6A: 25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6b07	FARNESYL DIPHOSPHATE SYNTHASE (Choristoneura fumiferana)	no annotation	9	ASP A 147 ASP A 151 ARG A 156 GLN A 215 LYS A 244 THR A 245 GLN A 284 ASP A 287 LYS A 301	MG A 402 (-2.6A) MG A 402 (-2.5A) C6M A 401 (-2.7A) C6M A 401 (-3.3A) C6M A 401 (-2.6A) C6M A 401 (-3.6A) C6M A 401 (-3.7A) MG A 404 ( 2.7A) C6M A 401 (-2.9A)	0.43A	4kpdA-6b07A: 47.5	4kpdA-6b07A: 13.99

[["4KPD_A_RISA405_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 114;ASP A 117;ARG A 126;GLN A 185;LYS A 214;THR A 215","None","0.97A","4kpdA-1fpsA:44.4","4kpdA-1fpsA:64.61"],["4KPD_A_RISA405_1","1fps","Gallus gallus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A 114;ASP A 117;ASP A 121;ARG A 126;LYS A 214","None","0.96A","4kpdA-1fpsA:44.4","4kpdA-1fpsA:64.61"],["4KPD_A_RISA405_1","1rqj","Escherichia coli","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",10,"LEU A 102;ASP A 105;ASP A 111;ARG A 116;GLN A 179;LYS A 202;THR A 203;GLN A 241;ASP A 244;LYS A 258","None; MG A 907 (-2.5A); MG A 909 (-2.4A);RIS A 901 (-2.7A);RIS A 901 (-3.2A);RIS A 901 (-2.5A);IPE A 900 ( 3.3A);RIS A 901 ( 3.6A); MG A 908 ( 2.7A);RIS A 901 (-2.7A)","0.32A","4kpdA-1rqjA:31.2","4kpdA-1rqjA:26.17"],["4KPD_A_RISA405_1","1rtr","Staphylococcus aureus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  82;ARG A  93;GLN A 154;THR A 178","None","1.13A","4kpdA-1rtrA:25.8","4kpdA-1rtrA:25.71"],["4KPD_A_RISA405_1","1rtr","Staphylococcus aureus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  88;ARG A  93;GLN A 154;THR A 178","None","0.70A","4kpdA-1rtrA:25.8","4kpdA-1rtrA:25.71"],["4KPD_A_RISA405_1","1rtr","Staphylococcus aureus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  88;ARG A  93;THR A 178;GLN A 215","None","0.82A","4kpdA-1rtrA:25.8","4kpdA-1rtrA:25.71"],["4KPD_A_RISA405_1","1wmw","Thermus thermophilus","GERANYLGERANYL DIPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  76;ASP A  79;ASP A  83;ARG A  88;GLN A 146;GLN A 209","None","1.33A","4kpdA-1wmwA:33.1","4kpdA-1wmwA:27.37"],["4KPD_A_RISA405_1","1wy0","Pyrococcus horikoshii","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  83;ASP A  90;ARG A  95;THR A 178;GLN A 215","None","0.67A","4kpdA-1wy0A:29.3","4kpdA-1wy0A:27.14"],["4KPD_A_RISA405_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"ASP A  85;ARG A  90;LYS A 160;THR A 161;GLN A 197","None","1.41A","4kpdA-2azkA:23.6","4kpdA-2azkA:26.70"],["4KPD_A_RISA405_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"ASP A  85;LYS A 160;THR A 161;GLN A 197;ASP A 200","None","1.37A","4kpdA-2azkA:23.6","4kpdA-2azkA:26.70"],["4KPD_A_RISA405_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  81;ARG A  90;THR A 161;GLN A 197","None","1.03A","4kpdA-2azkA:23.6","4kpdA-2azkA:26.70"],["4KPD_A_RISA405_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  85;ARG A  90;THR A 161;GLN A 197","None","0.83A","4kpdA-2azkA:23.6","4kpdA-2azkA:26.70"],["4KPD_A_RISA405_1","2azk","Sulfolobus solfataricus","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  85;THR A 161;GLN A 197;ASP A 200","None","0.67A","4kpdA-2azkA:23.6","4kpdA-2azkA:26.70"],["4KPD_A_RISA405_1","2dh4","Saccharomyces cerevisiae","YPL069C","PF00348(polyprenyl_synt)",9,"LEU A  77;ASP A  80;ASP A  84;ARG A  89;GLN A 147;LYS A 174;THR A 175;GLN A 211;ASP A 214","None; MG A 341 (-2.6A); MG A 341 (-3.0A); MG A 341 ( 4.6A);None;None;None;None;None","0.60A","4kpdA-2dh4A:26.7","4kpdA-2dh4A:24.00"],["4KPD_A_RISA405_1","2ftz","Thermotoga maritima","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  71;ASP A  74;ARG A  85;THR A 164;GLN A 198","None;UNL A 273 (-3.0A);UNL A 274 (-4.1A);MLY A 163 ( 3.9A);MLY A 163 ( 3.8A)","0.85A","4kpdA-2ftzA:25.3","4kpdA-2ftzA:25.98"],["4KPD_A_RISA405_1","2ftz","Thermotoga maritima","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  71;ASP A  80;ARG A  85;THR A 164;GLN A 198","None;MLY A 223 ( 3.6A);UNL A 274 (-4.1A);MLY A 163 ( 3.9A);MLY A 163 ( 3.8A)","0.52A","4kpdA-2ftzA:25.3","4kpdA-2ftzA:25.98"],["4KPD_A_RISA405_1","2o1o","Cryptosporidium parvum","PUTATIVE FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",8,"LEU A 112;ASP A 115;ASP A 119;ARG A 124;GLN A 184;LYS A 210;THR A 211;GLN A 251","None; MG A 503 (-2.5A); MG A 502 (-2.4A);RIS A 400 (-2.9A);RIS A 400 ( 3.5A);RIS A 400 (-2.8A);RIS A 400 (-3.7A);RIS A 400 (-3.1A)","0.37A","4kpdA-2o1oA:35.8","4kpdA-2o1oA:32.74"],["4KPD_A_RISA405_1","2q80","Homo sapiens","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  61;ARG A  73;GLN A 126;LYS A 151;GLN A 185;LYS A 202","None;GRG A 500 (-2.9A);GRG A 500 ( 3.5A);GRG A 500 (-2.8A);GRG A 500 (-3.2A);GRG A 500 ( 2.6A)","1.28A","4kpdA-2q80A:26.1","4kpdA-2q80A:26.90"],["4KPD_A_RISA405_1","2q80","Homo sapiens","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",8,"LEU A  61;ASP A  64;ASP A  68;ARG A  73;GLN A 126;LYS A 151;GLN A 185;ASP A 188","None;GRG A 500 (-2.4A); MG A 400 (-2.6A);GRG A 500 (-2.9A);GRG A 500 ( 3.5A);GRG A 500 (-2.8A);GRG A 500 (-3.2A);GRG A 500 (-3.5A)","0.64A","4kpdA-2q80A:26.1","4kpdA-2q80A:26.90"],["4KPD_A_RISA405_1","2q80","Homo sapiens","GERANYLGERANYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  61;ASP A  64;ASP A  68;GLN A 126;LYS A 151;THR A 152","None;GRG A 500 (-2.4A); MG A 400 (-2.6A);GRG A 500 ( 3.5A);GRG A 500 (-2.8A);GRG A 500 ( 4.6A)","0.75A","4kpdA-2q80A:26.1","4kpdA-2q80A:26.90"],["4KPD_A_RISA405_1","3aq0","Arabidopsis thaliana","GERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 104;ASP A 107;ASP A 111;ARG A 116;LYS A 193;THR A 194","None; MG A1000 (-2.9A); MG A1001 (-2.8A);FPP A1002 (-2.9A);FPP A1002 (-2.5A);ISY A1003 (-4.7A)","0.67A","4kpdA-3aq0A:26.3","4kpdA-3aq0A:23.86"],["4KPD_A_RISA405_1","3aqc","Micrococcus luteus","COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"ASP B  88;LYS B 170;THR B 171;GLN B 208;ASP B 211"," MG B 327 (-2.4A);2DE B 329 (-2.5A);None;None; MG B 328 (-3.1A)","0.90A","4kpdA-3aqcB:28.5","4kpdA-3aqcB:24.40"],["4KPD_A_RISA405_1","3aqc","Micrococcus luteus","COMPONENT B OF HEXAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU B  81;ASP B  84;ASP B  88;ARG B  93;LYS B 170;THR B 171;GLN B 208","None; MG B 326 (-2.6A); MG B 327 (-2.4A);2DE B 329 (-3.8A);2DE B 329 (-2.5A);None;None","0.80A","4kpdA-3aqcB:28.5","4kpdA-3aqcB:24.40"],["4KPD_A_RISA405_1","3m0g","Rhodobacter capsulatus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"ASP A  87;GLN A 153;LYS A 178;THR A 179;GLN A 175","None","1.49A","4kpdA-3m0gA:25.3","4kpdA-3m0gA:26.23"],["4KPD_A_RISA405_1","3m0g","Rhodobacter capsulatus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  78;ASP A  81;GLN A 153;LYS A 178;THR A 179","None","1.37A","4kpdA-3m0gA:25.3","4kpdA-3m0gA:26.23"],["4KPD_A_RISA405_1","3m0g","Rhodobacter capsulatus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  78;ASP A  87;ARG A  92;GLN A 153;LYS A 178;THR A 179","None","0.93A","4kpdA-3m0gA:25.3","4kpdA-3m0gA:26.23"],["4KPD_A_RISA405_1","3m9u","Lactobacillus brevis","FARNESYL-DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  86;ARG A 100;THR A 184;GLN A 221;ASP A 224","GOL A 310 ( 4.3A);None;None;None;None","0.91A","4kpdA-3m9uA:26.0","4kpdA-3m9uA:24.62"],["4KPD_A_RISA405_1","3m9u","Lactobacillus brevis","FARNESYL-DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  86;ASP A  89;ARG A 100;GLN A 160;THR A 184","GOL A 310 ( 4.3A);None;None;None;None","1.11A","4kpdA-3m9uA:26.0","4kpdA-3m9uA:24.62"],["4KPD_A_RISA405_1","3m9u","Lactobacillus brevis","FARNESYL-DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  86;ASP A  89;GLN A 160;LYS A 183;THR A 184","GOL A 310 ( 4.3A);None;None;None;None","1.27A","4kpdA-3m9uA:26.0","4kpdA-3m9uA:24.62"],["4KPD_A_RISA405_1","3mzv","Rhodobacter capsulatus","DECAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  90;ASP A  93;ARG A 102;LYS A 179;THR A 180;GLN A 217","None","0.81A","4kpdA-3mzvA:26.4","4kpdA-3mzvA:25.91"],["4KPD_A_RISA405_1","3npk","Campylobacter jejuni","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",6,"LEU A  75;ASP A  78;ARG A  89;GLN A 149;LYS A 172;THR A 173","None","1.27A","4kpdA-3npkA:26.3","4kpdA-3npkA:26.03"],["4KPD_A_RISA405_1","3npk","Campylobacter jejuni","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",6,"LEU A  75;ASP A  84;ARG A  89;GLN A 149;LYS A 172;THR A 173","None","0.92A","4kpdA-3npkA:26.3","4kpdA-3npkA:26.03"],["4KPD_A_RISA405_1","3p41","Pseudomonas protegens","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",7,"LEU A  80;ASP A  83;ASP A  89;ARG A  94;GLN A 157;LYS A 180;THR A 181","None; MG A 297 (-2.5A); MG A 297 (-2.5A);DMA A 300 (-2.9A);DMA A 300 (-3.6A);POP A 301 ( 2.4A);None","0.47A","4kpdA-3p41A:24.3","4kpdA-3p41A:28.64"],["4KPD_A_RISA405_1","3pko","Lactobacillus brevis","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  84;ASP A  87;ARG A  96;LYS A 174;THR A 175","None;None;CIT A 326 ( 4.8A);None;None","0.90A","4kpdA-3pkoA:25.4","4kpdA-3pkoA:25.83"],["4KPD_A_RISA405_1","3pko","Lactobacillus brevis","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  84;ASP A  91;ARG A  96;LYS A 174;THR A 175","None;None;CIT A 326 ( 4.8A);None;None","0.90A","4kpdA-3pkoA:25.4","4kpdA-3pkoA:25.83"],["4KPD_A_RISA405_1","3q1o","Helicobacter pylori","GERANYLTRANSTRANSFERASE (ISPA)","PF00348(polyprenyl_synt)",10,"LEU A  89;ASP A  92;ASP A  98;ARG A 103;GLN A 163;LYS A 186;THR A 187;GLN A 225;ASP A 228;LYS A 242","DMA A 501 ( 4.8A); MG A 400 ( 2.8A); MG A 400 ( 3.2A);DMA A 501 (-3.0A);DMA A 501 (-3.6A);DMA A 501 (-3.1A);DMA A 500 (-3.4A);DMA A 501 ( 3.8A);DMA A 501 ( 3.5A);DMA A 501 (-2.7A)","0.44A","4kpdA-3q1oA:31.4","4kpdA-3q1oA:27.56"],["4KPD_A_RISA405_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A 105;ASP A 108;ARG A 117;GLN A 191;LYS A 215;LYS A 271","None; MG A 381 (-2.4A);DMA A 384 (-3.0A);DMA A 384 (-3.9A);DMA A 384 (-3.0A);DMA A 384 ( 2.8A)","1.35A","4kpdA-3qqvA:34.1","4kpdA-3qqvA:28.37"],["4KPD_A_RISA405_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A 105;ASP A 108;ASP A 112;ARG A 117;GLN A 191;LYS A 215;THR A 216","None; MG A 381 (-2.4A); MG A 381 (-2.8A);DMA A 384 (-3.0A);DMA A 384 (-3.9A);DMA A 384 (-3.0A);DMA A 383 ( 4.0A)","0.79A","4kpdA-3qqvA:34.1","4kpdA-3qqvA:28.37"],["4KPD_A_RISA405_1","3qqv","Corynebacterium glutamicum","GERANYLGERANYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A 105;ASP A 108;ASP A 112;ARG A 117;LYS A 215;THR A 216;GLN A 254","None; MG A 381 (-2.4A); MG A 381 (-2.8A);DMA A 384 (-3.0A);DMA A 384 (-3.0A);DMA A 383 ( 4.0A);DMA A 383 (-3.2A)","0.56A","4kpdA-3qqvA:34.1","4kpdA-3qqvA:28.37"],["4KPD_A_RISA405_1","3tc1","Helicobacter pylori","OCTAPRENYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  74;ASP A  77;LYS A 162;THR A 163;GLN A 197","None","0.72A","4kpdA-3tc1A:26.2","4kpdA-3tc1A:23.45"],["4KPD_A_RISA405_1","3tc1","Helicobacter pylori","OCTAPRENYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  74;LYS A 162;THR A 163;GLN A 197;ASP A 200","None;None;None;None; MG A 500 (-2.9A)","0.49A","4kpdA-3tc1A:26.2","4kpdA-3tc1A:23.45"],["4KPD_A_RISA405_1","3ts7","Methylococcus capsulatus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  85;ASP A  94;ARG A  99;GLN A 162;THR A 186","None","0.89A","4kpdA-3ts7A:25.0","4kpdA-3ts7A:24.94"],["4KPD_A_RISA405_1","3ts7","Methylococcus capsulatus","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  85;ASP A  94;ARG A  99;LYS A 185;THR A 186","None","0.76A","4kpdA-3ts7A:25.0","4kpdA-3ts7A:24.94"],["4KPD_A_RISA405_1","3wjo","Escherichia coli","OCTAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  81;ARG A  93;LYS A 170;THR A 171;GLN A 208;ASP A 211","None;IPE A 401 ( 4.2A);IPE A 401 ( 2.9A);IPE A 402 ( 3.8A);IPE A 402 (-3.6A);IPE A 402 ( 4.6A)","0.94A","4kpdA-3wjoA:25.6","4kpdA-3wjoA:26.60"],["4KPD_A_RISA405_1","3wjo","Escherichia coli","OCTAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  81;ASP A  84;ARG A  93;LYS A 170;THR A 171;GLN A 208","None;IPE A 401 (-2.6A);IPE A 401 ( 4.2A);IPE A 401 ( 2.9A);IPE A 402 ( 3.8A);IPE A 402 (-3.6A)","0.86A","4kpdA-3wjoA:25.6","4kpdA-3wjoA:26.60"],["4KPD_A_RISA405_1","3wjo","Escherichia coli","OCTAPRENYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  81;ASP A  84;ASP A  88;ARG A  93;LYS A 170;THR A 171","None;IPE A 401 (-2.6A);IPE A 401 (-3.3A);IPE A 401 ( 4.2A);IPE A 401 ( 2.9A);IPE A 402 ( 3.8A)","0.85A","4kpdA-3wjoA:25.6","4kpdA-3wjoA:26.60"],["4KPD_A_RISA405_1","3zou","Pseudomonas aeruginosa","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"LEU A  80;ASP A  83;ASP A  89;ARG A  94;GLN A 157","None; MG A1295 (-2.5A); MG A1295 (-2.4A);GPP A1297 (-3.0A);GPP A1297 (-3.7A)","0.49A","4kpdA-3zouA:24.0","4kpdA-3zouA:26.75"],["4KPD_A_RISA405_1","3zou","Pseudomonas aeruginosa","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  80;ASP A  83;ASP A  89;ARG A  94;LYS A 180;THR A 181","None; MG A1295 (-2.5A); MG A1295 (-2.4A);GPP A1297 (-3.0A);GPP A1297 (-3.0A);None","0.55A","4kpdA-3zouA:24.0","4kpdA-3zouA:26.75"],["4KPD_A_RISA405_1","4e1e","Trypanosoma cruzi","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",10,"LEU A  95;ASP A  98;ASP A 102;ARG A 107;GLN A 167;LYS A 207;THR A 208;GLN A 247;ASP A 250;LYS A 264","None; MG A 403 (-2.5A); MG A 403 (-2.4A);0MW A 404 (-2.7A);0MW A 404 (-3.7A);0MW A 404 (-2.8A);IPE A 405 ( 4.6A);0MW A 404 ( 3.8A); MG A 401 (-2.7A);0MW A 404 ( 3.0A)","0.36A","4kpdA-4e1eA:44.9","4kpdA-4e1eA:36.32"],["4KPD_A_RISA405_1","4f62","Marinomonas sp. MED121","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  80;ASP A  83;ASP A  89;LYS A 178;THR A 179","None","0.79A","4kpdA-4f62A:24.0","4kpdA-4f62A:24.43"],["4KPD_A_RISA405_1","4f62","Marinomonas sp. MED121","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  80;ASP A  83;GLN A 155;LYS A 178;THR A 179","None","0.98A","4kpdA-4f62A:24.0","4kpdA-4f62A:24.43"],["4KPD_A_RISA405_1","4fp4","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"ASP A  86;ASP A  90;ARG A  95;GLN A 147;THR A 163;GLN A 199","UNX A 302 ( 2.6A);UNX A 302 ( 3.2A);UNX A 302 ( 4.6A);GER A 301 ( 4.7A);None;None","1.07A","4kpdA-4fp4A:20.8","4kpdA-4fp4A:23.90"],["4KPD_A_RISA405_1","4fp4","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"ASP A  86;ASP A  90;ARG A  95;LYS A 162;THR A 163;GLN A 199","UNX A 302 ( 2.6A);UNX A 302 ( 3.2A);UNX A 302 ( 4.6A);GER A 301 ( 4.8A);None;None","1.12A","4kpdA-4fp4A:20.8","4kpdA-4fp4A:23.90"],["4KPD_A_RISA405_1","4fp4","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  86;ASP A  90;ARG A  95;LYS A 162;THR A 163","UNL A 303 ( 4.7A);UNX A 302 ( 2.6A);UNX A 302 ( 3.2A);UNX A 302 ( 4.6A);GER A 301 ( 4.8A);None","1.00A","4kpdA-4fp4A:20.8","4kpdA-4fp4A:23.90"],["4KPD_A_RISA405_1","4gp1","Pyrobaculum calidifontis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  82;ASP A  85;ASP A  89;ARG A  94;LYS A 184;THR A 185","None","0.95A","4kpdA-4gp1A:28.4","4kpdA-4gp1A:26.57"],["4KPD_A_RISA405_1","4jxy","Pseudoalteromonas atlantica","TRANS-HEXAPRENYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  81;ASP A  84;LYS A 170;THR A 171;GLN A 208","None","0.90A","4kpdA-4jxyA:25.7","4kpdA-4jxyA:27.32"],["4KPD_A_RISA405_1","4jxy","Pseudoalteromonas atlantica","TRANS-HEXAPRENYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  81;LYS A 170;THR A 171;GLN A 208;ASP A 211","None","0.90A","4kpdA-4jxyA:25.7","4kpdA-4jxyA:27.32"],["4KPD_A_RISA405_1","4jzx","Leishmania major","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",5,"ASP A  98;ARG A 107;GLN A 247;ASP A 250;LYS A 264"," CA A 403 (-2.5A);476 A 402 (-2.9A);IPE A 401 (-3.7A); CA A 404 (-3.0A);476 A 402 (-2.9A)","1.12A","4kpdA-4jzxA:45.3","4kpdA-4jzxA:36.97"],["4KPD_A_RISA405_1","4jzx","Leishmania major","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",9,"LEU A  95;ASP A  98;ASP A 102;ARG A 107;GLN A 167;LYS A 207;GLN A 247;ASP A 250;LYS A 264","None; CA A 403 (-2.5A); CA A 403 (-2.5A);476 A 402 (-2.9A);476 A 402 (-3.5A);476 A 402 (-2.7A);IPE A 401 (-3.7A); CA A 404 (-3.0A);476 A 402 (-2.9A)","0.63A","4kpdA-4jzxA:45.3","4kpdA-4jzxA:36.97"],["4KPD_A_RISA405_1","4jzx","Leishmania major","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",9,"LEU A  95;ASP A  98;ASP A 102;ARG A 107;LYS A 207;THR A 208;GLN A 247;ASP A 250;LYS A 264","None; CA A 403 (-2.5A); CA A 403 (-2.5A);476 A 402 (-2.9A);476 A 402 (-2.7A);IPE A 401 ( 3.4A);IPE A 401 (-3.7A); CA A 404 (-3.0A);476 A 402 (-2.9A)","0.37A","4kpdA-4jzxA:45.3","4kpdA-4jzxA:36.97"],["4KPD_A_RISA405_1","4kk2","Artemisia spiciformis","MONOTERPENE SYNTHASE FDS-5, CHLOROPLASTIC - FARNESYL DIPHOSPHATE SYNTHASE 1 CHIMERA","PF00348(polyprenyl_synt)",5,"LEU A  94;ASP A  97;ARG A 106;GLN A 165;THR A 195","None","0.77A","4kpdA-4kk2A:40.8","4kpdA-4kk2A:46.46"],["4KPD_A_RISA405_1","4kk2","Artemisia spiciformis","MONOTERPENE SYNTHASE FDS-5, CHLOROPLASTIC - FARNESYL DIPHOSPHATE SYNTHASE 1 CHIMERA","PF00348(polyprenyl_synt)",5,"LEU A  94;ASP A  97;ARG A 106;LYS A 194;THR A 195","None","1.00A","4kpdA-4kk2A:40.8","4kpdA-4kk2A:46.46"],["4KPD_A_RISA405_1","4kkm","Zymomonas mobilis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  86;ASP A  92;ARG A  97;GLN A 159;THR A 185","None","0.69A","4kpdA-4kkmA:26.4","4kpdA-4kkmA:30.40"],["4KPD_A_RISA405_1","4kkm","Zymomonas mobilis","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",6,"LEU A  83;ASP A  86;ASP A  92;ARG A  97;LYS A 184;THR A 185","None","1.09A","4kpdA-4kkmA:26.4","4kpdA-4kkmA:30.40"],["4KPD_A_RISA405_1","4lfe","Streptococcus uberis","GERANYLGERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A  75;ASP A  78;ARG A  89;GLN A 149;LYS A 172;THR A 173;GLN A 210","IPE A 301 (-4.7A); MG A 302 (-2.5A);IPE A 301 (-2.8A);IPE A 301 ( 3.7A);IPE A 301 (-3.0A);None;None","0.68A","4kpdA-4lfeA:25.9","4kpdA-4lfeA:25.74"],["4KPD_A_RISA405_1","4lfe","Streptococcus uberis","GERANYLGERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A  75;ASP A  78;ASP A  84;ARG A  89;GLN A 149;LYS A 172;THR A 173","IPE A 301 (-4.7A); MG A 302 (-2.5A); MG A 302 (-2.4A);IPE A 301 (-2.8A);IPE A 301 ( 3.7A);IPE A 301 (-3.0A);None","0.46A","4kpdA-4lfeA:25.9","4kpdA-4lfeA:25.74"],["4KPD_A_RISA405_1","4lfe","Streptococcus uberis","GERANYLGERANYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",6,"LEU A  75;GLN A 149;LYS A 172;THR A 173;GLN A 210;ASP A 213","IPE A 301 (-4.7A);IPE A 301 ( 3.7A);IPE A 301 (-3.0A);None;None;None","0.83A","4kpdA-4lfeA:25.9","4kpdA-4lfeA:25.74"],["4KPD_A_RISA405_1","4lls","Roseobacter denitrificans","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",7,"LEU A  77;ASP A  80;ASP A  86;ARG A  91;GLN A 153;ASP A 216;LYS A 230","None; CA A 304 ( 2.9A); CA A 305 (-2.3A);GST A 302 (-2.9A);GST A 302 (-3.7A); CA A 303 (-2.9A);GST A 302 (-2.7A)","0.74A","4kpdA-4llsA:30.3","4kpdA-4llsA:29.05"],["4KPD_A_RISA405_1","4lls","Roseobacter denitrificans","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",9,"LEU A  77;ASP A  80;ASP A  86;ARG A  91;LYS A 178;THR A 179;GLN A 213;ASP A 216;LYS A 230","None; CA A 304 ( 2.9A); CA A 305 (-2.3A);GST A 302 (-2.9A);GST A 302 (-3.4A);IPE A 301 (-4.2A);IPE A 301 ( 4.1A); CA A 303 (-2.9A);GST A 302 (-2.7A)","0.69A","4kpdA-4llsA:30.3","4kpdA-4llsA:29.05"],["4KPD_A_RISA405_1","4lob","Acinetobacter baumannii","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  85;ASP A  88;LYS A 174;THR A 175;GLN A 211","None","0.84A","4kpdA-4lobA:27.7","4kpdA-4lobA:29.85"],["4KPD_A_RISA405_1","4lob","Acinetobacter baumannii","POLYPRENYL SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  85;LYS A 174;THR A 175;GLN A 211;ASP A 214","None","0.87A","4kpdA-4lobA:27.7","4kpdA-4lobA:29.85"],["4KPD_A_RISA405_1","4p0v","Homo sapiens","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",10,"LEU A 100;ASP A 103;ASP A 107;ARG A 112;GLN A 171;LYS A 200;THR A 201;GLN A 240;ASP A 243;LYS A 257","None; MG A 405 (-2.5A); MG A 405 (-2.4A);ZOL A 401 ( 2.7A);ZOL A 401 ( 3.8A);ZOL A 401 (-2.7A);ZOL A 401 (-3.7A);ZOL A 401 (-3.5A); MG A 404 (-2.8A);1WO A 402 ( 2.8A)","0.21A","4kpdA-4p0vA:55.9","4kpdA-4p0vA:99.71"],["4KPD_A_RISA405_1","4rxe","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"ASP A 103;ASP A 107;GLN A 172;LYS A 212;GLN A 252;ASP A 255;LYS A 269"," MG A3004 (-2.5A); MG A3004 (-2.3A); MG A3004 ( 3.8A);3YQ A3001 (-2.9A);3YQ A3001 ( 4.2A); MG A3003 ( 2.9A);3YQ A3001 (-3.1A)","0.81A","4kpdA-4rxeA:43.6","4kpdA-4rxeA:38.08"],["4KPD_A_RISA405_1","4rxe","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",9,"LEU A 100;ASP A 103;ASP A 107;ARG A 112;GLN A 172;LYS A 212;THR A 213;GLN A 252;ASP A 255","3YQ A3001 ( 4.6A); MG A3004 (-2.5A); MG A3004 (-2.3A);3YQ A3001 (-2.8A); MG A3004 ( 3.8A);3YQ A3001 (-2.9A);3YQ A3001 (-4.2A);3YQ A3001 ( 4.2A); MG A3003 ( 2.9A)","0.51A","4kpdA-4rxeA:43.6","4kpdA-4rxeA:38.08"],["4KPD_A_RISA405_1","4wk5","Thermotoga neapolitana","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  71;ASP A  80;ARG A  85;THR A 164;GLN A 198","None","0.68A","4kpdA-4wk5A:24.8","4kpdA-4wk5A:28.53"],["4KPD_A_RISA405_1","4wk5","Thermotoga neapolitana","GERANYLTRANSTRANSFERASE","PF00348(polyprenyl_synt)",5,"LEU A  71;ASP A  80;THR A 164;GLN A 198;ASP A 201","None","0.70A","4kpdA-4wk5A:24.8","4kpdA-4wk5A:28.53"],["4KPD_A_RISA405_1","5ahu","Trypanosoma brucei","FARNESYL PYROPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",10,"LEU B 100;ASP B 103;ASP B 107;ARG B 112;GLN B 172;LYS B 212;THR B 213;GLN B 252;ASP B 255;LYS B 269","None; MG B1370 (-2.5A); MG B1369 (-2.2A);G76 B1368 (-2.8A);G76 B1368 ( 4.1A);G76 B1368 (-2.8A);G76 B1368 (-4.2A);G76 B1368 ( 4.0A); MG B1371 ( 3.0A);G76 B1368 (-3.1A)","0.48A","4kpdA-5ahuB:33.8","4kpdA-5ahuB:30.79"],["4KPD_A_RISA405_1","5ayp","Geobacillus stearothermophilus","FARNESYL DIPHOSPHATE SYNTHASE","PF00348(polyprenyl_synt)",7,"LEU A  83;ASP A  86;ASP A  92;ARG A  97;GLN A 160;LYS A 183;THR A 184","None","0.88A","4kpdA-5aypA:24.3","4kpdA-5aypA:25.85"],["4KPD_A_RISA405_1","5e8k","Arabidopsis thaliana","GERANYLGERANYL PYROPHOSPHATE SYNTHASE 10, MITOCHONDRIAL","PF00348(polyprenyl_synt)",5,"LEU A  88;ASP A  97;ARG A 102;LYS A 190;THR A 191","None","1.25A","4kpdA-5e8kA:22.9","4kpdA-5e8kA:25.89"],["4KPD_A_RISA405_1","5e8l","Arabidopsis thaliana","HETERODIMERIC GERANYLGERANYL PYROPHOSPHATE SYNTHASE LARGE SUBUNIT 1, CHLOROPLASTIC","PF00348(polyprenyl_synt)",5,"LEU A  88;ASP A  91;ASP A  97;ARG A 102;GLN A 166","None","0.98A","4kpdA-5e8lA:24.3","4kpdA-5e8lA:25.58"],["4KPD_A_RISA405_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ARG A  91;LYS A 168;THR A 169;GLN A 206","PO4 A 501 (-4.5A);PO4 A 501 ( 4.9A);None;None;None","0.77A","4kpdA-5h9dA:29.1","4kpdA-5h9dA:23.44"],["4KPD_A_RISA405_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  82;ARG A  91;LYS A 168;THR A 169","PO4 A 501 (-4.5A);None;PO4 A 501 ( 4.9A);None;None","0.87A","4kpdA-5h9dA:29.1","4kpdA-5h9dA:23.44"],["4KPD_A_RISA405_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  79;ASP A  86;ARG A  91;LYS A 168;THR A 169","PO4 A 501 (-4.5A);None;PO4 A 501 ( 4.9A);None;None","0.80A","4kpdA-5h9dA:29.1","4kpdA-5h9dA:23.44"],["4KPD_A_RISA405_1","5h9d","Staphylococcus aureus","FARNESYL PYROPHOSPHATE SYNTHETASE","PF00348(polyprenyl_synt)",5,"LEU A  79;LYS A 168;THR A 169;GLN A 206;ASP A 209","PO4 A 501 (-4.5A);None;None;None;None","0.95A","4kpdA-5h9dA:29.1","4kpdA-5h9dA:23.44"],["4KPD_A_RISA405_1","5hn7","Plasmodium vivax","FARNESYL PYROPHOSPHATE SYNTHASE, PUTATIVE","PF00348(polyprenyl_synt)",9,"ASP A 126;ASP A 130;ARG A 135;GLN A 195;LYS A 243;THR A 244;GLN A 284;ASP A 287;LYS A 301","04M A 401 ( 4.0A);None;04M A 401 (-3.5A);04M A 401 (-3.3A);04M A 401 (-4.5A);04M A 401 ( 3.8A);None;None;04M A 401 ( 3.9A)","0.71A","4kpdA-5hn7A:43.5","4kpdA-5hn7A:33.75"],["4KPD_A_RISA405_1","5xn6","Oryza sativa","OS07G0580900 PROTEIN","PF00348(polyprenyl_synt)",5,"LEU A  82;ASP A  85;ASP A  91;THR A 191;GLN A 228","None","1.02A","4kpdA-5xn6A:24.6","4kpdA-5xn6A:25.55"],["4KPD_A_RISA405_1","6b07","Choristoneura fumiferana","FARNESYL DIPHOSPHATE SYNTHASE","no annotation",9,"ASP A 147;ASP A 151;ARG A 156;GLN A 215;LYS A 244;THR A 245;GLN A 284;ASP A 287;LYS A 301"," MG A 402 (-2.6A); MG A 402 (-2.5A);C6M A 401 (-2.7A);C6M A 401 (-3.3A);C6M A 401 (-2.6A);C6M A 401 (-3.6A);C6M A 401 (-3.7A); MG A 404 ( 2.7A);C6M A 401 (-2.9A)","0.43A","4kpdA-6b07A:47.5","4kpdA-6b07A:13.99"]]