SIMILAR PATTERNS OF AMINO ACIDS FOR 4KMZ_A_FOLA301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4kmz FOLATE RECEPTOR BETA

(Homo sapiens) 		PF03024
(Folate_rec) 		4 ASP A  97
ARG A 119
TRP A 156
SER A 190
 FOL  A 301 (-2.8A)
FOL  A 301 (-3.0A)
FOL  A 301 (-3.7A)
FOL  A 301 (-2.6A)
 0.03A 4kmzA-4kmzA:
40.1		 4kmzA-4kmzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lrh FOLATE RECEPTOR
ALPHA

(Homo sapiens) 		PF03024
(Folate_rec) 		4 ASP A  81
ARG A 103
TRP A 140
SER A 174
 FOL  A 301 (-2.7A)
FOL  A 301 (-3.2A)
FOL  A 301 (-3.6A)
FOL  A 301 (-2.8A)
 0.29A 4kmzA-4lrhA:
35.2		 4kmzA-4lrhA:
77.36